Ajankohtaista

Asiantuntija lääkinnällisten laitteiden (IVDR) ilmoitettuun laitokseen

5.8.2025 | Avoimet työpaikat

Apply latest 26.8.

https://duunitori.fi/tyopaikat/tyo/eurofins-electric-electronics-finland-asiantuntija-laakinnallisten-laitteiden-ivdr-ilmoitettuun-laitokseen-sdsuu-19478714?utm_source=loimu&utm_medium=site

Työpaikkakuvaus

Yrityksen kuvaus

Eurofins Electric & Electronics Finland Oy on osa kansainvälistä Eurofins Groupia. Tarjoamme kattavia asiantuntija-, sertifiointi-, testaus- ja tarkastuspalveluja. Meillä työskentelee noin 50 eri alojen asiantuntijaa. Suomessa toimipisteemme ovat Espoossa, Salossa, Tampereella ja Oulussa. 

Lue lisää meistä: https://www.eurofins.fi/electrical-and-electronics/

Toimimme Fimean nimeämänä ilmoitettuna laitoksena EU:n lääkinnällisiä laitteita koskevien asetusten (MDR ja IVDR) puitteissa. Nyt haemme asiantuntijoita Medical Devices -tiimiimme. Toimipaikka on Tampere, mutta työ onnistuu myös muissa toimipisteissämme.

Tehtävän kuvaus

Haemme nyt asiantuntijaa, jolla on kokemusta in vitro -diagnostiikkaan tarkoitetuista lääkinnällisistä laitteista, ja joka haluaa kehittyä vaativaan asiantuntijatehtävään. Erityiseksi eduksi katsomme, jos hakijalla on valmiudet toimia sisäisenä kliinikkona.

Asiantuntijan pääasiallinen tehtävä on lääkinnällisten laitteiden ja valmistajien laadunhallintajärjestelmien auditointi sekä tuotteiden vaatimustenmukaisuuden arviointi CE-merkintää ja markkinoille saattamista varten.Odotamme sinulta

  • Työkokemusta IVD-laitteiden parista (esim. laboratoriotyö, tuotekehitys, kliiniset suorituskykyarvioinnit, validoinnit, laadunhallinta tai viranomaisvaatimukset)
  • Soveltuvaa korkeakoulututkintoa (esim. biokemia, mikrobiologia, virologia, patologia, genetiikka)
  • Sisäisen kliinikon tehtävään soveltuva koulutus on esim. sairaalakemistin, -mikrobiologin, -geneetikon pätevyys tai kliinisen alan erikoislääkäritutkinto
  • Kokemusta laadunhallintajärjestelmistä (esim. ISO 13485) ja IVDR:n vaatimuksista
  • Kykyä itsenäiseen työskentelyyn ja tekniseen arviointiin
  • Hyvää suomen ja englannin kielen taitoa
  • Valmiutta matkustaa (n. 30 päivää vuodessa)

Mikäli tehtävään valitaan sisäinen kliinikko, hänen vastuulleen kuuluu lisäksi:

  • Kliinisten suorituskyvyn arviointien kliininen tarkastelu ja ohjaus
  • Ulkopuolisten kliinisten asiantuntijoiden koulutus ja koordinointi
  • Arviointien vertailukelpoisuuden ja johdonmukaisuuden varmistaminen
  • Suositusten laatiminen päätöksenteon tueksi

Tarjoamme sinulle

  • Merkityksellisen työn lääkinnällisten laitteiden turvallisuuden ja vaatimustenmukaisuuden parissa
  • Mahdollisuuden kehittyä asiantuntijana kansainvälisessä toimintaympäristössä
  • Joustavat työskentelymahdollisuudet ja asiantuntevan tiimin tuen
  • Kilpailukykyiset henkilöstöedut ja koulutusmahdollisuudet
    Kiinnostuitko? Lähetä hakemuksesi ja CV:si osoitteeseen viimeistään 26.8.2025. Lisätietoja tehtävästä antaa Business Unit Manager Sanna Jakonen (040-8402567) 5.8.2025 klo 12-14 tai HR Specialist Synne Nordström (040-8469697).

Postdoctoral Researcher, Genomics, Bioinformatics, Faculty of Science

5.8.2025 | Avoimet työpaikat

https://oulunyliopisto.varbi.com/fi/what:job/jobID:846393

Apply latest by 21.08.2025

Faculty of Science, Ecology and Genetics 

The University of Oulu is a multidisciplinary, international research university, with about 4000 employees who produce new knowledge based on high-standards research and provide research based education to build a more sustainable, smarter, and more humane world. The University of Oulu community has about 17,000 people in total. Our northern scientific community operates globally and creates conditions for the emergence of innovations.  

We are now looking for

A Postdoctoral researcher

who will focus on bioinformatic analyses of genomic data obtained from archaeological finds of domesticated animals. 

About the job

You will be working with and supported by a group of enthusiastic researchers in a multidisciplinary project that combines historical, archaeological and genetic methods to study the early history of poultry and horses in Northeastern Europe. This project is also a part of the research of the Wildlife Genomics Research group (https://wildlifegenomics.wordpress.com/). Specifically, you will produce and analyze genomic data obtained from archaeological finds of poultry and horses from the region around the Baltic Sea.

Who are you?

We expect that you have:

  • A PhD in biology (or a relevant field) obtained no more than ten years ago, and prior experience in bioinformatic analyses of genomic data, and knowledge of population genomics
  • Demonstrated effective writing skills through high-quality publications, including some international experience and networking
  • Demonstrated capability to work independently and in collaboration with colleagues.
  • Fluent in English, both in oral and written communication.

What we offer?

  • Collaboration with and support from a group of enthusiastic researchers in a multidisciplinary project that combines historical, archaeological and genetic methods to study the early history of poultry and horses in Finland, but still independent work.
  • You will have the opportunity to develop professionally with the assistance of the experienced research group, including participation in local, national, regional and international meetings and workshops.
  • This is an in-person position, with the possibility of flexible working hours via well-established practices and agreements and local teleworking.
  • Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits. 
  • Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us. 
  • Our Buddy Program and Spouse Network support you and close ones in settling into Oulu.
  • We have an HR Excellence in Research -quality label, which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
  • Finland is one of the most livable countries in the world, with a high quality of life, safety, an excellent education system, and a competitive economy. Read more about living in Oulu.

Appointment and salary

The position is fixed-term for 4 years as of 1.9.2025 or as soon as possible thereafter, ending 31.8.2029. The salary will be based on levels 5-6 of the demand level chart for Finnish universities’ university-level teaching and research staff. In addition, a salary component based on personal work performance will be paid (a maximum of 50% of the job-specific component). The starting gross salary will be approximately 3800-4200 € per month, depending on the qualifications. A trial period of 6 months is applied to the position.

