This
Academy of Finland and Novo Nordisk-funded project involves studying
genetics and molecular biology in bone metabolic diseases.
Please see https://www.helsinki.fi/en/researchgroups/metabolic-bone-diseases
for more information. You will study the genetics of skeletal diseases
and molecular biological consequences of skeletal disease in zebrafish
models, primary cultures, and cultured cell lines. You will perform NGS
data analysis and imaging and molecular biology
analysis of the zebrafish and cells. You will also supervise
Master’s/PhD students, prepare and publish scientific manuscripts, and
write grant applications.
Qualifications
A
successful candidate holds a PhD in life or biomedical sciences.
Experience and qualification in genetics, biochemistry or animal
physiology and working with cell cultures is obligatory. In addition,
knowledge of molecular biology studies and imaging is essential.
Knowledge of NGS data analysis, bone biology, skeletal diseases, and
zebrafish studies will be advantageous.
The salary will be based on the Universities salary scheme for teaching
and research personnel. A successful candidate is expected to start in
May 2019, or according to the agreement.
Application and questions should be sent to
minna.pekkinen(at)helsinki.fi or outi.makitie(at)helsinki.fi, with the
subject line “open postdoc position.” Applications are invited immediately, and the position will be filled when a suitable candidate is found.
A
Ph.D. student position is available at the University of Helsinki and
Folkhälsan Research Center, Biomedicum in Meilahti, Helsinki, Finland.
Our research involves the clinical and genetic characteristics
of osteoporosis, skeletal dysplasias, early-onset obesity, and mineral
metabolism. Please see https://www.helsinki.fi/en/researchgroups/metabolic-bone-diseases
for more information.
We offer you:
• an opportunity to work in a high-quality group of bone researchers
• a chance to be involved in cross-field science and develop new techniques for the research of
bone diseases in cell biology, molecular biology, clinical medicine, and animal work
• an inspiring research environment on the largest biomedical research campus in Finland
• a chance for completing a Ph.D
• financial support through a grant with the possibility of applying for University Graduate
Schools later on
What is expected of you:
• MSc degree in biological or biomedical sciences field
• high motivation level and work morale
• capability to work both independently and in group
• to manage overlapping projects
• previous experience in genetics, cell biology or molecular biology is required
• experience in laboratory work with cell culture
• Skills and training in working with model animals (zebrafish) are an advantage. The project
will involve animal work
• adequate written and oral skills in the English language
• a possibility of interviewing at Folkhälsan Research Center in person (not via Skype)
The start time is negotiable, but spring 2019 is preferable. Please address your queries and applications in English, with CV, to Minna Pekkinen, minna.pekkinen(at)helsinki.fi, tel. 050 4485670, 31.3.2019 at the latest.
Projektitutkija, farmasia/biofarmasia, farmasian laitos, Kuopion kampus
Haettavana olevaan tehtävään liittyvä tutkimus on osa EU:n Horisontti 2020 -puiteohjelman rahoittamaa EDCMET-hanketta (https://cordis.europa.eu/project/rcn/218991/factsheet/en), jonka tavoitteena on selvittää hormonihäirikköjen metabolisten haittavaikutusten mekanismeja ja kehittää tutkimuksessa tarvittavia menetelmiä. Projektitutkijan työnkuvaan kuuluvat tutkimuksen tekeminen ja tutkimuksen avustavat tehtävät hankkeessa. Ensisijaisena työtehtävänä on kehittää ja optimoida tumareseptoriaktivaation tutkimiseen tarvittavia solupohjaisia ja reportterigeenin aktiivisuuden mittaamiseen perustuvia menetelmiä. Tehtäviin kuuluvat myös menetelmissä tarvittavien DNA-konstruktien kloonaus, reagenssien valmistus, solujen ylläpito ja muut yleiset laboratoriotehtävät. Projektitutkijan odotetaan tarvittaessa osallistuvan myös muihin ryhmän tutkimustehtäviin.
