11.10.2018 | Ajankohtaista
The successful candidate will join a multidisciplinary research program to participate in internationally-recognized, NIH-funded, translational alcohol dependence neuroscience research. The postdoctoral candidate will receive the theoretical and technical training to engage in preclinical experimentation that integrates behavioral animal models (encompassing motivational, negative affective and cognitive control domains) with state-of-the-art neuroscientific techniques, from gene to behavior, to elucidate neuroadaptations in limbic and cortical systems that promote maladaptive behavioral regulation in alcohol dependence and neuropsychiatric disorders.
Highly motivated candidates with a strong work ethic and published experience using pharmacological, immunohistochemical, molecular or genetic/epigenetic approaches to understand and/or modify behavior are urged to apply.
The Laboratory of Alcoholism and Addictions Neuroscience is one of many labs comprising the Alcohol and Drug Abuse Research Program and the Translational Addiction Research Center which collectively provide a wealth of intellectual resources to support a vibrant research environment at Washington State University. The candidate must have a Ph.D. in a biological psychology- or neuroscience-related discipline and be capable of successfully working with others, supervising trainees, independently conducting experiments, analyzing data, writing manuscripts and disseminating research findings. Inquiries about this position can be addressed by contacting the Principle Investigator (Brendan Walker; b_walker(at)wsu.edu).
If interested in applying for this opportunity, please submit a curriculum vitae, a brief statement of research interests and contact information for three recommenders to b_walker(at)wsu.edu by 11/15/2018. Starting salary will be according to NIH recommended guidelines for years of postdoctoral research experience. This position is located in the heart of Washington’s beautiful ‘Palouse’ region in the architectural award winning Veterinary and Biomedical Research Building on the Pullman campus of Washington State University.
11.10.2018 | Ajankohtaista
Open postdoctoral researcher position (synthetic biology, antibody technology, antibody drug development)
We are looking for a postdoctoral researcher to join our team in the field of molecular & cellular biology/biochemistry. Project goals include improvements of in-vitro antibody generation technologies and the generation of antibodies. Details will be discussed in the job interview. The project involves the setup of novel methods and requires knowledge and experience in the areas of molecular biology (cloning, mutagenesis), E. coli genetics, protein analysis (Western, IP, ELISA), protein purification (basics) and cell culture (transfection, cell line establishment). Knowledge in bioinformatics will be advantageous. Nine months postdoctoral position with possible extension starts in January/February 2019. The salary is based on the standard University of Helsinki salary system.
How to apply?
If you are interested, please send your application including CV, motivation letter and names of two people who would be willing to provide references with contact information as a single pdf-document to michael@jeltsch.org with a notification ”Postdoc position” in the subject line of the mail. Please also attach or link to a short (maximally 2 minutes long) video, in which you explain, why you want to join our lab and why you are the candidate that we should chose. Please follow these instructions, as I do not guarantee to answer applications that do not fulfil these formal requirements.
10.10.2018 | Ajankohtaista
The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.
The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 2 500 degree students and about 450 PhD students in the Faculty. The faculty has 680 staff members. http://www.uef.fi/en/ttdk/etusivu
We are now inviting applications for
a Postdoctoral Researcher/Project Researcher (Cell Biology) position, School of Medicine, Institute of Biomedicine, Kuopio Campus
The position will be based in the project “Focus on the basic biology of extracellular vesicles”, led by Kirsi Rilla and granted by Jane and Aatos Erkko Foundation.
The project is focused on solving the mechanisms of extracellular vesicles (EV) biogenesis, their interactions with target cells and extracellular matrix. The aim of the project is to develop novel bioimaging methods for detection and analysis of EVs. Methods to be used during the project include, e.g., 2D and 3D cell cultures, electron and confocal microscopy, Western blot and flow cytometry. Testing and development of novel methods for EV isolation and analysis is also an essential aim of this project.
A person to be appointed as a postdoctoral researcher shall hold a suitable doctoral degree. Positions of postdoctoral researchers shall always be filled for a fixed term (UEF University Regulations, Section 31). If the doctoral degree has been awarded more than five years ago, the post will be one of a Project Researcher.
