The University of Eastern Finland is inviting applications for a Postdoctoral Researcher / Project Researcher / Early Stage Researcher (Biomedical Informatics) position in Kuopio. The position will be filled for a two-year term from 1 January 2021 (or as agreed). Please find more information below and submit your application no later than 28 December 2021. (Extended application period)
Role and salary
As our new Postdoctoral, Project or Early Stage Researcher in Biomedical Informatics, you will be working in the research group led by Associate Professor and Academy Research Fellow Vittorio Fortino in the Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, Kuopio Campus.
Our group studies and implements data mining algorithms (including machine learning algorithms) to tackle biomedical questions, such as biomarker and drug discovery. Applicants with profound knowledge of (1) bioinformatics tools to analyse genomics and transcriptomics data; and (2) machine learning algorithms are encouraged to apply.
More details on the research group and research interests can be found at
The position is part of a project aiming to develop machine learning approaches
1) to identify clinically relevant cancer subtypes from multi-omics datasets (TCGA);
2) to learn how to match cancer cell lines with cancer subtypes via omics data (TCGA, CCLE, GDSC, and GTEx); and
3) to discover synergistic (and safer) drug combinations from available pharmacogenomics data (e.g. LINCS 1000).
The position will be filled for a two-year term from 1 January 2021 (or as agreed) due to it pertaining to a specific project. A probationary period is applied to all new members of the staff.
The salary of the position is determined in accordance with the salary system of the Finnish universities. The salary comprises two components: a job requirement component and a personal performance component. For a Postdoctoral Researcher / Project Researcher, the job requirement component is 3,000.49 €/month, based on level 5 of the job requirement chart for teaching and research staff. For an Early-stage Researcher, the job requirement component is 2,078.27 – 2,591.28 €/month, based on levels 2-4 of the job requirement chart for teaching and research staff. The personal performance component can be between 6-50 % of the above-mentioned sums.
At the beginning, the salary will be 3,180.52 – 3,660.60 € /month, as Postdoctoral / Project Researcher or 2,202.97-2,746.76 € /month as Early-Stage Researcher.
Our requirements and expectations
The appointed researcher will have a central role in implementing and applying machine learning methods for the analysis of large-scale omics data. They will have an inquisitive mindset, a proactive attitude, and the desire to further develop their skills for data science and machine learning.
The successful candidate will:
Have a PhD in Bioinformatics, Computational Science or a related discipline for the Postdoctoral/Project Researcher position. If the doctoral degree has been awarded less than five years ago, the post will be one of a Postdoctoral Researcher. If the doctoral degree has been awarded more than five years ago, the post will be one of a Project Researcher. In this context, the 5 years refer to a net period time, which does not include parental leaves, or military service.
Have an MSc in Bioinformatics, Biosciences or a related discipline for the Early Stage Researcher position; have completed a suitable higher university degree or an equivalent education abroad which in the country in question would qualify the person for similar academic studies. The candidate shall also be qualified to pursue postgraduate studies at the University of Eastern Finland by enrolling in one of the doctoral programmes of the Faculty of Health Sciences.
Desired knowledge, skills, and abilities that are essential for this position:
A solid computational (informatics/computer science/coding) background is required..
Solid knowledge of, and practical experience in, bioinformatics is required.
Experience of analysis of at least two different types of omics data (e.g. gene expression data, genomic data – GWAS, DNA methylation data, etc.) is required.
Programming experience in a relevant programming language (e.g., R and Python) is required.
Practical experience of working with machine learning methods is required.
Practical experience of working with network analysis is an advantage.
Applicants must be able to work independently and in a team.
Applicants must have good skills in oral and written English.
Previous research experience and ambitions will also count during the evaluation process.
copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas
recommendation letter(s) (if available)
Questions?
For further information on the position, please contact: Associate Professor Vittorio Fortino, +358 29 445 4197, vittorio.fortino@uef.fi.
For further information on the application procedure, please contact Saima-asiatTT@uef.fi
The Functional RNAomics laboratory at the Faculty of Medicine and Health Technology, Tampere University studies gene regulation via RNA processing. By determining how RNA regulation is orchestrated in different cell types, we aim to crack the cellular RNA code and gain critical insights into how aberrations in the RNA machinery result in genetic disorders and cancer. RNA is emerging as a powerful and easily adaptable therapeutic molecule as exemplified by the rapid development of effective mRNA vaccines but a detailed knowledge of RNA regulation in cells is a prerequisite to realise the full potential of RNA-based therapeutic and diagnostic development. We integrate cell biology approaches with mechanistic studies, global mapping of RNA repertoires, RNA binding protein interactions and proteomics profiles to reveal the functional role of RNA-protein complexes in different cell lineages and in disease.
