Ajankohtaista

Cell culture laboratory assistant

https://www.orion.fi/en/careers/open-vacancies/

Orion Corporation operates in more than 20 countries, where we Orionees, 3200 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.

We are seeking a laboratory research assistant to join the Protein & Antibody Engineering unit.

Description of position

As research assistant you will play an important role in the unit. You will be supporting our projects and working closely together with scientists and assistants both within our own unit and cross-functionally. Your tasks will span activities from protein production to characterization, but your main focus will be on cell culture work, developing and maintaining cell lines, and producing proteins. You will have good opportunities to learn new skills and develop your competences.

Key responsibilities:

• Working closely together with the team and support projects with experimental work
• Maintain cell cultures
• Support protein production with transient transfection of mammalian and bacterial cells
• Support the team and projects with experimental work withing protein purification and characterization
• Contribute to our technology development projects
• Developing and maintaining laboratory protocols

Desciption of Unit

Protein & Antibody Engineering is a newly established unit and an integrated part of the Medicine Design department, which is responsible for converting new drug targets into large and small biomolecule therapeutics. The unit is tasked with the discovery and antibody engineering incl. novel formats for the treatment of diseases in Orion’s focus areas Oncology and Neurological disorders. We are involved in the projects form the early ideas until delivery of the clinical candidate. The laboratory has a fully equipped protein production facility and a wide range of characterization technologies. Expanding our capabilities and building technologies is essential for us and we are constantly exploring new ideas and implementing new methods, platforms, and technologies. The unit is currently composed of 9 scientists, 1 assistant as well as a handful of students and post doc researchers working with various aspects of protein production and characterization.

We offer

The position offers an exciting and challenging opportunity for being part of a small team with a big responsibility in one of Finlands most innovative companies. You will be working with highly motivated people in pharmaceutical industry on versatile projects and be part of building our protein and antibody capabilities for the future of Orion. Constant development and appreciation of personnel are part of our core values and we can offer attractive career development opportunities. The culture of Orion R&D is informal and we enjoy working together.

We strive for excellence in everything we do. We succeed, learn together, and appreciate each other. You’ll be empowered to deliver value.  Please follow this link for Orion’s values.

Requirements

To succeed in this role you need to:

• Have good hands-on experience working with cell cultures
• Have experience working in a clean cell culture laboratory
• Have hands-on experience working with protein samples
• Be a motivated team player
• Be motivated to learn and take on new challenges
• Have a positive can-do attitude
• Thrive well in an constantly changing environment

Additional information

Are you the person we are looking for? Please send your CV and application to us by July 5th at the latest.

For more information please contact Rune Salbo, Head of Protein & Antibody Engineering by phone +358 50 966 7718 via email rune.salbo@orionpharma.com.

Join us – together we build well-being and do work that we are proud of!

#LI-ORION

Approved medical examination which also includes drug testing is required prior to the employment.

Manager, Clinical Product Development

https://www.linkedin.com/jobs/view/2626227355/?refId=D5l5nyXFQWeyuxabnKAGgg%3D%3D

About the job

Are you looking to join a dynamic, innovation-driven, international company, building a better future for us all? UPM leads the forest based bioindustry into a sustainable, innovation-driven, and exciting future. The competence, integrity and drive of our people make us unique. We live by our values – trust and be trusted, achieve together, renew with courage.

We are now looking for a Manager, Clinical Product Development to join our Biomedicals team in Helsinki, Finland.

Greetings from your future team leader

“We are looking for an experienced, dynamic, open minded individual with a “can-do” attitude. You will be responsible for the wound care products, but also support the developments in regenerative medicine. Since this is a new area for UPM, you will be part of the exciting development phase!” – Johana Kuncová-Kallio, Director, UPM Biomedicals

What You’ll Do

• You will play a key role in the development of the regulatory route for our existing and upcoming products
• You act as a product manager for FibDex® advanced wound dressing, and will be responsible for product documentation maintenance and post market surveillance
• Together with the team, you will be responsible for product development including but not limited to new indications of FibDex® advanced wound dressing and other products for wound healing
• You will also support new product development for regenerative medicine and pharmaceutical products
• You will be responsible for regulatory documentation and related quality management processes and reporting
  

