Doctoral Researchers forDoctoral Education Pilot in Precision Cancer Medicine (ICANDOC)
The University of Helsinki is currently seeking to fill 236 three-year positions for doctoral researchers. These positions are part of a national initiative in doctoral education and are available within various doctoral education pilots. The appointments are set to commence on August 1, 2024, or on January 1, 2025.
As a doctoral researcher at the University of Helsinki, you will conduct your doctoral research as part of an international scientific community under the guidance of top researchers in your field.
122 of the positions are available in the iCANDOC precision cancer medicine pilot. In iCANDOC you will be part of a thriving research community based on the iCAN flagship aiming for discoveries and improved treatments in the area of digital precision cancer medicine. You will be able to leverage a globally unique ongoing pan-cancer study including thousands of patients and multitude of cutting-edge approaches and technologies in translational and clinical medicine as well as data sciences including AI/machine-learning approaches. The iCANDOC program aims to train professionals with various backgrounds to answer the increasing need of professionals in this area and including clinicians. In addition to outstanding supervisors including global leaders in this field, iCANDOC will benefit from an aligned postdoctoral program providing supervision support. With the help of iCANDOC partners including Helsinki University Hospital HUS as well as representatives of relevant private sector areas the program includes training and secondments enabling networking and linkages with potential future employees.
Candidates with a medical training may be considered for these positions with flexible working arrangement, in order to enable clinical work requiring employment at the hospital and beneficial for the thesis project. Further information on the pages of the national iCANDOC program and from icandoc-info@helsinki.fi .
Qualifications And Responsibilities
We are looking for motivated candidates who have demonstrated their capabilities in previous studies and are committed to completing their doctoral degree within the targeted three-year timeframe. In this position your responsibilities will include conducting research for your dissertation and completing the doctoral degree according to the curriculum of the doctoral program. Additionally, you may be involved in teaching and other duties, accounting for up to 5% of your annual working time at the University of Helsinki.
We Offer:
Opportunity to work in an international, multidisciplinary research community
High-quality research infrastructure and support services
Comprehensive support for initiating and advancing your research
Competitive salary (starting salary typically 2,400–2,800 €/month, depending on the appointees’ qualifications and experience), along with benefits such as healthcare and other employee benefits
Assistance with integration into Finland and the University of Helsinki community
Application Process and Selection Criteria
You may apply through two pathways:
Applicants applying through the first pathway are required to have:
A research plan drawn up in collaboration with the supervisor
Supervision plan drawn up in collaboration with the supervisor
A study right for a doctoral degree awarded no earlier than 1.11.2023 OR a stage of studies that allows the candidate to be awarded a right to study for a doctoral degree during the probationary period, i.e. within six months of the start of employment
Applicants applying through the second pathway are required to have:
An example of a research idea and a related concept paper. Candidates who progress to the next stage of the call will have the opportunity to apply for a supervisor and complete their application with an actual research and supervision plan at a later stage.
A stage of studies that allows the candidate to be awarded a right to study for a doctoral degree during the probationary period, i.e. within six months from the start of employment
The selection process will consider:
Suitability of the research plan to the chosen pilot project
Quality and feasibility of the research plan within the three-year timeframe
Planned connections to the professional world and the significance of the position for the applicant’s career after completing the doctoral degree
Feasibility of completing the dissertation within three years, as demonstrated in the supervision plan
Additionally, we expect from all applicants:
Commitment to three years of intensive and work
Strong motivation and previous evidence of the ability to achieve results and complete the project on schedule
Creativity along with the ability for analytical and conceptual thinking, a determined and independent work approach, collegiality, the ability to engage in constructive collaboration with others, and inspire others
Fluent oral proficiency in English and the ability to write scientific texts in English
The appointed doctoral researchers are expected to reside in Finland, though temporary research visits abroad are possible. If relocating, employment can only begin after arriving in Finland.
In addition, there may be consortium-specific requirements or specifications, which are listed in the application instructions online.
Application Instructions and Deadline
Please review the application instructions carefully and submit your application no later than April 22.
Please note that as part of the selection process, we utilize an online competency assessment for all eligible applicants. Please ensure that you allocate approximately one hour between April 27 and April 29 (EEST) to complete the test.
The University of Helsinki is committed to promoting equality, diversity, and inclusion in all aspects of our operations. We encourage applicants from diverse backgrounds, including different genders, linguistic and cultural backgrounds, and minority groups.
Doctoral Researchers for National Doctoral Education Pilot Based on Immune System (IMMUDOCS)
The University of Helsinki is currently seeking to fill 236 three-year positions for doctoral researchers. These positions are part of a national initiative in doctoral education and are available within various doctoral education pilots. The appointments are set to commence on August 1, 2024, or on January 1, 2025.
As a doctoral researcher at the University of Helsinki, you will conduct your doctoral research as part of an international scientific community under the guidance of top researchers in your field.
This research area focuses on immunology including all types of inflammatory diseases, which are future megatrend in healthcare. They all are driven by aberrant immune responses, and immunological interventions are at the heart of their prevention, diagnosis, and treatment. Healthcare urgently needs specialists who understand these immunological areas.
We are looking for 10 doctoral researchers for 3-year doctoral positions to work in the fields of immunology, immunology-based drug development and/or diagnostics. The research can be basic, translational and/or clinical.
Suitable candidates have a background in biomedicine, medicine, life sciences or other relevant discipline.
