Ajankohtaista

Bioin­for­ma­tician / FIMM & iCAN

16.1.2022 | Avoimet työpaikat

https://www2.helsinki.fi/fi/avoimet-tyopaikat/bioinformatician-fimm-ican

The Institute for Molecular Medicine Finland (FIMM) is an international research institute focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki. FIMM integrates molecular medicine research, technology centre and biobanking infrastructures under one roof, promoting translational research in grand challenge projects, specifically, the impact of genome information from the Finnish population in personalised health and medicine, individualised cancer medicine, and digital molecular medicine. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.

FIMM-HiLIFE & iCAN Flagship at the University of Helsinki is currently seeking a

Bioinformatician

to join the Institute for Molecular Medicine Finland – FIMM, the leading precision cancer medicine research unit in Finland, and two iCAN Digital Precision Cancer Medicine projects.

FIMM is a translational institute with a driving mission to perform innovative research on patients and populations – utilizing molecular, genomic and health data – targeted towards understanding drivers of health and disease and delivering improvements to the safety, efficacy and efficiency of healthcare in Finland and beyond.

iCAN is part of the Academy of Finland Flagship Programme and hosted by the University of Helsinki and Helsinki University Hospital. iCAN is an innovative multidisciplinary initiative that brings together some of the world’s leading actors in cancer genomics, translational and clinical cancer research, digital health, information technology, machine learning, patients and business to solve one of the most pressing challenges in healthcare – cancer.

The bioinformatician will be working in two closely related subprojects of iCAN Flagship project in cancer precision medicine of solid tumors, COMPORG (immuno-organoids & urological cancers) and iCAN-PEDI (functional precision medicine of pediatric solid cancers), advancing personalized cancer diagnostics and treatment. Our multidisciplinary teams work closely together with clinicians at the hospitals, and our aim is to integrate the clinical and omics data into an analysis platform to enable the cutting-edge cancer research and robust translation back to the clinics for the patient’s benefit.

We are looking for a bioinformatician with experience in omics data analysis and especially integration with other data, such as clinical data. Our omics data comes from, for example, high throughput drug testing, DNA/RNA sequencing, microscopic imaging, ligandome analysis and other approaches (e.g. single cell sequencing, metabolomics, pharmacogenomics). The candidate will also have to be able to build up a database for the ligandome data.

As a Bioinformatician, depending on your profile and experience, you will have the opportunity to
– Together with the iCAN data team, build the iCAN data analysis platform to enable integration of clinical and research data
– Manage our omics data and to develop computational pipelines to further integrate and analyze molecular profiling and imaging data for digital precision cancer medicine
– Work with large datasets in cloud environment
– Create software tools for clinical translation with the potential of revolutionizing treatment of cancer

Qualifications:
– Master’s degree (and/or PhD) in bioinformatics, computational biology, computer science, or equivalent
– Previous experience with omics data, data science or distributed computing environments is appreciated but not required – yet ability to quickly learn new things is essential
– Programming skills, especially in R and/or Python
– Understanding of database fundamentals
– Excellent oral and written communication skills in English; Finnish skills are not required
– Solution-seeking, proactive and respons

Salary and contract:
We will offer a competitive salary that will be based on previous qualifications, experience and performance in the position as based on the Finnish university salary (YPJ) system. The contract will start immediately and will be offered initially until the end of 2022. It may be extended thereafter. A six-month trial period will be applied.

To apply, please submit the application, together with your CV and salary request, through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications by logging in to the SAP system: https://msap.helsinki.fi. Please apply no later than 31.1.2022.

For further information please visit https://ican.fi or contact Vilja Pietiäinen (vilja.pietiainen@helsinki.fi).

Projektitutkija bioanalytiikan laboratorioon

16.1.2022 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?id=000012500&did=5600&lang=fi&jc=14&nav_from_open_jobs_view_new=true

Turun yliopiston biolääketieteen laitoksen bioanalytiikan laboratorioon haetaan projektitutkijaa vuoden määräaikaiseen tehtävään 1.2.2022 alkaen (tai sopimuksen mukaan mahdollisimman pian).

Bioanalytiikan laboratorio

Bioanalytiikan laboratoriossa kehitetään ja validoidaan analyyttisiä menetelmiä (esim. LC-MS/MS) pienien molekyylien kvantitointiin asiakkaiden tarpeiden mukaisesti. Bioanalytiikan avulla saadaan lisätietoa altistumisesta prekliinisissä tai kliinisissä farmakokineettisissä tutkimuksissa, mutta lisäksi kehitetään menetelmiä biomarkkeri- ja ympäristötutkimuksiin. Laboratorio on GLP-sertifioitu. Bioanalyytikan laboratorio sijaitsee Aurumissa, jossa on opetukseen ja laboratoriotyöskentelyyn täysin uudet ja nykyaikaiset puitteet.

