Valtakunnallinen PET-keskus hakee 1-2 väitöskirjatutkijaa tai projektitutkijaa määräaikaiseen tehtävään alkaen syksyllä 2024 (tarkka aloituspäivä sovittavissa) ja päättyen 31.12.2028.
Haemme tutkijaa hankkeeseemme, jossa kartoitetaan positroniemissiotomografian ja toiminnallisen magneettikuvantamisen avulla aivojen ja muun kehon tunnesilmukoiden toimintaa. Hanketta johtaa prof. Lauri Nummenmaa ja sitä rahoittaa Euroopan tiedeneuvosto (ERC).
Tehtävänkuvaus
Väitöskirjatutkijan / projektitutkijan tehtäviin kuuluu PET- ja MRI tutkimusten tekeminen, tutkimusaineistojen analysoiminen ja niiden raportoiminen. Lisäksi tehtäviin kuuluu laboratorion digitaalisten tietovarantojen ylläpidossa avustaminen.
Etsimämme henkilö
Etsimme henkilöä, joka on kiinnostunut kokeellisesta PET- tai MRI-kuvantamisesta, kognitiivisesta ja affektiivisesta neurotieteestä tai psykiatrisesta kuvantamisesta. Hakijoilta edellytetään maisterin tutkintoa soveltuvalta alalta (esimerkiksi lääketiede, tekniikka, luonnontieteet tai psykologia). Hyvä kirjallinen ja suullinen englannin kielen taito on välttämätön. Etsimällämme henkilöllä on kyky itsenäiseen tutkimustyöhön sekä koehenkilöiden kanssa työskentelemiseen, valmiudet opetella kuvantamisaineistojen käsittelemistä sekä perustiedot tutkimusaineiston tilastollisesta analyysista ja tieteellisestä kirjoittamisesta. Kyky työskennellä suuressa kansainvälisessä tutkimusryhmässä on myös välttämätön.
Lisäksi väitöskirjatutkijalta edellytetään korkeakoulututkinnon suorittamisen yhteydessä tai muutoin osoitettua kykyä ja motivoitumista jatko-opintoihin ja tohtorintutkinnon suorittamiseen tutkimussuunnitelman mukaisesti.
Mikäli tehtävään valittavalla ei ole tohtorintutkinnon opinto-oikeutta tehtävään valittaessa, tehtävä täytetään nimikkeellä projektitutkija.
Tarjoamme
Kilpailukykyisen palkan
Huipputason tutkimusympäristön
Erinomaisen työyhteisön
Monipuoliset ja vaihtelevat työtehtävät
Palkkaus ja koeaika
Palkka määräytyy yliopistojen palkkausjärjestelmän (YPJ) opetus- ja tutkimushenkilöstön vaativuustason OV02 mukaisesti, jolloin tehtäväkohtainen palkka on 2 225,83 €/kk. Tehtäväkohtaisen palkanosan lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa. Kokoaikaisesti työskentelevän väitöskirjatutkijan/projektitutkijan aloituspalkka on työsuhteen alussa noin 2 400-2 600 euroa/kk, riippuen aiemmasta kokemuksesta ja osaamisesta.
Tehtävässä on kuuden (6) kuukauden koeaika.
Hakuohjeet
Toimita hakemuksesi Turun yliopiston sähköisen hakemusjärjestelmän kautta viimeistään 14.11.2024 kello 16.00. Laadi hakemusdokumentit englanniksi.
Hakemukseen tulee liittää:
Motivaatiokirje
Ansioluettelo
Kopio tutkintotodistuksista
Suosituskirjeet nyt avoinna olevaa tehtävää varten kahdelta aikaisemmalta ohjaajalta tai esimieheltä yhteystietoineen
Lisätietoja
Lisätietoja avoimesta tehtävästä antaa prof. Lauri Nummenmaa Turun PET-keskuksessa (latanu@utu.fi).
https://www.oulu.fi/fi/yliopisto/tiedekunnat-ja-yksikot/luonnontieteellinen-tiedekunta/ekologia-ja-genetiikka tehdään monipuolista ja laaja-alaista biologista tutkimusta ja koulutetaan osaajia opetus-, tutkimus- ja asiantuntijatehtäviin. Yksikön tutkimusryhmissä tutkitaan useisiin ekologiaan, genetiikkaan ja molekyylibiologiaan sekä näiden rajapintoihin liittyviä aiheita.
Työtehtävät Yliopisto-opettajan tehtävänä on toimia superomaopettajana kaikille kandivaiheen biologian opiskelijoille koko heidän kanditutkintonsa ajan, sekä kansallisen biologian koulutusyhteistyön koordinaattorina.
Mitä tarjoamme? – Ekologian ja genetiikan yksikössä pääset kehittymään ja jakamaan asiantuntemustasi. – Ison organisaation tarjoamat kehitys- ja uramahdollisuudet. – Merkityksellisen työn ja toimintakulttuurin, jossa sinulla on vapaus työn ja muun elämän yhteensovittamiseen. https://www.oulu.fi/fi/yliopisto/toihin-yliopistoon. – Liikunta-, kulttuuri- ja hyvinvointietuja (ePassi). https://www.oulu.fi/fi/yliopisto/toihin-yliopistoon/henkilostoedut.
