Ajankohtaista

Cancer Cell Biology group at the University of Helsinki is seeking outstanding candidates for postdoctoral researcher

2.4.2019 | Avoimet työpaikat

The Faculty of Medicine promotes scientific research of a high standard and is responsible for providing research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, as well as for the English-language Master’s Programme in Translational Medicine. In addition to its teaching and research activities, the Faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. In terms of research, the Faculty aims for a place among the best medical faculties in the world, while consolidating and strengthening its status as a top-level institution of medical education.

Together with the Helsinki University Hospital (HUS) and the Helsinki Institute of Life Sciences (HiLIFE), the Faculty of Medicine, University of Helsinki, constitutes the Academic Medical Center Helsinki (AMCH). This medical center has been very successful in international comparisons, ranking among the top 10 medical campuses in Europe and among the top 50 globally.

Research Programs Unit of the Faculty of Medicine is a top-quality research environment. Unit’s nine research programs comprises groups that integrate clinical, translational and biomedical research.

Cancer Cell Biology group led by Professor Päivi Ojala (https://www.helsinki.fi/en/researchgroups/cancer-cell-biology) at the Translational Cancer Medicine Research Program (CAN-PRO), Faculty of Medicine, University of Helsinki, is seeking outstanding candidates for 

POSTDOCTORAL RESEARCHER

The open positions are in the fields of cancer cell biology and/or virus-host interactions in a project funded by Academy of Finland.

Our research is focused to study the role of lymphatic endothelium in the tumor microenvironment and cancer metastasis. We are interested in the changes in the tumorigenic properties of the cancer cells upon contact with the lymphatic endothelium, (Pekkonen et al, eLife 2018; PMID:29712618) and also in the changes induced in the lymphatics by the tumor cells. In the virus-host interaction studies we are using Kaposi sarcoma herpesvirus (KSHV), an oncogenic human gamma-2 herpesvirus, as a model system to study cancer development and progression (Gramolelli et al, Sci Rep 2018; PMID:29934628). Ultimately, our studies aim to provide mechanistic insights into both improving existing clinical regimens and in identifying novels targets for therapeutic intervention.

We are looking for highly motivated post-doctoral fellows who have successfully completed a PhD in a field relevant to the molecular and cellular biology of cancer and/or virology and published at least one peer-reviewed article in a Pubmed-indexed journal. Experience in mammalian cell culture, cell and molecular biology, as well as microscopy techniques are required. Candidates with demonstrated skills and prior experience in the analysis of NGS datasets and/or mouse tumor models as well as proven track record in terms of publications will be given preference.

Initial contract of employment will be done until the end of 2020 and starting as soon as possible. The contract of employment includes a probationary period of 6 months. Salary will be based on the Universities salary scheme for teaching and research personnel composed of both task specific and personal performance components. 

The application should be in form of a single-pdf containing a one-page cover letter describing your areas of expertise and motivation for the position, recent CV with a publication list, and names and contact information of two to three references.

The application, together with the required attachments, must be submitted through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) must submit their applications through the SAP HR portal.

Application at https://www.helsinki.fi/fi/avoimet-tyopaikat/postdoctoral-researcher . Apply at latest 10.04.2019.

Further information is available from Professor Päivi Ojala: paivi.ojala(at)helsinki.fi.

Postdoctoral Researcher in Vascular/Cancer Biology at the University of Helsinki

2.4.2019 | Avoimet työpaikat

The University of Helsinki is an international scientific community of 40,000 students and researchers, and ranks among the top 100 international universities in the world.

Research Programs Unit (RPU) of the Faculty of Medicine, University of Helsinki (https://www.helsinki.fi/en/faculty-of-medicine/research-programs-unit) consolidates demonstrated research excellence, with nine focused research programs combining clinical, translational and biomedical research. 

The group of Associate Professor Pipsa Saharinen works on the molecular and cellular mechanisms that regulate blood vessel functions during inflammation and in cancer (www.helsinki.fi/saharinenlab). A special focus is on the dynamic regulation of vascular permeability by angiopoietin growth factor, cytokine and integrin adhesion receptor signalling. The group is funded by the European Research Council (ERC) and belongs to the Academy of Finland Centre of Excellence in Translational Cancer Biology. 

The Saharinen group is currently seeking for a

POSTDOCTORAL RESEARCHER  

for a fixed-term starting as soon as possible, upon mutual agreement.