Työtehtävät

Projektitutkijan tehtäviin kuuluu kvantitatiiviset näyteanalyysit. Lisäksi hän osallistuu innovatiivisten LC-MS/MS –menetelmien kehittämiseen moninaisille näytematriiseille. Hän osallistuu käytännön töihin laboratoriossa sekä osallistuu tutkimussuunnitelmien ja tutkimusraporttien kirjoittamiseen. Tehtävä voi soveltua tieteellisen jatkotutkinnon aloittamiseen Turun yliopistossa.

Edellytykset

  • Soveltuva ylempi korkeakoulututkinto (esimerkiksi kemian, biokemian tai elintarvikekemian alalta)
  • Bioanalyyttinen tutkimuskokemus ja -taidot, erityisesti nestekromatografisista ja massaspektrometrisista menetelmistä
  • Microsoft Office -ohjelmien hallinta
  • Oma-aloitteellisuus, hyvät sosiaaliset taidot ja aktiivisuus
  • Organisointikyky ja sopeutumisvalmius muuttuviin/vaihtuviin työtilanteisiin
  • Sujuva suomen- ja englanninkielen taito

Tehtävään voidaan valita myös maisteriopintojen loppuvaiheessa oleva henkilö. Tällöin tehtävänimike on tutkimusavustaja.

Eduksi katsotaan

  • GLP-kokemus tai valmius kouluttautua GLP-ympäristöön
  • Kokemus LC-MS/MS-laitteiden huollosta ja ylläpidosta
  • Kokemus erilaisista näytteenkäsittelytekniikoista

Palkka

Projektitutkijan tehtäväkohtainen palkkaus määräytyy yliopistojen palkkausjärjestelmän opetus- ja tutkimushenkilöstön vaativuustasojen 2-4 mukaisesti (2078,27– 2591,28 €/kk). Tehtäväkohtaisen palkanosan lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on 6 – 50 % tehtäväkohtaisesta palkanosasta. Tutkimusavustajan tehtävässä vaativuustaso on 1, jolloin tehtäväkohtainen palkanosa on 1889,69 €/kk.

Tehtävässä on kuuden (6) kuukauden koeaika.

Hakeminen

Hakemukset tulee jättää viimeistään torstaina 20.1.2022 (klo 23:59) yliopiston sähköisellä hakulomakkeella. Linkki hakulomakkeeseen löytyy osoitteessa www.utu.fi/tyopaikat kyseisen tehtävän tiedoista hakemuksen yläosasta kohdasta ”Täytä hakemus”.

Hakemukseen tulee liittää motivaatiokirje, cv ja tutkintotodistukset. Suosittelijoita, jotka ovat antaneet luvan, että käytät heitä suosittelijoina, pyydetään nimeämään kaksi (2).

Lisätietoja tehtävän sisällöstä voit tiedustella apulaisprofessori Aleksi Torniolta, aleksi.tornio@utu.fi, +358 50 476 5715.

Hakuprosessista lisätietoja antaa henkilöstöasiantuntija Kristiina Nuutila (kristiina.nuutila@utu.fi), +358 503135224 tai henkilöstösihteeri Päivi Aalto, paivi.aalto@utu.fi

Downstream Specialists

16.1.2022 | Avoimet työpaikat

https://www.sympahr.net/public/pq.aspx?623af2a7&lang=en-US

We keep growing and we are now looking for Downstream Specialists to reinforce our Manufacturing team.

Downstream is one of the four Manufacturing Streams. Downstream team focuses on the purification of the drug substance. We use chromatographic and filtration purification methods in our biological manufacturing process. The process itself is run by programmed production equipment.

Your primary responsibilities as Specialist include documentation of GMP operations and performing manufacturing operations hands-on in cleanroom environment according current GMP guidelines. The focus of documentation is on SOPs, deviations, change controls and CAPAs. You will also be the first support contact for the manufacturing operators.

It is an advantage if you already have some experience in GMP-work and/or you have knowledge on quality systems.

You could be the person if..

  • You enjoy the combination of hands-on work and documentation.
  • You produce clear, easily understandable and accurate documentation in English.
  • Your working style is precise and you achieve objectives set to you in a timely manner.
  • You pay attention to details but you also easily manage entities.
  • You want to develop yourself and become an expert in your own field.

In order to succeed, you would need a degree in the field of biotechnology, engineering, biochemistry, chemistry or any other related field of study.

As a person, we would like you to be open-minded towards new challenges and spread good team spirit. You also need to communicate fluently both in written and spoken English.

Our Manufacturing team is working in shifts.

Your employment is permanent and we would like you to start preferably in February. We offer you active and lively work community with highly skilled and experienced personnel in gene therapy manufacturing. Working with us, you are entitled to good employment benefits, such as extensive occupational health-care and we support your physical and cultural free-time activities. We provide you wide initial training and a warm welcome. FinVector is located in vibrant Kuopio, which offers a safe living environment, friendly atmosphere and clean nature.

