4.12.2017 | Ajankohtaista
Job Description
Job-Title: Assistant/Associate/Professor of Pharmacology, School of Pharmacy, Department of Pharmaceutical Science and Research
Position-Parameters: Tenure-track, 12-month position.
Duties: The successful candidate will be engaged in professional scholarship and research and have up to-date knowledge regarding their own area of expertise. They are expected to develop an active research program that attracts sustained extramural funding in their area of expertise. Their area of interest should involve neuropharmacology and addiction. It is expected that the new faculty member will contribute to and help develop new effective active learning modalities associated with the therapeutics sequence in the professional program, especially in the area of the neurological sciences. The therapeutic sequence integrates the practice of pharmacy in specific disease areas with the underlying pharmacology, medicinal chemistry, and drug mechanism of action at a molecular, cellular, and whole organism level. Integration of the basic sciences with pharmacy practice is expected in areas of research, education, and service.
Required Qualifications
An earned doctorate or other terminal degree in Pharmacology with at least three years of postdoctoral experience is required for appointment at the rank of Assistant Professor. Evidence of national and international recognition; a record of sustainable extramural funding and evidence of excellence in education are required for appointment at the rank of Associate or Full Professor. A pharmacy undergraduate degree and/or experience in pharmacy education/teaching will be preferable; the successful candidate will be a dynamic individual with demonstrated records of excellence in teaching and scholarship, and a commitment to excellence in pharmacy education and research.
Must be able to perform all essential job duties as outlined in the job description.
24.11.2017 | Ajankohtaista
Job title Post-doctoral Research Fellow in Neurobiology
Application closing date: 02/01/2018
Salary: £33518 to £38833 pa – Grade 7
Contract Type: Full-time, Fixed-term
Job category/type: Academic/Research
We wish to appoint a Post-doctoral Research Fellow to support a highly motivated scientist, Professor Edgar Kramer, at the Peninsula School of Medicine of University of Plymouth, UK.
The primary function of the role is to perform collaborative and independent research to study the electrophysiological properties of midbrain dopaminergic neurons and/or the molecular signalling pathways in the dopaminergic circuit in different mouse models. A variety of electrophysiological, genetic, molecular biology and biochemical techniques will be employed, including extra- and intracellular recordings and fast scan cyclic voltammetry on transgenic mice. The work is expected to significantly enhance our understanding of midbrain dopaminergic system function and should shed some light on the etiology and possible therapy of Parkinson disease and drug addiction.
You will be responsible for the provision of specialist research knowledge and expertise that supports neurophysiological work in mice on the dopaminergic system altered in Parkinson disease patients and drug addicts.
You must already have or you should be able to complete in the next few months a PhD in Neuroscience, Neurobiology, Medicine, and Pharmacology or in another related area. Experience in electrophysiological experiments and/or molecular biological approaches in the mouse dopaminergic system and in mouse handling is required. Expertise in stablishing and maintaining an electrophysiological setup and/or in as many techniques as listed above is desirable, and candidates with a strong background in neuroscience and neurodegenerative diseases are particularly encouraged to apply. This position also requires that you have good work ethics, analytical and organisational skills, and an ability to multitask and collaborate well with lab members. Our laboratory is part of the new Derriford Research Facility close to Derriford Hospital on the North Campus which brings together all biomedical research groups and has opened in September, 2017. It is close to Plymouth city centre with its attractive cultural scene and coastline with easy access to the dramatic countryside and some of Britain’s most beautiful beaches in Devon and Cornwall.
This post is a full-time position working 37 hours per week, on a fixed-term basis starting in Spring 2018. Funding is available for 36 months, and renewal upon the first and second year is contingent on mutual agreement and satisfactory performance.
To apply, please complete the online application form attaching a motivation letter, your CV, 3 academic references and a list of publications.
For an informal discussion please contact Dr. Edgar Kramer, Professor of Neurodegenerative Diseases, via e-mail edgar.kramer@plymouth.ac.uk
University of Plymouth is committed to an inclusive culture and respecting diversity, and welcomes applications from all sections of the community and is a Stonewall diversity champion.