Highly motivated individuals with a commitment to excellence and with the capability to work independently and as a part of a dynamic and collaborative research group are encouraged to apply. A PhD degree in Life or Biomedical sciences, or an MD PhD degree, as well as excellent communication skills in spoken and written English, are required. Strong background in vascular/cancer biology, imaging, mouse genetics, or cell/molecular biology is an advantage.

We offer an international, inspiring and supportive research environment, excellent research facilities with access to state-of-the art technologies and a competitive salary, which is comprised of two separate parts; the job requirement component (here, level 5) and the personal performance component based on previous qualifications, experience and personal work performance, as per defined in the General Collective Agreement for Finnish Universities. A six-month trial period will be applied.

The application should include the following documents as a single pdf-file: a cover letter describing previous achievements and motivation for the position (1 page), CV, track record of peer-reviewed publications, and names and contact details of two to three referees. To apply, please, go to

https://www.helsinki.fi/en/open-positions/postdoctoral-researcher-position

Apply by 15.4.2019. The position will be filled once a suitable candidate has been identified. Further information is available from Pipsa.Saharinen(a)Helsinki.fi, tel. +358-50-4486361.

Recent publications:

Hakanpaa et al., Targeting beta1-integrin inhibits vascular leakage in endotoxemia. Proc Natl Acad Sci USA. 115:E6467-E6476, 2018. 

Korhonen E, Lampinen A et al. Tie1 controls angiopoietin function in vascular remodeling and inflammation. J Clin Invest. 126: 3495-3510, 2016.

Hakanpaa et al. Endothelial destabilization by angiopoietin-2 via integrin β1 activation. Nature Commun 6: 5962, 2015.

Saharinen et al., Therapeutic targeting of the angiopoietin–TIE pathway. Nat. Rev. Drug. Disc. 16:635-661, 2017.

Eklund L, Kangas J, Saharinen P. Angiopoietin-Tie signaling in the cardiovascular and lymphatic systems. Clin. Science. 1:87-103, 2017. 

Suomen Solubiologit ry:n vuosikokous Jyväskylän yliopistolla, Bio- ja ympäristötieteiden laitoksella 15.3.2019

30.3.2019 | Ajankohtaista

Suomen Solubiologit ry sai vuosikokouksessaan uuden hallituksen vuodelle 2019:

Elina Siljamäki (Puheenjohtaja)
Jan Koski (Varapuheenjohtaja)
Anne-Mari Koivisto (Sihteeri)
Johanna Matilainen (Tiedotussihteeri)
Linda Kauppinen (Rahastonhoitaja)
Eveliina Korhonen (Hallituksen jäsen)
Jenni Tuominen (Hallituksen jäsen)
Emilia Kettunen (Hallituksen jäsen)
Niko Kangasniemi (Hallituksen jäsen)


Haluamme vielä kerran kiittää Kari Salokasta kuluneista hallitusvuosista sekä toivottaa tervetulleeksi uuden hallituksemme jäsenen, Niko Kangasniemen!



”Hei vaan hei! Olen juuri valmistumaisillani filosofian maisteriksi solu- ja molekyylibiologian opintosuunnasta Jyväskylän yliopistosta. Erityisiin mielenkiinnon kohteisiini biologian alalla kuuluvat mikroskopia ja neurotieteen sovellukset! Toivonkin valmistumisen jälkeen voivani siirtyä väitöskirjahommiin näiden aiheiden parissa.” – Niko Kangasniemi, Suomen Solubiologit ry:n hallituksen uusi jäsen


Kokouksessa suunniteltiin muun muassa syksyllä järjestettävää työelämäseminaaria. Luvassa on myös jotain täysin uutta niin Solubiologi-lehden kuin tapahtumienkin osalta, joten pysykäähän kuulolla!

PhD Position (drug disposition and kinetics, NanoSIMS imaging) – AstraZeneca, Gothenburg, Västra Götaland County, Sweden

30.3.2019 | Avoimet työpaikat

https://job-search.astrazeneca.com/job/gothenburg/phd-position-drug-disposition-and-kinetics-nanosims-imaging/7684/11340707

Location: Gothenburg, Västra Götaland County, Sweden Job reference: R-047805
Posted date: Mar. 27, 201

Are you interested in imaging the inner structure of single cells to understand how drug molecules reach their subcellular targets? Would you like to contribute to the establishment of new technologies to study drug disposition/kinetics in cells and tissues by doing your PhD at AstraZeneca, a company that is following the science and turning ideas into life changing medicines? Then you might be the one we are looking for!