Job description
We are looking for two post-doctoral researchers on full- or part-time basis:
The postdoctoral researcher in cell and molecular biology will conduct experimental research involving advanced molecular biology techniques including sample preparation for short-read and long-read RNA sequencing, cell and organoid cultures, and various biochemistry methods. The work involves experimental planning, detailed recording of data, data analysis and reporting of results.
The post-doctoral research in bioinformatics will analyse a range of large-scale datasets including short-read RNA sequencing, long-read direct RNA sequencing and proteomics data. The work includes the application of existing data analysis pipelines as well as the development of new computational methods. It also involves experimental planning, detailed recording of data and reporting of results.
Requirements
The positions are mostly intended for recently graduated researchers, so that they may gain further experience and advance their careers. You should have a PhD degree in biochemistry, genetics, molecular biology, bioinformatics/computational biology or a related subject area. We expect a competence to pursue independent scientific work. You should be fluent in spoken and written English and have a solid experience either in (1) cell and molecular biology or (2) computational biology/bioinformatics. Skills in both wet and dry lab research are considered an advantage.
You should be able to communicate with experimental and computational biologists as a member of a multidisciplinary team. We appreciate experience of studying or working abroad and contacts to international research community. We are looking for versatile and independent researchers with experience in the closely related area of the positions. It is expected that you will be able to contribute to the supervision of M.Sc. and Ph.D. students. Please be prepared to provide a proof of your merits when requested.
Tampere University is a unique, multidisciplinary and boldly forward-looking, evolving community. Our values are equity, openness, diversity, responsibility, courage, critical thinking, erudition bildung, and learner-centredness. We hope that you can embrace these values and promote them in your work.
We offer
The position will be filled for a fixed-term period of 2 years in the first instance. The starting date is 1st February 2022 or as mutually agreed. A trial period of six months applies to all our new employees.
The salary will be based on both the job requirements and the employee’s personal performance in accordance with the Finnish University Salary System. The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff).
We offer a wide range of staff benefits, such as occupational health care, flexible working hours, excellent sports facilities on campus and several restaurants and cafés on campus with staff discounts. Please read more about working at Tampere University.
We offer a world-class research environment in an internationally recognized research group. We have strong collaborative networks and offer great opportunities for researchers to develop their careers in an international setting.
How to apply
Please submit your application through our online recruitment system. The closing date for applications is 10th December 2021 (at 23.59 EET /UTC+2). Please write your application and all accompanying documents in English and attach them in PDF format.
The closing date for applications has been extended until 20 December, 2021.
Applications should include the following documents:
Description of your research focus, qualifications, previous research fields and main research achievements (1-2 pages)
For more information, please contact:
Professor, Group Leader Minni Änkö, minna-liisa.anko (at) tuni.fi
***
Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fi
Functional RNAomics -tutkimusryhmä Tampereen yliopiston Lääketieteen ja terveysteknologian tiedekunnassa tutkii RNA-välitteistä geenien säätelyä. Tutkimuksemme tavoitteena on selvittää, miten RNA-tason säätely toimii eri solutyypeissä. Tarkoituksenamme on ‘murtaa solujen RNA-koodi’ ja siten ymmärtää, mikä RNA-säätelyn rooli on geneetisien sairauksien ja syövän synnyssä. RNA on osoittautunut monimuotoiseksi molekyyliksi, jota voidaan soveltaa erilaisten sairauksien hoidossa tai ehkäisyssä, esimerkkinä hiljattain kehitetyt RNA-rokotteet. Jotta RNA:ta voidaan turvallisesti hyödyntää diagnostiikassa ja hoitomuotona, meidän täytyy kuitenkin ensin selvittää, kuinka RNA-säätely toimii solutasolla. Yhdistämme tutkimuksessamme erilaisia solu- ja molekyylibiologian menetelmiä sekä RNA- ja proteomitason profilointia.
Tehtävänkuvaus
Tutkijatohtori/solu- ja molekyylibiologia: molekyyli- ja solubiologian tutkimuksen suunnitteleminen, laboratoriatehtävät mukaan lukien soluviljely, sekvenointikirjastojen valmistaminen erilaisiin RNA-sekvenointisovelluksiin sekä erilaiset biokemian menetelmät, tulosten analysointi ja raportointi.
