28.8.2017 | Ajankohtaista
We are looking for a post-doctoral researcher to join our team at Unit of Metabolism, Minerva Foundation Institute for Medical Research.
Unit of Metabolism is lead by docent Heikki Koistinen. The main interest of the group is to understand the molecular mechanisms regulating insulin sensitivity in human skeletal muscle, using primary human muscle cells as a research model.
We are looking for a post-doctoral researcher who is experienced in cell culture, analyses of intracellular signaling as well as metabolic studies in vitro.
The preferred starting date is November 2017. The deadline for applications is September 20th, 2017 or until suitable candidate is found.
If you are interested in joining the lab please send your application by e-mail (heikki.koistinen@helsinki.fi) as a single pdf that includes:
– a cover letter describing your motivation, as well as your research accomplishments
– current CV and list of publications
– contact information of three references (e.g. MSc/PhD thesis supervisors).
Heikki Koistinen, docent, MD, DMSci, head of group
Unit of Metabolism
Minerva Foundation Institute for Medical Research
Biomedicum 2U Helsinki
Tukholmankatu 8
00290 Helsinki, Finland
28.8.2017 | Ajankohtaista
A postdoctoral fellow OR graduate student position in the field of RNA Polymerase II Gene Regulation is open in Barboric laboratory, Faculty of Medicine, University of Helsinki. The deadline for this application is October 1, 2017 or until the position is filled.
The Barboric Lab is committed to elucidating fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in essential cyclin-dependent kinases which trigger Pol II release from promoter-proximal pausing and facilitate productive Pol II elongation along genes. We employ biochemistry, genetics and genome wide approaches to understand how Pol II pause release is controlled by the positive transcription elongation factor (P-TEFb) and its inhibitory 7SK snRNP complex. Moreover, we are examining how another critical transcription elongation kinase, the Cdk12/CycK complex, impacts target gene expression, and how frequent CDK12 mutations in ovarian carcinoma perturb gene expression to enable genesis of this deadly disease. Finally, we are aiming to define novel mechanisms that promote integration of Pol II transcription with maturation of precursor RNA transcripts. Salary of the successful candidate will be provided by the 4-year grant entitled ‘Significance of transcription elongation kinases in DNA damage response’, which was funded recently by The Academy of Finland.
Requirements
I am looking for a creative and independent thinker with a strong passion for science and the ability to excel in a competitive field of gene transcription. The competitive candidate should hold MSc or PhD degree in molecular biology, biochemistry, bioinformatics or related fields. Wide expertise in biochemistry and molecular biology is a pre-requisite for the position. In addition, expertise in the analysis of next generation sequencing data is appreciated. Excellent publication record as well as good command in spoken and written English is required. Please send your application including a cover letter, CV, summary of your research interests, and 2-3 letters of reference to [matjaz.barboric@helsinki.fi]matjaz.barboric@helsinki.fi.
Employment conditions
Selected candidate will be offered employment contract in accordance to the University of Helsinki salary scale system with the initial 4-month trial period.
Faculty of Medicine offers a unique and stimulating research environment surrounded by state-of-the-art resources and facilities of the leading and largest biomedical research campus in Finland.http://www.biomed.helsinki.fi/english/
The University of Helsinki is a research oriented university which offers stimulating and international environment and ranks amongst top 15 best universities in Europe, www.helsinki.fi/en
The University of Helsinki rents apartments with quite reasonable rents to the international post-docs. Employees of the University of Helsinki are covered by excellent health insurance that is free of charge, www.helsinki.fi/intstaff/
For further information, please contact:
Matjaz Barboric, Ph.D.
Principal Investigator
Faculty of Medicine, University of Helsinki
Biomedicum Helsinki 1, Room B131b
Haartmaninkatu 8, 00290 Helsinki, Finland
Email: [matjaz.barboric@helsinki.fi]matjaz.barboric@helsinki.fi
21.8.2017 | Ajankohtaista
A doctoral candidate position offered to study the molecular mechanism of RNA polymerase I at the Department of Biochemistry, University of Turku. Apply by 30.9.2017.
More information at:
21.8.2017 | Ajankohtaista
Exciting PhD positions at the European Molecular Biology Laboratory (EMBL)
Job Description
The European Molecular Biology Laboratory (EMBL) invites you to apply for PhD positions in Heidelberg, Barcelona, Grenoble Hamburg, Hinxton (near Cambridge) and Rome. Would you like tocontribute your creativity to an international team of scientists from all disciplines focusing on basic research in the area of molecular life sciences?
