Eliisa Kekäläinen’s research group “Inborn and acquired immunodeficiencies” at the Translational Immunology Research Program at University of Helsinki, Faculty of Medicine invites applications for the position of
POSTDOCTORAL RESEARCHER
Our research group focuses on the human thymus which produces key immune cells, the T cells. We 1) evaluate and develop methods to better measure thymopoiesis, 2) study how thymopoiesis and the thymus itself is affected by viral infections, and 3) aim to understand how and why certain autoimmune diseases, such as myasthenia gravis, develops. We use thymic tissue samples from both immunologically healthy individuals and patients with cutting edge techniques including thymic organ cultures and different multi-dimensional single-cell methods to dissect the normal and pathological processes in the thymus. We are seeking for a motivated post-doctoral researcher to work on Research Council of Finland – funded project.
Qualifications
Applicants with a doctoral degree and strong background in immunology or other relevant life science fields who are interested in working in an inter-disciplinary environment are particularly encouraged to apply. Applicant must be able to work independently and have good communication skills in English. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.
The person we are looking for has:
effective communication and collaboration skills
proven track record in designing and executing experimental science
motivation and determination to learn (more) immunology
Furthermore, if you have experience with the topics below, we would love to hear about your
supervision experience
working with tissue samples or organoid cultures
experience in flow cytometry, single-cell omics, CRISPR-Cas or immunohistochemistry
What We Offer
The appointment will be initially for two years starting from January 2024 (possibility to start earlier or later if needed). Trial period of six months will be applied. The monthly gross salary will be appr. 3200-3600 € per month depending on the appointee’s qualifications and experience. In addition, University of Helsinki offers comprehensive services to its employees, including occupational health care and opportunities for professional development. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .
We offer you on top of these benefits an opportunity to explore and learn in a team that shares a passion for immunology. The team’s well-being is top priority in our laboratory.
How To Apply
Please submit your application as a single PDF file containing your CV, a publication list where you describe your own role in the publications that you consider the most relevant for the position, and two letters of reference. The application will be submitted through the University’s electronic recruitment system by clicking “Apply now” link. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi. The deadline for applications is 30 October 2023. Applications will be considered on a rolling basis until a suitable candidate is found.
For further information on the position, please contact Eliisa Kekäläinen (eliisa.kekalainen(at) helsinki.fi).
For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk (at) helsinki.fi).
Selected publications from Kekäläinen lab:
Hetemäki I, Kaustio M, Kinnunen M, Heikkilä N, Keskitalo S, Nowlan K, Miettinen S, Sarkkinen J, Glumoff V, Andersson N, Kettunen K, Vanhanen R, Nurmi K, Eklund KK, Dunkel J, Mäyränpää MI, Schlums H, Arstila TP, Kisand K, Bryceson YT, Peterson P, Otava U, Syrjänen J, Saarela J, Varjosalo M, Kekäläinen E. Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells. Sci Immunol. 2021 Nov 26;6(65):eabe3454. doi: 10.1126/sciimmunol.abe3454.
Sarkkinen J, Dunkel J, Tuulasvaara A, Huuskonen A, Atula S, Kekäläinen E, Laakso SM. Ectopic germinal centers in the thymus accurately predict prognosis of myasthenia gravis after thymectomy. Mod Pathol. 2022 Sep;35(9):1168-1174. doi: 10.1038/s41379-022-01070-2.
Kleino I, Nowlan K, Kotimaa J, Kekäläinen E. Optimising protein detection with fixable custom oligo-labelled antibodies for single-cell multi-omics approaches. Biotechnol J. 2022 Jun;17(6):e2100213. doi: 10.1002/biot.202100213.
Nguyen NA, Huang X, Cabrera LE, Pekkarinen PT, Nowlan K, Strandin T, Kantele A, Vapalahti O, Heinonen S, Kekäläinen E. A comprehensive assessment of four whole blood stabilizers for flow-cytometric analysis of leukocyte populations. Cytometry A. 2023 Apr;103(4):313-324. doi: 10.1002/cyto.a.24700. Epub 2022 Nov 1. PMID: 36279192.
Lusila P, Toivonen A, Jarva H, Vettenranta K, Lehtimäki S, Kekäläinen E. FASCIA Method in the Assessment of Lymphocyte Mitogen Responses in the Laboratory Diagnostics of Primary Immunodeficiencies. J Clin Immunol. 2023 Apr;43(3):653-661. doi: 10.1007/s10875-022-01417-z.
The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.
The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.
Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.
We are looking for a skilled postdoctoral fellow with a background in neuroscience and/or human stem cell based neuronal models at the Institute for Molecular Medicine Finland FIMM , Helsinki Institute of Life Science, HiLIFE in the research groups of Professor Aarno Palotie ( Research Group Palotie ) and Dr. Olli Pietiläinen ( Research Group Pietiläinen ). The position is part of a research program that aims to discover biological mechanisms in schizophrenia and related neuropsychiatric disorders. The program bridges multidisciplinary group of researchers in the interface of genetic discoveries and multi-omic molecular biology using cell collections from over 6000 sequenced participants. The project combines state-of-art functional genomics and experimental cell biology approaches in human stem-cell derived neuronal models to discover how genetic risk factors identified in the disorders mediate their causative effects in human cells. The Pietiläinen laboratory is based at the Neuroscience Center and has close links with the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard ( https://www.broadinstitute.org/stanley ). The Pietiläinen group is located at the Meilahti biomedical campus in Helsinki and is closely linked with research groups at the HiLIFE Institute for Molecular Medicine https://www.helsinki.fi/en/hilife-fimm (HiLIFE-FIMM) and the Faculty of Biological and Environmental Sciences https://www.helsinki.fi/en/faculty-of-biological-and-environmental-sciences . HiLIFE-NC offers a inspiring environment to solve fundamental challenges of brain functions as part of the multidisciplinary HiLIFE infrastructure https://www.helsinki.fi/en/helsinki-institute-of-life-science at the university of Helsinki. In Pietiläinen group you will be part of a striving scientific community utilizing state of the art technologies in genomics and cell biology for scientific discoveries of the brain.
