Open position for a CMC scientist, Targovax Oy25.11.2019
Open position: CMC scientist, Targovax Oy
Targovax (OSE:TRVX) is a clinical stage immuno-oncology company developing oncolytic viruses to target hard-to-treat solid tumors. Targovax’s lead product candidate, ONCOS-102, is a genetically modified oncolytic adenovirus, which has been engineered to selectively infect cancer cells and activate the immune system to fight the cancer. ONCOS-102 is currently being tested in mesothelioma, melanoma and peritoneal malignancies and has already shown promising clinical results both as monotherapy and in combination with chemotherapy and checkpoint inhibitors
Targovax seeks dedicated, passionate and hardworking individuals who will bring their experiences, unique perspectives and problem-solving skills to our team. In return, Targovax cultivates an environment that rewards and recognizes hard work and provides opportunities for learning and growth as part of the team. Targovax aspires to make a difference in the lives of patients by working towards our mission: Activating the patient’s immune system to fight cancer! For more information about the company, please visit: www.targovax.com.
Targovax Oy is currently looking for a CMC scientist to join our Chemistry, Manufacturing and Control (CMC) team. The position is a fixed term for one year (1.1.2020 – 31.12.2020). There may be an option for continuation after the period. Targovax Oy office is based in Ruoholahti, Helsinki, and the work will demand presence in the office.
You will get varied and exciting responsibilities, as you participate in the development of a new cancer treatment in a motivating environment of an innovative and active start-up company. You will join a team of experienced and nice colleagues who will support you to succeed. The position will report to Director, CMC.
Your main responsibility will be leading the oncolytic adenovirus drug substance downstream process (purification process based on chromatography) development and up-scaling activities at external CMO/CRO collaborators. The key tasks will include designing experiments with sound scientific rationale, interpreting the results and steering the process development to obtain the project goals.
You will also participate in other activities, such as upstream process (cell culture) development, troubleshooting and risk assessment activities, CMO sourcing and supervision, analytical development, clinical supply and regulatory writing. This part of the work will be tailored based on your experience and interests.
- Scientific mindset
- PhD or Master’s degree in biochemistry, bioengineering, biology, chemistry or related scientific discipline
- Experience in chromatographic purification techniques and bioprocessing
- Fluent in English
- Good scientific writing skills
- Good team work skills
- Flexible attitude
- Willingness to work in highly regulated area
- Willingness to travel a few days per month
Additional beneficial experience, knowledge and skills:
- Fluent in Finnish
- Drug development/process development and up-scaling experience
- Experience in working with CMOs
- Knowledge of working with EU, US GXP and ICH requirements
- Experience in virology or cell biology
For further information please contact Director, CMC, Kristiina Hyvärinen by phone (+358-504341270) on Monday 25.11. at 10-12 or on Monday 2.12. at 15-17 or by e-mail Kristiina.Hyvarinen@Targovax.com.
If you are interested in the position, please submit your CV and application to firstname.lastname@example.org as soon as possible and at latest on Tuesday 3.12.2019.
Only applications and CV in English will be considered.