Ajankohtaista

Postdoctoral Researcher, Studies of Fertility

15.5.2022 | Avoimet työpaikat

Apply here

We, at the University of Oulu, work as part of the international science community to produce new scientific information and science-based solutions. We are committed to educate future pioneers to build a more sustainable, intelligent, and humane world. Creating new, taking responsibility, and succeeding together build a strong foundation in all our actions. We offer a working environment where individuals can cultivate their skills, do meaningful work, and develop professionally. Our university’s several specialized research and service units enable extensive and diverse development and career opportunities for experts in various fields.


We are now seeking a talented scientist for a 3-year fixed-term

Postdoctoral Researcher

position in the group of assistant professor Renata Prunskaite-Hyyryläinen to work on a project focused to understand the genetic and molecular basis of male and female fertility. The research project is carried out under the FIBROBESITY programme – targeting obesity-related fibrotic pathologies. More information can be found at https://www.oulu.fi/en/fibrohealth-combatting-fibrosis-chronic-diseases

The research group is affiliated with the Faculty of Biochemistry and Molecular Medicine. We have two major focus areas: (i) characterization of genes critical for male fertility and (ii) uterine morphogenesis studies through the lifetime and have specific interest in three-dimensional (3D) imaging. Selected publications: doi.org/10.1371/journal.pgen.1008954, doi.org/10.1073/pnas.1608458113, doi.org/10.1038/s41467-021-23571-5, and doi.org/10.1093/hmg/ddv621.

The research project focuses on researching molecular bases of fertility. The main tasks include working with broad variety of molecular and cell biology methods, transgenic mouse models, cell culture, RNA seq data analysis, as well as basic and advanced microscopy.


Requirements
A doctoral degree, or proof of a defense date, preferably in the field of biochemistry, molecular or cell biology, medical sciences, or related fields. Your doctoral degree must be completed before the job contract starts. The doctoral degree must have been received no more than 10 years ago.
– Knowhow in molecular and cellular biology, histology, and imaging methods, as well as experience in research with mouse models are required. Experience in RNAseq data analysis will be viewed as an advantage.
– Certified competence to carry out procedures on animals
– Ability to pursue independent research, work productively in a team, supervise younger scientists, as well as excellent speaking and writing skills in English are expected


What we offer
You will become a part of a growing research group, working on strategically and globally significant research area well integrated to the international scientific community
– You will receive support not only from your team and supervisor, but also from university´s wide variety of support services, so that you can excel in your studies and research/work
– In addition to modern research facilities, we offer you personnel benefits such as occupational healthcare, affordable sport services and salary payments for 12 months/year
– A salary in accordance with the Finnish universities salary system (for teaching and research personnel): level 5. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). In practice, the salary is roughly 3,400 € per month (before taxes) for an early-stage postdoc, depending on the appointee’s qualifications and prior experience. The position is fixed-term 3-year and will start 1st of August or as soon as possible thereafter. A trial period of six months is applied in the position.


Other benefits: The successful candidate will receive full benefits provided by the University of Oulu to university employees, including free time corresponding to holidays and free occupational health care services. The successful candidate will receive also benefits provided by the Finnish government to residents, for example a possibility to obtain access to the national healthcare system, tax benefits for employees with children and high-quality affordable childcare services.

How to apply

Applications must be submitted using the electronic application form by 29th of May 2022 (23:59 Finnish local time), with the following attachments as three separate pdf files:

1) Complete CV according to the guidelines of the Finnish National Board on Research Integrity (https://tenk.fi/en/advice-and-materials/template-researchers-curriculum-vitae) including a list of publications and contact information of at least two referees who may be asked to give a statement on the candidate (max. size limit of the attachment: 5 Mbytes)

2) Motivation letter summarizing professional experience, expertise and describing why you are interested in this position. Information on personal research interests, and career plans is valuable to provide here (1 – 2 pages; max. size limit of the attachment: 2 Mbytes).

3) Certificates/Diplomas: Scanned electronic copies of diplomas and transcripts of the records of relevant previous degrees and, when necessary, official translations to Finnish or English (max. size limit of the attachment: 2 Mbytes)

Applications sent by email will not be considered.

Other relevant information
Eligible applicants fitting best in the research profile expected for the position may be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.

Further information
Informal inquiries can be sent to Renata Prunskaite-Hyyryläinen e-mail [renata.prunskaite(at)oulu.fi] with the subject line “Regarding postdoctoral researcher position”.

Avoimia tutkijanpaikkoja yliopistoissa

11.4.2022 | Avoimet työpaikat

Tähän artikkeliin on koottu muutamia avoimia tutkijan paikkoja yliopistoissa. Käyhän katsomassa löytyisikö näistä juuri sinulle se oikea paikka.

Helsingin yliopisto:

  • Väitöskirjatyöntekijä, Farmaseuttinen biologia (Linkki):
    ”Farmasian tiedekunta hakee väitöskirjatutkijaa määräaikaiseen työsuhteeseen enintään 5 vuodeksi. Työsuhde alkaa 1.9.2022 tai sopimuksen mukaan sen jälkeen. Tehtävän ala on farmaseuttinen biologia ja sijoituspaikka farmaseuttisten biotieteiden osasto. Farmaseuttinen biologia on farmasian osa-alue, jonka tutkimuskohteena on kasvien, mikro-organismien ja eläinten elävät solut biogeenisten lääke- ja apuaineiden tuottajina.”
  • Kaksi post-doc -paikkaa, Centre of Excellence in Stem Cell Metabolism (MetaStem) (Linkki)
    ”The laboratory of Associate Professor Pekka Katajisto at HiLIFE, University of Helsinki, Finland, and the department of Cell and Molecular Biology, Karolinska Institutet, Sweden, is looking for two postdoctoral researchers in the field of Stem Cell Biology and Metabolism.”

