Ajankohtaista

We are looking for two highly motivated and dynamic researchers, who will join a team of molecular and cellular biologists and computational scientists studying how human neurodevelopmental disorders arise during brain development and maturation

The Research Centre

The Biotech Research and Innovation Centre (BRIC) is a research centre of excellence for biomedical research, focusing on disease-oriented basic research, at the Faculty of Health and Medical Sciences, University of Copenhagen. BRIC hosts 24 independent research groups that perform basic and translational research aimed to understand diseases like cancer, neurological and metabolic disorders.
For further information about the Khodosevich group and BRIC: http://www.bric.ku.dk/

Our research

Our group studies mechanisms that are responsible for neuronal specification, positioning and circuit formation during prenatal and postnatal brain development, and how these mechanisms are impaired in neurodevelopmental disorders such as schizophrenia, epilepsy, autism. We analyse mouse models of neurodevelopmental disorders and human tissue to identify those neurons that are affected in a particular disorder, and how dysfunction of affected neurons contribute to brain circuit malformation and underlie cognitive impairment in human patients. Our work is highly interdisciplinary, from high-throughput analyses of single neurons in human and mouse tissues to functional studies of disease relevant genes in mouse models in vivo or in human cell cultures in vitro. Importantly, we have international network of collaborators for studying human brain disorders by variety of frontline technologies and cooperate with several Hospitals for most efficient transition from basic to translational studies.

Your job

Two postdoctoral positions are available:

1.You will investigate how human neurons are affected in neurodevelopmental disorders by comparative analysis of healthy and disordered brains. You will implement single cell transcriptomics pipelines that are established in the lab with follow-up analyses of disease-causing genes in human cell cultures and in mouse models.
2.You will investigate how neuronal circuits are affected in mouse models of neurodevelopmental disorders. You will study this question by analysing brain anatomy, neuronal morphology and cellular properties of affected neurons.

Profile

We are looking for highly motivated and enthusiastic scientists with the following competences and experience:

Essential:

You have a PhD in Life Sciences, preferably in Neuroscience, Developmental Biology or Brain disorders

• You are highly experienced in molecular and cellular biology, and previous single cell work is an advantage
• You are particularly interested in understanding of how neurodevelopmental disorders arise and in finding new targets for translational research
• You have and excellent track record with several published papers where your contribution was essential
• You have proficient communication skills and ability to work in teams
• You have excellent English skills written and spoken

We offer

• A 2.5 to 4-year contract (possibly extendable) with a competitive salary and social benefits (e.g. social security, health coverage, parental leave)
• Access to state-of-the art tools and infrastructure
• Tailored support in raising competitive funds and communicate your research
• A stimulating and supportive international research environment

We have weekly internal seminars with PhD students and postdocs presenting their work as well as external seminars with international speakers. BRIC also hosts several research clubs; Hematology club, Chromosome Biology club, Stem cell club and Single Cell Transcriptomics seminar series. The Institute has an association for students and postdocs (ASAP), a PhD programme (MoMeD) and a Postdoc Career Programme (PCP). BRIC has extensive international collaborations and actively participates in the European alliance, EU-LIFE consisting of 13 excellent life science research institutions and is part of the EU-funded LIBRA initiative to obtain gender balance in life science research.

BRIC has a highly international profile (over 60% international researchers) and English as working language. An International Staff Mobility Office at UCPH supports and guides international researchers through your initial steps in Denmark (e.g. residence and work permits, tax and pension, banking, medical care, childcare). They also offer a dual career network open for spouses of our researchers.

Start date: preferably September 2018 or after agreement

For further information regarding the position, please contact Associate professor Konstantin Khodosevich on e-mail: konstantin.khodosevich@bric.ku.dk

Terms of salary and employment
Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary starts at 33,224.48 DKK/4450 Euro. An additional 17.1 % monthly contribution to pension will be paid by the employer. Depending on qualifications, a higher salary may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

Application

Your application must be submitted electronically by clicking ‘Apply now’ below or via BRIC’s website on http://www.bric.ku.dk/jobs/. The application must include the following documents/attachments – all in PDFformat:
1. Motivated letter of application (max. one page), where you also indicate which of two advertised positions you would like to apply for.
2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
4. List of publications.

Letters of recommendation
Furthermore, the shortlisted applicant should provide two letters of recommendation. To be taken into consideration, the letter must be signed by the supporting person on paper with institutional letter head and in PDF-format and send to konstantin.khodosevich@bric.ku.dk with subject “name candidate-postdoc-2018”; preferably by the supporting person. The letters should be received 1 week after being notified about shortlisting. Please make sure that an easy match between the recommendation letter and the individual applicant is possible.

Application deadline: July 8, 2018
We reserve the right not to consider material received after the deadline, and not to consider applications or letters of recommendation that do not live up to the abovementioned requirements.

Application procedure

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/

BRIC and University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career. …