The person to be appointed to the Postdoctoral Researcher position is required to hold a doctoral degree, which may not have been completed more than five years ago at the time of accepting the position. In this context, the 5 years refer to a net period of time, which does not include maternity leaves, parental leaves, or military service, etc.
The language requirements associated with the position are defined in the Government Decree 770/2009. Members of the university’s teaching and research staff are required to have command of the language they give teaching in (Finnish or Swedish). The Dean of the faculty may grant an exemption from the language proficiency requirements laid down in the Government Decree.
A successful Postdoctoral/Project Researcher candidate has wide experience in cellular biology methods. Experience or special interest in biological imaging, imaging software and image analysis as well as in fluorescence applications are preferable. Experience in electron microscopy is considered an advantage. Previous experience in EV biology and analysis is also desired. Good knowledge of written and spoken English is essential. An ideal candidate will have a high degree of independence, motivation, enthusiasm and commitment. The position will include teaching in suitable areas, and the teaching language may be English.
The position is filled for a fixed term from 1.1.2019 to 31.12.2021 (or as agreed). The position is filled for a fixed-term due to the duration of the project.
The salary of the position is determined in accordance with the salary system of Finnish universities and is based on level 5 of the job requirement level chart for teaching and research staff (€2,893.95/ month). In addition to the job requirement component, the salary includes a personal performance component, which may be a maximum of 46.3% of the job requirement component.
For further information on the position, please contact: Kirsi Rilla, tel. +358 29 4454255, kirsi.rilla@uef.fi. For further information on the application procedure, please contact HR Secretary Tellervo Rajanto, tel. +358 29 445 4278, tellervo.rajanto@uef.fi
A probationary period is applied to all new members of the staff.
The electronic application should contain the following appendices:
– a résumé or CV (http://www.tenk.fi/en/template-researchers-curriculum-vitae)
– a list of publications (http://www.aka.fi/en/funding/how-to-apply/application-guidelines/guidelines-for-list-of-publications/guidelines-for-complete-list-of-publications/)
– copies of the applicant’s academic degree certificates/ diplomas, and copies of certificates / diplomas relating to the applicant’s language proficiency, if not indicated in the academic degree certificates/diplomas
– a motivation letter
– possible recommendation letters from previous and recent supervisors/Pls.
The application needs to be submitted no later than 31.10.2018 (by 24.00 hours Finnish time) by using the electronic application form.
1.10.2018 | Ajankohtaista
Sr. Research Associate 1 (PostDoc Fellow/ Assistant Scientist)
Our research focuses on the genetic/epigenetic mechanisms of neuropathic pain, and opioid abuse with gene therapy supported by the recent NIH funded projects. The positions open to recent PhD and/or MD with background in neuropharmacology, neuroscience, molecular biology, histology/imaging or a related discipline. Priority to applicants with skills of strong genetic/epigenetics, gene cloning, exosome, luciferase assay, DNA damage, is given.
Applicants with Master degree and strong background related to this research skill are also available.
Send your CV and the names of referees to:
Dr. Hao, Anesthesiology, U. of Miami, Miami, FL 33136
28.9.2018 | Ajankohtaista
http://www.kct.fi/we-are-looking-for-a-junior-scientist
Kuopio Center for Gene and Cell Therapy (KCT) is looking for a Junior Scientist for upstream (US) and downstream (DS) process development team.
KCT DS process development is focusing to improve the platforms and methods to concentrate and purify viral vectors. Typically Adeno-, Lenti- and AAV-viral vectors are produced in small lab scale bioreactors or in Pilot area for scale-up. Purification processes are performed typically in clarification filtration, Tangential flow filtration and in chromatography steps.
Junior Scientist would be responsible for taking care of the laboratory basic functions and to participate in DS process development with the team. The job requires know how on US and DS techniques such as bioreactors, TFF and chromo and the ability to operate equipment independently after adequate training. Suitable candidate has either an University degree or has obtained the needed skills through several years of work experience. Previous experience working with different filtration, TFF and chromatography systems is seen as an advantage. Analytical and upstream process development experience should also be useful. The nature of process development requires ability to cope with changing situations and a mindset willing to face and overcome challenges.
