Ajankohtaista

Tällä sivulla ilmoitetaan yhdistyksen tapahtumista sekä muista ajankohtaisista asioista.

Two fixed term postdoc positions (2 years, extendable) are available at Centre for Molecular Medicine Norway (NCMM)

24.2.2020 | Avoimet työpaikat

Two fixed term postdoc positions (2 years, extendable) are available at Centre for Molecular Medicine Norway (NCMM). We welcome applications both from recent PhD graduates and more experienced scientists. Experimentalists, computer scientists and hybrids alike are encouraged to apply. Researchers aiming for academic principal investigator positions in the future are encouraged to apply for independent funding during their first year in NCMM.


The aim of the Haapaniemi group is to build a gene editing platform that can be used to correct patient-specific mutations in ex vivo cell therapies for genetic immune and other rare childhood diseases. We will use high-throughput biology techniques to optimize, develop and understand the CRISPR-Cas system that forms the base of the platform, and develop and implement methods to evaluate its safety in a clinical setting. We will use the modified gene editing technologies for the benefit of the patients in the Nordic hospitals

.
The aim of the Saarela group is to identify novel genetic causes for rare and complex immune and hematological diseases and improve their diagnostics and treatment. We use modern genetic and informatics methods, including deep learning, to analyze genomics and clinical data, as well as molecular genetics and cell biology approaches to understand molecular bases of the diseases and normal immune function. We will also use NGS based methods to identify molecular diagnosis for patients suffering from rare genetic disorders to enable accurate prediction of disease course, targeted treatment and genetic counselling.

Link to the whole job description:

https://www.jobbnorge.no/en/available-jobs/job/182195/two-postdoctoral-fellows-crispr-gene-therapy-and-immunogenetics-groups-haapaniemi-saarela

Open positions for a Postdoctoral Researcher & Project Researcher at the Faculty of Health Sciences, A.I. Virtanen Institute for Molecular Sciences, Kuopio Campus

24.2.2020 | Avoimet työpaikat

The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 2 500 degree students and about 450 PhD students in the Faculty. The faculty has 680 staff members. http://www.uef.fi/en/ttdk/etusivu
We are now inviting applications for
a Postdoctoral Researcher or Project Researcher (Neurosciences) &
a Project Researcher (Neurosciences) position (Faculty of Health Sciences, A.I. Virtanen Institute for Molecular Sciences, Kuopio Campus)

More information at https://www.uef.fi/en/uef/en-open-positions

Doctoral candidate position available in Folkhälsan Research Center and University of Helsinki located in Meilahti campus

24.2.2020 | Avoimet työpaikat

This opportunity has arisen through Dr. Shintaro Katayama as a junior PI supported by Jane and Aatos Erkko Foundation. The joint research groups with Professor Juha Kere are base in the Folkhälsan Research Center at Helsinki, Research Programs Unit at University of Helsinki, and Department of Biosciences and Nutrition at Karolinska Institutet. The focus of the work is aimed at understanding where and when RNAs are regulated in various human developmental stages [*1] or the cell types [*2] to understand the disease [*3] or to use the deregulated RNAs for diagnosis [*4]. For the aim, the groups are willing also to develop new molecular and/or bioinformatics methods [*5, 6, 7].

As part of the joint research groups, there is a position available for a PhD candidate studying RNA (not DNA) editing in human normal epidermal cells and the model cells using high-throughput sequencing at Folkhälsan Research Center and University of Helsinki. The main duties will involve the establishment of a genome-scale analysis pipeline or tools to map the RNA editing sites in human cells using a nanopore sequencer as well as computational analysis of the experimental results. The analysis includes the integration of the other experimental results using other equipment or methods to investigate the association between gene expression and RNA editing.

The successful candidates should have (or be close to completed) an MSc in Bioinformatics, Biostatistics, Systems Biology, Computational Biology or a related field. Experiences of an open-source software package development will be plus. Applicants interested in any of the above research areas will be considered.

Please send your application to shintaro.katayama(at)folkhalsan.fi latest Sunday March 15 2020. Please include a brief letter motivating your interest and goals, a CV (2 pages, specifying your education and expertise in the topics listed above), and a list of possible previous publications. The selection processes will be conducted in April and the post is available from summer 2020. The funds for this position are available for 24 months in the first instance.

Selected publications:

*1 Töhönen, V. & Katayama, S. et al. Nat Commun 6, 8207 (2015).

*2 Hirabayashi, S. & Bhagat, S. et al. Nat Genet 51, 1369–1379 (2019).

