Yhdistys edistää solubiologian tutkimusta, koulutusta, tiedotusta ja työpaikkojen perustamista solubiologeille harjoittaen koulutus- ja tiedotustoimintaa.
Suomen Solubiologit ry jakaa jälleen kerran joka toinen vuosi jaettavan gradupalkinnon!
Onko sinun pro gradu -työsi tehty solubiologian tms. alalta? Onko se hyväksytty aikavälillä 31.8.2021 – 31.8.2023? Jos vastasit kyllä molempiin kysymyksiin, niin hae gradupalkintoamme – Nimittäin, juuri sinun pro gradu -työsi voi olla palkinnon (200 €) saaja.
Palkinnon arvo on 200€, ja se myönnetään syksyllä järjestettävässä seminaarissa. Gradusta julkaistaan lisäksi lyhennelmä Solubiologi-lehdessä!
Tunnustus myönnetään solubiologian tms. alan tutkimusta edistävälle tutkielmalle, joka on hyväksytty aikavälillä 31.8.2021 – 31.8.2023
Kaikki kilpailuun osallistuvat saavat ilmaisen jäsenyyden vuodelle 2024!
Palkintoa voi hakea, vaikka maisterintutkinto ei olisi vielä valmis. Tutkielma voi olla hyväksytty missä tahansa Suomen yliopistossa
Lähetä pro gradu pdf-tiedostona osoitteeseen suomensolubiologit@gmail.com viimeistään 1.10.2023. Liitä mukaan max. 1 sivun mittainen motivaatiokirje, jossa kerrot, miksi sinun gradusi kuuluisi palkita ja mikä sen merkitys on alan tutkimukselle
Lisätietoja apurahasta ja hakemisesta suomensolubiologit@gmail.com
Eliisa Kekäläinen’s research group “Inborn and acquired immunodeficiencies” at the Translational Immunology Research Program at University of Helsinki, Faculty of Medicine invites applications for the position of
POSTDOCTORAL RESEARCHER
Our research group focuses on the human thymus which produces key immune cells, the T cells. We 1) evaluate and develop methods to better measure thymopoiesis, 2) study how thymopoiesis and the thymus itself is affected by viral infections, and 3) aim to understand how and why certain autoimmune diseases, such as myasthenia gravis, develops. We use thymic tissue samples from both immunologically healthy individuals and patients with cutting edge techniques including thymic organ cultures and different multi-dimensional single-cell methods to dissect the normal and pathological processes in the thymus. We are seeking for a motivated post-doctoral researcher to work on Research Council of Finland – funded project.
Qualifications
Applicants with a doctoral degree and strong background in immunology or other relevant life science fields who are interested in working in an inter-disciplinary environment are particularly encouraged to apply. Applicant must be able to work independently and have good communication skills in English. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.
The person we are looking for has:
effective communication and collaboration skills
proven track record in designing and executing experimental science
motivation and determination to learn (more) immunology
Furthermore, if you have experience with the topics below, we would love to hear about your
supervision experience
working with tissue samples or organoid cultures
experience in flow cytometry, single-cell omics, CRISPR-Cas or immunohistochemistry
What We Offer
The appointment will be initially for two years starting from January 2024 (possibility to start earlier or later if needed). Trial period of six months will be applied. The monthly gross salary will be appr. 3200-3600 € per month depending on the appointee’s qualifications and experience. In addition, University of Helsinki offers comprehensive services to its employees, including occupational health care and opportunities for professional development. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .
We offer you on top of these benefits an opportunity to explore and learn in a team that shares a passion for immunology. The team’s well-being is top priority in our laboratory.
How To Apply
Please submit your application as a single PDF file containing your CV, a publication list where you describe your own role in the publications that you consider the most relevant for the position, and two letters of reference. The application will be submitted through the University’s electronic recruitment system by clicking “Apply now” link. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi. The deadline for applications is 30 October 2023. Applications will be considered on a rolling basis until a suitable candidate is found.
For further information on the position, please contact Eliisa Kekäläinen (eliisa.kekalainen(at) helsinki.fi).