We invite candidates with background in Biology, Chemistry, Physics, Mathematics, Computer Science, Engineering and Molecular Medicine to apply.
EMBL opens the door to your scientific career: our students have an outstanding publication record, are a vital part of our global collaborations and receive their degrees jointly with our network of excellent partner universities in 17 different countries.
Our PhD positions come with generous fellowships, including broad health care benefits and pension access.
Application Instructions
The registration deadline is 16 October 2017.
The deadline for submission of the online application is 23 October 2017.
Interviews will take place beginning of February 2018 in Heidelberg and a week prior in the Outstations.
Additional Information
EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation. Successful candidates would start their work at EMBL latest by mid of October 2018.
21.8.2017 | Ajankohtaista
Applications are invited for a postdoctoral research associate position in the laboratory of Dr. Walid Khaled.
The successful candidate will work on a project funded by Breast Cancer Now aimed at the identification and characterization of novel protein-protein interactions in triple negative breast cancer.
Applicants should have, or expect to obtain shortly, a PhD in the life sciences and have demonstrable experience in studying protein-protein interactions and/or a strong interest in cancer biology. The candidates will need to have strong experience in the following techniques: cell culture, molecular biology (cloning), proteomics, biochemical assays or biophysical assays. It will also be desirable if the candidate has experience in working with GEMM and NGS data analysis.
You must be a careful and methodical worker, accurate and ready to take responsibility as part of a team. You should be self-motivated and able to organise, perform and analyse experiments with minimal instruction. You will have several years of previous laboratory experience and be capable of working efficiently and productively without direct supervision. The post will require some weekend work. Careful observation and accurate computer-based record keeping and presentation are essential.
The successful candidate will join the Epithelial Tumour Biology group led by Dr Khaled, studying various aspects of triple negative breast cancer and squamous lung carcinoma. With a wide range of expertise, team members regularly collaborate amongst themselves and with scientists from other Cambridge Institutes. The successful candidate is expected to interact and work closely with other members of the team.
The Department holds an Athena SWAN bronze award, demonstrating a commitment to provide equal opportunities and to advance the representation of women in science subjects. We welcome applications from all qualified candidates irrespective of gender but, as women are currently underrepresented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone.
For the online application, you will need to provide your personal details, names and e-mail addresses of two referees familiar with your recent research, CV, publications and a cover letter (including a description of your experience as it relates to the job specifications). For enquiries about the online application process please contact Ms Saez (
pharsect@hermes.cam.ac.uk). Applications from agencies will not be considered.
The closing date is 30th September 2017. Interviews will be carried out as applications are received.
Informal enquiries should be made to Dr. Walid Khaled (
wtk22@cam.ac.uk).
The position is available for 2 years (subject to a probation period) in the first instance and is available from 1st October 2017 or soon thereafter. There is a possibility of a third year subject to excellent performance.
The Department of Psychiatry at Indiana University School of Medicine, in conjunction with the Stark Neurosciences Research Institute, is seeking to fill an immediate opening for a full-time tenure track position at the level of Associate Professor or Professor.
Candidates should possess a doctoral degree in psychology, psychiatry, neuroscience, or a related field and have established research credentials in the area of neural mechanisms underlying alcohol and/or drug addiction, including nicotine, cannabinoids, opiates or psychostimulants. Responsibilities will include: developing and sustaining an independent research program that will complement present on-going basic and translational research activities, and providing a foundation for better integration of research activities among current investigators, with the overall goal of enhancing our understanding of neurobehavioral and genetic mechanisms underlying alcohol and drug abuse and translating these findings to benefit patients.
Research space will be in the new Neurosciences Building; investigators in this building have access to state-of-the-art Core Facilities. Other responsibilities will include participation on department committees and teaching of residents, interns, medical students and graduate students. The department and the university place a high priority on creating a diverse learning environment and on supporting the professional development of ethnic minorities, women, and people with disabilities. Applications are encouraged from professionals of all ethnic backgrounds.