In addition to challenges we offer modern facilities, inspiring atmosphere and skillful team with good motivation. Our goal is to develop GMP ready processes for the future. Would you like to be part of it?
Find us from LinkedIn and Instagram!
Kindly send your cover letter and CV including your salary request to jobs@kct.fi by Oct 7th 2018.
Additional information on the job is given by Laboratory Manager Joonas Malinen tel.: +358456384809 and Gene Therapy Director Hanna Lesch tel.: +358505434900 on Fri Sep 28th and Fri Oct 5th at 13:00-14:00.
26.9.2018 | Ajankohtaista
A graduate student/postdoctoral fellow position in Developmental Neurobiology
Site of research: Molecular and Integrative Biosciences Research Program, Faculty of Biological and environmental Sciences, Viikki Biocenter, University of Helsinki
Title of the project: Brainstem neurons behind mood, memory and motivation – from development to behavioral control
Background and aim: Brainstem nuclei are critically important for regulation of mood, motivation and voluntary movements. Abnormal function of these neurons is involved in neuropsychiatric disorders, including depression, addiction, schizophrenia and Parkinson’s disease. Unlike the brainstem dopaminergic and serotonergic neurons, the other brainstem neurons, including inhibitory GABAergic neurons, are very poorly understood. Using techniques, such as single cell mRNA sequencing and gene modified mice, we have revealed a framework for development of the main brainstem GABAergic neuron groups.
Having identified the cell types, we can now address the following questions:
How are these brainstem GABAergic neuron subgroups incorporated into brain circuits?
How do they regulate mood, memory, motivation and movement?
An enthusiastic post-doctoral fellow/student can join our group to study these questions.
Funding: The project in funded by the Academy of Finland. The salary is based on the University of Helsinki salary scale.
Timing: The post-doctoral fellow contract until 31.8.2019, with possible extension.
Application details: Application should include a letter of motivation, CV with the list of publications and contact information of at least two persons for references. The dead-line for applications is October 22nd, 2018. Contact for inquiries and applications: Prof. Juha Partanen (Juha.M.Partanen@Helsinki.Fi), Molecular and Integrative Biosciences Research Program, Faculty of Biological and Environmental Sciences, 00014-University of Helsinki, Finland.
25.9.2018 | Ajankohtaista
Postdoctoral positions in the group of Pontus Aspenström at the Department of Immunology, Genetics and Pathology at Uppsala University (www.igp.uu.se ). The Department has a broad research profile with strong research groups focused on cancer, autoimmune and genetic diseases. A fundamental idea at the department is to stimulate translational research and thereby closer interactions between medical research and health care. Research is presently conducted in the following areas: medical and clinical genetics, clinical immunology, pathology, neuro-oncology, vascular biology, radiation science and molecular tools. Department activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Akademiska Sjukhuset, Uppsala.
Work description:
Out group is studying the Ras-like family of Rho GTPases, which are key regulators of the actin filament system and thereby control vital cellular processes such as cell morphogenesis, cell polarity and cell migration. The work in our group is aimed to elucidate the Rho-dependent signalling mechanisms in health and disease. There are currently two positions on scholarships available in our group:
1. The research studies on this project will focus on the Miro GTPases, which are key players in mitochondrial homeostasis and functioning. Their importance in a physiological context also makes them significant proteins in the pathology of neurodegenerative diseases. Both proteins are linked, either directly or via downstream signalling partners, to the disease progression of Alzheimer’s and Parkinson’s diseases. The overarching aim of this project is to enhance the understanding of the function of Miro GTPases in neurodegenerative diseases.
