Suomen Solubiologit ry

Te?ted Oy palkittiin NOME-verkoston kansainvälisessä pitchauskilpailussa

1.11.2018 | Ajankohtaista

https://turkubusinessregion.com/suomalaisyritys-palkittiin-nome-verkoston-kansainvalisessa-pitchauskilpailussa/?fbclid=IwAR07bQ-wmeBATJ4tJnZxlE3LTW3TvG_ytuD_gmmli-RB_hBtvGc5EnyQkhQ

Onnea Te?ted Oy, Leona Gilbert ja tiimi NOME-verkoston pitchauskilpailun voitosta! Muistattehan, että Leona on tulossa Rohkeat Biologit -seminaariimme jakamaan omia ajatuksiaan ja kokemuksiaan bioalalla työskentelystä tiistaina 6.11.! Leona jos joku on oikea ihminen kertomaan innovatiivisuudesta ja rohkeudesta sekä siitä, miten näitä pystyy hyödyntämään omalla urapolullaan. Tervetuloa inspiroitumaan, nähdään Ambiotican YAA303-salissa 6.11. klo 14! Ilmoittaudu mukaan laittamalla sähköpostia osoitteeseen suomensolubiologit@gmail.com tai Korpissa, mikäli olet Jyväskylän yliopiston opiskelija.

Study Director In Vivo – Charles River Laboratories, Kuopio, FI

1.11.2018 | Ajankohtaista

Study Director In Vivo – Charles River Laboratories, Kuopio, FI

Job description

For nearly 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

STUDY DIRECTOR IN VIVO

We are looking for scientist with proven track of experience in in vivo neuroscience to join Charles River Discovery Research Service site located in Kuopio, Finland.The position require an expertise in in vivo pharmacological studies in CNS area that enable to discuss and conclude in vivo data from efficacy studies in injury triggered animal models CNS diseases for example ischemia models, TBI, SCI, etc.

In this position you are responsible to lead Client projects in CNS drug discovery field. The Study Director will ensure the scientific excellence of study design, execution, data analysis and reporting. The Study Director will lead execution of the projects working closely with the team. The responsibilities of this position include communication with the Clients in all phases of the projects. The position require an expertise in in vivo animal models of CNS diseases, as well as capabilities to set up and develop new techniques and models in R&D projects. The Study Director will provide scientific input and assist in preparation of marketing materials.

Qualifications

- Higher education degree in biological science (MSc, MD), preferably PhD degree
- At least 2-3 years of experience with CNS in vivo work, including proven track of independent project execution and project management
- Knowledge and practical experience in conducting studies in animal models of ischemia and/or traumatic brain injury and/or spinal cord injury is required, conducting efficacy studies experience will be an asset
- Understanding and practical experience with in vivo pharmacology studies in CNS area including both genetically modified animal models and surgically/chemically induced models and related behavioral assays
- Understanding of scientific studies experimental design, underlining scientific principles, and ability to analyze data and interpret results
- Ability to quickly adapt to challenging research environment and to effectively utilize knowledge and experience in various scientific projects
- Fluent English oral and written, scientific writing ability, excellent communication skills, interpersonal, and teamwork abilities
- Good problemsolving skills, ability to coordinate and prioritize
- Pharmaceutical industry, Preclinical Contract Research Organization or academic post-doctoral experience will be an asset
- Proven track of people management, ability to mentor and train staff will be as asset

About Discovery

Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~70% of the drugs approved by the FDA in 2016.

For more information, please visit www.criver.com.

Muistakaahan ilmoittautua Rohkeat Biologit -seminaariimme!

30.10.2018 | Ajankohtaista

Vielä kerkeää mukaan Rohkeat Biologit -seminaariin, joka järjestetään Jyväskylässä tiistaina 6.11.! Loistava tilaisuus kuulla alamme yrittäjyydestä ja ylipäätään siitä, miten intohimostaan voi räätälöidä itselleen työn. Tule verkostoitumaan alan opiskelijoiden, työnantajien ja Suomen Solubiologit ry:n hallituslaisten kanssa rennosti viinin ja pienen purtavan parissa! Ilmoittaudu mukaan laittamalla sähköpostia osoitteeseen suomensolubiologit@gmail.com tai Korpissa, mikäli olet Jyväskylän yliopiston opiskelija.