Role description:
We are seeking a postdoctoral researcher to work on a multidisciplinary project that utilizes human induce pluripotent stem cells (iPSC) to model cellular processes involved in neuropsychiatric disorders. The primary goal is to use known genetic risk variants to identify quantifiable cellular phenotypes that underlie neuropsychiatric disorders. To this end we apply high-throughput multiple omics approaches such RNA sequencing and proteomics that are complemented by experimental molecular cell biology approaches in the in vitro model systems, including cellular assays and gene editing techniques in isogenic cell lines. We are looking for a person for planning, conducting, and co-supervising molecular biology and cellular experiments in human iPSCs.
Key Requirements
We are looking for a highly motivated and creative person with a primary interest in molecular cell biology using human iPSC derived neuronal models to discover mechanisms in neurological disorders, and to work in multidisciplinary team of clinical, wet lab, and computational scientists. Candidates should have a PhD in neuroscience or molecular and cell biology with experience in iPSC derived neuronal models. We require previous experience and skills in cell culture, molecular cell biology, iPSC models, and neural differentiation. The ideal candidate will have experience in these areas, and an interest in translating genetic discoveries into functional biology. Any previous experience in analysing and processing genomic and omic data is considered an advantage. The position is available from September 2023 onwards, or earlier, if required. It is a two-year fixed-term position, with a possibility of extension. Trial period of 6 months will be applied.
The salary will be based on level 5 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance with the overall starting salary amounting to approximately 3600-4500 EUR per month, depending on the qualifications and previous relevant research experience of the candidate.
Please submit your application via the University of Helsinki Recruitment System by clicking the ‘Apply for the position button’ below. If you need support with the recruitment system, please contact recruitment@helsinki.fi.
Please attach the following documents to your application as a single PDF file:
CV (including publications)
cover letter (maximum 1 page) that details your past experience and motivation
contact details of at least two references
The deadline for applications is September 29th, 2023. Interviews will be conducted either in person or online. For more information on the position, please contact Dr. Olli Pietiläinen (olli.pietilainen@helsinki.fi).
University of Helsinki
The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.
Helsinki Institute of Life Science
Helsinki Institute of Life Science (HiLIFE) is a new institute established in 2017 that supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.
Institute for Molecular Medicine Finland
The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki – a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community
HiLIFE -Neuroscience Center
The Neuroscience Center is an international research unit within Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki, a leading Nordic university with a strong commitment to life science research. The research focus of NC is on translational brain plasticity. We carry out research relevant for the human brain both in health and disease, and during development and aging, by applying versatile approaches and modern technology platforms. NC aims at making fundamental discoveries about brain functions and especially translate research findings into improvements in the treatment, prevention and diagnosis of psychiatric and neurological disorders. The research in NC spans across several scales from stem cell research and molecular neuroscience to systems and cognitive neuroscience in both animal and human models.The research groups of NC conduct research in neuroscience at the highest international level and actively apply the results for the benefit of the society. NC collaborates actively with other units of HiLIFE and faculties of the University of Helsinki, Helsinki University Central Hospital, and Neurocenter Finland.
Bring the future of clinical diagnostics through genomic data analysis to hospitals and laboratories globally.
Many diseases that have historically been incurable or untreatable will become curable or even preventable in the future due to increased understanding of our genomic data. Solving biological problems from this perspective is one of humanity’s greatest challenges. Do you want to play a role in enabling that change?
Responsibilities
As an Application Scientists your main responsibility is to demonstrate the capabilities and benefits of Euformatics software to customers as well as provide technical support and consultation to them. From assisting in the design and implementation of customer workflows and analysis pipelines to provide training and education to customers on the use of Euformatics tools, you will be responsible for building strong relationships with existing and potential customers and channel partners around the world taking ownership of their customer journey and success with us.
You will collaborate with cross-functional teams, including Product Development, Sales, and Marketing, to drive product adoption and customer satisfaction. Staying current on industry trends and new technologies in human genetics is valued. We are growing rapidly, and so is the number of our distributors and customers – this is your chance to play your part in making genomic analysis a routine part of every diagnosis.
You could be speaking with a laboratory director in a university hospital in the Philippines in the morning or catching-up with a customer in South America to ensure they are getting the most out of our products. Depending on your background, skills and experience you will be primarily responsible for one region in the world complemented by some custom-picked markets of interest.
You will work with your colleagues to maintain the Euformatics customer base, and maintain a strong, long-lasting relationship with them.
Qualifications
You are someone who is at ease in front of customers and a pro with words. Our customers are located all around the world, and we work in English, so a good working knowledge of English is crucial and fluency in other European languages is considered valuable.
You have a strong understanding in the field of genetics and molecular biology, or can demonstrate from previous experience that you are able to learn complex and new ideas quickly and effectively to be able to discuss with customers.
You understand the value of and can demonstrate experience of building trust with key stakeholders and are able to take initiative to solve customer problems.