Mitä etsimme? Odotamme sinulta:
– Ylempää korkeakoulututkintoa biologian alalta tai ylempää korkeakoulututkintoa ja vähintään 60 opintopistettä yliopistotasoisia biologian opintoja. – Hyviä yhteistyö- ja vuorovaikutustaitoja sekä sujuvaa suullista ja kirjallista suomen ja englannin kielen taitoa.
Lisäksi katsomme eduksi:
– Yliopistopedagoginen tai pedagoginen koulutus – Opinto-ohjaajan koulutus, muu ohjaajakoulutus tai opinnäytetöiden ohjauskokemus – Kokemus verkko-opintojen kehittämisestä ja opetuksesta – Kokemus laajojen verkostojen koordinoinnista – Tuntemus Oulun yliopistosta opiskelu- ja/tai työskentely-ympäristönä
Palkkaus Tehtävä on määräaikainen neljälle vuodelle alkaen 1.1.2025 (tai sopimuksen mukaan).
Tehtävä sijoittuu yliopiston palkkausjärjestelmän opetus- ja tutkimushenkilöstön vaativuustasolle 5. Lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on enintään 50 % tehtäväkohtaisesta palkanosasta. Palkka vastaavissa tehtävissä on tyypillisesti 3700-4000 €/kk. Tehtävässä sovelletaan 6 kuukauden koeaikaa.
Kuinka hakea? Jos kiinnostuit, haethan paikkaa rekrytointijärjestelmän kautta viimeistään 15.11.2024. Liitä mukaan:
– Hakemus, johon liitetään kahden suosittelijan yhteystiedot – CV – Opetusportfolio, joka sisältää seuraavat otsikoidut kohdat: – Opetusfilosofia ja opetusmenetelmät – Opetuskokemus ja opetuksen kehittäminen – Oppimateriaalin tuottaminen – Ammatillinen kehitys opettajana – Opetuksesta saatu palaute (opiskelija-arviot, vertaisarvioit, palkinnot ja hyväksytyt opetusnäytteet) – Tavoitteet ja kehittymissuunnitelmat opettamisessa
Tehtävään parhaiten soveltuvat hakijat kutsutaan haastatteluun etäyhteydellä tai kasvokkain. Opetustaitoa arvioidaan opetusportfolion ja opetusnäytteen perusteella. Tulemme olemaan yhteydessä kaikkiin hakijoihin hakuprosessin aikana.
Tampere University and Tampere University of Applied Sciences create a unique environment for multidisciplinary, inspirational and high-impact research and education. Our university community has its competitive edges in technology, health and society. www.tuni.fi/en .
The Hemato-oncology research group studies the molecular mechanisms underlying childhood acute lymphoblastic leukemia (ALL), aiming to develop novel, mechanism-based targeted therapies. Our approach combines a variety of genomic and molecular analyses, drug screening, patient samples, and disease modeling using both cellular and animal systems, including zebrafish.
The Faculty of Medicine and Health Technology (MET) is committed to high quality research and education in the fields of biomedical engineering, biotechnology, medicine, and health technology. We conduct basic, applied, clinical, and translational research in collaboration with Tampere University Hospital (TAYS). Our existing research areas in health research include biomedical engineering fields from biomaterials and microtechnologies to health data science, cell and molecular biology, with applications in areas such as cancer, cardiovascular and celiac diseases, immunology, and ophthalmology.
Job description
We are looking for a talented and motivated postdoctoral researcher to join a project led by Prof. Olli Lohi. The project, funded by the Jane & Aatos Erkko Foundation, focuses on developing targeted therapies for T-cell acute lymphoblastic leukemia (T-ALL). Our research aims to identify novel and effective combination treatments for T-ALL, enhance immunotherapies, and investigate the mechanisms of drug resistance. The work involves the use of cell lines, patient samples, zebrafish models, and a variety of cellular, molecular, and genome-wide assays.
Requirements
We are seeking a versatile and independent researcher with experience and a proven track record-such as published work or a thesis-in a wide range of cellular and molecular biology techniques, including cell culture, drug testing, CRISPR/Cas9 gene editing, and data analysis (e.g., NGS data, R software). Prior experience with leukemia research or zebrafish experimentation would be appreciated.
Applicable doctoral degree in the field, e.g. Molecular and Cellular Biology, Immunology, Cancer Biology, or Genomics
High motivation and a strong research orientation
The ability to work independently, and stay current with relevant literature
Strong interpersonal and networking skills, along with a willingness to mentor junior researchers
Fluency in spoken and written English.
Tampere University is a unique, multidisciplinary, and boldly forward-looking community. Our values are openness, diversity, responsibility, courage, critical thinking, and learner-centredness. We hope that you can embrace these values and promote them in your work.
We offer
The position will be filled for a fixed-term period of three years, starting on 1 January 2025 or as mutually agreed. A trial period of six months applies to all our new employees.
The salary will be based on both the job requirements and the employee’s personal performance in accordance with the Finnish University Salary System. The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff). A typical starting salary of Postdoctoral Researcher is around 3500-3800 EUR/month.
We offer a world-class research environment in internationally recognized research groups. We have strong collaborative networks and offer great opportunities for researchers to develop their careers in an international setting. We offer you the opportunity to join our dynamic and innovative international community.
As a member of staff at Tampere University, you will enjoy a range of competitive benefits, such as occupational health care services, flexible work schedule, versatile research infrastructure, modern teaching facilities and a safe and inviting campus area as well as a personal fund to spend on sports and cultural activities in your free time. Please read more about working at Tampere University. You can also find more information about us and working and living Tampere by watching our video: Tampere Higher Education Community – our academic playground.