AstraZeneca is now recruiting an Industrial PhD student to join theDrug Metabolism Pharmacokinetics (DMPK) New Modalities function within the Cardiovascular, Renal and Metabolism (CVRM) therapy area. CVRM is intensely pursing new drug modalities (e.g peptides, proteolysis targeting chimera “PROTACs”, RNA based therapeutics). Building an understanding about subcellular trafficking presents a real opportunity for the development of biopharmaceuticals where we will design molecules that effectively navigate these pathways to reach their targets.  This PhD project will be done as part of the University of Gothenburg Chemical Imaging Infrastructure (CII)under the direction of Andrew G. Ewing. The successful candidate will be employed by AstraZeneca, and work collaboratively within the CII located at the AZ BioVentureHub, Gothenburg, Sweden.

The PhD project

In the pursuit of applying new drug modalities we are finding that intracellular target engagement is of critical importance. Thus, information concerning intracellular drug concentrations is greatly needed. However, this information is difficult to obtain, and it has been suggested that this space is one of the most neglected areas of drug discovery. AstraZeneca, in association with the CII, has now begun to integrate Nanoscale secondary ion mass spectrometry (NanoSIMS) imaging into the suite of technologies to study drug disposition/kinetics in cells and tissues.

This project is a Stiftelsen för Strategisk Forskning (SSF) funded industrial PhD position with the aim of developing a single cell analytical nano-imaging technique to provide subcellular drug distribution imaging with high sensitivity. It aims to combine advanced analytical technologies to solve fundamental biological questions of intracellular drug trafficking, to study and quantify endosomal escape and concentration of drug at disease targets inside the cell. You will develop the ability to bridge the physical aspects of ion/matter interactions and the biological process under investigation. In addition to course work and basic training for the PhD, you will develop scientific concepts and communicate the results of your research verbally and in writing. The position includes teaching (laboratory or tutorial) at the undergraduate level or performing other duties corresponding up to 20 per cent of working hours. Your major responsibilities will be to pursue your own doctoral studies.

About the CII

The Chemical Imaging Infrastructure (CII) is a world-unique research infrastructure with a primary focus on high lateral resolution imaging mass spectrometry. Internationally CII has a world leading equipment base backed up by internationally recognized experts in the development and application of SIMS. CII is hosted by the Department of Chemistry and Chemical Engineering at Chalmers and by the Department of Chemistry and Molecular Biology at the University of Gothenburg.

Requirements

  • To qualify as a PhD student, you must hold a Master’s level degree in BioScience, Biochemical Engineering, Biotechnology, Biochemistry, Chemistry or a similar area.
  • A strong interest in biology is required and experience with cell culture an advantage. Experience with mass spectrometry and image analysis is preferred but not required.
  • Excellent English in writing and speaking and strong communication skills are required.
  • Due to the multi-disciplinary nature of this PhD project, you should preferably be curious, goal oriented, cooperation minded, and keen on transferring theoretic and applied academic work into practice.

If you are interested, apply now!

For more information please contact recruiting manager Michael Kurczy michael.kurczy@astrazeneca.com or academic supervisor Andrew Ewing andrew.ewing@gu.se

Welcome with your application no later than April 21, 2019.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Postdoctoral Researcher or Early Stage Researcher (PhD student), evolutionary biology, reproductive physiology and molecular biology – University of Eastern Finland

25.3.2019 | Avoimet työpaikat

The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,000 students and 2,500 members of staff. We operate on two campuses in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.

The Faculty of Science and Forestry operates on the Kuopio and Joensuu campuses of the University of Eastern Finland. The mission of the faculty is to carry out internationally recognised scientific research and to offer research-education in the fields of natural sciences and forest sciences. The faculty invests in all of the strategic research areas of the university. The faculty’s environments for research and learning are international, modern and multidisciplinary.  The faculty has approximately 3,800 Bachelor’s and Master’s degree students and some 490 postgraduate students. The number of staff amounts to 560. http://www.uef.fi/en/lumet/etusivu

We are now inviting applications for a Postdoctoral Researcher or an Early Stage Researcher (PhD student) (evolutionary biology, reproductive physiology and molecular biology) position, Department of Environmental and Biological Sciences, Joensuu and/or Kuopio Campus

The application needs to be submitted no later than 30.4.2019 (by 24.00 hours Finnish time).