Tutkijatohtori/bioinformatiikka: RNA-sekvenointi- ja proteomidatan analysointi käyttäen olemassaolevia menetelmiä, uusien analyysimenetelmien kehittäminen, tulosten reportointi.
Tutkimusryhmän työkieli on englanti, joten sujuva englanninkielen taito on välttämätön. Tutkijatohtorin tehtäviin kuuluu nuorempien tutkijoiden ja opiskelijoiden ohjaus.
Hakuohjeet
Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta.
Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).
The Functional RNAomics laboratory at the Faculty of Medicine and Health Technology, Tampere University studies gene regulation via RNA processing. By determining how RNA regulation is orchestrated in different cell types, we aim to crack the cellular RNA code and gain critical insights into how aberrations in the RNA machinery result in genetic disorders and cancer. RNA is emerging as a powerful and easily adaptable therapeutic molecule as exemplified by the rapid development of effective mRNA vaccines but a detailed knowledge of RNA regulation in cells is a prerequisite to realise the full potential of RNA-based therapeutic and diagnostic development. We integrate cell biology approaches with mechanistic studies, global mapping of RNA repertoires, RNA binding protein interactions and proteomics profiles to reveal the functional role of RNA-protein complexes in different cell lineages and in disease.
Job description
We are looking for two post-doctoral researchers on full- or part-time basis:
The postdoctoral researcher in cell and molecular biology will conduct experimental research involving advanced molecular biology techniques including sample preparation for short-read and long-read RNA sequencing, cell and organoid cultures, and various biochemistry methods. The work involves experimental planning, detailed recording of data, data analysis and reporting of results.
The post-doctoral research in bioinformatics will analyse a range of large-scale datasets including short-read RNA sequencing, long-read direct RNA sequencing and proteomics data. The work includes the application of existing data analysis pipelines as well as the development of new computational methods. It also involves experimental planning, detailed recording of data and reporting of results.
Requirements
The positions are mostly intended for recently graduated researchers, so that they may gain further experience and advance their careers. You should have a PhD degree in biochemistry, genetics, molecular biology, bioinformatics/computational biology or a related subject area. We expect a competence to pursue independent scientific work. You should be fluent in spoken and written English and have a solid experience either in (1) cell and molecular biology or (2) computational biology/bioinformatics. Skills in both wet and dry lab research are considered an advantage.
You should be able to communicate with experimental and computational biologists as a member of a multidisciplinary team. We appreciate experience of studying or working abroad and contacts to international research community. We are looking for versatile and independent researchers with experience in the closely related area of the positions. It is expected that you will be able to contribute to the supervision of M.Sc. and Ph.D. students. Please be prepared to provide a proof of your merits when requested.
Tampere University is a unique, multidisciplinary and boldly forward-looking, evolving community. Our values are equity, openness, diversity, responsibility, courage, critical thinking, erudition bildung, and learner-centredness. We hope that you can embrace these values and promote them in your work.
We offer
The position will be filled for a fixed-term period of 2 years in the first instance. The starting date is 1st February 2022 or as mutually agreed. A trial period of six months applies to all our new employees.
The salary will be based on both the job requirements and the employee’s personal performance in accordance with the Finnish University Salary System. The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff).
We offer a wide range of staff benefits, such as occupational health care, flexible working hours, excellent sports facilities on campus and several restaurants and cafés on campus with staff discounts. Please read more about working at Tampere University.
We offer a world-class research environment in an internationally recognized research group. We have strong collaborative networks and offer great opportunities for researchers to develop their careers in an international setting.
How to apply
Please submit your application through our online recruitment system. The closing date for applications is 10th December 2021 (at 23.59 EET /UTC+2). Please write your application and all accompanying documents in English and attach them in PDF format.