You ideally have a doctoral degree and experience in a customer support role, but if you can convince us that your combination of skills and experience are the right fit then we are more interested in that than a degree. Most importantly, we value the priority and speed to keep customers satisfied topped with supporting your colleagues.
Work environment
We play the infinite game here at Euformatics. And occasionally some ping pong as well. In order to succeed in a complex and difficult field we need to work with people that commit to our mission and are in this for the long term. We are looking for people that want to make a difference and have the drive to make a long-lasting change. If this resonates with your ambition, please get it touch. We would love to hear from you!
Meille tärkeintä on aina ihminen. Potilaat, joiden elämänlaatua ja toimintakykyä hoitomme tukevat. Terveydenhuollon ammattilaiset, joille kehitämme lääketieteen huippua edustavia ratkaisuja. Työntekijät, joille tarjoamme merkityksellistä työtä.
AbbVie on osaavien ihmisten yhteisö. Sinä tuot siihen oman arvokkaan panoksesi ja saat tilaisuuden oppia muilta huippuammattilaisilta. Yhteisöllinen yrityskulttuurimme hyväksyy ihmiset yksilöinä ja tukee jokaisen henkilökohtaista kehittymistä.
Onnistumisestamme työyhteisönä kertoo omalta osaltaan sijoittumisemme vuosi vuoden jälkeen parhaiden joukkoon Great Place to Work -tutkimuksessa.
Nyt etsimme Lääketieteelliselle osastollemme Sinua asiakaslähtöinen, kokenut
MEDICAL ADVISOR
Vastuullasi on tuottaa ja jakaa lääketieteellistä tietoa sekä antaa tieteellistä tukea niin ulkoisille kuin sisäisille asiakkaillemme. Toimit dermatologian ja reumatologian terapia-alueilla vastaten psoriaattisten sairauksien (iho- ja nivelpsoriaasin) portfoliostamme. Olet tiiviisti yhteydessä asiakkaisiimme ja rakennat kontakteja kyseisten terapia-alueiden asiantuntijoihin Suomessa. Toimit yhteistyössä AbbVien tiimin ja terveydenhuollon ammattilaisten kanssa hoitokäytäntöjen parantamiseksi. Varmistat pysyväsi alan tuoreimman tiedon tasalla seuraamalla tieteellisiä julkaisuja sekä osallistumalla kongresseihin ja seminaareihin. Jaat tietoa ja koulutat sekä sisäisiä että ulkoisia sidosryhmiä tuoreesta tutkimustiedosta vastuualueellasi. Ymmärrät modernin Medical Affairs -työskentelyn pääpiirteet ja olet halukas rakentamaan uusia yhteistyötapoja sekä kehittämään itseäsi ja tiimisi toimintaa alati muuttuvassa toimintaympäristössä. Työskentelet tiiviissä yhteistyössä lääketieteellisen osaston kollegojen, myynti- ja markkinointiosaston sekä Market Accessin kanssa. Raportoit Immunologian Head of Medical Affairsille.
Odotamme sinulta kokemusta lääkealalta sekä jatkuvasti muuttuvan lääkealan ympäristön tuntemusta. Tehtävä edellyttää lääketieteellistä, luonnontieteellistä tai muuta soveltuvaa ylempää korkeakoulututkintoa sekä vahvaa tieteellistä orientaatiota. Taustaltasi voit olla esimerkiksi lääkäri, proviisori tai biotieteiden asiantuntija. Tieteellinen jatkokoulutus on edellytys tehtävässä menestymiselle. Dermatologian ja/tai reumatologian tuntemus katsotaan eduksi. Itsenäisen ja ennakkoluulottoman työskentelyn ohella tarvitset vahvoja vuorovaikutus- ja tiimityöskentelytaitoja sekä valmiutta toimia matriisiorganisaatiossa. Oleellisen tiedon hahmottaminen alan tutkimusartikkeleista ja kirjallisuudesta sekä tiedon selkeä ja ymmärrettävä kommunikointi sekä suomeksi että englanniksi mahdollistavat työssä menestymisen. Olet kiinnostunut työskentelemään kaupallisessa ympäristössä ja vaikuttamaan potilaiden hoitoon yhteistyössä alan asiantuntijoiden kanssa. Olet parhaimmillasi uusien mahdollisuuksien edessä.
Tarjoamme sinulle laaja-alaisen tehtävän, jossa pääset vaikuttamaan vastuullisella ja merkityksellisellä toimialalla osana menestyvää kansainvälistä yritystä. Tueksesi saat osaavat kollegat ja dynaamisen työyhteisön. Tuemme oppimista ja tarjoamme mahdollisuuden kehittyä ja kehittää osaamista työssäsi.
Kiinnostuitko? Lisätietoja tehtävästä antaa Piia Vehviläinen, Head of Medical Affairs Immunology, 5.9. klo 11-12, 12.9. klo 11-12:30 ja 15.9. klo 12-13, puh. 050 593 5502. Voit hakea tehtävään viemällä CV:si ja hakemuksesi rekrytointijärjestelmäämme palkkatoiveella varustettuna viimeistään 17.9.2023 mennessä.