More information and application at http://www.uef.fi/en/uef/en-open-positions

PhD student position in Synthetic Biology for Improved Cell Factories – University of Oulu

25.3.2019 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/1181083988/?recommendedFlavor=HIDDEN_GEM&refId=d6325664-887e-4a81-9ff2-1945f6c9e4eb&trk=eml-jymbii-organic-job-card&midToken=AQFgumZyIt6sOQ&trkEmail=eml-jobs_jymbii_digest-null-3-null-null-41f64x%7Ejtkiqwnk%7Em9-null-jobs%7Eview

PhD student position in Synthetic Biology for Improved Cell Factories

The SECRETERS Marie Sklodowska Curie Innovative Training Network aims to develop “ A new generation of microbial expression hosts and tools for the production of biotherapeutics and high-value enzymes ”. The project will involve extensive collaborations between 6 academic and 5 industrial participants, who are based in 6 European countries.

The SECRETERS partnership aims to bring about a step change in the production of recombinant proteins, particularly Biotherapeutics and Industrial Enzymes. Both are critical products for the EU biotechnology sector, with combined markets in excess of $140 billion p.a.; the former are essential for the treatment of major diseases whereas the latter permeate every aspect of our daily life. Many proteins in these categories pose severe problems in production, especially disulfide-bonded proteins and new format ’difficult-to-express’ proteins. SECRETERS will train a team of 15 early stage researchers (ESRs) to develop a new generation of super-producing microbial production hosts, including Escherichia coli , Bacillus species and the yeast Pichia pastoris . The project capitalizes on a series of recent innovations and involves close collaboration between 6 academic Beneficiaries, who provide world-leading expertise in redox chemistry, synthetic biology and protein expression, and 5 non-academic Beneficiaries, who include some of the world’s premier biotherapeutic and industrial enzyme companies. It will enable the biotherapeutics industry to produce challenging medicines at lower costs, resulting in new drugs and wider patient access, and allow the enzymes industry to deliver a range of powerful new products. Based on a responsible innovation approach, with clear foci on research and entrepreneurial training, SECRETERS will deliver a team of superbly-trained scientists, poised to engage in some of Europe’s most important biotechnology sectors.

We Offer

An open PhD student position is available in the field of synthetic biology for improved cell factories in the research group of Prof Lloyd Ruddock (http://www.oulu.fi/biocenter/groups/ruddock). The appointed PhD student will work within the SECRETERS ITN on developing improved systems for catalyzed disulfide bond formation in the cytoplasm of E.coli .

The University of Oulu in Northern Finland, is an international, multidisciplinary research university with a rich pool of creative and intellectual talent. The strengths of the University include broad, multidisciplinary research interests, a modern research and study environment, and wide cooperation with international research and educational institutes (

The position is located at the Faculty of Biochemistry and Molecular Medicine (FBMM) (

Description Of The Project

The project is aimed at the development of new ways to produce disulfide-bonded proteins in the E.coli cytoplasm using CyDisCo technology. 2 nd generation CyDisCo components will be developed to improve on the already high levels of target protein production, with a special focus on the generation of high yields of complex proteins with large numbers of disulfide bonds. Quantitative data on expression levels of disulfide-bonded proteins in E.coli will be generated for modelling by other ESRs in the consortium.

The ESR will participate in an extensive training programme, including secondments to industrial partners in the consortium.

The position is a fixed MCA actions ESR fellowship. This position is for 36 months . The salary will be around 3000 €/month, depending on experience. According to the ITN rules a mobility allowance and, if eligible, family allowance are included. The starting date is Sept 1, 2019, or as soon as possible thereafter.

A six-month trial period will be effective in the beginning of a contract.

Required Qualifications And Assessment

Excellent applicants with degrees and/or expertise in biochemistry, biotechnology, molecular biology or systems biology are invited. The successful applicant must hold a MSc degree in one of these fields. Candidates who have completed required courses and whose MSc thesis will be submitted by May 1 st 2019 will also be eligible.

The applicant must fulfill the criteria for admission to UniOGS:

Fluent oral and written English skills as well as good communication and teamwork skills are required.

