15.10.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3732160736
About the job
Are you interested in plant biotechnology and plant-derived high-value compounds and looking for a new postdoctoral opportunity in the field? Would you like to do impactful research in the cutting edge of natural sciences with superb colleagues who are top expert in their field? VTT might be just the place for you. If you are an international talent searching for a new opportunity, read more about the benefits of living in Finland and VTT’s support for relocation here !
VTT is one of the leading applied research organisations in Europe. What unites us are curiosity, a passion for learning and a purpose: to solve the biggest challenges of our time and turn them into sustainable growth and well-being. Our cross-disciplinary community of over 2000 brilliant minds is focused on creating impact through science-based innovation. Get to know us further by exploring VTT’s tech & infra.
We are now looking for a Post-doctoral Scientist to join our Plant Biotechnology team. As a research scientist, your key goal is to engineer metabolic pathways towards capsinoids and capsaicinoids both in plants and yeast using novel engineering tools. In this position, you will be the responsible researcher in an Academy of Finland -funded project. You get to develop a biotechnological production system for the selected high-value plant metabolites using state-of-the-art techniques.Our team, Plant Biotechnology, works on developing plants, plant cells, microalgae, and other plant-based raw materials for the sustainable production of biomass, ingredients, high-value chemicals, and proteins. Product development can be facilitated by metabolic engineering including synthetic biology. Our approaches enables a stable supply in combination with safe and contained production processes. This results in economical and clean products. We offer plant cell and tissue culture technology from initiation up to industrial scale.This position supports long term career opportunities in applied research, industry or academia. The focus is in advancing specified research targets and active publication of research results. VTT started a Postdoc programme in 2023 to develop new ways to support scientific excellence and to strengthen career paths from universities to VTT. VTT wants to provide development opportunities for recent university PhDs in applied research and industry collaboration. As a Postdoctoral Researcher at VTT, you are able to make an impact for our customers and society. Our researchers work closely together with industry, often in interdisciplinary research groups. VTT has excellent and internal services to support your research work.The position is located in Espoo and it is a 2 year temporary contract.
Your responsibilities as a Post Doctoral Researcher:
- Study biosynthetic pathway engineering in plants and yeast in a defined project
- Conduct laboratory work including cell culturing, molecular biology work and chemical analyses
- Plan experiments, analyse the data and communicate project results
- Report the results regularly to the project team and prepare scientific publications
Who we are looking for:
- You have a doctoral degree related to plant science
- Track record in metabolic engineering of plants
- Experience in genome editing techniques
- Experience with yeast transformation is a plus
As a person, we hope that you are:
- An open-minded and innovative person with a vision on longer term research needs. You have a strong passion for work. You are eager to work with new topics and methods, even out of your comfort zone to achieve the set ambitious goals. We appreciate the ability to tolerate pressure and maintain good work-life balance, as well as the willingness to collaborate with experts and partners across different fields.
With VTT, you’ll enjoy:
- Natural sciences with an impact. VTT works on the cutting-edge of natural sciences, and we’ve invested into building state-of-the-art research facilities for natural sciences, such as the Bioruukki pilot infrastructure for bio- and circular economy. Our research agenda is dedicated to solving systemic and technological challenges, such as reaching carbon neutrality and unleashing the power of synthetic biology. That means that at VTT, your expertise in natural sciences will go towards creating real impact. Read more about our strategy – the path of exponential hope .
- Superb colleagues and community. With VTT, you’ll join a community of over 2000 multidisciplinary experts who foster a culture of trust, openness and sharing knowledge. We work truly across disciplines, and house all the cutting-edge sciences from quantum computing to synthetic biology under one roof. Collaborating with superb colleagues is a source of learning, inspiration, and fun. Read more about our organisational culture as the builder of the world’s most meaningful place to work.
- Nordic work–life balance. Working in Finland, the world’s happiest country enables an excellent quality of life. At VTT, we make our people’s well-being a strategic priority. We offer six weeks of paid vacation a year. Our benefits include comprehensive occupational healthcare and a range of well-being services, such as exercise, culture benefits, and hobby clubs. If you are an international talent searching for a new opportunity, read more about the benefits of living in Finland and VTT’s support for relocation here .
- A great career in research. We offer long-term positions and flexible career paths in top-level research. People tend to stay with us for over ten years, as you can advance to different roles and responsibilities within VTT. At VTT, researchers have the flexibility and independence to affect the content of their work. Combining cutting-edge academic research and applied customer projects keeps your career path interesting.
Apply now and join our community of brilliant minds! Please send your CV and answers to 3 position specific questions with your salary request via our recruitment system as soon as possible but at the latest by 22nd of October 2023. We will process applications as they come in, and fill in the position as soon as we find the right candidate. A security clearance procedure may be conducted during the recruitment process.
Interested and want to hear more?