Applications should include the following documents:
Description of your research focus, qualifications, previous research fields and main research achievements (1-2 pages)
For more information, please contact:
Professor, Group Leader Minni Änkö, minna-liisa.anko (at) tuni.fi
***
Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fi
Functional RNAomics -tutkimusryhmä Tampereen yliopiston Lääketieteen ja terveysteknologian tiedekunnassa tutkii RNA-välitteistä geenien säätelyä. Tutkimuksemme tavoitteena on selvittää, miten RNA-tason säätely toimii eri solutyypeissä. Tarkoituksenamme on ‘murtaa solujen RNA-koodi’ ja siten ymmärtää, mikä RNA-säätelyn rooli on geneetisien sairauksien ja syövän synnyssä. RNA on osoittautunut monimuotoiseksi molekyyliksi, jota voidaan soveltaa erilaisten sairauksien hoidossa tai ehkäisyssä, esimerkkinä hiljattain kehitetyt RNA-rokotteet. Jotta RNA:ta voidaan turvallisesti hyödyntää diagnostiikassa ja hoitomuotona, meidän täytyy kuitenkin ensin selvittää, kuinka RNA-säätely toimii solutasolla. Yhdistämme tutkimuksessamme erilaisia solu- ja molekyylibiologian menetelmiä sekä RNA- ja proteomitason profilointia.
Tehtävänkuvaus
Tutkijatohtori/solu- ja molekyylibiologia: molekyyli- ja solubiologian tutkimuksen suunnitteleminen, laboratoriatehtävät mukaan lukien soluviljely, sekvenointikirjastojen valmistaminen erilaisiin RNA-sekvenointisovelluksiin sekä erilaiset biokemian menetelmät, tulosten analysointi ja raportointi.
Tutkijatohtori/bioinformatiikka: RNA-sekvenointi- ja proteomidatan analysointi käyttäen olemassaolevia menetelmiä, uusien analyysimenetelmien kehittäminen, tulosten reportointi.
Tutkimusryhmän työkieli on englanti, joten sujuva englanninkielen taito on välttämätön. Tutkijatohtorin tehtäviin kuuluu nuorempien tutkijoiden ja opiskelijoiden ohjaus.
Hakuohjeet
Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta.
Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).
The Melanoma Immune Oncology Research Group (MIORG) as part of the Institute of Biomedicine, University of Turku is seeking an enthusiastic and competent Postdoctoral Researcher to collaborate in a project related to melanoma immunobiology and immunotherapy, led by Dr Rogerio de Figueiredo. The project employs cutting-edge technologies and state-of-the-art approaches to immune profile metastatic melanoma bioresources from animal models and patient samples.
Key Responsibilities
Conduct scientific research related to metastatic melanoma immunotherapy, including cancer immunobiology, drug discovery using in vitro and in vivo assays biochemical and pharmacological assays, and data analysis.
Essential Qualifications
PhD degree in a relevant discipline (e.g. cell biology, molecular biology, biomedicine, biochemistry and immunology)
Desirable Qualifications
Animal and human work experience. License for animal work is desirable.
Competence in tissue culture methods and experience in processing human/animal samples.
Sufficient skills with RNA isolation, quantitative RT-PCR, protein isolation and western blot and ELISA assays.
Good experience with tissue immunofluorescence and immunohistochemistry techniques.
Experience in single cell staining for Flow Cytometry and CyTOF.
Organization skills for inventory of consumables and protocols
Experience with statistics and bioinformatics.
The successful candidate should show initiative and independence on the bench, possess good communication skills and the ability to work effectively as part of a team.
Salary
The salary is based on the Finnish collective agreement. The position belongs to the category of teaching and research personnel. Thus the total salary is estimated to be in the range of 3180-3500 €/month. The salary will be defined based on the applicant’s competence and work experience.
Duration of the Contract
The successful applicant is expected to start as soon as possible, but the starting date is negotiable.
The position is fixed-term for max. 2 years according to the funding granted to the project. There is a possibility for extension.
The position is subject to a six-month trial period.
What to do next
Applications must be submitted by 19 November 2021 at the latest (23.59.59Finnish time) via the University of Turku electronic application form. Apply for the job at www.utu.fi/careers (“Fill the form”).
In your application, please include
a motivation letter
CV
copies of degree certificates
at least one recommendation letter
The top candidates will be interviewed.
For further information about the position, please contact the Group Leader, Adjunct Professor, Academy Research Fellow Rogerio de Figueiredo (rogerio.defigueiredo@utu.fi).
In case you need help with the application process, please turn to HR Specialist Kristiina Nuutila (kristiina.nuutila@utu.fi), Tel. +358 503135224.
The laboratory of Dr. Tommi Kajander at the Institute of Biotechnology, HiLIFE, University of Helsinki, Finland, is inviting applications for post-doctoral researcher in the area of protein biochemistry and structural biology in a joint project with Prof. Mart Saarma’s laboratory. We are seeking for dedicated and enthusiastic scientist to work on the structure and function of novel endoplasmic reticulum effector protein-receptor interactions in ER stress response regulation. Main targets are CDNF and MANF proteins and their interaction complexes in the ER.