At the date of recruitment, applicants must be in the first four years of their career and not have a doctoral degree. They can be a national of any country, but must not have resided or carried out main activity (studies, work etc) in Finland for more than12 months in the 3 years immediately prior to the recruitment date.

Application Procedure

The following documents must be attached to the application (in English):

  • Curriculum vitae with the names and contact details of at least 2 referees
  • Brief description of research merits, experience and motivation
  • Copies of the MSc certificate and transcript

Applications, together with all relevant enclosures, must be submitted using the electronic application system by 30.3.2019 (link via

Selected candidates will initially be invited for an interview by Skype. Short-listed candidates will then be invited for a recruitment symposium in May 2019 in Groningen, the Netherlands, for which travel costs and accommodation will be reimbursed.

For Further Information Regarding The Filling Of This Post

Prof Lloyd Ruddock, group leader, email: lloyd.ruddock(at)oulu.fi

Tiina Hurskainen, HR manager, email: tiina.hurskainen(at)oulu.fi

Suomen Solubiologit ry:n 45-vuotisjuhlaseminaari 15.3.19 Jyväskylässä

21.3.2019 | Koulutukset / seminaarit

Suomen Solubiologit ry:n hallitus haluaa kiittää kaikkia Suomen Solubiologit 45-vuotisjuhlaseminaariin osallistuneita kävijöitä, puhujia ja näytteilleasettajia! Paikan päällä saadun palautteen perusteella juhlaseminaarimme oli erittäin onnistunut, ja väkeäkin oli oikein mukavasti. Yhdistyksemme sai 45v onnittelut myös Akavan Etelä-Pohjanmaan puheenjohtajalta Kari Hongistolta, jonka terveiset luettiin seminaarimme alussa. Päivämme alkoi yhdistyksen vuosikokouksella, minkä jälkeen seurasi varsinainen juhlaseminaari. Seminaarin aikana saimme kuulla esitykset Eva-Mari Arolta (akateemikko, professori), Howy Jacobsilta (professori), Eeva-Liisa Eskeliseltä (professori), Jyrki Heinolta (professori), Markku Kallajoelta (dosentti, patologi) ja Markku Kulomaalta (emeritusprofessori). Päivä huipentui cocktailtilaisuuteen, jonka aikana nautimme hyvästä ruoasta ja seurasta. Lisäksi Jari Rantamäelle myönnettiin yhdistyksen kunniajäsenyys, ja seminaarikävijät pääsivät kisaamaan Kahoot! tietovisan merkeissä. Tästä on hyvä jatkaa työtä solubiologien hyväksi!


Postdoctoral Researcher, Bioinformatics, Toxicogenomics and Machine Learning – University of Eastern Finland, Institute of Biomedicine

21.3.2019 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?id=00007118&did=5600&lang=en&jc=16&nav_from_open_jobs_view_new=true

The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 2 500 degree students and about 450 PhD students in the Faculty. The faculty has 680 staff members. http://www.uef.fi/en/ttdk/etusivu
We are now inviting applications for

a Postdoctoral Researcher (Bioinformatics, Toxicogenomics and Machine Learning) position, School of Medicine, Institute of Biomedicine, Kuopio Campus.

The position is available in the Biomedical Informatics research group (http://www.uef.fi/web/biomedicine/biomedicalinformatics) led by Dr Vittorio Fortino, in the recently launched EU H2020 project EDCMET.

The project is focused on the development of computational methods to identify endocrine disrupting effects of chemicals. This work will employ bioinformatics and cheminformatics methodologies, toxicology and toxicogenomic databases, data mining and machine learning to; (a) predict the overall biological phenotype emerging from a chemical exposure (e.g. adaptive versus adverse); and, (b) to identify suitable biomarkers for chemical exposure and effect.

The ideal candidate will have a strong background in omics data analysis, with experience in data mining and machine learning methods applied to toxicogenomics and/or toxicology data. She or he will have an inquisitive mindset, a proactive attitude and the desire to work in a multi-disciplinary team. She or he will join a vibrant scientific community and collaborate with other scientists across disciplines, including molecular biology, systems biology, data science and translational medicine.

A person to be appointed as a postdoctoral researcher shall hold a suitable doctoral degree. Positions of postdoctoral researchers shall always be filled for a fixed term (UEF University Regulations, Section 31).