Finland is among the most stable, free and safe countries in the world, based on prominent ratings by various agencies. Tampere is the largest inland city of Finland, and the city is counted among the major academic hubs in the Nordic countries. Tampere region is the most rapidly growing urban area in Finland and home to a vibrant knowledge-intensive entrepreneurial community. The city is an industrial powerhouse that enjoys a rich cultural scene and a reputation as a centre of Finland’s information society. Tampere is also surrounded by vivid nature with forests and lakes, providing countless opportunities for easy-to-access outdoor adventures and refreshment throughout the year.
Please submit your application through our online recruitment system. The closing date for applications is 4 November 2024 (23:59 EET / UTC +2). Please write your application and all accompanying documents in English and attach them in PDF format.
Applications should include the following documents:
With questions related to the recruitment process, please contact: HR Specialist Lilli Sarasvirta, lilli.sarasvirta@tuni.fi
***
Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fi
Tampereen yliopiston lääketieteen ja terveysteknologian tiedekunnan alla toimivassa hemato-onkologisessa (HemoRes) -tutkimusryhmässä on haettavana tutkijatohtorin määräaikainen tehtävä translationaalisen leukemiatutkimuksen alalta.
Lääketieteen ja terveysteknologian tiedekuntamme on monialainen biolääketieteen tekniikan, bioteknologian, lääketieteen ja terveysteknologian tutkimuksen ja opetuksen korkeatasoinen yksikkö. Teemme kansainvälisesti merkittävää perus- ja soveltavaa tutkimusta.
Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta. Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta). Hakuaika tehtävään päättyy 4.11.2024 klo 23.59.
FIMM is currently seeking a MSCA Doctoral Researcher for spatial multiplexed immunofluorescence profiling of metastases of different cancer types
in a team led by Dr. Teijo Pellinen
We are seeking a highly motivated Doctoral Researcher for a fully funded, 4-year research position in multiplexed immunofluorescence profiling of metastases from various cancer types. This project, part of the Mac4Me consortium, involves advanced tissue imaging and computational analysis to study immune-tumor cell interactions in clinical samples, including brain, bone, and liver metastases. You will work closely with Genevia Technologies Oy (Finland) and The Norwegian Radium Hospital (Norway) to integrate imaging data with multi-omics datasets using cutting-edge AI tools.
This position is part of the European Union’s Horizon Europe MSCA Doctoral Network programme, which focuses on identifying new immunotherapy targets through innovative research on tumor-immune system interactions. The Mac4Me network provides a unique training environment, combining expertise from 18 academic and industry partners across Europe. Successful candidates will benefit from interdisciplinary training, research visits, and opportunities for skill development in fields ranging from systems biology to AI-driven cancer research.
Work tasks As a Doctoral Researcher in Dr. Teijo Pellinen’s team, you will apply innovative multiplexed immunofluorescence technology to spatially profile cells and their interactions in intact tumor tissue sections. You will analyze imaging data to uncover clinically relevant patterns by linking the imaging results to patient health records using advanced computational methods. More information on Dr. Pellinen’s work can be found here (Teijo Pellinen – University of Helsinki).
Key objectives of this PhD project include: 1. Designing and constructing tissue microarrays (TMAs) with appropriate control tissues, including tumor tissues (prostate cancer, breast cancer, neuroblastoma), metastasis target tissues (bone, liver, brain), and tissues with high immune cell content (e.g., lymph node, appendix). 2. Collecting and organizing clinical and pathological data associated with these tissue samples into a shared clinical database. 3. Developing and optimizing antibody panels for multiplex fluorescence immunohistochemistry (mfIHC). 4. Performing mfIHC on TMAs and analyzing the resulting high-resolution images for single-cell phenotyping.
Expected results This project will provide crucial insights into immune cell behaviour within metastases from prostate cancer, breast cancer, and neuroblastoma. Through single-cell spatial imaging, you will identify the key immune cell subsets and their activation or inhibition states in clinical metastasis samples. The project will also reveal the interactions and proximities between immune cells and tumor cells, offering a deeper understanding of immune responses in metastatic environments.
The imaging data will be systematically indexed and integrated with clinical datasets. You will collaborate with partners from Genevia Technologies Oy and The Norwegian Radium Hospital to merge your results with additional multi-omics data. These analyses will contribute to identifying new immune targets and potential therapeutic approaches for cancer treatment.
The Doctoral Researcher will be based at the Institute for Molecular Medicine Finland (FIMM), University of Helsinki, and work within a vibrant multidisciplinary team embedded in the wider context of Dr. Olli Kallioniemi’s Precision Systems Medicine group at the University of Helsinki (Precision systems medicine | University of Helsinki).
Opportunities for professional development include attending relevant University of Helsinki courses, presenting your findings at national and international conferences, and conducting research visits to other partners in the Mac4Me Doctoral Network.
Eligibility criteria To be eligible for this position, you must meet the following criteria: • Transnational mobility: At the time of recruitment, you must not have resided or carried out your main activity (work, studies, etc.) in Finland for more than 12 months in the 3 years immediately prior to your start date. • Early-Stage Researchers (ESRs): You must have less than 4 years of research experience since completing your first MSc degree and must not have been awarded a doctoral degree at the time of recruitment. • English proficiency: You must have a strong command of the English language, demonstrated through a recognized English proficiency certificate.
Please ensure that you meet all these criteria before applying.