AbbVie on yksi maailman suurimmista lääkeyrityksistä, joka kehittää hoitoja vakaviin sairauksiin, keskittyen immunologisiin ja neurologisiin sairauksiin, onkologiaan ja hematologiaan sekä silmäsairauksiin. Tavoitteemme on parantaa vakavien sairauksien kanssa elävien ihmisten elämänlaatua. Terveydenhuollon ammattilaisille tavoitteenamme on tarjota lääkeluokkansa parhaita tai uusia vaikutusmekanismeja hyödyntäviä ratkaisuja. Haluamme olla lääkealan paras ja kiinnostavin työpaikka. Suomessa työntekijöitä on noin 100 ja toimistomme sijaitsee Helsingin Pasilassa. Potilaskeskeinen ajattelumme kiteytyy mottoomme ’Aina ihminen’.
AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.
Doctoral programme in Microbiology and biotechnology, salaried doctoral researcher position
Doctoral researchers for different scientific fields
The University of Helsinki doctoral programmes invite applications for doctoral researchers starting from 1 January 2024 for a 1–4 year period. The university’s doctoral researchers, supervised by top-class researchers, carry out their research as part of an international academic community.
Position Description
The duties of a doctoral researcher are to work on their doctoral thesis and to complete the doctoral studies determined by the curriculum of each doctoral programme. The duties may also include teaching and other tasks for up to 5 % of the annual working time. The duration of the employment contract depends on the phase of the appointee´s thesis and starts with a trial period of six months.
The University of Helsinki offers:
The chance to work in an international, multidisciplinary research community
Excellent research infrastructure and support services
Occupational health service and other personnel benefits
A competitive salary
The salary for doctoral researchers at the beginning of their dissertation work is usually 2300-2650€ per month. As work on the dissertation progresses, the demands level of the salary rises. Salaries for doctoral researcher positions are based on level 2–4 of the job requirement scheme for teaching and research personnel in the salary system of Finnish universities. In addition, the doctoral researcher will be paid a salary component based on personal work performance.
The University of Helsinki Doctoral School has 33 doctoral programmes. The University awards some 500 doctoral degrees annually.
Qualifications
Applications are evaluated based on the quality of the research plan, available supervision arrangements, and the ability and motivation, as demonstrated through previous studies, academic performance, or other previously acquired knowledge and experience, to pursue the doctoral degree according to the research plan and the accompanying study plan. The research plan must fit the research profile of the doctoral programme.
The appointee must obtain the right to pursue a doctoral degree at the University of Helsinki during the probationary period. It is possible to start the employment relationship only after the degree (higher university degree or equivalent), which makes you eligible for doctoral studies, has been completed and obtained.
Doctoral researchers selected for the positions are employed by the University of Helsinki and are expected to reside in Finland while employed by the University of Helsinki. Each employment is placed in a suitable Faculty, a unit within a Faculty, or an Independent Institute.
The research work or part of it may be carried out outside University of Helsinki, for example in a state research institute, company, or other organization in Finland, but the employment and academic supervision are based in the University of Helsinki. Temporary research-based visits abroad are possible.
Interested in the position?
The application deadline is 14.9.2023. Applicants will be informed of decisions in December 2023.
Acquaint yourself with the application instruction from this link: University-funded doctoral researcher positions and especially the doctoral programme specific instructions .
The University of Helsinki is committed to promoting equality and preventing discrimination in all its operations. We encourage and welcome applications from people of all backgrounds.
Working for the world
Science has the power to change the world. Join one of the best research universities in the world – an international community united through bold thinking, science, research, and learning, with over 30,000 students and 8,000 employees.
We are defined by our multidisciplinary approach. This, combined with a dedication for cross-border collaboration, gives us our potential to find real solutions and build hope for a better, more sustainable future.
We are united by our values – truth, bildung, freedom, and inclusivity – as well as our passion for work that truly matters.
Join us: WORK FOR THE FUTURE – WORK FOR THE WORLD. #helsinkiunicareers
Aalto University is where science and art meet technology and business. We shape a sustainable future by making research breakthroughs in and across our disciplines, sparking the game changers of tomorrow and creating novel solutions to major global challenges. Our community is made up of 13 000 students, 400 professors and close to 4 500 other faculty and staff working on our dynamic campus in Espoo, Greater Helsinki, Finland. Diversity is part of who we are, and we actively work to ensure our community’s diversity and inclusiveness. This is why we warmly encourage qualified candidates from all backgrounds to join our community.We are now looking for a
Tenure Track or Tenured Professor, Enzyme Technology
The position is to be filled at any level of the Aalto University tenure track system (Assistant, Associate or Full Professor). The position is full-time and depending on the positioning on the tenure track, either on fixed or permanent term.An increased use of biotechnical production methods, the efficient use of renewable raw materials, and a transfer to green processes in industry will place new demands on enzymatic biocatalysts. Enzymes are central tools in the utilization of bio-based raw materials, and in the development and manufacturing of materials and products using bio-based components. Enzyme technology will also continue to impact fields such as recycling and upgrading of raw materials, novel food and feed, protein technology, surface functionalization, crosslinking, and fine chemicals. A wide understanding of structure-function relations in proteins and the fields of applications are needed. Tools such as structural analysis, protein engineering, recombinant production, molecular modelling, directed evolution are important for a successful research program. An understanding of advanced screening methods, the use of genomic data, and artificial intelligence/machine learning will further advance the field.As a professor at the Department of Bioproducts and Biosystems (http://bio2.aalto.fi/en/), you will establish and lead your own research group. You will be responsible for education in the field of enzyme technology and participate in biotechnology teaching at BSc, MSc, and doctoral level.
