Doctoral Student in Development of Biosensors for Glioma Treatment
The University of Oulu is one of the largest universities in
Finland. With about 14 000 students and approximately 3 000 employees it
is a vibrant international scientific community. By combining
multidisciplinary research and education, high-level infrastructure and
wide cooperation with international research and educational institutes,
companies and the public sector it has created a significant research
and innovation hub of “Science with Arctic Attitude”. More information .
The position is located in the Faculty of Biochemistry and Molecular Medicine of the University of Oulu (
Subject Field And The Description Of The Position
Glioblastoma Multiforme (GBM) is the most malignant primary
brain tumor with a median survival time of little bit more than one
year. High complexity of GBM requires development of novel diagnostic
and therapeutic approaches combining molecular oncology, cell biology,
nanobiology, and bioingeneering. The project aims to develop such
approaches by generating implantable 3D cell organoids. Various in vivo
and in vitro assays, OMICS studies, molecular cloning and analysis of
secreted extracellular vesicles will be applied in the current project.
The details of the research project will be mutually agreed upon, based
on the qualifications, interests, and expertise of the candidate.
Candidates with expertise on neurobiology and solid knowledge and
working experience with cell biology and/or molecular biology will be
preferred.
The duration of the position is initially for 2 years with the
possibility to be extended for 2 more years. The starting date is July
1, 2019, or as soon as possible thereafter.
Required Qualifications And Assessment
The successful applicant must hold a recent MSc degree in
life sciences. Candidates whose master thesis will be submitted by the
application deadline will also be eligible. Fluent oral and written
English skills as well as good communication and teamwork skills are
required. Demonstrated experience in writing scientific publications,
potential in acquiring supplementary funding and teaching experience
will be taken as merits.
A six-month trial period will be effective in the beginning of a contract.
Salary
The salary is in accordance with the University salary system
(for teaching and research personnel) levels 2-4. In addition, there is a
share increase at most, 50% of the base salary, which is based on
personal achievements and performance.
Application Procedure
The following documents must be attached to the application (in English)
Motivation letter (1 – 2 pages)
CV with the names and contact details of 2 – 3 referees
Full publication list
Copies of relevant official degree
Applications, together with all relevant enclosures,
must be submitted using the electronic application form by May 15 st ,
2019. Applications sent by email will not be considered.
Interview
The top candidates for the post may be interviewed and asked to present their scientific work and experience.
For Further Information Regarding The Filling Of This Post
Dr Seppo Vainio, Professor, e-mail: seppo.vainio(at)oulu.fi
Dr Anatoliy Samoylenko, Adj. Professor, e-mail: anatoliy.samoylenko(at)oulu.fi
Tiina Hurskainen, HR Manager, email: tiina.hurskainen(at)oulu.fi
Thermo Fisher
Scientific Inc. (NYSE: TMO) is the world leader in serving science, with
revenues of $20 billion and 67,000 employees in 50 countries. Our
mission is to enable our customers to make the world healthier, cleaner
and safer. We help our customers accelerate life sciences research,
solve complex analytical challenges, improve patient diagnostics and
increase laboratory productivity. Our four premier brands – Life
Technologies, Thermo Scientific, Fisher Scientific and Instrument and
Enterprise Services – offer an unmatched combination of innovative
technologies, purchasing convenience and comprehensive support.
A
driven Product Manager who will manage a portfolio of on-market swine
diagnostic products, seek a deep understanding of customer needs, and
assist in developing the animal health roadmap. S/He will serve as
product champion and be responsible for life cycle management, training,
and support.
Responsibilities:
Manage
the assigned on-market swine product portfolio and the overall product
life cycle including determining discontinuation and/or product refresh.
Define product line strategy based on customer needs, market research and business unit goals
Understand
customer needs then translate them to product specifications that can
be leveraged in an effective go-to-market strategy.
Work cross-functionally to ensure revenue, margin, customer satisfaction, and growth goals are achieved
Forecast sales, guide worldwide pricing, and work with market development on product demand generation strategies
Contribute to fiscal planning and budgeting as it relates to growth and evolution of the product portfolio
Provide ongoing product Sales training and customer support.
Work
as part of a dynamic team of R&D, program management, marketing,
technical, and business development professionals to execute our common
mission
Serve as a key liaison between internal customers
(Sales, R&D, Marketing, Manufacturing, etc) and external customers
(end users, suppliers, etc).
May be required to perform other related duties as required and/or assigned
*Minimum Qualifications (must have):
Bachelor’s Degree (B.S./B.A.) in a scientific discipline (molecular biology, genetics or biochemistry preferred).
