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Postdoctoral Researcher/Project Researcher, Mechanisms of Cryptic Female Choice in Humans – University of Eastern Finland

21.6.2022 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=16&id=000013595&lang=en

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=16&id=000013595&lang=fi

The University of Eastern Finland is inviting applications for a Postdoctoral Researcher/Project Researcher (Mechanisms of cryptic female choice in humans) position. The position will be filled for a fixed term from 1.9.2022 (or as agreed, but at the latest 1.11.2022). Please find more information below and submit your application no later than 4.8.2022.

Role and salary

We are seeking a motivated Postdoctoral/Project Researcher to work in our project “Towards molecular-level understanding of fertilization and sexual selection” (funded by the Academy of Finland, more information from research: https://gamcomgroup.wordpress.com). As our new researcher, you will be working in the Department of Environmental and Biological Sciences of Faculty of Science and Forestry. The position is located in Joensuu and/or Kuopio campus, Finland. 

The Postdoctoral/Project Researcher will participate in experimental research that aims to clarify the mechanisms of cryptic female choice in humans. Depending on the expertise of the researcher your main responsibilities can include e.g.:

  • Clarifying molecular (RNA, DNA, or protein) level mechanisms of cryptic female choice,
  • Conducting sperm chemotaxis/selection (cryptic female choice) assays,
  • Phenotypic measurements (e.g. motility, morphology and DNA integrity) of ‘selected’ and ‘non-selected’ sperm, or
  • Identification of candidate genes for male female reproductive incompatibility and cryptic female choice from genomic databases.

Fertilization is one of the most complex and enigmatic biological processes, which severely hinders our understanding about reproduction, evolution and beginning of life. It has traditionally been assumed that fertilization is a completely unbiased process, leading to random fusion of gametes. Against this assumption, our recent findings have indicated that gametes often combine non-randomly, which bias fertilization towards particular (compatible) reproductive partners (see e.g. https://doi.org/10.1098/rspb.2018.0836 and https://doi.org/10.1098/rspb.2020.1682). However, the molecular-level mechanisms of such gamete-level sexual selection have remained unclear. The primary aim of our research is to clarify these mechanisms in humans and this way also gain better understanding of the mechanistic basis of fertilization and infertility (see https://doi.org/10.1093/humrep/deab221).

The position will be filled until 31 December 2023, starting from 1 September 2022 (or as agreed, but at the latest 1.11.2022). The position will be filled for a fixed term due to it pertaining to a specific projectA probationary period is applied to all new members of the staff.  

The salary of the position is determined in accordance with the salary system of the Finnish universities. The salary comprises two components: a job requirement component and a personal performance component. In this position, the job requirement component is 3,044.00 €/month, based on level 5 of the job requirement chart for teaching and research staff. The personal performance component can be a minimum of 6 % and a maximum of 50 % of the above-mentioned sum. Depending on the personal performance component, the salary will be approximately 3534 – 3717 €/month at the beginning of the employment relationship.
 
Our requirements and expectations   

Requirements

  • The person to be appointed as Postdoctoral/Project Researcher is expected to hold a doctoral degree from an applicable field. If the employee has been awarded his or her doctoral degree less than five years ago, the post will be one of a Postdoctoral Researcher. If the doctoral degree has been awarded more than five years ago, the post will be one of a Project Researcher. In this context, the five years refer to a net period of time, which does not include maternity leaves, parental leaves, or military service, etc.
  • Good skills in oral and written English. English is used as the language of instruction and supervision in this position.

Expectations

  • Earlier experience in laboratory work, relevant methods in molecular biology and bioinformatics (e.g. RNA seq, Single Nucleotide Polymorphism microarrays, next-generation sequencing methods, or proteomics) or cell biology (e.g. sperm motility, chemotaxis and viability analyses or flow cytometry) will be considered a benefit for the applicant. If you have any of these skills, please indicate that in the accompanying CV and/or motivation letter (see below).