Itä-Suomen yliopisto:

  • Väitöskirjatutkija, Molekulaarisen lääketieteen tohtoriohjelma (Linkki)
    ”Tämän hakuilmoituksen kautta voi hakea nuoremman tutkijan (väitöskirjatutkija) tehtävää  molekulaarisen lääketieteen tohtoriohjelmassa. Molekulaarinen lääketiede tutkii sairauksien syntymekanismeja molekyylitasolla, ja saatua tietoa voidaan soveltaa sairauksien hoidossa, diagnostisoinnissa ja ehkäisyssä. Tohtoriohjelmaan kuuluvat tutkimusalat ovat sydän- ja verisuonisairaudet, neurotiede, tyypin 2 diabetes ja lihavuus, kantasolututkimus, tulehdustiloihin liittyvät sairaudet ja syöpä.”
  • Väitöskirjatutkija, Terveystieteiden tohtoriohjelma (Linkki)
    ”Tämän hakuilmoituksen kautta voi hakea nuoremman tutkijan (väitöskirjatutkija) tehtävää terveystieteiden tohtoriohjelmassa. Tohtoriohjelma on monitieteinen ja se kattaa monipuolisesti seuraavat terveystieteiden alat: epidemiologia, geriatria, hoitotiede, kansanterveystiede (ml. ergonomia), liikunta- ja urheilulääketiede, ravitsemustiede (ml. elintarviketieteet), työterveys ja yleislääketiede.”
  • Post-doc -tutkija/Projektitutkija, Extracellular Vesicle Biology (Linkki)
    ”As our new Postdoctoral Researcher or Project Researcher in extracellular vesicle (EV) biology, you will be working in the A.I. Virtanen Institute for Molecular Sciences at the Faculty of Health Sciences. The chosen candidate will be based in the group of Professor Tarja Malm (https://sites.uef.fi/tarja-malm-group/ ). The aim of the project is to discover the potential of EVs as biomarkers in neurodegenerative diseases and the candidate will be working with clinical material.”

Oulun yliopisto:

  • Väitöskirjatutkija, Protein and Structural Biology research unit (Linkki)
    ”We have now an opening for a fixed-term, full-time doctoral researcher position in a research project headed by Professor Lari Lehtiö. Supervisor will be professor Lehtiö and the project is focused on the discovery of small molecule inhibitors of human and virus macrodomains to be used as research tools and as potential future drug leads.”
  • Post-doc -tutkija, Research Unit of Biomedicine (Linkki)
    ”A full-time Postdoctoral Researcher position until the end of 2023, starting at the earliest on August 1st, 2022, in a Biocenter Oulu research project headed by Professor Risto Kerkelä and Professor Juhani Junttila. Our research focuses on molecular mechanisms and genetics regulating development of cardiac fibrosis, heart failure and sudden cardiac death.”

Turun yliopisto:

Åbo Akademi:

  • Väitöskirjatutkija (8 paikkaa), The Faculty of Science and Engineering (Linkki)
    ”The Faculty of Science and Engineering offers 8 new, funded positions for doctoral students (max. 48 months/position) including one within the Finland Fellowship programme for non-EU/EEA doctoral students. The positions are available within the following doctoral programmes: Biosciences (main subjects: Biochemistry, Cell Biology, Environmental and Marine Biology), Chemical and Process Engineering (main subjects: Chemical Engineering (kemiteknik), Chemical Engineering (process- och energiteknik), Information Technology (main subjects: Computer Engineering, Computer Science), Mathematics, Physics, Chemistry and Geology (main subjects: Chemistry, Geology and Mineralogy, Mathematics and Statistics, Physics) and Pharmaceutical Development and Medical Technology (main subjects: Drug Development, Pharmacy).”

Postdoctoral Researcher, Tissue Engineering

27.2.2022 | Avoimet työpaikat

Hakulinkki – Apply here

The University of Eastern Finland is inviting applications for a Postdoctoral Researcher, Tissue Engineering, position on the Kuopio campus at the Department of Applied Physics. The position will be filled part-time (50%) for a fixed 2-year term from 1 April 2022 (or starting date as agreed). Please find more information below and submit your application no later than 15 March 2022.

Role and salary  

We are seeking for a highly motivated Postdoctoral Researcher to work part-time on an Academy of Finland funded research project entitled ‘A novel infrared spectroscopic and modelling approach for online monitoring and control of cartilage tissue growth in a bioreactor.

The project will be conducted at the Biomedical Spectroscopy Laboratory (BSL) and Biophysics of Bone and Cartilage (BBC) research groups, Department of Applied Physics, University of Eastern Finland, under the supervision of Academy Research Fellow Isaac Afara and other senior members of the research team. BSL is a highly multidisciplinary team of more than 15 researchers with background in engineering, physics and mathematics, applying biophotonics principles for tissue characterization and diagnostics. The BBC group is a global leader in the biophysics of bone and cartilage, and consists of more than 50 researchers applying experimental, computational and clinical approaches for understanding and development of innovative techniques for diagnosis of joint diseases.

