24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/doctoral-researchers-molecular-medicine-and-life-sciences-1-2169799?source=job_alert&utm_source=job_alert&utm_medium=email&utm_campaign=job_alert&utm_content=job_title
The Institute for Molecular Medicine Finland (FIMM) at the University of Helsinki invites applications for the positions of
Doctoral Researchers in Human Genomics and Complex Disorders
We currently have 2 openings for doctoral researchers starting in October 2024 or as agreed. The appointed doctoral researchers will be supervised by Docent Rubina Tabassum.
We are seeking highly motivated doctoral researchers to work in the field of human genomics, with particular focus on lipidomics and metabolomics. The planned PhD project will focus on understanding the metabolic heterogeneity in complex disorders using integrative omics approach to provide better understanding of the complex disorders, new biomarkers, and potential approaches for targeted therapies. We utilize large-scale biobanks data including health data, genomics, lipidomics and metabolomics; and employ diverse computational and statistical tools to carry out integrative research to understand the complex interplay between metabolism and health.
WHAT WE OFFER
- A fully funded 4-year PhD student position at the FIMM, University of Helsinki.
- An exciting opportunity to conduct impactful research in a supportive and stimulating environment.
- Exceptional scope for collaboration, with a planned research visits with leading research groups in the field.
- Plenty of opportunities to attend international conferences to build your scientific network.
- Access to top-notch resources and excellent support to further learning and professional development.
YOUR PROFILE
- A highly motivated student with a second cycle academic degree (MSc, MD or equivalent) in biology, biochemistry, bioinformatics, biotechnology, computer science, genetics, medicine, statistics or other related fields.
- Experience in programming (e.g., R or Python) and statistical analysis of scientific data.
- Strong analytical and quantitative skills with problem solving and troubleshooting aptitude.
- Excellent written and oral communication skills in English, and ability to work independently as well as in an international team.
The appointee should either already have the right to pursue a doctoral degree at the University of Helsinki by the start of the appointment or apply for the right and obtain it within the probationary period of six months of their appointment, please see: https://www.helsinki.fi/en/research/doctoral-education/the-application-process-in-a-nutshell
HOW TO APPLY
Candidates are invited to apply using the University of Helsinki Recruitment System and are requested to enclose the following documents in English as a single PDF file:
- Cover letter (max. 1 page) detailing motivation, research interests and experience.
- Curriculum vitae (max. 3 pages including publications) with contact information of two persons for references
- Copies of Master’s, and Bachelor’s degree certificates and official transcripts of the records, and their translations, if the originals are not in Finnish, Swedish or English.
External applicants should submit the application using the ’Apply Now’ button below.
Internal applicants (i.e., current employees of the University of Helsinki) may submit their applications by using the ”Employee Login” button.
The closing date for application is Sep 16, 2024 at 23:59 Eastern European Time. We will process applications already during the application period and the position will be filled as soon as suitable candidates are found.
Please note that applications submitted after the deadline, incomplete or failing to meet the requirements will not be considered.
We value a diverse, equitable, and inclusive work environment. All qualified applicants will receive consideration for the position, without regard to race, colour, religion, gender, gender identity or expression, sexual orientation, origin, genetics, disability, or age.
SALARY AND BENEFITS
The salary is based on the job requirement scheme for teaching and research staff according to the salary system of the Finnish universities. In addition, the appointee will be paid a personal salary component. In total, the starting gross salary of a doctoral researcher is typically around 2500 EUR per month and rises gradually as the PhD work progresses based on the University of Helsinki salary scheme.
The University of Helsinki provides its staff with occupational health and support for sports services as well as professional development opportunities. More information about the employee benefits at the University of Helsinki can be found at (https://www.helsinki.fi/en/about-us/careers/why-university-helsinki/staff-benefits).
FURTHER INFORMATION
24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/medical-scientific-liaison-msl-suomen-myynti-ja-markkinointi-orion-oyj-espoo-2164385?source=job_alert&utm_source=job_alert&utm_medium=email&utm_campaign=job_alert&utm_content=job_title
Haemme Orionin kaupallisiin toimintoihin Espoon toimipisteeseen lääketieteellistä biologisten valmisteiden, biosimilaarien sekä ihotautien asiantuntijaa Medical Scientific Liaison (MSL) vakituiseen tehtävään.
Tehtävän kuvaus
Toimit Orionin Suomen kaupallisten toimintojen lääketieteellisenä asiantuntijana biologisten valmisteiden, biosimilaarien sekä ihotautien parissa. Teet tiivistä ja rakentavaa yhteistyötä alan asiantuntijoiden sekä orionilaisten kollegoidesi kanssa.
Keskeiset vastuualueesi ja tehtäväsi:
- Biologisten valmisteiden, biosimilaarien ja ihotautien lääketutkimuskenttään perehtyminen
- Toimintasuunnitelman (medical plan) luominen ja toteuttaminen
- Ulkoisen asiantuntijaverkoston rakentaminen ja ylläpitäminen
- Alan tapahtumiin ja messuille osallistuminen
- Asiakaskysymyksiin vastaaminen yhteistyössä tuotepäällikön ja tuotespesialistien kanssa
- Markkinointiviestinnän ja -materiaalin tarkastaminen sekä hyväksyntä
- Myyntitiimin koulutus ja sparraaminen tieteellisestä näkökulmasta
Toimit tehtävässä tiiviissä yhteistyössä Orionin Medical Team Finlandin, myynnin johdon sekä tuotepäälliköiden kanssa. Toimenkuva on uusi ja pääset omalta osaltasi vaikuttamaan tehtävän kokonaisuuteen sekä painopistealueisiin.