Your benefits   

You will have access to the university’s staff benefits, including  

  • Extensive occupational health care  
  • Staff discount on lunch in our campus restaurants, as well as on a range of other services  
  • Affordable sports services

Please read more in the Work at UEF section on our website.  

You will have an opportunity to work as part of our international, creative, participatory and inclusive academic community.    

Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system. Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.    

How to apply?   

Submit your application by using our electronic application form no later than 4.8.2022 (by 24.00 hours Finnish time).     

Please note that you must include the following appendices in your application

Questions?   

For further information on the position, please contact: Associate professor Jukka Kekäläinen, email: jukka.s.kekalainen[a]uef.fi, tel. +358 50 467 4487.

For further information on the application procedure, please contact: Human Resources Secretary Noora Hämäläinen, email: noora.hamalainen[a]uef.fi, tel. +358 29 445 8302. (Out of office 11.7.-10.8.2022. During 1.-10.8. please contact Executive Assistant Satu Turunen, email: satu.turunen@uef.fi, tel. +358 29 445 3031).

University of Eastern Finland and the Faculty of Science and Forestry in brief   

The University of Eastern Finland is one of the most multidisciplinary universities in Finland, offering education in nearly 100 major subjects. We have a staff of 2,750 members, and our academic community comprises around 16,000 degree students and more than 27,000 adult education students. Our campuses are located in Joensuu and in Kuopio. Our research is ranked among the best in the world in several fields. We generate research-based knowledge and make it openly accessible for the benefit of all. UEF stands for action with impact that is relevant today and tomorrow. To learn more about our university please visit our website at  www.uef.fi/en.

The Faculty of Science and Forestry operates on the Kuopio and Joensuu campuses of the University of Eastern Finland. The mission of the faculty is to carry out internationally recognised scientific research and to offer research-education in the fields of natural sciences and forest sciences. The faculty invests in all of the strategic research areas of the university. The faculty’s environments for research and learning are international, modern and multidisciplinary. The faculty has approximately 4,400 Bachelor’s and Master’s degree students and some 460 postgraduate students. The number of staff amounts to 560. For more information, see: http://www.uef.fi/en/lumet/etusivu

Haemme Itä-Suomen yliopistoon Tutkijatohtoria/Projektitutkijaa naaraan piilovalinnan (cryptic female choice) mekanismeja ihmisellä käsittelevään tutkimushankkeeseen. Paikka täytetään  määräajalle 1.9.2022 alkaen (tai sopimuksen mukaan, kuitenkin viimeistään 1.11.2022). Lue lisää alta, ja hae viimeistään viimeistään 4.8.2022.

Tehtävä ja palkkaus  

Haemme motivoitunutta tutkijatohtoria/projektitutkijaa Suomen Akatemian rahoittamaan hankkeeseen ”Kohti hedelmöittymisen ja seksuaalivalinnan molekyylitason ymmärtämistä” (lisätietoja tutkimuksesta ja tutkimusryhmästä: https://gamcomgroup.wordpress.com/). Tehtävä sijoittuu Luonnontieteiden ja Metsätieteiden tiedekunnan Ympäristö- ja Biotieteiden laitokselle Joensuun ja/tai Kuopion kampukselle.

Tutkijatohtori/projektitutkija osallistuu kokeelliseen tutkimukseen, jonka tavoitteena on selkiyttää naaraan piilovalinnan mekanismeja ihmisellä. Riippuen tutkijan aiemmasta työkokemuksesta, työhön voi kuulua mm. seuraavia tehtäviä:

  • Naaraan piilovalinnan molekyylitason (RNA, DNA tai proteiini) mekanismien havainnollistaminen,
  • Siittiöiden kemotaksia (naaraan piilovalinta) -kokeiden suorittaminen,
  • ’Valittujen’ ja ’ei-valittujen’ siittiöiden fenotyyppiset mittaukset (esim. liikkuvuus, morfologia ja DNA fragmentaatio), tai
  • Naisten ja miesten sukusolujen geneettistä yhteensopivuutta välittävien kandidaattigeenien identifiointi genomisista tietokannoista