The primary aim of this project is to combine cutting-edge knowledge on infrared spectroscopy with state-of-the-art paradigm in cartilage tissue engineering (functional tissue engineering) for in situ live monitoring and control of cartilage tissue engineering process. This will be achieved via a multi-disciplinary approach that combines tissue engineering, biophotonics, data science and bioprocess control, and nano-spectroscopic imaging through active national and international collaboration. The project involves active collaboration with the Academy of Finland Center of Excellence in Body-On-Chip Research (Professor Minna Kellomäki and Associate Professor Susanna Miettinen). The primary tasks of the PhD student will include, but not limited to, tissue engineering laboratory experiments involving, but not limited to, creation of cell-hydrogel scaffolds and monitoring of tissue growth using near infrared (NIR) spectroscopy during tissue engineering of articular cartilage. The Postdoctoral Researcher will also be actively involved in preparation of personal grant applications, and other tasks assigned by the supervisor.

Candidates who are currently completing or have recently completed a PhD degree are invited to apply, provided that they will have completed their degree before starting date.

The position will be filled part-time (50%) for a 2-year term from 1 April 2022 (or starting date as agreed). The position will be filled for a fixed term due to it pertaining to a specific project. A probationary period is applied to all new members of the staff.

The salary of the position is determined in accordance with the salary system of the Finnish universities. The salary comprises two components: a job requirement component and a personal performance component. In this position, the job requirement component is 3,000.49 euros/month, based on level 5 the job requirement chart for teaching and research staff. The personal performance component can be a minimum of 6 % and a maximum of 50 % of the above-mentioned sum. Depending on the personal performance component, the salary will be approximately 3,181 – 3,661 €/month at the beginning of the employment relationship.

Our requirements and expectations  

  • The person to be appointed in the position shall hold a PhD degree in biomedical/biological sciences, biochemistry, tissue engineering with strong biological background or related fields. The doctoral degree may not have been completed more than five years ago at the time of accepting the position (a net period of time, which does not include parental leaves, military service etc.),
  • Potential candidates should have a good command of the English language.

Experience and Skills

Minimum:

  • Background in tissue engineering
  • Previous experience working with animal/human cells
  • Prior experience in preparation of biological assays
  • Fluency in spoken and (especially) written English for technical communication.

Desirable:

  • Strong experience in biological laboratory experiments
  • Good publication track record
  • Strong experience in statistical analysis

Your benefits 

You will have access to the university’s staff benefits, including:

  • extensive occupational health care, 
  • staff discount on lunch in our campus restaurants, as well as on a range of other services,
  • affordable sports services.

Please read more in the Work at UEF section on our website.

You will have an opportunity to work in an interesting and diverse role as part of our international, creative, participatory and inclusive academic community. 

Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more. 

How to apply? 

Submit your application by using our electronic application form no later than 15 March 2022 (by 23.00 CET). 

Please note that you must include the following appendices in your application: 

Questions? 

For further information on the position, please contact Academy Research Fellow Isaac Afara, email: isaac.afara@uef.fi, tel.+358 29 445 3305. 

For further information on the application procedure, please contact Executive Assistant Satu Turunen, email: satu.turunen@uef.fi, tel. +358 29 445 3031.

Post-graduate or post-doctoral scientist for cell therapy research project

8.2.2022 | Avoimet työpaikat

https://www.veripalvelu.fi/meille-toihin/avoimet-tyopaikat/post-graduate-or-post-doctoral-scientist-for-a-cell-therapy-research-project

We are looking for a research scientist in cell or molecular biology to a research project focusing on genetic modification of T cells and NK cells with Chimeric Antigen Receptors.

​The Finnish Red Cross Blood Service has a strategic interest in the development of novel cell therapeutics. Presently, mesenchymal stromal cells are being manufactured at the Advanced Cell Therapy Centre for treatment of patients, and we are also collaborating with industry in an R&D project aiming at developing a Chimeric Antigen Receptor (CAR)-equipped T-cell product for patient treatment.

The Project / the Position

The research project is funded as part of the Academy of Finland Flagship program GeneCellNano (2020-2024). The person hired for this post will be employed by the University of Eastern Finland but carry out their work at the Finnish Red Cross Blood Service in Helsinki. The current funding covers one year and the work contract will be made for that period, and more research funding is applied for the continuation of the project. We will employ a post-doctoral scientist or a post-graduate researcher aiming at a PhD degree for the project. The scientist is expected to devote a part (10-20%) of his/her time to laboratory management.

We hope you could start your work in March-April of 2022.

The project is conducted in collaboration with research groups from the Universities of Helsinki and Eastern Finland. Your work involves planning the research, carrying out experiments and interpreting and reporting the results. You will operate within the iCell research group (https://www.bloodservice.fi/Research%20Projects/cell-therapy/icell ) that focuses on developing novel immune cell technologies.

Skills and experience

You have a suitable university degree and strong experience of cell culture experiments. Experience of immunology and molecular biology will be helpful. The project will employ animal tumor models. The work requires a self-driven and motivated scientist with previous experience of research. Collaboration and communication skills are also important. Describe in your application the experimental techniques in cell culture, immunology and molecular biology that you master, and how long you experience in these techniques is, your motivation for academic research and lab-work, as well as possible references.