Apply by 24th January!

For more information, please contact Team Lead Johanna Hiltunen tel. 044 430 4674 or Vesa Huusko tel. 040 736 4399 on Wednesday to Friday during 11:00-15:00.

Yliopisto-opettaja, biolääketiede

16.1.2022 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=16&id=000012282&lang=fi

Haemme lääketieteen laitokselle yliopisto-opettajaa. Työ sijoittuu Kuopion kampukselle ja alkaa 01.06.2022. Lue lisää alta, ja hae viimeistään 31.01.2022. (Hakuajan jatkaminen)

Tehtävä ja palkkaus 

Biolääketieteen yliopisto-opettajan tehtävässä työskentelet lääketieteen laitoksen biolääketieteen yksikössä, Kuopion kampuksella. Laitos kuuluu terveystieteiden tiedekuntaan. Lisätietoja yksikkömme toiminnasta löydät verkkosivuiltamme  https://www.uef.fi/fi/yksikko/biolaaketieteen-yksikko

Yliopisto-opettajan (biolääketiede) tehtäviin kuuluu

  • opetustehtävät biolääketieteen kandidaatti- ja maisterivaiheen koulutuksessa sekä ihmisen biologian opintojaksoilla (kampuksella ja verkkoympäristössä), 
  • biolääketieteen yksikön oppimisympäristön kehittäminen ja toteuttaminen yhteistyössä opettajayhteisön kanssa,
  • tutkinto-opiskelijoiden opinto-ohjaus,
  • opinnäytetöiden ohjaaminen ja tarkastaminen,
  • tutkimustyö biolääketieteen yksikössä sekä
  • hallinnolliset tehtävät yksikkö- ja laitostasolla

Tehtävä täytetään määräajalle 01.06.2022 – 31.05.2026. Määräaikaisuuden perusteena on 2021 toteutunut määräaikainen koulutuslaajennus sekä opetustyön uudelleen organisointi yksikössä. Uuden työntekijän tullessa tehtävään käytetään koeaikaa. 

Tehtävän palkkaus määräytyy yliopistojen opetus- ja tutkimushenkilöstön palkkausjärjestelmän mukaisesti. Palkka koostuu tehtäväkohtaisesta palkanosasta ja henkilökohtaiseen suoriutumiseen perustuvasta palkanosasta. Tässä tehtävässä tehtäväkohtainen palkanosa on vaativuustasoluokittelussa tasoilla 4 – 5 (2591,28 – 3000,49 €). Lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on 6 – 50 % tehtäväkohtaisesta palkanosasta. Henkilökohtaisesta palkanosasta riippuen palkka työsuhteen alkaessa on noin 2850,40 – 3660,60 €/kk.  

Mitä edellytämme ja toivomme sinulta? 

Edellytämme sinulta 

  • työtehtävään soveltuvaa ylempää korkeakoulututkintoa sekä hyvää opetustaitoa,
  • hyvää suomen- ja englanninkielen suullista ja kirjallista taitoa,
  • kokemusta alan yliopisto-opetuksesta,
  • hyviä yhteistyö- ja kommunikointitaitoja,
  • kiinnostusta akateemista uraa kohtaan

Katsomme eduksi 

  • pedagogisen koulutuksen,
  • tutkimusansiot,
  • kiinnostuksen osallistua tutkimustyöhön biolääketieteen yksikössä toimivassa tutkimusryhmässä

Tarjoamme sinulle 

  • mielenkiintoisen ja monipuolisen työtehtävän osana kansainvälistä, luovaa, osallistuvaa ja osallistavaa yliopistoyhteisöä, 
  • mahdollisuuden joustavaan monipaikkatyöhön sekä
  • Itä-Suomen yliopiston henkilöstöedut, joihin kuuluvat muun muassa kattava työterveyshuolto, laaja henkilöstökoulutustarjonta, edulliset kampusravintolalounaat ja Sykettä-liikuntapalvelut  

Hae näin 

Jätä hakemus viimeistään 31.01.2022 sähköisellä hakulomakkeella. 

Huomioi, että hakemukseen tulee liittää mukaan: 

Kysymyksiä? 

Lisätietoja tehtävästä antavat biolääketieteen yksikön johtaja Anitta Mahonen, p. +358 29 445 4243, anitta.mahonen@uef.fi 

Lisätietoja hakemisesta ja hakuprosessista antaa HR-sihteeri Minna Leskinen, p. +358 29 445 4278, minna.k.leskinen@uef.fi. 

A post-doctoral position in the collaborative Academy of Finland -funded crossbar project

7.1.2022 | Avoimet työpaikat

https://www2.helsinki.fi/en/open-positions/a-post-doctoral-position-in-the-collaborative-academy-of-finland-funded-crossbar-project

A POST-DOCTORAL POSITION

is available in the collaborative Academy of Finland -funded CrossBar project at the Universities of Helsinki and Turku, and the National Institute of Health and Welfare (THL). The project PI’s are Associate Professor Tarja Sironen (UH), Adjunct Professor Laura Kakkola (UT) and Research Manager, PhD, Pamela Österlund (THL). The position is offered for a fixed-term position for 3 years (approximately one year in each of the partner institutes).