Hedelmöittyminen on eräs monimutkaisimmista ja arvoituksellisimmista biologisista prosesseista, mikä vaikeuttaa lisääntymisen, evoluution ja elämän syntyhetken tapahtumien syvällistä ymmärtämistä. Hedelmöittymisen on perinteisesti ajateltu johtavan sukusolujen satunnaiseen pariutumiseen. Viimeaikaiset tutkimuksemme kuitenkin viittaavat siihen, että sukusolut usein pariutuvat ei-satunnaisesti, niiden keskinäisen geneettisen yhteensopivuuden perusteella (ks. http://dx.doi.org/10.1098/rspb.2018.0836 ja http://dx.doi.org/10.1098/rspb.2020.1682). Sukusolujen ei-satunnaisen pariutumisen mekanistinen tausta on kuitenkin jäänyt epäselväksi. Tutkimuksemme tavoitteena on havainnollistaa näitä mekanismeja ihmisellä ja siten parantaa ymmärrystämme myös hedelmöittymisen ja hedelmättömyyden mekanismeista (ks. https://doi.org/10.1093/humrep/deab221).

Tehtävä täytetään määräajalle 1.9.2022 – 31.12.2023 (tai aloitus sopimuksen mukaan, kuitenkin viimeistään 1.11.2022). Määräaikaisuuden perusteena on määräaikainen hanketehtävä. Uuden työntekijän tullessa yliopiston palvelukseen sovelletaan koeaikaa.

Tehtävän palkkaus määräytyy yliopistojen opetus- ja tutkimushenkilöstön palkkausjärjestelmän mukaisesti. Palkka koostuu tehtäväkohtaisesta palkanosasta ja henkilökohtaiseen suoriutumiseen perustuvasta palkanosasta. Tässä tehtävässä tehtäväkohtainen palkanosa on vaativuustasoluokittelussa tasolla 5 (3044 €/kk). Lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on 6 – 50 % tehtäväkohtaisesta palkanosasta. Vaativuustasosta ja henkilökohtaisesta palkanosasta riippuen palkka työsuhteen alkaessa on noin 3534 – 3717 €/kk.

Mitä edellytämme ja toivomme sinulta  

Edellytämme sinulta

  • Tutkijatohtorilta edellytetään soveltuvaa tohtorin tutkintoa, joka on suoritettu enintään viisi vuotta ennen tutkijatohtorin tehtävän vastaanottamista. Mikäli tohtorin tutkinto on suoritettu yli viisi vuotta tehtävän aloittamisajankohtaa aiemmin, hänet otetaan projektitutkijan tehtävään. Aikaraja tarkoittaa tässä yhteydessä nettoaikaa, johon ei lasketa esim. äitiys- tai vanhempainlomaa tai asevelvollisuuden suorittamista,
  • Hyvää englannin kielen kirjallista ja suullista taitoa.

Katsomme eduksi

  • Aiemman kokemuksen laboratoriotyöskentelystä, tutkimusaiheeseen liittyvistä molekyylibiologisista (esim. RNA sekvensointi, Single Nucleotide Polymorphism – mikrosiruanalyysit, uuden sukupolven sekvensointimenetelmät tai proteomiikka) ja bioinformaattisista tai solubiologisista menetelmistä (esim. siittiöiden liikkuvuus-, kemotaksia- ja elinkykyanalyysit tai virtaussytometria). Jos sinulla on jokin/joitakin näistä taidoista, pyydämme kertomaan siitä ansioluettelossa ja/tai motivaatiokirjeessä (ks. alla).

Tarjoamme sinulle  

  • Mielenkiintoisen ja merkityksellisen työtehtävän osana kansainvälistä ja luovaa yliopistoyhteisöä
  • Kattavan työterveyshuollon
  • Muut Itä-Suomen yliopiston henkilöstöedut, joihin kuuluvat muun muassa laaja henkilöstökoulutustarjonta, edulliset kampusravintolalounaat ja Sykettä-liikuntapalvelut. 

