Senior Scientist, Immuno-Oncology – Orion Corporation, Turku
19.8.2023https://www.linkedin.com/jobs/view/3690195920
About the job
Description Of Position
Orion’s Immuno-Oncology (IO) research team is looking to recruit an enthusiastic and motivated in vitro senior scientist to join the IO team in Turku, Finland, on permanent basis. In this role you will contribute to IO target identification and validation, coupled with being responsible for supporting IO drug discovery projects. In this role you have a unique opportunity to contribute in a range of treatment modalities ranging from small molecules, large molecules (bispecific & monospecific antibodies) and CAR T cells.
The responsibilities of this role include the following (including, but not limited to);
- Design and perform in vitro immune assays and treatment with oncology drugs in conjunction with internal project teams.
- Establish and validate human and mouse in vitro primary immune cells assays to define the mechanism of action of IO drugs.
- Provide Immunology expert guidance and leadership to the project team as to the development of pharmacology strategy for IO drug discovery projects.
- Provide expert knowledge of tumour biology and tumour immunology to the organisation.
- Co-ordinate with the line-manager and project team to ensure timely delivery of data, and report if any issues encountered or foreseen.
- Be responsible person for CRO and external partnered studies.
- Develop and implement novel primary immune cells assay to improve the target confidence and in vitro pharmacology data package.
- Provide clear reports and presentations as required and participate in project team meetings and organisation meetings.
- Liaise with members from other organisation to establish potential biomarkers identification strategies.
- Establish role as in vitro project lead within the organisation.
- Working in close collaboration with other scientists and technicians.
Description Of Unit
Immuno-Oncology (IO) is one of the three Research teams in Orion’s Oncology R&D. IO team is accountable for novel drug discovery projects, identification of unmet need, identification & experimental validation of potential IO drug targets within state-of-the-art laboratories and technologies.
We Offer
We offer you the opportunity to show your talent in one of the most innovative companies in Finland. You get a chance to work in a challenging field of work with excellent colleagues. You will also have the chance to do meaningful work and build the future of Orion. We are striving for excellence in everything we do. We succeed, learn together and appreciate each other. You’ll be empowered to deliver value. Read more about our values!
Requirements
To be successful ideally you should have the following educational and professional work experiences:
- PhD degree in Immunology, Immuno oncology or related field with 3+ years of Industry or academic experience.
- Strong and deep knowledge in Immuno oncology, cancer immunotherapy, immune cell signalling as evidenced by high impact journal publication or poster presentation.
- Previous experience working in pharma or biotech is a plus.
- Strong in vitro research experience using primary immune cells assays is a must
- Demonstrate ability to independently design, conduct and interpret the data from complex in vitro immune cell assays.
- Demonstrate proficiency in isolation of immune cells and processing samples for multi-colour flow cytometry, multiplex ELISA, IHC, single cell RNA sequencing and gene expression analysis.
- Competency in using graph pad prism, flowjo, nSolver software and other standard office software.
- Excellent attention to details with strong communication skills.
- Flexibility and willingness to learn new techniques and take additional responsibilities as a member of the research team.
Additional Information
Please send your application in English by 10 September 2023 at the latest.
For further information, please contact Dr Anil Thotakura, Head of Immuno-Oncology, +358 50 966 7229. Best time to contact: 23rd August Wednesday 15:30 to 16:30, 30th August Wednesday 15:30 to 16:30 and 6th September Wednesday 15:30 to 16:30.
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person. Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.