Scientific Environment
The department of Bioproducts and Biosystems (BIO2) (http://bio2.aalto.fi/en/), one of the three departments in the School of Chemical Engineering, has an internationally leading reputation in basic and applied research for the conversion of natural resources to chemicals and advanced materials. It is one of the leading European research and higher education institutions in the field of sustainable chemistry and engineering for the utilization of renewable resources. BIO2 aims to contribute to the development of novel solutions to move towards sustainable primary production and processing systems that can produce materials with less environmental impact and reduced greenhouse gas emissions. At the BIO2 department, the enzyme technology professor will have numerous opportunities to link feedstocks and processing to the utilization and products of lignocellulose and other industries. There are excellent facilities for protein research, recombinant protein technology, and bioprocessing for enzyme production. Within bioscience, the department has research in bioprocess engineering, molecular biotechnology, microbial physiology, metabolic engineering, synthetic biology, biomolecular, and bio-hybrid materials.
Your Experience And Ambitions
We are looking for applicants who have:
a doctoral degree in biochemistry, molecular biology, chemistry, microbiology, or another related field
a research background supporting the topic of enzyme technology
relevant teaching experience
a strong publication record
experience in international collaborations and projects
documented experience in obtaining research funding
Applicants with an industrial background in addition to a scientific career are very welcome. The applicants will be reviewed on the basis of their research work, teaching and academic leadership and activity in the scientific community.
What We Offer
We offer a research-oriented environment, with highly functional laboratories and research infrastructure (http://www.bioeconomyinfra.fi/). The research groups form a collaborative environment that supports the development of bio-based solutions and provides beneficial interactions and common research topics.We offer the possibility to work within a well-resourced learning community where the students are rigorously selected and highly motivated. This results in an unusually interactive and intellectually challenging atmosphere.Aalto University provides its employees with occupational health care services and retirement benefits. Finland is a healthy and safe living environment, offering many excellent state-subsidized services including affordable day care, free schools and universities, which are consistently ranked among the best in the world. For more information about living and working in Finland, see https://www.aalto.fi/en/careers-at-aalto/for-international-staff .The salary is determined based on the applicant’s experience and qualifications. Activities of the department are located in the Otaniemi campus of Aalto University in Espoo (Helsinki metropolitan area).
Tenure track in Aalto University
The position is a tenure track position. Individuals appointed to the tenure track have the opportunity to conduct research and/or artistic work and teach in order to build academic merits towards qualifying for an appointment to a tenured position.Since 2010, the tenure track has attracted a wide range of international applicants, giving Aalto University the possibility of recruiting top experts and young talent to join the Aalto University community. Throughout their careers, those in the tenure track system are expected to conduct and supervise artistic/scientific research and/or artistic/design work, to provide related academic education, contribute to developing their field or discipline, as well as contribute to academic service the university and beyond in the society. For more information on the tenure track system of Aalto University, please see https://www.aalto.fi/en/tenure-track.
Ready to apply?
If you want to join our community, please submit your application no later than 31.8.2023 through our recruiting system by using the ”Apply” link.If you are an employee at Aalto, please note that you should apply for the position via our internal system Workday. Please use your existing Workday user account.To apply, please share the following application materials with us in English and in PDF form:
Application letter
Curriculum Vitae – please use the template recommended by The Finnish Advisory Board on Research Integrity. Please also include names and contact information for references.
List of publications (with 10 most relevant publications regarding this position highlighted)
Research portfolio – a concise reflection on the merits and highest achievements in research (max 2 pages) and a description of past research and plans for future research (max 5 pages)
Teaching portfolio according to Aalto University’s guidelines – see Teaching portfolio guidelines for candidate
Aalto University uses external reviews to support the evaluation of applicants during the recruitment process. The most suitable applicants will be invited to visit the department of Bioproducts and Biosystems and deliver teaching demonstrations.General instructions for applicants including evaluation criteria, language requirements and guidelines for compiling your CV are given at https://www.aalto.fi/en/tenure-track/interested-in-joining-our-tenure-track.Applicants are also encouraged to provide their Researcher ID (www.researcherid.com) or corresponding information in the application.Want to know more about us and your future colleagues? You can watch these videos: https://www.youtube.com/watch?v=5k_og_6zUJQ and https://www.youtube.com/watch?v=dUfEGVM-ZP8&feature=youtu.be
Further information
For additional information about the position, please contact Professor Markus Linder, or in questions related to the recruitment process, please contact HR Partner Noora Katisko (firstname.lastname@aalto.fi).
About Finland
Finland is a great place for living with or without family – it is a safe, politically stable and well-organized Nordic society. Finland is consistently ranked high in quality of life and was just listed again as the happiest country in the world: https://worldhappiness.report/news/its-a-three-peat-finland-keeps-top-spot-as-happiest-country-in-world/. For more information about living in Finland: https://www.aalto.fi/en/services/why-finland,Finland is an R&D oriented high-tech society committed to increase annual R&D input to 4% of GDP. Finland has been the forerunner in the development and production of industrial enzymes and within forest biotechnology. In addition to these major commercial established activities, novel industrial bioprocesses are currently being developed e.g., within cellular food, circular economy and fuel compounds in research organizations and private companies. This results in continuing need for bioprocess professionals and enables industry related projects.___________________________________Aalto-yliopistossa tiede ja taide kohtaavat tekniikan ja talouden. Rakennamme kestävää tulevaisuutta saavuttamalla läpimurtoja avainalueillamme ja niiden yhtymäkohdissa. Samalla innostamme tulevaisuuden muutoksentekijöitä ja luomme ratkaisuja maailman suuriin haasteisiin. Yliopistoyhteisöömme kuuluu 13 000 opiskelijaa ja yli 4500 työntekijää, joista 400 on professoreita. Kampuksemme sijaitsee Espoon Otaniemessä. Monimuotoisuus on osa meitä, ja teemme jatkuvaa työtä yhteisömme monimuotoisuuden ja syrjimättömyyden varmistamiseksi. Siksi kannustammekin päteviä hakijoita taustasta riippumatta liittymään yhteisöömme.