The University holds a Bronze Athena SWAN Award which recognises commitment to advancing women’s career in STEMM academia.
University of Plymouth has been recognised by Bloomberg as one of the 50 best UK employers for 2016.
23.11.2017 | Ajankohtaista
A postdoctoral position in zebrafish neuroscience
A new postdoctoral position is available within a research group (Panula group) which works on basic mechanisms in neurologic and psychiatric diseases. This particular project involves phenotyping and production of new zebrafish mutants generated with the CRISPR/Cas9 method.
The group manages a very well equipped zebrafish facility, including microinjection systems, confocal and 2-photon imaging systems, systems for quantitative behavioural analysis, good facilities for molecular cloning and quantitative expression analysis (e.g. quantitative PCR, MCID4 imaging system), and well-established international collaborations. The laboratories are located in the Department of Anatomy and Neuroscience Center (HiLIFE unit) on the Meilahti medical campus of the University of Helsinki. The campus houses about 450 PIs within the areas of life sciences.
Salary will be negotiated according to qualifications and the university salary system. An initial appointment will be made for one year, with possible extension. An ideal candidate has a recent PhD in relevant area (e.g. biosciences, physics), and thorough training and experience in imaging or genome modification methods and management of large datasets, preferably within zebrafish field. Experience in programming, molecular biology, behavioural analysis, and gene expression analysis (transgenic animals, PCR, ish, immunocytochemistry, protein chemistry), high motivation and good communication skills are needed in the multidisciplinary group. Responsibilities include research on zebrafish disease models, imaging, molecular biology, zebrafish breeding and maintenance and participation in guidance of junior group members.
Send a CV, list of publications, and an application with names and contact information of 3 references to Professor Pertti Panula, Neuroscience Center, Department of Anatomy, POB 63 (Haartmaninkatu 8), 00014 University of Helsinki, by December 1, 2017 for immediate attention. Late applications may be considered for this or related positions, but attention is not guaranteed.
23.11.2017 | Ajankohtaista
The University of Oslo is Norway’s oldest and highest rated institution of research and education with 28 000 students and 7000 employees. Its broad range of academic disciplines and internationally esteemed research communities make UiO an important contributor to society.
Department of Biosciences (IBV) is a research and education department at the University of Oslo. The Department has one Centre of Excellence and four research sections. The Department has 52 faculty members and associate professors, and approximately 190 PhD students, post docs and researchers, in addition to technical and administrative staff. The working environment is international, and scientists from over 30 countries contribute to the working environment. The Department aims to maintain high international standards both within research and teaching.
IBV offers research-based education within several aspects of bioscience, including ecology, behavioural ecology, evolution, physiology, microbiology, biochemistry, biomedicine, genetics, bioinformatics and biotechnology. Around 380 students are enrolled in bachelor’s programs, and 90 in master’s programs.
PhD Research Fellowship in Proteomics – Analytical Sciences
Position as PhD Research fellow available at Department of Biosciences, Section for Biochemistry and Molecular Biology, Proteomics group.
The fellowship will be for a period of 3 years. Starting date no later than 01.04.2018.
16.11.2017 | Ajankohtaista
Eligo Bioscience is a VC-backed biotech startup, cofounded by professors and scientists from MIT and Rockefeller (Lu and Marraffini labs). We are developing next-gen therapeutics for precision microbiome engineering and bacteria-associated diseases. Our technology is based on the delivery of genetic circuits (notably CRISPR-Cas) to the microbiome via engineered phage particles.
We are a quickly-growing team of passionate scientists driven by the challenge of solving unmet medical needs. We are recruiting a new cohort of talented scientists to join us to work on one of the most exciting synthetic biology-based drug-development platforms!
