Postdoctoral Scientist in Molecular Neuroscience Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford Grade 7: £32,236 – £39,609 p.a.
exciting opportunity has been created for a Senior Postdoctoral
Scientist to join the interdisciplinary research programme studying
Parkinson’s disease and related synucleinopathies in the Nuffield
Department of Clinical Neurosciences led by Associate Professor
Laura Parkkinen. The group focuses on elucidating biochemical and
genetic signatures in human brain and biosamples to assist with
understanding disease pathogenesis but also to provide diagnostic
biomarkers for Parkinson’s disease and dementia. These are much
needed to improve early diagnosis of PD and assessing the efficacy of
disease-modifying therapies in a biologically-targeted manner.
postholder will elucidate biochemical and genetic signatures in human
brain and biosamples to assist with understanding disease pathogenesis
but also to develop biomarkers
for Parkinson’s disease and dementia. They will also develop
alpha-synuclein seeding assay (RT-QulC) as an early predictive
biomarker, monitoring disease progression and stratifying between
different synucleinopathies and examine their toxicity and infectivity
postholder must hold a PhD in molecular neurosciences or in a field
directly relevant to translational neuroscience. They must have
substantial experience in protein chemistry,
cell culture, molecular genetics and neuropathology. Previously
demonstrated research acumen, a track record of successful
publication(s) and clear potential for future success is vital.
postholder is also expected to possess excellent skills in scientific
communication, both orally and in writing are expected and have a strong
drive to pursuing a career
in academia. Previous experience of working with human brain and
peripheral samples is highly desirable, including familiarity with basic
The post is full-time for a fixed-term until 31 January 2021 in the first instance and the position is to start immediately.
Only applications received before 12.00 midday on 13 January 2020 will be considered. Interviews will be held as soon as possible