Aalto-yliopiston Kemian tekniikan korkeakoulun Biotuotteiden ja biotekniikan laitos hakee
Entsyymiteknologian professoria
Tutustu laajempaan tehtävänkuvaukseen ja hakuohjeisiin yllä olevassa englanninkielisessä hakuilmoituksessa.Lisätietoja tehtävästä antaa professori Markus Linder (markus.linder@aalto.fi). Rekrytointiprosessiin liittyvissä kysymyksissä voit olla yhteydessä HR Partner Noora Katiskoon (noora.katisko@aalto.fi).
More about Aalto University:Aalto.fitwitter.com/aaltouniversityfacebook.com/aaltouniversityinstagram.com/aaltouniversity
The University of Eastern Finland is inviting applications for a Doctoral Researcher (Biomedical Informatics) position in Kuopio. The position will be filled for a two-year term from 1 November 2023 onwards (or as agreed). Please find more information below and submit your application by 4 September 2023.
Role and salary
As our new Doctoral Researcher in Biomedical Informatics, you will be working in the research group led by Associate Professor and Academy Research Fellow Vittorio Fortino in the Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, Kuopio Campus.
The Biomedical Informatics Group aims to develop machine learning-based applications to address biomedical research questions, including biomarker and drug discovery. We encourage applicants with expertise in R/Python programming, machine learning, network analysis, and fundamental knowledge in genomics and transcriptomics data analysis to apply.
The candidate will work on a project funded by Sigrid Jusélius Foundation. The position is part of a project aiming to identify new therapeutic options for specific groups of cancer patients by using omics data and drug repositioning approaches. We will analyse multi-omics data, such as genomics and transcriptomics, to identify potential biomarkers and drug targets for distinct patient groups based on their shared biological or clinical characteristics. Then, we will use drug repositioning methods to identify FDA-approved drugs that could be effective in treating these patients.
The successful candidate will have an MSc in Bioinformatics, Biosciences or some other discipline relevant to the Doctoral Researcher position (has completed a suitable higher university degree or an equivalent education abroad which in the country in question would qualify the person for similar academic studies).
The candidate shall also be qualified to pursue postgraduate studies at the University of Eastern Finland by enrolling in one of the doctoral programmes of the Faculty of Health Sciences.
We do not expect the candidate to have prior knowledge of machine learning and network data mining algorithms, as these will be learned in the position. However, the candidate should have a strong foundation in coding and be comfortable with the idea that the primary duties of this role will be coding and learning machine learning techniques.
The position will be filled for a two-year term from 1 June 2023 onwards (or as agreed) due to it pertaining to a specific project tasks. A probationary period is applied to all new members of the staff.
The salary of the position is determined in accordance with the salary system for the Finnish universities. The salary comprises two components: a job-related salary element and a personal salary element. For a Doctoral Researcher, the job-related salary element is €2,108.40–€2,628.85 /month, based on levels 2–4 of the job requirement level chart for teaching and research staff. The personal salary element is 6–50% of the above-mentioned sums.
At the beginning of the employment, the salary of the Doctoral Researcher will be €2,319–2,890 /month.
Requirements
Our requirements and expectations
qualifications to pursue postgraduate studies
excellent/good skills in oral and written English. English is used as the language of instruction and supervision in this position
a good computational (informatics/computer science/coding) background
solid knowledge of, and practical experience in, bioinformatics
experience of analysis of at least two different types of omics data (e.g., gene expression data, genomic data – GWAS, DNA methylation data, etc.)
programming experience in a relevant programming language (e.g., R and Python)
Expectations
previous research experience and ambitions will be taken into account during the evaluation process
ability to work independently and as part of a team
Advantages
an inquisitive mindset
a proactive attitude
the desire to further develop one’s skills in data science and machine learning
Your Benefits
You will have access to the university’s staff benefits, including
opportunity for flexible multi-location work
extensive occupational health care
broad selection of staff training
staff discount on lunch in our campus restaurants, as well as on a range of other services
affordable sports services and tax-free bike benefit
Please read more in the Work at UEF section on our website.
You will have an opportunity to work in an interesting, meaningful and diverse role as part of our international, creative, participatory and inclusive academic community.
Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.
How to apply?
Submit your application by using our electronic application form no later than 4 September 2023 by 24:00 (midnight) Finnish time (UTC+3).
Please note that you must include the following appendices in your application
copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas
motivation letter
the list of publications https://www.aka.fi/en/research-funding/apply-for-funding/how-to-apply-for-funding/az-index-of-application-guidelines2/list-of-publications/ (non mandatory)
recommendation letter(s) if available
other documents to demonstrate the applicant’s merits for the position
Questions?
For further information on the position, please contact Associate Professor Vittorio Fortino, +358 29 4454197, vittorio.fortino@uef.fi
For further information on the application procedure, please contact HR secretary Nea Itkonen, +358 29 4458373, nea.itkonen@uef.fi
The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 3 090 degree students and about 580 PhD students in the Faculty. The faculty has 800 staff members.
