Ajankohtaista

Postdoctoral Researcher, Studies of Fertility

15.5.2022 | Avoimet työpaikat

Apply here

We, at the University of Oulu, work as part of the international science community to produce new scientific information and science-based solutions. We are committed to educate future pioneers to build a more sustainable, intelligent, and humane world. Creating new, taking responsibility, and succeeding together build a strong foundation in all our actions. We offer a working environment where individuals can cultivate their skills, do meaningful work, and develop professionally. Our university’s several specialized research and service units enable extensive and diverse development and career opportunities for experts in various fields.


We are now seeking a talented scientist for a 3-year fixed-term

Postdoctoral Researcher

position in the group of assistant professor Renata Prunskaite-Hyyryläinen to work on a project focused to understand the genetic and molecular basis of male and female fertility. The research project is carried out under the FIBROBESITY programme – targeting obesity-related fibrotic pathologies. More information can be found at https://www.oulu.fi/en/fibrohealth-combatting-fibrosis-chronic-diseases

The research group is affiliated with the Faculty of Biochemistry and Molecular Medicine. We have two major focus areas: (i) characterization of genes critical for male fertility and (ii) uterine morphogenesis studies through the lifetime and have specific interest in three-dimensional (3D) imaging. Selected publications: doi.org/10.1371/journal.pgen.1008954, doi.org/10.1073/pnas.1608458113, doi.org/10.1038/s41467-021-23571-5, and doi.org/10.1093/hmg/ddv621.

The research project focuses on researching molecular bases of fertility. The main tasks include working with broad variety of molecular and cell biology methods, transgenic mouse models, cell culture, RNA seq data analysis, as well as basic and advanced microscopy.


Requirements
A doctoral degree, or proof of a defense date, preferably in the field of biochemistry, molecular or cell biology, medical sciences, or related fields. Your doctoral degree must be completed before the job contract starts. The doctoral degree must have been received no more than 10 years ago.
– Knowhow in molecular and cellular biology, histology, and imaging methods, as well as experience in research with mouse models are required. Experience in RNAseq data analysis will be viewed as an advantage.
– Certified competence to carry out procedures on animals
– Ability to pursue independent research, work productively in a team, supervise younger scientists, as well as excellent speaking and writing skills in English are expected


What we offer
You will become a part of a growing research group, working on strategically and globally significant research area well integrated to the international scientific community
– You will receive support not only from your team and supervisor, but also from university´s wide variety of support services, so that you can excel in your studies and research/work
– In addition to modern research facilities, we offer you personnel benefits such as occupational healthcare, affordable sport services and salary payments for 12 months/year
– A salary in accordance with the Finnish universities salary system (for teaching and research personnel): level 5. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). In practice, the salary is roughly 3,400 € per month (before taxes) for an early-stage postdoc, depending on the appointee’s qualifications and prior experience. The position is fixed-term 3-year and will start 1st of August or as soon as possible thereafter. A trial period of six months is applied in the position.


Other benefits: The successful candidate will receive full benefits provided by the University of Oulu to university employees, including free time corresponding to holidays and free occupational health care services. The successful candidate will receive also benefits provided by the Finnish government to residents, for example a possibility to obtain access to the national healthcare system, tax benefits for employees with children and high-quality affordable childcare services.

How to apply

Applications must be submitted using the electronic application form by 29th of May 2022 (23:59 Finnish local time), with the following attachments as three separate pdf files:

1) Complete CV according to the guidelines of the Finnish National Board on Research Integrity (https://tenk.fi/en/advice-and-materials/template-researchers-curriculum-vitae) including a list of publications and contact information of at least two referees who may be asked to give a statement on the candidate (max. size limit of the attachment: 5 Mbytes)

2) Motivation letter summarizing professional experience, expertise and describing why you are interested in this position. Information on personal research interests, and career plans is valuable to provide here (1 – 2 pages; max. size limit of the attachment: 2 Mbytes).

3) Certificates/Diplomas: Scanned electronic copies of diplomas and transcripts of the records of relevant previous degrees and, when necessary, official translations to Finnish or English (max. size limit of the attachment: 2 Mbytes)

Applications sent by email will not be considered.

Other relevant information
Eligible applicants fitting best in the research profile expected for the position may be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.

Further information
Informal inquiries can be sent to Renata Prunskaite-Hyyryläinen e-mail [renata.prunskaite(at)oulu.fi] with the subject line “Regarding postdoctoral researcher position”.

Doctoral Reseacher position at Biochemistry and Molecular Medicine

15.5.2022 | Avoimet työpaikat

Apply here

We at the University of Oulu work as part of the international science community to produce new scientific information and science-based solutions. We are committed to educate future pioneers to build a more sustainable, intelligent and humane world. Creating new, taking responsibility and succeeding together are values that build a strong foundation for all our actions. We offer a working environment where individuals can cultivate their skills, do meaningful work, and develop professionally. Our university’s several specialized research and service units enable extensive and diverse development and career opportunities for experts in various fields.