How to apply and inquiries

For more information please contact senior medical officer Matti Korhonen matti.korhonen@veripalvelu.fi, tel. 050 396 9450 (telephone time 8.2. between 15-15.30, 10.2. between 16-16.30, 15.2. between 16-16.30, and 17.2. between 11-11.30). Eventual interviews will be conducted virtually.

Submit your application by 17.2.2022 via our application form.

A post-doctoral position in the collaborative Academy of Finland -funded crossbar project

7.1.2022 | Avoimet työpaikat

https://www2.helsinki.fi/en/open-positions/a-post-doctoral-position-in-the-collaborative-academy-of-finland-funded-crossbar-project

A POST-DOCTORAL POSITION

is available in the collaborative Academy of Finland -funded CrossBar project at the Universities of Helsinki and Turku, and the National Institute of Health and Welfare (THL). The project PI’s are Associate Professor Tarja Sironen (UH), Adjunct Professor Laura Kakkola (UT) and Research Manager, PhD, Pamela Österlund (THL). The position is offered for a fixed-term position for 3 years (approximately one year in each of the partner institutes).

We seek for a highly motivated and experienced postdoctoral researcher in the field of virology, microbiology, immunology or molecular cell biology to join our international and dynamic consortium. The job description is to plan and execute research on zoonotic viruses with pandemic potential.

The successful candidate:

  • Has strong organizational skills, is solution-oriented and has the ability to analytical thinking
  • Has a PhD degree in a relevant field of life sciences and preferably background in virology
  • Has excellent skills in experimental laboratory work and ability to independently plan and execute the experiments
  • Has previous experience in working in BSL-3 conditions or is willing to be trained for work in such conditions Is a team player with good collaboration and communications skills
  • Has good spoken and written English

The degree requirement must be met by the beginning of the employment.The salary is based on the Finnish collective agreement. The position belongs to the category of teaching and research personnel. The salary is in the range of 3100 – 3600 eur/month.The salary level is based on previous qualifications, experience and personal performance in the position according to the hosting institution. The start date is negotiable, and there is a trial period of six months.

The application, together with the required attachments in PDF format (CV, list of publications), must be written in English and submitted through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) must submit their applications through the SAP HR portal.

A special health examination of the suitability to work in the high containment laboratory is required for the person selected to the position. Also, the selected person, with his or her consent, will be asked for PSC (Personnel Security Clearance) assurance through the National Security Authorities (NSA).

The University of Helsinki welcomes applicants from a variety of genders, linguistic and cultural backgrounds, and minorities.

The deadline for the applications is 15.1.2022.

Further information will be given by email of by phone:

  • Tarja Sironen, tarja.sironen(at)helsinki.fi, +358-50-4471588
  • Laura Kakkola, laura.kakkola(at)utu.fi, +358-50-5747101
  • Pamela Österlund, pamela.osterlund(at)thl.fi, +358-295248351

Postdoctoral Researcher / Project Researcher / Early Stage Researcher (Biomedical Informatics)

14.12.2021 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=16&id=000012134&lang=fi

The University of Eastern Finland is inviting applications for a Postdoctoral Researcher / Project Researcher / Early Stage Researcher (Biomedical Informatics) position in Kuopio. The position will be filled for a two-year term from 1 January 2021 (or as agreed). Please find more information below and submit your application no later than 28 December 2021. (Extended application period)

Role and salary

As our new Postdoctoral, Project or Early Stage Researcher in Biomedical Informatics, you will be working in the research group led by Associate Professor and Academy Research Fellow Vittorio Fortino in the Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, Kuopio Campus.

Our group studies and implements data mining algorithms (including machine learning algorithms) to tackle biomedical questions, such as biomarker and drug discovery. Applicants with profound knowledge of (1) bioinformatics tools to analyse genomics and transcriptomics data; and (2) machine learning algorithms are encouraged to apply.

More details on the research group and research interests can be found at 

The successful candidate will work on a project funded by Jane and Aatos Erkko Foundation. 

https://www.uef.fi/en/article/precision-cancer-medicine-with-machine-learning-and-ai

The position is part of a project aiming to develop machine learning approaches

1)      to identify clinically relevant cancer subtypes from multi-omics datasets (TCGA);

2)      to learn how to match cancer cell lines with cancer subtypes via omics data (TCGA, CCLE, GDSC, and GTEx); and

3)      to discover synergistic (and safer) drug combinations from available pharmacogenomics data (e.g. LINCS 1000).

The position will be filled for a two-year term from 1 January 2021 (or as agreed) due to it pertaining to a specific project.  A probationary period is applied to all new members of the staff.

The salary of the position is determined in accordance with the salary system of the Finnish universities. The salary comprises two components: a job requirement component and a personal performance component. For a Postdoctoral Researcher / Project Researcher, the job requirement component is 3,000.49 €/month, based on level 5 of the job requirement chart for teaching and research staff. For an Early-stage Researcher, the job requirement component is 2,078.27 – 2,591.28 €/month, based on levels 2-4 of the job requirement chart for teaching and research staff. The personal performance component can be between 6-50 % of the above-mentioned sums.