Several postdoctoral positions are available in cell / developmental / vascular biology in the group of Taija Mäkinen at Uppsala University

29.10.2018 | Ajankohtaista

Post docs in cell / developmental / vascular biology

Several postdoctoral positions are available in the group of Taija Mäkinen at Uppsala University. The lab studies fundamental mechanisms of tissue morphogenesis in the vascular system. The aim is to understand how endothelial cells communicate with each other and the tissue environment to co-ordinate vascular morphogenesis and formation of functionally specialized blood and lymphatic vessel types. To do so, the group utilises advanced mouse genetic tools and state-of-the-art cell and molecular biology techniques (including single cell RNA sequencing, flow cytometry, confocal, light-sheet and super-resolution microscopy). For more details about the group’s research please see: http://www.makinenlab.com/

Selected recent publications from the laboratory:

Zhang et al, Nat Commun 2018; Frye et al, Nat Commun 2018; Zhang et al, Development 2018; Wang et al, Development 2017; Martina-Almedina et al, J Clin Invest 2016; Martinez-Corral et al, Circ Res 2015; Stanczuk et al, Cell Rep 2015; Tatin et al, Dev Cell 2013; Lutter et al, J Cell Biol 2012; Bazigou et al, J Clin Invest 2011.

Work description:

The selected candidate(s) will work on one of the following topics: 1) functional characterisation of tissue-specific lymphatic endothelial progenitor cells (as part of an ERC-funded project), 2) identification and functional characterisation of vascular-bed specific genes, or 3) elucidation of disease mechanisms in vascular malformations. In addition, one position will be in collaboration with the group of Ingvar Ferby at Uppsala University (http://www.imbim.uu.se/forskargrupper/cancer/ferby-ingvar/), exploring how vesicular trafficking and compartmentalisation of growth factor receptors instruct behaviour of epithelial and endothelial cells using e.g. live-cell imaging approaches.

Qualifications:

We are looking for highly motivated individuals with a PhD and research background in molecular or cell biology, developmental biology or biochemistry, and a proven track record of successful scientific work. Strong background in molecular/cell biology, mouse genetics, flow cytometry and/or imaging is required.

How to apply:

To apply, please send your CV together with the names of three references and a short description of yourself and the motivation to join the group to: taija.makinen@igp.uu.se

The position is open until 28 December 2018, or until suitable candidate(s) is found.

PhD PostDoc positions in Research Programs Unit of the Faculty of Medicine UH

22.10.2018 | Ajankohtaista

Research Programs Unit of the Faculty of Medicine is a top-quality research environment at the University of Helsinki, a leading European university with a strong life science research, and cancer research in particular. The unit is located in Biomedicum Helsinki close to the Helsinki University Central Hospital, and it provides state-of-the-art core facilities for genomics, proteomics, imaging, and bioinformatics.
PhD candidate and post-doctoral fellow (or bioinformatician/computational biologist) in the field of functional genomics (starting early 2019)

We are seeking a highly motivated and talented individual for working in the field of functional epigenomics. The focus of the lab is to investigate the interplay between transcription factors and oncogenes using modern genome-wide methods for regulatory genomic features and chromatin architecture. The group belongs to the Applied Tumor Genomics Program (starting from 2019) in the Research Programs Unit of the Faculty of Medicine in University of Helsinki providing an excellent research environment with strong focus on cancer research.

We offer a position in a young, multi-disciplinary and teamwork-oriented group that will be comprised of both computational and wet-lab scientists. The ideal candidates will be involved in generation and analysis of functional genomics datasets from next-generation sequencing methods such as ATAC-seq, Hi-C, ChIPseq, as well as CRISPR-based approaches.

– For post-doctoral fellows, the candidate should have a PhD degree in computational biology, bioinformatics or other fields with strong background in programming languages. Demonstrated skill and prior experience in the analysis of high-throughput omics datasets is required and candidates with proven track record in terms of publications will be given preference.

– For PhD students, the candidate should have a Master’s degree in any field of life sciences, other translational programs or quantitative sciences with a particular interest in molecular biology and functional genomics. A good understanding of biochemistry, genomics experiments and bioinformatics is expected. Prior experience in generating experimental omics datasets is an asset but not a requirement.

With English as a working language, excellent oral and written communication skills are required. Salaries are based on the salary system for Finnish universities (YPJ). Details on the project and other informal queries are very welcome and should be sent to biswajyoti.sahu@helsinki.fi. Applications will be considered on a rolling basis till a suitable candidate is found.

Applications should be in form of a single-pdf containing a one-page cover letter describing your research goals, interest and motivation together with recent curriculum vitae (CV) including publications. In addition, two-three reference letters with their contact details must be sent to: biswajyoti.sahu@helsinki.fi

Research Programs Unit
Faculty of Medicine
University of Helsinki
Tutkimusohjelmayksikkö, PL 63 (Haartmaninkatu 8), FI-00014 Helsingin yliopisto Forskningsprogramenheten, PB 33 (Haartmansgatan 4), FI-00014 Helsingfors universitet, Research Programs Unit, POB 63 (Haartmaninkatu 8), FI-00014 University of Helsinki, https://www.helsinki.fi/en/faculty-of-medicine/research-programs-unit

PhD student position in the Department of Biochemistry/Biotechnology, University of Turku

22.10.2018 | Ajankohtaista

Background information

A PhD student position is open in a newly started three-year project New Modalities: Recombinant Protein Platform for Drug Lead Discovery. The project aims to establish efficient strategies and tools for the development and optimization of protein based targeting molecules (antibodies and protein scaffold based binders) for drug development. The project also explores novel strategies to develop advanced antibody based drug candidates, including bispecific antibodies and antibody oligonucleotide conjugates. The project is funded by the Business Finland and is carried out in collaboration with prof. Pasi Virta (Dept. of Chemistry, UTU) and industrial partners.

Position

The PhD student will join the Antibody engineering research group at Unit of Biotechnology, Department of Biochemistry, University of Turku, Finland. The group has an extensive expertise in research related to recombinant antibodies and in vitro evolution techniques. The student will focus on the development of advanced biomolecular compounds including bispecific antibodies and protein conjugates. The funding from the aforementioned project is available for the period 1.11.2018 – 31.8.2021.

Requirements

We are seeking a highly-motivated PhD student interested in protein engineering and drug development. The applicant should hold a masters degree in biotechnology, biochemistry or biomedicine (or equivalent, or the graduation should be expected in 2018). Good spoken and written English are required. The doctoral training will contain also participation and presentations in international conferences.

Salary

The salary is determined in accordance with the university salary system for teaching and research personnel. For doctoral candidate the salary is at levels 2 – 4 on the job demands chart, where the task specific salary component is 2005,71 – 2500,06 euros per month. In addition, a personal work performance component will be paid. The personal work performance component is a maximum of 46.3 % of the task specific salary component. Trial period is 6 months.

Conditions and application deadline

The position will start at the earliest in Nov 1st 2018 .There is a trial period of six months. Send your application, CV and motivation letter at the latest Oct 18th 2018 via the electronic application form of the University of Turku. The link to the electronic application system is found at the beginning of this announcement (Apply for the job) http://www.utu.fi/en/university/come-work-with-us/open-vacancies/Pages/home.aspx

Additional information is given by Associate Professor Urpo Lamminmäki (urplammi@utu.fi)

Three Bachelor’s Thesis or Master’s Thesis/Internship opportunities – Novo Nordisk Foundation Center for Basic metabolic Research (CBMR), SUND, University of Copenhagen

19.10.2018 | Ajankohtaista

https://karriere.ku.dk/employer/jobs/Novo-Nordisk-Foundation-Center-for-Basic-Metabolic-Research

We are looking for three motivated and self-driven Bachelor (Thesis work) or Master students (Thesis or Internship) within the fields of biomedicine, clinical medicine, bioinformatics, pharmaceutical sciences, human biology or related fields.

Location: Novo Nordisk Foundation Center for Basic metabolic Research (CBMR), SUND, University of Copenhagen. No salary. Work language English.

Titles and starting times for the projects are:

1) Targeting Cyr61-Mediated Adipose Angiogenesis to Treat Obesity – Starting time is from the beginning of 2019 or later, Laboratory experience is an advantage.

2) Uncovering the Genetic Link between Depression and Type 2 Diabetes – Starting time as soon as the student is ready to start

3) Do healthy lifestyle factors decrease the impact of weight gain on cardio-metabolic risk in Danish individuals? – Starting time is as soon as the student is ready to start to next year.

Background for each project and related information can be found from the link along with the contact details!

Postdoc Fellow Scholarship in Research of the Evolution of Multicellularity at the Medical Faculty, Lund University, Sweden

17.10.2018 | Ajankohtaista

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has 42 000 students and 7 400 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition. The Faculty of Medicine is a part of Lund University, and is responsible for education and research within medicine and healthcare. Our academic programs are closely linked with the healthcare system and are firmly anchored in the faculty’s strong research tradition. Our research spans a broad field within experimental preclinical research, near-patient clinical research and health sciences research. The Faculty of Medicine, with its 1,800 employees and 2,700 students in Lund and Malmö, is a knowledge-intensive meeting place for students, teachers and researchers from all over the world.