For further information, please contact Research Team Leader Heiko Rischer heiko.rischer@vtt.fi
VTT
VTT is a visionary research, development and innovation partner. We drive sustainable growth and tackle the biggest global challenges of our time and turn them into growth opportunities. We go beyond the obvious to help the society and companies to grow through technological innovations. We have 80 years of experience of top-level research and science-based results. VTT is at the sweet spot where innovation and business come together.
VTT – beyond the obvious.
Location: Tekniikantie 21, Espoo
15.10.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3731642951
About the job
Tampere University and Tampere University of Applied Sciences create a unique environment for multidisciplinary, inspirational and high-impact research and education. Our university community has its competitive edges in technology, health and society. www.tuni.fi/en .The BioMediTech Unit of the Faculty of Medicine and Health Technology jointly with StemSight Oy is looking for a Postdoctoral Research Fellow specializing in cell and molecular biology.
The position will be filled for a fixed-term period of two years and is funded by the Finnish Research Impact Foundation. Half of the work will be carried out at StemSight Oy although employment contract will be made with Tampere University.The Faculty of Medicine and Health Technology (MET) is committed to high quality research and education in the fields of biomedical engineering, biotechnology, medicine, and health technology. We conduct basic, applied, clinical, and translational research in collaboration with Tampere University Hospital (TAYS). Our existing research areas in health research include biomedical engineering fields from biomaterials and microtechnologies to health data science, cell and molecular biology, with applications in areas such as cancer, cardiovascular and celiac diseases, immunology, and ophthalmology.
Professor Heli Skottman’s eye regeneration group develops novel human stem cell-based tools for corneal and retinal repair through cell transplantation and ophthalmic in vitro tissue models that can be used to model human-specific eye disorders. For additional details see our web page: https://research.tuni.fi/eye-group/StemSight Oy is a spinout company from Tampere University, commercializing iPSC-based therapies for the treatment of corneal blindness. More information at https://www.stemsight.fi/
Job Description
We are seeking a talented and motivated postdoctoral researcher to independently work with human induced pluripotent stem cells and their differentiation towards corneal endothelial cells. The candidate will be responsible for improving and optimizing a previously developed differentiation process to ensure research translation towards clinical and commercial use. The primary emphasis will be on developmental biology, advanced cultivation of human pluripotent stem cells, and their guided differentiation through the manipulation of signaling pathways. The research necessitates a profound understanding and passion for molecular signaling regulation within cells and employing a diverse array of molecular techniques, which encompasses advanced flow cytometry and imaging methodologies. In addition, there will be a need for data analysis, the creation of publications and reports. Importantly, the job includes active working and communication in the interface of academic research and industrial R&D and collaboration with academic and industrial R&D colleagues and support staff, both internally and within external networks.
Requirements
- An applicable doctoral degree in the field of medicine, cell biology or molecular biology.
- Versatile and independent researcher expertise in cell biology.
- A solid background in cell and molecular biology as well as culturing of human cells.
- Candidates with additional research experience with human pluripotent stem cells will be highly valued.
- Technical skills in flow cytometry, qPCR and immunofluorescence.
- While experience within the international eye research community is valued, it is not a mandatory requirement.
- Excellent communication skills and fluency in English (both written and oral) will be considered important for the position.
- The position also requires that the candidate is able to meet the responsibilities identified in laboratory and ethical guidelines.
Please describe your relevant experience and skills in detail in the cover letter, and please be prepared to provide proof of your merits when requested.
Tampere University is a unique, multidisciplinary, and boldly forward-looking community. Our values are openness, diversity, responsibility, courage, critical thinking, and learner-centeredness. We hope that you can embrace these values and promote them in your work.
Weoffer
The position is a fixed-term contract for two years, starting on 1 January, 2024. A six-month trial period applies to all new employees.
Salaries are based on job demands and employees’ personal performance in accordance with the salary system of Finnish universities . The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff). A typical salary of Postdoctoral Researcher in this demand level is around 3500-4000 EUR/month.
As a member of the dynamic and innovative international community of Tampere University, you will have access to a range of competitive benefits, including occupational health care services, flexible work schedules, versatile research infrastructure, modern teaching facilities, and a safe and inviting campus area. You will also have a personal fund to spend on sports and cultural activities during your free time. Please read more about working at Tampere University . You can also find more information about us and working and living Tampere by watching our video: Tampere Higher Education Community – our academic playground .Tampere is the largest inland city in Finland and is considered a major academic hub in the Nordic countries. The region is home to a vibrant, knowledge-intensive entrepreneurial community, and the city is an industrial powerhouse with a rich cultural scene and a reputation as a centre of Finland’s information society. Additionally, Finland is known for being one of the most stable, free, and safe countries in the world, based on various ratings by prominent agencies. Tampere is surrounded by stunning nature, with forests and lakes offering countless opportunities for easy-to-access outdoor adventures and refreshment throughout the year.