The person to be appointed to the Postdoctoral Researcher Position is required to hold a doctoral degree, which may not have been completed more than five years ago at the time of accepting the position. In this context, the 5 years refer to a net period of time, which does not include maternity leaves, parental leaves, or military service, etc.

The language requirements associated with the position are defined in the Government Decree 770/2009. Members of the university’s teaching and research staff are required to have command of the language they give teaching in (Finnish or Swedish). The Dean of the faculty may grant an exemption from the language proficiency requirements laid down in the Government Decree.

Other qualification requirements/ prerequisites

  • A strong track record in omics data analysis (e.g. genome-wide, rna-seq and proteomics data analysis).
  • Proficient in programming in R or Python, basic knowledge of statistical modelling and data mining, and ability to query databases and handle large data sets.
  • Experience in using toxicology and toxicogenomic databases is a plus.
  • Excellent analytical, communication and organizational skills.
  • Demonstrated capability as highly organized, a creative problem-solver, self-motivated and able to work independently as well as within cross-functional teams. 
  • Fluency in written and spoken English

The position is initially filled for a fixed-term of three years. The full-time position will start in June 2019, or later by agreement.
The salary of the position is determined in accordance with the salary system of Finnish universities and is based on level 5 of the job requirement level chart for teaching and research staff (€2,935,55/ month). In addition to the job requirement component, the salary includes a personal performance component, which may be a maximum of 50 % of the job requirement component.

For further information on the position, please contact: Assistant Professor Vittorio Fortino, email: vittorio.fortino@uef.fi, phone +358 29 4454197. For further information on the application procedure, please contact HR Secretary Tellervo Rajanto, email: tellervo.rajanto@uef.fi, phone +358 29 4454278.  

A probationary period is applied to all new members of the staff.

The electronic application should contain the following appendices:
a résumé or CV
a list of publications
– motivation letter
– copies of the applicant’s academic degree certificates/ diplomas, and copies of certificates / diplomas relating to the applicant’s language proficiency, if not indicated in the academic degree certificates/diplomas 

The application needs to be submitted no later than 8.4.2019 (by 24.00 hours Finnish time) by using the electronic application form.

Early Stage Researcher, Bioinformatics /Omics Data Analytics and Machine Learning) position – University of Eastern Finland, Institute of Biomedicine

21.3.2019 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/application_edit_welcome.html?field_id=0&job_name=Early+Stage+Researcher%2C+Bioinformatics+%2FOmics+Data+Analytics+and+Machine+Learning%29+position&job_id=7081&jc=16&lang=en&place_id=187&did=5600

The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 2 500 degree students and about 450 PhD students in the Faculty. The faculty has 680 staff members. http://www.uef.fi/en/ttdk/etusivu

We are now inviting applications for

an Early Stage Researcher (Bioinformatics / Omics Data Analytics and Machine Learning) position, School of Medicine, Institute of Biomedicine, Kuopio Campus

The position is available in the Biomedical Informatics research group (http://www.uef.fi/web/biomedicine/biomedicalinformatics) led by Dr Vittorio Fortino, in the recently launched EU H2020 project BIOMAP.

The project is focused on the analysis of multi-omics data for identifying and targeting personalized treatments in two common chronic skin diseases: atopic dermatitis (AD) and psoriasis (Pso). The aim of the project is to develop novel computational methods and tools for multi-omics data modelling and the definition of disease subtypes and predictive biomarkers. The topics of the research projects will be discussed in more detail during the interview of the selected candidates.

A person to be appointed as an early stage researcher shall be qualified to pursue postgraduate studies, i.e. he or she is required to have completed a suitable higher university degree or an equivalent education abroad which in the country in question would qualify the person for similar academic studies. Positions of early stage researchers shall always be filled for a fixed term (UEF University Regulations, Section 31).

Good command of the English language is required. The language requirements associated with the position are defined in the Government Decree 770/2009. Members of the university’s teaching and research staff are required to have command of the language they give teaching in (Finnish or Swedish). The Dean of the faculty may grant an exemption from the language proficiency requirements laid down in the Government Decree.

Applicants with a background in molecular biology and bioinformatics analysis of next-generation sequencing and microarray data are encouraged to apply. Persons graduating in the near future are also encouraged to apply. However, they are expected to hold a relevant MSc degree (or equivalent) by the starting date of the early stage researcher position. A successful candidate will have good command of the English language and good skills in data analysis and programming, specifically experience in R/Python and Linux is highly desired.