At least five years of relevant experience in product management and/or strategic marketing.
Understanding of production animal industry
Willing to travel and work with global teams
Proficient
in understanding, analyzing and summarizing comprehensive and complex
technical, financial, market and research information/data.
Strong communication skills
Very good English skills
Understanding of product management and marketing.
Is customer-centric and keenly aware of markets, trends and competitors
Greets challenge and change as opportunity
Inspires, motivates and collaborates with others
Ability to travel globally 30-40% of time
*Preferred Qualifications (nice to have):
MBA a plus but not required.
Thermo
Fisher Scientific is an EEO/Affirmative Action Employer and does not
discriminate on the basis of race, color, religion, sex, sexual
orientation, gender identity, national origin, protected veteran status,
disability or any other legally protected status.
Etsimme tiedonjanoista tutkijaa vakituiseen työsuhteeseen kehittämään
vasta-aineita diagnostiikkateollisuuden tarpeisiin. Tarjoamme
monipuolisia alan työtehtäviä osana työstään innostunutta
tuotekehitystiimiä. Tutkijan työhön kuuluu uusiin projekteihin liittyvää
tieteellisen tiedon hakua ja yhdistämistä sekä vasta-aineiden erilaista
immunokemiallista karakterisointia, mm. ELISA-menetelmillä ja
BLI-teknologiaa hyödyntäen. Myös immunisointien suunnittelu ja
toteuttaminen kuuluvat tehtävään. Koesuunnittelu,
tuotekehityslaboranttien ohjeistaminen, tulosten tulkinta sekä
raportointi ovat oleellinen osa työtä.
Edellytämme:
kokemusta immunologisista menetelmistä sekä niiden kehittämisestä
reipasta ja huolellista otetta työhön, organisointikykyä, ryhmätyötaitoja ja paineensietokykyä
kykyä selkeään ja tarkkaan dokumentointiin
erinomaista suomen ja englannin kielen taitoa
ylempää korkeakoulututkintoa biokemiasta, bioteknologiasta tai vaihtoehtoisesti tehtävään soveltuvalta alalta
Arvostamme:
kokemusta BLI-teknologiasta
laatujärjestelmien tuntemusta
kokemusta koe-eläintöistä
Hakemukset palkkatoiveineen 12.5.2019 mennessä.
Lisätietoja tehtävästä antaa Teknologiapäällikkö Suvi Eklin puh. 040
8305 355, perjantaina 3.5. klo 13:30 – 14:30 sekä torstaina 9.5. klo
9:00–10:00.
Työ on vakituinen. Työn aloitus sopimuksen mukaan.
Regulatory Affairs Specialist / Assistant Vantaa, Finland
Our
in vitro diagnostic medical devices are regulated products which need
marketing authorization before sales can commence. We are looking for a Regulatory Affairs Specialist /Assistant to
coordinate product registrations in co-operation with our commercial
organization and distributors. The selected candidate will work as an
integral part of a multidisciplinary Quality Assurance and Regulatory
Affairs team to coordinate and compile product registration packages to
e.g. India and other Asia-Pacific countries. This is a fixed-term
position for approximately 3-4 months.
What can we offer
Opportunity
to gain experience in regulatory affairs and know-how in international
regulations that is a core competence in medical device industry
Work in a multi-disciplinary and international setting both with Thermo Fisher Scientific colleagues and our customers
Possibility
to work with our diverse in-vitro medical device product portfolio
including clinical chemistry products and analyzers as well as
laboratory automation solutions
How you’ll get there
M.Sc
or B.Sc degree in microbiology, biology, analytical chemistry,
biochemistry, engineering or related field, or a Student of the
mentioned scientific disciplines
Motivation to learn and interpret different regulations related to in vitro diagnostic medical device industry
Excellent verbal and written communication skills in English
Sound organizational skills and attention to detail in documenting
Self-driven attitude with persistence to take projects to the completion
Please send in your application, including a cover letter and CV. Please apply via https://jobs.thermofisher.com/
by 12.5.2019. Reference: 93305BR. Please apply as soon as possible, the
position will be filled as soon as suitable candidate is found.
Kuopio Center for Gene and
Cell Therapy (KCT) is a world-renowned research institute located in
Kuopio, Finland. Our mission is to conduct high-level research on basic
and translational fields of gene- and cell therapy. The center’s niche
is in the interface between academic research and the commercial
biotechnology industry. KCT provides an exciting environment for applied
research, discovering, establishing and developing them through Phase I
clinical trials and utilizing some of the most advanced analytical and
mechanistic proof-of-principle approaches in the sector.