Qualifications
The ideal candidate will have:
MSc degree in a relevant field such as molecular biology, biochemistry, biotechnology, bioengineering, computer science, biostatistics, bioinformatics, biomathematics, systems biology, biomedical sciences, or a closely related discipline. Strong analytical and communication skills, including proficiency in scientific writing and confident interpersonal communication. Experience in bioinformatics or large-scale omics data analysis, including familiarity with commonly used tools and methods. Programming skills (e.g., Python, R) are considered an advantage. Knowledge of cancer research, preclinical model systems, and image analysis techniques is beneficial but not mandatory.
We are seeking a motivated and independent researcher who is eager to learn new skills and contribute to a multidisciplinary project at the intersection of cancer biology, immunology, and data science.
Personal qualities We are looking for a candidate who possesses the following personal attributes: • Eagerness to learn and develop new skills across multidisciplinary fields. • Ability to work both independently and as part of a collaborative team. • Problem-solving mindset with a proactive and solution-oriented approach. • Strong communication skills, especially when working within a multidisciplinary team. • Commitment to meeting deadlines and delivering high-quality results. We offer • A dynamic and inspiring work environment with access to cutting-edge technology and a vibrant, multidisciplinary research community. • Flexible working hours and regular, personalized supervision to support your professional development. • Access to unique datasets and cutting-edge methodologies in cancer research, molecular pathology, and image analysis. • Competitive salary with yearly wage agreements in accordance with Finnish university guidelines. • Comprehensive benefits including pension fund membership and insurance coverage. • Opportunities for career development, including attending relevant courses, presenting at national and international conferences, and research visits to partner institutions across Europe. • Work-life balance in a supportive and diverse working culture, aligned with the Nordic approach to well-being.
To apply, please submit the application through the University of Helsinki electronic recruitment system by clicking on Apply for job.
Please apply no later than 22nd of November 2024
The employment may begin as soon as possible or as agreed.
The Institute for Molecular Medicine Finland (FIMM) is an international research institute focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki FIMM integrates molecular medicine research, technology centre and biobanking infrastructures under one roof, promoting translational research in grand challenge projects, specifically, the impact of genome information from the Finnish population in personalised health and medicine, individualised cancer medicine, and digital molecular medicine. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.
Hae mukaan ammattitaitoiseen ja Eloisaan joukkoomme!
Etelä-Savon hyvinvointialue Eloisa hakee erikoistuvaa sairaalasolubiologia määräaikaiseen virkaan patologian yksikköön ajalle 7.1.2025 – 31.12.2026 tai sopimuksen mukaan.
Uudistuva patologian yksikkömme hakee nyt tiimiinsä erikoistuvaa sairaalabiologia. Yksikkö koostuu kahdesta laboratoriosta, Mikkelin ja Savonlinnan laboratorioista. Erikoistuvan toimi on määräaikainen. Osa-aikainen työ ja osittainen etätyömahdollisuus ovat neuvoteltavissa. Patologian yksikössä työskentelet osana moniammatillista tiimiä ja vastaat yhdessä ylilääkärin kanssa diagnostiikan laadusta ja laboratorion toiminnasta. Toivomme sinulta kykyä työskennellä tiimissä, oma-aloitteisuutta, halua kehittää osaamistasi ja hyviä vuorovaikutustaitoja.
Eloisa tarjoaa yli 60 päivää kestäviin työsuhteisiin etua käytettäväksi liikuntaan, kulttuuriin ja hyvinvointiin sekä kahvit, teet ja kaakaot työpaikalla. Haluamme, että viihdyt ja voit meillä hyvin.
Kelpoisuusvaatimuksena on soveltuva ylempi korkeakoulututkinto, esimerkiksi biologian, biokemian tai molekyylibiologian alalta. Aikaisempi kokemus sairaalabiologin tehtävistä tai patologian yksikössä työskentelystä katsotaan eduksi. Ennen valinnan vahvistamista valitun tulee esittää terveydentilaa koskeva selvitys. Palvelussuhteessa noudatetaan koeaikaa.
Eliisa Kekäläinen’s research group at Translational Immunology Research Program (University of Helsinki, Helsinki, Finland) is looking for post-doctoral researchers or PhD candidates to a new European Research Council – funded project called ProtecTHY.
If you are interested in the human thymus, thymic involution, and hematopoietic stem cell transplantation, please do not hesitate to apply! We offer an exciting opportunity to develop your career in a young and ambitious team using cutting-edge multi-omics methods with human tissue samples. We will for example set up and use the IBEX tissue-imaging method to visualize the thymic microanatomy in detail. We also work closely with virologists, so the project is very much interdisciplinary. Both wetlab and drylab oriented people are welcome to apply. You do not need to be an immunologist to join our team – please follow the link to see what kind of experience within life sciences would be beneficial, what we offer, and apply for the post-doc positions:
We are looking for a Doctoral Researcher at the Department of Biological and Environmental Science, University of Jyväskylä to join the ’Optogenetic Modules’ group of Heikki Takala. The fully funded position for three years will start on 2 January 2025 or as agreed.
Project description
The group of Heikki Takala studies photoreceptor proteins, especially red light-sensing phytochromes, with a special focus on their application for optogenetics.