Read More About Finland And Tampere
- Visit Finland
- This is Finland
- Ministry of Economic Affairs and Employment: Welcome to Finland
- Visit Tampere
HowtoapplyPlease submit your application through our online recruitment system (link provided below). The closing date for applications is October 31st, 2023 (at 23.59 EEST, UTC+2). All application materials, including the accompanying documentation, should be written in English and attached in PDF format.
Please Ensure That Your Application Includes The Following Documents
- Curriculum Vitae
- List of publications
- References from two individuals
- Cover letter, which should include a brief introduction of the applicant, previous research experience, and motivation to apply this position with future perspectives.
Please note that incomplete applications will not be considered. If you have any questions regarding the application process or the position, please do not hesitate to contact us using the contact details provided in the job advertisement.We look forward to receiving your application and thank you for your interest in joining our dynamic and innovative community at Tampere University.
For Further Information, Please Contact
Professor Heli Skottman, tel. +358 50 396 9645, heli.skottman@tuni.fiFor questions regarding the application process, please contact HR Specialist Lilli Sarasvirta, lilli.sarasvirta@tuni.fiTampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fiTampereen yliopiston lääketieteen ja terveysteknologian tiedekunnan BioMediTech-yksikössä on haettavana tutkijatohtorin määräaikainen tehtävä solu- ja molekyylibiologian alalta.Lääketieteen ja terveysteknologian tiedekuntamme on monialainen biolääketieteen tekniikan, bioteknologian, lääketieteen ja terveysteknologian tutkimuksen ja opetuksen korkeatasoinen yksikkö. Teemme kansainvälisesti merkittävää perus- ja soveltavaa tutkimusta.Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta. Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).
Hakuaika tehtävään päättyy 31.10.2023 klo 23.59.
15.10.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3724799374
About the job
Research Program Unit at the Faculty of Medicine at the University of Helsinki invites applications for a fixed-term position of
Postdoctoral Researcher
from 1 November 2023 until 31 October 2024 with a possibility of extension.
The position is available in an Academy of Finland -funded project that investigates the interplay of metabolic reprogramming, epigenetic regulatory landscape, and cancer cell proliferation.
The group is working in the field of cancer biology and epigenetics using state-of-the-art methods such as CRISPR-Cas9 genome editing and transcriptional and epigenomic profiling at single-cell resolution (see e.g., Pihlajamaa et al, Nat Biotech 2023). We utilize diverse cellular models and next-generation sequencing techniques to understand the molecular mechanisms controlling oncogenic gene expression programs and cancer growth. The group belongs to the Applied Tumor Genomics Program in the Research Programs Unit of the Faculty of Medicine at the University of Helsinki providing a vibrant research environment and high-quality infrastructure for modern biomedical research.
Qualifications
- A PhD degree in life sciences with excellent academic record. The default assumption is that the degree requirement must be met by the beginning of the employment.
- Working knowledge of biochemistry, molecular biology, and mammalian cell culture
- Ability to work productively both independently and as part of the team
- Excellent communication skills in English
- The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.
In addition, previous experience in CRISPR/Cas9-mediated genome editing and next-generation sequencing-based functional genomics methods and/or computational analysis of genomic datasets is considered a plus, and candidates with proven track record with at least one first-author publication will be given preference.
What We Offer
- Salary of 3300-3600 euros per month depending on the appointee’s qualifications and experience.
- An exciting project utilizing cutting-edge functional genomics and CRISPR-methods to understand molecular basis of human cancer.
- A position in an ambitious research group with supportive and positive working culture in an international and multi-disciplinary research environment.
- Attractive welfare benefits such as occupational health care provided by University of Helsinki (further information at www.helsinki.fi/en/about-us/careers).
How To Apply
Applications should be submitted through the University of Helsinki Recruitment System via the ”Apply now” button. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi. The closing date for applications is 26 October 2023. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .
For further information on the position, please contact Dr. Päivi Pihlajamaa paivi.pihlajamaa(at) helsinki.fi).
For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk(at) helsinki.fi).
About Us
The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.
The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.
Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.
Posted on Sep 20, 2023.
15.10.2023 | Avoimet työpaikat
https://duunitori.fi/tyopaikat/tyo/orion-in-vitro-research-assistant-sdsuu-17420572
Työpaikkakuvaus
We are looking for a Research Assistant to join our Immuno-Oncology team. You will be based in Turku, Finland and report to Head of Immuno-Oncology. This is a 2 year fixed-term position.