We
are seeking for two enthusiastic, highly motivated and skilled
candidates with a background in disease or tumor biology, immunology and
biomarker research for Senior Scientist (post-doctoral) role in
Immunotherapy Program in Kuopio Center for Gene and Cell Therapy.
Successful candidates will have an opportunity to work in one or more of
the areas as project manager: T cell and NK cell biology, tumor
microenvironment and/or discovery of novel tumor targets. The candidate
will contribute to the projects experimentally and scientifically,
provide his/her expertise, take-leading role in internal reporting and
continue in a laboratory-focused role. The candidate will have a proven
track record of scientific productivity and ability to participate in
multidisciplinary and innovative research. The individual will
participate in strategic discussions, national and international
collaborations and coordinate project activities.
The
selected candidates will be focused in work leading to the development
of novel immunotherapies. The responsibilities include:
Effectively collaborate within the research center and national/international collaborators.
Lead the design and implementation experimentation.
Supervise young scientists and technicians working in the project.
Generate,
analyze and interpret data. Demonstrate a high level of initiative in
troubleshooting experiments and accurate data analysis. Objectively
interpret data and provide conclusions regarding project results and
direction.
Actively report research results and novelties in the field.
Qualifications:
PhD in immunology, molecular/cell biology, cancer biology,
pharmaceutical sciences or biomarker discovery OR MSc with at least 10
years of relevant experience. Knowledge on high-throughput
experimentation and large data analysis is positively evaluated. Strong
hands-on technical skills (e.g. primary cell isolation and culture, flow
cytometry, live cell imaging) and reporting in research. Ability to
multitask, manage and develop complex projects. Effective written and
spoken English language skills. Excellent interpersonal and teamwork
skills.
We offer an inspiring
multicultural environment, constructed of our enthusiastic, highly
skilled and experienced personnel in gene and cell therapy. Kuopio
Center for Gene and Cell Therapy has established working links with the
gene and cell therapy manufacturer FinVector, the A.I. Virtanen
Institute for Molecular Sciences, the University of Eastern Finland, the
National Laboratory Animal Center, and Kuopio University Hospital.
These are situated on the same Kuopio health science focused campus, the
capability of which to undertake gene and cell therapy research is made
complete by the presence of the office of the Finnish Medicines Agency
(Fimea). Finland has been ranked as the happiest country in the world
and vibrant Kuopio, is rated as Finland’s best city to live in. It
offers a safe living environment, friendly atmosphere and clean nature.
More
information Cell Therapy Unit Director Tuija Kekarainen (tel.
+358405376603 or tuija.kekarainen@kct.fi) and HR Director Johanna
Pirinen (Johanna.pirinen@kct.fi).
Please send your application before 20th May 2019.
Odotellessamme ensimmäisen, uudistuneen Solubiologi-lehden ilmestymistä, päätimme haastatella uutta lehden päätoimittajaa, Jenny Joutsenta:
Moikka Jenny! Kertoisitko vähän itsestäsi ja siitä, miten olet päätynyt Solubiologi-lehden päätoimittajaksi?
”Heippa! Olen Jenny Joutsen, 34-vuotias solubiologi Turusta. Alun perin olen kotoisin Perämeren rannalta Kemistä, josta muutin Turkuun vuonna 2004 opiskelemaan biologiaa Turun yliopistoon. Tällä hetkellä työskentelen Åbo Akademin solubiologian osastolla ja tutkin lämpösokkitekijöitä ja solustressiä. Päädyin Solubiologi-lehden päätoimittajaksi edellisen päätoimittajan Sebastian Landorin sekä yhdistyksen puheenjohtajan Elina Siljamäen pyynnöstä. Pidän paljon kirjoittamisesta ja tekstien lukemisesta, joten ajattelin että tässäpä oiva mahdollisuus kehittää molempia taitoja. Vapaa-aikanani luen paljon sanomalehtiä ja kirjoja, retkeilen perheeni kanssa luonnossa ja haaveilen Arktisen tutkimuskeskuksen perustamisesta.”
Solubiologi-lehti on uudistunut toden teolla, ja odotamme uuden kevään numeron ilmestymistä kovasti. Miten kuvailisit lehteämme lyhyesti jäsenyyttämme harkitseville, jotka eivät lehteämme ennestään tunne?