How to apply

 The applications are submitted through the Oulu University recruitment system online, the latest by 21st August 2025 (https://oulunyliopisto.varbi.com/en/). In the application, the applicant should attach:

  • Curriculum vitae
  • Publication list
  • A short cover letter describing motivation and previous experience in relation to the competences mentioned above
  • Copies of certificates or diplomas
  • Contact information of two persons available for recommendations

The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview.

Contact information

If you have any further questions, please contact Docent Laura Kvist (laura.kvist@oulu.fi)

Type of employmentTemporary position over 6 months
Contract typeFull time
First day of employment1.9.2025
Number of positions1
Full-time equivalent100%
CityOulu
CountyPohjois-Pohjanmaa
CountryFinland
Reference number2025/446
ContactLaura Irmeli Kvist
Published04.Aug.2025 
Last application date21.Aug.2025

Protein Scientist / Research and Development – Onego Bio, Helsinki

31.10.2024 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/4061099870/?refId=5c0b0874-a9e2-4277-a0e9-660d0ef4f912&trackingId=%2FHp21%2BXGQ2Oo1HL1Emqoiw%3D%3D

About the job

Are you interested in shaping the future of food by producing new sustainable food ingredients with cutting edge technology and with superb colleagues who are top experts in their field? Onego Bio might be just the place for you.

Onego Bio is a Finnish leading food-biotech company producing animal-free egg protein with precision fermentation. The company’s award-winning technology has placed them at the forefront of the industry, having cracked the code to producing bioidentical egg proteins that provide the same taste, functionality, and nutrition but without the poor efficiency and harmful impacts of animal agriculture. Onego Bio is launching its first product Bioalbumen® as an ingredient for the food industry and transforming the food system to meet the urgent sustainability requirements of the world. The company is focused on scaling precision fermentation to industrial scale with the superior Trichoderma reesei production platform.

Founded by alternative protein pioneer Maija Itkonen (CEO) and precision fermentation trailblazer Christopher Landowski (CTO), Onego Bio is a spin-off that salutes the remarkable work done by VTT Technical Research Centre of Finland for the next level cellular agriculture products and applications. In April 2024 Onego raised a $40M Series A funding round (one of the largest in the Nordics) for fueling scale up and go-to-market in the US. Similarly, in July 2024 Onego secured €14M / $15.2M new funding from the European Innovation Council (EIC) Accelerator Program and additional Series A investors. In 2024 Onego Bio has successfully raised altogether €50.5M / $55M, bringing the company’s total funding to € 65M / $70.8M. Since launching, the company has received massive international recognition, including being selected as a winner of Fast Company’s 2023 World Changing Ideas Awards. Onego Bio is a founding member of Food Fermentation Europe and Precision Fermentation Alliance US. Get to know us better by exploring our webpage www.onego.bio/about-us

We are now looking for an experienced Protein Scientist to join our R&D team in Helsinki, Finland

In this position, you will play an essential role in supporting and leading development projects within R&D and contribute towards our greater goal of providing animal-free egg protein ingredients to the world. We aim to play a significant role in building the sustainable food system with the help of our partners throughout the world. Towards this goal our team utilizes microbial production systems for expressing egg white proteins using filamentous fungi.

Your responsibilities as Protein Scientist:

  • Conducting scientific projects in the fields of molecular biology and protein production.
  • Using your expertise in molecular biology and protein engineering to address challenges in egg white protein production.
  • Developing protein screening technologies and workflows for novel egg white protein production.
  • Further developing our protein expression platforms with the newest innovations.
  • Comprehensive and timely documentation of activities in electronic lab notebooks and relevant databases.

Who we are looking for:

  • Candidate should have a Master’s degree in biotechnology, molecular biology, protein chemistry, or related field.
  • Proven, excellent laboratory skills and experience in molecular biology and protein science techniques, including DNA cloning and mutagenesis, protein expression, protein purification using chromatography techniques, protein analysis, assay development, and protein functional characterization.
  • Preference will be given to candidates with experience working in yeast or filamentous fungi.
  • Industrial experience working in a biotechnology company would be a big plus.
  • Good scientific reporting skills.
  • Good written and spoken English skills.
  • Proven ability to effectively execute and manage scientific activities: both on the bench and beyond.

As a person, we hope that you:

  • Independently plan your work and execute experiments skillfully and precisely.
  • Are self-motivated and willing to take the initiative to get things accomplished.
  • Eagerly want to continuously develop methods and ways of working.
  • Have effective communication skills.
  • Work well with other team members and contribute to a good working environment.
  • Can tolerate pressure and maintain a good work-life balance.
  • Are flexible to take on a variety of tasks anticipated in a start-up company.

With Onego Bio, you’ll enjoy:

  • Molecular biology with an impact. Onego Bio works on creating cutting-edge microbial protein production systems. Microbial production technology to produce egg white protein shows potential to significantly mitigate environmental impacts up to 90% according to recent study published in Nature Food. The positive impact of our technology does not only contribute positively on the environment but also supply chain stability, global health, food security and animal welfare. Egg is one of the world’s most popular proteins and our team stands to meet the demand in a way that preserves the future of our planet.
  • Superb colleagues. We offer working in a passionate environment within a fun and diverse team who want to make an impact in the world. With Onego Bio, you will join a dedicated group of top experts in their respective fields who foster a culture of trust, openness, and sharing ideas.
  • Competitive salary. We want to attract the best people, so we will provide competitive salaries.
  • Nordic work–life balance. Working in Finland, the happiest country in the world, enables a high quality of life. At Onego Bio, we make our people’s well-being a priority. We offer 6 weeks paid vacation a year, among other benefits including extended occupational healthcare, and exercise and culture benefits.
  • Employment type: Full-time, Permanent
  • Location: Helsinki Finland (on site)

Apply now and join our community of brilliant minds!

Please send your CV, application letter and salary request as a combined file as soon as possible but at the latest by 30th November 2024. We will process applications as they come in and fill the position as soon as we find the right candidate.

Interested and want to hear more?

For further information, please contact: Senior Scientist, Dr. Sudeep Karki, email: sudeep.karki@onego.bio

Read more about our past work on the topic:

https://www.hs.fi/visio/art-2000010306262.html

https://www.greenqueen.com.hk/onego-bio-series-a-funding-precision-fermentation-egg-protein-gras

https://www.fastcompany.com/90878786/onego-bio-bioalbumen-animal-free-egg-whites

https://foodmatterslive.com/article/precision-fermentation

https://www.talouselama.fi/uutiset/ovatko-tassa-suomen-seuraavat-kasvuraketit-talouselaman-lista-paljastaa-10-kiinnostavinta-startupia/2dcba57f-b63d-41f4-82d8-0e9689c57e5b

https://sifted.eu/articles/foodtech-startups-to-watch

https://www.onego.bio/press/our-news/seed-round

https://www.onego.bio/press/our-news/additional-funding

https://www.onego.bio/press/our-news/perfectday-nth-bio

We look forward to hearing from you!