The University of Eastern Finland, UEF, is one of the most multidisciplinary universities in Finland. We have a staff of 3,200 members, and our academic community comprises around 16,000 degree students. Our campuses are located in Joensuu and in Kuopio. Our research is ranked among the best in the world in several fields. We generate research-based knowledge and make it openly accessible for the benefit of all. To learn more about our university please visit our website at www.uef.fi/en. On our website, you’ll also find information about the university as a work community and as an employer (https://www.uef.fi/en/article/one-university-a-thousand-stories), as well as our employees’ career stories (https://www.uef.fi/en/career-stories).
Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of approximately $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, growing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our global team of more than 100,000 colleagues delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. For more information, please visit www.thermofisher.com.
About Finland
Our Finland locations include Vantaa and Joensuu, employing over 800 professionals supporting functions such as production, instrument and reagent manufacturing, R&D, marketing, sales, quality, administrative support and supply chain. We hire experts in different fields including engineering, chemistry, microbiology and bioinformatics. Our Vantaa site develops pipettes and microplate instruments as well as clinical chemistry and industrial chemistry analyzers, laboratory automation solutions and food safety kits. It is conveniently located close to the Vantaankoski railway station. Please read more about Finnish sites, innovative work and collaborative colleagues at https://jobs.thermofisher.com/global/en/finland.Take a look how our software professionals in Finland are enjoying our innovative work atmosphere and the role they are playing in helping humankind: https://youtu.be/wDm4NLxq3nI
How will you make an impact?
We are looking for a proactive and self-driven Laboratory Technician for a permanent position in the Molecular Food Protection team. You enjoy working with high technology products and driving multiple initiatives at the same time. You want to develop yourself and the way of working. We offer motivating tasks in an innovative and international working environment.
What will you do?
You will be part of the Molecular Food Protection team, with up to 35 other members, responsible for designing and developing new molecular diagnostic products to complement the current microbiology product range, and production and support of these products.Your work will include conducting molecular experiment work on the enhancement of Molecular Food Protection manufacturing processes, quality and customer complaint investigations, and raw material and vendor qualifications. You will conduct molecular and microbial methods such as sample preparation, real-time PCR experiments, analyze results and maintain instruments and laboratory. You are expected to contribute by thinking through issues related to laboratory work. You are well-organized and able to maintain electronic laboratory notebooks.
How will you get here?
>1 years relevant experience of working in laboratory
Solid knowledge of real-time PCR and molecular methods
Knowledge of basic microbiological techniques and methods
Good computer skills and experience in MS Office package
Good written and spoken Finnish, and preferably English
Strong teamwork capabilities
Good communication and interpersonal skills
In addition to the interesting and versatile job, we offer:
Compensation on various methods from annual bonus scheme to colleague recognition program
Variety of occupational health care services and insurance
Epassi leisure benefit
Various hobby clubs with company sponsorship such as golf club, boating club, sport club etc.
Possibility to take part in our charity work
Career development and progression possibilities offered by our global network
Our comprehensive training platform and programs
Be part of our mission to enable our customers to make the world healthier, cleaner and safer
Please send in your application, including a cover letter, CV and salary request in English. Please apply via http://jobs.thermofisher.com/ by 3rd of September. Reference: R-01196962. Please apply as soon as possible, the position will be filled as soon as suitable candidate is found.If you have questions about Thermo Fisher Scientific and/or the position – please contact Pauliina Heikkinen, Supervisor, Manufacturing Sciences, tel. +358503581432 or pauliina.heikkinen@thermofisher.com.
About us:
Each one of our 100,000 extraordinary minds has a unique story to tell. It’s not just a career, it’s a chance to realize your best – professionally and personally.Join us and contribute to our mission—enabling our customers to make the world healthier, cleaner and safer: http://jobs.thermofisher.com
Orion’s Immuno-Oncology (IO) research team is looking to recruit an enthusiastic and motivated in vitro senior scientist to join the IO team in Turku, Finland, on permanent basis. In this role you will contribute to IO target identification and validation, coupled with being responsible for supporting IO drug discovery projects. In this role you have a unique opportunity to contribute in a range of treatment modalities ranging from small molecules, large molecules (bispecific & monospecific antibodies) and CAR T cells.
The responsibilities of this role include the following (including, but not limited to);
Design and perform in vitro immune assays and treatment with oncology drugs in conjunction with internal project teams.
Establish and validate human and mouse in vitro primary immune cells assays to define the mechanism of action of IO drugs.
Provide Immunology expert guidance and leadership to the project team as to the development of pharmacology strategy for IO drug discovery projects.
Provide expert knowledge of tumour biology and tumour immunology to the organisation.
Co-ordinate with the line-manager and project team to ensure timely delivery of data, and report if any issues encountered or foreseen.
Be responsible person for CRO and external partnered studies.
Develop and implement novel primary immune cells assay to improve the target confidence and in vitro pharmacology data package.
Provide clear reports and presentations as required and participate in project team meetings and organisation meetings.
Liaise with members from other organisation to establish potential biomarkers identification strategies.
Establish role as in vitro project lead within the organisation.
Working in close collaboration with other scientists and technicians.
Description Of Unit
Immuno-Oncology (IO) is one of the three Research teams in Orion’s Oncology R&D. IO team is accountable for novel drug discovery projects, identification of unmet need, identification & experimental validation of potential IO drug targets within state-of-the-art laboratories and technologies.
We Offer
We offer you the opportunity to show your talent in one of the most innovative companies in Finland. You get a chance to work in a challenging field of work with excellent colleagues. You will also have the chance to do meaningful work and build the future of Orion. We are striving for excellence in everything we do. We succeed, learn together and appreciate each other. You’ll be empowered to deliver value. Read more about our values!
