Postdoctoral Fellow Position in Mu Opioid/Pain research in the Pan laboratory in Department of Neurology and Molecular Pharmacology Program at Memorial Sloan-Kettering Cancer Center13.1.2020
One postdoctoral fellow position is immediately available in the Pan laboratory in Department of Neurology and Molecular Pharmacology Program at Memorial Sloan-Kettering Cancer Center. The research in Pan’s lab focuses on molecular and cellular mechanisms of mu opioid actions using state-of-the-art molecular, biochemical, chemical and pharmacological approaches. providing the foundation of developing novel analgesic drugs for pain treatment (see Pharmacol Rev. 65:1257-1317, 2013; J Clin Invest. 125:2626-2630, 2015; J Clin Invest, 127:1561-1573, 2017).
The applicant(s) will participate in one or two of the projects in the following areas:
1) Investigating the mechanisms underlying alternative splicing of the mu opioid receptor gene (OPRM1) and its relevance to opioid pharmacology;
2) Mapping and characterizing mu agonist-induced receptor-protein interactions that contribute to opioid actions;
3) Determining molecular mechanisms of mu opioid-induced tolerance, respiratory depression and reward; and
4) Defining molecular mechanism of the novel analgesic drugs.
The laboratory will also provide a wealth of molecular, biochemical and pharmacological expertise to facilitate both research and career development. Highly-motivated candidates with experience in molecular biology and biochemistry or behavioral pharmacology are encouraged to apply. The positions are fully funded by the grants from NIDA. Salary will be commensurate with qualifications, laboratory experience and institutional guidelines.
Applicants interested in the position should send their curriculum vitae, along with contact information for three references, to Dr. Ying-Xian Pan (firstname.lastname@example.org).