Your main responsibilities will include:
- Culture of both primary and established mammalian cell lines
- Support Oncology scientist with in vitro and ex vivo cell based assays
- Process human blood samples by adhering to Standard Operating Procedures
- Analysis of samples employing specific techniques such as flow cytometry, cell sorting, PCR, western blotting and incucyte assays
- Assist in establishing and improving all procedures and required SOP documentation
- Maintain high standards of housekeeping and participate in routine laboratory decontamination
- Maintenance of laboratory equipment
- Ordering laboratory consumables and maintain stock levels
Description of the unit
Oncology Research is accountable for the discovery of novel targets and drug projects related biology research in the therapy area of Oncology at Orion. Our teams build the R&D Oncology portfolio and Oncology strategy in close collaboration with business and all R&D global functions.
We offer
We are offering an excellent opportunity to work in a dynamic team in a modern laboratory facilities equipped with state-of-art laboratory instrument building up Oncology Research at Orion.
In Orion we have a highly interesting R&D pipeline and enthusiastic working environment with opportunities to use your own strengths to build your competence development. Appreciation of colleagues and continuous development are part of our core values. The culture of Orion R&D is informal and we enjoy working together.
Join us – together we build well-being and do work that we are proud of!
Requirements
In our team, it is important that you are not afraid to take responsibilities and you enjoy helping others. You are accurate and persistent in your work. Good communication and writing skills in English are needed and you work well with others. We hope you are excited of getting new tasks and developing yourself.
We wish that you have:
- A Bachelor’s degree in Life Sciences or other related discipline
- 2 years of relevant laboratory experience
- Experience working with mammalian cells and performing laboratory based Immune cellular assays
- Excellent communication, interpersonal, and organizational skills
- Possess basic IT skills, preferably experience with Microsoft Office, Graph Pad Prism and Flowjo
- Flow cytometry and sample preparation for single cell RNA sequencing experience is an advantage
- Industry experience is an advantage, but not a requirement
Additional information
Please send your CV and cover letter in English by 29th October 2023. We may start processing applications already during the application period, so please submit your application as soon as possible.
For further information, please contact Dr Anil Thotakura, Head of Immuno-Oncology, +358 50 966 7229. Best time to contact: 18th October 14:00 to 15:00 and 24th October 9:30 to 11:00 am.
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person.
Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.
15.10.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3727036129
About the job
Are you systematic, organized and take pride in being meticulous even under time pressure? Are you interested in working in the core of production at the forefront of life sciences and healthcare? If you answered ”yes!”, keep reading!
Blueprint Genetics, a Quest Diagnostics company is a leading clinical genetic testing company aspiring to bring world-class genetic knowledge to mainstream healthcare. We want to improve the lives of individuals and families impacted by inherited diseases. Our Production Services Team is looking for an Accessioning Specialist to work at our sample reception in our Keilaniemi office in Espoo, Finland.
Job Description
As an accessioning specialist your primary task will be to review orders, perform sample reception and specimen accessioning and record sample information into our system. You confirm that samples arriving at our laboratory comply with our sample requirements and review the enclosed paperwork. You use your knowledge of our products and your background in life sciences to make sure the test choices are optimal for the customer’s needs. You take pride in being meticulous as your work as an accessioning specialist is very detail-oriented and guided by precise guidelines. Problem-solving skills are needed to apply those guidelines in practice for the diverse patient cases that are received by our laboratory. On a daily basis, you will have a chance to work closely with other awesome experts at Blueprint Genetics from customer support to clinical genetics.
Your Main Responsibilities Will Be
- Reviewing orders, sample reception, and accessioning
- Recording sample information in the Laboratory Information System
- Performing quality control for clinical samples and clinical records
- Examining requisitions to ascertain acceptability against established criteria
- Investigating incomplete or unacceptable submissions
- Organizing samples and paperwork per established protocol
Our ideal candidate
We hope that you are highly motivated to work in specimen accessioning and eager to learn more about our production processes. You take pride in having superior attention to detail and you are comfortable with following routines and processes. In order to ensure an uninterrupted production chain, our team works in shifts, including evenings and occasionally also on weekends. We value flexibility and the ability to work under pressure, as at times the work can get hectic due to a high level of incoming samples. Last but not least, we aspire to find a person who fits the inclusive, low-hierarchy, and positive culture of Blueprint Genetics!
Our Ideal Team Member Has
- A Vocational or Bachelor’s degree preferably in life sciences or relevant field
- Any specialization and/or prior experience in medical genetics and laboratory accessioning is an asset
- Good proficiency in written and verbal communication skills in English. Finnish skills are seen as an advantage
- Superior attention to detail, and a systematic approach to work
- Good computer and data entry skills
- Enthusiasm to learn more about our products and production processes, and a passion to develop them further
- The ability to work in shifts (including evenings and occasional weekends)
What We Offer
- The opportunity to work for a company that makes a real difference – Blueprint Genetics has a clear and motivating purpose to improve the lives of patients and families affected by inherited diseases
- A positive, open, and international work environment with great people from different fields of expertise. We are a team of close to 300 experienced professionals, who collaborate to drive genetic knowledge forward
- As an accessioning specialist you’ll become part of our crew of 20 dedicated, supportive and diverse professionals. You’ll be at the frontline of our operations and playing a key role in ensuring our production process runs smoothly and targets are met
- Employee benefits such as participation to performance-based bonus payment system, extensive occupational healthcare with Heltti, sports, culture & wellbeing benefit, team events & office parties.