2. The second project will focus on the role of the atypical Rho GTPases in cancer. This family of proteins are pivotal regulators of tumour cell migration and deregulated activity of Rho GTPases is often associated to poor prognosis of certain types of cancers. We are studying the role of the atypical Rho GTPases, which is a subclass of the Rho GTPases, in malignant mesothelioma and glioblastoma. The principal goal is to elucidate the mechanisms behind the derailed function of atypical Rho GTPases in cancer cell migration and metastasis.
Qualifications:
We are seeking a highly motivated, talented and well-educated researcher with a PhD degree awarded within the past three years in cell biology, neuroscience or in a related research topic.
Scholarships for carrying out postdoctoral research may be granted to persons living in other countries who come to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education. Persons who are resident in Sweden and/or have carried out all or part of their academic education at an educational institution in Sweden cannot be considered for scholarships. The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish PhD or higher.
The application should include a CV, copies of diplomas including grades, publications and a short description of your research interests.
Merits:
The applicant should have a strong background in molecular cell biology and practical experience of standard cell biology techniques, including microscopy and imaging, is a prerequisite. Uppsala University values the qualities that even gender distribution and diversity add to the research environment. We therefore welcome applicants of any gender and with different birth background, functionality and life experience.
Application:
An application must contain the following documents in English:
1. Curriculum vitae and qualifications
2. A complete list of publications.
3. A summary of current research (no more than one page).
4. Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances.
5. Contact details for two reference persons.
The applications will be assessed based on eligibility requirements, achievements in related research areas, and personal suitability.
Scholarship:
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. This educational scholarship is tax-exempt.
The amount is set for twelve months at a time and is paid out on a monthly basis.
Start date: As soon as possible.
22.9.2018 | Ajankohtaista
Organisaation esittely
Lääkealan turvallisuus- ja kehittämiskeskus Fimea on sosiaali- ja terveysministeriön alainen virasto, joka valvoo ja kehittää lääkealaa väestön terveydeksi.
Tehtävän kuvaus
Erikoistutkijan pääasiallisena tehtävänä on biologisten lääkevalmisteiden laadun arviointi osana myyntilupahakemusten ja kliinisten lääketutkimusten kokonaisarviointia. Lisäksi tehtäviin sisältyy biologisiin lääkkeisiin liittyvää tieteellistä neuvontaa sekä kansallisella että EU tasolla ja toimijoiden ohjausta.
Avoinna olevaan virkaan ja vuoden mittaiseen määräaikaiseen virkasuhteeseen haetaan ensisijaisesti asiantuntijoita solubiologian ja biokemian osaamisalueilta.
Hakijalta odotamme
Tehtävien menestyksellinen hoitaminen edellyttää:
• Ylempää korkeakoulututkintoa ja tehtäväalueeseen soveltuvaa tieteellistä jatkokoulutusta tai kokemusta tieteellisestä tutkimustyöstä soveltuvilla aloilla (esim. biokemia, solubiologia, bioteknologia)
• Hyviä yhteistyö- ja vuorovaikutustaitoja
• Kykyä ja halua kotimaiseen ja EU-yhteistyöhön moniammatillisessa asiantuntijaorganisaatiossa
• Sujuva suomen- ja englannin kielen suullista ja kirjallista taitoa sekä tyydyttävää ruotsin kielen taitoa
Hakijalle katsotaan eduksi:
• Erityisosaaminen solubiologian alalta tai laaja-alainen asiantuntemus biokemian alueelta
• Kokemus soluvalmisteiden tai rekombinanttiproteiinien lääkekehityksestä ja/tai lääketuotannosta
• Käytännön kokemus rekombinanttiproteiinien karakterisointi-tutkimuksista sekä analyysimenetelmien validointitutkimuksista.
Työssä tarvittava kielitaito
Sujuva suomen- ja englannin kielen suullinen ja kirjallinen taito sekä tyydyttävä ruotsin kielen taito.
Tehtävän tiedot
Tehtävän kesto: Vakinainen
Työaika: Virastotyöaika
Tehtävä alkaa: 1.11.2018 Tai sopimuksen mukaan.
Virka on viraston yhteinen.