We are seeking a highly motivated person to develop and apply phytochrome-based optogenetic tools in breast cancer cell models in a PhD project entitled ”Red light sensing optogenetic tools and their application for cancer therapy”. Phytochromes are photoreceptor proteins that respond to red/far-red light. To study these responses and apply them to optogenetics in this project, activity assays in bacterial and mammalian cells, as well as biochemical assays with purified protein, will be utilized. The project will develop optogenetic tools that enable red light-induced apoptosis of breast cancer cells (Fig. 1). These tools will be assayed in 2D and 3D cell models for their therapeutic applicability. The project will provide diverse training and experience in the fields of cell and molecular biology, photoreceptor research, and optogenetics.
Figure 1. The project aims to generate tools for red light-induced
apoptosis of cancer cells.
Qualifications
Applicants must have a Master’s degree, or be about to obtain a Master’s degree, in cell and molecular biology, biochemistry, or other relevant discipline. Ideal candidates should have a strong interest in cancer cell models, photoreceptor research, and optogenetics. Preliminary experience with molecular cloning and mammalian cell cultures is considered highly advantageous. A commitment to accuracy and responsible conduct of research is essential. We require strong motivation to write a PhD thesis, excellent collaboration skills, good oral and written English language skills, and ability to work independently in the laboratory.
The duties, qualification requirements and language skills of a Doctoral Researcher are stipulated by the University of Jyväskylä Regulations and language skills guidelines. The MSc degree required for the position must have been completed before starting the position. Doctoral Researcher needs to be also enrolled in the doctoral programme which can be applied from the Faculty of Mathematics and Science after selection for the position.
We offer
Funding for 3 years in the doctoral program of the University of Jyväskylä.
Supervision in all aspects of the work, a highly skilled project team and possibility to join workshops to improve specific skills in e.g. bioinformatics, data analysis.
International, enthusiastic working environment (working language is English) and a large collaborator network
Excellent research infrastructure at Jyväskylä and state-of-the-art scientific equipment, software, access to journals and scientific databases.
Resources for travel to conferences or workshops abroad.
The position will be based at the University of Jyväskylä, where the student will join the PhD programme in Biological and Environmental Science. At the University of Jyväskylä, you are a recognized member of our community with an ample opportunity to be drawn into international research. You get to participate in our international and multidisciplinary community, where everybody’s welfare is essential. You will work in an inspiring and lively campus area and an environment that supports a healthy and active lifestyle.
Finland has a high standard of living with healthcare, free schooling (also in English), affordable childcare, and good family benefits. The city of Jyväskylä is located in central Finland amidst Finnish lakes and has excellent opportunities for different nature, outdoor, and sports activities. It is a major educational center, whose large student population is responsible for a vibrant cultural scene. To find useful information about the University of Jyväskylä, the City of Jyväskylä, and living in Finland, see the University’s Handbook for international staff and visitors
The initial annual salary will be approximately 30,000 EUR (gross income, including a holiday bonus). With progress of the thesis work, the salary will be revised in accordance with the Collective Agreement of Finnish Universities. The employment starts with a trial period of six months.
How to apply
The application documents that should be included in PDF format:
A two-page long Curriculum vitae, composed according to good scientific practice and considering the template for researcher´s curriculum vitae by The Finnish Advisory Board on Research Integrity and including contact information of two academics who can provide reference letters
Max 1-page motivation letter describing your scientific interests and key motivation for applying for this position
A numbered list of publications, if any
Relevant certificates / diplomas (or date of completion the MSc)
For more information, please contact Academy Research Fellow Heikki Takala, heikki.p.takala@jyu.fi.
Apply between 17 October 2024 and 29 November 2024 23:59 (Europe/Helsinki)
Department of Biological and Environmental Science
The research in the Department of Biological and Environmental Science focuses on three core areas: evolutionary biology, natural resources and environment, and biological nanoscience. The Department building, Ambiotica, is an integral part of the University of Jyväskylä’s Ylistönrinne Mathematics and Science Research Complex, which includes buildings of chemistry, physics and nanoscience. Ambiotica houses high quality laboratories for bioscience and experimental facilities for a wide range of biological and chemical analyses as well as highly motivated laboratory personnel.
The University of Jyväskylä is a human-centered environment of 2,500 experts and 14,500 students. Our goal is to create wisdom and wellbeing for all. JYU’s naturally beautiful campus is located in the heart of the city of Jyväskylä. JYU is the third largest employer in Central Finland.
The application form cannot be saved as draft. However, you have 6 hours to complete your application before the timeout. After submitting you can return to edit your application via the link you receive by email. The application can be edited until the application deadline.
AbbVie’S mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job Description
MIKÄ SINULLE ON TÄRKEINTÄ TYÖSSÄSI?
Meille tärkeintä on aina ihminen. Potilaat, joiden elämänlaatua ja toimintakykyä hoitomme tukevat. Terveydenhuollon ammattilaiset, joille kehitämme lääketieteen huippua edustavia ratkaisuja. Työntekijät, joille tarjoamme merkityksellistä työtä.
AbbVie on osaavien ihmisten yhteisö. Sinä tuot siihen oman arvokkaan panoksesi ja saat tilaisuuden oppia muilta huippuammattilaisilta. Yhteisöllinen yrityskulttuurimme hyväksyy ihmiset yksilöinä ja tukee jokaisen henkilökohtaista kehittymistä.
Onnistumisestamme työyhteisönä kertoo omalta osaltaan sijoittumisemme vuosi vuoden jälkeen parhaiden joukkoon Great Place to Work -tutkimuksessa.
Nyt etsimme Lääketieteelliselle osastollemme sinua asiakaslähtöinen, kokenut
MEDICAL ADVISOR
osaksi Onkologia-tiimiämme.
