We are seeking an accomplished Research Scientist to join the Cancer Genomics Research Team. The Research Scientist is a lab-based role focused on evaluating novel therapeutic targets and generating experimental evidence to support their advancement. This position combines scientific rigor with hands-on expertise to drive cancer genomics research forward. The ideal candidate will have a strong track record in target identification and validation, preferably within the small molecule space.
Key Responsibilities
Laboratory Validation
Plan and execute laboratory experiments to validate and interrogate selected targets using state-of-the-art molecular and cellular techniques, along with undertaking Mechanism of Action studies.
Ensure experimental design meets high standards of reproducibility and scientific integrity.
Data Analysis & Reporting
Analyze and interpret experimental results to inform target and project progression.
Document findings and communicate outcomes effectively in reports and team meetings.
Collaboration
Work closely with bioinformatics, translational research, and other cross-functional teams to integrate data-driven insights into validation and project strategies.
You will work closely with a multidisciplinary team to discover and validate novel cancer targets and help develop first- or best-in-class targets from concept to clinical candidate. This is a unique opportunity to contribute to cutting-edge cancer therapies that can make a real difference for patients.
You will be located in Turku, Finland, and will report to the Head of Cancer Genomics team. The role is full-time and on-site, with a fixed-term contract until the end of July 2027.
What you can expect from us
A chance to work with experienced scientists across Orion’s R&D.
A dynamic and supportive work environment with opportunities for growth.
The opportunity to contribute to innovative therapies that improve patients’ lives.
At Orion Pharma, your work impacts millions of lives around the world. With us, you get to work on challenges that matter and see the difference your work makes every day. We believe our people are the key to our success, which is why we invest in your continuous learning.
Our innovative products are world-class, and we take sustainability and ethics seriously. Rooted in our Nordic heritage, we value teamwork, low hierarchies, and a culture where every voice is heard.
We are builders of well-being and offer jobs with a clear purpose: helping people live their lives to the fullest.
Please visit our website to find further information about our values and Orion as an employer: Working with us
What are we looking for?
Key Qualifications
Fresh Ph.D. (0-2 years of experience) in Molecular Biology, Cancer Genomics, Genetics, or related field OR
Master’s degree with 5-6 years of hands-on laboratory experience in oncology research or functional genomics.
Strong expertise in cell culture, molecular biology, and assay development.
Experience with CRISPR-based gene editing and functional screening.
Experience with RNAi, lentiviral systems, overexpression systems, and knockout cellular models.
Proficiency in cell-based and biochemical assays, imaging, and high-throughput screening.
Ability to design and execute complex experiments independently.
Excellent analytical and communication skills.
Preferred Skills
Familiarity with computational biology tools and pipelines for target discovery.
Knowledge of tumor biology and resistance mechanisms.
Strong ability to interpret large-scale datasets and integrate insights into experimental design.
Prior experience in pharma or biotech environments with drug discovery exposure is a plus.
How to apply and additional information
Please send your application with the latest CV, cover letter, and salary request in English by 10 May 2026. Please note that we will start reviewing applications during the application period.
For additional details, do not hesitate to contact Dr Siddharth De, Head of Cancer Genomics, via email siddharth.de@orionpharma.com.
#LI-ORION
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person.
Your new team
Orion Pharma’s pharmaceutical innovations are created within its R&D organization. We employ around 400 top professionals in the field of drug discovery and development. We work globally: in Espoo and Turku in Finland, in Cambridge and Nottingham in England and in Cambridge, MA, USA. Orion R&D and the Innovative Medicines business division are dedicated to making a transformation to become a global player in the pain and oncology therapy areas.
Cancer Genomics Research Group, is one of three scientific units within Oncology Research, a division of Orion’s R&D Organization. Our team is dedicated to the discovery, validation and targeting of therapeutic targets (utilizing small molecule focused modalities), leveraging omics technologies alongside a broad array of biophysical, biochemical, molecular, cellular, and in vivo methods. We strive to develop cutting-edge small molecule therapies with the potential to transform the lives of cancer patients.
University of Helsinki, Faculty of Medicine invites applications for the position of
Doctoral Researcher
in the Cancer Data Science group led by Associate Professor Mariike Kuijjer, at the iCAN Flagship in Digital Precision Cancer Medicine at the Faculty of Medicine, University of Helsinki.