Who You Are

• You have a university science degree, understanding of wound healing or regenerative medicine mechanisms and a minimum 5 years of relevant work experience, ideally in industry
• A background in biomaterials is seen beneficial
• You have a deep understanding and working knowledge of ISO 13485, QC, GMP, MDR practices, document management and associated country registration requirements
• You have previous experience of medical device product development for the clinical market (strong preference on experience with regulating materials and devices over software) and experience in management of clinical trials
• Experience from internal auditing, especially medical devices audits, is also an advantage
• You have proven business acumen and working knowledge of the industry and supplier base
• You have excellent communication and problem-solving skills and are able to work independently
• You are a positively thinking, solution oriented, multitasking and proactive team player
• You are fluent in written and spoken English
  

This Is What We Offer For You

• Meaningful job: We are proud of what we do. Saving patients’ lives, developing a new area of UPM, working in a company with high values.
• Inspired and motivated teams: In the Biomedicals team, you will be working with great people. UPM is a multifaceted, international organization that works as a team to achieve our shared objectives.
• Development opportunities: We work together on advancing your career. We provide opportunities to support your development throughout every stage.
• Responsibility for people and environment: Our ethical principles embrace people as well as the environment. We are always striving to build a more sustainable future.
  

Additional Information

The main location for this position is Biomedicum 2U, Tukholmankatu 8, Helsinki. Other locations, where you will work time-to-time, include the headquarters of UPM at Alvar Aallon katu 1, Helsinki and the North European Research Center in Lappeenranta.

For further information about the position, please contact your future manager Kaija Ojala, Business Development Manager, Clinical tel. +358400883440, on Tuesday 29.6.2021 at 9-12 (EET), or Wednesday 30.6.2021 at 11-14 (EET) or your future colleague Kari Luukko, Director, Quality Assurance, tel. +358400259866, on Tuesday 22.6.2021 at 12-15 (EET) or Wednesday 23.6. at 13-16 (EET).

Please send your application via the link by 15.7.2021. We will start going through the applications already during the application period, so please submit your application as soon as possible.

For support with submitting your application, please contact the HR Service Center at careers@upm.com or tel. +358204146600. If you are a UPM employee you can reach us through the UPM Service Portal: [LINK].

A security background check may be performed for those selected to UPM positions, in accordance with the company recruitment guidelines and the Security Clearance Act 726/2014.

UPM is a non-smoking workplace in Finland.

UPM Biomedicals is the forerunner in producing high quality nanofibrillar cellulose for medical and life science applications. More than 300 patents protect the existing and future products that rely on the Finnish birch pulp. We actively collaborate with universities, research centres and key industrial partners on innovations and products in the field of high throughput drug screening, personalized medicine, advanced cell therapies, 3D bioprinting, tissue engineering and wound care. www.upmbiomedicals.com

We deliver renewable and responsible solutions and innovate for a future beyond fossils across six business areas: UPM Biorefining, UPM Energy, UPM Raflatac, UPM Specialty Papers, UPM Communication Papers and UPM Plywood. As the industry leader in responsibility we are committed to the UN Business Ambition for 1.5°C and the science-based targets to mitigate climate change. We employ 18,000 people worldwide and our annual sales are approximately EUR 8.6 billion. Our shares are listed on Nasdaq Helsinki Ltd. UPM Biofore – Beyond fossils. www.upm.com

Follow UPM on Twitter | LinkedIn | Facebook | YouTube | Instagram | #UPM #biofore #beyondfossils

Industry

• Biotechnology
• Packaging & Containers
• Paper & Forest Products

Employment Type

• Full-time

Job Functions

• Health Care Provider

Vuorotteluvapaan sijaiseksi Immunoon

https://www.immunodiagnostic.fi/vuorotteluvapaan-sijaiseksi-immunoon/

Meillä on syksyllä tarvetta sinulle, joka olet innostunut laittamaan jalkasi oven väliin, kun rakennat tulevaisuuden työuraasi.

Sinulla on Immuno Diagnostic Oy:n liiketoimintaa ajatellen sopiva tausta esim. kliinisen mikrobiologian, elintarvikekemian, molekyylibiologian tai biokemian alueelta. Sopivan taustan lisäksi sijaisuus edellyttää hyviä vuorovaikutus- ja yhteistyötaitoja, itsenäistä työotetta sekä innokkuutta ottaa vastaan uusia haasteita.