We seek for a highly motivated and experienced postdoctoral researcher in the field of virology, microbiology, immunology or molecular cell biology to join our international and dynamic consortium. The job description is to plan and execute research on zoonotic viruses with pandemic potential.

The successful candidate:

  • Has strong organizational skills, is solution-oriented and has the ability to analytical thinking
  • Has a PhD degree in a relevant field of life sciences and preferably background in virology
  • Has excellent skills in experimental laboratory work and ability to independently plan and execute the experiments
  • Has previous experience in working in BSL-3 conditions or is willing to be trained for work in such conditions Is a team player with good collaboration and communications skills
  • Has good spoken and written English

The degree requirement must be met by the beginning of the employment.The salary is based on the Finnish collective agreement. The position belongs to the category of teaching and research personnel. The salary is in the range of 3100 – 3600 eur/month.The salary level is based on previous qualifications, experience and personal performance in the position according to the hosting institution. The start date is negotiable, and there is a trial period of six months.

The application, together with the required attachments in PDF format (CV, list of publications), must be written in English and submitted through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) must submit their applications through the SAP HR portal.

A special health examination of the suitability to work in the high containment laboratory is required for the person selected to the position. Also, the selected person, with his or her consent, will be asked for PSC (Personnel Security Clearance) assurance through the National Security Authorities (NSA).

The University of Helsinki welcomes applicants from a variety of genders, linguistic and cultural backgrounds, and minorities.

The deadline for the applications is 15.1.2022.

Further information will be given by email of by phone:

  • Tarja Sironen, tarja.sironen(at)helsinki.fi, +358-50-4471588
  • Laura Kakkola, laura.kakkola(at)utu.fi, +358-50-5747101
  • Pamela Österlund, pamela.osterlund(at)thl.fi, +358-295248351

Postdoctoral Researcher / Project Researcher / Early Stage Researcher (Biomedical Informatics)

14.12.2021 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=16&id=000012134&lang=fi

The University of Eastern Finland is inviting applications for a Postdoctoral Researcher / Project Researcher / Early Stage Researcher (Biomedical Informatics) position in Kuopio. The position will be filled for a two-year term from 1 January 2021 (or as agreed). Please find more information below and submit your application no later than 28 December 2021. (Extended application period)

Role and salary

As our new Postdoctoral, Project or Early Stage Researcher in Biomedical Informatics, you will be working in the research group led by Associate Professor and Academy Research Fellow Vittorio Fortino in the Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, Kuopio Campus.

Our group studies and implements data mining algorithms (including machine learning algorithms) to tackle biomedical questions, such as biomarker and drug discovery. Applicants with profound knowledge of (1) bioinformatics tools to analyse genomics and transcriptomics data; and (2) machine learning algorithms are encouraged to apply.

More details on the research group and research interests can be found at 

The successful candidate will work on a project funded by Jane and Aatos Erkko Foundation. 

https://www.uef.fi/en/article/precision-cancer-medicine-with-machine-learning-and-ai

The position is part of a project aiming to develop machine learning approaches

1)      to identify clinically relevant cancer subtypes from multi-omics datasets (TCGA);

2)      to learn how to match cancer cell lines with cancer subtypes via omics data (TCGA, CCLE, GDSC, and GTEx); and

3)      to discover synergistic (and safer) drug combinations from available pharmacogenomics data (e.g. LINCS 1000).

The position will be filled for a two-year term from 1 January 2021 (or as agreed) due to it pertaining to a specific project.  A probationary period is applied to all new members of the staff.

The salary of the position is determined in accordance with the salary system of the Finnish universities. The salary comprises two components: a job requirement component and a personal performance component. For a Postdoctoral Researcher / Project Researcher, the job requirement component is 3,000.49 €/month, based on level 5 of the job requirement chart for teaching and research staff. For an Early-stage Researcher, the job requirement component is 2,078.27 – 2,591.28 €/month, based on levels 2-4 of the job requirement chart for teaching and research staff. The personal performance component can be between 6-50 % of the above-mentioned sums.

At the beginning, the salary will be 3,180.52 – 3,660.60 € /month, as Postdoctoral / Project Researcher or 2,202.97-2,746.76 € /month as Early-Stage Researcher.

Our requirements and expectations

The appointed researcher will have a central role in implementing and applying machine learning methods for the analysis of large-scale omics data. They will have an inquisitive mindset, a proactive attitude, and the desire to further develop their skills for data science and machine learning.