The position is funded through a project by the Sigrid Jusélius Foundation titled “Regulatory determinants of metastatic progression in high-grade serous ovarian cancer.” The ideal starting date is summer or early fall 2026, but this is flexible and can be discussed. The appointment is a full-time position and is made for a period of three years with possible extension depending on future funding.
Our research
The Kuijjer group was established in 2018 at the University of Oslo and expanded to the University of Helsinki in 2025. The group focuses on developing computational and data science approaches to increase our understanding of gene regulation and how rewiring of gene regulatory networks can influence cancer development, progression, and disease heterogeneity. The group’s current projects use network science and artificial intelligence to develop tools that (i) integrate multi-modal data, (ii) model gene regulation at increased genomic and cellular resolution, (iii) refine the analysis of genome-wide regulatory networks. The group applies these tools to study various cancer types, including ovarian cancer. For more information, visit kuijjerlab.org.
About the role
The advertised project aims to identify regulatory determinants of ovarian cancer progression through regulatory network modeling and analysis. The selected candidate will apply and extend network modeling approaches developed in the Kuijjer group to model patient- and cell type-specific gene regulatory networks using bulk and single-cell ovarian cancer data. These networks will be analyzed to define patient-specific regulatory heterogeneity in primary ovarian cancer, identify regulatory rewiring that drives metastatic progression, characterize the regulatory mechanisms modulated by therapeutic pressure, and assess how these programs relate to therapy response. The project will leverage various publicly available datasets as well as data from the in-house Oncosys-OVA study led by our collaborator Prof. Anniina Färkkilä, University of Helsinki. Overall, the project combines methodological development with biological discovery, offering opportunities to contribute both to computational innovation and to mechanistic insights into ovarian cancer progression.
The candidate
We seek a highly motivated candidate with strong computational skills in the field of high-throughput omics data analysis, comparative genomics, functional genomics, or related fields. The candidate is excited about applying computational tools to answer questions in cancer research. They are collaborative and creative, and have strong programming skills dedicated to the analysis of large-scale genomics data. Experience with the analysis of omics data is required for this position. Knowledge of cancer biology is a strong advantage. Experience with high-performance computing, genomic data integration, biological network analysis, and/or gene regulation is desirable, but not required.
The position is open to applicants with a Master’s degree in computational biology, bioinformatics, biostatistics, cancer genomics, network science, or related fields. Candidates who are finishing their Master’s thesis are also welcome to apply. They should mention the expected date of their defense and steps that need to be completed to finish their thesis in the cover letter.
Qualification requirements
Master’s degree in computational biology, bioinformatics, biostatistics, cancer genomics, network science, or a related field. Applicants with a background in biology or (bio)medicine are welcome to apply, provided they have documented expertise in computational biology
Proficiency in programming (such as Python, R, Bash)
Experience with analysis of high-throughput omics data is required
Knowledge of cancer biology is a strong advantage
Experience with genomic data integration, biological network analysis, and/or gene regulation is an advantage
Experience with high-performance computing is desirable
Strong analytical and problem-solving skills
Teamwork skills and the willingness to collaborate, share ideas, and contribute to a multidisciplinary research environment spanning Helsinki and Oslo
Strong communication skills in English, with both written and verbal proficiency
The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.
What we offer
A salary of 2600 – 2800 €/month depending on the candidate’s qualifications
A professional, stimulating working environment
The University of Helsinki also offers comprehensive services to its employees, including occupational health care and health insurance, unemployment and pension fund, a generous holiday package, sports facilities, and opportunities for professional development: https://www.helsinki.fi/en/about-us/careers.
How to apply
Applications should be submitted through the University of Helsinki Recruitment System via the ”Apply now” button.
Internal applicants (i.e., current employees of the University of Helsinki) submit their applications by using the Employee Login button.
The application must include:
A cover letter, stating your motivation, scientific background, documented experience with large-scale genomic analyses, and research interests
A detailed CV with a list of publications and other research output, if applicable
2-3 references (name, institution, e-mail, telephone number, and relation to the candidate)
These should be uploaded in .pdf format. Applicants may also upload their Master’s thesis or other representative research work, if available. Please submit your application through the web-based recruitment system linked in the announcement. Although the recruitment system includes a basic CV, we ask candidates to also include a separate, detailed CV in .pdf format with their application. Applications without a cover letter and/or detailed CV will not be considered further.
The closing date for applications is 31.5.2026.
Inquiries about the position can be directed to Mariike Kuijjer: mariike.kuijjer (at) helsinki.fi.