How To Apply
Please submit your application and CV latest on Oct 22nd, 2023. Interviews will start during the application period. We hope you join our team as soon as possible. The position is permanent and full-time.If you have any further questions about the position, you can turn to our Production Services Manager Iida Heikkilä by email: iida.heikkila@blueprintgenetics.com or by mobile +358 40 5899 017 on Tuesday October 3rd between 10 and 11 am EET and Thursday October 5th between 2 and 4 pm EET.
Who We Are
We are a specialty genetics and bioinformatics company focused on providing genetic testing for inherited diseases. We are based in Helsinki, with a customer base spanning over 70 countries. www.blueprintgenetics.comBlueprint Genetics is a Quest Diagnostics company. Quest Diagnostics is the world’s leading provider of diagnostic information services. www.questdiagnostics.comWe are changing diagnostics by providing accessible and actionable genetic knowledge in all medical specialties. Our mission is to support healthcare professionals around the world in providing the best care for patients and families with rare inherited diseases. We do that by delivering answers using fast, affordable, and comprehensive genetic diagnostics.
Posted on Sep 26, 2023.
15.10.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3733198082
About the job
The University of Oulu is one of the biggest and most multidisciplinary universities in Finland. We create new knowledge and innovations that help to solve global challenges. We offer you an international and inspiring working environment where you are given responsibility and can use your skills, develop yourself and do work that matters. Our flexible and family-friendly workplace makes it easy for you to balance work and leisure. The University of Oulu is ranked in the top 3% of the world´s universities.
Applications are invited for full-time
Postdoctoral Researcher
position for a maximum of four years, starting at the earliest on 01.01.2024 in a Biocenter Oulu research project ”The ECM control of the prostate cancer genome” led by Professors Aki Manninen and Gong-Hong Wei at the Disease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine.
Description Of The Project
The aim of our project is to characterize the molecular mechanisms by which the tumor microenvironment regulates the genome organization and epigenetic status of prostate cancer (PCa) cells. A specific focus will be put on the role of α6β4-integrins in mediating mechanical regulation of chromatin organization in the nucleus. The function of super enhancer regions harboring multiple PCa risk-associated genetic variations will be investigated in order to better understand how the region contributes to genomic regulation of PCa-promoting transcriptional programs.
The postdoctoral researcher will work together with our multinational team and will learn to utilize 3D cell culture models, prostate cancer patient-derived organoids, xenograft-mouse models, advanced microscopy techniques, viral CRISPR/Cas9-based genomic engineering as well as other molecular cell biology methods and functional genetics/genomics/bioinformatics approaches.
What we offer?
- Exciting research project and excellent multidisciplinary research environment
- The support of an experienced and enthusiastic team and broad scientific network where you can share your expertise and grow as an expert.
- Development and career options of the big organization. FBMM is highly international (~50% of the roughly 200 employees at the faculty are international). Biocenter Oulu and the FBMM has put a great effort towards building a cutting-edge research infrastructure that includes state-of-the-art instrumentation for imaging, gene-modified mice, X-ray crystallography, and quantitative biochemistry. The Faculty has extensive collaborative national and international networks including Biocenter Finland and the ESFRI projects Instruct, EuroBioimaging, and Infrafrontier.
- Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits.
- Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
- Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu.
- We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
- Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.
What we expect from you?
- We are looking for ambitious, highly motivated candidates who have enthusiasm and ability to work hard both independently and as a team member to tackle challenging problems to achieve common goals.
- Doctoral degree in a relevant field (must have been completed by 31.12.2023)
- Documented experience in experimental research is required; previous experience in cell biology, cancer genetics, functional genomics or mouse model is appreciated but not essential
- Ability to fluently communicate in English. Both spoken and written English skills are required.
- All our researchers also teach. For postdoctoral fellows this typically means teaching/supervision in practical laboratory courses for undergraduates, supervision of doctoral students/undergraduates in the laboratory. Could also include lecturing.
Salary
The position is fixed-term for maximum of 4 years as of 01.01.2024 or as soon as possible thereafter.
The salary will be based on the levels 5-6 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 3600-4200 € per month (before taxes).
A trial period of 6 months is applied in the position.
How to apply?
Interested? If yes, please apply by 01.11.2023 (23:59 Finnish local time) through our recruitment system.
The application should be written in English and include the following:
- Cover letter shortly describing your motivation to apply for this position
- CV following the guidelines of the Finnish Advisory Board on Research Integrity
- List of publications, following the guidelines of the Academy of Finland
- Certificates/Diplomas
- Contact information of two persons available for recommendation
The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview. All applicants will be notified during the selection process.