Located in Indianapolis, Indiana University School of Medicine is the second largest medical school in the United States, with a student body that includes over 46% women and 7% ethnic minorities. Indianapolis is the 13th largest city in the United States and is a growing, diverse city with a rich cultural heritage. In addition to having active sports, cultural, arts and educational events and programs, Indianapolis is located centrally near several other major cities, including Chicago, Louisville, Cincinnati and Columbus.
Interested applicants should send their curriculum vitae and statement of research experience and interests to majhughe@iupui.edu (Attn: William J. McBride, Ph.D.,).
Applications will be accepted until this position is filled. The departmental website is located at http://www.iupui.edu/~psych/ . Indiana University School of Medicine is an Equal Opportunity Employer/Affirmative Action, M/F/D.
21.8.2017 | Ajankohtaista
Two postdoctoral fellow positions are available at Mount Sinai School of Medicine, Department of Neuroscience, in New York.
1) Studies of epigenetic mechanisms of chronic pain.
The project involves the use of advanced transgenic mouse models, biochemical and genomic methods, for the study of brain region-specific adaptations associated with nociceptive sensitization and/or chronic pain induced mood disorders. Applicants must have a PhD degree in the Neuroscience or Molecular Biology. Experience in molecular biology/biochemistry is highly preferred. Other desired skills include experience in mouse behavior, small animal surgery or electrophysiology.
2) Studies on addiction vulnerability under chronic pain states.
The project involves the use of transgenic mouse models, live imaging and brain biochemistry to understand the mechanisms underlying the actions of opioids under chronic pain states. Experience in small animal surgery and mouse behavior is highly preferred.
Interested Individuals should send a short letter of interest, a CV and include contact information for at least 3 references to: venetia.zachariou@mssm.edu
14.8.2017 | Ajankohtaista
The Institute for Molecular Medicine Finland (FIMM) is an international research institute focusing on human genomics and personalised medicine at the University of Helsinki. In the beginning of 2017 FIMM joined the University of Helsinki’s new life science research centre, Helsinki Institute of Life Science HiLIFE, as an operational unit. FIMM integrates molecular medicine research, technology centre and biobanking infrastructures under one roof, promoting translational research in grand challenge projects, specifically, the impact of genome information from the Finnish population in personalised health and medicine, individualised cancer medicine, and digital molecular medicine. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.
FIMM is currently seeking Research Coordinator for High Throughput Screening Operations
Description:
The High Throughput Biomedicine (HTB) unit of the FIMM Technology Centre performs high throughput bioassays, mainly cell-based drug screening and RNAi experiments. The unit supports research at University of Helsinki and functions as a national and international infrastructure platform mainly for academic researchers. We currently have an opening for a Post-doc/Research Coordinator for project management and coordination. The primary activities of the position include, but are not limited to:
– Project management and coordination
– Method and protocol development (especially in 3D tumor models)
– High throughput screening
– Administration of the HTB unit
The research coordinator will work independently as well as closely with HTB researchers and staff. The specific tasks include management of academic/company collaborations, in vitro disease modeling, microscopy, administration of unit finances and academic writing of applications and reports, high throughput screening, protocol development and data management.
Qualification and experience:
Candidates should have PhD degree in biotechnology, biology, biochemistry, engineering, or a related discipline including proven experience with at least: project management and coordination, supervision of personnel, drug sensitivity testing, handling of clinical samples, cell culture, biochemical, molecular, or cellular techniques, assay development, high content microscopy, flow cytometry, laboratory automation, robotics, and high-throughput screening. The successful candidate is expected to have excellent problem solving, organisational, and analytical skills, and is able to work systematically. In addition, the candidate should be fluent in English, have good interpersonal and communication skills, a service-minded attitude, and be able to work independently as well as within a team.
9.8.2017 | Ajankohtaista
https://www.helsinki.fi/fi/avoimet-tyopaikat/tutkimusteknikko-biotieteiden-laitokselle
Helsingin yliopiston Bio- ja ympäristötieteellisen tiedekunnan (www.helsinki.fi/bio) biotieteiden laitos hakee
TUTKIMUSTEKNIKKOA
määräaikaiseen työsuhteeseen 21.8.2017-31.7.2019.