The successful candidate will:

  • Have a PhD in Bioinformatics, Computational Science or a related discipline for the Postdoctoral/Project Researcher position. If the doctoral degree has been awarded less than five years ago, the post will be one of a Postdoctoral Researcher. If the doctoral degree has been awarded more than five years ago, the post will be one of a Project Researcher. In this context, the 5 years refer to a net period time, which does not include parental leaves, or military service.
  • Have an MSc in Bioinformatics, Biosciences or a related discipline for the Early Stage Researcher position; have completed a suitable higher university degree or an equivalent education abroad which in the country in question would qualify the person for similar academic studies. The candidate shall also be qualified to pursue postgraduate studies at the University of Eastern Finland by enrolling in one of the doctoral programmes of the Faculty of Health Sciences.

Desired knowledge, skills, and abilities that are essential for this position:

  • A solid computational (informatics/computer science/coding) background is required..
  • Solid knowledge of, and practical experience in, bioinformatics is required.
  • Experience of analysis of at least two different types of omics data (e.g. gene expression data, genomic data – GWAS, DNA methylation data, etc.) is required.
  • Programming experience in a relevant programming language (e.g., R and Python) is required.
  • Practical experience of working with machine learning methods is required.
  • Practical experience of working with network analysis is an advantage.
  • Applicants must be able to work independently and in a team.
  • Applicants must have good skills in oral and written English.
  • Previous research experience and ambitions will also count during the evaluation process.

Your benefits

You will have access to the university’s staff benefits, including

  • extensive occupational health care
  • staff discount on lunch in our campus restaurants, as well as on a range of other
    services
  • affordable sports services.

Please read more in the Work at UEF section on our website. https://www.uef.fi/en/university#paragraph-4467

How to apply? 

Submit your application by using our electronic application form no later than 28.12.2021 (by24.00 hours Finnish time).

 Please note that you must include the following appendices in your application:

Questions?

For further information on the position, please contact: Associate Professor Vittorio Fortino, +358 29 445 4197,  vittorio.fortino@uef.fi.

For further information on the application procedure, please contact  Saima-asiatTT@uef.fi

Doctoral student, Faculty of Biochemistry and Molecular Medicine

14.12.2021 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=1&id=000012361&lang=fi

We are now looking for a highly motivated Doctoral Student to join the research group of Daniela Ungureanu to work on a project focused to understand the molecular basis of omental metastasis in ovarian cancer. The research project is carried out under Fibrobesity programme funded by the Academy of Finland, targeting obesity-related fibrotic pathologies.

The faculty and the research group
Applications are invited for a full-time fixed-term doctoral student position for a period of four years in the Disease Networks Unit, at the Faculty of Biochemistry and Molecular Medicine (FBMM). The Cancer Signaling group led by Daniela Ungureanu works on the Wnt-receptor pseudokinases signaling involved in cancer development and the application of functional precision medicine for targeted therapies in cancer. The research project focuses on the role of Wnt-signaling in cancer development such as ovarian cancer, to understand the molecular basis for chemoresistance. The main tasks for the research project include working with mammalian and patient-derived tissue cultures and performing a variety of molecular biology methods.

Selected lab publications:
Karvonen et al., Oncogene 2019, PMID: 30631148; Karvonen et al, Cell Death and Disease, 2020, PMID: 32989221; Sheetz et al., Mol Cell, 2020, PMID: 32619402.

Qualification requirements
The successful candidate for the doctoral student position must possess a Master´s degree in the field of molecular biology, biochemistry or translational cancer research. The candidate should have a strong interest in learning cutting-edge methods related to translational, molecular and biochemistry research. Previous demonstrated research experience in molecular biology and basic bioinformatics skills is considered a significant advantage. The selected candidate should be able to work independently as well as in a group with a drive to excel in research. Fluency in both written and spoken English is required. Most importantly, we expect the candidate to have a strong motivation to conduct high-level research in molecular medicine.

What we offer
We offer a research environment with excellent technological facilities and a motivating and supporting international community at the FBMM, University of Oulu. We can also offer access to state-of-the-art facilities located at Oulu, Finland as well as across Europe for doing cutting edge research in cancer research and precision medicine. You will be working in a highly talented research group supported by an excellent network of collaborators in Finland and abroad. University´s wide variety of support services are at your disposal, allowing you to focus on research work. The position is fixed-term 4-year starting at the earliest date in 2022. A trial period of 6 months is applied in the position.

Salary
The salary will be based on the demand levels 2 – 4 of the salary system of Finnish Universities for teaching and research personnel. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 2,400 – 2,500 € per month.

How to apply

Applications, together with all relevant enclosures, should be submitted using the electronic application form by  January 9, 2022 (23:59 Finnish local time). The application should be written in English and include the following:
1) A motivation letter (max. 2 pages) summarizing applicant’s educational background, professional experience and describing why the applicant is interested in this position.
2) A complete Curriculum vitae (max. 4 pages) preferably in accordance with the guidelines of the Finnish Advisory Board on Research Integrity http://www.tenk.fi/en/template-researchers-curriculum-vitae including a list of publications (if available) and contact information of two referees who may be asked to give a statement on the candidate.
3) Certificates/Diplomas: Scanned copy of the original master´s degree certificate and transcript of records and, when necessary, official translations to Finnish or English.

Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Top candidates will be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.

Further information
For further information, informal enquires can be sent to Daniela Ungureanu by E-mail [daniela.ungureanu(at)helsinki.fi] with a subject line “Regarding doctoral student position”.

3 Doctoral Researchers in Biological and Environmental Science

14.12.2021 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=12&id=000012312&lang=fi&_ga=2.264187274.708827638.1638175590-463969467.1611649046

Applications are invited for three 4-year fully funded PhD positions in Biological and Environmental Sciences at the University of Jyväskylä in Finnish Lakeland

3 DOCTORAL RESEARCHES in BIOLOGICAL AND ENVIRONMENTAL SCIENCE 

starting on August 1st 2022 or as soon as possible thereafter, contract length maximum of four years.

Qualifications we are looking for

The Doctoral Programme in Biological and Environmental Science offers doctoral education in Aquatic Science, Ecology and Evolution Biology, Cell and Molecular Biology and Environmental Science. The selected Doctoral Researcher will be assigned to the appropriate research group in the Department. Read more information about the application and the projects in which the PhD project will be made on the web page ”Open doctoral researcher positions”. 

You are the person we are looking for if you have 

  • A Master’s degree, or are about to obtain a Master’s degree, in a relevant discipline. 
  • Strong interest to the research project applied for.
  • Curiosity and interest in fundamental scientific questions.
  • Ability and motivation to work as part of a team, combined with independence and problem-solving skills.

The duties, qualification requirements and language skills of a Doctoral Researcher are stipulated by the University of Jyväskylä Regulations and language skills guidelines. The MSc degree required for the position must have been completed before starting the position. A good command of English is required. The study right for a postgraduate degree required in the position is applied for from the Faculty of Mathematics and Sciences after selection, unless the applicant already has one. 

What does the University of Jyväskylä offer as an employer?

At the University of Jyväskylä, you are a recognized member of our community with a unique opportunity to influence international research. You get to participate in our international and multidisciplinary community where the welfare of each individual is important. At the University of Jyväskylä, we offer a great and lively campus area with opportunities to maintain an active and healthy lifestyle.

Finland has a high standard of living, with free schooling (also in English), affordable childcare, good family benefits, and healthcare. Jyväskylä is located in central Finland in the Finnish Lake District having excellent opportunities for different nature, outdoor, and sports activities. The city of Jyväskylä is a major educational center with a large student population and a vibrant cultural atmosphere. For more information regarding the University of Jyväskylä, the City of Jyväskylä and living in Finland, see the University’s International Staff Guide.

The selected applicant will be paid a standard Finnish PhD salary. The annual salary for a Doctoral Researcher will be approximately 28,000 EUR (gross income, including holiday bonus). With progress of the thesis work, the salary will be revised in accordance with the Collective Agreement of Finnish Universities. A trial period of six months will be used in the beginning of the employment.

How to apply?

The application documents that should be included in PDF format:

  1. Curriculum vitae including publications and contact information of two academics who can provide reference letters
  2. Motivation letter including a statement of research interests. It should be clearly identified the project which is applied for.
  3. Relevant certificates / diplomas (or the date of completion the MSc)
  4. Other relevant documents
  5. English language test record (case dependent) 

Applicants are kindly asked to submit their applications using the online application form by January 14, 2022. For further details, please contact supervisors mentioned in the web page ”Open doctoral researcher positions”.

Postdoctoral Research Fellow, (Functional RNAomics), 2 positions

14.12.2021 | Avoimet työpaikat

https://tuni.rekrytointi.com/paikat/?o=A_RJ&jgid=1&jid=1210

The Functional RNAomics laboratory at the Faculty of Medicine and Health Technology, Tampere University studies gene regulation via RNA processing. By determining how RNA regulation is orchestrated in different cell types, we aim to crack the cellular RNA code and gain critical insights into how aberrations in the RNA machinery result in genetic disorders and cancer. RNA is emerging as a powerful and easily adaptable therapeutic molecule as exemplified by the rapid development of effective mRNA vaccines but a detailed knowledge of RNA regulation in cells is a prerequisite to realise the full potential of RNA-based therapeutic and diagnostic development. We integrate cell biology approaches with mechanistic studies, global mapping of RNA repertoires, RNA binding protein interactions and proteomics profiles to reveal the functional role of RNA-protein complexes in different cell lineages and in disease.

Job description

We are looking for two post-doctoral researchers on full- or part-time basis:

  1. The postdoctoral researcher in cell and molecular biology will conduct experimental research involving advanced molecular biology techniques including sample preparation for short-read and long-read RNA sequencing, cell and organoid cultures, and various biochemistry methods. The work involves experimental planning, detailed recording of data, data analysis and reporting of results.
  2. The post-doctoral research in bioinformatics will analyse a range of large-scale datasets including short-read RNA sequencing, long-read direct RNA sequencing and proteomics data. The work includes the application of existing data analysis pipelines as well as the development of new computational methods. It also involves experimental planning, detailed recording of data and reporting of results.