At the beginning, the salary will be 3,180.52 – 3,660.60 € /month, as Postdoctoral / Project Researcher or 2,202.97-2,746.76 € /month as Early-Stage Researcher.

Our requirements and expectations

The appointed researcher will have a central role in implementing and applying machine learning methods for the analysis of large-scale omics data. They will have an inquisitive mindset, a proactive attitude, and the desire to further develop their skills for data science and machine learning.

The successful candidate will:

  • Have a PhD in Bioinformatics, Computational Science or a related discipline for the Postdoctoral/Project Researcher position. If the doctoral degree has been awarded less than five years ago, the post will be one of a Postdoctoral Researcher. If the doctoral degree has been awarded more than five years ago, the post will be one of a Project Researcher. In this context, the 5 years refer to a net period time, which does not include parental leaves, or military service.
  • Have an MSc in Bioinformatics, Biosciences or a related discipline for the Early Stage Researcher position; have completed a suitable higher university degree or an equivalent education abroad which in the country in question would qualify the person for similar academic studies. The candidate shall also be qualified to pursue postgraduate studies at the University of Eastern Finland by enrolling in one of the doctoral programmes of the Faculty of Health Sciences.

Desired knowledge, skills, and abilities that are essential for this position:

  • A solid computational (informatics/computer science/coding) background is required..
  • Solid knowledge of, and practical experience in, bioinformatics is required.
  • Experience of analysis of at least two different types of omics data (e.g. gene expression data, genomic data – GWAS, DNA methylation data, etc.) is required.
  • Programming experience in a relevant programming language (e.g., R and Python) is required.
  • Practical experience of working with machine learning methods is required.
  • Practical experience of working with network analysis is an advantage.
  • Applicants must be able to work independently and in a team.
  • Applicants must have good skills in oral and written English.
  • Previous research experience and ambitions will also count during the evaluation process.

Your benefits

You will have access to the university’s staff benefits, including

  • extensive occupational health care
  • staff discount on lunch in our campus restaurants, as well as on a range of other
    services
  • affordable sports services.

Please read more in the Work at UEF section on our website. https://www.uef.fi/en/university#paragraph-4467

How to apply? 

Submit your application by using our electronic application form no later than 28.12.2021 (by24.00 hours Finnish time).

 Please note that you must include the following appendices in your application:

Questions?

For further information on the position, please contact: Associate Professor Vittorio Fortino, +358 29 445 4197,  vittorio.fortino@uef.fi.

For further information on the application procedure, please contact  Saima-asiatTT@uef.fi

Postdoctoral Research Fellow, (Functional RNAomics), 2 positions

14.12.2021 | Avoimet työpaikat

https://tuni.rekrytointi.com/paikat/?o=A_RJ&jgid=1&jid=1210

The Functional RNAomics laboratory at the Faculty of Medicine and Health Technology, Tampere University studies gene regulation via RNA processing. By determining how RNA regulation is orchestrated in different cell types, we aim to crack the cellular RNA code and gain critical insights into how aberrations in the RNA machinery result in genetic disorders and cancer. RNA is emerging as a powerful and easily adaptable therapeutic molecule as exemplified by the rapid development of effective mRNA vaccines but a detailed knowledge of RNA regulation in cells is a prerequisite to realise the full potential of RNA-based therapeutic and diagnostic development. We integrate cell biology approaches with mechanistic studies, global mapping of RNA repertoires, RNA binding protein interactions and proteomics profiles to reveal the functional role of RNA-protein complexes in different cell lineages and in disease.

Job description

We are looking for two post-doctoral researchers on full- or part-time basis:

  1. The postdoctoral researcher in cell and molecular biology will conduct experimental research involving advanced molecular biology techniques including sample preparation for short-read and long-read RNA sequencing, cell and organoid cultures, and various biochemistry methods. The work involves experimental planning, detailed recording of data, data analysis and reporting of results.
  2. The post-doctoral research in bioinformatics will analyse a range of large-scale datasets including short-read RNA sequencing, long-read direct RNA sequencing and proteomics data. The work includes the application of existing data analysis pipelines as well as the development of new computational methods. It also involves experimental planning, detailed recording of data and reporting of results.

Requirements

The positions are mostly intended for recently graduated researchers, so that they may gain further experience and advance their careers. You should have a PhD degree in biochemistry, genetics, molecular biology, bioinformatics/computational biology or a related subject area. We expect a competence to pursue independent scientific work. You should be fluent in spoken and written English and have a solid experience either in (1) cell and molecular biology or (2) computational biology/bioinformatics. Skills in both wet and dry lab research are considered an advantage. 

You should be able to communicate with experimental and computational biologists as a member of a multidisciplinary team. We appreciate experience of studying or working abroad and contacts to international research community. We are looking for versatile and independent researchers with experience in the closely related area of the positions. It is expected that you will be able to contribute to the supervision of M.Sc. and Ph.D. students. Please be prepared to provide a proof of your merits when requested.

Tampere University is a unique, multidisciplinary and boldly forward-looking, evolving community. Our values are equity, openness, diversity, responsibility, courage, critical thinking, erudition bildung, and learner-centredness. We hope that you can embrace these values and promote them in your work.

We offer

The position will be filled for a fixed-term period of 2 years in the first instance. The starting date is 1st February 2022 or as mutually agreed. A trial period of six months applies to all our new employees.