The position is initially filled for a fixed-term of two years. The full-time position will start in May 2019, or later by agreement.

The salary of the position is determined in accordance with the salary system of Finnish universities and is based on levels 2-4 of the job requirement level chart for teaching and research staff (€2,033,29 – 2,535,20/month). In addition to the job requirement component, the salary includes a personal performance component, which may be a maximum of 50 % of the job requirement component.

For further information on the position, please contact:
 Dr Vittorio Fortino, email: vittorio.fortino@uef.fi, phone +358 29 4454197. For further information on the application procedure, please contact HR Secretary Tellervo Rajanto, email: tellervo.rajanto@uef.fi, phone +358 29 4454278.  
A probationary period is applied to all new members of the staff.

The electronic application should contain the following appendices:
a résumé or CV
a list of publications
– motivation letter
– copies of the applicant’s academic degree certificates/ diplomas, and copies of certificates / diplomas relating to the applicant’s language proficiency, if not indicated in the academic degree certificates/diplomas

The application needs to be submitted no later than 1.4.2019 (by 24.00 hours Finnish time) by using the electronic application form.

Tutkijatohtori/nuorempi tutkija (evoluutiobiologia, lisääntymisfysiologia ja molekyylibiologia) – Itä-Suomen yliopisto, Ympäristö- ja Biotieteiden laitos

21.3.2019 | Avoimet työpaikat

https://rekry.saima.fi/certiahome/open_job_view.html?id=00007129&did=5600&lang=fi&jc=16&nav_from_open_jobs_view_new=true

Itä-Suomen yliopisto on yksi Suomen suurimmista monialaisista tiedeyliopistoista. Tarjoamme opetusta lähes sadassa pääaineessa. Opiskelijoita on noin 15 000 ja työllistämme 2 500 henkilöä. Toimimme kahdella kampuksella Joensuussa ja Kuopiossa. Kansainvälisissä yliopistojen vertailuissa sijoitumme maailman parhaiden joukkoon.

Luonnontieteiden ja metsätieteiden tiedekunta toimii Itä-Suomen yliopiston Kuopion ja Joensuun kampuksilla. Tiedekunnan tehtävänä on harjoittaa korkeatasoista kansainvälistä tieteellistä tutkimusta ja tarjota siihen perustuvaa yliopistollista koulutusta luonnontieteiden ja metsätieteiden alalla. Tiedekunta panostaa yliopiston strategian mukaisiin tutkimusalueisiin. Tiedekunnan tutkimus- ja oppimisympäristöt ovat kansainvälisiä, moderneja ja monitieteisiä. Tiedekunnassa on noin 3 800 perustutkinto-opiskelijaa ja 490 jatko-opiskelijaa. Henkilöstömäärä on noin 560. http://www.uef.fi/fi/lumet/

Haettavana on

Tutkijatohtorin tai nuoremman tutkijan (evoluutiobiologia, lisääntymisfysiologia ja molekyylibiologia) tehtävä, Ympäristö- ja Biotieteiden laitos (Joensuun ja/tai Kuopion kampus)

Haemme motivoitunutta määräaikaista tutkijatohtoria/nuorempaa tutkijaa (jatko-opiskelijaa) Suomen Akatemian rahoittamaan hankkeeseen ”Ihmisen sukusolujen yhteensopivuuden molekulaarinen ja immunologinen perusta”, https://reprophys.weebly.com/ Hankkeen tavoitteena on selventää naisen lisääntymiselimistössä tapahtuvan siittiöiden valinnan (’cryptic female choice’), hedelmöittymisen sekä hedelmättömyyden molekyylibiologisia ja immunologisia mekanismeja. Vaikka hedelmöittymisen mekanismeja on tutkittu jo yli 100 vuoden ajan, hedelmöittymisprosessi on edelleen yksi heikoimmin tunnetuista biologisista tapahtumista. Tämä rajoittaa paitsi lisääntymisen ja lisääntymisongelmien, myös evoluution ja perinnöllisyyden mekanismien ymmärtämistä.