Requirements

The positions are mostly intended for recently graduated researchers, so that they may gain further experience and advance their careers. You should have a PhD degree in biochemistry, genetics, molecular biology, bioinformatics/computational biology or a related subject area. We expect a competence to pursue independent scientific work. You should be fluent in spoken and written English and have a solid experience either in (1) cell and molecular biology or (2) computational biology/bioinformatics. Skills in both wet and dry lab research are considered an advantage. 

You should be able to communicate with experimental and computational biologists as a member of a multidisciplinary team. We appreciate experience of studying or working abroad and contacts to international research community. We are looking for versatile and independent researchers with experience in the closely related area of the positions. It is expected that you will be able to contribute to the supervision of M.Sc. and Ph.D. students. Please be prepared to provide a proof of your merits when requested.

Tampere University is a unique, multidisciplinary and boldly forward-looking, evolving community. Our values are equity, openness, diversity, responsibility, courage, critical thinking, erudition bildung, and learner-centredness. We hope that you can embrace these values and promote them in your work.

We offer

The position will be filled for a fixed-term period of 2 years in the first instance. The starting date is 1st February 2022 or as mutually agreed. A trial period of six months applies to all our new employees.

The salary will be based on both the job requirements and the employee’s personal performance in accordance with the Finnish University Salary System. The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff). 

We offer a wide range of staff benefits, such as occupational health care, flexible working hours, excellent sports facilities on campus and several restaurants and cafés on campus with staff discounts. Please read more about working at Tampere University.

We offer a world-class research environment in an internationally recognized research group. We have strong collaborative networks and offer great opportunities for researchers to develop their careers in an international setting.

How to apply

Please submit your application through our online recruitment system. The closing date for applications is 10th December 2021 (at 23.59 EET /UTC+2). Please write your application and all accompanying documents in English and attach them in PDF format.

The closing date for applications has been extended until 20 December, 2021.

Applications should include the following documents:

  • Curriculum Vitae according to TENK guidelines
  • List of publications according to Academy of Finland guidelines
  •  References from two people
  •  Motivation letter (1-2 pages) 
  • Description of your research focus, qualifications, previous research fields and main research achievements (1-2 pages)

For more information, please contact:

Professor, Group Leader Minni Änkö, minna-liisa.anko (at) tuni.fi

***

Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fi 

Functional RNAomics -tutkimusryhmä Tampereen yliopiston Lääketieteen ja terveysteknologian tiedekunnassa tutkii RNA-välitteistä geenien säätelyä. Tutkimuksemme tavoitteena on selvittää, miten RNA-tason säätely toimii eri solutyypeissä. Tarkoituksenamme on ‘murtaa solujen RNA-koodi’ ja siten ymmärtää, mikä RNA-säätelyn rooli on geneetisien sairauksien ja syövän synnyssä. RNA on osoittautunut monimuotoiseksi molekyyliksi, jota voidaan soveltaa erilaisten sairauksien hoidossa tai ehkäisyssä, esimerkkinä hiljattain kehitetyt RNA-rokotteet. Jotta RNA:ta voidaan turvallisesti hyödyntää diagnostiikassa ja hoitomuotona, meidän täytyy kuitenkin ensin selvittää, kuinka RNA-säätely toimii solutasolla. Yhdistämme tutkimuksessamme erilaisia solu- ja molekyylibiologian menetelmiä sekä RNA- ja proteomitason profilointia.

Tehtävänkuvaus

  1. Tutkijatohtori/solu- ja molekyylibiologia: molekyyli- ja solubiologian tutkimuksen suunnitteleminen, laboratoriatehtävät mukaan lukien soluviljely, sekvenointikirjastojen valmistaminen erilaisiin RNA-sekvenointisovelluksiin sekä erilaiset biokemian menetelmät, tulosten analysointi ja raportointi.
  2. Tutkijatohtori/bioinformatiikka: RNA-sekvenointi- ja proteomidatan analysointi käyttäen olemassaolevia menetelmiä, uusien analyysimenetelmien kehittäminen, tulosten reportointi.

Tutkimusryhmän työkieli on englanti, joten sujuva englanninkielen taito on välttämätön. Tutkijatohtorin tehtäviin kuuluu nuorempien tutkijoiden ja opiskelijoiden ohjaus. 

Hakuohjeet

Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta.

Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).

Hakuaika tehtävään päättyy 10.12.2021 klo 23.59.

Hakuaikaa jatkettu 20.12.2021 klo 23.59 asti.