Regulatory Affairs Officer, Animal Health – Orion Corporation, Turku

31.10.2024 | Avoimet työpaikat

https://duunitori.fi/tyopaikat/tyo/orion-regulatory-affairs-officer-animal-health-orion-corporation-turku-turku-sdsuu-18711291?utm_source=loimu&utm_medium=site

Job description

Orion Animal Health is seeking to hire a Regulatory Affairs Officer to join our team of regulatory professionals!

Description of Position 

The purpose of this role is to contribute to the management and support of regulatory activities for veterinary medicinal products, ensuring they meet global standards. As a Regulatory Affairs Officer you will have the opportunity to develop expertise in regulatory procedures, particularly for new marketing authorisation applications in the EU and US. You’ll also gain a deeper understanding of regulatory guidelines and processes while collaborating with internal teams, and global partners. Additionally, the position involves ensuring compliance with Good Manufacturing Practices (GMP) and regulatory procedures, playing a key part in supporting the company’s broader regulatory strategy.

As a Regulatory Affairs Officer, you will play a key role in the entire lifecycle of veterinary medicinal products – from the development of new medicinal products to initial global marketing authorisation applications, market launches as well as maintaining current authorisations.

You will collaborate closely with the Orion Animal Health regulatory team located in Finland, Belgium and France, as well as with other organisations and stakeholders internally and externally.

Your main responsibilities as a Regulatory Affairs Officer will include:

  • preparing administrative documentation for global regulatory submissions (e.g. Clinical Trial Authorisations, Marketing Authorisation Applications, variations) in EU, USA and elsewere
  • engaging with Competent Health Authorities before and during regulatory proceedings
  • preparing and updating product information materials (Summary of Product Characteristics, label, package leaflet)
  • serving as a regulatory affairs expert in cross-functional teams and/or in projects
  • documenting outcome of regulatory procedures in our IT-systems and request change controls
  • review and approval of artwork
  • coordinate regulatory procedures internally, with service providers and global partners
  • follow GxP practices, regulatory procedures, and processes

You have the opportunity to develop yourself as a regulatory affairs expert and to contribute to global regulatory strategies. This is a permanent position based in Turku, Finland.

Description of Unit

This position is located in the Regulatory Affairs & Pharmaceutical Development team, which belongs to the Animal Health R&D organisation within the Orion Animal Health Business Unit. In this dynamic cross-functional team we have experts from different areas of expertise working across different countries: Finland, France and Belgium.

Orion Corporation’s business division Animal Health (AH) comprises more than 350 employees in 11 countries. We produce and distribute over 300 veterinary medicines and are present in over 100 markets around the world servicing the needs of our customers in both the companion animal and livestock sectors. Our manufacturing and supply chain operations are located in Finland, France and Belgium.

Orion Corporation is a pharmaceutical company listed on the Helsinki, Finland stock exchange. Read more about Orion as an employer from the website https://www.orion.fi/en/careers/orion-as-an-employer/

We Offer 

We offer you versatile, interesting and challenging responsibilities in a multi-professional and international environment. You will be part of a great team with skilled and highly motivated colleagues. Appreciation of colleagues and continuous development are part of our core values. You will have the chance to grow your skills, learn new things, and improve your strengths. We offer a supportive working environment and development opportunities.

Requirements 

The ideal candidate would have the following qualifications and competencies:

  • A relevant educational background, such as Bachelor’s or Master’s degree in, e.g. Pharmacy, Life sciences or Languages
  • Good co-operation and team working skills, but also capability to work independently
  • Strong attention to detail and precision
  • Willing to stick to deadlines
  • A desire to learn and grow
  • Readiness to take responsibility and willingness to develop processes further
  • Proactiveness and solution-orientated mindset
  • Fluent communication and negotiation skills in English. Skills in other languages is an adventage
  • Good skills in MS Office

Hands-on experience of regulatory affairs or other expert work in the pharmaceutical industry is considered an advantage.

Additional Information 

If you think this position is made for you, please send your CV and your application no later than 17th November 2024.

Inquiries can be done by telephone: Kristina Bergström, Senior Regulatory Affairs Manager, tel. +358 50966 7618 on 4th Nov 9:00-11:30, 7th Nov 11:00-12:00 and 14th Nov 12:00-14:30.

We will carry out a security clearance prior to the employment for the selected person.


Orion Corporation operates in more than 30 countries, where we Orionees, 3600 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.

Project Researcher, Bioinformatics – University of Eastern Finland, Kuopio

31.10.2024 | Avoimet työpaikat

https://uef.varbi.com/en/what:job/jobID:762119/type:job/where:4/apply:1

The Faculty of Health Sciences, Biomedicine 

The University of Eastern Finland is inviting applications for a Project Researcher position on the Institute of Biomedicine, Kuopio Campus. The position will be filled  from 1 January 2025 (or as agreed). Please find more information below and submit your application by 30 November 2024.

Role and salary 

We are seeking a Project Researcher with strong skills in computer science, statistics and bioinformatics for a 6-month intern position. The Computational Genomics Lab is led by Dr. Lu Cheng at the Institute of Biomedicine at the Faculty of Health Sciences in Kuopio, Finland. 

The main responsibilities of the Project Researcher include:

  • conducting research in one of the following fields:
    • Nanopore sequencing of proteins
    • Super-enhancer data analysis 
    • Large language model for scRNA-seq data
  • participating in the preparation of research projects and grant applications in your field,
  • reporting and producing high-quality scientific publications, 

The position will be filled for a 6-month term from 1 January 2025 (or as agreed). The position will be filled for a fixed term due to it pertaining to a specific project task. A probationary period is applied to all new members of the staff.  

The salary of the position is determined in accordance with the salary system of the Finnish universities. The salary comprises two elements: a job requirement element and a personal performance element. In these positions, the job-related salary element is based on level 2 of the job requirement level chart, and the personal salary element is 6–50% of the job-related salary element. The estimated monthly salary at the beginning of the employment will be  EUR 2,448– 2,671 /month.
 
Our requirements and expectations

Requirements  

  • A completed or close to completed Master’s degree in a field relevant to the project
    • If the applicant doesn´t have the Master´s degree, the title of the position will be Research Trainee, in which case the job-related salary element is based on level 1 of the job requirement level chart and the personal salary element will be 6–50% of the job-related salary element.
  • Research experience: Demonstrated experience in research
  • Proficiency in programming in Python and R. 
  • Proficiency with Linux, bash
  • Familiarity with machine learning topics
  • Excellent skills in oral and written English.

The following will be considered an advantage:

  • High motivation in research
  • Strong programming skills
  • Experience with machine learning method development.