Contact Information
If you have any further questions, please contact Prof. Aki Manninen, email: aki.manninen(at)oulu.fi or Prof. Gong-Hong Wei, email: gonghong.wei(at)oulu.fi
Työsopimuksen voimassaolo: määräaikainen yli 6 kuukautta | Työsuhteen luonne: kokoaikainen | Paikkojen lukumäärä: 1 | Työllisyysaste: 100 % | Paikkakunta: Oulu | Maakunta: Pohjois-Pohjanmaa | Maa: Finland | Ilmoitusnumero: 2023/477 | Yhteys: Aki Manninen +358505550787, | Julkaistu: 2023-10-04 | Haku päättyy: 2023-11-01
Posted on Oct 4, 2023.
15.10.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3733197351
About the job
The University of Oulu is one of the biggest and most multidisciplinary universities in Finland. We create new knowledge and innovations that help to solve global challenges. We offer you an international and inspiring working environment where you are given responsibility and can use your skills, develop yourself and do work that matters. Our flexible and family-friendly workplace makes it easy for you to balance work and leisure. The University of Oulu is ranked in the top 3% of the world´s universities.
Applications are invited for two full-time
Doctoral researcher
positions for a maximum of four years, starting at the earliest on 01.01.2024 in a Biocenter Oulu research project ”The ECM control of the prostate cancer genome” led by Professors Aki Manninen and Gong-Hong Wei at the Disease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine.
Description Of The Project
The aim of our project is to characterize the molecular mechanisms by which the tumor microenvironment regulates the genome organization and epigenetic status of prostate cancer (PCa) cells. A specific focus will be put on the role of α6β4-integrins in mediating mechanical regulation of chromatin organization in the nucleus. The function of super enhancer region harboring multiple PCa risk-associated genetic variants will be investigated in order to better understand how the region contributes to genomic regulation of PCa-promoting transcriptional programs.
The doctoral researchers will work together with our multinational team and will learn to utilize 3D cell culture models, prostate cancer patient-derived organoids, xenograft-mouse models, advanced microscopy techniques, viral CRISPR/Cas9-based genomic engineering as well as other molecular cell biology methods and functional genetics/genomics approaches.
What we offer?
- Exciting research project and excellent multidisciplinary research environment
- The support of an experienced and enthusiastic team and broad scientific network where you can share your expertise and grow as an expert.
- Development and career options of the big organization.
- Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits.
- Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
- Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu.
- We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
- Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.
What we expect from you?
- A successful candidate is highly motivated and a curious mind
- You must possess a Master’s degree or an equivalent degree (e.g. licentiate) preferably in molecular cell biology, biochemistry and molecular medicine, genetics, functional genomics or similar. Degree must have been completed with good grades by 31.12.2023.
- All our researchers also teach. For Doctoral Researchers this typically means teaching/supervision in practical laboratory courses for undergraduates.
- Successful candidate is expected to be collaborative and have good communication skills. Ability to pursue independent research and to communicate and write in English is also expected.
The selected candidates will carry out their doctoral studies in the Health and Biosciences Doctoral Programme of the University of Oulu Graduate School (UniOGS) and must meet the minimal requirements to receive doctoral study rights as defined in UniOGS requirements.
Salary
The positions are fixed-term for maximum of 4 years as of 01.01.2024 or as soon as possible thereafter.
The salary will be based on the levels 2-4 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 2300-2600 € per month (before taxes).
A trial period of 6 months is applied in the position.
How to apply?
Interested? If yes, please apply by 01.11.2023 (23:59 Finnish local time) through our recruitment system.
The application should be written in English and include the following:
- Cover letter shortly describing your motivation to apply for this position
- CV following the guidelines of the Finnish Advisory Board on Research Integrity
- Certificates/Diplomas
- Contact information of two persons available for recommendation
The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview. All applicants will be notified during the selection process.
Contact Information
If you have any further questions, please contact Prof. Aki Manninen, email: aki.manninen(at)oulu.fi or Prof. Gong-Hong Wei, email: gonghong.wei(at)oulu.fi
Työsopimuksen voimassaolo: määräaikainen yli 6 kuukautta | Työsuhteen luonne: kokoaikainen | Paikkojen lukumäärä: 2 | Työllisyysaste: 100 % | Paikkakunta: Oulu | Maakunta: Pohjois-Pohjanmaa | Maa: Finland | Ilmoitusnumero: 2023/474 | Yhteys: Aki Johannes Manninen +358505550787, | Julkaistu: 2023-10-04 | Haku päättyy: 2023-11-01
Posted on Oct 4, 2023.