AbbVien portfolio kasvaa lähitulevaisuudessa uusien onkologisten hoitojen ja käyttöaiheiden myötä. Vastuullasi on perehtyä syvällisesti uusien sairauksien hoitoon, luoda tieteellisiä suhteita uusiin asiakasryhmiin sekä yhteistyössä market accessin kanssa tukea uusien valmisteiden/käyttöaiheiden markkinoille pääsyä.
Vastuullasi on myös tuottaa ja jakaa lääketieteellistä tietoa sekä antaa tieteellistä tukea sekä ulkoisille että sisäisille asiakkaille. Olet tiiviisti yhteydessä asiakkaisiimme ja rakennat kontakteja kyseisen terapia-alueen asiantuntijoihin Suomessa. Toimit yhteistyössä AbbVien tiimin ja terveydenhuollon ammattilaisten kanssa hoitokäytäntöjen parantamiseksi. Varmistat pysyväsi alan tuoreimman tiedon tasalla seuraamalla tieteellisiä julkaisuja sekä osallistumalla kongresseihin ja seminaareihin. Ymmärrät modernin Medical Affairs -työskentelyn pääpiirteet ja olet halukas rakentamaan uusia yhteistyötapoja sekä kehittämään itseäsi ja tiimisi toimintaa alati muuttuvassa toimintaympäristössä. Työskentelet tiiviissä yhteistyössä lääketieteellisen osaston kollegojen, myynti- ja markkinointiosaston sekä Market Accessin kanssa. Raportoit Onkologian ja Hematologian Head of Medical Affairsille.
Qualifications
Odotamme sinulta kokemusta lääkealalta sekä jatkuvasti muuttuvan lääkealan ympäristön tuntemusta. Tehtävä edellyttää lääketieteellistä, luonnontieteellistä tai muuta soveltuvaa ylempää korkeakoulututkintoa sekä vahvaa tieteellistä orientaatiota. Taustaltasi voit olla esimerkiksi lääkäri, proviisori tai biotieteiden asiantuntija.Tieteellinen jatkokoulutus on edellytys tehtävässä menestymiselle.
Aikaisempi tuntemus syöpäsairauksien, erityisesti gynekologisten syöpien hoidosta katsotaan eduksesi. Itsenäisen ja ennakkoluulottoman työskentelyn ohella tarvitset vahvoja vuorovaikutus- ja tiimityöskentelytaitoja sekä valmiutta toimia matriisiorganisaatiossa. Oleellisen tiedon hahmottaminen alan tutkimusartikkeleista ja kirjallisuudesta sekä tiedon selkeä ja ymmärrettävä kommunikointi suomeksi ja englanniksi mahdollistavat työssä menestymisen. Olet kiinnostunut työskentelemään kaupallisessa ympäristössä ja vaikuttamaan potilaiden hoitoon yhteistyössä alan asiantuntijoiden kanssa. Olet parhaimmillasi uusien mahdollisuuksien edessä. Arvostamme myös ymmärrystä suomalaisesta terveydenhuolto- ja rekisteritutkimusympäristöstä. AbbVie tarjoaa innostavan ympäristön, osaamista ja kokemusta RWE-tutkimusten toteuttamisesta sekä mahdollisuuden päästä tuottamaan tutkimustietoa suomalaisista potilaista ja hoitokäytännöistä omalla terapia-alueellasi.
Tarjoamme sinulle laaja-alaisen tehtävän, jossa pääset vaikuttamaan vastuullisella ja merkityksellisellä toimialalla osana menestyvää kansainvälistä yritystä. Tueksesi saat osaavat kollegat ja dynaamisen työyhteisön. Tuemme oppimista ja tarjoamme mahdollisuuden kehittyä ja kehittää osaamista työssäsi.
Additional Information
Kiinnostuitko? Lisätietoja tehtävästä antaa Head of Medical Affairs, Oncology & Hematology Johanna Lammela, puh. 040 9022 478, 15.10. klo 13-15 ja 21.10. klo 13-15. Täytäthän hakemuksesi palkkatoiveella varustettuna sekä CV:si rekrytointijärjestelmäämme viimeistään 23.10.2024 mennessä.
AbbVie on yksi maailman suurimmista lääkeyrityksistä, joka kehittää hoitoja vakaviin sairauksiin, keskittyen immunologisiin ja neurologisiin sairauksiin, onkologiaan ja hematologiaan sekä silmäsairauksiin. Tavoitteemme on parantaa vakavien sairauksien kanssa elävien ihmisten elämänlaatua. Terveydenhuollon ammattilaisille tavoitteenamme on tarjota lääkeluokkansa parhaita tai uusia vaikutusmekanismeja hyödyntäviä ratkaisuja. Haluamme olla lääkealan paras ja kiinnostavin työpaikka. Suomessa työntekijöitä on noin 100 ja toimistomme sijaitsee Pasilassa. Potilaskeskeinen ajattelumme kiteytyy mottoomme ’Aina ihminen’.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
The Medical Scientific Reviewer will support the Medical and Scientific Affairs Team by managing the review processes within the Clinical Sequencing Division (CSD) at Thermo Fisher Scientific. CSD enables Precision Medicine worldwide by delivering effective sequencing solutions for clinical and translational research. As we expand, we support clinical validity studies and generate evidence at both local and global levels. Our goal is to advance molecular diagnostics by improving understanding and communication in this rapidly evolving field. The candidate will play a key role in reviewing scientific and medical documents, ensuring regulatory compliance, handling contracts, and applying oncology expertise to support product development and commercialization.
Key Responsibilities:
Document Review Management: Conduct detailed reviews of scientific, medical, and promotional documents. Ensure consistency, scientific accuracy, and compliance with regulations and guidelines.
Regulatory/Legal Compliance: Act as the point of contact for regulatory and legal teams. Ensure all documents and processes meet requirements (e.g., Sunshine Act, MedTech Code) and comply with diagnostic standards, especially in oncology.
Scientific Expertise (Oncology/Pathology): Apply medical or related field knowledge to review and interpret clinical data, research findings, and diagnostic information. Ensure scientific accuracy and relevance.
Contract Management: Manage contracts by reviewing, negotiating, and ensuring legal and regulatory compliance. Collaborate with internal teams to ensure timely and accurate contract execution related to research, clinical studies, and partnerships.
Quality Assurance: Participate in quality assurance activities. Review protocols, clinical study reports, scientific papers, and contracts for accuracy and adherence to regulatory guidelines.
Process Improvement: Identify areas for improvement in the review process. Develop and implement strategies to boost efficiency while maintaining high-quality standards.
Minimum Requirements/Qualifications:
Bachelor’s or advanced degree in Oncology, Molecular Biology, Biochemistry, or a closely related field.
Experience in medical/scientific review, global regulatory compliance, and contract management within diagnostics or pharmaceuticals.
Strong knowledge of oncology diagnostics and related scientific principles.
Proficiency in contract review and management in a scientific or medical setting.
Ability to thrive in a fast-paced, multidisciplinary environment, with excellent attention to detail.
The HiLIFE – Institute of Biotechnology and the Faculty of Biological and Environmental Sciences at the University of Helsinki are announcing several open positions in three different research groups at the University of Helsinki Viikki campus.
Project Description
Three research groups jointly announce open positions in the following project areas 1) structural virology, 2) structural parasitology in the area of mitochondrial supercomplexes and protein translation 3) antiviral inhibitors of protein secretion and 4) novel molecular glue activators of cell-protective stress pathways. The projects will be housed at the University of Helsinki Viikki campus in the groups of Prof. Sarah Butcher (project #1), Group Leader Dr. Alexander Mühleip (project #2) and Research Director Dr. Ville Paavilainen (projects #3-4). All of the positions will be affiliated with a single research group with more detailed project descriptions below. All of the participating groups are located in the same building with shared group meetings and high synergy, including many ongoing collaborative projects. As a result, the selected people will benefit from a highly synergistic and collaborative environment.
Project #1: Sarah Butcher
The HiLIFE – Institute of Biotechnology and the Faculty of Biological and Environmental Sciences at the University of Helsinki, renowned for its international research excellence, is excited to announce openings for both a postdoctoral researcher and a PhD researcher to join the group of Prof. Sarah Butcher.
Our research focusses on pathogen-host interactions. The successful postdoctoral researcher will join the new Horizon Europe consortium, REFINE to work on West Nile virus entry, inhibition, and prevention, using molecular biology, and structural virology with an emphasis on reconstitution of membrane proteins, virus-antibody interactions, single-particle cryo-EM and image reconstruction. The successful PhD researcher will join the new COMBAT VIRUS project funded by the Jane and Aatos Erkko Foundation, to work on vaccine development for picornaviruses and characterisation of antiviral molecules. The work will involve primarily single particle cryoEM and image reconstruction. We lead the University of Helsinki cryoEM facility and will give training on all of the relevant techniques, using the in-house 200-kV Talos Arctica microscope fitted with a Falcon 4i camera. Computational resources are provided by the national supercomputer center.
About You
you are an ambitious, goal-oriented, team player, motivated to tackle challenging new projects
you are trained in structural biology and virology
a background in protein or virus purification is desirable
commitment to scientific excellence as demonstrated by a strong publication record
excellent command of English to fit into our international group
strong communication, social, and time management skills
What We Offer
a fixed-term 4-year position with a 6-month trial period (PhD position open immediately until filled, postdoctoral position open from March 2025)
a collaborative, innovative and inclusive work environment
performance-related salary (job demands level 2-4 for PhD researcher, level 5 for postdoctoral researcher), 5-7 weeks of annual leave, flexible working hours
financial support with Finnish visa and residency permits, if applicable
occupational health care, access to high-quality sports facilities and language classes
Project #2: Postdoctoral Researcher in structural mitochondrial biology
The HiLIFE – Institute of Biotechnology at the University of Helsinki, renowned for its international research excellence, is excited to announce an opening for a postdoctoral researcher or PhD graduate student to join the group of Dr. Alexander Mühleip.
Project Description
The research of the group is focused on understanding how protein complexes organise mitochondrial membranes in protozoan parasites and when disrupted by human mitochondrial disorders. The successful applicant will work on the structural and functional characterisation of protein complexes involved in mitochondrial energy conversion and translation in protozoan parasites using protein biochemistry, single-particle cryo-EM and in-situ cryo-electron tomography with subtomogram averaging. Specifically, the project is aimed at visualisation of inner-membrane architecture and characterising parasite-specific modulation of membrane biogenesis. The candidate will also have the opportunity to study the structural basis for inhibition of mitochondrial translation in Toxoplasma gondii in collaboration with leading expert Prof. Lilach Sheiner (University of Glasgow). The project offers the unique opportunity to combine parasitology and mitochondrial biology with state-of-the-art structural biology techniques. The group benefits from in-house availability of a 200-kV Talos Arctica microscope, complemented by access to 300-kV cryo-electron microscopes for data collection at international facilities.