Your benefits

You will have access to the university’s staff benefits, including  

  • opportunity for flexible multi-location work
  • extensive occupational health care 
  • broad selection of staff training
  • staff discount on lunch in our campus restaurants, as well as on a range of other services  
  • affordable sports services and tax-free bike benefit.

Please read more in the Work at UEF section on our website.  

You will have an opportunity to work in an interesting/meaningful/diverse role as part of our international, creative, participatory and inclusive academic community.    

Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.    

How to apply?

Submit your application by using our electronic application form no later than 30 November 2024 by 24:00 (midnight) Finnish time (UTC+2) 

Please note that you must include the following appendices in your application

  • CV (Template for CV, www-page)  
  • copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas  
  • motivation letter: a detailed letter explaining your interest in the project, how you believe you can contribute to our objectives, and why you consider yourself a strong fit for the role
  • names and contact details of 2 references 

Questions?

For further information on the position, please contact Dr Lu Cheng, +358 50 463 2350,  lu.cheng@uef.fi

For further information on the application procedure, please contact: Human Resources hrbiomed@uef.fi

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 3 090 degree students and about 580 PhD students in the Faculty. The faculty has 800 staff members. 

The University of Eastern Finland (UEF) is the most multidisciplinary university in Finland. Our university employs approximately 3,200 employees, and our community includes approximately 17,000 degree students and 16,000 adult education students. Our campuses are located in Joensuu and Kuopio. We represent the world’s cutting edge of research in many fields and produce research-based knowledge, which is made openly available to benefit everyone. Learn more about our university at www.uef.fi/en. Read also about UEF as a working community and employer and the career stories of our employees.

Type of employmentTemporary position
Contract typeFull time
First day of employment1 January 2025 (or starting date as agreed)
SalaryUniversity salary system
Number of positions1
Full-time equivalent100
CityKuopio
CountyPohjois-Savo
CountryFinland
Reference number5948/01.01.03/2024
ContactLu Cheng, +358504632350
Published14.Oct.2024
Last application date30.Nov.2024

1-3 Doctoral Researches, Biological and Environmental Science – University of Jyväskylä

31.10.2024 | Avoimet työpaikat

https://ats.talentadore.com/apply/doctoral-researcher-positions-biological-and-environmental-science/me1Lgv

Apply latest by 24.11.

Applications are invited for 1-3 fully funded PhD positions in Biological and Environmental Sciences at the University of Jyväskylä. Positions will start on August 1st 2025 or as agreed, for a maximum of fixed term of four years.

The Doctoral Programme in Biological and Environmental Science offers doctoral education in Aquatic Science, Ecology and Evolution Biology, Cell and Molecular Biology and Environmental Science. The selected Doctoral Researcher will be assigned to the appropriate research group in the Department.

1. Determining the mechanism causing intraspecific variation in fungal traits that impact carbon use efficiency in soils, supervisor Carlos Aguilar-Trigueros

Can a single fungal species vary its growth or metabolism? Does that variation impact carbon dynamics? We are looking for one student to address these unanswered, fundamental questions! Fungi play a crucial role in soil carbon dynamics by assimilating carbon during growth—which enhances soil carbon storage—and by releasing CO₂ through metabolism, and this project will answer these questions by measuring how Neurospora crassa adjusts its growth and metabolism in response to genetic differences and phenotypic plasticity. This project is an incredible research opportunity for a PhD student to significantly advance our understanding of fungal ecology and soil carbon dynamics. This PhD program is part of a larger Academy Research Fellowship project focused on predicting fungal contributions to carbon cycling based on their traits. It provides a unique opportunity to test the hypothesis—namely, that because fungi have an adaptable, non-centralized, web-like body, their growth is exceptionally variable. The PhD student chosen for this four-year project will be offered a unique balance of independent and structured work as she or he pursues four integrated objectives: (1) quantifying trait variation in N. crassa, (2) assessing phenotypic plasticity across conditions, (3) disentangling genetic vs. environmental contributions to trait variation, and (4) identifying genetic markers via GWAS. The PhD student chose for this project will gain essential transferrable skills in: (1) trait-based ecological theory; (2) handling living collections of fungi in the lab; (3) trait measurement in controlled environments; (4) advanced image analysis using MatLab; (5) analyzing complex data using R; and (6) Genome-Wide-Association Analysis (GWAS). This exciting opportunity will take place in a highly dynamic ecology lab at JYU and integrates foundational theory with technical, analytical, and cutting-edge methodological skills to address a global ecological concern.

2. The biodiversity drivers of soil microarthropods, supervisor Sten Anslan

We are seeking a dedicated PhD candidate to join our research project on soil biodiversity. This PhD project aims to uncover the drivers of soil microarthropod diversity and their role in regulating soil microbial communities. The candidate will employ techniques such as DNA metabarcoding, as well as microscopy and DNA barcoding to enhance the DNA reference library for soil microarthropods, facilitating high-throughput biomonitoring.

  • For more information, please contact the project leader Sten Anslan

3.  Land use change and browning of lakes – long-term impacts on lake biogeochemistry and communities, supervisor Minna Hiltunen

Browning of freshwater systems (i.e. increase in water color) due to increased leaching of organic matter and iron from the catchment has affected many lakes during the past few decades. One important driver of browning is land use change, for example logging, ditching, and peat mining in the catchment area of the lake. Browning can influence the structure and function of lakes in many ways, such as changing the elemental cycles, or decreasing the diversity and biomass of invertebrates and fish. This PhD project will study how forestry practices have influenced browning of lakes, and what kind of changes this has caused in lake biogeochemistry, production, and biological communities. The study will utilize lake sediment time series from lakes with different histories of forestry practices in their catchment, and investigate the trends of browning in these lakes during the past approximately 100 years. The study sites for the PhD project will be chosen based on GIS analyses and the land use history explored for example from old aerial photographs, remotely sensed forest loss, or historical land use maps. The collaboration network of the project, which includes the Research Council of Finland -funded project Hippicap at JYU, and researchers from Natural Resources Institute Finland (LUKE), Finnish Environmental Institute (SYKE) and several universities in Canada, will provide state-of-the-art methodology for studying lake browning and valuable contacts for the PhD candidate. An eligible candidate should hold a Master’s degree in biology, aquatic sciences, ecology, environmental sciences, geosciences, or forest sciences.

  • For more information, please contact the project leader Minna Hiltunen

4. Colorectal Cancer-Associated Fibroblasts (CAFs) in Tumor Progression, supervisor Tiina Jokela

The project explores the role of cancer-associated fibroblasts (CAFs) in colorectal cancer, focusing on their impact on ECM remodeling, tissue stiffness, metastasis and overall cancer progression. Through multiplex immunohistochemistry, we will analyze CAF phenotypes and their interaction with tumor. Additionally, advanced techniques like Fourier Transform Infrared (FTIR) spectroscopy and Atomic Force Microscopy (AFM) will be used to assess ECM changes and tissue stiffness. Combining these methods, the study aims to uncover how CAFs contribute to tumor progression and metastasis, providing potential therapeutic insights for colorectal cancer.