The Institute of Biotechnology is a research institute at University of Helsinki, located in the Viikki science park. The institute harbors ~35 research groups and 250 researchers, and it operates at the highest international level. For more information on the Institute, please visit https://www.helsinki.fi/en/hilife-institute-of-biotechnology. The institute has excellent infrastructure for structural biology (X-ray, CryoEM, NMR) including the crystallography core facility run by the PI.
The post-doctoral applicants should hold PhD in biochemistry or a related field. Strong experience in protein biochemistry including cloning and mutagenesis and protein expression and purification, from various hosts and good communication skills in English are required. Knowledge and experience in structural biology and molecular biophysics techiques and cell culture is beneficial. This is an opportunity to work on high impact targets and obtain in depth technical skills in the research area. The position will provide excellent opportunities for collaborations, as this is a joint project in close collaboration with Prof. Mart Saarma’s group, with also potential international and national collaborations and visits to e.g. synchrotron sources in Europe (ESRF, DLS, MAXIV). An attitude to carry out ambitious research projects, good problem solving skills, goal-oriented mind-set and willingness to learn and apply new methodologies is highly appreciated. The working language of the laboratory is English; knowledge of Finnish is not a requirement.
The postdoctoral position is initially limited to 1 year, with a possibility of extension to three years. The salaries will be based on the University salary scheme (level 5) for teaching and research personnel composed of both task specific and personal performance component The position is available immediately or as agreed.
Application should include the following documents as a single pdf file (max 5 pages): CV (max 2 pages), list of publications, motivation letter (max 1 page) including a description of your research interests, and the names and contact details of at least two referees. Please submit your application, together with the required pdf attachment, through the University of Helsinki electronic recruitment system by clicking on the ‘Apply for job’ button. Internal applicants (i.e., current employees of the University of Helsinki) should submit their applications through the SAP HR portal. For technical support regarding the recruitment system, please contact ‘rekrytointi@helsinki.fi’.
The deadline for the applications is 31st of August, 2021, or until suitable candidate have been found.
For technical support regarding the recruitment system, please contact rekrytointi@helsinki.fi.
Selected recent references related to project and the laboratory: Kovaleva V, Yu LY, Ivanova L, Nam J, Eesmaa A, Kumpula EP, Huiskonen J, Lindholm P, Voutilainen M, Karelson M, Saarma M. MANF regulates unfolded protein response and neuronal survival through its ER-located receptor IRE1α bioRxiv 2020.09.22.307744
Eesmaa A, Yu LY, Göös H, Nõges K, Kovaleva V, Hellman M, Zimmermann R, Jung M, Permi P, Varjosalo M, Lindholm P, Saarma M. The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor. J Biol Chem. 2021 Jan 15;296:100295.
Lindahl M, Saarma M, Lindholm P. Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential. Neurobiol Dis. 2017 Jan;97(Pt B):90-102.
We are now looking for a highly motivated Postdoctoral Researcher to join the research group of Rajaram Venkatesan in an Academy of Finland funded project aiming to understand the structure and function of a lipid transporting protein complex in mycobacteria.
Description
Applications are invited for a full-time fixed-term postdoctoral researcher position in the research group of Rajaram Venkatesan in the Protein and Structural Biology Research Unit, at the Faculty of Biochemistry and Molecular Medicine. The Venkatesan research group works on the structural and functional aspects of enzymes and protein complexes involved in lipid metabolism and transport in human and pathogenic organisms. The Faculty provides an excellent environment for doing cutting edge research in protein science and structural biology with access to state-of-the-art facilities located at Oulu, Finland, as well as across Europe. The research project concerns the study of mammalian-cell-entry (Mce) complexes from mycobacteria to understand the assembly, structure and function. The main tasks of the research project include but is not limited to the isolation and characterization of these Mce complexes from mycobacteria using a variety of biophysical and structural methods. The position is for an Academy of Finland funded project and a fixed-term position for a period of two years. Besides research, the position also includes some teaching duties in the degree programs of the Faculty.
Qualification requirements
The successful candidate for the postdoctoral researcher position must possess a Doctoral degree in the field of protein science, structural biology, biochemistry, microbiology or related fields. This position is primarily addressed to doctorates whose dissertation is not older than two years. The candidate should have a strong interest in structural, molecular and microbiology research.