Hakijan tulee täyttää vuorotteluvapaan sijaiselle asetetut TE-keskuksen kriteerit. Tarjoamme sinulle hyvän perehdytyksen, modernit työkalut sekä mahdollisuuden oppia uutta. Mikäli tarpeemme sopii syksyn suunnitelmiisi, lähetä vapaamuotoinen hakemuksesi ja CV:si osoitteeseen rekry@immunodiagnostic.fi. Lisätietoja antaa toimitusjohtajamme Tomi Virtanen (puh. +358-40 501 2055), kysymyksiä voi esittää myös rekry-sähköpostiin.

Otathan yhteyttä

Tomi Virtanen

Toimitusjohtaja tomi.virtanen@immunodiagnostic.fi

Erityisasiantuntija, mikrobiologia, Työterveyslaitos

https://tyopaikat.oikotie.fi/avoimet-tyopaikat/erityisasiantuntija-mikrobiologia/1468310

Haemme Työympäristölaboratoriot-yksikköön Kuopion toimipisteeseen

ERITYISASIANTUNTIJAA  

Työterveyslaitos tarjoaa laajan valikoiman tutkittuun tietoon perustuvia työympäristön analyysipalveluita, puolueetonta neuvontaa ja moniammatillisia ratkaisuja.  Työterveyslaitoksen laboratoriotoiminta on FINAS-akkreditointipalvelun akkreditoima testauslaboratorio T013 (SFS-EN ISO/IEC 17025:2017) ja laboratoriollamme on myös Ruokaviraston hyväksyntä asumisterveyteen liittyvissä määrityksissä. 

Tehtävänäsi on tuottaa akkreditoidussa laboratoriossa laadukkaita mikrobiologian sekä pöly- ja kuituanalytiikan laboratoriopalveluita sisäisille ja ulkoisille asiakkaille. Tehtävänäsi on analysoida palvelunäytteitä, tunnistaa mikrobeja näytteistä, osallistua asiakkaiden konsultointiin ja kehittää menetelmiä. Lisäksi tehtävä sisältää akkreditoidun toiminnan kehittämistä ja ylläpitämistä.

Odotamme sinulta ylempää korkeakoulututkintoa sekä monipuolista perehtyneisyyttä sisäympäristön analytiikkaan. Arvostamme mikrobiologin, biologin tai vastaavaa koulutusta, sekä aiempaa kokemusta mikrobien tunnistamisesta, asbestianalytiikasta, kokemusta akkreditoidun toiminnan ja analytiikan kehittämisestä ja palvelutyöstä. Työ edellyttää erinomaista suomen kielen taitoa, oma-aloitteista asennetta, hyviä vuorovaikutustaitoja sekä yhteistyökykyä.

Tarjoamme sinulle monipuolisen ja haastavan työn sekä hyvät mahdollisuudet kehittää omaa osaamista. Käytössäsi ovat kattavat työsuhde-edut, joihin kuuluvat mm. laaja työterveyshuolto, liikunta- ja kulttuurietu sekä mahdollisuus käyttää tunti työaikaa viikossa liikuntaan. 

Työsuhteesi on vakituinen ja alkaa 1.9.2021 tai sopimuksen mukaan. Palkkaus määräytyy Työterveyslaitoksen työehtosopimuksen mukaan. Noudatamme kuuden kuukauden koeaikaa.

Kiinnostuitko? Täytä hakemuksesi ansioluetteloliitteineen viimeistään 20.8.2021, osoitteessa www.ttl.fi/rekry. Aiemmat hakemukset aikavälillä 4.5.–6.6.2021 vapaana olleeseen erityisasiantuntijan tehtävään Kuopiossa huomioidaan.

Lisätietoja tehtävästä antavat johtaja Sirpa Pennanen, puh. 030 474 7234 sekä tuotepäällikkö Maija Kirsi, puh. 030 474 7024 tai sähköpostitse etunimi.sukunimi@ttl.fi.

Doctoral student, the Faculty of Biochemistry and Molecular Medicine

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=1&id=000011601&lang=fi

We are now looking for a motivated Doctoral student in a project addressing the roles and molecular interactions of collagen XIII (ColXIII) in the neuromuscular junction (NMJ).