The salary will be based on both the job requirements and the employee’s personal performance in accordance with the Finnish University Salary System. The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff). 

We offer a wide range of staff benefits, such as occupational health care, flexible working hours, excellent sports facilities on campus and several restaurants and cafés on campus with staff discounts. Please read more about working at Tampere University.

We offer a world-class research environment in an internationally recognized research group. We have strong collaborative networks and offer great opportunities for researchers to develop their careers in an international setting.

How to apply

Please submit your application through our online recruitment system. The closing date for applications is 10th December 2021 (at 23.59 EET /UTC+2). Please write your application and all accompanying documents in English and attach them in PDF format.

The closing date for applications has been extended until 20 December, 2021.

Applications should include the following documents:

  • Curriculum Vitae according to TENK guidelines
  • List of publications according to Academy of Finland guidelines
  •  References from two people
  •  Motivation letter (1-2 pages) 
  • Description of your research focus, qualifications, previous research fields and main research achievements (1-2 pages)

For more information, please contact:

Professor, Group Leader Minni Änkö, minna-liisa.anko (at) tuni.fi

***

Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fi 

Functional RNAomics -tutkimusryhmä Tampereen yliopiston Lääketieteen ja terveysteknologian tiedekunnassa tutkii RNA-välitteistä geenien säätelyä. Tutkimuksemme tavoitteena on selvittää, miten RNA-tason säätely toimii eri solutyypeissä. Tarkoituksenamme on ‘murtaa solujen RNA-koodi’ ja siten ymmärtää, mikä RNA-säätelyn rooli on geneetisien sairauksien ja syövän synnyssä. RNA on osoittautunut monimuotoiseksi molekyyliksi, jota voidaan soveltaa erilaisten sairauksien hoidossa tai ehkäisyssä, esimerkkinä hiljattain kehitetyt RNA-rokotteet. Jotta RNA:ta voidaan turvallisesti hyödyntää diagnostiikassa ja hoitomuotona, meidän täytyy kuitenkin ensin selvittää, kuinka RNA-säätely toimii solutasolla. Yhdistämme tutkimuksessamme erilaisia solu- ja molekyylibiologian menetelmiä sekä RNA- ja proteomitason profilointia.

Tehtävänkuvaus

  1. Tutkijatohtori/solu- ja molekyylibiologia: molekyyli- ja solubiologian tutkimuksen suunnitteleminen, laboratoriatehtävät mukaan lukien soluviljely, sekvenointikirjastojen valmistaminen erilaisiin RNA-sekvenointisovelluksiin sekä erilaiset biokemian menetelmät, tulosten analysointi ja raportointi.
  2. Tutkijatohtori/bioinformatiikka: RNA-sekvenointi- ja proteomidatan analysointi käyttäen olemassaolevia menetelmiä, uusien analyysimenetelmien kehittäminen, tulosten reportointi.

Tutkimusryhmän työkieli on englanti, joten sujuva englanninkielen taito on välttämätön. Tutkijatohtorin tehtäviin kuuluu nuorempien tutkijoiden ja opiskelijoiden ohjaus. 

Hakuohjeet

Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta.

Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).

Hakuaika tehtävään päättyy 10.12.2021 klo 23.59.

Hakuaikaa jatkettu 20.12.2021 klo 23.59 asti.

Postdoctoral Research Fellow, (Functional RNAomics) – 2 positions

12.11.2021 | Avoimet työpaikat

https://tuni.rekrytointi.com/paikat/?o=A_RJ&jgid=1&jid=1210

The Functional RNAomics laboratory at the Faculty of Medicine and Health Technology, Tampere University studies gene regulation via RNA processing. By determining how RNA regulation is orchestrated in different cell types, we aim to crack the cellular RNA code and gain critical insights into how aberrations in the RNA machinery result in genetic disorders and cancer. RNA is emerging as a powerful and easily adaptable therapeutic molecule as exemplified by the rapid development of effective mRNA vaccines but a detailed knowledge of RNA regulation in cells is a prerequisite to realise the full potential of RNA-based therapeutic and diagnostic development. We integrate cell biology approaches with mechanistic studies, global mapping of RNA repertoires, RNA binding protein interactions and proteomics profiles to reveal the functional role of RNA-protein complexes in different cell lineages and in disease.

Job description

We are looking for two post-doctoral researchers on full- or part-time basis:

  1. The postdoctoral researcher in cell and molecular biology will conduct experimental research involving advanced molecular biology techniques including sample preparation for short-read and long-read RNA sequencing, cell and organoid cultures, and various biochemistry methods. The work involves experimental planning, detailed recording of data, data analysis and reporting of results.
  2. The post-doctoral research in bioinformatics will analyse a range of large-scale datasets including short-read RNA sequencing, long-read direct RNA sequencing and proteomics data. The work includes the application of existing data analysis pipelines as well as the development of new computational methods. It also involves experimental planning, detailed recording of data and reporting of results.

Requirements

The positions are mostly intended for recently graduated researchers, so that they may gain further experience and advance their careers. You should have a PhD degree in biochemistry, genetics, molecular biology, bioinformatics/computational biology or a related subject area. We expect a competence to pursue independent scientific work. You should be fluent in spoken and written English and have a solid experience either in (1) cell and molecular biology or (2) computational biology/bioinformatics. Skills in both wet and dry lab research are considered an advantage. 