Tehtävään valittavalta
henkilöltä edellytetään suoritettua filosofian maisterin tai vastaavaa
tutkintoa biokemiasta, molekyylibiologiasta, toksikologiasta tai muulta
soveltuvalta alalta. Henkilöllä tulee olla syvälliset
tiedot ja aiempaa käytännön laboratoriokokemusta
puhdastilatyöskentelystä ja nisäkässoluviljelystä sekä vähintään
perustiedot transfektiomenetelmistä, reportterigeenianalyyseistä ja
plasmidikloonauksesta. Tehtävän menestyksekäs hoitaminen edellyttää
omatoimisuutta,
kykyä itsenäiseen tiedonhakuun ja töiden suunnitteluun, kykyä tehdä
yhteistyötä poikkitieteellisessä ja kansainvälisessä ympäristössä sekä
hyvää suomen ja englannin kielen kirjallista ja suullista taitoa.
Tehtävä täytetään määräajalle 1.4.2019-31.12.2020.
Määräaikaisuuden perusteena ovat määräaikaiset tutkimustehtävät hankkeen
osaprojektissa.
Tehtävän palkkaus määräytyy yliopistojen opetus- ja
tutkimushenkilöstön palkkausjärjestelmän mukaisesti vaativuustasolle 2
(2033,29 €/kk). Tehtäväkohtaisen palkanosan lisäksi maksetaan
henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on enintään
50% tehtäväkohtaisesta palkanosasta.
Lisätietoja: projektitutkija Jenni Küblbeck, 029 4454111, jenni.kublbeck@uef.fi,
ja hakumenettelyn osalta hallintosihteeri Seija Koistinen, 029 4454324, seija.koistinen@uef.fi.
Uuden työntekijän tullessa yliopiston palvelukseen käytetään koeaikaa.
– ansioluettelo
– julkaisuluettelo
– kopiot tutkintotodistuksista ja kielitaitoa osoittavista todistuksista, ellei kielitaito ilmene tutkintotodistuksista
– motivaatiokirje (max 1 sivu)
– muut dokumentit, jotka voivat vaikuttaa valintaan (max 3 sivua)
– kahden suosittelijan yhteystiedot
Hakemus tulee jättää viimeistään 15.3.2019 sähköisellä hakulomakkeella.
Two
positions available at the Faculty of Medicine to study the role of
microbes and microbial infections in blood malignancies. Both positions
provide ample opportunities to develop expertise on next-generation
sequencing -based diagnostics, computational
genomics, and infectious diseases together with the top national
clinicians, haematologists, bioinformaticians, microbiologists, and
geneticists.
Particularly, we are looking for:
1)
A student with a good knowledge on wet laboratory techniques and
enthusiasm to develop advanced sample preparation solutions
for the analysis of complex hostmicrobe samples. The candidate has a
background in microbiology, biotechnology, or genetics, and is familiar
with the major wet-laboratory techniques in molecular biology. He or she
can design and conduct laboratory experiments
independently and has interest in developing skills in the analysis of
giga-size biodata available in the laboratory. Prior work experience in a
research laboratory is an advantage as well as experience in working
with RNA, DNA, and/or clinical/human samples.
2) A student with experience in bioinformatics and/or analysis of large-scale biodata. The candidate has a background in bioinformatics, computer science, engineering, or genetics and masters fluently at least one of the following: Python, Perl, R, C++, or Java. The applicant has a proven ability to operate in Linux environment and is interested in developing computational solutions for the integrated analysis of genetic and clinical data and sequencing-based analysis of host-microbe infections. Experience in parallel programming and machine learning is an asset as is prior work experience on analysis of next generation sequencing data and/or large biodata collections.
Both
candidates must have good skills in written and spoken English. They
should apply critical thinking, have a proactive mindset,
and enjoy working in a multi-disciplinary team. They should have
excellent communication and interpersonal skills and are expected to
communicate results to diverse audiences. The positions are funded by
project grants from the Academy of Finland, the Finnish
Funding Agency for Innovation / Business Finland, and The Finnish
Cultural Foundation. The appointments are initially for 6 months with a possibility of extension.
For further information, please contact Dr. Teija Ojala (teija.ojala(at)helsinki.fi)
or Dr. Matti Kankainen (matti.kankainen(at)helsinki.fi).
To apply for the position,
please send your motivation letter and CV, including a list of
publications and contact information for two references to Dr.
Kankainen.
Applications will be reviewed and considered as they are received. Application deadline is 24.03.2019.
Suomen Solubiologit ry onnittelee apulaisprofessori Lotta-Riina Sundbergia Ellen ja Artturi Nyyssösen tunnustuspalkinnon saamisesta! Lotta-Riina Sundberg on merkittävästi edistänyt tieteellistä tutkimusta Jyväskylän yliopistossa sekä kansainvälistä tutkimusyhteistyötä.