  • For more information, please contact the project leader Tiina Jokela

5. Natural mucosal viromes in the health of vertebrates, supervisor Reetta Penttinen

In natural environments, bacteria are constantly accompanied by local viromes. These interactions are a key element in maintaining the structure and evolution of microbial communities. In vertebrates, the mucous layers in particular form a central interface for bacteria and phages to counteract. While the importance of mucosal microbiomes, such as those of the human gut, is well established, the role of mucosal virome on vertebrate health has remained poorly understood. In this PhD project, we attempt to address this question by studying the impact of mucins as well as antibiotic treatment on mucosal virome and on bacterial community. The main research questions of this PhD project are: 1) How does the presence of mucin or antibiotics modify the gut virome? 2) How is mucosal virome linked to vertebrate health and does it protect from bacterial pathogens? 3) Does the presence of mucin modify the interactions of phages and their bacterial hosts via CRISPR immunity? The project will utilize gut microcosms and zebra fish infection model to investigate the role of microbial interactions in vertebrate homeostasis.

6. Sustainability challenges in increasing wind power in forested landscapes, supervisor Johanna Yletyinen

The plan to significantly increase wind power construction in Finland’s forested areas has raised concerns about the diverse effects of wind farms on forest wildlife, land use, and local communities, including their role in the decision-making process. However, the negative local effects of wind farms are often defended by citing the critical role of wind energy in the national and global sustainability transformation strategies. This project will investigate the effects of wind farm installations in forests on the resilience of local social-ecological systems and develop an integrated social-ecological framework to guide sustainable wind farm development in forested landscapes. By emphasizing the multi-scalar nature of sustainability transformations, the project will develop solutions for balancing national wind energy goals with local environmental protection and community well-being.

Qualifications

An eligible candidate needs to have 

  • A Master’s degree, or are about to obtain a Master’s degree, in a relevant discipline. 
  • Strong interest to the research project you are applying to.
  • Curiosity and interest in fundamental scientific questions.
  • Ability and motivation to work as part of a team, combined with independence and problem-solving skills.

The tasks of a Doctoral Researcher focus on research aiming at the completion of a doctoral thesis, doctoral studies, assisting teaching tasks, and other related tasks.

The duties, qualification requirements and language skills of a Doctoral Researcher are stipulated by the University of Jyväskylä Regulations and language skills guidelines. The MSc degree required for the position must have been completed before starting the position. A good command of English is required. Doctoral Researcher needs to be also enrolled in the doctoral programme which can be applied with a separate application from the Faculty of Mathematics and Science after selection for the position. The employment starts with a trial period of six months.

We offer

At the University of Jyväskylä, you are a recognized member of our community with a unique opportunity to influence international research. You get to participate in our international and multidisciplinary community where the welfare of each individual is important. At the University of Jyväskylä, we offer a great and lively campus area with opportunities to maintain an active and healthy lifestyle.

Finland has a high standard of living, with free schooling (also in English), affordable childcare, good family benefits, and healthcare. Jyväskylä is located in central Finland amidst Finnish lakes and has excellent opportunities for different nature, outdoor, and sports activities. The city of Jyväskylä is a major educational center and the city has a large student population. As such there is a vibrant cultural scene in the city. To find useful information about the University of Jyväskylä, the City of Jyväskylä, and living in Finland, University’s International Staff Guide.

The initial annual salary will be approximately 30,000 EUR (gross income, including a holiday bonus). With progress of the thesis work, the salary will be revised in accordance with the Collective Agreement of Finnish Universities. The employment starts with a trial period of six months.

How to apply

Please attach the following documents to the online application form in English and in PDF format:

  1. A Curriculum vitae, composed according to good scientific practice and considering the template for researcher´s curriculum vitae by The Finnish Advisory Board on Research Integrity and including contact information of two academics willing to provide a reference
  2. A short and informal motivation/cover letter (max 2 pages), including your research interests, career goals and previous experience and merits in relation to the qualifications for this position. It should be clearly identified the project which is applied for.
  3. Degree certificate (highest degree, or the date of completion the MSc)
  4. Other relevant documents (eg. English language test record) 

At the end of the application form, select the project you are applying to. Research plan is not needed at this point. Applications sent via emails will not be considered.

For more information of the call, please contact professor Varpu Marjomäki, varpu.s.marjomaki@jyu.fi.

In recruitment, we follow the Code of Conduct and Recommendations for the Recruitment of Researchers as defined in the European Charter for Researchers European Charter for Researchers. The University of Jyväskylä is committed to fairness, consistency and transparency in selection decisions, and undertakes the recommendations for the responsible evaluation of a researcher in Finland and DORA-declaration. The application process is transparent, professional and international. We communicate openly with the applicants throughout the recruitment process.

We value equality and diversity in our work community and encourage qualified applicants, regardless of background, to apply for this position.

Apply between 28 October 2024 and 24 November 2024 23:59 (Europe/Helsinki)

Department of Biological and Environmental Science

The research in the Department of Biological and Environmental Science focuses on three core areas: evolutionary biology, natural resources and environment, and biological nanoscience. The Department building, Ambiotica, is an integral part of the University of Jyväskylä’s Ylistönrinne Mathematics and Science Research Complex, which includes buildings of chemistry, physics and nanoscience. Ambiotica houses high quality laboratories for bioscience and experimental facilities for a wide range of biological and chemical analyses as well as highly motivated laboratory personnel.

The University of Jyväskylä is a human-centered environment of 2,500 experts and 14,500 students. Our goal is to create wisdom and wellbeing for all. JYU’s naturally beautiful campus is located in the heart of the city of Jyväskylä. JYU is the third largest employer in Central Finland.

Postdoctoral Researcher, Cardiovascular Genomics – University of Eastern Finland

2.8.2024 | Avoimet työpaikat

https://uef.varbi.com/en/what:job/jobID:735195/type:job/where:123/apply:1

Apply latest by 5th of August

About the job

The University of Eastern Finland is inviting applications for a Postdoctoral Researcher position on the Kuopio Campus. The position will be filled for a two-year term from 1 October 2024 onwards (or as agreed) with the option to extend for an additional 1–2-year. Please find more information below and submit your application by 5 August 2024.

Role and salary

The Cardiovascular Genomics Lab (Kaikkonen Lab) at the A.I. Virtanen Institute, University of Eastern Finland is seeking a highly motivated and skilled Postdoctoral Researcher. This position is part of an ERC-funded project entitled SECRET that aims to unravel the complex genetic and gene regulatory mechanisms underlying atherosclerotic cardiovascular disease (ASCVD).