Formulation Scientist or Senior formulation Scientist – Biopharmaceuticals

12.11.2021 | Avoimet työpaikat

https://www.recright.com/careers/en/nanoform-finland-oyj/formulation-scientist-or-senior-formulation-scientist-biopharmaceuticals-618cd62f2ece8ffbd4b94c2b

About Nanoform 

Nanoform is an innovative drug particle engineering and nanotechnology company listed on the Premier-segment of Nasdaq First North Growth Market in Helsinki and Stockholm. Nanoform works together with pharma and biotech partners globally to reduce attrition in clinical trials and enhance their molecules’ formulation performance through its nanoforming services. Leveraging our in-house developed AI engine Starmap® we can also predict which customer molecules show most promise for our technology. Nanoform’s capabilities include GMP manufacturing, and its services span the small to large molecule development space with a focus on solving key issues in drug solubility and bioavailability and on enabling novel drug delivery applications.     

Formulation Scientist or Senior formulation Scientist – Biopharmaceuticals 

With a view of developing our organization further, we are now seeking an experienced Formulation Scientist or Senior Formulation Scientist who shares our ambition to develop break-through products for nanoparticles, to join our formulation team in the Pharmaceutical Development unit. The position is fulltime, and it is focused on formulation development for biological compounds (peptides/proteins). The position includes laboratory work. The scientist reports to the Director of Pharmaceutical Development. The location for the job is in our facilities in Helsinki, Finland. The seniority of the applicant will be reviewed during the recruitment process.   

  You will be responsible for  

  • Design and develop formulations and processes for drug products for large molecules for R&D purposes as well as for preclinical and clinical trials
  • Plan, coordinate and ensure timely execution of realistic protocols and reports for feasibility work and clinical trial materials following  current Good Manufacturing Practices and company standards
  • Evaluate product testing results and provide next steps for continued development 
  • Preparation and delivery of reports, SOPs, and technical presentations for both in-house and external parties
  • Participate in relevant meetings/teleconferences with clients
  • Collaborate within cross-functional teams to ensure products are developed to targeted consumer preferences on time and agreed-upon cost targets
  • Manage multiple development projects and develop formulations in a timely manner
  • Stays current with recent advances and trends in the drug delivery technology and regulatory policies 
  • Provide support to R&D and QC  
  • Other duties as assigned.

Ideal experience  

  • Demonstrated skill in developing pharmaceutical formulations for peptides and/or proteins 
  • Experience with nanoparticles  
  • Experience with the analytical characterization of large molecule formulations 
  • Knowledge of protein or nucleic acid chemistry, degradation pathways, and stabilization techniques 
  • Knowledge/Experience of Good Laboratory Practices 
  • Knowledge/Experience of regulatory documentation, in particular ICH pharmaceutical guidelines
  • Experience with various delivery routes and manufacturing processes
  • A high degree of professionalism, ethics and integrity  
  • Proficiency in English, both written and spoken, is a prerequisite
  • Experience in the application of QbD concept in design, execution, and interpretation of formulation and process development experiments 
  • Insight into gastrointestinal physiology
  • Familiarity with Intellectual Property (IP).

Required Degree 

Formulation scientist:  

  • Master’s degree in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Biochemistry or related field with at least three years of relevant industry experience 
  • Preferable: PhD degree in Pharmaceutical Sciences, Chemical Engineering, Bioengineering, Biochemistry or related field with relevant industry experience with at least three years of relevant industry experience. 

Senior formulation scientist:  

  • PhD degree in Pharmaceutical Sciences, Chemical Engineering, or related field with at least five years of relevant industry experience.   

Personal qualities we are looking for 

  • Strong organizational skills and attention to detail 
  • You are a doer and have an accurate working style 
  • Excellent problem-solving skills 
  • Good team working skills but also capability to work independently 
  • You can work in a high-pressure environment  
  • Strong ability to prioritize, multi-task, and work in an interdisciplinary and evolving environment
  • Good presentation and written/verbal communication skills
  • Handling multiple projects and priorities at the same time in a timely manner
  • Be client and patient conscious, considering quality, safety and project.

What we offer to you 

  • A great team to join with skilled and highly motivated colleagues 
  • Encouraging and forward-looking team spirit 
  • Possibility to take responsibility and grow your competencies 
  • Brand new laboratory facilities with state-of-art equipment 
  • Chance to be a part of a team that invents world-class solutions for the medical/healthcare industry 
  • Extensive learning opportunities 
  • Opportunity to utilize your skills and competencies widely as we continuously create something new 
  • Competitive compensation package with broad employee benefits selection 
  • Possibility to be part of a unique fast-growing company in pharma industry.   

We like challenges and want everyone to enjoy solving them together!   

If you have any questions, please contact Director of Pharmaceutical Development Satu Lakio +358 50 56 16 413 on 19th of Nov, 22nd of Nov or 10th of Dec during office hours (EET) or satu.lakio@nanoform.com where you can also book suitable call time if needed.   

Please send your CV and application to us by 12th of Dec 2021.