We now have opening for a 4-year

Doctoral researcher position

in microfluidics and biosensors group, led by Prof. Caglar Elbuken (https://www.oulu.fi/fbmm/caglar_elbuken) in the Faculty of Biochemistry and Molecular Medicine at the University of Oulu. The student will be co-supervised by Dr. Ilya Skovorodkin and Prof. Seppo Vainio as well (https://www.oulu.fi/fbmm/seppo_vainio).

Job description:

This position is a unique opportunity at the intersection of biology and engineering opened by two closely collaborating research teams at Faculty of Biochemistry and Molecular Medicine. In addition to a variety of multidisciplinary research topics, our teams focus on development of organoids, lab-on-a-chip systems, microfluidic network growth and organogenesis. Our ERC (https://erc.europa.eu/about-erc/mission) project is on understanding the fundamental principles and implications of bifurcating network growth. Specifically, we are interested in red blood cell flow dynamics in blood vessel network. Organoid vascularization is an important bottleneck in the field that will be studied as an application of the microfluidic bifurcating system in developing of next generation in vitro models: “Human organoids: body-on-a-chip”.

Our goal is to understand the vascularization process during organ development. We aim to reveal the impact of non-uniform oxygenation due to discreteness of red blood cell flow at capillary level and its effect on the corresponding tissue and vessel network growth. Additionally, kidney organoids will be developed to study simultaneous growth of two biological networks where the in vitro vascularization will be quantified on in vitro developed kidney models. Our research groups perform interdisciplinary research at the intersection of developmental biology, cell biology, biochemistry and engineering.

The successful candidate will be provided training on the design, manufacturing and implementation of microfluidic systems. These microfluidic systems will be tested on chicken embryo model and later applied for development of “vessel network on chip” model. Broad range of modern methods of biochemistry, cell and molecular biology will be offered to learn and mastering. The doctoral researcher will be enrolled in the Health and Bioscience Doctoral Programme of the University of Oulu Graduate school, which provides support in theoretical and practical training. The position is fixed-term for 4 years in an ERC funded project and it targets to completion of a Doctoral thesis and multiple publications in high-ranked international journals.

Required qualifications and assessment

The successful applicants must hold a Master’s degree in biology, biochemistry, molecular biology, biophysics or a related field. The applicants close to finishing their Master’s degrees will be considered eligible to apply. The degree must be completed prior to beginning the employment.

Fluent oral and written English skills, good communication and teamwork skills are required. Experience in academic writing and presentation skills is required. Experience with microfluidic systems is an asset. Research experience in a multidisciplinary and multinational environment will be taken as merits. When assessing the applicant’s qualifications, issues to be considered will include research experience, interest and capacity in multidisciplinary research and independent working capability.

What we offer

  • Regular salary is paid 12 months per year, including paid leave and an additional holiday bonus in the summer.
  • University´s wide variety of support services are at your disposal, allowing you to focus on your studies and research / work. You will be provided opportunity free occupational health care provided by the university.In addition to modern research facilities, we offer personnel benefits such as sport services, social activities organized by the university and endless opportunities to develop your skills and competences.
  • The successful candidate will also receive benefits provided by the Finnish government to residents, for example possibility to obtain access to the national healthcare system, the benefits of the Nordic welfare state, tax benefits for employees with children and high-quality, affordable childcare services.

Position and salary

The position is fixed term for a maximum of four-year period. The employment begins on September 1st, 2022 or as soon as possible thereafter. A six-month trial period is applied in the position.

The salary will be set on levels 2 – 4 of the national salary scale for the teaching and research staff of Finnish universities. In addition, supplementary remuneration will be paid for personal achievement and performance (max. 50 %). In practice, the salary is roughly 2300 – 2600 € (before taxes) per month for an early stage researcher, depending on the appointee’s qualifications and progress of the doctoral thesis.

How to apply

Applications must be submitted in English using the electronic application form by June 30th, 2022 (23:59 Finnish local time, EET), with the following attachments as separate pdf files. Applications will be evaluated upon arrival, early application is suggested.

1) CV with contact information of at least three referees

2) Motivation letter with a short description of research merits, experience and motivation (max. 2 pages)

3) Diplomas: Scanned copies of diplomas and transcripts of previous degrees.

4) (optional) A maximum of 3 selected publications (refereed journal articles and/or master’s thesis)

Applications should be submitted through the online system. The short-listed candidates will be invited to an online interview, where they are expected to summarize their research experience and their motivation in applying for this position.

Further information: Please contact Prof. Caglar Elbuken, caglar.elbuken (at) oulu.fi,
or Dr. Ilya Skovorodkin, ilya.skovorodkin (at) oulu.fi, if you need further information on the position.

https://www.oulu.fi/en/news/professor-caglar-elbuken-receives-prestigious-erc-funding-his-multidisciplinary-project-vascular