HDX-MS scientist – Orion Corporation, Espoo



About the job

Are you eager to set up HDX-MS at Orion and apply the technique to interesting proteins to boost our drug discovery?

Description Of Position

As HDX-MS specialist in the unit “Structural Biology and Analytics” you will be responsible to set up the technique, promote it in project teams and boost the understanding of protein ligand interactions and folding of proteins.

Location: Espoo

Temporary position for 3 years

Description Of Unit

The unit as part of the Medicine Design has the task to purify and analyse small molecules, to characterize their physico chemical properties, to determine binding parameter to proteins and other biomolecules and to study ligand/protein interaction to elucidate binding sites and structures via NMR, MS, and chromatographic techniques. In addition, it coordinates structural analysis via X-ray or cryoEM with external partners.

We offer

The position offers exciting and challenging opportunity for cross-scientific and -cultural collaboration and working in highly motivated teams. You will have the chance to build up HDX-MS as an extension to our AS-MS and native MS capabilities. We have a good working atmosphere based on common values and mutual trust. Take a look at our values!


Solid knowledge in protein-MS and especially HDX-MS is needed to support our activities in characterisation of protein-ligand interaction or to analyse conformational changes of proteins. The candidate needs to have a good knowledge in protein handling and must be able to discuss in multidisciplinary project teams results and impact of the results on drug design. Basic understanding on biophysical methods is beneficial. A good network to the HDX-MS community around the world are a big plus.

Additional Information

Please send your application incl. salary request and CV by the 26 June 2023. We will start reviewing applications during the application period.

For additional details, please contact Head of Structural Biology and Analytics Josef Messinger tel. +358 50 966 5287 (Monday 29th May 10-15 o’clock Finish time and 15th June 13-15 o’clock Finish time)

Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person. Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.