Hae näin  

Jätä hakemus viimeistään 4.8.2022 klo 24 mennessä sähköisellä hakulomakkeella. 

 Huomioi, että hakemukseen tulee liittää mukaan:  

  • Ansioluettelo (http://www.tenk.fi/fi/tutkijan-ansioluettelomalli), 
  • Julkaisuluettelo (https://www.aka.fi/julkaisuluettelo/),
  • Kopiot tutkintotodistuksista ja kielitaitoa osoittavista todistuksista, ellei kielitaito ilmene tutkintotodistuksista  
  • Motivaatiokirje (englanninkielinen, enintään 2 sivua). Kerro kirjeessä, miksi tutkimusaihe kiinnostaa sinua ja miksi olisit sopiva henkilö tehtävään,
  • Muut asiakirjat, joilla haluat osoittaa ansiosi tehtävään.

Kysymyksiä?  

Lisätietoja tehtävästä antaa Apulaisprofessori Jukka Kekäläinen, sähkösposti: jukka.s.kekalainen[a]uef.fi, p. 029 4451004.   

Lisätietoja hakemisesta ja hakuprosessista antaa Henkilöstösihteeri Noora Hämäläinen, sähköposti: noora.hamalainen[a]uef.fi, p. 029 445 8302. (Poissa 11.7.-10.8.2022. Yhteydenotot ajalla 1.-10.8.2022: johdon assistentti Satu Turunen, satu.turunen@uef.fi, puh. 029 445 3031.)

Lyhyesti Itä-Suomen yliopistosta ja Luonnontieteiden ja Metsätieteiden tiedekunnasta  

Itä-Suomen yliopisto on yksi Suomen suurimmista monialaisista tiedeyliopistoista. Tarjoamme opetusta lähes sadassa pääaineessa. Työllistämme 2 750 henkilöä ja yliopistoyhteisöömme kuuluu noin 16 000 perustutkinto-opiskelijaa ja yli 27 000 aikuisopiskelijaa. Toimimme Joensuussa ja Kuopiossa. Tutkimuksemme on useilla aloilla maailman kärkeä. Tuotamme tutkittua tietoa avoimesti käytettäväksi ja kaikkien hyväksi. UEF on vaikuttavia tekoja, joilla on merkitystä nyt ja tulevaisuudessa. Tutustu yliopistoomme osoitteessa www.uef.fi.

Luonnontieteiden ja metsätieteiden tiedekunta toimii Itä-Suomen yliopiston Kuopion ja Joensuun kampuksilla. Tiedekunnan tehtävänä on harjoittaa korkeatasoista kansainvälistä tieteellistä tutkimusta ja tarjota siihen perustuvaa yliopistollista koulutusta luonnontieteiden ja metsätieteiden alalla.  Tiedekunta panostaa yliopiston strategian mukaisiin tutkimusalueisiin. Tiedekunnan tutkimus- ja oppimisympäristöt ovat kansainvälisiä, moderneja ja monitieteisiä. Tiedekunnassa on noin 4 400 perustutkinto-opiskelijaa ja 460 jatko-opiskelijaa. Henkilöstömäärä on noin 560. Lisätietoja tiedekunnasta osoitteessa http://www.uef.fi/fi/lumet/

Senior Scientist (Global Health & Nutrition) – International Flavors & Fragrances

19.6.2022 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3124990055

About the job

The Opportunity

It’s an exciting time to be part of the IFF family. We are a global leader in taste, scent and nutrition, offering our customers a broader range of natural solutions and accelerating our growth strategy. IFF is growing and We are looking for a SENIOR SCIENTIST (Global Health & Nutrition) to join our Global Health & Nutrition Science team based in Kantvik, Southern Finland.

Our team runs a global and diverse program of clinical and pre-clinical studies, targeting to document health benefits of probiotics and other bioactive food ingredients in our portfolio. We can offer you a position in a dynamic international research organization that is a world-wide leader in applied clinical research in the area of probiotics and nutrition.