*3 Katayama, S. & Panelius, J. et al. J. Invest. Dermatol. 139, 2058–2061.e4 (2019).

*4 Katayama, S. & Hammar, KS. et al. Eur. Respir. J. 55, 1901330 (2020).

*5 Katayama, S. et al. J. Bioinformatics 29, 2943–2945 (2013).

*6 Krjutškov, K. & Katayama, S. et al. Hum. Reprod. 31, 844–853 (2016).

*7 Katayama, S. et al. BMC Bioinformatics 20, 418–9 (2019).

Research Associate/PostDoc/Sr. Res. Associate positions are available immediately in the Department of Anesthesiology at the University of Miami Miller Medical School

24.2.2020 | Avoimet työpaikat

Research Associate/PostDoc/Sr. Res. Associate positions are available immediately in the Department of Anesthesiology at the University of Miami Miller Medical School.  The research focuses on the mechanisms of neuropathic pain and opioid abuse with gene therapy supported by the NIH funded projects. The positions open to recent PhD and/or MD with background in molecular biology, histology/imaging, or a related discipline. 

Priority to applicants with skills of Animal Surgery of nervous system/pain-related Behavioral Testing/Neuropharmacology, or Genomic/Epigenetic, Exosome, luciferase assay, ChIP-seq, RNA-seq, gene cloning, DNA damage and repair etc. is given. 

Applicants with Master degree and strong background related to this research skill are also available. The title may be changed based on experience. Please send your CV to: Dr. Hao, Department of Anesthesiology, University of Miami Miller Medical School, Miami, FL 33136. shao@med.miami.edu

Suomen Solubiologit ry:n vuosikokous 13.2.2020

16.2.2020 | Ajankohtaista

Suomen Solubiologit ry piti vuosikokouksensa torstaina 13.2.2020 Biomedicumissa, Helsingissä ennen Suomen Sidekudostutkijat ry:n kanssa järjestettyä yhteisseminaaria.

Yhdistys sai kokouksessaan uuden hallituksen vuodelle 2020:

  • Elina Siljamäki (Puheenjohtaja)
  • Jan Koski (Varapuheenjohtaja)
  • Johanna Matilainen (Tiedotussihteeri)
  • Kai Härkönen (Rahastonhoitaja)
  • Linda Kauppinen (Hallituksen jäsen)
  • Terhi Heino (Hallituksen jäsen)
  • Jenni Tuominen (Hallituksen jäsen)
  • Emilia Kettunen (Hallituksen jäsen)
  • Niko Kangasniemi (Hallituksen jäsen)

Haluamme vielä kerran kiittää Anne-Mari Koivistoa ja Eveliina Korhosta kuluneista hallitusvuosista sekä toivottaa tervetulleiksi uudet hallituksemme jäsenet, Kai Härkösen ja Terhi Heinon!

The Joint Meeting of the Finnish Connective Tissue and Cell Biology Societies

15.2.2020 | Ajankohtaista

We had a great seminar of the Finnish Society for Cell Biology and Connective Tissue Society (from now on The Finnish Society for Matrix Biology) in Biomedicum, Helsinki on Thursday 13th. The Finnish Society for Cell Biology wants to thank all the speakers, participants and organizers for an amazing day!

The Joint Meeting of the Finnish Connective Tissue and Cell Biology Societies
Jarkko Koivunen and Elina Siljamäki opening the joint meeting of Finnish Connective Tissue Society and The Finnish Society for Cell Biology
Sylvie Ricard-Blum starting the first session
Johanna Ivaska (University of Turku): Adhesion regulated mechanotransduction in cancer
Eija Jokitalo from the University of Helsinki giving a lecture about endoplasmic reticulum structure, dynamics and function
Sponsor talk by Lauri Paasonen (UPM biofore)
Coffee break before the second session!
Janine Erler from the University of Copenhagen starts the second session by asking ”How cancer builds its home”
Sara Wickström from the University of Helsinki discussing mechanical forces and the nucleus
Aleksi Isomursu from the Ivaska Lab, University of Turku
Sanna Pasonen-Seppänen from the Institute of Biomedicine, University of Eastern Finland giving a talk about hyaluronan in tumor-stroma interaction
Diana Toivola from Åbo Akademi and University of Turku: Colonic epithelial cell intermediate filaments protect from colitis and colorectal cancer
Artemis Filippou from the University of Helsinki describing how the inhibition of anoctomin 1 induces apoptosis via downregulation of mcl-1 in head and neck squamous cell carcinoma
Valerio Izzi’s (University of Oulu) presentation about cancer matrisome and microenvironment finishes our awesome seminar
Scientific discussions continuing at dinner. Thank you all for participating our seminar!