You should be able to communicate with experimental and computational biologists as a member of a multidisciplinary team. We appreciate experience of studying or working abroad and contacts to international research community. We are looking for versatile and independent researchers with experience in the closely related area of the positions. It is expected that you will be able to contribute to the supervision of M.Sc. and Ph.D. students. Please be prepared to provide a proof of your merits when requested.

Tampere University is a unique, multidisciplinary and boldly forward-looking, evolving community. Our values are equity, openness, diversity, responsibility, courage, critical thinking, erudition bildung, and learner-centredness. We hope that you can embrace these values and promote them in your work.

We offer

The position will be filled for a fixed-term period of 2 years in the first instance. The starting date is 1st February 2022 or as mutually agreed. A trial period of six months applies to all our new employees.

The salary will be based on both the job requirements and the employee’s personal performance in accordance with the Finnish University Salary System. The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff). 

We offer a wide range of staff benefits, such as occupational health care, flexible working hours, excellent sports facilities on campus and several restaurants and cafés on campus with staff discounts. Please read more about working at Tampere University.

We offer a world-class research environment in an internationally recognized research group. We have strong collaborative networks and offer great opportunities for researchers to develop their careers in an international setting.

How to apply

Please submit your application through our online recruitment system. The closing date for applications is 10th December 2021 (at 23.59 EET /UTC+2). Please write your application and all accompanying documents in English and attach them in PDF format.

Applications should include the following documents:

  • Curriculum Vitae according to TENK guidelines
  • List of publications according to Academy of Finland guidelines
  •  References from two people
  •  Motivation letter (1-2 pages) 
  • Description of your research focus, qualifications, previous research fields and main research achievements (1-2 pages)

For more information, please contact:

Professor, Group Leader Minni Änkö, minna-liisa.anko (at) tuni.fi

***

Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fi 

Functional RNAomics -tutkimusryhmä Tampereen yliopiston Lääketieteen ja terveysteknologian tiedekunnassa tutkii RNA-välitteistä geenien säätelyä. Tutkimuksemme tavoitteena on selvittää, miten RNA-tason säätely toimii eri solutyypeissä. Tarkoituksenamme on ‘murtaa solujen RNA-koodi’ ja siten ymmärtää, mikä RNA-säätelyn rooli on geneetisien sairauksien ja syövän synnyssä. RNA on osoittautunut monimuotoiseksi molekyyliksi, jota voidaan soveltaa erilaisten sairauksien hoidossa tai ehkäisyssä, esimerkkinä hiljattain kehitetyt RNA-rokotteet. Jotta RNA:ta voidaan turvallisesti hyödyntää diagnostiikassa ja hoitomuotona, meidän täytyy kuitenkin ensin selvittää, kuinka RNA-säätely toimii solutasolla. Yhdistämme tutkimuksessamme erilaisia solu- ja molekyylibiologian menetelmiä sekä RNA- ja proteomitason profilointia.

Tehtävänkuvaus

  1. Tutkijatohtori/solu- ja molekyylibiologia: molekyyli- ja solubiologian tutkimuksen suunnitteleminen, laboratoriatehtävät mukaan lukien soluviljely, sekvenointikirjastojen valmistaminen erilaisiin RNA-sekvenointisovelluksiin sekä erilaiset biokemian menetelmät, tulosten analysointi ja raportointi.
  2. Tutkijatohtori/bioinformatiikka: RNA-sekvenointi- ja proteomidatan analysointi käyttäen olemassaolevia menetelmiä, uusien analyysimenetelmien kehittäminen, tulosten reportointi.

Tutkimusryhmän työkieli on englanti, joten sujuva englanninkielen taito on välttämätön. Tutkijatohtorin tehtäviin kuuluu nuorempien tutkijoiden ja opiskelijoiden ohjaus. 

Hakuohjeet

Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta.

Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).

Hakuaika tehtävään päättyy 10.12.2021 klo 23.59.

Postdoctoral Researcher in Cancer Immunology

1.11.2021 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/application_edit_welcome.html?field_id=0&job_name=Postdoctoral+Researcher+in+Cancer+Immunology&job_id=12111&jc=14&lang=en&place_id=158&did=5600

The Melanoma Immune Oncology Research Group (MIORG) as part of the Institute of Biomedicine, University of Turku is seeking an enthusiastic and competent Postdoctoral Researcher to collaborate in a project related to melanoma immunobiology and immunotherapy, led by Dr Rogerio de Figueiredo. The project employs cutting-edge technologies and state-of-the-art approaches to immune profile metastatic melanoma bioresources from animal models and patient samples.

Key Responsibilities

  • Conduct scientific research related to metastatic melanoma immunotherapy, including cancer immunobiology, drug discovery using in vitro and in vivo assays biochemical and pharmacological assays, and data analysis.

Essential Qualifications

  • PhD degree in a relevant discipline (e.g. cell biology, molecular biology, biomedicine, biochemistry and immunology)

Desirable Qualifications

  • Animal and human work experience. License for animal work is desirable.
  • Competence in tissue culture methods and experience in processing human/animal samples.
  • Sufficient skills with RNA isolation, quantitative RT-PCR, protein isolation and western blot and ELISA assays.
  • Good experience with tissue immunofluorescence and immunohistochemistry techniques.
  • Experience in single cell staining for Flow Cytometry and CyTOF.
  • Organization skills for inventory of consumables and protocols
  • Experience with statistics and bioinformatics.