For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk (at) helsinki.fi).
Selected publications from Kekäläinen lab:
Hetemäki I, Kaustio M, Kinnunen M, Heikkilä N, Keskitalo S, Nowlan K, Miettinen S, Sarkkinen J, Glumoff V, Andersson N, Kettunen K, Vanhanen R, Nurmi K, Eklund KK, Dunkel J, Mäyränpää MI, Schlums H, Arstila TP, Kisand K, Bryceson YT, Peterson P, Otava U, Syrjänen J, Saarela J, Varjosalo M, Kekäläinen E. Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells. Sci Immunol. 2021 Nov 26;6(65):eabe3454. doi: 10.1126/sciimmunol.abe3454.
Sarkkinen J, Dunkel J, Tuulasvaara A, Huuskonen A, Atula S, Kekäläinen E, Laakso SM. Ectopic germinal centers in the thymus accurately predict prognosis of myasthenia gravis after thymectomy. Mod Pathol. 2022 Sep;35(9):1168-1174. doi: 10.1038/s41379-022-01070-2.
Kleino I, Nowlan K, Kotimaa J, Kekäläinen E. Optimising protein detection with fixable custom oligo-labelled antibodies for single-cell multi-omics approaches. Biotechnol J. 2022 Jun;17(6):e2100213. doi: 10.1002/biot.202100213.
Nguyen NA, Huang X, Cabrera LE, Pekkarinen PT, Nowlan K, Strandin T, Kantele A, Vapalahti O, Heinonen S, Kekäläinen E. A comprehensive assessment of four whole blood stabilizers for flow-cytometric analysis of leukocyte populations. Cytometry A. 2023 Apr;103(4):313-324. doi: 10.1002/cyto.a.24700. Epub 2022 Nov 1. PMID: 36279192.
Lusila P, Toivonen A, Jarva H, Vettenranta K, Lehtimäki S, Kekäläinen E. FASCIA Method in the Assessment of Lymphocyte Mitogen Responses in the Laboratory Diagnostics of Primary Immunodeficiencies. J Clin Immunol. 2023 Apr;43(3):653-661. doi: 10.1007/s10875-022-01417-z.
The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.
The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.
Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.
We are looking for a skilled postdoctoral fellow with a background in neuroscience and/or human stem cell based neuronal models at the Institute for Molecular Medicine Finland FIMM , Helsinki Institute of Life Science, HiLIFE in the research groups of Professor Aarno Palotie ( Research Group Palotie ) and Dr. Olli Pietiläinen ( Research Group Pietiläinen ). The position is part of a research program that aims to discover biological mechanisms in schizophrenia and related neuropsychiatric disorders. The program bridges multidisciplinary group of researchers in the interface of genetic discoveries and multi-omic molecular biology using cell collections from over 6000 sequenced participants. The project combines state-of-art functional genomics and experimental cell biology approaches in human stem-cell derived neuronal models to discover how genetic risk factors identified in the disorders mediate their causative effects in human cells. The Pietiläinen laboratory is based at the Neuroscience Center and has close links with the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard ( https://www.broadinstitute.org/stanley ). The Pietiläinen group is located at the Meilahti biomedical campus in Helsinki and is closely linked with research groups at the HiLIFE Institute for Molecular Medicine https://www.helsinki.fi/en/hilife-fimm (HiLIFE-FIMM) and the Faculty of Biological and Environmental Sciences https://www.helsinki.fi/en/faculty-of-biological-and-environmental-sciences . HiLIFE-NC offers a inspiring environment to solve fundamental challenges of brain functions as part of the multidisciplinary HiLIFE infrastructure https://www.helsinki.fi/en/helsinki-institute-of-life-science at the university of Helsinki. In Pietiläinen group you will be part of a striving scientific community utilizing state of the art technologies in genomics and cell biology for scientific discoveries of the brain.