If you need technical support with the recruitment system or additional information about the application process, please contact HelsinkiUni Help, uni-help (at) helsinki.fi.
We are seeking an accomplished Target Discovery Lead to join our client’s Cancer Genomics Research Team. The Target Discovery Lead drives innovation in cancer genomics by identifying and validating novel therapeutic targets. This role combines strategic thinking, scientific leadership, and cross-functional collaboration to advance high-impact ideas through the discovery pipeline. The ideal candidate will have a strong track record in target identification and validation, preferably within the small molecule space.
Key Responsibilities
Scientific Strategy & Innovation
Monitor emerging trends and breakthroughs in cancer genomics to inspire new target concepts.
Lead ideation sessions and foster a culture of creativity and scientific rigor in target discovery.
Target Identification & Prioritisation
Design and implement strategies for identifying high-potential therapeutic targets in collaboration with bioinformatics and translational research teams.
Evaluate and prioritise target ideas based on biological relevance, feasibility, and clinical impact.
Validation & Advancement
Oversee experimental validation of selected targets, ensuring robust scientific evidence. Develop and conduct complex assays. Analyse and interpret experimental data, synthesise insights, and communicate results effectively in internal reviews and external presentations.
Define clear advancement criteria and decision-making frameworks to progress targets through the pipeline.
Leadership & Accountability
Act as the primary owner for target ideation goals, ensuring timely delivery and alignment with organisational strategy.
Collaborate cross-functionally internally and externally to integrate insights from genomics, bioinformatics, and clinical research.
Initiate and manage strategic collaborations with CROs, academic institutions, and industry partners to accelerate target discovery and validation.
You will work closely with a multidisciplinary team to discover and validate novel cancer targets and help develop first- or best-in-class targets from concept to clinical candidate. This is a unique opportunity to contribute to cutting-edge cancer therapies that can make a real difference for patients.
What We Offer
A chance to work with experienced scientists in a dynamic R&D environment.
A supportive workplace with opportunities for growth.
The opportunity to contribute to innovative therapies that improve patients’ lives.
A culture of friendliness, respect, mutual appreciation, and diversity, creating a safe environment to strive for excellence.
Career paths and development opportunities that support innovation and impact on quality of life.
Key Qualifications
Ph.D. in Molecular Biology, Cancer Genomics, Genetics, or related field.
Postdoctoral industry experience in oncology research, target discovery, or drug development.
Proven track record in target identification and validation within cancer biology.
Strong understanding of genomics, bioinformatics, and translational research.
Demonstrated ability to lead teams and drive projects to completion.
Excellent communication and strategic thinking skills.
Experience with CRISPR-based functional genomics and gene-editing technologies.
Proficiency in multi-omics data analysis (genomics, transcriptomics, proteomics), with experience in flow cytometry, advanced microscopy techniques.
Preferred Skills
Familiarity with computational biology tools and pipelines for target discovery.
Knowledge of tumor biology and resistance mechanisms.
Strong ability to interpret large-scale datasets and integrate insights into experimental design.
Prior experience in pharma or biotech environments with drug discovery exposure.
TSP Talent Solutions and our customers are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled)
The DNA sequencing and genomics laboratory / research infrastructure is looking for a RESEARCH INFRASTRUCTURE TECHNICIAN to start preferably before the end of 2025, or as soon as possible. Currently we have 5 full-time technicians working within the group, and we are looking for a new technician to join us and to be trained for NGS processes in the laboratory side using our current machinery. The contract is offered initially for 2 years with the possibility of extension as permanent employment.
The DNA sequencing and genomics laboratory is performing a wide variety of DNA and RNA analytics from RNA-seq to de novo genome projects using state of the art Next generation sequencing (NGS) including Element Biosciences and Illumina short-read and PacBio and ONT long-read approaches. We handle thousands of customer samples yearly using both these approaches.
About you
We are looking for a technician with a suitable degree from university of applied sciences or university, who is precise and good at keeping notes of their work. Previous experience with working with DNA/RNA or in making sequencing libraries would be seen as a definite advantage. An interest in instrumentation and /or robotics is a benefit.
The suitable candidate has computer literacy (Windows, Excel, Word) and an ability to work as a part of a team and positive attitude. The required language proficiency for this position is Finnish and English.
What we offer
The University of Helsinki offers comprehensive services to its employees, including occupational health care, insurance for work-related travel and occupational accidents, sports services at a reduced price, and opportunities for professional development.
The International Staff Services office assists employees from abroad with their transition to work and life in Finland.