The University of
Helsinki is an international scientific community of 40,000 students and
re-searchers. It is one of the leading multidisciplinary research
universities and
ranks among the top 100 international universities in the world.
We are an equal opportunity employer and offer an attractive and
diverse workplace in an inspiring environment with a variety of
development opportunities and benefits.
The Faculty of Biological and Environmental Sciences (https://www.helsinki.fi/en/faculty-of-biological-and-environmental-sciences)
is Finland’s most high-profile and extensive hub of research and
teaching in the field. The Faculty educates experts to meet the needs of
universi-ties, research institutes, government, schools and the
business sector.
The Faculty of Biological and Environmental Sciences also has
biological stations at Kilpisjärvi, in Lapland, and Lammi, in Southern
Finland, as well as a Zoological station at Tvärminne on the coast of
the Baltic Sea (https://www.helsinki.fi/en/faculty-of-biological-and-environmental-scien…).
The University of Helsinki’s Faculty of Biological and Environmental Sciences invites applications for three positions of
UNIVERSITY LECTURERS IN MOLECULAR AND INTEGRATIVE BIOSCIENCES
The fields of research and teaching of the university lecturer
shouldinclude one or more of the following: molecular biosciences,
biochemistry, structural biology, bioinformatics, genetics, genomics,
microbiology, cell biology, developmental biology, physiology and
neuroscience.
Molecular and Integrative Biosciences Research Programme is one of
the three Research Programmes in the Faculty of Biological and
Environmental Sciences. The areas of strength of the Programme are cell
biology, developmental biology, genetics, neurobiology, structural
biology and virology. The research and teaching activities are located
on the Viikki Campus (https://www.helsinki.fi/en/viikki-campus) and are supported by state-of-the-art infrastructures including core facilities https://www.helsinki.fi/en/helsinki-institute-of-life-science/hilife-res…)
for e.g. different model organisms, DNA sequencing, proteomics,
structural biology, metabolomics, lipidomics, and light- and electron
microscopy including two-photon confocal and cryo-electron microscopes.
The university lecturer is expected to contribute and to develop both
teaching and research in the focus areas of the Molecular and
Integrative Biosciences Research Programme. Teaching by the lecturer is
given primarily in the Bachelor’s programs in Biology and Molecular
Biosciences as well as Master’s programs in Genetics and Molecular
Biosciences ,Neuroscience and Microbiology and Microbial Biotechnology.
In addition, the university lecturer will counsel and supervise
undergraduate and postgraduate students and participate in the
development of Bachelor’s, Master’s and doctoral programmes in the
Faculty. The expected minimum amount of yearly contact teaching is
100-120 hours.
An appointee to a lectureship shall hold a doctoral degree and have
scholarly qualifications and experience in the conduct of scientific
research, along with the ability to provide top-level research-based
teaching.
When considering the applicant’s qualifications, attention will be
given to scientific publications, teaching experience, pedagogical
training and competence as well as merits in development of teaching.
Account shall also be taken of the applicant’s success in obtaining
external research funding, international research experience, activity
in the scientific community, positions in Finnish and international
organizations, and visions for research and teaching in the future. The
three university lecturers will be recruited to complement each other
and the existing research and teaching activity at the Faculty.
There is no requirement to be proficient in Finnish for foreign
citizens, non-native Finnish citizens or citizens who have not been
educated in Finnish or Swedish. To successfully attend to the duties of
the position, the appointee must have good skills in English. If the
appointee is not proficient in Finnish or Swedish, he/she is expected to
acquire moderate proficiency within a reasonable time after the
appointment. Support for language studies is offered.
The annual gross salary for an university lecturer amounts to
approximately 35000-68000 €, depending on the appointee’s career stage
and scholarly qualifications.
Standard Finnish pension benefits and occupational health care are provided for University employees.
Finland is a member of the EU, has high quality free schooling (also
in English), generous fami-ly benefits and healthcare, and was recently
ranked as the best country in the world for expat families. Helsinki is
in the world’s top ten most livable cities. The University of Helsinki
is a top 100 ranked university in most ranking lists, and is currently
investing heavily in life sciences research (see https://www.helsinki.fi/en/helsinki-institute-of-life-science).