Are you an action-oriented team player with a scientific background and experience in managing clinical trials? Our R&D team is looking for a research professional to Senior Scientist position to support execution of nutritional clinical trials globally.

Role Responsibilities

As a The Senior Scientist is you will be responsible for providing leadership and scientific expertise for assigned clinical trials to meet regulatory requirements, product registrations, and market access. This position collaborates with cross-functional teams to manage the implementation of clinical and pre-clinical strategies, manage all study aspects, analysis and interpretation of results, and communication of data to the scientific and medical communities.

Your Primary Duties Will Be

  • Defining and developing clinical and pre-clinical deliverables for assigned studies
  • Assessing and recommending CROs and preferred vendors for implementation of related studies
  • Managing all study aspects: budget and metrics, operations, study document development and review (study specific plans, eCRF guidelines, lab manuals, study submission to IRB/ECs in coordination with CRO, interim and final study reports, etc.)
  • Leading statistical activities including statistical analysis plan, analysis and interpretation of results
  • Ensuring that clinical study related activities are carried out in accordance with the appropriate Good Clinical Practice (GCP) guidelines
  • Providing content development and editorial assistance for scientific publications, professional meetings, and/or post-marketing study activities, including abstracts, manuscripts, presentations and training
  • Establish and maintain effective communication and collaboration with functional area peers, including research, laboratory teams, regulatory, quality assurance, and commercial

About You

You are qualified for the position if you have:

  • PhD (or equivalent degree) in life sciences with a minimum of 3 years of relevant experience in research, preferably in the field of nutrition, gut microbiota, probiotics, and/or functional foods
  • Experience in clinical / pre-clinical research and development of probiotics, prebiotics and/or other bioactive compounds for human health applications
  • Experience in one or more of the following health areas is considered an advantage: digestive health, early life nutrition
  • Strong knowledge of statistics and competency working with data
  • Excellent project management, organizational, and team player skills
  • Excellent oral and written communication skills for presentation of scientific concepts and results to internal and external customers and stakeholder
  • Fluency in English is essential; Other language skills are seen as a benefit (fluency in Finnish is an advantage)
  • Track record of scientific publications and experience in scientific communication
  • Ability to deliver results under time and resource pressure

The position is permanent, starting as soon as possible.

For more information on the task, please contact The Director of Clinical Development, Eran Ivanir at Eran.Ivanir@iff.com. Please submit your application with your CV via the IFF recruitment website (https://www.iff.com/careers).

IFF is an Equal Opportunity Employer.

At IFF, we believe that your uniqueness unleashes our potential. We value the diverse mosaic of the ethnicity, national origin, race, age, sex or veteran status. We strive for inclusive workplace that allows each of our colleagues to bring their authentic self to work regardless of their religion, gender identity & expression, sexual orientation, or disability. Visit IFF.com/careers/workplace-diversity-and-inclusion to learn more

VP Global Marketing – Olink Proteomics, EMEA (Remote)

19.6.2022 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3121409467

About the job

Who we are

Olink Proteomics is a rapidly growing life science company committed to advancing the understanding of human diseases through proteomics. We are dedicated to innovation, quality, rigor, and transparency, providing outstanding solutions and support for human protein biomarker discovery.

The vital role of proteins in understanding human biology has been recognized for many decades, but technological limitations severely restricted the comprehensive investigation of the huge number of proteins that could be important in different biological processes and diseases. With Olink, scientists can now simultaneously measure thousands of human proteins using just a few µL of blood sample, with highly specific, thoroughly validated assays that cover a very wide dynamic range (fg/mL to µg/mL).

In a few years, Olink has grown rapidly from a small, Sweden-based company offering assays for a few hundred proteins, to a NASDAQ-listed organization with a strong global presence, a broad portfolio of flexible protein biomarker solutions and library of high quality, thoroughly validated assays that covers ~3000 proteins.