Description

Applications are invited for a full-time Doctoral student (max. 4 years) position, starting at the earliest on 1.10.2021 in a research project headed by Professor Taina Pihlajaniemi in the Extracellular matrix & Hypoxia Research Unit, operating at the Faculty of Biochemistry and Molecular Medicine. Molecular and environmental basis for lifelong health is one of the strategic focus areas of the University.  The doctoral student is enrolled in the Health and Bioscience Doctoral Programme of the University of Oulu Graduate school, which provides support in theoretical and practical training.

We are now looking for a motivated Doctoral student in a project addressing the roles and molecular interactions of collagen XIII (ColXIII) in the neuromuscular junction (NMJ). Using murine models we have shown that ColXIII is an essential NMJ component and others have recently shown that mutations in the human gene cause congenital myasthenic syndrome type 19 (CMS19). Using mouse and cell culture models we will identify the network of molecules and the events whereby ColXIII operates in the normal NMJ and the developmental events that lead to CMS19. We will also determine the occurrence of anti-ColXIII autoimmune antibodies in patients with acquired generalized and ocular myasthenia gravis and assess their effects on the NMJ. The studies provide unique opportunities to enhance the understanding of critical motor synapse molecules and facilitate personalized therapies in genetic and acquired myasthenia. The position is fixed-term for 4 years in an Academy of Finland-funded project and it targets to completion of a Doctoral thesis and multiple publications in high-ranked international journals. Besides research, the position includes some teaching duties in an international Master’s Programme in Biochemistry.

Qualification requirements

The successful candidate for the Doctoral student position must possess a M.Sc. degree in the field of biochemistry, molecular or cell biology, medical science or related fields. We also invite applications from pre-graduate students from these fields of university studies. In this case, to be eligible for application, the candidate must demonstrate that he/she will graduate at home University not later than 31.12.2021 and also provide 1) an official statement from the home University attesting that all the courses, exams and other qualifications needed for graduation have already been obtained, 2) an official statement from the home University attesting that thesis has been submitted for evaluation and, 3) a letter of support from the candidate’s Supervisor (the minimum acceptable level for supervision is docent / assistant professor).

Prior experience in molecular biology and cell culture-based experiments is required, and proficiency in microscopy is expected. Prior experience in generating or working with experimental mouse models, and knowledge of the research field in question is considered an advantage. Good communication and teamwork skills are appreciated. Fluency in both written and spoken English is required. Most importantly, we expect the candidate to have a high motivation to conduct high-level biomedical research.

What we offer

We offer a research environment with excellent technological facilities and a motivating and supporting international community at the Faculty of Biochemistry and Molecular Medicine, University of Oulu. We can also offer access to state-of-the-art facilities and special expertise through visits to collaborative laboratories outside Oulu when needed. You will have a place in a highly talented research group, working to solve globally significant research problems. University´s wide variety of support services are at disposal, allowing to focus on studies and research work. The position is fixed-term for 4 years as of 1.10.2021 or as soon as possible thereafter. A trial period of 6 months is applied in the position.

Salary

The initial salary for the new Doctoral student will be based on the demand level 2 of the national salary scale for teaching and research personnel of Finnish universities.  In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component) and upgraded based on qualification in research work and progress in PhD studies. In practice, the salary of a new doctoral student will be roughly 2300-2500 € / month before taxes. The salary will be evaluated yearly.

How to apply

Applications, together with all relevant enclosures, must be submitted using the electronic application form by August 15, 2021, at 23:59 (Finnish local time, EEST), with the following attachments as three separate pdf files:

1. Complete CV containing contact information of at least two referees (Max. size limit of the attachment: 5 Mbytes)

2. Motivation letter summarizing professional experience and expertise, reasoning interest in this position and describing career plans (1-2 pages; max. size limit of the attachment: 2 Mbytes).

3. Certificates/Diplomas: Scanned electronic copies of diplomas and transcripts of the records of relevant previous degrees. For the candidates who do not yet hold the M.Sc. degree, please provide: 1) an official statement from the home University attesting that the coming graduation date of the candidate is 31.12.2021 at the latest; 2) an official statement from the home University attesting that all the courses, exams and other qualifications needed for graduation have already been obtained; 3) an official statement from the home University attesting that thesis has been submitted for evaluation and, 4) a letter of support from the candidate’s Supervisor (the minimum acceptable level for supervision is docent / assistant professor). (Max. size limit of the attachment: 2 Mbytes)

Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Top candidates will be invited to an on-site or remote interview. Applications sent by email will not be considered. The eligible applicants fitting best in the research profile expected for the position may be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.