Applicants are requested to enclose with their applications the following documents in Eng-lish:
1) CV
2) A report (max. 3 pages) of experience and merits which are of
relevance for the evaluation of fields of expertise and skills in
teaching (https://www.helsinki.fi/sites/default/files/atoms/files/bytdk_teaching_s…)
3) A report (max. 3 pages) on the applicant’s previous research
activities, and a plan for how the applicant intends to develop their
research and focus their activities in the future
4) A numbered list of publications in English and other works with which
the applicant wishes to demonstrate their competence and merits, with
five most important publications highlighted with brief explanations.
Applications must be submitted through the University’s electronic
recruitment system by clicking on the link below. Internal applicants
(i.e., current employees of the University of Helsinki) must submit
their applications through the SAP HR portal. The deadline for
applications is 31.3.
Further information:
• On the position and on the research environment: Dean Jaakko Kangasjärvi jaak-ko.kangasjarvi (at) helsinki.fi
• On the recruitment process: Human Resources Specialist Harri Hamara, harri.hamara (at) helsinki.fi
• Technical support for using the recruitment system: rekrytointi (at) helsinki.fi
Location: Australian Regenerative Medicine Institute (ARMI), 15 Innovation Walk, Monash University, Clayton
Remuneration: Annual living allowance based on Monash University’s
Research Training Program (RTP), stipend of $27,872 per annum (2019 rate
– indexed annually)
The Opportunity
The Zenker group is seeking an enthusiastic PhD candidate interested
in cell biology and microscopy to uncover the real-time rearrangements
of the inner skeleton of a cell during embryonic development. The
successful applicant will gain extensive expertise in live imaging using
various microscope systems, mouse husbandry, genotyping, cell culture
systems, cloning, immunostaining, mouse embryo dissection, injections
and imaging, drug treatments and computational image analysis.
Every cell has an internal skeleton composed of filament-like
structures called microtubules. Remarkably, these structures can rapidly
re-organize their entire network to allow a cell to change its shape,
function and fate. However, most studies on microtubule dynamics have
been limited to simplified 2D cell culture systems or fixed tissues.
Thus, the accurate spatial-temporal regulation of microtubule
remodelling in intact tissues remains under-explored.
The combined use of state-of-the-art confocal microscopy, molecular
manipulations, and computational image analysis allowed us to identify
an unprecedented form of microtubule growth in the living mouse embryo.
The emanating filaments serve as transport railways to establish
asymmetries in the cellular organization of the embryo. This mechanism
is required for the formation of the pluripotent inner cell mass, which
will give rise to the embryo proper.
Candidate Requirements
The successful applicant must be an Australian resident with the following attributes:
An excellent academic track record in biological sciences
Interest and commitment
Experience in microscopy would be an advantage
Applicants will be considered provided they fulfil the criteria for
PhD admission at Monash University. Details of eligibility requirements
to undertake a PhD at ARMI are available at armi.org.au/careers-education/higher-degree-research.
Candidates will be required to meet Monash entry requirements, which include English-language skills.
Successful applicants will be expected to enrol no later than 1 June 2019.
How To Apply
Supervisor: Dr Jennifer Zenker
Submit your expression of interest to Dr Jennifer Zenker (Jennifer.Zenker@monash.edu) and include the following:
A cover letter that includes a brief statement addressing the
Candidate Requirements and the reason for your interest in the project
A curriculum vitae, including a list of any published works
A full statement of academic record, supported by scanned copies of relevant certified documentation
Contact details of two academic referees
Closing Date
Monday 11 March 2019, 11:55 pm AEDT
If you apply for this position please say you saw it on Bioloxy
Åbo Akademi University is an internationally acknowledged research
university with an extensive responsibility for providing education in
Swedish in Finland. The activities cover research and education in most
disciplines from natural sciences and technology, humanities, pedagogics
and theology, to business and social sciences.