The position is available as negotiated, but we hope you could start preferably before the end of 2025. The position is offered initially for a fixed-term of two years, but a possibility for permanent extension may be available after that.
The salary is based on the general collective agreement for Finnish universities. The position will be filled at University support and technical staff demand level MV06 for research infrastructures (RI-technician). Gross salary range is ca. 2,500 – 3,300 €/month, depending on experience and qualifications. A 6-month trial period is applied.
How to apply
Applications are to be sent by 13.11.2025, using the UH recruitment system via the button ”Apply now”. Current employees of the University of Helsinki must submit their applications through SAP Fiori’s Suffeli recruitment portal.
The application should include a short cover letter (max 1 page) describing your expertise and motivation for the position, a CV (max 2 pages), and the names and contact information for at least two references. The documents must be submitted as one single PDF file.
The University of Helsinki welcomes applicants from a variety of genders, linguistic and cultural backgrounds, and minorities.
Contact details
For further inquiries, please contact Research Director Petri Auvinen (petri.auvinen(at)Helsinki.fi) or Laboratory Engineer Martyn James (martyn.james(at)Helsinki.fi).
Institute of Biotechnology BI, a part of Helsinki Institute of Life Science HiLIFE, is an internationally renowned research institute with an inclusive and curiosity-driven working culture. The research activities are carried out in research groups joined into three multidisciplinary research programs. The Institute hosts several shared research infrastructures, including cutting-edge facilities for genomic and transcriptomic sequencing, cryogenic electron microscopy (cryo-EM), light microscopy, and proteomics. For more information, please visit https://www.helsinki.fi/hilife/bi
The University of Oulu is a multidisciplinary, international research university, with about 4000 employees who produce new knowledge based on high-standards research and provide research based education to build a more sustainable, smarter, and more humane world. The University of Oulu community has about 17,000 people in total. Our northern scientific community operates globally and creates conditions for the emergence of innovations.
We are now looking for
A Postdoctoral researcher
who will focus on bioinformatic analyses of genomic data obtained from archaeological finds of domesticated animals.
About the job
You will be working with and supported by a group of enthusiastic researchers in a multidisciplinary project that combines historical, archaeological and genetic methods to study the early history of poultry and horses in Northeastern Europe. This project is also a part of the research of the Wildlife Genomics Research group (https://wildlifegenomics.wordpress.com/). Specifically, you will produce and analyze genomic data obtained from archaeological finds of poultry and horses from the region around the Baltic Sea.
Who are you?
We expect that you have:
A PhD in biology (or a relevant field) obtained no more than ten years ago, and prior experience in bioinformatic analyses of genomic data, and knowledge of population genomics
Demonstrated effective writing skills through high-quality publications, including some international experience and networking
Demonstrated capability to work independently and in collaboration with colleagues.
Fluent in English, both in oral and written communication.
What we offer?
Collaboration with and support from a group of enthusiastic researchers in a multidisciplinary project that combines historical, archaeological and genetic methods to study the early history of poultry and horses in Finland, but still independent work.
You will have the opportunity to develop professionally with the assistance of the experienced research group, including participation in local, national, regional and international meetings and workshops.
This is an in-person position, with the possibility of flexible working hours via well-established practices and agreements and local teleworking.
We have an HR Excellence in Research -quality label, which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
Finland is one of the most livable countries in the world, with a high quality of life, safety, an excellent education system, and a competitive economy. Read more about living in Oulu.
Appointment and salary
The position is fixed-term for 4 years as of 1.9.2025 or as soon as possible thereafter, ending 31.8.2029. The salary will be based on levels 5-6 of the demand level chart for Finnish universities’ university-level teaching and research staff. In addition, a salary component based on personal work performance will be paid (a maximum of 50% of the job-specific component). The starting gross salary will be approximately 3800-4200 € per month, depending on the qualifications. A trial period of 6 months is applied to the position.
How to apply
The applications are submitted through the Oulu University recruitment system online, the latest by 21st August 2025 (https://oulunyliopisto.varbi.com/en/). In the application, the applicant should attach:
Curriculum vitae
Publication list
A short cover letter describing motivation and previous experience in relation to the competences mentioned above
Copies of certificates or diplomas
Contact information of two persons available for recommendations
The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview.
Contact information
If you have any further questions, please contact Docent Laura Kvist (laura.kvist@oulu.fi)
The University of Eastern Finland is inviting applications for a Postdoctoral Researcher position on the Kuopio Campus. The position will be filled for a two-year term from 1 October 2024 onwards (or as agreed) with the option to extend for an additional 1–2-year. Please find more information below and submit your application by 5 August 2024.
Role and salary
The Cardiovascular Genomics Lab (Kaikkonen Lab) at the A.I. Virtanen Institute, University of Eastern Finland is seeking a highly motivated and skilled Postdoctoral Researcher. This position is part of an ERC-funded project entitled SECRET that aims to unravel the complex genetic and gene regulatory mechanisms underlying atherosclerotic cardiovascular disease (ASCVD).
The SECRET project focuses on exploring the functional impacts of specific ASCVD-associated cis-regulatory variants identified in GWAS studies. The project will initially screen how these variants influence gene regulation in key vascular cells—endothelial cells and smooth muscle cells. Following the identification of key regulatory variants, further experiments will manipulate these genes directly using CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) to observe the effects on broader gene expression patterns and cellular responses. The generated data will be used to identify convergences around gene regulatory networks, helping to uncover the mechanisms, functions, and pathways that underlie ASCVD risk.
The position is being offered as a 2-year appointment with a 1-2 year extension option. The position is filled for a fixed-term due to it pertaining to a specific project task. A probationary period is applied to all new members of the staff.
The salary of the position is determined in accordance with the salary system of Finnish universities. The salary comprises two components: a job-related salary element and a personal salary element. In this position, the job requirement level is based on levels 5-6 on the job requirement level chart for teaching and research staff. The personal salary element is 6–50% of the job-related salary element. Depending on the personal salary element, the salary will be approximately 3,500 -4,500 €/month.
Our requirements and expectations
We invite applications from talented individuals who are highly motivated and passionate about making a transformative impact in cardiovascular research.
Requirements
A Ph.D. or equivalent in a field relevant to the proposed project
Research Experience: Demonstrable experience in research, preferably within the field of cardiovascular research, genetics, genomics, biotechnology, molecular biology, bioinformatics or a closely related area.
Skills: Proficiency in high-throughput genomic methods and data analysis, genetic manipulation tools (e.g. CRISPR), and/or mammalian cell culture.
Publications: A strong track record of publications.
Communication: Excellent English communication skills, both written and oral.
Teamwork: Ability to work effectively as part of an interdisciplinary and international team.
Motivation: A passion for scientific research, problem-solving abilities, and a strong desire to contribute to the field of cardiovascular genomics.
Autonomy: Candidates should be capable of independent thought and decision-making, demonstrating an ability to lead projects from conception to completion.
Supervision experience: The candidate will have the opportunity to supervise MSc and PhD students
Expectations
Ability to work effectively as part of an interdisciplinary and international team.
A passion for scientific research, problem-solving abilities, and a strong desire to contribute to the field of cardiovascular genomics.
Your benefits
You will have access to the university’s staff benefits, including
opportunity for flexible multi-location work
extensive occupational health care
broad selection of staff training
staff discount on lunch in our campus restaurants, as well as on a range of other services
affordable sports services and tax-free bike benefit
Please read more in the Work at UEF section on our website.
You will have an opportunity to work in an interesting and meaningful role as part of our international, creative, participatory and inclusive academic community.
Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.
How to apply?
Submit your application by using our electronic application form no later than 5 August 2023 by 24:00 (midnight) Finnish time (UTC+3)
Please note that you must include the following appendices in your application
CV (Template for CV , www-page)
a list of publications (Instructions, www-page)
copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas
motivation letter: A detailed letter explaining your interest in the project, how you believe you can contribute to our objectives, and why you consider yourself a strong fit for the role
Questions?
For further information on the position, please contact Professor Minna Kaikkonen-Määttä, tel. +358 29 445 4156, minna.kaikkonen@uef.fi
For further information on the application procedure, please contact HR Controller Tarja Salmi, tarja.salmi@uef.fi, +358 29 4458220 (out of office
The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 3 090 degree students and about 580 PhD students in the Faculty. The faculty has 800 staff members.
The University of Eastern Finland (UEF) is the most multidisciplinary university in Finland. Our university employs approximately 3,200 employees, and our community includes approximately 16,000 degree students and 16,000 adult education students. Our campuses are located in Joensuu and Kuopio. We represent the world’s cutting edge of research in many fields and produce research-based knowledge, which is made openly available to benefit everyone. Learn more about our university at www.uef.fi/en. Read also about UEF as a working community and employer and the career stories of our employees.