Tehtävän hakemista koskevat tiedot
Hae viimeistään: 28.9.2018 16:15
ID: 33-263-2018
Voit kuitenkin hakea tätä työpaikkaa myös toimittamalla hakemuksesi alla olevaan osoitteeseen. Sekä hakemuksessa että kirjekuoressa tulee mainita haettavan tehtävän ID. Hakemuksia ei palauteta.
Lääkealan turvallisuus- ja kehittämiskeskus/Kirjaamo
PL 55
00034 FIMEA
Palkkaukseen liittyvät tiedot
LAP –prosessin FBY-yksikön erikoistutkijan virka on sijoitettu vaativuusluokkaan 11a, jossa tehtäväkohtainen palkanosa on 4444,96 euroa/kk. Virassa maksetaan lisäksi henkilökohtaiseen työsuoritukseen perustuvaa palkanosaa, joka on enintään 42 % tehtävän mukaisesta palkasta.
Tehtävä
Ilmoitettujen työpaikkojen määrä: 2
vakituinen virka ja määräaikainen virkasuhde
Yhteystiedot
Lisätietoja tehtävästä
Niklas Ekman Jaostopäällikkö +358 29 522 3321
Marjo-Riitta Helle Yksikönpäällikkö +358 29 522 3320
Muut tehtävään liittyvät tiedot
Fimea toimii monipaikkaisena virastona. Fimean toimipaikat ovat Kuopiossa, Helsingissä, Tampereella ja Turussa. Viran sijoituspaikka voidaan sopia.
21.9.2018 | Ajankohtaista
Postdoctoral researcher in Molecular Systems Immunology and Computational Biomedicine Group at Turku Centre for Biotechnology
A position for a postdoctoral researcher working in Elo and Lahesmaa Laboratories is open for applications. We are looking for a highly motivated scientist in bioinformatics who is interested in Molecular Systems Immunology, T cell epigenomics and molecular mechanisms of immune mediated diseases. Successful applicant will join our international research groups at Turku Centre for Biotechnology, BioCity Turku, Turku, Finland and will be co-supervised by Dr. Laura Elo, Research Director in Bioinformatics and Dr. Riitta Lahesmaa, Academy professor, at Turku Centre for Biotechnology, University of Turku, Finland.
Description of recruiting organization
Turku Centre for Biotechnology (www.btk.fi) is a joint department of University of Turku (www.utu.fi) and Åbo Akademi University, providing high-end technologies and expertise to academic and industrial researchers and a stimulating multidisciplinary and international research environment. Successful applicant will
The Medical Bioinformatics Centre and the Computational Biomedicine Group of Research Director Laura Elo (http://elolab.utu.fi/ ) develops computational data analysis tools and mathematical models for biomedical research, with the eventual goal of improving the diagnosis, prognosis and treatment of complex diseases, such as diabetes, cardiovascular diseases and cancer. A specific focus is on analysing and interpreting data generated by modern high-throughput biotechnologies, such as deep sequencing and mass-spectrometry proteomics.
Molecular Systems Immunology group (http://www.btk.fi/research/research-groups/lahesmaa/ ) aims at understanding the regulation of human immune system to predict, prevent and treat immune mediated disorders. We study epigenetic and transcriptional regulation of T cells and molecular mechanisms of immune mediated diseases such as Type 1 Diabetes.
Description of the position to fill
The postdoctoral researcher will work on projects aiming at regulation of immune response in health and immune mediated disorders. These include detection of biomarkers for immune mediated diseases as well as unraveling the underlying molecular mechanisms. She/he will join our multidisciplinary team with backgrounds in mathematics, statistics, computer science, bioinformatics, biology and medicine.
The work of the postdoctoral researcher involves development and application of computational and statistical methods for the analysis of high-throughput molecular data, with a focus on next generation sequencing data and their combination with other omics data.
The position is for 2 years. Starting date is 1.11.2018 and is negotiable. The salary is in accordance with the universities salary system (for teaching and research personnel) level 5-6 where the work specific salary component is 2893,95 – 3374,18 €/month. In addition, there is a share increase based on personal performance, which is at most 46.3% of the base salary. There is a trial period of six months.