Previous demonstrated experience in handling membrane proteins, protein-protein interaction studies, (cryo) electron microscopy and microbiology techniques is considered a significant advantage. The selected candidate should be able to work independently as well as in a group with a drive to excel in research. Fluency in both written and spoken English is required. Most importantly, we expect the candidate to have a high motivation to conduct high-level biochemistry research.
What we offer
We offer a research environment with excellent technological facilities and a motivating and supporting international community at the Faculty of Biochemistry and Molecular Medicine, University of Oulu. We can also offer access to state-of-the-art facilities located at Oulu, Finland as well as across Europe for doing cutting edge research in protein science and structural biology. We offer you a place in a highly talented research group, working to solve globally significant research problems. University´s wide variety of support services are at your disposal, allowing you to focus on research work. The position is fixed-term for 2 years as of 01.09.2021 or as soon as possible thereafter. A trial period of 6 months is applied in the position.
Salary
The salary will be based on the demand level 5 of the salary system of Finnish Universities for teaching and research personnel. In addition, a salary component based on personal work performance will be paid (maximum of 50% of the job-specific component). Starting gross salary will be approx. 3500 € per month.
How to apply
Applications, together with all relevant enclosures, should be submitted using the electronic application form by August 2, 2021 (23:59 Finnish local time). The application should be written in English and include the following:
1) A motivation letter(max. 2 pages) summarizing applicant’s professional experience and expertise and describing why applicant is interested in this position. Also, information on personal research interests, experience and career plans are valuable to provide here.
2) A complete Curriculum vitae (max. 4 pages) preferably in accordance with the guidelines of the Finnish Advisory Board on Research Integrity http://www.tenk.fi/en/template-researchers-curriculum-vitaeincluding a list of publications and contact information of at least two referees who may be asked to give a statement on the candidate.
Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Top candidates will be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.
Further information
For further information, informal enquires can be sent to Rajaram Venkatesan by E-mail (rajaram.venkatesan@oulu.fi) with a subject line “Regarding postdoctoral position”.
Postdoctoral researcher with extensive experience in animal work, particularly mice or hamsters. Two projects available: 1) Stabilization of vaccines so that can be stored at room temperature. 2) Understanding how SARS-CoV-2 enters and spreads in the upper respiratory epithelium.
The position is available from Sptember 1st 2021 and it is for at least 1.5 years. For more information please contact giuseppe.balistreri@helsinki.fi
The HiLIFE – Institute of Biotechnology (BI), located in the Viikki science park, is a research institute at University of Helsinki. The institute harbors ~35 research groups and 250 researchers, and it operates at the highest international level. For more information on the Institute, please visit https://www.helsinki.fi/en/hilife-institute-of-biotechnology.
The laboratory of Dr. Jette Lengefeld is inviting applications for post-doctoral researchers and/or PhD-students in cell biology and stem cell biology.
The failure to regenerate tissue with age is a major health issue. A contributor to this decline is the loss of stem cell function. Despite the essential role of stem cells, it is still unclear how they fail to maintain their functions during ageing and disease. We discovered a new aspect of stem cell ageing in vivo: cellular enlargement. With age and damage, stem cells increase in size causing their functional decline. However, we are only beginning to understand how size impacts stem cell fitness and the physiological importance of this process remains unsolved.
The Lengefeld research group uses blood (hematopoietic) stem cells from mice and human bone marrow donations to address these fascinating questions:
What pathways cause stem cell dysfunction during their enlargement? We use blood (hematopoietic) stem cells of mouse models to identify the molecular mechanisms impairing fitness of large stem cells from a metabolic perspective.
Can we rejuvenate stem cells after aging and damage? We explore approaches to rejuvenate stem cells and investigate the effects on cellular ageing and organismal health.
Does deregulation of size lead to cancer? We utilize blood stem cells from mice and humans to identify factors that facilitate leukaemia in vivo and to investigate the underlying mechanisms.
The post-doctoral applicants should hold PhD in cell biology, stem cell biology, cell size regulation or a related field. Strong expertise in stem cell biology and experience working with mice is highly beneficial. The PhD-student applicants should obtain MSc or related degree in the biology field latest by August 2022, and have a strong interest to carry out cutting-edge research. The positions will provide multiple opportunities for collaborations with potential lab visits abroad. An attitude to drive own research and work in an intra and inter team fashion is highly appreciated. In return, the candidates are offered an access to a wide variety of methodologies and advanced techniques. The working language of the laboratory, the BI and HiLIFE is English and good communication skills in English are required.