The SECRET project focuses on exploring the functional impacts of specific ASCVD-associated cis-regulatory variants identified in GWAS studies. The project will initially screen how these variants influence gene regulation in key vascular cells—endothelial cells and smooth muscle cells. Following the identification of key regulatory variants, further experiments will manipulate these genes directly using CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) to observe the effects on broader gene expression patterns and cellular responses. The generated data will be used to identify convergences around gene regulatory networks, helping to uncover the mechanisms, functions, and pathways that underlie ASCVD risk.

The position is being offered as a 2-year appointment with a 1-2 year extension option. The position is filled for a fixed-term due to it pertaining to a specific project task. A probationary period is applied to all new members of the staff.

The salary of the position is determined in accordance with the salary system of Finnish universities. The salary comprises two components: a job-related salary element and a personal salary element. In this position, the job requirement level is based on levels 5-6 on the job requirement level chart for teaching and research staff. The personal salary element is 6–50% of the job-related salary element. Depending on the personal salary element, the salary will be approximately 3,500 -4,500 €/month.

Our requirements and expectations

We invite applications from talented individuals who are highly motivated and passionate about making a transformative impact in cardiovascular research.

Requirements

  • A Ph.D. or equivalent in a field relevant to the proposed project
  • Research Experience: Demonstrable experience in research, preferably within the field of cardiovascular research, genetics, genomics, biotechnology, molecular biology, bioinformatics or a closely related area.
  • Skills: Proficiency in high-throughput genomic methods and data analysis, genetic manipulation tools (e.g. CRISPR), and/or mammalian cell culture.
  • Publications: A strong track record of publications.
  • Communication: Excellent English communication skills, both written and oral.
  • Teamwork: Ability to work effectively as part of an interdisciplinary and international team.
  • Motivation: A passion for scientific research, problem-solving abilities, and a strong desire to contribute to the field of cardiovascular genomics.
  • Autonomy: Candidates should be capable of independent thought and decision-making, demonstrating an ability to lead projects from conception to completion.
  • Supervision experience: The candidate will have the opportunity to supervise MSc and PhD students

Expectations

  • Ability to work effectively as part of an interdisciplinary and international team.
  • A passion for scientific research, problem-solving abilities, and a strong desire to contribute to the field of cardiovascular genomics.

Your benefits

You will have access to the university’s staff benefits, including

  • opportunity for flexible multi-location work
  • extensive occupational health care
  • broad selection of staff training
  • staff discount on lunch in our campus restaurants, as well as on a range of other services
  • affordable sports services and tax-free bike benefit

Please read more in the Work at UEF section on our website.

You will have an opportunity to work in an interesting and meaningful role as part of our international, creative, participatory and inclusive academic community.

Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.

How to apply?

Submit your application by using our electronic application form no later than 5 August 2023 by 24:00 (midnight) Finnish time (UTC+3)

Please note that you must include the following appendices in your application

  • CV (Template for CV , www-page)
  • a list of publications (Instructions, www-page)
  • copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas
  • motivation letter: A detailed letter explaining your interest in the project, how you believe you can contribute to our objectives, and why you consider yourself a strong fit for the role

Questions?

For further information on the position, please contact Professor Minna Kaikkonen-Määttä, tel. +358 29 445 4156, minna.kaikkonen@uef.fi

For further information on the application procedure, please contact HR Controller Tarja Salmi, tarja.salmi@uef.fi, +358 29 4458220 (out of office

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 3 090 degree students and about 580 PhD students in the Faculty. The faculty has 800 staff members.

The University of Eastern Finland (UEF) is the most multidisciplinary university in Finland. Our university employs approximately 3,200 employees, and our community includes approximately 16,000 degree students and 16,000 adult education students. Our campuses are located in Joensuu and Kuopio. We represent the world’s cutting edge of research in many fields and produce research-based knowledge, which is made openly available to benefit everyone. Learn more about our university at www.uef.fi/en. Read also about UEF as a working community and employer and the career stories of our employees.

Työsopimuksen voimassaolo: määräaikainen työsopimus | Työsuhteen luonne: kokoaikainen | Paikkojen lukumäärä: 1 | Työllisyysaste: 100 | Paikkakunta: Kuopio | Maakunta: Pohjois-Savo | Maa: Finland | Ilmoitusnumero: 4113/01.01.03/2024 | Yhteys: Minna Kaikkonen-Määttä +358403552413, Tarja Salmi +358469236724, | Julkaistu: 2024-06-12 | Haku päättyy: 2024-08-05

R&D Scientist, Medical Diagnostics – Canatu, Vantaa

2.8.2024 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3982715391/?refId=e3bab84e-4322-4753-ba99-b4ac2458d392&trackingId=C%2BSrFW6ARnaRJoTLEIksew%3D%3D

Apply latest by 15th of August

About the job

Canatu is a carbon nanomaterial developer creating the most advanced carbon nanotubes for industry-transforming products. The Canatu carbon nanotube (CNT) technology has been created with a unique process that ensures the required versatility and reliability for highly engineered solutions. Canatu partners with forerunner companies, together transforming products for better tomorrows with nano carbon. The company’s focus is in the automotive and semiconductor industries with the portfolio’s core spanning from ADAS heaters to 3D touch sensors and to EUV membranes. The experts at Canatu think big and create impacts on the tiniest scale – nano solutions for massive impact. Canatu’s headquarter is in Finland with sales offices in the US, Japan, and Taiwan. More information on www.canatu.com.

Canatu is further expanding operations and building a passionate team to drive our biosensor development and commercialization. Join us to develop the next-generation medical diagnostics solutions!

We are currently looking for an enthusiastic and highly competent

R&D Scientist, Medical Diagnostics

who will work as an engineering expert in our biosensor team. In this role, you will be contributing to the design, validation and assessment of biosensors and assays. This is a unique and exciting opportunity to join the company where we are passionate about solving world-scale problems with nanoscale innovations. The successful candidate has a passion for innovation, commitment to achieve, and is driven by curiosity. As a person, you strive in a fast-paced changing environment. In this position, you will report to the CTO.

Responsibilities:

  • Research and development of biosensors towards commercial applications
  • Surface chemistry modification for biosensor application
  • Sourcing and implementation of appropriate biorecognition elements, e.g., antibodies or aptamers, to meet the application requirements
  • Perform /analyze testing and verification data according to regulations and standards for manufacturing processes (e.g. cGMP and GPD)
  • Manage work packages and tasks
  • Write technical reports and documents

Our expectations for you:

  • Some experience in development of electrochemical or immuno-based biosensors and assays from academia or industry.
  • Knowledge of biosensors principles, design and basic characterizations including sensor stack related materials, e.g. capillary materials and membranes
  • Knowledge of biochemistry, immunochemistry, enzyme immobilization, DNA, and RNA chemistries
  • Hands-on experience
  • Good written and verbal communication skills in English
  • Ability to learn fast and work independently at the customer interface
  • Solid problem-solving skills, customer-oriented mindset and “can do” attitude
  • Good time management and interpersonal skills
  • MSc or PhD in chemistry, material science, biochemistry, electrical engineering, or some other similar degree in relevant field

What do we offer you?