More information on this research area
Qualifications And Responsibilities
We are looking for motivated candidates who have demonstrated their capabilities in previous studies and are committed to completing their doctoral degree within the targeted three-year timeframe. Your responsibilities will include conducting research for your dissertation and completing the doctoral degree according to the curriculum of the doctoral program. Additionally, you may be involved in teaching and other duties, accounting for up to 5% of your annual working time.
We Offer:
Opportunity to work in an international, multidisciplinary research community
High-quality research infrastructure and support services
Comprehensive support for initiating and advancing your research
Competitive salary (starting salary typically 2,400–2,800 €/month, depending on the appointees’ qualifications and experience), along with benefits such as healthcare and other employee benefits
Assistance with integration into Finland and the University of Helsinki community
Application Process and Selection Criteria
You may apply through two pathways:
Applicants applying through the first pathway are required to have:
A research plan drawn up in collaboration with the supervisor
Supervision plan drawn up in collaboration with the supervisor
A study right for a doctoral degree awarded no earlier than 1.11.2023 OR a stage of studies that allows the candidate to be awarded a right to study for a doctoral degree during the probationary period, i.e. within six months of the start of employment
Applicants applying through the second pathway are required to have:
An example of a research idea and a related concept paper. Candidates who progress to the next stage of the call will have the opportunity to apply for a supervisor and complete their application with an actual research and supervision plan at a later stage.
A stage of studies that allows the candidate to be awarded a right to study for a doctoral degree during the probationary period, i.e. within six months from the start of employment
The selection process will consider:
Suitability of the research plan to the chosen pilot project
Quality and feasibility of the research plan within the three-year timeframe
Planned connections to the professional world and the significance of the position for the applicant’s career after completing the doctoral degree
Feasibility of completing the dissertation within three years, as demonstrated in the supervision plan
Additionally, we expect from all applicants:
Commitment to three years of intensive and full-time work
Strong motivation and previous evidence of the ability to achieve results and complete the project on schedule
Creativity along with the ability for analytical and conceptual thinking, a determined and independent work approach, collegiality, the ability to engage in constructive collaboration with others, and inspire others
Fluent oral proficiency in English and the ability to write scientific texts in English
The appointed doctoral researchers are expected to reside in Finland, though temporary research visits abroad are possible. If relocating, employment can only begin after arriving in Finland.
In addition, there may be consortium-specific requirements or specifications, which are listed in the application instructions online.
Application Instructions and Deadline
Please review the application instructions carefully and submit your application no later than April 22.
Please note that as part of the selection process, we utilize an online competency assessment for all eligible applicants. Please ensure that you allocate approximately one hour between April 27 and April 29 (EEST) to complete the test.
The University of Helsinki is committed to promoting equality, diversity, and inclusion in all aspects of our operations. We encourage applicants from diverse backgrounds, including different genders, linguistic and cultural backgrounds, and minority groups.
Kiinnostaako sinua ura vahvasti kasvavalla, kehittyvällä ja kansainvälisesti merkittävällä terveysteknologia-alalla? Haluatko olla mukana rakentamassa ratkaisuja ihmisten terveyden ja hyvinvoinnin edistämiseksi? Kasva kysytyksi terveysteknologiaosaajaksi ja löydä uusi työ!
Teknologia on lähempänä terveydenhuoltoa kuin koskaan ja ammattitaitoisista tulevaisuuden healthtech-osaajista on todellinen kysyntä. Vauhdikkaasti kasvavalla alalla uudet teknologiat vaikuttavat palveluihin ja tuotekehitykseen merkittävällä tavalla, mikä luo alalle paljon uusia työpaikkoja. Uudet työt tarvitsevat tekijänsä – oletko sinä etsimämme osaaja?
Kasva kysytyksi healthtech-alan osaajaksi ja löydä uusi työ
Useat Uudenmaan, Varsinais-Suomen sekä Pohjois-Savon alueen yritykset etsivät nyt toteutettavan HealthTech Academy -rekrytoivan koulutusohjelman kautta riveihinsä tulevaisuuden osaajia vauhdittamaan alan kasvutarinaa. Uusia osaajia etsivät mm. DelsiTech, LED Tailor ja Sharkmed.
Rooleja on useita ja haemme osaajia hyvin erilaisiin tehtäviin, kuten tuotekehitykseen (laite, kemia tai ohjelmisto), laadunhallintaan tai tekniskaupallisiin tehtäviin, kuten terveysteknologiatuotteiden myynti- ja markkinointitehtäviin, data-analytiikkarooleihin sekä projektienhallintaan.
Mahdollisuuksia on monia ja tehtäviä on tarjolla niin alalle uusina tuleville tekijöille, alanvaihtajille ja kokeneemmillekin asiantuntijoille, jotka haluavat syventää osaamistaan alan parissa. Rekrytoivat yritykset etsivät avoimiin tehtäviin ennen kaikkea motivoituneita ja oman ammattitaidon kehittämisestä innostuneita uusia osaajia. Sinun ei siis välttämättä tarvitse vielä hakuvaiheessa olla valmis asiantuntija – me autamme ohjelman aikana sinua kasvamaan uuteen tehtävääsi!
Voit olla etsimämme henkilö, mikäli sinulta löytyy taustaa tai kokemusta työn, opintojen tai harrastuneisuuden kautta esimerkiksi jostakin seuraavista osa-alueista:
luonnontieteistä tai bioinformatiikasta
laadunhallinnasta ja -varmistuksesta
laitehuollosta tai sähkö-, mekaniikka-, tai elektroniikkasuunnittelusta
tuotekehityksestä tai projektinvedosta
ohjelmistokehityksestä tai ICT-alasta
hoito-, tutkimus- tai laboratoriotyöstä
myynnistä, markkinoinnista tai tuotehallinnasta
terveysalasta
Uusien osaajien rekrytointi tapahtuu HealthTehch Academy F.E.C-koulutuksen kautta. Ohjelma sisältää laadukasta asiantuntijakoulutusta (noin 30 % ohjelmasta). Pääpaino ohjelman aikana osallistujalla on kasvaa uuteen rooliin yhteistyöyrityksessä työn kautta tapahtuvassa oppimisessa – käytännön työtehtävissä ja projekteissa.
Terveysteknologia-ala on tiukasti säädelty, ja regulaatioiden tunteminen on avainasemassa alan työntekijöillä, oli rooli sitten mikä tahansa. HealthTech Academy tarjoaa katsauksen terveysteknologian regulaatioihin ja auttaa sinua hankkimaan tarvittavat taidot ja tiedot alalla menestymiseen.
Voit hakea ohjelmaan, mikäli olet tällä hetkellä työttömänä työnhakijana, työttömyysuhan alaisena tai pian päättyvässä määräaikaisessa työsuhteessa oleva ja työnhakusi TE-palveluissa on voimassa.
Hae mukaan heti!
Hae mukaan mahdollisimman pian, viimeistään 15.4.2024! Jättämällä hakemuksesi mahdollisimman pian pystymme varmistamaan jouhevan hakuprosessin sekä tukemaan sinua haun aikana.
Etenet hakuprosessissa, kun olet täyttänyt omalta alueeltasi kaksi hakemusta:
Uusimaa:
Täytä TE-toimiston hakulomake.Löydät HealthTech Academy -rekrytoivan koulutusohjelman koulutusnumerolla 720179. Esivalinta koulutukseen tehdään tämän TE-toimiston hakemuksen tietojen perusteella, joten perustele hakemuksesi huolellisesti.
Täytä Sarasen osaamisprofiili. Sarasen osaamisprofiili toimii käyntikorttinasi kaikkiin ohjelman rekrytoiviin yhteistyöyrityksiin, jonka kautta pääset kertomaan taustastasi, osaamisestasi ja motivaatiostasi. Profiilin avulla vähennät työpaikkojen hakuammuntaa ja hakemuksien määrää!
Varsinais-Suomi:
Täytä TE-toimiston hakulomake.Löydät HealthTech Academy -rekrytoivan koulutusohjelman koulutusnumerolla 712223. Esivalinta koulutukseen tehdään tämän TE-toimiston hakemuksen tietojen perusteella, joten perustele hakemuksesi huolellisesti.
Täytä Sarasen osaamisprofiili.Sarasen osaamisprofiili toimii käyntikorttinasi kaikkiin ohjelman rekrytoiviin yhteistyöyrityksiin, jonka kautta pääset kertomaan taustastasi, osaamisestasi ja motivaatiostasi. Profiilin avulla vähennät työpaikkojen hakuammuntaa ja hakemuksien määrää!
Pohjois-Savo:
(Haku avautuu pian!)
Ohjelman toteuttavat tiiviissä yhteistyössä ELY-keskus, TE-palvelut, rekrytoivat yritykset, HealthTech Finland ry ja Saranen.
Pohjois-Savo: Laura Hovi, laura.hovi@saranen.fi tai soittoaikoina (maanantaisin klo 12.30–13.30 & keskiviikkoisin klo 9–10) numerosta 040 673 6381
Ohjelmasta järjestetään TE-live hakijainfotilaisuus maanantaina 8.4. klo 13.
Tervetuloa kuulemaan lisää ohjelmasta! Voit lähettää ennakkoon kysymyksesi TE-liven sivuilla sekä myös esittää kysymyksiäsi koko lähetyksen ajan anonyymisti chatin kautta.
HealthTech Academy -rekrytoivassa koulutusohjelmassa yhdistyvät käytännön työtehtävät sekä terveysteknologia-alan asiantuntijakoulutus ainutlaatuisella tavalla. Ohjelma tarjoaa sinulle aidon mahdollisuuden vaikuttaa uraasi syventämällä omaa ammattiosaamistasi sekä löytää tulevan työpaikkasi.
Koulutuksesta eväät työllistymiseen. Koulutusohjelman tärkeimpänä tavoitteena on työllistää sinut yhteistyöyritykseen 6 kk ohjelman päätteeksi. Tavoitteemme on löytää juuri sinun urakehitystäsi parhaiten tukeva rooli! Luelisää hakuprosessista, usein kysytyistä kysymyksistä ja aiempien osallistujien kokemuksista täältä.
Asiantuntijuus uudelle tasolle. Saat ohjelman aikana laadukasta koulutusta alan johtavilta tekijöiltä n. 25 koulutuspäivän myötä, sekä pääset hyödyntämään oppimaasi uudessa työroolissasi. Lopputuloksena kasvatat oman asiantuntijuutesi uudelle tasolle. Koulutus on osallistujille maksuton ja se toteutetaan toistaiseksi etätoteutuksena.
Ohjelma avaa useita erilaisia urapolkuja. Useat eturivin healthtech-yritykset etsivät riveihinsä uusia osaajia, sillä terveysteknologia-alan osaajista on suuri pula. Yritykset etsivät ohjelman kautta tekijöitä erilaisiin ja eritasoisiin kaupallisiin sekä teknisiin tehtäviin.
Koulutuksen tarkoituksena on työllistää sinut yhteistyöyritykseen ohjelman kautta. Tämä voi tapahtua ohjelman päätteeksi, tai jopa ohjelman aikana. Keskimäärin yli 80% osallistujista rekrytoituu uuteen rooliin koulutusohjelman päätteeksi. Ohjelman ajan olet yritykseen koulutussuhteessa ja yritys ei maksa sen ajalta palkkaa. Koulutuksen aikana saat samaa työttömyysetuutta, kuin työttömänä ollessasi. Saat myös kulukorvausta koulutuspäivien ajalta. Jos koulutukseen osallistumisesta on sovittu työllistymissuunnitelmassasi, voi työttömyyskassa tai Kela maksaa koulutuksen ajalta korotettua työttömyysetuutta. Korotettuun etuuteen liittyvistä tarkemmista edellytyksistä, enimmäisajasta ja muusta saat tietoa työttömyysetuutesi maksajalta. Työ- ja palkkasuhde yrityksen kanssa on tavoitteena ohjelman jälkeen ja palkasta sovitaan siinä kohtaa yrityksen kanssa.
The University of Eastern Finland is inviting applications for a Project Researcher position on the Institute of Biomedicine, Kuopio Campus. The position will be filled for a two-year term from 1 May 2024 (or starting date as agreed). Please find more information below and submit your application by 8 April 2024.
Role and salary
We are seeking a highly motivated and talented Bioinformatician or Computational Biologist (PhD or MSc) interested in a career path as a core facility expert to join the UEF Bioinformatics Center. The goal of the bioinformatics core facility is to contribute to research excellence through standard and customized omics data analysis, as well as to implement innovative machine learning, data integrative and multimodal solutions. The hosting core facility is located in the School of Medicine, Faculty of Health Sciences, on the UEF Kuopio campus. The infrastructure is also part of the Biocenter Finland Bioinformatics Platform.
The Project Researcher will participate in research projects and develop biomedical and multimodal data analysis solutions for UEF Research Communities in cancer, metabolic, cardiovascular, and neurodegenerative diseases. You will join the growing local network of bioinformaticians. Depending on your profile and experience, you will have the opportunity to develop your expertise in multiomics analyses, combining omics and imaging data with clinical data from local cohorts and other resources such as FinnGen. UEF core facilities in single-cell genomics, metabolomics and biomedical imaging will offer opportunities to network with domain experts. You will have access to the local high throughput computational infrastructure of the Bioinformatics Center and the Finnish national computational infrastructure of CSC. The position also offers an opportunity to participate in teaching.
The main responsibilities of the Project Researcher include:
collaborating with biomedical and data analysis experts in research projects,
pre-processing and analysing different types of omics, multiomics or multimodal data, and
developing state-of-the-art workflows.
The position will be filled for a two-year term from 1 May 2024 (or starting date as agreed). The position will be filled for a fixed term due to it pertaining to a specific project tasks. A probationary period is applied to all new members of the staff.
The salary of the position is determined in accordance with the salary system of the Finnish universities. The salary comprises two elements: a job requirement element and a personal performance element. In these positions, the job-related salary element is based on level 5–6 (PhD) and level 3–4 (MSc) of the job requirement level chart, and the personal salary element is 6–50% of the job-related salary element. The estimated monthly salary at the beginning of the employment will be EUR 3.534 – 4.497/month for a PhD and EUR 2.689– 3.330 /month for a MSc.
Our requirements and expectations
We welcome highly motivated applicants with a bioinformatics or data science background and a high interest in biomedical data analysis.
Requirements
The person to be appointed as a Project Researcher must hold a PhD or MSc in bioinformatics, computational biology, data science or a related field. Applicants with a PhD or MSc degree from other fields must demonstrate to have substantial experience in bioinformatics data analysis.
Good understanding of machine learning methods.
Experience in the analysis of at least one of the following data types:
Genome or phenome-wide association
Bulk or single-cell transcriptomics
Bulk or single-cell epigenomics
Proteomics or metabolomics
Strong skills in R programming, Linux shell scripting and Python or other relevant scripting language.
Excellent written and spoken English skills.
Good communication skills as well as a high degree of independence and initiative.
The following will be considered an advantage:
Experience in GWAS, metabolomics, knowledge graphs or other multimodal data analysis.
Experience in the use of containers and version control.
Your benefits
You will have access to the university’s staff benefits, including
opportunity for flexible multi-location work
extensive occupational health care
broad selection of staff training
staff discount on lunch in our campus restaurants, as well as on a range of other services
affordable sports services and tax-free bike benefit
You will have an opportunity to work in an interesting/meaningful/diverse role as part of our international, creative, participatory and inclusive academic community.
Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.
How to apply?
Submit your application by using our electronic application form no later than 8 April 2024 by 24:00 (midnight) Finnish time (UTC+3)
Please note that you must include the following appendices in your application
For further information on the position, please contact Research Manager Virpi Ahola, virpi.ahola@uef.fi, +358-50-5687597 or visit https://bioinformatics.uef.fi
For further information on the application procedure, please contact: Human Resources hrbiomed@uef.fi
The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 3 090 degree students and about 580 PhD students in the Faculty. The faculty has 800 staff members.
The University of Eastern Finland (UEF) is the most multidisciplinary university in Finland. Our university employs approximately 3,200 employees, and our community includes approximately 16,000 degree students and 16,000 adult education students. Our campuses are located in Joensuu and Kuopio. We represent the world’s cutting edge of research in many fields and produce research-based knowledge, which is made openly available to benefit everyone. Learn more about our university at www.uef.fi/en. Read also about UEF as a working community and employer and the career stories of our employees.
We are looking for a highly motivated doctoral researcher to join the 3-year period ImmuDocs Doctoral Education Pilot project “Macrophages and neutrophils in cancer progression”, led by Professor Jyrki Heino, University of Turku.
Project description:
Malignant tumours consist of transformed cancer cells and of numerous other cell types including cancer associated fibroblasts (CAFs), tumour associated macrophages (TAMs), neutrophils, lymphocytes and endothelial cells. All cell types regulate each others’ phenotype and behaviour and cancer progression. Extracellular matrix (ECM) – mainly produced by CAFs – is an important component of the tumour microenvironment. ECM has a major impact on cancer cells, on the efficacy of immunotherapies and finally on the disease outcome.
We have developed new 3D spheroid-based methods to study the interactions of different cell types: human cutaneous squamous cellular carcinoma (cSCC) cells, CAFs and TAMs/neutrophils. Using e.g. mass spectrometry, RNA-sequencing, microscopy and cellular assays for proliferation, phenotype/plasticity and invasion the project aims to unveil the TAM and neutrophil based regulatory mechanisms of invasion and ECM remodelling. Furthermore, our preliminary results have revealed the remarkable plasticity of TAMs. The project aims to find molecular mechanisms used by CAFs and cSCC cells to regulate TAM phenotype.
In our recent paper we showed that the spheroid model can be used to successfully screen potential drug molecules (Siljamäki et al., Oncogene, 2023. PMID: 37864034). In this doctoral project the spheroids containing three different cell types will be used to test the effects of the inhibitors of critical signalling pathways. The model also allows testing of putative drug molecules targeted to macrophages and neutrophils.
Finally, we have recently established a method to combine laser capture microscopy to mass spectrometry and shown that it is possible to get detailed information about e.g. ECM composition in different tumour areas of paraffin embedded SCC tumours and their metastases. This in vivo information is critical for interpretation of the results from in vitro experiments focused on the effects of macrophages and neutrophils on the composition and organization of the ECM.
Are you passionate about the tumor microenvironment, immune evasion and integrative multi-omics in cancer? Join us and experience Finland, the happiest country in the world! In Helsinki, you will find an international dynamic culture combined with an excellent quality of life close to nature and with the cleanest air in the world.
Our research
A postdoctoral position based on the EU funded project SPACE is provided in Anniina Farkkila’s lab (http://farkkilab.org), located at Biomedicum, University of Helsinki, Finland. The lab is part of Research Program for Systems Oncology, Faculty of Medicine, and Helsinki Institute for Life Sciences. We are an interdisciplinary team of clinicians, biologists, bioinformaticians, and data scientists working together to improve the treatment and lives of cancer patients.
The overall goal is to discover how the tumor cells evade the immune system in ovarian cancer, with prospects of leading to major scientific breakthroughs and successful translation of the findings into clinical trials. We aim to integrate genomic profiles (WES, ctDNA, RNAseq), with single-cell and spatial information from spatial genomics, proteomic and transcriptomic data and associate the findings to clinical data using machine learning.
We have collected a unique set of multi-omics, multi-site spatial data from more than 300 patients in the prospective Oncosys-OVA study, including sequencing, imaging and curated clinical data. Our multidisciplinary team has also developed experimental and functional models to validate findings emerging from the data, generating a unique environment to drive scientific discoveries with clinical relevance.
Our lab received a prestigious ERC grant in 2022 and has received steady funding from e.g. the Research Council of Finland, Sigrid Jusélius Foundation, and Cancer Foundation. We also actively collaborate with esteemed research institutes globally, including Harvard Medical School and Netherlands Cancer Institute.
Your mission
You will be expected to bring expertise in computational techniques on single-cell spatial multi-omics and co-mentor doctoral and master’s students.
You will have the opportunity to participate in e.g.:
Single-cell spatial atlas of high-grade serous ovarian cancer. Discovering associations of tumor mutations with single-cell tumor microenvironment using data science and machine learning.
Pixel-based spatial molecular profiling based on imaging datasets. Developing deep learning approaches for automated extraction of features from the tumor micro-environment associated with clinical-molecular profiles.
3D reconstruction of the spatial structures and functional features for diagnostic and prognostic stratification of ovarian cancer patients.
Multimodal data integration from our large genomic, single-cell proteomic and transcriptomic datasets to find clinically meaningful features for precision oncology.
Requirements:
Solid background in bioinformatics or computational biology. Knowledge in machine/deep learning.
Experience working with high-performance computing, containers and packages. Previous experience working with clusters, cloud computing, and virtual machines.
Proficiency in Linux, and proficiency in programming languages such as R, Python, and Matlab (for 3D reconstruction project).
Previous working experiences relevant with image analysis/computer vision or single-cell omics data.
Basic knowledge and interest in cancer biology or immunology are expected.
What we offer:
You will be immersed in the rich interdisciplinary culture of the research program. We offer excellent training and coaching towards an ambitious career.
Our mentality is to maintain a highly collaborative and enthusiastic atmosphere in the Lab and exploit our rich international scientific networks. You will have a chance to expand your research connections.
The research will be highly clinically relevant within the precision oncoloty and immuno-oncological area. Our multidisciplinary approaches have unique prospects of changing your scientific discovery into clinical biomarkers to be tested in prospective trials with direct patient benefit. This postdoc experience will be a solid basis for your next-level career.
A monthly salary and benefits according to the Helsinki University standards will be applied (around 3400-4000€/month). The salary will guarantee a high quality of life in Helsinki.
The position is available as soon as the selected candidate is available. The project initially allows a 2-3 year fixed-term position. A trial period of 6 months will be applied. Salary will depend upon the applicant’s level of skills, knowledge, and abilities and is based on the university salary system.
To apply send in a single PDF
Cover letter including three referees (max 1 page)
CV (max 2 pages)
Publication list
For further information contact anniina.farkkila(at)Helsinki.fi
Tampere University, Finland’s second largest higher education institution, creates a unique environment for multidisciplinary, inspirational and high-impact research and education. Our universities community has its competitive edges in technology, health and society. Read more: www.tuni.fi/en
Faculty of Social Sciences (Psychology) at Tampere University is seeking a motivated Postdoctoral Research Fellow to a Research Council of Finland funded project called “Early Life Intestinal Microbiota and Childhood Mental Health and Cognitive Development”.
The project focuses on the associations between alterations in human gut microbiota and emotional, social, and cognitive development during childhood. Project will also examine the role of gut microbiota as a potential mediator between the environmental factors, such as breastfeeding and maternal prenatal adversities, and child’s psychological development. The project builds mainly on already established Health and Early Life Microbiota (HELMi) birth cohort (NCT03996304) that investigates the drivers and health consequences of the early microbiota development in thousand Finnish children. The project will be conducted in collaboration between Tampere University and University of Helsinki.
The post offers opportunities for personal development as a researcher in an enthusiastic and international group that has a long track record in both developmental psychology and in human microbiota research. The project offers a great opportunity to connect these two areas of research and to network internationally with research groups working on same or related fields.
Job Description
The Postdoctoral Research Fellow will study the associations between variations in human microbiota across early childhood and child’s mental health and cognitive development. The applicant is responsible of data processing and analyses as well as writing high-quality scientific papers. The applicant will also take part in designing and collecting new data. The chosen person has an opportunity to influence on their focus area within the general objectives of the project.
The Postdoctoral Research Fellow is expected to actively elaborate their research and publish in high-quality scientific journals. In addition, they must participate in the research group’s activities, present research results in seminars and scientific conferences as well as take part in writing of grant applications. The person selected for the position is also required to participate in teaching and supervision of PhD studies.
Requirements
The ideal applicant will hold a PhD in Psychology, Bioinformatics, Epidemiology, Biomedicine, Microbiology, or a similar field. Applicant must have excellent statistical skills to analyze independently large and complex biological data using R- or similar statistical environment. Previously acquired knowledge of developmental psychology, human physiology and/or microbiota is considered an advantage. The applicant is required to have the ability to conduct high-quality scientific research. The applicant must also be able to work both independently and collaboratively as part of a larger research group.
The applicant must have excellent written and oral English language skills. Knowledge of Finnish and Swedish is considered an advantage, but not necessary.
We offer
1-2 Postdoctoral Research Fellows will be hired for a fixed term position beginning earliest at 1.4.2024 and ending latest on 31.8.2027. The length of the contract and the start date can be negotiated. Position can be filled-in as full time or part time. A trial period of 6 months applies to all our new employees.
The salary for a Postdoctoral Research Fellow will be based on the job demands and the employee’s personal performance as presented in University Salary System . According to the criteria (for teaching and research staff), the position of a postdoctoral researcher is placed at level 5-6, in addition to which employees receive performance-based salary. Depending on the career stage the salary is typically between 3500€ to 4000€ per month.
We offer a wide range of staff benefits, such as occupational health care, flexible working hours, excellent sports facilities on campus and several restaurants and cafés on campus with staff discounts. Please read more about working at Tampere University .
How To Apply
Please submit your application through our online recruitment system (see the link below the add). The closing date for applications is on March 6, 2024 (at 23:59 EET/UTC +2). Interviews will be held between March 11 and March 22.
Please write your application and all accompanying documents in English.
The following documents must be attached (in PDF format) to the online application:
Curriculum vitae (following TENK guidelines )Letter of
List of publications (following Academy of Finland guidelines )
Motivation letter: a short description (max 2 pages) why you are interested in the project (as described above); how the project is supported by your past research, key strengths, and research expertise; and your motivation to work as part of a research team.
Recommendations (you may add a contact info of max 2 references).
For more information, please contact
Tenure track professor Kati Heinonen-Tuomaala, kati.heinonen-tuomaala(at)tuni.fi
Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fi
Tampereen yliopiston yhteiskuntatieteiden tiedekunta (psykologia) hakee 1-2 tutkijatohtoria Suomen Akatemian rahoittamaan ”Varhaislapsuuden suolistomikrobiston yhteydet lapsen mielenterveyteen ja kognition kehitykseen”-hankkeeseen aikavälille 1.4.2024-31.8.2027. Tehtävä voidaan täyttää kokoaikaisena tai osa-aikaisena.
Tehtävänkuvaus
Tutkijatohtorin tehtävänä on tutkia suolistomikrobiston roolia lapsen mielenterveyden ja kognition kehitykselle. Tutkijatohtorin tehtäviin kuuluvat aineiston käsittely ja analysointi sekä tieteellisten artikkelien kirjoittaminen. Tutkijatohtorin osallistuu myös uuden tutkimusaineiston keruun suunnitteluun ja keräämiseen. Valittavalla henkilöllä on mahdollisuus vaikuttaa oman tutkimuksensa painotuksiin hankkeen yleisten tavoitteiden puitteissa.
Tehtävään valittavan edellytetään aktiivisesti edistävän tutkimustaan ja julkaisevan tutkimustuloksiaan korkeatasoisissa tieteellisissä lehdissä sekä osallistuvan apurahahakuihin. Lisäksi hänen tulee osallistua säännöllisiin projektikokouksiin, hankkeen tutkimusryhmän toimintaan sekä esittelevän tutkimustuloksiaan oman alansa seminaareissa sekä tieteellisissä konferensseissa. Tehtävään valitun edellytetään osallistuvan myös opetukseen ja väitöskirjatöiden ohjaukseen.
Hakuohjeet
Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta. Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).
The Faculty of Science, Department of Biology, at the University of Turku invites applications for contract-based, fixed term postdoctoral researcher position for two years. Employment starts on as agreed.
The selected candidate will work within the framework of a Research Council of Finland-funded project ”Fungal parasitism along a salinity gradient: an overlooked driver of marine phytoplankton blooms” (led by Dr Silke Van den Wyngaert, https://uglylab.science/).
The project aims to explore the molecular mechanisms of salinity adaptation in chytrids, zoosporic fungi from the Chytridiomycota phylum. As lethal parasites of phytoplankton, chytrids significantly influence the dynamics of phytoplankton blooms, impacting key ecosystem processes. While traditionally isolated from and studied in freshwater environments, chytrids are increasingly observed in brackish and marine waters. The salinity barrier is considered one of the most difficult physicochemical barrier to cross, playing a crucial role in determining microbial community composition. Molecular mechanisms of salinity adaptation in chytrids will be investigated through comparative genome and transcriptome analyses.
Job description The selected candidate will:
conduct assembly and genome analysis of chytrid cultures and single cells isolated from the Baltic Sea.
perform comparative genome analysis and analyze transcriptome experiments.
draft study outcomes for submission to peer-reviewed journals.
have the opportunity to contribute to other ongoing projects, including targeted fungal parasite omics analyses.
Orion’s Immuno-Oncology (IO) research team is looking to recruit an enthusiastic and motivated Immunology and flow-cytometry scientist to join the IO team. In this role you will contribute to IO target identification and validation, coupled with being responsible for supporting multi colour flow cytometry needs. In this role you have a unique opportunity to contribute in a range of treatment modalities ranging from small molecules, large molecules (bispecific & monospecific antibodies) and CAR T cells.
The responsibilities of this role include the following (including, but not limited to);
Design and perform in vitro immune assays and treatment with oncology drugs in conjunction with internal project teams.
Desing multi-colour flow cytometry antibody panels to detection and FACS sorting of a range of Immune cells.
Establish and validate human and mouse in vitro primary immune cells assays to define the mechanism of action of IO drugs.
Co-ordinate with the line-manager to ensure timely delivery of data and report if any issues encountered or foreseen.
Be responsible person for flow cytometry training for internal staff and regular maintenance of flow cytometry and cell sorter instruments.
Provide clear reports and presentations as required and participate in project team meetings and organisation meetings.
Working in close collaboration with other scientists and technicians.
This is a fixed-term contract of employment (parental leave) and location is Turku, Finland.
Description Of Unit
Immuno-Oncology (IO) is one of the three Research teams in Orion’s Oncology R&D. IO team is accountable for novel drug discovery projects, identification of unmet need, identification & experimental validation of potential IO drug targets within state-of-the-art laboratories and technologies.
We Offer
We offer you the opportunity to show your talent in one of the most innovative* companies in Finland. You get a chance to work in a challenging field of work with excellent colleagues. You will also have the chance to do meaningful work and build the future of Orion. We are striving for excellence in everything we do. We succeed, learn together and appreciate each other. You’ll be empowered to deliver value. Please visit our website to find further information about Orion as an employer.
Requirements
To be a successful ideally you should have the following educational and professional work experiences:
PhD degree in Immunology or related field with 2+ years of relevant experience.
Strong and deep knowledge building multi colour panels, flow cytometry and cell sorter instruments
Strong in vitro research experience using primary immune cells assays is a must
Demonstrate ability to independently design, conduct and interpret the data from complex in vitro immune cell assays and flow cytometry is a must.
Demonstrate proficiency in isolation of immune cells and processing samples for multi-colour flow cytometry, multiplex ELISA, IHC, single cell RNA sequencing and gene expression analysis.
Competency in using graph pad prism, flowjo, nSolver software and other standard office software.
Excellent attention to details with strong communication skills.
Flexibility and willingness to learn new techniques and take additional responsibilities as a member of the research team.
Additional Information
We look forward to hearing from you as soon as possible, so please send your application in English by 10th March at the latest.
For further information, please contact Dr Anil Thotakura, Head of Immuno-oncology, +358 50 966 7229 on 28th Feb 4:00 to 5:00pm or 4th March 4:30 to 5:30pm or 7th March 4:00 to 5:00pm
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person. Orion Corporation operates in more than 30 countries, where we Orionees, 3600 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.
Terveyden ja hyvinvoinnin laitoksen Terveysturvaajat-osaston Infektiotautien ja resistenssin torjunnan ohjaus -tiimi hakee Erityisasiantuntijaa määräaikaiseen työsuhteeseen ajalle 2.4.2024-31.12.2024.
THL:n Terveysturvaajat-osaston Infektiotautien ja resistenssin torjunnan ohjaus -tiimi vastaa hoitoon liittyvien infektioiden ja moniresistenttien bakteereiden seurannasta ja torjunnasta, HIV ja hepatiitti C virusinfektioiden seurannasta, Euroopan tautiviraston (ECDC) kenttäepidemiologian koulutusohjelman (EPIET) koulutettavien ohjauksesta sekä osallistuu kansallisiin ja kansainvälisiin infektioepidemiologian hankkeisiin.
Erityisasiantuntijan tehtävä on erittäin vaativa tartuntatautien seurannan ja torjunnan asiantuntijatehtävä, jossa päätoiminta-alueet ovat ECDC:n kenttäepidemiologian koulutusohjelman (EPIET) johtaminen Suomen osalta. Tehtävään kuuluu vastuu uusien koulutettavien haastatteluista ja valintaprosessista, koulutusohjelman suunnittelusta, toteutuksesta ja arvioinnista sekä ohjelman jatkuvasta kehittämisestä yhdessä ECDC:n kanssa. Koulutusohjelma suunnitellaan ja toteutetaan yhdessä ECDC:n sekä THL:n ja kentän asiantuntijoiden kanssa. Koulutusohjelmaan sisältyy myös erilaisten kurssien ja koulutustapahtumien järjestämistä eri maissa oleville EPIET-koulutettaville.
Lisäksi tehtävään sisältyy infektioepidemiologian asiantuntijana toimiminen infektiotautien kansallisessa ja kansainvälisessä seurannassa ja torjunnassa sekä infektioepidemiologian tutkimushankkeissa.
Odotamme tehtävässä valmiutta toimia koordinoivana asiantuntijana kansainvälisissä hankkeissa infektioepidemiologian alalla.
Kyseessä on osaston toimintojen kannalta keskeinen asiantuntijatehtävä, jolla on merkittävää kansallista ja kansainvälistä vaikutusta.
– akateemista loppututkintoa lääketieteen, kansanterveystieteen tai luonnontieteiden alalta – tohtorin tutkintoa tai 2-vuotisen kenttäepidemiologiakoulutuksen suorittamista (EPIET, EIS tai vastaava), tai muuta näihin verrattavissa olevaa kokemusta epidemiologian alalta – tuntemusta kansallisista ja kansainvälisistä tartuntatautien seurantajärjestelmistä, epidemiaselvityksistä ja infektiosairauksiin kohdistuvasta tutkimustyöstä sekä monipuolista kokemusta alan tehtävistä
Tehtävässä tarvittava muu kielitaito
Englanti
Suullinen osaaminen: Erinomainen
Kirjallinen osaaminen: Erinomainen
Tarjoamme sinulle – kansainvälistä yhteistyötä Euroopan tartuntatautien ehkäisy- ja valvontaviraston (ECDC) sekä kansainvälisiin hankkeisiin osallistumisen kautta – itsenäisen työn mukavien ja osaavien asiantuntijoiden ympäröimänä – joustavat työajat ja hyvät mahdollisuudet etätyöhön
Selvitykset
Virkaan tai tehtävään valittavasta henkilöstä voidaan tehdä hakijan suostumuksella perusmuotoinen henkilöturvallisuusselvitys (turvallisuusselvityslaki 726/2014). Menettelystä ja selvityksen kohteen oikeuksista löytyy tarkempia tietoja osoitteessa www.supo.fi.
Toivomme hakemukset ensisijaisesti sähköisinä Valtiolle.fi-palvelun kautta. Voit kuitenkin hakea tätä työpaikkaa myös toimittamalla hakemuksesi kirjaamon postiosoitteeseen. Sekä hakemuksessa että kirjekuoressa tulee mainita haettavan tehtävän ID-numero. Kirjeen tulee olla perillä hakuajan päättymiseen mennessä.
Terveyden ja hyvinvoinnin laitoksen kirjaamo
PL 30 00271 Helsinki
kirjaamo(at)thl.fi
Työnantaja
Terveyden ja hyvinvoinnin laitos (THL) on asiantuntija- ja tutkimuslaitos. Tuotamme tietoa, työkaluja ja ratkaisuja terveys- ja hyvinvointialan päätöksenteon ja toiminnan tueksi. Vahvuuksiamme ovat merkityksellinen työ, osaava ja intohimoisesti työhönsä suhtautuva henkilöstö ja loistavat tietovarannot. Teemme kansainvälisesti ja kansallisesti arvokasta tutkimusta ja sovellamme sitä suomalaisen yhteiskunnan tulevaisuuden rakentamiseen.
Sijainti Helsinki
Voit tehdä työtä jossain seuraavista toimipisteistämme Helsinki Mannerheimintie 166 00300 Helsinki
Tutustu työnantajaan Perustiedot
Muut tehtävään liittyvät tiedot Muut työpaikkaan liittyvät tiedot: THL:ssä on joustavat työajat, jotka mahdollistavat työn ja vapaa-ajan yhteensovittamisen. Henkilöstöetuihimme sisältyvät myös kattavat työterveyspalvelut sekä liikunta-, kulttuuri-. hyvinvointi- ja toimipaikkojen lounasetu.
Lue lisää THL:stä työnantajana: https://thl.fi/fi/thl/tyonhakijalleTehtävän taso: AsiantuntijatasoEtätyö: Mahdollisuus työskennellä etänäMääräaikaisuuden peruste: Työn luonneMääräaikaisuuden perusteen lisätietoja: ProjektityöTyöaikamuoto: VirastotyöaikaKoeaika: 3 kkPalkkauksen peruste: Tehtävä sijoittuu Terveyden ja hyvinvoinnin laitoksen palkkausjärjestelmän vaativuustasoon 4, jossa tehtäväkohtainen palkka on 4405,68 €/kk. Tehtävässä maksetaan lisäksi henkilökohtaiseen työsuoritukseen perustuvaa palkanosaa, (uudella henkilöllä yleensä enintään 18 % riippuen henkilön osaamisesta ja työkokemuksesta).