The postdoctoral researcher and PhD-student positions are initially limited to 2 and 4 years, respectively, with a possibility of extension. A trial period of 6 months will be applied, and the salaries will be based on the University salary scheme for teaching and research personnel composed of both task specific and personal performance components.
Application should include the following documents as a single pdf file: CV, list of publications, motivation letter including a description of your research interests, and the names and telephone numbers of at least two referees.
Please submit your application, together with the required attachments, through the University of Helsinki electronic recruitment system by clicking the “Apply for the position” – link below. Applicants employed by the University of Helsinki must submit their application through the SAP HR portal.
The deadline for the applications is 8th of July 2021, but the positions will be filled immediately once suitable candidates have been identified.
We are now looking for a PostdoctoralResearcher to join our multidisciplinary FET OPEN EU consortium project “MindGAP”
Research description
The MindGAP project centers around the hypothesis that brain-derived extracellular vesicles (EVs) present in blood can have a positive effect on disease outcomes (https://mindgap-fet-open.eu/home).
MindGAP WP3 is aiming to identify and characterize CNS EV markers targeting them to blood and to identify biomarkers of successful mindfulness in cancer survivors for the development of microfluidic testing device.
The MindGAP project work involves such tasks as EV isolation from biofluids and primary human neural cell cultures, characterization of EV surface proteome, RNA cargo analysis, mindfulness biomarker identification and validation. These studies are performed in collaboration with the rest of the FET OPEN consortia in Sweden, Portugal, and Finland (VTT).
Open position
We are looking for a candidate with expertise in biochemistry, biomarker identification and validation, strong molecular biology background, and experience with liquid biopsy/biofluids or EV research.
The selected applicant will perform hands-on experiments in the laboratory, participate in relevant seminars and lectures, write research documentation and reports, and perform teaching duties at the Oulu University Faculty of Biochemistry and Molecular Medicine.
The position is a fixed term contract for one year. The selected applicant is expected to apply for personal funding to advance their research career.
Required qualifications
The applicant must have a PhD degree in life sciences, at the commencement of the position, that was awarded a maximum of four years ago.
Applicants should have a degree in molecular biology, biochemistry, or a related field.
Doctoral students whose PhD thesis will be submitted by the application deadline are eligible to apply.
An ability to pursue independent research, work productively in a team, and supervise younger scientists are necessary.
The candidate should have good written and verbal English skills.
The successful candidate is expected to have strong expertise in membrane protein isolation and analysis (mass spec sample preparation and analysis), protein chemistry, molecular biology. Experience in medium-throughput protein and nucleic acid biomarker assays, along with liquid biopsy, EV analysis, bioinformatics, and preparation of primary neural cell cultures from human biopsies will be advantageous.
What we offer
We offer you a place in a highly talented research group, working to solve globally significant research problems.
In addition to modern research facilities, we offer you personnel benefits such as free occupational healthcare, affordable sport services and endless opportunities to develop your skills and competences.
Regular salary is paid 12 months per year, including paid leave and an additional holiday bonus in the summer.
The successful candidate will receive also benefits provided by the Finnish government to residents, for example possibility to obtain access to the national healthcare system, tax benefits for employees with children and high-quality, affordable childcare services.
Salary
A salary in accordance with the Finnish universities salary system (for teaching and research personnel): level 5. In addition, a salary component based on personal work performance will be paid (maximum of 50% of the job-specific component). Starting gross salary will be approx. €3100 € per month.
How to apply
Applications, together with all relevant enclosures, should be submitted using the electronic application form by 04.06.2021. The application should be written in English and include the following:
1) A motivation letter describing prior knowledge on the subject matter and personal research interests with career plans (max. 2 pages) 2) Complete CV containing contact information of at least two references 3) List of publications 4) Certificates/Diplomas: Scanned copies of relevant degree certificates must be included. If the original documents are not in English, Finnish or Swedish, each document must be accompanied by an official certified translation into English or Finnish
Only applications submitted through the online recruitment system with the required attachments will be considered. Top candidates will be invited to an online interview.
Further information
The position is fixed term for maximum of one year as of August 1, 2021 or as soon as possible thereafter. A trial period of 6 months is applied to the position.
For additional information, please contact
Project leader Dr. Genevieve Bart, Adj. Professor, e-mail: genevieve.bart(at)oulu.fi Principal Investigator Dr. Seppo Vainio, Professor, e-mail: seppo.vainio(at)oulu.fi
The North changes the world – more sustainable, more intelligent, more humane. We, at the University of Oulu, work as part of the international science community to produce new scientific information and science-based solutions. Creating new, taking responsibility, and succeeding together are values that build a strong foundation for all our actions. We offer a working environment for approximately 3 000 employees, where individuals can cultivate their skills, do meaningful work, and develop professionally. Our university’s several specialized research and service units enable extensive and diverse development and career opportunities for experts in various fields.