Further information

For further information, please contact Prof. Taina Pihlajaniemi, e-mail: taina.pihlajaniemi (at) oulu.fi or Dr. Anne Heikkinen; e-mail: anne.heikkinen (at) oulu.fi

Postdoctoral Researcher, Population Genomics

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=1&id=000011533&lang=fi

A three-year Postdoctoral Researcher position in Population Genomics is available in the Ant Genomics and Immunity group (https://lumiviljakainen.wordpress.com/).

In this project, funded by the Academy of Finland, we will study genetic underpinnings of convergent evolution of multi-queen colonies (polygyny) in ants. We will investigate genomic architecture and selection across the genomes of monogynous and polygynous ant species using whole-genome sequencing. In addition, immune gene evolution will be studied in these ant societies to decipher whether polygynous lineages have followed similar evolutionary trajectories after convergent evolution.

Open position

• the main duties of the successful candidate are bioinformatics and population genomic analysis of whole-genome sequence data of several ant species and dissemination of research findings
• other tasks include supervision of Ph.D. and M.Sc. students

Qualification requirements:

• Ph.D. in biology, obtained less than 10 years ago
• Experience in population genetics, high-throughput sequence data and bioinformatics
• Ability to work both independently and in a team, and supervise graduate and undergraduate students
• Fluency in both written and spoken English

 What we offer

• We offer you a place in an ambitious research group with excellent international collaborators
• University´s wide variety of support services are at your disposal, allowing you to focus on your research
• In addition to modern research facilities, we offer you personnel benefits such as free occupational healthcare, affordable sport services and endless opportunities to develop your skills and competences
• Regular salary is paid 12 months per year, including paid leave and an additional holiday bonus in the summer
• The successful candidate will also receive benefits provided by the Finnish government to residents, for example possibility to obtain access to the national healthcare system, tax benefits for employees with children and high-quality, affordable childcare services.

Salary

A salary in accordance with the Finnish universities salary system (for teaching and research personnel): level 5. In addition, a salary component based on personal work performance will be paid (maximum of 50% of the job-specific component). Starting gross salary will be approx. 3500€ per month. A trial period of six months is applied in the position.

How to apply

Applications, together with all relevant enclosures, should be submitted using the electronic application form by 30^th of June 2021. The application should be written in English and include the following:

1)     A motivation letter (max. 2 pages) summarizing applicant’s professional experience and expertise and describing why applicant is interested in this position. Also, information on personal research interests, experience and career plan may be provided here

2)     Curriculum vitae (max. 4 pages)

3)     List of publications based on the guidelines of the Academy of Finland: https://www.aka.fi/en/research-funding/apply-for-funding/how-to-apply-for-funding/az-index-of-application-guidelines2/list-of-publications/

4)     Certificates/Diplomas: Scanned copy of the original doctoral degree certificate and transcript of records and, when necessary, official translations to Finnish or English

5)     Contact information of two senior/experienced researchers who may be asked to give a statement on the candidate

Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Top candidates will be invited to an on-site or remote interview.

Further information

The position is for 3 years starting in September 2021 or as soon as possible thereafter. A trial period of 6 months is applied in the position.

Please contact Dr. Lumi Viljakainen (lumi.viljakainen@oulu.fi) with any questions.

Quality Control (QC) Lab Technician

https://www.recright.com/careers/en/nanoform-finland-oyj/quality-control-qc-lab-technician-60c3483736c0fe5b898dee96

About Nanoform   

Nanoform is an innovative drug particle engineering and nanotechnology company listed on the Premier-segment of Nasdaq First North Growth Market in Helsinki and Stockholm. Nanoform works together with pharma and biotech partners globally to reduce attrition in clinical trials and enhance their molecules’ formulation performance through its nanoforming services. Leveraging our in-house developed AI engine Starmap® we can also predict which customer molecules show most promise for our technology. Nanoform’s capabilities include GMP manufacturing, and its services span the small to large molecule development space with a focus on solving key issues in drug solubility and bioavailability and on enabling novel drug delivery applications.     

