Postdoctoral Researcher position, A.I. Virtanen Institute for Molecular Sciences, Kuopio Campus

Postdoctoral Researcher
The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,000 students and 2,500 members of staff. From 1 August 2018 onwards, we’ll be operating on two campuses, in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 2 500 degree students and about 450 PhD students in the Faculty. The faculty has 680 staff members. http://www.uef.fi/en/ttdk/etusivu

We are now inviting applications for 

Postdoctoral Researcher position, A.I. Virtanen Institute for Molecular Sciences, Kuopio Campus 

The position is offered by the University of Eastern Finland and relates to a project that is sponsored by a pharmaceutical company. The chosen candidate will be based in the group of Associate Professor Tarja Malm (
https://www.uef.fi/en/web/aivi/tarja-malm-group) and the project will be carried out in tight collaboration with the company.
The aim of the project is to characterize the impact of Aβ and/or Tau pathology on synaptic function and structure using electrophysiology and two-photon imaging of biopsied human brain tissue obtained from idiopathic Normal pressure hydrocephalus (iNPH) patients, some of which have concomitant Alzheimer’s pathology. Early aims will be to set up electrophysiology protocols and assays to analyze intrinsic membrane properties and understand different neuronal response properties as a function of Alzheimer’s pathology. These experiments will be complemented with functional and structural imaging of synapses using genetically-encoded fluorescent reporters using two-photon microscopy. 
A person to be appointed as a postdoctoral researcher shall hold a suitable doctoral degree. Positions of postdoctoral researchers shall always be filled for a fixed term (UEF University Regulations, Section 31). 

The person to be appointed to the Postdoctoral Researcher Position is required to hold a doctoral degree, which may not have been completed more than five years ago at the time of accepting the position. In this context, the 5 years refer to a net period of time, which does not include maternity leaves, parental leaves, or military service, etc. 

The language requirements associated with the position are defined in the Government Decree 770/2009. Members of the university’s teaching and research staff are required to have command of the language they give teaching in (Finnish or Swedish). The Dean of the faculty may grant an exemption from the language proficiency requirements laid down in the Government Decree. 
The candidate should have a PhD in Neuroscience or a related discipline with experience in analyzing functional properties of neuronal circuits. Candidates with a PhD in physics or engineering and with sufficient background in Neuroscience are also encouraged to apply. Strong and proven experience in slice electrophysiology is desired. In addition, experience in immunohistochemistry, two-photon imaging, image and data analysis is advantageous. Enthusiasm and commitment will need to be coupled to attention to detail and strong analytical skills. Good knowledge of written and spoken English is essential. An ideal candidate must have a high degree of independent thought and initiative. The applicant needs to have recommendation from two previous and recent supervisors / PIs.
You will join a very active and well-equipped group of neuroscientists studying various aspects of neuronal function, neuroinflammation in the context of different neurological diseases. You will have a direct interaction with the experts in the neuroscience behind Alzheimer’s disease and therapeutics based at the company.  
The position is filled for one year starting from 15.3.2018 or as agreed. The position is filled for a fixed term due to the duration of the project. 

The salary of the position is determined in accordance with the salary system of Finnish universities and is based on level 5 of the job requirement level chart for teaching and research staff (€2,865.30/ month). In addition to the job requirement component, the salary includes a personal performance component, which may be a maximum of 46.3% of the job requirement component. 

For further information on the position, please contact: Associate Professor Tarja Malm, tel: +358 40 3552209, tarja.malm@uef.fi. For further information on the application procedure, please contact: HR Secretary Asta Suhonen, tel. +358 40 3552000, asta.suhonen@uef.fi

A probationary period is applied to all new members of the staff. 

The electronic application should contain the following appendices: 

a résumé or CV 
a list of publications 
– copies of the applicant’s academic degree certificates/ diplomas, and copies of certificates / diplomas relating to the applicant’s language proficiency, if not indicated in the academic degree certificates/diplomas 

–  Recommendation letters from two previous and recent supervisors / PI
The application needs to be submitted no later than 25.2.2018 (by 24.00 hours Finnish time) by using the electronic application form.