15.11.2017 | Ajankohtaista
www.academictransfer.com/43498
Job description
The Translational Research Network for Prostate Cancer (TransPot) is a pan-European Marie Skłodowska-Curie International Training Network (ITN) with a focus on Translational Cancer Research, Cancer Cell Biology and Applied Systems Biology/Systems Medicine. The TransPot research training network will integrate leading academic/private/clinical research scientists and laboratories in Europe with an interest in these research fields to train 11 early stage researchers (ESRs). The consortium will incorporate the latest multi-disciplinary research technologies to understand lethal prostate cancer (PC). TransPot offers a unique and innovative research training programme comprising both basic research (e.g. target validation and drug discovery; biomarker discovery and validation) and transferable skill sets (e.g. cross species onconomics analysis; novel preclinical (culture/in vivo) models).
At Erasmus MC Rotterdam, we will focus on compound screening using dedicated and novel 3D cultured PC therapy-resistant patient-derived xenograft (PDX) models. The results will be validated in tissue slices of PDXs and in clinical PC organoids. As indicated above, the project is highly multidisciplinary and incorporates both target validation and drug testing using various technologies. Intensive collaboration and short-stay visits to our partners in TransPot will complement the research.
Requirements
You are a highly motivated international candidate with a university MSc degree. You have received excellent scientific training in the field of Biomedical Sciences, Medicine or a related field. You have an interest in the molecular biology of (prostate) cancer, underlying signaling pathways, and application of drug screens. Experience with cell culture techniques will be considered a strength. You have outstanding theoretical and experimental research skills, and have a strong team spirit. A strong command of (scientific) English in speech and writing is essential.
You are a national of a member state of the European Union, an Associated Country or any other third country. At the time of selection, you must be in the first four years (full-time equivalent) of your research career and have not been awarded a doctoral degree. You also must not have resided or carried out main activities (work, studies, etc.) in the Netherlands for more than 12 months in the past 4 years.
Being able to present a certificate of good conduct is a condition for the appointment.
Conditions of employment
You will receive a temporary position for 4 years. The gross monthly salary is € 2.279,- in the 1st year and increases to € 2.919,- in the 4th year (scale OIO). The terms of employment are according to the Collective Bargaining Agreement for Dutch University Medical Centers (CAO UMC).
Employer
Erasmus MC
A healthy population and excellence in healthcare through research and education. This is what Erasmus MC stands for. Conducting groundbreaking work, pushing boundaries and leading the way. In research, education, and healthcare. We are practical people with a high level of expertise, working hard to improve and renew the healthcare of today and the public health of tomorrow.
The Erasmus MC is an internationally recognized center for high-quality, compassionate care, highly rated transfer of knowledge and high-quality knowledge development in the fields of illness and health. The TransPot consortium consists of European academic and private sector research groups from The Netherlands, UK, Germany, Finland and Greece. Besides an extensive training programme with frequent meetings and workshops, yearly secondments to various partners are scheduled during the course of the project.
The candidate will be a member of the Experimental Urological Oncology research group of the Department of Urology. The candidate will work within a research team that comprises researchers and technicians dedicated to prostate cancer research.
Additional information
For more information about this position, please contact Dr. Wytske van Weerden, projectmanager by e-mail:
w.vanweerden@erasmusmc.nl.
If you are excited by the thought of this position and would like to apply, please do so by using the application button. Goedgekeurd Ja
15.11.2017 | Ajankohtaista
The Faculty of Medicine at the University of Helsinki conducts high-quality research and provides research-based basic and post-graduate education in medicine and dentistry, psychology and logopedics. The Faculty of Medicine at the University of Helsinki is located in the Meilahti-Ruskeasuo Campus, offering excellent opportunities for close collaboration with both the University Hospital and public sector research institutes (the National Institute of Health and Welfare, the Finnish Institute of Occupational Health).
Research Programs Unit of the Faculty of Medicine is a top-quality research environment. Unit’s five research program comprises groups that integrate clinical, translational and biomedical research.
The Tumor Genomics Research Group at the University of Helsinki’s Faculty of Medicine, is one of the largest biomedical research groups in Finland with a 30-member research team, including biologists, computer scientists and medical doctors. The group focuses on understanding the causes and mechanisms of tumorigenesis, particularly in uterine leiomyoma and colorectal cancer. Here, researchers are given the opportunity to work in an internationally acclaimed research environment and good working atmosphere. The group offers the availability of state-of-the-art facilities, equipment, and bioinformatic resources for high-throughput analyses. The work has led to publications in journals such as Science, Nature, and New England Journal of Medicine.
The group is part of the Academy of Finland funded Center of Excellence in Tumor Genetics (CoETG) with a special focus on understanding the interplay between genetic and environmental signals leading to neoplasia.
We are currently seeking an outstanding candidate for a
GRADUATE STUDENT & POST-DOCTORAL RESEARCHER POSITION
The open positions are in the fields of cancer genetics, systems biology and bioinformatics research.
More information and application
Closing date for applications is 30.11.2017.
14.11.2017 | Ajankohtaista
Saimme nauttia työelämäseminaarissamme erilaisista solubiologian alaan liittyvistä esityksistä. Lisäksi opiskelijoilla oli mahtava mahdollisuus kysyä lisätietoa puhujiltamme rennosti viinin ja snacksien lomassa esitysten jälkeen. Lisäksi jaoimme ensimmäistä kertaa Aktiivisen yhdistystoiminnan stipendin sekä Hyvä gradu -stipendin. Seminaariosallistujien kesken arvottiin upea Katri Kallion bakteriofaagi-maalaus.
Anette Iso-Mustajärvi Blueprint Genetics:iltä toi seminaariin yritysnäkökulmaa ja muistutti opiskelijoita myös opintojen aikaisten töiden ja suhteiden tärkeydestä työnhaussa.
Pasi Kankaanpää Turku Bioimaging:ilta kertoi monipuolisesta työstään ja kuvantamisen tarjoamien työmahdollisuuksien tärkeydestä tulevaisuudessa.
Hedelmöityshoitobiologin puheen piti Elisa Lehtilahti Felicitas Mehiläiseltä.
Jaoimme ensimmäistä kertaa Aktiivisen yhdistystoiminnan stipendin sekä Hyvä gradu -stipendin. Syrinx ry:n hallituksen ja professori Janne Ihalaisen suositusten perusteella yhdistystoiminnan stipendi annettiin Elisa Salmivirralle ja gradustipendi Johanna Matilaiselle.
Arvontaa Katri Kallion bakteriofaagi-maalauksestasuoritetaan.
Katri Kallion upea bakteriofaagi-maalaus saatin vihdoin arvottua onnekkaalle opiskelijalle.
Puheiden jälkeen vietimme rennon viini&snacks -tilaisuuden bio- ja ympäristötieteiden laitoksen Tumassa.
Seminaariimme osallistui runsas määrä opiskelijoita, joista suurin osa jäi myös Tumaan keskustelemaan puhujien kanssa varsinaisten esitysten jälkeen.
Työelämäseminaarin puhujat Johanna Matilainen, Elisa Lehtilahti, Pasi Kankaanpää, Anette Iso-Mustajärvi, Marjukka Friman ja Mira Ahinko.
Työelämäseminaarin puhujat, stipendien saajat sekä paikalla olleet Suomen Solubiologit ry:n hallituksen jäsenet.
Paikalla olleet Suomen Solubiologit ry:n hallituksen jäsenet: Johanna Matilainen, Elina Siljamäki, Mira Ahinko, Jan Koski, Linda Kauppinen ja Anne-Mari Koivisto.
14.11.2017 | Ajankohtaista
Postdoctoral fellowships are available in the laboratory of Dr. Suneel Apte to investigate the proteomics and biology of cardiovascular development and disease. These positions will suit recent PhDs, MD/PhDs, or MDs with a career interest in proteases, extracellular matrix, proteomics, mouse genetics, cardiovascular disease, and systems biology. We offer an excellent opportunity for mass spectrometrists seeking to develop expertise in disease biology and biologists seeking expertise in proteomics and bioinformatics.