”Lehti on tosiaan käynyt tänä keväänä läpi mittavan uudistuksen, josta kiitän suuresti uutta taittajaamme Joanna Pylvänäistä. Sisällöllisesti lehdessä on nyt enemmän lyhyitä tekstiosioita, kuten kolumni sekä kuukauden solubiologin esittely, joiden kautta lehteen on aiempaa helpompi tutustua. Huomattavaa myös on, että lehdessä julkaistaan ainoastaan suomen- ja ruotsinkielisiä artikkeleita, minkä vuoksi se on erityisen tärkeä osa kotimaista solubiologista ammattikirjallisuutta.”
Mikä on sinun mielestäsi parasta uudistuneessa lehdessämme?
”Ajankohtaiset tiedeuutiset, houkutteleva artikkelikokonaisuus sekä taidokas ja nykyaikainen ilme.”
Olemme julkaisseet lehdessämme mielellämme myös opinnäytetöitä. Ovatko opiskelijoiden kirjoittamat artikkelit edelleen tervetulleita uudistuneeseen Solubiologiin? Saako artikkeleista edelleen kirjoituspalkkion?
”Ehdottomasti kyllä! Olen henkilökohtaisesti pyrkinyt kannustamaan juuri opiskelijoita kirjoittamaan artikkeleita lehteemme, sillä mielestäni kirjoittamista ei voi koskaan harjoitella liikaa. Kattavasta julkaisuluettelosta on runsaasti hyötyä myös esimerkiksi jatko-opinnoissa, joten artikkeleiden kirjoittamisesta on taatusti etua myös ihan käytännön tasolla. Jokaisesta kirjoitetusta artikkelista saa 100 e suuruisen kirjoituspalkkion.”
Onko sinulla mielessäsi vielä joitain visioita, joita haluaisit lähteä toteuttamaan lehdessämme toimituskunnan kanssa?
”Visioita on aina! Suurin ja pitkäaikaisin tavoitteeni on lisätä lehden levikkiä sekä julkaisumäärää. Tällä hetkellä lehti ilmestyy vain kaksi kertaa vuodessa, minkä toivoisin tuplaantuvan tulevina vuosina. Hieman pienemmät visiot liittyvät pääasiassa lehden sisältöosuuksiin. Haluaisin muun muassa lisätä lehteen osion, jossa kuultaisiin alan professoreiden mielipiteitä ajankohtaisista asioista. Tällainen ”Proffan suusta” -palsta pyritäänkin saamaan vielä ensi syksynä julkaistavaan numeroon. Uskon että mielenkiintoisella ja ajankohtaisella sisällöllä pystymme lisäämään lehtemme lukijamäärää.”
Mitä odotat tulevilta päätoimittajavuosilta?
”Tulevaisuudelta odotan erityisesti uuden oppimista, mielenkiintoisia tekstejä sekä visioiden toteutumista. Olen jo nyt saanut tutustua lukuisaan joukkoon uusia taitavia ihmisiä, minkä toivon jatkuvan tulevaisuudessakin!”
The
Department of Anesthesiology at Washington University School of Medicine
welcomes applications for a tenure-track faculty position in The Center for Clinical Pharmacology,
a multi-institutional
research center established in partnership with with St Louis College of
Pharmacy in 2015. Successful candidates will join an existing group of
faculty with research interests in basic and translational
pharmacological science.
The goal of the Center for Clinical Pharmacology
is to focus on human-oriented research that spans the continuum of
basic to translational and clinical research, specifically through
research
that improves the use of both current and new therapeutics and
diagnostics. The Center faculty brings vast experience in
multiple aspects of drug discovery including drug mechanisms, medicinal
chemistry, PK/PD, pharmacogenomics and drug development.
The Center has a deep interest in “chemical biology”, pharmacology,
behavior and neuroscience.
This position
is targeted at established investigators at the Associate Professor or
Professor levels. Strong preference will be given to candidates
currently conducting translational and/or clinical
research. Additional leadership opportunities are available dependent
upon experience. Successful candidates will be expected to direct an
active extramurally funded research program and participate in graduate
and/or postdoctoral education, with faculty appointments
at both Washington University School of Medicine and the St Louis
College of Pharmacy. Teaching opportunities are readily available but
requirements are minimal, permitting a strong focus on research.
Generous startup funds and newly constructed lab space are
available.
Candidates
must have a doctoral degree (PharmD, PhD, MD or equivalent) and a
demonstrated record of accomplishment as an independent investigator.
Applications will be reviewed as received until the
position is filled.