Quality Control (QC) Lab Technician  

With the view of developing our organization further, we are now seeking Quality Control Lab Technician to support our quality control team. The position requires availability to integrate shift work regime. The job is located at our facilities in Helsinki, Finland.   

You will be responsible for    

• Ensure that all QC analysis are carried out in an effective and accurate manner according to company standard procedures (SOPs). 
• Implement and develop new methods.
• Maintain and calibrate laboratory equipment.
• Manage reagent, material, and standards stock levels to ensure lab work continuity.
• Ensure that records are done in an accurate manner as per company standards and procedures.
• Support the GMP laboratory activities as per company standard procedures and Quality system. 
• Support current R&D projects by running appropriate analysis and sampling.
• Maintain QC Databases and others relevant for QC operations
• Communicate efficiently with the production and technical teams to discuss QC outcomes and improvements

Ideal experience     

• You have a Bsc or Msc degree in pharmacy, chemistry, microbiology, biotechnology or in an equivalent field. 
• You have been working with biomolecules (especially with proteins).
• Experience from some of the analytical techniques: SDS-PAGE, HPLC-(SEC), immunoassays, DLS.
• Working knowledge of SOPs, Pharmacopeias and GXP Regulations.
• Good technical knowledge and understanding of laboratory procedures, methodology and standards.
• Capacity to work independently in a laboratory environment 
• Capacity to produce clear records and data reports.
• Experience in working in GXP environments. 
• Preferred experience in using electronic Quality systems (LIMS, QMS, CDS, CAPA, others).  
• You are used to work with MS Office programs.

Personal qualities we are looking for 

• You are a doer and have an accurate working style 
• You are flexible in working in a team as well as independently 
• You have an ability to work in a high-performance environment 
• Good English level, both written and spoken   

What we offer to you  

• A great team to join with skilled and highly motivated colleagues
• Encouraging and forward-looking team spirit
• You will be part of a team that invents world-class solutions for the pharmaceutical industry
• We provide extensive learning opportunities. You are able to utilize your skills and competencies widely as we continuously create something new
• We like challenges and want everyone to enjoy solving them together
• Competitive compensation package with broad employee benefits selection

You will get to be part of a unique start-up in the pharma industry.   

Interested?   

To apply for this position, please supply a covering letter and CV by 21st of June, 2021. Please note that we may already start the interviewing process during application period.   

Quality Control Lab Technician

https://www.recright.com/careers/en/nanoform-finland-oyj/quality-control-lab-technician-60c35a7336c0fea0d68df604

About Nanoform 

Nanoform is an innovative drug particle engineering and nanotechnology company listed on the Premier-segment of Nasdaq First North Growth Market in Helsinki and Stockholm. Nanoform works together with pharma and biotech partners globally to reduce attrition in clinical trials and enhance their molecules’ formulation performance through its nanoforming services. Leveraging our in-house developed AI engine Starmap® we can also predict which customer molecules show most promise for our technology. Nanoform’s capabilities include GMP manufacturing, and its services span the small to large molecule development space with a focus on solving key issues in drug solubility and bioavailability and on enabling novel drug delivery applications.   

Quality Control (QC) Lab Technician  

With the view of developing our organization further, we are now seeking Quality Control Lab Technician to support our quality control team. The position requires availability to integrate shift work regime. The job is located at our facilities in Helsinki, Finland.   

 You will be responsible for    

• Ensure that all QC analysis are carried out in an effective and accurate manner according to company standard procedures (SOPs). 
• Implement and develop new methods.
• Maintain and calibrate laboratory equipment.
• Manage reagent, material, and standards stock levels to ensure lab work  continuity.
• Ensure that records are done in an accurate manner as per company standards and procedures.
• Support the GMP laboratory activities as per company standard procedures and Quality system. 
• Support current R&D projects by running appropriate analysis and sampling.
• Maintain QC Databases and others relevant for QC operations
• Communicate efficiently with the production and technical teams to discuss QC outcomes and improvements 

Ideal experience     

• You have a Bsc or Msc degree in pharmacy, chemistry, microbiology, biotechnology or in an equivalent field. 
• Working knowledge of SOPs, Pharmacopeias and GXP Regulations.
• Good technical knowledge and understanding of laboratory procedures, methodology and standards.
• Experience in all or some of the following analytical techniques: HPLC, UPLC, DSC, XRPD, Laser Diffraction, DLS, Karl Fisher, FTIR, SEM, AFM.
• Capacity to work independently in a laboratory environment 
• Capacity to produce clear records and data reports.
• Experience in working in GXP environments. 
• Preferred experience in using electronic Quality systems (LIMS, QMS, CDS, CAPA, others).  
• You are used to work with MS Office programs.

Personal qualities we are looking for 

• You are a doer and have an accurate working style 
• You are flexible in working in a team as well as independently 
• You have an ability to work in a high-performance environment 
• Good English level, both written and spoken   

What we offer to you  

• A great team to join with skilled and highly motivated colleagues
• Encouraging and forward-looking team spirit
• You will be part of a team that invents world-class solutions for the pharmaceutical industry
• We provide extensive learning opportunities. You are able to utilize your skills and competencies widely as we continuously create something new
• We like challenges and want everyone to enjoy solving them together
• Competitive compensation package with broad employee benefits selection

You will get to be part of a unique start-up in the pharma industry.     

We are looking forward to hear from you!

To apply for this position, please supply a covering letter by 21st of June,2021.

Please note that we may already start the interviewing process during application period.   

Early Stage Researcher, Molecular Biology

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=16&id=000011543&lang=fi

The University of Eastern Finland is inviting applications for an Early Stage Researcher in Molecular Biology – position in Joensuu campus. The position will be filled for a period of four year starting from September 1, 2021. Please find more information below and submit your application no later than 3 August 2021. 

Role and salary

The research project, funded by the Academy of Finland, aims to understand the processing of stalled mitochondrial DNA (mtDNA) replication forks, their relation to mtDNA integrity and cellular signalling responses. The PhD student will investigate the role of two proteins in the cleavage of stalled mitochondrial replication forks, the fate of broken mtDNA in cells and the signalling pathways that react to mtDNA damage or interact with extramitochondrial mtDNA.

Positions of Early Stage Researchers shall always be filled for a fixed term (UEF University Regulations, Section 31). The position will be filled for a period of four year starting from September 1, 2021. A probationary period is applied to all new members of the staff.

The salary of the position is based on the salary system for the teaching and research staff at universities. The salary consists of the job-related salary element and the personal performance salary element. For this position, the job requirement level used to determine the job-related salary element is 2–4, and the personal performance salary element is 6–50% of the job-related salary element. The estimated monthly salary in the beginning of the employment will be 2,288.17- 3,163.95 €/per month. The salary of an early stage researcher depends on the phase of the doctoral dissertation and postgraduate studies as well as personal performance.

As Early Stage researcher your main responsibilities will include:

• Manipulation of enzymes involved in mtDNA maintenance using siRNA knockdown, CRISPR/Cas9-knockout and induced overexpression in cultured cells
• Analysis of mtDNA replication intermediates and stalled replication forks using agarose electrophoresis and transmission electron microscopy
• Investigation of the signalling pathways affected by mtDNA damage or mtDNA escape from mitochondria by Western blots, inhibitors and knockdown of key components
• Research visits to collaboration laboratories
• Presenting of research results in international conferences and publishing results
• Writing of a Ph.D. thesis

Our requirements and expectations

A person to be appointed as an Early Stage Researcher shall be qualified to pursue postgraduate studies, i.e. he or she is required to have completed a suitable higher university degree or an equivalent education abroad, which in the country in question would qualify the person for similar academic studies. A master’s degree or equivalent in molecular biology, cell biology, biochemistry or a related field is required for the position. Persons graduating in the near future are also encouraged to apply. However, they are expected to hold a relevant M.Sc. degree (or equivalent) by the starting date of the Early Stage Researcher position.

Potential candidate should have good command of the English language. We expect the student to have good prior knowledge of molecular biology methods and cell culture. Previous experience with mitochondria or mitochondrial DNA metabolism is a plus.

Your benefits
You will have access to the university’s staff benefits, including

• extensive occupational health care
• staff discount on lunch in our campus restaurants, as well as on a range of other services
• affordable sports services. 