15.10.2023 | Avoimet työpaikat
Lagerlöf Lab at Umeå University in Sweden is seeking a postdoctoral fellow excited to study how the brain regulates food intake. Our lab has fun, is supportive and loves the brain! It’s a position for 2 years where we have funding to extend it for longer. Several projects are available and candidates with different backgrounds are encouraged to apply. We want to support your career and help you take the next step towards your goals. Contact PI olof.lagerlof@umu.se or apply directly through https://tinyurl.com/n8unycet.
16.9.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3702460183
About the job
Eliisa Kekäläinen’s research group “Inborn and acquired immunodeficiencies” at the Translational Immunology Research Program at University of Helsinki, Faculty of Medicine invites applications for the position of
POSTDOCTORAL RESEARCHER
Our research group focuses on the human thymus which produces key immune cells, the T cells. We 1) evaluate and develop methods to better measure thymopoiesis, 2) study how thymopoiesis and the thymus itself is affected by viral infections, and 3) aim to understand how and why certain autoimmune diseases, such as myasthenia gravis, develops. We use thymic tissue samples from both immunologically healthy individuals and patients with cutting edge techniques including thymic organ cultures and different multi-dimensional single-cell methods to dissect the normal and pathological processes in the thymus. We are seeking for a motivated post-doctoral researcher to work on Research Council of Finland – funded project.
Qualifications
Applicants with a doctoral degree and strong background in immunology or other relevant life science fields who are interested in working in an inter-disciplinary environment are particularly encouraged to apply. Applicant must be able to work independently and have good communication skills in English. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.
The person we are looking for has:
- effective communication and collaboration skills
- proven track record in designing and executing experimental science
- motivation and determination to learn (more) immunology
Furthermore, if you have experience with the topics below, we would love to hear about your
- supervision experience
- working with tissue samples or organoid cultures
- experience in flow cytometry, single-cell omics, CRISPR-Cas or immunohistochemistry
What We Offer
The appointment will be initially for two years starting from January 2024 (possibility to start earlier or later if needed). Trial period of six months will be applied. The monthly gross salary will be appr. 3200-3600 € per month depending on the appointee’s qualifications and experience. In addition, University of Helsinki offers comprehensive services to its employees, including occupational health care and opportunities for professional development. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .
We offer you on top of these benefits an opportunity to explore and learn in a team that shares a passion for immunology. The team’s well-being is top priority in our laboratory.
How To Apply
Please submit your application as a single PDF file containing your CV, a publication list where you describe your own role in the publications that you consider the most relevant for the position, and two letters of reference. The application will be submitted through the University’s electronic recruitment system by clicking “Apply now” link. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi. The deadline for applications is 30 October 2023. Applications will be considered on a rolling basis until a suitable candidate is found.
For further information on the position, please contact Eliisa Kekäläinen (eliisa.kekalainen(at) helsinki.fi).
For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk (at) helsinki.fi).
Selected publications from Kekäläinen lab:
Hetemäki I, Kaustio M, Kinnunen M, Heikkilä N, Keskitalo S, Nowlan K, Miettinen S, Sarkkinen J, Glumoff V, Andersson N, Kettunen K, Vanhanen R, Nurmi K, Eklund KK, Dunkel J, Mäyränpää MI, Schlums H, Arstila TP, Kisand K, Bryceson YT, Peterson P, Otava U, Syrjänen J, Saarela J, Varjosalo M, Kekäläinen E. Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells. Sci Immunol. 2021 Nov 26;6(65):eabe3454. doi: 10.1126/sciimmunol.abe3454.
Sarkkinen J, Dunkel J, Tuulasvaara A, Huuskonen A, Atula S, Kekäläinen E, Laakso SM. Ectopic germinal centers in the thymus accurately predict prognosis of myasthenia gravis after thymectomy. Mod Pathol. 2022 Sep;35(9):1168-1174. doi: 10.1038/s41379-022-01070-2.
Kleino I, Nowlan K, Kotimaa J, Kekäläinen E. Optimising protein detection with fixable custom oligo-labelled antibodies for single-cell multi-omics approaches. Biotechnol J. 2022 Jun;17(6):e2100213. doi: 10.1002/biot.202100213.
Nguyen NA, Huang X, Cabrera LE, Pekkarinen PT, Nowlan K, Strandin T, Kantele A, Vapalahti O, Heinonen S, Kekäläinen E. A comprehensive assessment of four whole blood stabilizers for flow-cytometric analysis of leukocyte populations. Cytometry A. 2023 Apr;103(4):313-324. doi: 10.1002/cyto.a.24700. Epub 2022 Nov 1. PMID: 36279192.
Lusila P, Toivonen A, Jarva H, Vettenranta K, Lehtimäki S, Kekäläinen E. FASCIA Method in the Assessment of Lymphocyte Mitogen Responses in the Laboratory Diagnostics of Primary Immunodeficiencies. J Clin Immunol. 2023 Apr;43(3):653-661. doi: 10.1007/s10875-022-01417-z.
The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.
The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.
Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.