About You
you are ambitious, goal-oriented, collegial and motivated to tackle challenging new projects
prospective PhD and postdoctoral researchers should be in the final stages of their thesis submission) in an area of structural biology
prior experience structural biology is critical, a background in electron cryo-tomography and subtomogram averaging is a strong asset
skills in computational protein structure and cryo-EM data processing are desirable
a background in protein purification is desirable
commitment to scientific excellence as demonstrated by a strong publication record
excellent command of English (working language at the institute)
strong communication, interpersonal, organizational and time management skills
What We Offer
a fixed-term 3-year position with possible extension, expected opening for all positions either late Autumn 2024 or beginning of 2025.
a collaborative, innovative and inclusive work environment
support and mentoring for postdoctoral fellowship applications (EMBO, Marie-Curie etc.)
a competitive salary depending on your qualifications and personal performance, 5-7 weeks of annual holiday leave, flexible working hours
financial support with Finnish visa and residency permits, if applicable
occupational health care and access to high-quality sports facilities
Project #3: Postdoctoral Researcher in structural biology
The HiLIFE – Institute of Biotechnology at the University of Helsinki, renowned for its international research excellence, is excited to announce an opening for a postdoctoral researcher or PhD graduate student to join the group of Dr. Ville Paavilainen.
Project Description
The current research in the group has two directions with recent funding from the European Union and US National Institutes of Health. The overall goal of the group is to understand basic mechanisms of protein biogenesis, particularly within the early secretory pathway and in the membrane of the mammalian endoplasmic reticulum. Ongoing drug discovery efforts to target ER protein biogenesis in a client-selective manner are aimed for diseases such as cancer and inflammatory conditions. Here, one project is to study how client-selective inhibition of secretory protein biogenesis could be pursued as a new antiviral strategy against viruses such as Ebola. In the second project, we aim to develop new small molecule tools to activate specific ER stress responses as a cell-protective strategy with relevance to neurodegenerative conditions, including Parkinson’s and Altzheimer’s diseases. This work involves structural biology and biophysical experiments to characterize molecular glue mechanisms with their target proteins in collaboration with synthetic chemistry partners. Both projects take advantage of state-of-the-art structural biology methods, including cryo-EM and X-ray crystallography, chemical biology approaches as well as biophysical studies. The group benefits from in-house availability of a 200-kV Talos Arctica microscope, complemented by abundant access to 300-kV cryo-electron microscopes for data collection at international facilities as well as modern X-ray sources in-house as well as frequent access to European synchrotron sources as part of a Finnish block allocation group.
About You
you are ambitious, goal-oriented, collegial and motivated to tackle challenging new projects
PhD degree (or be in the final stages of PhD submission) in an area of structural biology, for example using X-ray crystallography or cryo-EM approaches, including atomistic modelling of macromolecules.
Prior experience in computational protein structure analysis
high interest in learning structural biology methods (comprehensive cryo-EM training will be provided)
Experience in protein purification is preferable
commitment to scientific excellence as demonstrated by a strong publication record
excellent command of English (working language at the institute)
strong communication, interpersonal, organizational and time management skills
What We Offer
a fixed-term 3-year position with possible extension
a collaborative, innovative and inclusive work environment
support and mentoring for postdoctoral fellowship applications (EMBO, Marie-Curie etc.)
a competitive salary depending on your qualifications and personal performance, 5-7 weeks of annual holiday leave, flexible working hours
financial support with Finnish visa and residency permits, if applicable
occupational health care and access to high-quality sports facilities
General info
How to apply?
Welcome with your application in English (click the ‘apply’ link), as soon as possible or no later than November 7th, 2024. Please note that applications will be continually reviewed. The position is available immediately or according to mutual agreement. Applications should include a cover letter, CV, and contact details of three references. For further information on the position, please contact the group leaders Prof. Sarah Butcher (sarah.butcher@helsinki.fi), Dr. Alexander Mühleip (alexander.muhleip@helsinki.fi) or Dr. Ville Paavilainen (ville.paavilainen@helsinki.fi).
Further Degree Requirements
Further degree requirement for doctoral researcher position: The appointee must apply, and obtain, the right to pursue a doctoral degree at the University of Helsinki within the probationary period of 6 months: https://www.helsinki.fi/en/admissions-and-education/apply-doctoral-programmes/how-apply-doctoral-education
Further degree requirement for postdoctoral position: The degree requirement must be met by the beginning of the employment.
About The Institute Of Biotechnology, HiLIFE, University Of Helsinki
The Institute of Biotechnology is an independent research institute within the Helsinki Institute of Life Science (HiLIFE) , at the University of Helsinki , Finland, and at the global forefront of life science research with state-of-the-art research core facilities in genomics, biological imaging and structural biology. According to the 2024 Times Higher Education World University survey, the University of Helsinki is ranked among the top 80 universities world-wide in life science research. The University of Helsinki is committed to providing a welcoming environment for international researchers , offering comprehensive services and support for relocating to Finland—a country known for its high quality of life, excellent education system, and robust support for research and innovation.
The University of Helsinki welcomes applicants of any gender and age, linguistic or cultural background, or minority group.
Click this link to read about accessibility and inclusivity at our University.