The successful candidate should show initiative and independence on the bench, possess good communication skills and the ability to work effectively as part of a team.

Salary

The salary is based on the Finnish collective agreement. The position belongs to the category of teaching and research personnel. Thus the total salary is estimated to be in the range of 3180-3500 €/month. The salary will be defined based on the applicant’s competence and work experience.

Duration of the Contract

  • The successful applicant is expected to start as soon as possible, but the starting date is negotiable.
  • The position is fixed-term for max. 2 years according to the funding granted to the project. There is a possibility for extension.
  • The position is subject to a six-month trial period.

What to do next

Applications must be submitted by 19 November 2021 at the latest (23.59.59 Finnish time) via the University of Turku electronic application form. Apply for the job at www.utu.fi/careers (“Fill the form”).

In your application, please include

  • a motivation letter
  • CV
  • copies of degree certificates
  • at least one recommendation letter

The top candidates will be interviewed.

For further information about the position, please contact the Group Leader, Adjunct Professor, Academy Research Fellow Rogerio de Figueiredo (rogerio.defigueiredo@utu.fi).

In case you need help with the application process, please turn to HR Specialist Kristiina Nuutila (kristiina.nuutila@utu.fi), Tel. +358 503135224.

Post­doc­to­ral Re­searc­her in Pro­tein Bioc­he­mi­stry and Struc­tu­ral Bio­lo­gy

9.8.2021 | Avoimet työpaikat

https://www2.helsinki.fi/fi/avoimet-tyopaikat/postdoctoral-researcher-in-protein-biochemistry-and-structural-biology

The laboratory of Dr. Tommi Kajander at the Institute of Biotechnology, HiLIFE, University of Helsinki, Finland, is inviting applications for post-doctoral researcher in the area of protein biochemistry and structural biology in a joint project with Prof. Mart Saarma’s laboratory. We are seeking for dedicated and enthusiastic scientist to work on the structure and function of novel endoplasmic reticulum effector protein-receptor interactions in ER stress response regulation. Main targets are CDNF and MANF proteins and their interaction complexes in the ER.

The Institute of Biotechnology is a research institute at University of Helsinki, located in the Viikki science park. The institute harbors ~35 research groups and 250 researchers, and it operates at the highest international level. For more information on the Institute, please visit https://www.helsinki.fi/en/hilife-institute-of-biotechnology.
The institute has excellent infrastructure for structural biology (X-ray, CryoEM, NMR) including the crystallography core facility run by the PI.

The post-doctoral applicants should hold PhD in biochemistry or a related field. Strong experience in protein biochemistry including cloning and mutagenesis and protein expression and purification, from various hosts and good communication skills in English are required. Knowledge and experience in structural biology and molecular biophysics techiques and cell culture is beneficial. This is an opportunity to work on high impact targets and obtain in depth technical skills in the research area. The position will provide excellent opportunities for collaborations, as this is a joint project in close collaboration with Prof. Mart Saarma’s group, with also potential international and national collaborations and visits to e.g. synchrotron sources in Europe (ESRF, DLS, MAXIV). An attitude to carry out ambitious research projects, good problem solving skills, goal-oriented mind-set and willingness to learn and apply new methodologies is highly appreciated. The working language of the laboratory is English; knowledge of Finnish is not a requirement.

The postdoctoral position is initially limited to 1 year, with a possibility of extension to three years. The salaries will be based on the University salary scheme (level 5) for teaching and research personnel composed of both task specific and personal performance component The position is available immediately or as agreed.

Application should include the following documents as a single pdf file (max 5 pages): CV (max 2 pages), list of publications, motivation letter (max 1 page) including a description of your research interests, and the names and contact details of at least two referees. Please submit your application, together with the required pdf attachment, through the University of Helsinki electronic recruitment system by clicking on the ‘Apply for job’ button. Internal applicants (i.e., current employees of the University of Helsinki) should submit their applications through the SAP HR portal. For technical support regarding the recruitment system, please contact ‘rekrytointi@helsinki.fi’.

The deadline for the applications is 31st of August, 2021, or until suitable candidate have been found.

For informal inquiries, contact ‘tommi.kajander(at)helsinki.fi’
See also:
https://www2.helsinki.fi/en/researchgroups/structural-biology-of-protein…
https://www2.helsinki.fi/en/researchgroups/neurotrophic-factors-and-rege…

For technical support regarding the recruitment system, please contact rekrytointi@helsinki.fi.

Selected recent references related to project and the laboratory:
Kovaleva V, Yu LY, Ivanova L, Nam J, Eesmaa A, Kumpula EP, Huiskonen J, Lindholm P, Voutilainen M, Karelson M, Saarma M. MANF regulates unfolded protein response and neuronal survival through its ER-located receptor IRE1α bioRxiv 2020.09.22.307744

Eesmaa A, Yu LY, Göös H, Nõges K, Kovaleva V, Hellman M, Zimmermann R, Jung M, Permi P, Varjosalo M, Lindholm P, Saarma M. The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor. J Biol Chem. 2021 Jan 15;296:100295.

Lindahl M, Saarma M, Lindholm P. Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential. Neurobiol Dis. 2017 Jan;97(Pt B):90-102.