Biocenter Oulu (BCO) is strategic focus institute at the University of Oulu and offers a high-level international and multidisciplinary environment supplied with cutting-edge open access research infrastructure services.
The Eklund laboratory invites applications for a Postdoctoral Researcher position. The project aims to study vascular pathologies and to establish novel therapeutic approaches. The project is part of the Academy of Finland’s Flagship Programme GeneCellNano focusing on the innovation and commercial development of new biological drugs (advanced therapy medicinal products, ATMPs), biomarkers and diagnostic tools. The Flagship Programme provides the long-term support for high-quality research at various career stages, increases the societal impact emerging from the research in close connections to the business sector. In the GeneCellNano Flagship, the successful applicant will be part of an consortia of four Finnish Universities and Finnish Red Cross Blood Service jointly working to develop new treatments for chronic diseases. For more information please visit:
We are looking for a highly motivated and enthusiastic postdoctoral researcher. We offer a full-time position preferentially starting in August 2021 and lasting until the end of 2024. Work will be carried out in the research group headed by Professor Lauri Eklund (Faculty of Biochemistry and Molecular Medicine and Biocenter Oulu, University of Oulu) focusing on endothelial cell and vascular biology in basic and translational research. In the Flagship, Eklund team contributes to the identification of signaling pathways and target molecules for the development of new treatment strategies for vascular and neurodegenerative disease affecting vision. Aim is to dissect disease processes and to test therapeutic potential of novel ATMPs in genetic mouse models using gene therapy approaches, endothelial cell/biochemical studies, and advanced microcopy.
Qualifications and Requirements
To successfully occupy the position, the candidate must possess a PhD degree and have expertise in the field of molecular, cell or developmental biology. Degree must have been completed before starting the position and/or must not be obtained more than 10 years ago. Ability to pursue independent research, work productively in a team, supervise younger scientists, good scientific presentation skills, excellent writing and fluency in English are required. Prior experience and knowledge of analysis of gene-modified mice, histological and imaging methods, preclinical disease modeling, endothelial cell and vascular biology are considered as an advantage. When assessing the applicant’s qualifications, additional issues to be considered will include scientific publications, supervision experience, success in acquiring funding, activity in the scientific community and familiarity with the research field.
What we offer
You will become a part of a highly talented, multidisciplinary research team working on strategically and globally significant research area.
In addition to your team, outstanding infrastructural resources and specialized core facility service laboratories provided by Biocenter Oulu and the Faculty of Biochemistry and Molecular Medicine will support your work so that you can excel in your research.
There is a wide variety of HR support services and personnel benefits provided by University of Oulu. These include free time corresponding to holidays and free occupational health care services. The successful candidate will receive also benefits provided by the Finnish government to residents and their families, for example possibility to obtain access to the national healthcare system, tax benefits for employees with children and high-quality affordable childcare and school services. For the fourth year in a row, Finland has been evaluated as the world’s happiest country according to the UN-sponsored World Happiness Report survey data.
A salary is in accordance with the Finnish universities salary system (for teaching and research personnel) level 5. In addition, a salary component based on personal work performance will be paid (maximum of 50% of the job-specific component). In practice, the salary is roughly 3550 € per month (before taxes) for an early stage post doc, depending on the appointee’s qualifications and prior experience. A trial period of six months is applied in the position.
Application
Applications must be submitted using the electronic application form by April 30, 2021 (23:59 Finnish local time), with the following attachments as three separate pdf files:
1) Complete CV containing list of publications and contact information of at least two referees (max. size limit of the attachment is 5 Mbytes).
2) Motivation letter (maximum 1 page) describing prior relevant knowledge in the research field, research interests and career plan (1-2 pages; max. size limit of the attachment is 2 Mbytes).
3) Certificates/Diplomas. Scanned electronic copies of diplomas and transcripts of the records of relevant previous degrees. If the original documents are not in English, Finnish or Swedish, each document must be accompanied by an official certified translation into English or Finnish. (Max. size limit of the attachment is 2 Mbytes).
Applications sent by email will not be considered.
Other relevant information
The eligible applicants fitting best in the research profile expected for the position may be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.