Åbo Akademi University invites applications for a fixed term position as a PhD Student in Cell Biology starting 1.4.2019 within SPACE-Project (42 months) and within BACE-Project (48 months)
Research group
The
Cell Fate lab led by Professor Cecilia Sahlgren is focused on the
fundamental molecular mechanisms that guide cell fate and cell
organization in stem cell differentiation, tissue formation and in
disease such as cancer. Together with collaborators we utilize such
knowledge to develop material-based medical technologies to control
these mechanisms in regenerative and cancer therapies. Coordination of
cells through molecular cell signaling pathways is crucial for the
formation of functional tissues and signaling is often deregulated in
diseases such as cancer, allowing cells to acquire abnormal functions
and pathological remodeling of tissue architecture. The physical,
mechanical and chemical stimuli of the microenvironment also influence
cell signaling and cell fate decisions during development and disease
progression.
Project description
We are seeking 2 ambitious PhD candidates to join our projects on Spatiotemporal
activation of cell functions (SPACE) 1.4.2019-31.8.2022 or
Bioelectronic activation of cell functions (BACE) 1.4.2019-28.2.2023. These
projects form an interdisciplinary approach bringing together
researchers within experimental physics and molecular biology, in order
to activate Notch signalling on demand. The Notch signalling pathway is a
seemingly simple signalling system where the interaction between a
ligand at the surface of one cell and a receptor at the surface of
another gives rise to one active signalling fragment, which regulates
target gene expression. Notch is involved in cell fate specification
during development, usually by facilitating binary cell fate decisions
or by maintaining stem cell fate. Perturbation of the signalling cascade
is a contributing factor in the development of various diseases.
Strictly organised, both spatial and temporal, expression of different
receptors and ligands is essential for proper development of different
organs, with each consecutive activation of Notch driving a specific
morphogenic process. The possibility of controlling Notch receptor
activation by regulating ligand dose and the specific timing of
activation will enable us to better understand different developmental
patterns.
JOB REQUIREMENTS
We are
accepting applications from enthusiastic and highly talented candidates
who are interested in a dynamic, stimulating and ambitious environment
to perform their research and share their scientific knowledge.
We are looking for candidates that meet the following requirements
•The candidate should have a MSc in molecular biology, cell biology, or an equivalent area
Personal qualities
We
are seeking a driven and pro-active applicant with good communication
and interpersonal skills. The applicant should be confident in working
independently, but value developing good working relationships both
within the research group and with collaborators. Knowledge of basic
cell and molecular biological techniques (e.g. mammalian cell culture,
Western Blotting, PCR) is required. Knowledge in e.g. biophysics,
synthetic biology, chemistry or engineering (with strong molecular
background) is an asset.
CONDITIONS OF EMPLOYMENT
We offer
•A challenging job at a dynamic and ambitious environment and in an enthusiastic international, interdisciplinary team.
•Access to world class infrastructure in proteomics, metabolomics, functional genomics, bioinformatics and bioimaging.
•Support with your personal development and career planning.
•Gross
monthly salary is in accordance with the salary system of Finnish
universities based on levels 2 – 4 of the job demand level for teaching
and research personnel. In addition, a salary component based on
personal work performance is paid.
•Doctoral training programme at Åbo Akademi University
SALARY
The
salary for PhD Student is in accordance with the Finnish University
salary system for teaching and research personnel job demand levels 2-4,
where the work specific salary component is 2011,17-2507,62€ per month.
In addition, there is a salary component based on personal work
performance, which is at most 50.00% of the base salary.
APPLICATION
Please submit your electronic application with enclosures below (Submit application, www.abo.fi/jobb). The closing date for applications is March 19th, 2019 at 15.00 Finnish time.
A free-format letter of application (in English)
Copies of the bachelor’s and master’s degree diplomas, including the study record (with grades)
Your CV (in English)
Copies of documents that support the candidates English language skills
Recommendation letter or contact details to references
CONTACT INFORMATION
For
further information, please contact professor Cecilia Sahlgren, group
leader, Cell Biology, Faculty of Science and Engineering, Åbo Akademi
University, e-mail: cecilia.sahlgren@abo.fi or Marika Sjöqvist, PhD, marika.sjoqvist@abo.fi
Åbo Akademi University The
Åbo Akademi profiling research areas include Molecular Process and
Materials Technology, Minority Research, The Sea and Drug Development
and Diagnostics
(https://www.abo.fi/en/about-abo-akademi-research-profiling/). Within
the Drug Development and Diagnostics, several departments at ÅAU and
University of Turku co-operate on topics such as cancer, regenerative
medicine, inflammation and cardiovascular disease with close links to
health care and industry.
Åbo Akademi University is working for equal gender distribution and diversity in all staff categories.