Tutkimusteknikko toimii Viikin kampuksella yleisen mikrobiologian osastolla opetuksen ja tutkimuksen elatusaineiden ja liuosten vastuuhenkilönä sekä maljanvalulaitteen ja opetuslaitteiden vastuuhenkilönä. Tutkimusteknikko kuuluu tiimiin, joka tarjoaa teknistä tukea biotieteiden laitoksen yleisen mikrobiologian opetukselle ja tutkimukselle.
Tutkimusteknikon tehtäviin kuuluu elatusaineiden ja liuosten valmistamista, aseptista työskentelyä, mikrobiologista ja molekyylibiologista työskentelyä, mikrobiologisen ja molekyylibiologisen laboratorion peruslaitteiden ja -välineiden käyttöä. Tutkimusteknikko huolehtii kurssisalien siisteydestä ja varustelusta yhteistyössä muiden osastolla toimivien henkilöiden kanssa ja osallistuu yleisiin osastotason tehtäviin. Hän sijaistaa tarvittaessa yleisen mikrobiologian välinehuollossa ja autoklaavien käytössä. Tutkimusteknikon tehtäviin sisältyy ajoittain osaston tutkimusryhmissä avustamista.
Tutkimusteknikko toimii vaihtelevissa tehtävissä yksilöllisesti, tiimissä sekä tutkimusryhmissä. Tehtävät vaativat hyvää organisointikykyä ja paineensietokykyä. Valittavalla henkilöllä tulee olla kyky toimia tarkkuutta vaativissa mikrobiologisissa ja molekyylibiologisissa tehtävissä.
Tehtävässä vaaditaan kykyä itsenäiseen työskentelyyn, mutta myös osallistumista tiimityöskentelyyn sekä vuorovaikutusta suomalaisten ja kansainvälisten opiskelijoiden sekä tutkijoiden kanssa suomeksi ja englanniksi.
Tehtävän menestykselliseen hoitamiseen vaaditaan riittävän hyvää englannin ja suomen kielen taitoa, tietoteknisiä perusvalmiuksia, kiinnostusta uusien menetelmien oppimiseen sekä halua kehittyä työssään ja kokemusta laboratorion laatujärjestelmistä.
Tehtävän palkkaus perustuu yliopistojen palkkausjärjestelmän muun kuin opetus- ja tutkimushenkilöstön vaativuuskehikon tasoon 6. Lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuva palkanosa. Palkka työsuhteen alkaessa on noin 2100-2400 euroa valittavan henkilön osaamisen ja kokemuksen mukaan. Tehtäviin palkataan neljän kuukauden koeajalla.
Hakemus jätetään yliopiston sähköisen rekrytointijärjestelmän kautta Hae paikkaa –linkistä. Yliopistoon työsuhteessa olevat sisäiset hakijat jättävät hakemuksensa tehtävään SAP HR –portaalissa. Liitä hakemukseen mukaan yhtenä pdf-tiedostona (mieluiten englanniksi):
– ansioluettelo (sisältäen kahden suosittelijan sähköpostiosoitteet ja puhelinnumerot, joista suosittelijat tavoitetaan päiväsaikaan)
– motivaatiokirje (max 1 sivu).
Hakuaika päättyy 16.8.2017 ja haastattelut järjestetään 18.8.2017.
Lisätietoja tehtävästä antavat professori Sarah Butcher ja Viikin laboratoriohenkilöstön poolin koordinaattori Minttu Ahjos (etunimi.sukunimi(at)helsinki.fi).
Rekrytointijärjestelmän tekninen tuki: rekrytointi(at)helsinki.fi
Hae viimeistään 16.08.2017
HAE PAIKKAA
https://rekry.helsinki.fi/sap/bc/erecruiting/posting_apply?param=cG9zdF9pbnN0X2d…
HAKU PÄÄTTYY
keskiviikko, elokuu 16, 2017
8.8.2017 | Ajankohtaista
Although there are other ways of becoming a postdoc at our institute, the DKFZ Postdoctoral Fellowships represent the most prestigious and competitive Postdoc recruitment process at DKFZ. It is intended to recruit highly talented and motivated young scientist, who wish to work at the forefront of cancer research in any of basic or translational cancer research labs at the DKFZ.
This program offers up to 10 fellowships per year and provides interdisciplinary training and research opportunities in state-of-the-art research facilities for excellent young scientists, no longer than 2 years past graduation, with a background in biology as well as in physics, mathematics, bioinformatics and other fields.
Deadline for applications is September 15, 2017.