The research project will involve the following:
1. Proteomics of cardiovascular tissues.
2. Cardiovascular disease, specifically, aortic aneurysms, valve diseases.
3. Degradomics to identify substrates of ADAMTS proteases.
4. Developmental biology using mouse models.
5. Systems biology.
6. Matrix biology, cell-matrix interactions, and biology of vascular smooth muscle cells.
Applicants must be highly motivated, energetic, well-organized, and independent, with a well-developed ability and the appropriate temperament to work amicably and collaboratively within a multidisciplinary team. A strong work ethic, integrity, and professionalism are expected. Exceptional writing skills and a track record of relevant publications are preferred. Fellows will join a laboratory with expertise in mouse genetics, developmental biology, biochemistry, and cell biology (www.lerner.ccf.org/bme/apte/). Proteomics will utilize Orbitrap Fusion Lumos Tribrid and Orbitrap Elite LTQ mass spectrometers in the Lerner Research Institute’s Proteomics Core (Director: Belinda Willard, PhD).
The Lerner Research Institute (www.lerner.ccf.org/) is a large, leading biomedical research institute with diverse research activities, a strong academic program with local universities, a medical school and outstanding core facilities. The Cleveland Clinic (https://my.clevelandclinic.org/) is internationally recognized for treatment of cardiovascular disease. Cleveland is an affordable, medium-sized city with a wealth of cultural and outdoors opportunities.
Interested applicants should submit:
· A letter of application
· Complete curriculum vitae
· 1- to 2-page statement of research/career goals
· Contact details of three references with intimate knowledge of their work
Send the above materials and direct any inquiries to:
Suneel S. Apte, MBBS, DPhil
Department of Biomedical Engineering / ND20
Cleveland Clinic
9500 Euclid Avenue
Cleveland, OH 44195
14.11.2017 | Ajankohtaista
https://careers.blueprintgenetics.com/jobs/56603-geneticists
Introduction
Blueprint Genetics is on a mission to bring world-class genetic knowledge to mainstream healthcare. To meet the challenges imposed by our rapid growth, we are looking for new Geneticists to join our Clinical Interpretation Team. We are a team of experienced professionals with diverse backgrounds who share the passion for helping patients and families suffering from inherited disorders. Our constantly evolving diagnostic portfolio currently includes over 400 tests that cover a wide variety of clinical specialties and diagnostic approaches, including Whole Exome Sequencing. We work with hundreds of clinics around the globe and the quality of our interpretation has been praised by many of the world’s best medical centers. If you have the ambition to be among the pioneers of the molecular era of medicine, you might be the person we are looking for.
Job description
The position involves interpretation and reporting of findings from our clinical molecular genetic tests, including panel-based tests, targeted family member tests and others. Our Geneticists also participate in the development and validation of products and applications in a project team environment. Those interested get to collaborate with our Software Engineers and Data Scientists with the development of our proprietary software tools that enable us to interpret identified variants efficiently by utilizing artificial intelligence and machine learning.
Qualifications
Education:
- Clinical Laboratory Geneticist degree; or
- Board certification in Clinical Molecular Genetics / Laboratory Genetics and Genomics; or
- Ph.D. in Genetics.
Experience and skills:
- Experience in interpreting and reporting genetic test results in a clinical setting utilizing NGS, Sanger sequencing and other methods.
- Knowledge of current genomic information and variant databases is essential.
- Experience in working under certified and accredited quality management systems is an asset.
- Fluent skills in oral and written English are a necessity.
Personal attributes:
- Great attention to detail
- Critical thinking when reviewing scientific literature
- Effective planning and organization skills
- Excellent follow-through abilities
- Fitting the immediate, low-hierarchy and positive Blueprint culture
What we offer
At Blueprint Genetics, you get to be a valued part of our global and multidisciplinary team of people who want to make a difference. You will be working daily to bring your expertise from base pairs to bedside for improved patient outcomes. We offer you a rapidly evolving working environment where you can learn and grow together with a unique company and great colleagues. You get to use everything you have learned in an environment that is unlike anything you have experienced before.
Inquiries about the position can be sent to Clinical Interpretation Team Leader Dr. Eveliina Salminen at eveliina.salminen[at]blueprintgenetics.com