Position Description

As a key member of the commercial team, the VP, Global Marketing will own the strategic direction and tactical implementation of marketing activities across the business. Reporting to the Chief Commercial Officer, you will be accountable for leading, developing and executing the strategic vision and tactical plans for marketing all current and pipeline products. You will own all downstream marketing activities including marketing strategy, branding, product positioning, product messaging, market development, lead generation and nurturing, website management, and marketing communications.

You will take on a broad range of duties and responsibilities not typically seen in larger organizations, so adaptability and strong generalized marketing skills will be crucial. This leader will build and maintain and scale a best-in-class team of marketeers to support commercial growth objectives as the business continues to expand. You thrive in a scale-up environment and have a successful track record of leading innovative marketing plans that position the company and their products ahead of the curve in the proteomics space.

Primary Responsibilities

  • Establish a comprehensive strategic position along with tactical marketing plans that competitively position the company for success.
  • Creating global demand for products in a customer-centric manner by developing and overseeing execution of the marketing plan. This includes definition of and segmentation of the market, targeting and positioning, and all aspects of the marketing mix
  • Lead all product launches, promotional marketing campaigns and marketing communication efforts, aligning them with the company’s commercial strategy.
  • Hire, develop, and motivate a high-performance team of marketeers. Build an effective organizational structure, processes, and a collaborative culture that emphasizes achievement of both short- and long-term business objectives.
  • Cultivate a strong partnership with the Sales organization to constructively partner and contribute to corporate/commercial goals and objectives.
  • Collaborate with other critical functions (ie Product Management, Scientific Affairs) to align objectives and plans
  • Develop and cultivate a strong understanding of the broad range of customer segment needs to create effective value propositions and key messages to drive product adoption
  • Develop and manage a metrics/reporting system to track and maintain an active awareness of marketing program success. Distill findings into actionable insights to evolve program success.
  • Maintain an active awareness of the proteomics-driven precision medicine markets, competitors and customers.
  • Leverage market research and 3rd party data to size the market opportunity and translate this knowledge into creating successful marketing programs. Perform in-depth analysis with both key external and internal stakeholders to understand adoption barriers.
  • Integrate marketing communication promotional plans into the marketing foundation, developing communications tools and defining key conferences that enhance the company’s presence and compliment the overarching marketing business plan.

Qualifications/Skills

  • Bachelor’s degree or higher in a business and/or scientific discipline; PhD and/or MBA preferred
  • 15+ years of proven hands-on experience in marketing roles of increasing scope and responsibility in proteomics, molecular biology, biotechnology or medical device
  • 10+ years of leadership experience in marketing in biotechnology, diagnostics or pharma industry
  • Demonstrated leadership capability and an understanding of the sales process in life science
  • Strong creative intuition on design and messaging that resonates with customers and an ability to learn from previous campaigns to improve on performance
  • Ability to develop, rationalize, and present strategy. Communicates (both written and verbal) in a professional, focused and compelling way that captures and holds others’ attention.
  • Establishes well organized plans of action to complete work objectives effectively.
  • Exceptional skill managing complex marketing projects with a strong attention to detail and outcomes
  • Independently drives execution of project goals and translates priorities into actions and supports all steps of the customer journey
  • Adept at building and maintain relationships with internal and external customers and key opinion leaders
  • Strong analytical and computer skills, with working knowledge of financial models
  • Takes initiative, shows desire to learn and master essential skills, and seeks out opportunities and people that can help business grow
  • Strong multi-tasking abilities, easily juggles multiple priorities, leverages available resources and stays focused under pressure
  • Prior experience in a start-up or tech environment is a plus
  • Requires travel up to 10-20% for industry conferences and visits to subsidiaries

Contact the job poster

Thomas Bennett 2nd

Global Head of Talent Acquisition @Olink ProteomicsJob Poster Location

Thurleigh, England, United Kingdom

S

Solubiologi-lehti

28.2.2022

Solubiologi 2/2021

Vuoden 2021 uusin lehti on julkaistu :). Mukavia lukuhetkiä kaikille!

Mikä Solubiologi-lehti?

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