Please read more in the Work at UEF section on our website.

You will have an opportunity to work in an interesting role as part of our international, creative, participatory and inclusive academic community.

How to apply?

Submit your application by using our electronic application form no later than 3 August 2021 (by 24.00 hours Finnish time). 

Please note that you must include the following appendices in your application:

• CV (max 2 pages http://www.tenk.fi/en/template-researchers-curriculum-vitae including possible publications)
• a motivational letter and the contact details for one or two references
• copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas 

Questions?

For further information on the position, please contact Senior Researcher Jaakko Pohjoismäki, Ph.D., tel. +358 29 445 3052, jaakko.pohjoismaki@uef.fi.

For further information on the application procedure, please contact Executive Assistant Satu Turunen, tel. +358 29 445 3031, satu.turunen@uef.fi (on vacation July 3- July 30). 

Post-doc­to­ral re­searc­hers and/​or PhD-stu­dents in cell bio­lo­gy and stem cell bio­lo­gy

https://www2.helsinki.fi/fi/avoimet-tyopaikat/post-doctoral-researchers-andor-phd-students-in-cell-biology-and-stem-cell-biology

The HiLIFE – Institute of Biotechnology (BI), located in the Viikki science park, is a research institute at University of Helsinki. The institute harbors ~35 research groups and 250 researchers, and it operates at the highest international level. For more information on the Institute, please visit https://www.helsinki.fi/en/hilife-institute-of-biotechnology.

The laboratory of Dr. Jette Lengefeld is inviting applications for post-doctoral researchers and/or PhD-students in cell biology and stem cell biology.

The failure to regenerate tissue with age is a major health issue. A contributor to this decline is the loss of stem cell function. Despite the essential role of stem cells, it is still unclear how they fail to maintain their functions during ageing and disease. We discovered a new aspect of stem cell ageing in vivo: cellular enlargement. With age and damage, stem cells increase in size causing their functional decline. However, we are only beginning to understand how size impacts stem cell fitness and the physiological importance of this process remains unsolved.

The Lengefeld research group uses blood (hematopoietic) stem cells from mice and human bone marrow donations to address these fascinating questions:

• What pathways cause stem cell dysfunction during their enlargement?
  We use blood (hematopoietic) stem cells of mouse models to identify the molecular mechanisms impairing fitness of large stem cells from a metabolic perspective.
• Can we rejuvenate stem cells after aging and damage?
  We explore approaches to rejuvenate stem cells and investigate the effects on cellular ageing and organismal health.
• Does deregulation of size lead to cancer?
  We utilize blood stem cells from mice and humans to identify factors that facilitate leukaemia in vivo and to investigate the underlying mechanisms.

The post-doctoral applicants should hold PhD in cell biology, stem cell biology, cell size regulation or a related field. Strong expertise in stem cell biology and experience working with mice is highly beneficial. The PhD-student applicants should obtain MSc or related degree in the biology field latest by August 2022, and have a strong interest to carry out cutting-edge research. The positions will provide multiple opportunities for collaborations with potential lab visits abroad. An attitude to drive own research and work in an intra and inter team fashion is highly appreciated. In return, the candidates are offered an access to a wide variety of methodologies and advanced techniques. The working language of the laboratory, the BI and HiLIFE is English and good communication skills in English are required.

The postdoctoral researcher and PhD-student positions are initially limited to 2 and 4 years, respectively, with a possibility of extension. A trial period of 6 months will be applied, and the salaries will be based on the University salary scheme for teaching and research personnel composed of both task specific and personal performance components.

Application should include the following documents as a single pdf file: CV, list of publications, motivation letter including a description of your research interests, and the names and telephone numbers of at least two referees.

Please submit your application, together with the required attachments, through the University of Helsinki electronic recruitment system by clicking the “Apply for the position” – link below. Applicants employed by the University of Helsinki must submit their application through the SAP HR portal.

The deadline for the applications is 8th of July 2021, but the positions will be filled immediately once suitable candidates have been identified.

For informal inquiries, contact ‘jette.lengefeld(at)helsinki.fi’, and for more information about our research, please visit https://www2.helsinki.fi/en/hilife-institute-of-biotechnology/research/c…

For technical support regarding the recruitment system, please contact rekrytointi@helsinki.fi.