At Canatu we have substantial growth prospects, and we are constantly seeking innovation. As a rapidly growing company, the roles here are expansive, allowing you to engage in diverse tasks. Our purpose is driven by technology, enabling a multitude of possibilities. As an entrepreneurial company with over 120 employees from about 30 different nationalities, you will be a part of a dynamic and forward-looking scale-up with great team spirit and peer support. At Canatu, the following core values define who we are and who we want to be, guiding us in our day-to-day work:

  • Curiosity to discover provides us with the spark that takes us out into the world to observe and find.
  • Commitment to achieve is how we take those discoveries from ideas to something concrete.
  • Collaboration for impact is required to develop what we create into impactful and meaningful products.
  • Passion for progress keeps us working for new ways to do things for better tomorrows.

Does this resonate? If yes, please apply already today and join us to leave your mark and do the work with an impact.

For further information please contact CTO Ilkka Varjos at +358 400372785 on Friday 9th August between 14-15 or on Monday 12th August between 14-15. Please send your CV and cover letter together with the salary request by August 15th, 2024.

Doctoral Researcher in Microbial Epigenetics – University of Jyväskylä

2.8.2024 | Avoimet työpaikat

https://ats.talentadore.com/apply/doctoral-researcher-in-microbial-epigenetics/mBqQ75

Apply latest by 16th of August

About the job

The Department of Biological and Environmental Science is currently seeking to recruit staff to the position of Doctoral Researcher in Microbial Epigenetics, starting on beginning of September 2024 or as agreed, for a maximum fixed term of four years.

The genetics, epigenetics, and evolution group lead by Ilkka Kronholm studies the properties of mutations and spontaneous epigenetic changes, parental effects, and genetic architecture of complex traits. Our research questions are focused on understanding how different intrinsic and extrinsic factors affect evolutionary adaptation. As model systems we use bacteria, fission yeast, and the filamentous fungus Neurospora crassa.

The researcher will join a Research Council of Finland funded project that studies the role of adenosine methylation in adaptation. Studies in evolutionary epigenetics have largely focused on cytosine methylation in eukaryotes. However, in bacteria adenosine methylation is an important epigenetic mechanism that is known to play a role for example, in bacterial phase variation. We have observed that adenosine methylation changes happen when bacterial populations adapt to a new environment, see for example: Bruneaux et al. 2021. Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens. Epigenetics 17: 861-881   https://doi.org/10.1080/15592294.2021.1966215 and Bruneaux et al. 2022. The effect of a temperature-sensitive prophage on the evolution of virulence in an opportunistic bacterial pathogen. Molecular Ecology 31: 5402-18 https://doi.org/10.1111/mec.16638.

In this project we will study adenosine methylation changes in more detail and estimate genome wide the rates of spontaneous adenosine methylation changes using mutation accumulation experiments and Nanopore / PacBio sequencing. Our group has previously done mutation accumulation experiments in fungi see: Villalba de la Peña et al. 2023. Chromatin structure influences rate and spectrum of spontaneous mutations in Neurospora crassaGenome Research 33: 1-13 https://doi.org/10.1101/gr.276992.122.

In this project we will also characterise different adenosine methyltransferases present in bacterial genomes, and investigate whether adenosine methylation plays any role in antibiotic resistance and its evolution. For general background on adenosine methylation in bacteria see: Sánchez-Romero & Casadesús 2020. The bacterial epigenome. Nature Reviews Microbiology 18: 7-20 https://doi.org/10.1038/s41579-019-0286-2.

The doctoral researcher is expected to contribute to the current project, plan and perform research, write manuscripts and finally a PhD thesis. While the major outlines of the project are fixed, it is possible to tailor parts of the project according to the interests of the candidate, within the overall framework of the project. Participating in limited amount of teaching can also be arranged.

Apply between 25 June 2024 and 9 August 2024 11:45 (Europe/Helsinki)

Who we are looking for

You are the person we are looking for if you have a master’s degree in microbiology, evolutionary biology, genetics, or a related discipline with a strong interest in microbial or evolutionary genetics. While previous experience with microbes is not required, it can be an advantage. Experience in analysis of sequencing (NGS) data can also be an advantage, as well as good computational skills and solid understanding of statistics, and in particular the R environment. Good written and oral communication skills in English are required.

The duties, qualification requirements and language skills of a Doctoral Researcher are stipulated by the University of Jyväskylä Regulations and language skills guidelines. The MSc degree required for the position must have been completed before starting the position. Doctoral Researcher needs to be also enrolled in the doctoral programme which can be applied from the Faculty of Mathematics and Science after selection for the position. A trial period of six months will be used in the beginning of the employment.

Benefits

At the University of Jyväskylä, you are a recognized member of our community with an ample opportunity to be drawn into international research. You get to participate in our international and multidisciplinary community, where everybody’s welfare is essential. You will work in an inspiring and lively campus area and an environment that supports a healthy and active lifestyle. 

Finland has a high standard of living with healthcare, free schooling (also in English), affordable childcare, and good family benefits. The city of Jyväskylä is located in central Finland amidst Finnish lakes and has excellent opportunities for different nature, outdoor, and sports activities. It is a major educational center, whose large student population is responsible for a vibrant cultural scene. To find useful information about the University of Jyväskylä, the City of Jyväskylä, and living in Finland, see the University’s International Staff Guide.

The initial annual salary will be approximately 29,000 EUR (gross income, including a holiday bonus). With progress of the thesis work, the salary will be revised in accordance with the Collective Agreement of Finnish Universities.

Please attach the following documents to the online application form:

  1. Curriculum vitae, composed according to good scientific practice and considering the template for researcher´s curriculum vitae by The Finnish Advisory Board on Research Integrity and including contact information of two people willing to provide a reference.
  2. Cover letter explaining your motivation and research interests.
  3. Relevant certificates / diplomas.

Please submit your application at the latest by 9th of August 2024 11:45 pm (GMT +2) using the online application form.

Eligible candidates will be evaluated based on the submitted documents following the recommendations for the responsible evaluation of a researcher in Finland. Shortlisted candidates will be invited for a personal interview. For further details, please contact: Associate Professor Ilkka Kronholm, ilkka.kronholm@jyu.fi.

We value equality and diversity in our work community and encourage qualified applicants to apply for these positions.