To apply, send a curriculum vitae, a summary of past research activities, future research plans, and the names of three references to:
The
Department of Anesthesiology at Washington University School of Medicine
in St Louis fosters an academic culture in which clinical care,
research, and education are seamlessly integrated. The
department makes major contributions to the science of anesthesiology
through its basic science and clinical science programs, which are
heavily focused on innovative education and comprehensive, personalized
clinical training.
Founded in
1864, St. Louis College of Pharmacy is the third-oldest and
10th-largest college of pharmacy in America. The College provides
students unparalleled opportunities to learn through research,
internships, and other hands-on learning experiences with their
neighbors Barnes-Jewish Hospital, Washington University School of
Medicine, and St. Louis Children’s Hospital.
Vihdoin pääsemme ylpeänä kertomaan, mitä jäsenlehtemme toimituksessa on viime aikoina puuhailtu: Solubiologi-lehti on uudistunut täysin ilmettään ja sisältöään myöten! Kevään numerossa on luvassa mm. yhdistyksen 45-vuotisjuhlakooste, kolumni, kuukauden solubiologi ja kattava artikkeli solumekaniikan tutkimusmenetelmistä. Tätä jos mitä kannattaa odottaa, uudistunut lehti näyttää nimittäin todella hyvältä! Ennen painoon lähtöä on jäljellä enää muutama loppusilaus, joten uusi Solubiologi on pian postiluukussasi!
Harvard Medical School and Cancer Center at Beth Israel Deaconess Medical Center
Postdoctoral position(s) available on summer/autumn 2019
Our
lab studies how cancer cells develop drug resistance, and more
specifically, how tumor microenvironment provides support and protection
for tumor cells. Our aim is to develop better
treatment strategies to overcome this tumor microenvironment mediated
drug resistance.
To
investigate these topics we utilize both normal and cancer cells in 3D
organoid culture systems, which mimic the architecture and organization
of tissues. We use this platform in co-culture
systems to understand how stromal and epithelial cells communicate with
each other, and have also adopted the use of organoids for larger scale
methodologies, such as proteomics, metabolomics, RNA-seq and ribosome
foot-printing experiments to gain insight
into multiple mechanisms by which cancer cells become drug resistant in
3D environments.
Our
group is located in the Longwood medical area, at the Beth Israel
Deaconess Medical Center, with several established collaborations with
groups in the Harvard Medical School, MIT,
Yale, Weill Cornell and MD Anderson. This environment provides unique
opportunities for performing cutting-edge science, training in
state-of-the-art technologies, forming new collaborations, and
developing new technologies.
We
are looking for highly motivated individual(s) who have recently
finished (or about to finish) their PhD, with excellent communication
and critical thinking skills, and who are able
to work as part of a team. Training in cell biology, molecular biology
and microscopy, and basic understanding of cell signaling networks is
required.
Or
refer to the relevant publications: Muranen et al. Cancer Cell 2012,
Muranen at al. Cancer Research 2016, Muranen et al. Nature
Communications 2017 (http://rdcu.be/oqQ6).
Please
send a cover letter with short description of your research interests
and previous experience, current CV, and names of three references to
tmuranen@bidmc.harvard.edu.
The
research group of associate professor Dario Greco at the Faculty of
Medicine and Health Tehcnology and BioMediTech Institute at the Tampere
University
(Finland) focuses in advancing the fields of systems toxicology and
predictive pharmacology using big data modelling and machine learning
algorithms. We have a unique combination of expertise that spans systems
biology, toxicology, cheminformatics and bioinformatics.
Our vision is to push the state-of-the-art in predictive toxicology and
pharmacology and subsequently address some of the major challenges
arising in chemical safety assessment and drug development. We are
seeking for highly motivated postdoctoral researcher
and PhD student with a strong background in data mining, data
modelling, biostatistics and machine learning.
The
main tasks will include: integrating, analyzing and modelling large and
diverse datasets comprising molecular descriptors and mechanism of
action
(OMICS data) of chemicals and nanomaterials; analyzing and modelling
large OMICs data sets of molecular epidemiology; collaborating with
other researchers in Finland and abroad.
The
ideal candidates hold a M.Sc./Ph.D. in relevant disciplines with a
strong publication record. Moreover she/he is an expert in at least one
of the
following: OMICS data analysis and integration, QSAR, read-across,
statistical modelling, network inference.
Applications including
i)
a research statement,
ii)
a CV and
iii)
a cover letter including names of at least two referees,
can be sent via email to dario.greco(at)tuni.fi
by the 30th of May 2019.
GrecoLab is currently involved in the large collaborative projects:
