Postdoc position at Smita Saxenas lab at University of Bern, Switzerland
5.5.2017Postdoctoral positions are available in the laboratory of Smita Saxena in the Department of Neurology, University hospital, University of Bern, Switzerland. The newly established Center for Experimental Neurology in the Department of Neurology has state-of-the-art labs and equipment and fosters a highly vibrant scientific exchange between clinical and experimental research groups. We are seeking postdoctoral candidates who are passionate about deciphering the role of dendrites and synapses in promoting neurodegeneration. The project, funded by the European Research Council, strives to understand the relationship between early deficits in neuronal circuits and the pathogenic alterations within disease vulnerable
We are seeking postdoctoral candidates who are passionate about deciphering the role of dendrites and synapses in promoting neurodegeneration. The project, funded by the European Research Council, strives to understand the relationship between early deficits in neuronal circuits and the pathogenic alterations within disease vulnerable neurons. The main research interests of our laboratory focus on the mechanistic and therapeutic studies of neurodegenerative diseases such as Motor neuron diseases and Spinocerebellar ataxia. Our multidisciplinary approach uses transgenic disease models and combines state-of-the-art small cell number proteomics, transcriptomics, calcium imaging, viral mediated gene expression, neuronal tracing, chemogenetics and behavior paradigms to elucidate neuron specific alterations driving disease in defined population of neurons (Ruegsegger et al., Neuron 2016, Ruegsegger et al., Acta Neuropathologica 2016, Filezac de L’Etang et al., Nature Neuroscience 2015 and Saxena et al., Neuron 2013). The successful applicant should have a PhD degree in biological sciences with an excellent track record, a strong background in neurosciences, a broad working knowledge of mouse genetics, stereotactic surgeries in rodents, molecular and cellular biology, confocal, 2-photon imaging, and
The successful applicant should have a PhD degree in biological sciences with an excellent track record, a strong background in neurosciences, a broad working knowledge of mouse genetics, stereotactic surgeries in rodents, molecular and cellular biology, confocal, 2-photon imaging, and behavioral assays. The candidate is expected to work independently in a small team, design experiments and perform research. Prior experience in cerebellum or spinal cord research is a plus. Good communication skills in English are required. Starting date is negotiable but
Good communication skills in English are required. Starting date is negotiable but preferred start is in fall. Interested candidates should submit a statement of research experience and career goals, a current CV and the names of three references to smita.saxena@izb.unibe.ch