Role description:
We are seeking a postdoctoral researcher to work on a multidisciplinary project that utilizes human induce pluripotent stem cells (iPSC) to model cellular processes involved in neuropsychiatric disorders. The primary goal is to use known genetic risk variants to identify quantifiable cellular phenotypes that underlie neuropsychiatric disorders. To this end we apply high-throughput multiple omics approaches such RNA sequencing and proteomics that are complemented by experimental molecular cell biology approaches in the in vitro model systems, including cellular assays and gene editing techniques in isogenic cell lines. We are looking for a person for planning, conducting, and co-supervising molecular biology and cellular experiments in human iPSCs.
Key Requirements
We are looking for a highly motivated and creative person with a primary interest in molecular cell biology using human iPSC derived neuronal models to discover mechanisms in neurological disorders, and to work in multidisciplinary team of clinical, wet lab, and computational scientists. Candidates should have a PhD in neuroscience or molecular and cell biology with experience in iPSC derived neuronal models. We require previous experience and skills in cell culture, molecular cell biology, iPSC models, and neural differentiation. The ideal candidate will have experience in these areas, and an interest in translating genetic discoveries into functional biology. Any previous experience in analysing and processing genomic and omic data is considered an advantage. The position is available from September 2023 onwards, or earlier, if required. It is a two-year fixed-term position, with a possibility of extension. Trial period of 6 months will be applied.
The salary will be based on level 5 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance with the overall starting salary amounting to approximately 3600-4500 EUR per month, depending on the qualifications and previous relevant research experience of the candidate.
Please submit your application via the University of Helsinki Recruitment System by clicking the ‘Apply for the position button’ below. If you need support with the recruitment system, please contact recruitment@helsinki.fi.
Please attach the following documents to your application as a single PDF file:
CV (including publications)
cover letter (maximum 1 page) that details your past experience and motivation
contact details of at least two references
The deadline for applications is September 29th, 2023. Interviews will be conducted either in person or online. For more information on the position, please contact Dr. Olli Pietiläinen (olli.pietilainen@helsinki.fi).
University of Helsinki
The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.
Helsinki Institute of Life Science
Helsinki Institute of Life Science (HiLIFE) is a new institute established in 2017 that supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.
Institute for Molecular Medicine Finland
The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki – a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community
HiLIFE -Neuroscience Center
The Neuroscience Center is an international research unit within Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki, a leading Nordic university with a strong commitment to life science research. The research focus of NC is on translational brain plasticity. We carry out research relevant for the human brain both in health and disease, and during development and aging, by applying versatile approaches and modern technology platforms. NC aims at making fundamental discoveries about brain functions and especially translate research findings into improvements in the treatment, prevention and diagnosis of psychiatric and neurological disorders. The research in NC spans across several scales from stem cell research and molecular neuroscience to systems and cognitive neuroscience in both animal and human models.The research groups of NC conduct research in neuroscience at the highest international level and actively apply the results for the benefit of the society. NC collaborates actively with other units of HiLIFE and faculties of the University of Helsinki, Helsinki University Central Hospital, and Neurocenter Finland.
The University of Eastern Finland is inviting applications for a part time (40 %) Research Director/Senior Researcher position at the Kuopio Campus. The position will be filled for a three-year term from 1 November 2023 onwards (or as agreed). Please find more information below and submit your application by 2 October 2023.
Role and salary
We are seeking talented researchers to develop new treatment strategies and gene therapy approaches to cardiovascular diseases by using preclinical and/or clinical research in cooperation with the Kuopio University Hospital (KYS). Your work will have a significant impact on the field of cardiovascular research and will help us develop new approaches to preventing and treating these devastating diseases. We are looking for passionate and self-driven individuals to contribute to strengthening UEF’s strategic profile in cardiovascular diseases.
As our new Research Director/Senior Researcher, you will be working at the A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences. The position is located in Kuopio, Finland.
Our Cardiovascular Research Community is a world leader in conducting gene therapy trials for the treatment of ischemic cardiovascular diseases, in pre-clinical and translational studies, and in manufacturing GMP-compliant gene medicines. This position is intended to further this research and to have a significant impact on the field of translational medicine that will help us develop effective strategies for personalised prevention, diagnostics, monitoring, and treatment of chronic cardiovascular diseases.