16.9.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3706052115
About the job
INVITATION FOR APPLICATIONS
Postdoctoral researcher
We are looking for a skilled postdoctoral fellow with a background in neuroscience and/or human stem cell based neuronal models at the Institute for Molecular Medicine Finland FIMM , Helsinki Institute of Life Science, HiLIFE in the research groups of Professor Aarno Palotie ( Research Group Palotie ) and Dr. Olli Pietiläinen ( Research Group Pietiläinen ). The position is part of a research program that aims to discover biological mechanisms in schizophrenia and related neuropsychiatric disorders. The program bridges multidisciplinary group of researchers in the interface of genetic discoveries and multi-omic molecular biology using cell collections from over 6000 sequenced participants. The project combines state-of-art functional genomics and experimental cell biology approaches in human stem-cell derived neuronal models to discover how genetic risk factors identified in the disorders mediate their causative effects in human cells. The Pietiläinen laboratory is based at the Neuroscience Center and has close links with the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard ( https://www.broadinstitute.org/stanley ). The Pietiläinen group is located at the Meilahti biomedical campus in Helsinki and is closely linked with research groups at the HiLIFE Institute for Molecular Medicine https://www.helsinki.fi/en/hilife-fimm (HiLIFE-FIMM) and the Faculty of Biological and Environmental Sciences https://www.helsinki.fi/en/faculty-of-biological-and-environmental-sciences . HiLIFE-NC offers a inspiring environment to solve fundamental challenges of brain functions as part of the multidisciplinary HiLIFE infrastructure https://www.helsinki.fi/en/helsinki-institute-of-life-science at the university of Helsinki. In Pietiläinen group you will be part of a striving scientific community utilizing state of the art technologies in genomics and cell biology for scientific discoveries of the brain.
Role description:
We are seeking a postdoctoral researcher to work on a multidisciplinary project that utilizes human induce pluripotent stem cells (iPSC) to model cellular processes involved in neuropsychiatric disorders. The primary goal is to use known genetic risk variants to identify quantifiable cellular phenotypes that underlie neuropsychiatric disorders. To this end we apply high-throughput multiple omics approaches such RNA sequencing and proteomics that are complemented by experimental molecular cell biology approaches in the in vitro model systems, including cellular assays and gene editing techniques in isogenic cell lines. We are looking for a person for planning, conducting, and co-supervising molecular biology and cellular experiments in human iPSCs.
Key Requirements
We are looking for a highly motivated and creative person with a primary interest in molecular cell biology using human iPSC derived neuronal models to discover mechanisms in neurological disorders, and to work in multidisciplinary team of clinical, wet lab, and computational scientists. Candidates should have a PhD in neuroscience or molecular and cell biology with experience in iPSC derived neuronal models. We require previous experience and skills in cell culture, molecular cell biology, iPSC models, and neural differentiation. The ideal candidate will have experience in these areas, and an interest in translating genetic discoveries into functional biology. Any previous experience in analysing and processing genomic and omic data is considered an advantage. The position is available from September 2023 onwards, or earlier, if required. It is a two-year fixed-term position, with a possibility of extension. Trial period of 6 months will be applied.
The salary will be based on level 5 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance with the overall starting salary amounting to approximately 3600-4500 EUR per month, depending on the qualifications and previous relevant research experience of the candidate.
Please submit your application via the University of Helsinki Recruitment System by clicking the ‘Apply for the position button’ below. If you need support with the recruitment system, please contact recruitment@helsinki.fi.
Please attach the following documents to your application as a single PDF file:
- CV (including publications)
- cover letter (maximum 1 page) that details your past experience and motivation
- contact details of at least two references
The deadline for applications is September 29th, 2023. Interviews will be conducted either in person or online. For more information on the position, please contact Dr. Olli Pietiläinen (olli.pietilainen@helsinki.fi).
University of Helsinki
The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.
Helsinki Institute of Life Science
Helsinki Institute of Life Science (HiLIFE) is a new institute established in 2017 that supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.
Institute for Molecular Medicine Finland
The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki – a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community
HiLIFE -Neuroscience Center
The Neuroscience Center is an international research unit within Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki, a leading Nordic university with a strong commitment to life science research. The research focus of NC is on translational brain plasticity. We carry out research relevant for the human brain both in health and disease, and during development and aging, by applying versatile approaches and modern technology platforms. NC aims at making fundamental discoveries about brain functions and especially translate research findings into improvements in the treatment, prevention and diagnosis of psychiatric and neurological disorders. The research in NC spans across several scales from stem cell research and molecular neuroscience to systems and cognitive neuroscience in both animal and human models.The research groups of NC conduct research in neuroscience at the highest international level and actively apply the results for the benefit of the society. NC collaborates actively with other units of HiLIFE and faculties of the University of Helsinki, Helsinki University Central Hospital, and Neurocenter Finland.