We are a vibrant research lab of about 16 researchers, including
postdocs, graduate students and highly skilled research assisting
personnel. Our mission is to translate high-impact laboratory
discoveries for the benefit of breast cancer patients. We are seeking an
experienced laboratory manager, available immediately, to work at the
interface of the Klefström lab and several HiLIFE research services,
especially the Helsinki Virus (HelVi) core.
In the Klefström lab the candidate takes care of operational lab
management and maintenance tasks, but also participates in a variety of
research projects. In the HiLIFE HelVi unit the candidate will mainly
focus on the management of the recombinant virus laboratory (BVC)
including biosafety training and generation of lenti- and retroviral
particles for in vitro and in vivo purposes.
We are looking for a lab manager with a higher vocational diploma or a
master’s degree in molecular biology, biotechnology or equivalent. A
successful candidate must have 5+ years of work experience in biomedical
research, excellent communication skills in Finnish and English,
experience in cell culture and molecular and cell biology methods and
competence for operational lab management. Ideally, the candidate has a
license and previous experience in in vivo methods and BSL2 gene
transfer methods. We offer variety of tasks in a teamwork-spirited
environment, as well as excellent possibilities to develop skills in
vivo techniques and in state-of-the-art functional genomics and
translational technologies.
Note! The deadline for the application is December 20th 2019 but the position is filled as soon as a suitable candidate is found.
To apply, please send a cover letter, CV and names of two referees to Research Director Juha Klefström via E-mail: klefstromjobs@gmail.com with the quoting reference Labmanager2019. Closing date: December 20th, 2019.
Targovax
(OSE:TRVX) is a clinical stage immuno-oncology company developing
oncolytic viruses to target hard-to-treat solid tumors. Targovax’s lead
product candidate, ONCOS-102, is
a genetically modified oncolytic adenovirus, which has been engineered
to selectively infect cancer cells and activate the immune system to
fight the cancer. ONCOS-102 is currently being tested in mesothelioma,
melanoma and peritoneal malignancies and has already
shown promising clinical results both as monotherapy and in combination
with chemotherapy and checkpoint inhibitors
Targovax
seeks dedicated, passionate and hardworking individuals who will bring
their experiences, unique perspectives and problem-solving skills to our
team. In return, Targovax cultivates
an environment that rewards and recognizes hard work and provides
opportunities for learning and growth as part of the team. Targovax
aspires to make a difference in the lives of patients by working towards
our mission: Activating the patient’s immune system
to fight cancer! For more information about the company, please visit: www.targovax.com.
Targovax
Oy is currently looking for a CMC scientist to join our Chemistry,
Manufacturing and Control (CMC) team. The position is a fixed term for
one year (1.1.2020 – 31.12.2020). There
may be an option for continuation after the period. Targovax Oy office
is based in Ruoholahti, Helsinki, and the work will demand presence in
the office.
You
will get varied and exciting responsibilities, as you participate in
the development of a new cancer treatment in a motivating environment of
an innovative and active start-up company.
You will join a team of experienced and nice colleagues who will support
you to succeed. The position will report to Director, CMC.
Tasks
Your
main responsibility will be leading the oncolytic adenovirus drug
substance downstream process (purification process based on
chromatography) development and up-scaling activities
at external CMO/CRO collaborators. The key tasks will include designing
experiments with sound scientific rationale, interpreting the results
and steering the process development to obtain the project goals.
You
will also participate in other activities, such as upstream process
(cell culture) development, troubleshooting and risk assessment
activities, CMO sourcing and supervision, analytical
development, clinical supply and regulatory writing. This part of the
work will be tailored based on your experience and interests.
Qualifications:
Scientific mindset
PhD or Master’s degree in biochemistry, bioengineering, biology, chemistry or related scientific discipline
Experience in chromatographic purification techniques and bioprocessing
Fluent in English
Good scientific writing skills
Good team work skills
Flexible attitude
Willingness to work in highly regulated area
Willingness to travel a few days per month
Additional beneficial experience, knowledge and skills:
Fluent in Finnish
Drug development/process development and up-scaling experience
Experience in working with CMOs
Knowledge of working with EU, US GXP and ICH requirements
Experience in virology or cell biology
For further information please contact Director, CMC, Kristiina Hyvärinen by phone (+358-504341270)
on Monday 25.11. at 10-12 or on Monday 2.12. at 15-17 or by e-mail Kristiina.Hyvarinen@Targovax.com.
If you are interested in the position, please submit your CV and application to renate.birkeli@targovax.com
as soon as possible and at latest on Tuesday 3.12.2019.
Only applications and CV in English will be considered.
The
Assistant Professor position is a tenure track, full-time faculty
position at OSU Center for Health Sciences in Tulsa, Oklahoma.
The position offers an exciting opportunity to join an integrated and
innovative learner-centered academic program. The duties of the
Assistant Professor include research, teaching medical and graduate
courses, and service/outreach. Start-up funding is available.
Tampere
University and Tampere University of Applied Sciences create a unique
environment for multidisciplinary high-impact research
and education in technology, health and society. www.tuni.fi/en
Tampere
ImmunoExcellence (TIE) is a multidisciplinary platform for
vaccine-related immunobiology and public health research at Tampere
University. TIE creates a dynamic, interdisciplinary research
environment for strong preclinical, clinical and postlicensure
vaccine-related
research, including breakthroughs in understanding the immune system and
evaluating the population impact of vaccination programs.
The tenure track position with a focus in immunobiology research will be affiliated with the Faculty
of Medicine and Health Technology, MET. The position with a focus in public health research will be affiliated with the Health Sciences Unit (HES) in the Faculty
of Social Sciences, SOC.
We
are seeking outstanding candidates who have a track record of
internationally significant research in the TIE platform
focus areas, such as immunobiology, immunomodulators, clinical vaccine
research and, vaccine-related public health research. However, the
specific area of research focus is open.
We are seeking a motivated and
talented individual for studying the role of transcription factors and
enhancer malfunction in various diseases such as cancer using modern
genome-wide next generation sequencing (NGS) and
CRISPR methods. These include but are not limited to transcription
factor binding and activity (e.g. ChIP-seq), open chromatin (ATAC-seq),
gene expression (bulk and single-cell RNA-seq), and 3D genome
organization (in situ Hi-C). The candidate will be involved
in generation and analysis of genome-wide functional genomics datasets
to understand the epigenetic landscape and enhancer reprogramming in
cancer.
The Enhancer Biology group (https://www.helsinki.fi/en/researchgroups/enhancer-biology)
led by Dr. Biswajyoti Sahu belongs to the Applied Tumor Genomics Program
in the Faculty of Medicine in University of Helsinki. The institute
provides an excellent research environment with strong focus on cancer
research and is very well-equipped with modern
facilities for genomics, proteomics, microscopy and stem cell biology (https://www.helsinki.fi/en/helsinki-institute-of-lifescience/hilife-research-infrastructures).
We offer the position in an ambitious, multi-disciplinary, and
well-equipped group that is comprised of both wet-lab and computational
scientists.
The candidate should have a PhD
degree in any field of life sciences and a good understanding of
biochemistry, genomics experiments and statistics is expected. Prior
experience with mammalian cell culture, expression
systems and molecular biology methods is required, and familiarity with
NGS methods and analysis of high-throughput omics datasets will be an
asset. Candidates with proven track record in terms of publications will
be given preference.
With English as a working
language, excellent oral and written communication skills are required.
Knowledge of Finnish language is not required. The first contract will
be for a period of one year with a six-month trial
period and can be extended further depending on performance. Salaries
are based on the Finnish universities salary system (YPJ) and is in the
range of 40-45,000 euros per annum depending on experience level and
includes good occupational health care, holiday
and pension benefits.
Details on the project and other informal queries are very welcome and should be sent to biswajyoti.sahu@helsinki.fi.
Applications should include a single-PDF file containing:
(1) one-page cover letter describing your research goals, interest and motivation;
we are pleased to announce the Call for Abstracts for The Joint Meeting of the Finnish Connective Tissue Society and the Finnish Society for Cell Biology, which will be held at the Biomedicum Helsinki (Haartmaninkatu 8, lecture room 3), on February 13th, 2020. Please see the attached file for more information.
The Finnish Connective Tissue SocietyThe Finnish Society for Cell Biology
Tutkijatohtori tai
projektitutkija immuunisäätelyn tutkimukseen molekulaarisen
systeemi-immunologian ryhmään Turun Biotiedekeskukseen
Akatemiaprofessori Riitta Lahesmaan ohjaamassa monialaisessa
kansainvälisessä tutkimusryhmässä Turun Biotiedekeskuksessa on avoinna
tehtävä immuunisäätelyn tutkimuksessa (https://bioscience.fi/research/molecular-systems-immunology/profile/). Etsimme motivoitunutta tutkijatohtoria tai projektitutkijaa, jolla on mahdollisuus jatkaa työtä väitöskirjatyöntekijänä.
Häiriöt immuunijärjestelmässä ja lymfosyyttien toiminnassa
johtavat tulehduksellisiin sairauksiin kuten nivelreumaan ja tyypin 1
diabetekseen. Projektissa selvitetään immuunivälitteisten sairauksien
syntymekanismeja tavoitteena kehittää yksilöllisiä hoitomuotoja
tulevaisuudessa.
Rekrytoivan organisaation kuvaus
Ryhmämme tutkii ihmisen immuunijärjestelmän säätelyä
tavoitteena ymmärtää immuunivälitteisten sairauksien syntymekanismeja.
Tämä on edellytys näiden tautien ja hoidon kehittämiseksi. Tutkimme mm.
lymfosyyttien epigeneettistä ja transkriptionaalista säätelyä
molekyylitasolla.
Turun Biotiedekeskus (https://bioscience.fi)
on Turun yliopiston ja Åbo Akademin yhteinen erillinen laitos.
Keskuksen tehtävä on edistää korkeatasoista tutkimusta ja koulutusta.
Turun Biotiedekeskus tarjoaa moderneja teknologioita ja huippuosaamista
mm. seuraavilla tutkimuksen aloilla:yksisoluanalyysi, NGS,
epigenomiikka, proteomiikka, laskennallinen biologia ja
solunkuvantaminen.
Hakijoilta edellytetään:
Soveltuvaa tohtorin tutkintoa (erikoistutkijan/tutkijatohtorin
tehtävä) tai soveltuvaa maisterin tutkintoa (projektitutkijan tehtävä)
esim. luonnontieteiden tai biolääketieteen alalta
Kykyä oma-aloitteiseen työskentelyyn ja erinomaisia vuorovaikutustaitoja (sekä suullinen että kirjallinen taito)
Tieteellisiä julkaisuja korkeatasoisissa kansainvälisissä lehdissä
ainakin yhdellä seuraavista aloista: immunologia, molekyyli- ja
solubiologia, autoimmuniteetti, genetiikka, epigenomiikka
(tohtoritutkijan tehtävä)
Erinomaisia tietoja ja taitoja molekyyli- ja solubiologiassa sekä vahvaa taustaa epigenetiikassa.
Käytännön kokemus epigenomiikan tekniikoista ja tähän liittyvästä bioinformatiikasta sekä immunologiasta katsotaan eduksi.
Hakemus
Palkka määräytyy yliopistojen työehtosopimuksen mukaisesti.
Tehtävät kuuluvat tutkimushenkilökuntaan. Tutkijatohtorin keskimääräinen
palkka on 2600 -3600 eur/kk (tai 3100 – 4200 eur/kk kokemuksesta riippuen) ja projektitutkijan palkka on keskimäärin 2150 – 2600 eur/kk.
Tehtävä alkaa aikaisintaan 1.1.2020. Aloitusajankohta on
neuvoteltavissa. Tehtävä täytetään alustavasti kahden vuoden ajaksi,
mutta saattaa jatkua vielä vuoden ajan. Tehtävässä on kuuden kuukauden
koeaika.
Hakemukseen tulee liittää ansioluettelo, julkaisuluettelo,
luettelo valikoiduista julkaisuista ja kolmen suosittelijan
yhteystiedot. Lisäksi erikoistutkijan/tutkijatohtorin tehtävää hakevien
tulee liittää hakemukseen akateeminen portfolio (https://www.utu.fi/fi/yliopisto/tule-meille-t%C3%B6ihin/akateeminen-portfolio)
Lisätietoja avoimesta tehtävästä antaa Prof. Riitta Lahesmaa,
email: riitta.lahesmaa(at)utu.fi ja hakuprosessista
henkilöstöasiantuntija Paula Luoma paula.luoma(at)utu.fi.
Postdoctoral Researcher position (fixed-term) for the period of 1 January 2020 – 31 December 2021.
The start of employment is negotiable. The position is fixed-term for
24 months with a possibility for extension. Trial period is 4 months.
We are seeking a highly motivated computational biologist to join the
research group of Dr Teemu Niiranen (Department of Clinical Medicine)
as a Postdoctoral Researcher. We work on a wide range of topics with a
current focus on multi-omics analysis in large-scale population cohorts.
The research can comprise both applied and methodological aspects
depending on the candidate’s interests and expertise.
The duties of Postdoctoral Researcher include the analysis of
population-level omics data (genomics, metagenomics, metabolomics etc.)
aiming at groundbreaking biological discoveries. The key data sources
include comprehensively phenotyped, large national and international
human cohorts whose plasma and/or fecal samples have been analyzed in
leading laboratories using high-throughput (metagenomic) sequencing
and/or state-of-the-art mass spectrometry. Different project areas
related to multi-omics data integration, analysis of longitudinal cohort
data, and the discovery of personalized disease biomarkers are
available.
Qualification Requirements
Qualification
requirements for the position of a Postdoctoral Researcher are stated in
the Rules of Procedure of the University of Turku. Postdoctoral
Researcher is required to have an applicable doctoral degree. They
should also be able to conduct research independently and possess
teaching skills required in the position.
A suitable candidate has:
PhD in Biostatistics, Bioinformatics, Computational Biology, Computer Science, Biology, Mathematics, Medicine or a related field
Relevant background knowledge including proven bioinformatics skills and a solid publication track record
Experience in statistical data analysis, integration, and visualization
Fluency in at least one data science language (such as Python, R, or Julia)
Ability to work both independently and in a team
Willingness to learn new and multidisciplinary skills as needed
Good communication and interpersonal skills and English language skills
Good scientific writing skills
We also appreciate the following:
Familiarity with processing genomic, metabolomic, and metagenomic data
Experience with Linux/Unix environment
Experience with computing clusters, pipelines of batch jobs or cloud- and high-performance computing
Salary
The salary is determined in accordance
with the salary system for universities. The salary of Postdoctoral
Researcher is at levels 4–6 on the job demands chart of teaching and
research personnel. The job-related salary element is 2535,20–3423,25
euros per month. In addition, a personal salary element will be
paid. The personal salary element is a maximum of 50 % of the
job-related salary element.
Why Join Us
We are a team of young scientists
with a solid track record of successful mentoring, inter-institutional
international collaborations in multi-disciplinary research ranging from
classical clinical epidemiology to population-level genetics in
hundreds of thousands of individuals. Our collaborators for this project
come from several top five universities in the world, allowing for
excellent networking opportunities with leading researchers from a wide
spectrum of fields.
How to Apply
Application deadline has been extended until November 29, 2019 (23:59).
Previously submitted applications will be taken into consideration in
the recruitment process.The applications must be submitted via the
electronic application form of the University of Turku. A link to the
application system is available at the beginning of this announcement
(‘Apply for the job’). The application should be written in English and
include a motivation letter (one page), CV (max 4 pages), list of
publications, copies of relevant degree certificates, and contact
information of 1-2 referees.
For further information about the position, please contact Dr. Teemu Niiranen (teemu.niiranen@utu.fi). For possible technical support with the application system, please contact HR Specialist Henna Huovinen (henna.huovinen@utu.fi, tel. +358 50 382 1869).
Tohtorikoulutettavan / projektitutkijan tehtävä dosentti Kaisa Ivaska-Papaioannoun tutkimusryhmässä
Turun yliopiston biolääketieteen laitoksessa on haettavana
tohtorikoulutettavan määräaikainen tehtävä dosentti Ivaska-Papaioannoun
tutkimusryhmässä. Tehtävä sisältyy Suomen Akatemian rahoittamaan
tutkimushankkeeseen, jossa tutkitaan luuston erittämien
säätelytekijöiden merkitystä energia-aineenvaihdunnassa.
Luu on metabolisesti aktiivinen kudos, joka erittää endokriinisesti
vaikuttavia tekijöitä eli osteokiinejä. Osteokiinit säätelevät mm.
glukoosiaineenvaihduntaa eläinmalleissa, mutta niiden merkitys ihmisellä
tunnetaan heikosti. Tutkimusprojektin tavoitteena on tunnistaa
verenkierrossa ja luuytimessä esiintyviä osteokiinejä ja tutkia niiden
säätelyä, merkitystä ja diagnostista käyttöä.
Työtehtäviin sisältyy soluviljelyä, molekyylibiologiaa,
proteiinianalytiikkaa sekä potilasnäytteiden ja koe-eläinten käsittelyä.
Kaikki aiempi työkokemus ja vahva osaaminen edellä mainituista
tekniikoista/menetelmistä katsotaan hakijalle eduksi. Ylempi
korkeakoulututkinto esimerkiksi solubiologian, biolääketieteen tai
biokemian alalta antaa parhaimmat edellytykset tehtävässä menestymiseen.
Turun yliopiston johtosäännön mukaan tohtorikoulutettavan tehtävään
otettavalta edellytetään ylempää korkeakoulututkintoa ja hyväksyttyä
tutkimussuunnitelmaa. Lisäksi edellytetään korkeakoulututkinnon
suorittamisen yhteydessä tai muutoin osoitettua kykyä ja motivoitumista
jatko-opintoihin ja tohtorin tutkinnon suorittamiseen
tutkimussuunnitelman mukaisesti. Mikäli tehtävään valittavalla ei ole
tohtorintutkinnon opinto-oikeutta häntä tehtävään valittaessa, tehtävä
täytetään aluksi nimikkeellä projektitutkija.
Tehtävässä noudatetaan kuuden (6) kuukauden koeaikaa.
Tehtävä täytetään 1.1.2020 alkaen tai sopimuksen mukaan. Tehtävä
täytetään 2-vuotiskaudeksi. Projektitutkijan/tohtorikoulutettavan
tehtäväkohtainen palkkaus määräytyy yliopistojen palkkausjärjestelmän
mukaisesti. Väitöskirjaa päätyönään tekevien henkilöiden osalta
lähtökohtana on, että palkkaus määritellään työsuhteen alussa
vaativuustasolle 2. Palkka on alkuvaiheessa vähintään 2155,29 e/kk.
Tehtävään on sähköinen haku (https://www.utu.fi/en/university/come-work-with-us/open-vacancies). Haku päättyy perjantaina 29.11.2019 (klo 23:59). Hakemukseen
tulee liittää enintään yhden sivun pituinen englanninkelinen
motivaatiokirje, CV ja kahden suosittelijan yhteystiedot (nimi,
työpaikka, sähköposti).
Tehtävän sisällöstä lisätietoja antaa dosentti Kaisa Ivaska-Papaioannou, p. +358 504076533.
Tehtävän hakuprosessista, palkkauksesta ja laitoksesta lisätietoja antavat
henkilöstösihteeri Päivi Aalto, p. + 358 50 313 6830 tai
henkilöstöasiantuntija Heli Törmänen, p. + 358 50 5625 937
Em. henkilöt tavoittaa sähköpostitse osoitteella etunimi.sukunimi (at) utu.fi
Positions in Cell & Developmental Biology and/or
Bioinformatics
Postdoctoral and/or PhD positions are available at the Institute of
Biotechnology, University of Helsinki, in the laboratory of Dr. Nicolas
Di-Poi. Our laboratory (http://www.biocenter.helsinki.fi/bi/di-poi/)
is studying the evolution and development of craniofacial tissues in
non-classical reptile model organisms displaying an exceptional array of
morphologies and regenerative capacities. This is a new and exciting
research field, with the goals to elucidate the developmental mechanisms
of evolutionary changes but also to provide an evolutionary context to
the key signaling pathways of tissue regeneration.
The research projects include complementary state-of-the-art methods,
including cell biology, molecular embryology, high-throughput omics,
geometric morphometrics and functional studies, and they offer an
interdisciplinary environment for research training (see e.g., Nature
Communication (in press), eLife 8:e47702 (2019), Nature Communication
9:376 (2018), Science Advances 2:e1600708 (2016)). The exact topic of
research projects will be discussed in detail during interview.
The successful Doctoral and/or Postdoctoral candidates will have a
genuine interest in multidisciplinary research and will hold an
excellent Master Degree (or equivalent) and/or PhD in Biology with a
specialization in Cell & Developmental Biology and/or
Bioinformatics. In addition, the Postdoctoral candidate will have a
proven record of excellence in the above-mentioned research areas,
whereas the Doctoral candidate will have a strong potential for
excellence in research. Previous experience with multi-omics data
analysis and wet-lab work would be an asset for the Bioinformatics
position.
The Institute of Biotechnology (BI) at the University of Helsinki is
an independent research institute within HiLIFE Helsinki Institute of
Life Science (https://www.helsinki.fi/en/helsinki-institute-of-life-science)
with a mission to increase knowledge in biotechnology and
multidisciplinary bioscience and use this for the benefit of society.
HiLIFE and BI offer state-of-the-art core facilities in microscopy,
imaging, model organisms, omics technologies, genome editing,
histotechnology and bioinformatics.
The salary is defined in accordance with the University salary system
for teaching and research personnel. The positions could start as early
as January 2020 or as agreed with the selected candidates. The
positions are fixed-term of 2-4 years with possible extension. A trial
period of six months will be applied.
To apply, please send (in a single pdf document) a cover letter
describing your previous research and motivation, your detailed CV
including a list of publications, as well as contact information for at
least 2 references (including Master and/or PhD supervisor) through the
University of Helsinki electronic recruitment system by clicking on the
Apply link below. Internal applicants (i.e., current employees of the
University of Helsinki) please submit your applications through the SAP
HR portal. The deadline for the applications is December 31, 2019, but
candidates will be considered until the position is filled.
For more information, contact Dr. Nicolas Di-Poi
(nicolas.di-poi(a)helsinki.fi). In case you need technical support with
the recruitment system, please contact recruitment(at)helsinki.fi.
The University of Helsinki, founded in 1640, is one of the leading
multidisciplinary research universities and ranks among the top 100
international universities in the world. It is currently investing
heavily in life sciences research. The University of Helsinki has an
international academic community of 40,000 students and staff members,
and it offers comprehensive services to its employees, including
occupational health care and health insurance, sports facilities, and
opportunities for professional development.