The Department of Laboratory Medicine is one of six departments at Lund University’s Faculty of Medicine. In addition to leading world-class research within cancer and genetics, we also utilize tumors as models to explore the success and evolution of multicellularity over Earth history. These explorations are conducted in collaboration with expertise at departments at the Faculty of Natural Sciences.

Scholarship
Animals are the most successful versions of multicellular life on Earth, in terms of size and complexity. However, exactly why this success came about remains enigmatic. External factors are often invoked, like an increase of free oxygen. In contrast, we focus on the evolutionary changes within tissue that may have facilitated the success.

Our overall aim onwards is to test implications of the hypothesis of refined stemness control (Hammarlund et al., 2018), and to further explore the model with particular focus on oxygen and carbonic anhydrases. Newly defined questions can be explored within cell- and molecular biology techniques (e.g. RNA-sequencing, cell culturing, immunohistochemistry), bioinformatics, and in vivo biological experiments. In addition, the explorations would involve broad literature studies.

We seek a brave and ambitious postdoc willing to explore uncharted scientific terrain.

Qualifications required
1. The applicant should have an interest in the evolution of life and broad experience in biology or of geobiological questions.
2. Applicant should hold a PhD degree (after 2015-11-01) in the biological sciences with experience in transcription factor regulation, bioinformatics and/or wet lab experiments.
3. Familiarity with processes pertaining to biomineralization is an advantage.
4. The applicant should be used to defining and exploring research questions independently.
5. An ambitious scholar, keen on learning.
6. Good communication skills and be able to interact efficiently in a team.
7. Excellent spoken and written English.

The applicant should not have been employed by Lund University within the last two years in order to be able to receive a scholarship. PhD degree should not be more than three years old at the last day of applying.

Last day for applying: 1st of November.

More information and applying at https://www.nature.com/naturecareers/job?id=657429

Open position for a PhD candidate and post-doctoral fellow (or bioinformatician/computational biologist) in the field of functional genomics at the University of Helsinki

17.10.2018 | Ajankohtaista

Research Programs Unit of the Faculty of Medicine is a top-quality research environment at the University of Helsinki, a leading European university with a strong life science research, and cancer research in particular. The unit is located in Biomedicum Helsinki close to the Helsinki University Central Hospital,
and it provides state-of-the-art core facilities for genomics, proteomics, imaging, and bioinformatics.

PhD candidate and post-doctoral fellow (or bioinformatician/computational biologist) in the field of functional genomics (starting early 2019)

– For post-doctoral fellows, the candidate should have a PhD degree in computational biology, bioinformatics or other fields with strong background in programming languages. Demonstrated skill and prior experience in the analysis of high-throughput omics datasets is required and candidates with
proven track record in terms of publications will be given preference.

– For PhD students, the candidate should have a Master’s degree in any field of life sciences, other translational programs or quantitative sciences with a particular interest in molecular biology and functional genomics. A good understanding of biochemistry, genomics experiments and bioinformatics
is expected. Prior experience in generating experimental omics datasets is an asset but not a requirement.

With English as a working language, excellent oral and written communication skills are required. Salaries are based on the salary system for Finnish universities (YPJ). Details on the project and other informal queries are very welcome and should be sent to biswajyoti.sahu@helsinki.fi . Applications will be considered on a rolling basis till a suitable candidate is found.

FIMMPOD Annual Call for Postdoctoral Researchers

15.10.2018 | Ajankohtaista

The FIMMPOD Programme at the Institute for Molecular Medicine Finland (FIMM) is now seeking outstanding international candidates for two Postdoctoral Researcher positions.

Applications are sought in the areas of

1) computational systems medicine and

2) epigenetics of complex diseases and traits.

Candidates are expected to hold a PhD degree in a suitable field and to be fluent in English.

More information about the positions and qualifications can be found from the FIMM website (https://www.fimm.fi/en/open-positions) or the University of Helsinki website (http://www.helsinki.fi/recruitment/index.html).

Application deadline is 28.10.2018 at 23.59 EEST. Applications are submitted by completing the application form and submitting a CV and a cover letter as a single PDF file (max 5 pages) in English at: https://www.helsinki.fi/fi/avoimet-tyopaikat/postdoctoral-researchers-2018.