Post doc position in molecular asthma immunology in Gotheburg, Sweden

10.2.2020 | Avoimet työpaikat

Krefting Research Centre, Institute of Medicine, University of Gothenburg, is recruiting a post-doctoral researcher for a 2-year contract. Krefting Research Centre (http://krefting.gu.se) is a centre funded by the VBG Group Herman Krefting Foundation for Asthma and Allergy Research. The main research at the Krefting Research Center focuses on asthma and allergies, and includes basic inflammation research, clinical studies and population-based studies. The basis for the research is the ongoing ”West Sweden Asthma Study”, one of Europe’s largest population-based studies of asthma that was started in 2008 in Västra Götaland.

To qualify as a postdoctoral researcher the applicant should hold a PhD in a relevant subject. Since postdoctoral constitutes a qualifying appointment for junior researchers, we aim to target those who have a doctoral degree not older than 3 years from the application deadline.

More information and application at https://www.gu.se/english/about_the_university/job-opportunities/vacancies-details/?id=5563

Deadline for applications is March 2, 2020.

Genetiikan tuotespesialisti – Triolab

5.2.2020 | Avoimet työpaikat

Haemme genetiikan tuotespesialistia Turun, Helsingin tai Tampereen toimipisteeseemme.

Pääasiallisena työtehtävänäsi on laajentuvan genetiikan ja onkologian valikoimamme tuotteiden myynti, markkinointi ja tuotetuki koko Suomen alueella, sekä Baltian myyntiorganisaation tukeminen. Asiakaskuntaasi ovat mm. yliopisto- ja keskussairaaloiden laboratoriot ja osastot, yksityisen terveydenhuollon palveluntarjoajat sekä yliopistot ja tutkimuslaitokset. Lisäksi sinulla on työssäsi merkittävä rooli tuotevalikoimamme sekä asiakassuhteidemme kehittämisessä ja vahvistamisessa yhteistyössä muun organisaatiomme kanssa.

Odotamme sinulta työtehtäviin soveltuvaa koulutusta (humaani- tai syöpägenetiikan alan korkeakoulututkinto tai vastaava) ja/tai kokemusta vastaavista työtehtävistä sekä erityisesti intoa ja halukkuutta asiakaslähtöiseen kenttätyöhön. Kokemus kliinisen genetiikan laboratoriossa työskentelystä ja NGS-teknologian käytöstä katsotaan eduksi. Sinulla on hyvä suomen ja englannin kielen suullinen ja kirjallinen taito, ruotsin kielen taito on plussaa. Ajokortinkin tarvitset. Olet valmis matkustamaan kotimaassa ja Baltiassa viikoittain.

Tarjoamme myyntihenkisellä asenteella varustetulle avoimelle ja sosiaaliselle osaajalle mielenkiintoisen ja haastavan työn reilussa ja mutkattomassa, töitä tosissaan tekevässä organisaatiossa sekä kilpailukykyisen palkkauksen ja työsuhde-edut. Tehtävä on määräaikainen äitiysloman sijaisuus, ja paikka täytetään heti sopivan henkilön löydyttyä.

Lähetä hakemuksesi, ansioluettelosi ja palkkatoiveesi sähköpostitse 23.2.2020 mennessä osoitteeseen rekry@triolab.fi. Älä suotta aikaile, sillä alamme käydä hakemuksia läpi sitä mukaa, kun niitä tulee.

Lisätietoja antaa Triolab Oy:n myynti- ja markkinointijohtaja Jussi Kurittu (p. 0400 800 917) – tavoitettavissa varmimmin ti 11.2. ja pe 14.2. klo 13-15.

Triolab Oy on vuonna 1986 perustettu korkealaatuisten diagnostiikka- ja tutkimustuotteiden myyntiin, tuotetukeen ja huoltoon erikoistunut asiantuntijayritys. Meillä työskentelee yli 40 alan ammattilaista. Triolabin pääkonttori ja varasto sijaitsevat Turussa. Sen lisäksi meillä on aluetoimistot Helsingissä ja Tampereella. Yrityksemme kuuluu 600 ammattilaisen pörssinoteerattuun AddLife-konserniin, jonka päämarkkina-alue on Pohjoismaat.

Technical assistant – Extracellular Vesicle group (Pia Siljander), Molecular and Integrative Biosciences research program, University of Helsinki

4.2.2020 | Avoimet työpaikat

An enthusiastic and goal-oriented technical assistant is sought to the Extracellular Vesicle group of Pia Siljander in the Molecular and Integrative Biosciences research program, University of Helsinki, located in Viikki. Part of the project may also be carried out in the Institute of Molecular Medicine Finland, Helsinki. Our laboratory, which also hosts a dedicated EV Core facility, specializes in cutting-edge EV technologies and research.

Projects and responsibilities

We have two ongoing interlinked projects funded by Business Finland where we need technical assistance for the development of EV isolation and analytical technologies and standardization. The laboratory work in project one involves testing of a new technology to carry out high-throughput isolations of EVs from plasma by testing different conditions, plate formats and automatization in comparison to existing methods. The quality of the isolates will be evaluated by EV methodologies (including flow cytometry), through omics testing and usual molecular biology methods. The work also involves analysis of EV samples originating in the second project by the technologies available in the EV group and core and through the other project participants. This project also develops standardization for flow cytometry and materials for standardization.

Qualifications

A successful candidate has good skills in the essential molecular biology, cell culture and biochemistry techniques, e.g. Western blotting and working with multi-well assays. We value prior experience in flow cytometry, data management and data analysis. The successful candidate has an active approach to addressing lab needs, keeps meticulous records of the experimentation and is a dedicated team player with excellent self-management skills.

Salary, applications and contact information

Position will be available 10.2.-31.12.2020. The start date can be set according to agreement, but preference will be given to candidates who can start as early as possible. Salary will be based on the University salary scheme depending on the degree/work experience.

Position will be filled as soon as a suitable candidate is found.

Applications should have a cover letter describing the qualifications of the candidate, CV and two references from past employment and be sent to maija.puhka@helsinki.fi and pia.siljander@helsinki.fi.

PhD student position available in the Kidney development lab located in Meilahti campus at HiLIFE, University of Helsinki

4.2.2020 | Avoimet työpaikat

The projects focus on studying stem / progenitor cell biology developing kidney and aim to understand causes of congenital renal malformations in humans.

Our group studies renal development with the help of different genetically modified mouse models and different in vitro culture systems. We are specifically interested in understanding how kidney growth through ureteric bud branching morphogenesis is regulated and which kind of cellular events drive its complex pattern. Our projects also explore how growth factor induced signaling controls nephron progenitors during their self-renewal and differentiation into the functional units of the kidneys, the nephrons.

All applicants with genuine interest in developmental and stem cell biology are encouraged to submit a motivation letter, CV and possibly reference letter (if applicable) to satu.kuure(at)helsinki.fi before the deadline on February 28, 2020.


For further information, see Kuure lab or contact the group leader Satu Kuure (satu.kuure(at)helsinki.fi , +358 2941 59395).


Selected publications:

Takko, H., Pajanoja, C., Kurtzeborn, K, Hsin, J., Kuure, S. and Kerosuo, L. ShapeMetrics: a userfriendly pipeline for 3D cell segmentation and spatial tissue analysis Dev. Biol., Conditionally accepted.

Kuure, S. Sariola, H. Mouse models of congenital kidney anomalies. Chapter 5 in book Animal models of human birth defects, Springer Nature Singapore Pte Ltd. In press.

Dapkunas A, Rantanen V, Gui Y, Lalowski M, Sainio K, Kuure S, Sariola H. Simple 3D culture of dissociated kidney mesenchyme mimics nephron progenitor niche and facilitates nephrogenesis Wnt-independently. Sci Rep. 2019 9(1):13433.

Kurtzeborn, K., Kwon, H.N., Kuure, S. 2019. MAPK/ERK signaling in regulation of renal differentiation. Int J Mol Sci. 2019 20(7).

Li, H., Jakobson, M., Ola, R., Gui, Y., Kumar, A., Sipilä, P., Sariola, H., Kuure, S*. Andressoo, J-O*. 2019. Development of the urogenital system is regulated via the 3’UTR of GDNF. Sci Rep, 9(1):5302.

Zhang, H., Bagherie-Lachidan, M., Badouel, C., Enderle, L., Peidis, P., Bremner, R., Kuure, S., Jain, S., McNeill, H. 2019. FAT4 fine-tunes kidney development by regulating RET signaling. Dev Cell, 48(6):780-792.e4.

Ihermann-Hella, A., Hirashima, T., Kupari, J., Kurtzeborn, K., Li, H., Kwon, H.N., Cebrian, C., Soofi, A., Dapkunas, A., Miinalainen, I., Dressler, G.R., Matsuda, M., Kuure, S. 2018. Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation. Stem Cell Reports, 11(4):912-928.