Doctoral Student – University of Eastern Finland, Kuopio



We are applying for a highly motivated professional to work in the Leinonen Retina Laboratory. The applicant will be working in a project that aims to solve basic mechanisms of homeostatic plasticity in the nervous system. The applicant will evaluate homeostatic plasticity and functional adaptation of the retina in response to damage to the sensory photoreceptors and subsequently the cellular mechanisms explaining the phenomenon. The research tasks include eye imaging and measurement of visual function in animal models, electrophysiological techniques, basic molecular biology assays as well as state-of-the-art bioinformatics methods such as single-cell RNA-sequencing. The project will be performed in close collaboration with the University of Utah (UofU, Salt Lake City, Utah, USA) and part of the data collection will be conducted during a research visit to UofU.

The research tasks will include:
Bioinformatics from proteomics and single-cell RNA-sequencing data
Basic molecular biology methods such as immunohistochemistry, western blotting, quantitative RT-PCR, RNA-sequencing
Vision assessment in laboratory animals: electroretinography, cortical visual evoked potentials, behavioural vision tests
Electrophysiology in isolated retinas
Drug trials in animal models

Requirements and expectations

relevant Master’s degree with a firm training in neuroscience, pharmacology, molecular biology, biomedicine or equivalent field. Experience in in vivo work will be the greatest advantage for the position.
fluent English language skills
adaptability to work both independently and as a team member
preparedness for an international research exchange (to USA)

Please apply through instructions in this link: https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=16&id=000012100&lang=fi