As our new Research Director/Senior Researcher in Cardiovascular Research, you will work as an expert within the Cardiovascular Research Community. The responsibilities will also include the supervision of doctoral dissertations, possibly teaching, and the acquisition of external funding.
The position will be filled for a part-time (40 %) three-year term from 1 November 2023 onwards (or as agreed). The position will be filled for a fixed term due to it pertaining to tasks connected to UEF Multimodal Approaches and Data Analytics in Translational Medicine development. A probationary period is applied to all new members of the staff.
The salary of the position is determined in accordance with the salary system for Finnish universities. The salary comprises two components: a job-related salary element and a personal salary element. In this position, the job -related salary element is €3673.96 – 4235.52 /month, based on levels 6–7 of the job requirement level chart for teaching and research staff. The personal salary element can be a minimum of 6 % and a maximum of 50 % of the above-mentioned sum. Depending on the job-related salary element and the personal salary element, the salary (40 %) will be approximately from €1616 – 2152 /month at the beginning of the employment relationship.
Our requirements and expectations
Requirements
a doctoral degree in a relevant field and a medical degree (licenced to practise medicine in Finland)
a strong track record of research in translational preclinical animal models and/or cardiovascular diseases
excellent/good skills in spoken and written English. English is used as the language of instruction and supervision in this position.
experience in externally funded research projects, an independent approach to conducing research.
Expectations/advantages
Being active in clinical practice
Expertise in viral vectors
Specialization in cardiology
Project management skills
Supervisory and teaching skills necessary for the position
Experience in international research cooperation
Collaboration skills
A positiven attitude
Your benefits
You will have access to the university’s staff benefits, including
opportunity for flexible multi-location work
extensive occupational health care
broad selection of staff training
staff discount on lunch in our campus restaurants, as well as on a range of other services
affordable sports services and tax-free bike benefit
Please read more in the Work at UEF section on our website.
You will have an opportunity to work in an interesting and meaningful role as part of our international, creative, participatory and inclusive academic community.
Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.
How to apply?
Submit your application by using our electronic application form no later than 2 October 2023 by 24:00 (midnight) Finnish time (UTC+3)
Please note that you must include the following appendices in your application
a list of publications (https://www.aka.fi/en/research-funding/apply-for-funding/how-to-apply-for-funding/az-index-of-application-guidelines2/list-of-publications/)
copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas
motivation letter: A detailed letter explaining your interest in the project, how you believe you can contribute to our objectives, and why you consider yourself a strong fit for the role
Names and contact information for 2 referees
Other documents to demonstrate the applicant’s merits for the position.
Questions?
For further information on the position, please contact Professor Seppo Ylä-Herttuala, tel. +358 40 355 2075, seppo.ylaherttuala@uef.fi and Research Director Nihay Laham Karam, tel. +358 29 445 4157, nihay.laham-karam@uef.fi
For further information on the application procedure, please contact HR-secretary Tarja Salmi, tarja.salmi@uef.fi, +358 29 4458220
The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 3 090 degree students and about 580 PhD students in the Faculty. The faculty has 800 staff members.
The University of Eastern Finland, UEF, is one of the most multidisciplinary universities in Finland. We have a staff of 3,200 members, and our academic community comprises around 16,000 degree students. Our campuses are located in Joensuu and in Kuopio. Our research is ranked among the best in the world in several fields. We generate research-based knowledge and make it openly accessible for the benefit of all. To learn more about our university please visit our website at www.uef.fi/en. On our website, you’ll also find information about the university as a work community and as an employer (https://www.uef.fi/en/article/one-university-a-thousand-stories), as well as our employees’ career stories (https://www.uef.fi/en/career-stories).
Uusin Solubiologi-lehti (2/2022) julkaistiin juuri ennen vuoden vaihdetta. Saithan sinäkin jo omasi?
Mukana mm. kuukauden solubiologit Emmi Virtanen ja Anna Dahlström, kaksi aivan mahtavaa tiedeartikkelia sekä tutkijatohtori Elina Mäntylän terveiset Cornellin yliopistosta.