Requirements
To be successful ideally you should have the following educational and professional work experiences:
PhD degree in Immunology, Immuno oncology or related field with 3+ years of Industry or academic experience.
Strong and deep knowledge in Immuno oncology, cancer immunotherapy, immune cell signalling as evidenced by high impact journal publication or poster presentation.
Previous experience working in pharma or biotech is a plus.
Strong in vitro research experience using primary immune cells assays is a must
Demonstrate ability to independently design, conduct and interpret the data from complex in vitro immune cell assays.
Demonstrate proficiency in isolation of immune cells and processing samples for multi-colour flow cytometry, multiplex ELISA, IHC, single cell RNA sequencing and gene expression analysis.
Competency in using graph pad prism, flowjo, nSolver software and other standard office software.
Excellent attention to details with strong communication skills.
Flexibility and willingness to learn new techniques and take additional responsibilities as a member of the research team.
Additional Information
Please send your application in English by 10 September 2023 at the latest.
For further information, please contact Dr Anil Thotakura, Head of Immuno-Oncology, +358 50 966 7229. Best time to contact: 23rd August Wednesday 15:30 to 16:30, 30th August Wednesday 15:30 to 16:30 and 6th September Wednesday 15:30 to 16:30.
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person. Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.
Are you interested in shaping the future of food by producing new sustainable food ingredients with cutting edge technology and with superb colleagues who are top experts in their field? Onego Bio might be just the place for you.
Onego Bio is a Finnish game-changing food-biotech company producing animal-free egg white with precision fermentation. The company’s award-winning technology has placed them at the forefront of the industry, having cracked the code to producing bioidentical egg proteins that provide the same taste, functionality and nutrition but without the poor efficiency and harmful impacts of animal agriculture. Onego Bio is launching its first product Bioalbumen® as an ingredient for the food industry and transforming the food system to meet the urgent sustainability requirements of the world. The company is focused on scaling precision fermentation to industrial scale with the superior Trichoderma reesei production platform.
Founded by alternative protein pioneer Maija Itkonen (CEO) and precision fermentation trailblazer Christopher Landowski (CTO), Onego Bio is a spin-off that salutes the remarkable work done by VTT Technical Research Centre of Finland for the next level cellular agriculture products and applications. Since launching, the company has received massive international recognition, including being selected as a winner of Fast Company’s 2023 World Changing Ideas Awards. Onego Bio is a founding member of Food Fermentation Europe and Precision Fermentation Alliance US. Get to know us better by exploring our webpage www.onego.bio
We are now looking for a scientist / senior scientist to join our R&D team.
In this position, you will play an essential role in developing, planning, and carrying out research projects with a project team and contribute towards our greater goal of providing nature-identical egg protein ingredients to the world at scale. Ultimately, we aim to be part of building a sustainable food system with the help of our partners throughout the world. Towards this goal our R&D team is creating microbial production systems for expressing egg white proteins using filamentous fungi.
Your primary responsibilities will be:
Scientific project work in the fields of protein production and molecular biology
Combining your expertise in molecular biology and protein engineering together with food science to ensure our product meets all the needs of the food industry, our customers and the consumers
Developing protein screening technologies and workflows.
Further developing our expression platforms using the newest innovations
Who we are looking for:
Proven, excellent laboratory skills and experience in molecular biology techniques such as DNA cloning, gene engineering, protein analysis, protein purification and characterisation.
Completed PhD in biotechnology, molecular biology, protein chemistry, or a related field.
Four or more years of experience working with recombinant proteins
Good written and spoken English skills
Proven ability to effectively execute and manage scientific activities: both on the bench and beyond
Someone with deep knowledge in the fields of protein biology and assay development
Industrial experience working in a biotechnology company would be a big plus
As a person, we hope that you:
Love science and innovation
Consider yourself a protein expert
Skilfully and precisely plan and perform experiments with desired goals
Self-motivated and willing to take the initiative to get projects accomplished
Have strong communication and collaboration skills
Work well with other team members and contribute to a good working environment
Can tolerate pressure and maintain a good work-life balance
Are flexible to take on a variety of tasks anticipated in a start-up company
What we offer you:
Molecular biology with an impact. Onego Bio is transforming the future of egg production by creating cutting-edge microbial protein production systems. Microbial production technology to produce egg white protein can significantly mitigate environmental impacts according to the LCA study published in Nature Food. The positive impact of our technology does not only contribute positively on the environment but also supply chain stability, global health, food security and animal welfare. Egg is one of the world’s most popular proteins and our team stands to meet the demand in a way that preserves the future of our planet.
Superb colleagues. We offer working in a passionate environment within a fun and diverse team who want to make an impact in the world. With Onego Bio, you will join a dedicated group of top experts in their respective fields who foster a culture of trust, openness, and sharing ideas.
Competitive salary. We want to attract the best people, so we will provide competitive salaries.
Nordic work–life balance. Working in Finland, the happiest country in the world, enables a high quality of life. At Onego Bio, we make our people’s well-being a priority. We offer 6 weeks paid vacation a year, among other benefits including extended occupational healthcare, and exercise and culture benefits.
Employment type: Full-time, Permanent
Location: Helsinki, Finland
Apply now and join our community of brilliant minds!
Please send your CV and application letter as a combined file as soon as possible but at the latest by 27 Aug 2023. We will process applications as they come in and fill the position as soon as we find the right candidate.
Interested and want to hear more?
For further information, please contact Arnab Bhattacharjee, Head, Discovery research at arnab.bhattacharjee@onego.bio