Qualifications
Successful applicants have:
– A relevant Doctoral degree (e.g. bioinformatics, computational biology, biostatistics)
– Scientific publications in high impact international journals
– Previous experience in next generation sequencing, epigenomic and genomic research and related analysis platforms and tools
– Experience in R, Matlab or other mathematical/statistical software
– High level of motivation, self-initiative and independency
– Excellent team work and communication skills in English (both oral and written)
– Previous experience in immunology is considered an advantage
– International research experience and experience in supervision of students is considered an advantage
Application
The applications for the position should be submitted latest on 30.09.2018 using the electronic system. The application should include a motivation letter, CV, list of publications, contact information for 3 referees, and copies of relevant degree certificates. A link to the electronic application system can be found on top of the position advertisement from the following link: www.utu.fi/careers .
For further information on the positions please contact: Prof. Riitta Lahesmaa, e-mail: riitta.lahesmaa@utu.fi . Enquiries on the application procedure may be directed to HR specialist Paula Luoma, paula.luoma@utu.fi .
This is an interesting and developing position in a rapidly growing area of science – so we encourage you to send your application as soon as possible. We will interview suitable candidates already during the application process. We welcome you cordially to our multicultural working community.
21.9.2018 | Ajankohtaista
Postdoctoral researcher or project researcher to study immunoregulation in Molecular Systems Immunology Group at Turku Centre for Biotechnology
Our international multidisciplinary research group (https://www.btk.fi/research/molecular-systems-immunology/) led by Academy Professor Riitta Lahesmaa is based at Turku Centre for Biotechnology (the Centre), BioCity Turku, Turku, Finland. We are seeking for a motivated postdoctoral researcher or project researcher with possibility to continue work as a doctoral candidate.
Disorders in immune system and lymphocyte function lead to inflammatory diseases e.g. rheumatoid arthritis and Type 1 Diabetes. Project will focus on studying the molecular mechanisms underlying immune mediated diseases aiming at enabling individualized treatment in the future.
Description of recruiting organization
Molecular Systems Immunology group aims at understanding the regulation of human immune system to predict, prevent and treat immune mediated disorders. We study epigenetic and transcriptional regulation of T cells and molecular mechanisms of immune mediated diseases such as Type 1 Diabetes.
Turku Centre for Biotechnology is a joint research institute of University of Turku and Åbo Akademi University. The mission of the Centre is to promote high quality research and training. The Centre has excellent state-of-the-art technology platforms and expertise in NGS, epigenomics, proteomics, computational biology and high-end cell imaging.
Qualifications
Successful candidates have:
- A relevant doctor’s degree (postdoctoral researcher) or a relevant master’s degree (project researcher) e.g. in life sciences or in biomedicine
- High level of motivation, self-initiative and independency
- Excellent team work and communication skills in English (both oral and written)
- First-rate molecular and cell biology knowledge and skills with a strong background in epigenetics.
- Strong publication record in international journals (postdoctoral researcher) at least in one of the following areas: immunology, molecular and cellular biology, autoimmunity, genetics, epigenetics.
Application
The salary is in accordance with the University salary system (for teaching and research personnel) level 5 (postdoctoral researcher) where the work specific salary component is 2 893,95 €/month or levels 3-4 (project researcher), where the work specific salary component is 2203,25 2500,06 €/month. In addition, there is a share increase based on the personal performance, which is, at most, 46.3% of the base salary. The position starts at earliest on Nov 1st, 2018 (or as agreed). The positions are initially for two years, one optional year possible. There is a trial period of six months.
The deadline for applications is Sept 30th, 2018 (23:59). A link to the electronic application system can be found from the following link: www.utu.fi/careers . Please include a CV, full publication list, list of selected publications and contact information for three references in your application.
For further information on the positions please contact: Prof. Riitta Lahesmaa, e-mail: riitta.lahesmaa@utu.fi . Enquiries on the application procedure may be directed to HR specialist Paula Luoma, paula.luoma@utu.fi .