Department of Biological and Environmental Science

The research in the Department of Biological and Environmental Science focuses on three core areas: evolutionary biology, natural resources and environment, and biological nanoscience. The Department building, Ambiotica, is an integral part of the University of Jyväskylä’s Ylistönrinne Mathematics and Science Research Complex, which includes buildings of chemistry, physics and nanoscience. Ambiotica houses high quality laboratories for bioscience and experimental facilities for a wide range of biological and chemical analyses as well as highly motivated laboratory personnel.

The University of Jyväskylä is a human-centered environment of 2,500 experts and 14,500 students. Our goal is to create wisdom and wellbeing for all. JYU’s naturally beautiful campus is located in the heart of the city of Jyväskylä. JYU is the third largest employer in Central Finland.

Postdoctoral Researcher in Microbial Epigenetics – University of Jyväskylä

2.8.2024 | Avoimet työpaikat

https://ats.talentadore.com/apply/postdoctoral-researcher-in-microbial-epigenetics/Z9Lg0l

Apply latest by 16th of August

About the job

The Department of Biological and Environmental Science is currently seeking to recruit staff to the position of Postdoctoral Researcher in Microbial Epigenetics, starting on 1st of September 2024 or as agreed, for a maximum fixed term of three years.

The genetics, epigenetics, and evolution group lead by Ilkka Kronholm studies the properties of mutations and spontaneous epigenetic changes, parental effects, and genetic architecture of complex traits. Our research questions are focused on understanding how different intrinsic and extrinsic factors affect evolutionary adaptation. As model systems we use bacteria, fission yeast, and the filamentous fungus Neurospora crassa.

The researcher will join a Research Council of Finland funded project that studies the role of adenosine methylation in adaptation. Studies in evolutionary epigenetics have largely focused on cytosine methylation in eukaryotes. However, in bacteria adenosine methylation is an important epigenetic mechanism that is known to play a role for example, in bacterial phase variation. We have observed that adenosine methylation changes happen when bacterial populations adapt to a new environment, see for example: Bruneaux et al. 2021. Roles of adenine methylation and genetic mutations in adaptation to different temperatures in Serratia marcescens. Epigenetics 17: 861-881   https://doi.org/10.1080/15592294.2021.1966215 and Bruneaux et al. 2022. The effect of a temperature-sensitive prophage on the evolution of virulence in an opportunistic bacterial pathogen. Molecular Ecology 31: 5402-18 https://doi.org/10.1111/mec.16638.

In this project we will study adenosine methylation changes in more detail and estimate genome wide the rates of spontaneous adenosine methylation changes using mutation accumulation experiments and Nanopore / PacBio sequencing. Our group has previously done mutation accumulation experiments in fungi see: Villalba de la Peña et al. 2023. Chromatin structure influences rate and spectrum of spontaneous mutations in Neurospora crassaGenome Research 33: 1-13 https://doi.org/10.1101/gr.276992.122.

In this project we will also characterise different adenosine methyltransferases present in bacterial genomes, and investigate whether adenosine methylation plays any role in antibiotic resistance and its evolution. For general background on adenosine methylation in bacteria see: Sánchez-Romero & Casadesús 2020. The bacterial epigenome. Nature Reviews Microbiology 18: 7-20 https://doi.org/10.1038/s41579-019-0286-2.

While the postdoctoral researcher is expected to contribute to the current project, and jointly supervise students, there is also the possibility to develop your own interests within the framework of the project or to participate in teaching if the researcher so wishes.

Apply between 25 June 2024 and 16 August 2024 11:45 (Europe/Helsinki)

Who we are looking for

You are the person we are looking for if you have a doctoral (PhD) degree in microbiology, genetics, evolutionary biology, or a related discipline with strong interest in epigenetics or microbial genetics. Previous experience with microbial work is required for this position. Experience in analysis of different types of sequencing (NGS) data, and solid understanding of statistics, and in particular the R environment, is considered an advantage. Good written and oral communication skills in English are required.

The duties, qualification requirements and language skills of a Postdoctoral Researcher are stipulated by the University of Jyväskylä Regulations and language skills guidelines. A good command of English is required, and proficiency to teach in English will be considered beneficial. The PhD degree required for the position must have been completed before starting the position. The employment starts with a trial period of six months.

Benefits

At the University of Jyväskylä, you are a recognized member of our community with an ample opportunity to be drawn into international research. You get to participate in our international and multidisciplinary community, where everybody’s welfare is essential. You will work in an inspiring and lively campus area and an environment that supports a healthy and active lifestyle. 

Finland has a high standard of living with healthcare, free schooling (also in English), affordable childcare, and good family benefits. The city of Jyväskylä is located in central Finland amidst Finnish lakes and has excellent opportunities for different nature, outdoor, and sports activities. It is a major educational center, whose large student population is responsible for a vibrant cultural scene. To find useful information about the University of Jyväskylä, the City of Jyväskylä, and living in Finland, see the University’s International Staff Guide.

The initial annual salary will be approximately 44,000 – 51,000 EUR, gross income, including holiday bonus), depending on the qualifications and experience of the candidate.

How to apply?

Please attach the following documents to the online application form:

  1. Curriculum vitae, composed according to good scientific practice and considering the template for researcher´s curriculum vitae by The Finnish Advisory Board on Research Integrity and including contact information of two people willing to provide a reference
  2. Cover letter explaining your motivation and research interests
  3. A numbered list of publications
  4. Relevant certificates / diplomas
  5. *Research plan should not be included. Due to a technical issue in the web form, please submit your motivation/cover letter here again.

Please submit your application at the latest by 16th of August 2024 11:45 pm (GMT +2) using the online application form.

Eligible candidates will be evaluated based on the submitted documents following the recommendations for the responsible evaluation of a researcher in Finland. Shortlisted candidates will be invited for a personal interview. For further details, please contact: Associate Professor Ilkka Kronholm, ilkka.kronholm@jyu.fi.

We value equality and diversity in our work community and encourage qualified applicants, regardless of background, to apply for this position.

Department of Biological and Environmental Science

The research in the Department of Biological and Environmental Science focuses on three core areas: evolutionary biology, natural resources and environment, and biological nanoscience. The Department building, Ambiotica, is an integral part of the University of Jyväskylä’s Ylistönrinne Mathematics and Science Research Complex, which includes buildings of chemistry, physics and nanoscience. Ambiotica houses high quality laboratories for bioscience and experimental facilities for a wide range of biological and chemical analyses as well as highly motivated laboratory personnel.

The University of Jyväskylä is a human-centered environment of 2,500 experts and 14,500 students. Our goal is to create wisdom and wellbeing for all. JYU’s naturally beautiful campus is located in the heart of the city of Jyväskylä. JYU is the third largest employer in Central Finland.