OPEN POSITION FOR MASTER’S THESIS WORKER – University of Eastern Finland, Institute of Biomedicine


We are looking for student(s)who are curious about cell and molecular biology and interested in cancer research.

We are studying molecular mechanisms of tumor stroma interaction focusing on melanoma cells and macrophages. The role of immune cells in tumor dissemination is well established yet the mechanisms that recruit the immune cells and regulate their function in the tumor microenvironment are poorly understood at the moment and are the targets of our research. In this master’s thesis project you will study the role of tumor cell derived extracellular vesicles (EVs) on macrophage polarization and behavior. EVs are small plasma membrane derived particles, which are important signaling mediators in our body. In this project, the content of EVs, the proteome, will be elucidated, and their effects on macrophages.

In this master’s thesis project you will do and learn cell culturing, EV isolation, immunohistochemical methods, confocal microscopy, protein and RNA analyses. Our institute has first-class facilities for modern biomedical research. Joining us as a master’s thesis student means an outstanding opportunity to put your theoretical knowledge into practice.

The position will be filled after a suitable person is found, and the project (lab work) will start in the beginning of January 2021, or as agreed. You can start working in the project full-time or part-time.A scholarship (1250 €/month, ~full-time working) will be paid. Additional information: Docent Sanna Pasonen-Seppänen.

Please, send your informal application including your CV and the transcript of academic record by 18.11.2020 to Sanna Pasonen-Seppänen, Sanna.Pasonen@uef.fi, Institute of Biomedicine, University of Eastern Finland