Palkattavan tutkijan tehtävänä on osallistua näitä mekanismeja havainnollistavaan kokeelliseen tutkimukseen ihmisellä. Riippuen valittavan henkilön kokemuksesta, työtehtäviin voi kuulua mm. molekyylibiologiset (mm. uuden sukupolven sekvensointi) ja immunogeneettiset (mm. Human Leucocyte Antigen) analyysit, siittiöiden liikkuvuus- ja kemotaksiatutkimukset sekä naisen lisääntymiselimistön ja erilaisten ympäristöaltisteiden indusoimien siittiöiden fysiologisten muutosten mittaaminen. Erityisesti toivomme hakemuksia uuden sukupolven sekvensointiaineiston bioinformaattisten analyysien osaajilta. Työtehtäviin kuuluu myös kerätyn aineiston analysointi ja raportointi tieteellisissä julkaisusarjoissa.

Hakijalta edellytetään hyvää englannin kielen kirjallista ja suullista taitoa. Aiempi kokemus laboratoriotyöskentelystä, molekyylibiologisista (esim. RNA-seq analyysit ja bioinformatiikka) ja/tai solubiologista (esim. virtaussytometria ja ELISA analyysit) menetelmistä katsotaan eduksi hakijalle. Jos sinulla on jokin näistä taidoista, pyydämme kertomaan siitä ansioluettelossa ja/tai motivaatiokirjeessä (ks. alla).

Tutkijatohtorilta edellytetään soveltuva tohtorin tutkinto, joka on suoritettu enintään 5 vuotta ennen tutkijatohtorin tehtävän vastaanottamista. Mikäli tohtorin tutkinto on suoritettu yli 5 vuotta ennen tehtävän aloittamista, hänet otetaan projektitutkijan tehtävään. Aikaraja tarkoittaa tässä yhteydessä nettoaikaa, johon ei lasketa esim. äitiys- tai vanhempainlomaa tai asevelvollisuuden suorittamista.

Projektissa on mahdollisuus tehdä myös väitöskirjatyö, jolloin nimikkeenä on nuorempi tutkija. Nuoremman tutkijan tulee olla jatkokoulutuskelpoinen, soveltuvan ylemmän yliopistotutkinnon suorittanut tai soveltuvan ulkomaisen koulutuksen, joka asianomaisessa maassa antaa kelpoisuuden vastaaviin korkeakouluopintoihin, suorittanut.

Tehtävään mahdollisesti kuuluva opetus ja ohjaus voidaan toteuttaa englannin kielellä.  

Tehtävä täytetään alustavasti ajalle 1.7.2019-31.8.2020. Mahdollisesta jatkosta sovitaan lisärahoituksen varmistuttua. 

Määräaikaisuuden perusteena on neliportaisen uramallin mukainen opetus- ja tutkimustehtävä ja määräaikainen hanketehtävä. (Tutkijatohtorin/nuoremman tutkijan tehtävään otetaan aina määräajaksi, johtosääntö 31§).

Tutkijatohtorin tehtävän palkkaus määräytyy yliopistojen opetus- ja tutkimushenkilöstön palkkausjärjestelmän mukaisesti vaativuustasolle 5 (2 935,55 €/kk). Nuoremman tutkijan tehtävän palkkaus määräytyy palkkausjärjestelmän mukaisesti vaativuustasoille 2-4 (€2033,29 – €2535,20/ kk). Tehtäväkohtaisen palkanosan lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on enintään 50 % tehtäväkohtaisesta palkanosasta.

Lisätietoja tehtävän osalta antaa: Akatemiatutkija Jukka Kekäläinen, sähköposti: jukka.s.kekalainen[a]uef.fi, puh. +358 50 467 4487 ja hakumenettelyn osalta: Henkilöstösihteeri Noora Hämäläinen, sähköposti: noora.hamalainen[a]uef.fi, puh. +358 50 409 0376

Uuden työntekijän tullessa yliopiston palvelukseen käytetään koeaikaa.

Sähköiseen hakemukseen tulee liittää:

Ansioluettelo
Julkaisuluettelo
– Kopiot tutkintotodistuksista ja kielitaitoa osoittavista todistuksista, ellei kielitaito ilmene tutkintotodistuksista
– Motivaatiokirje (englanninkielinen, enintään 2 sivua). Kerro kirjeessä, miksi tutkimusaihe kiinnostaa sinua ja miksi olisit sopiva henkilö tehtävään

Hakemus tulee jättää viimeistään 30.4.2019 sähköisellä hakulomakkeella.

Hakemuksen voit jättää klikkaamalla alla olevaa linkkiä ”täytä hakemus”.