Yksikön kuvaus
Suomessa Orion on markkinajohtaja lääkkeiden sekä apteekissa myytävien itsehoitovalmisteiden myynnissä. Suomen myynti- ja markkinointiorganisaatio edistää ihmislääkkeiden ja itsehoitovalmisteiden myyntiä pääkohderyhminään apteekit, kuluttajat, hoitajat ja lääkärit.
Tarjoamme
- Laajan, monipuolisen ja itsenäisen tehtäväkokonaisuuden erikoislääkäreiden parissa
- Orionin globaalin lääketieteellisen asiantuntijaverkoston tuen
- Monipuoliset tuotteet ja mahdollisuuden olla mukana uusien alkuperävalmisteiden lanseerauksessa
- Mukavan, energisen ja huipputuloksia tekevän lähitiimin sekä Suomen johtavan lääkemyynti- ja markkinointiorganisaation tuen
Orionilla arvostamme toisiamme, tavoittelemme parasta ja rakennamme yhdessä huomista – tervetuloa rakentamaan hyvinvointia kanssamme!
Tutustu tarkemmin Orioniin työnantajana yrityksemme internetsivuilta Orion työnantajana
Edellytämme
- Lääketieteellinen, farmaseuttinen tai luonnontieteellinen koulutus, min. ylempi korkeakoulututkinto
- Aikaisempaa kokemusta asiantuntijamyynnistä tai key opinion leader management työstä
- Kyky tieteellisen materiaalin omaksumiseen ja oleellisen tiedon löytämiseen
- Erinomaiset kirjalliset ja suulliset kommunikointitaidot suomeksi ja englanniksi
- Matkustusvalmius kotimaassa ja satunnaisesti ulkomailla
Olet arjen haasteista ja kiireistä energiaa imevä tiimipelaaja, joka nauttii monimuotoisesta huippuasiantuntijan työnkuvasta. Työskentelet luontevasti sekä asiakkaiden että sisäisten ja ulkoisten sidosryhmien kanssa, ja sinulla on hyvät yhteistyö-, neuvottelu- ja esiintymistaidot. Haluat myös syventyä itsenäisesti tieteellisten artikkelien ja katsausten pariin. Osaat käyttää ja hyödyntää moderneja työvälineitä päivittäisessä työssäsi.
Lisätietoja
Kiinnostuitko tehtävästä? Odotamme hakemustasi mahdollisimman pian, kuitenkin viimeistään 28.8.2024 mennessä.
Lisätietoja tehtävästä antaa Anna-Kaisa Laine, lääketieteellinen asiantuntija, puh 050 9663149 to 15.8. klo 13-15, ti 20.8. klo 11-13 ja ke 21.8. klo 9-11.
#LI-Orion
Tehtävään valitulta henkilöltä edellytetään hyväksyttyä terveystarkastusta, joka sisältää myös huumausainetestauksen.
Meitä orionilaisia on 3600 yli 30 maassa ja työskentelemme hyvinkin erilaisissa tehtävissä. Joukostamme löytyy niin tutkijoita ja laborantteja kuin insinöörejä ja IT-asiantuntijoitakin sekä tuotantotyöntekijöitä ja monia muita. Tarjoamme työntekijöillemme monipuolisia sekä vastuullisia tehtäviä aidosti monialaisessa ympäristössä. Kannustamme oman osaamisen kehittämiseen ja tarjoamme mahdollisuuden vaikuttaa työtehtäviin ja oman urapolun luomiseen Orionilla. Me etsimme oman alansa huipputekijöitä, jotka jakavat aidon innostuksemme siihen, mitä teemme.
24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/asiantuntija-kudospankki-2163860?source=job_alert&utm_source=job_alert&utm_medium=email&utm_campaign=job_alert&utm_content=job_title
Tampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: [www.tuni.fi](https://www.tuni.fi/)
Haemme nyt kliinisen kudospankin tehtäviin asiantuntijaa. Tehtävä sijoittuu [Lääketieteen ja terveysteknologian tiedekunnassamme](https://www.tuni.fi/fi/tutustu-meihin/laaketieteen-ja-terveysteknologian…) toimivaan Regea kudospankkiin. Tehtävä on kokoaikainen ja se täytetään toistaiseksi voimassa olevana 1.11.2024 lukien tai sopimuksen mukaan.
[Regea kudospankki](https://www.tuni.fi/fi/tutustu-meihin/regea-kudospankki) ottaa talteen, käsittelee ja välittää kudoksia kliiniseen käyttöön. Toiminnassa noudatetaan laatujärjestelmää, jonka vaatimukset perustuvat kudoslakiin. Toimintaa valvoo Lääkealan turvallisuus- ja kehittämiskeskus Fimea.
Tehtäväkuvaus
Haemme asiantuntijaa Regea kudospankin tehtäviin. Tehtävänkuva käsittää esimerkiksi kudossiirteiden käsittelyä ja arviointia, puhdastilaympäristön mikrobiologista olosuhdevalvontaa, laadunhallintajärjestelmien kehittämistä ja ylläpitoa sekä laboratoriolaitteiden kvalifiointeihin liittyviä tehtäviä. Tehtävään kuuluu käytännön laboratoriotyötä, josta osa tehdään puhdastilassa. Tehtävään saa kattavan perehdytyksen.
Edellytykset
Tehtävään edellytetään soveltuvaa ylempää korkeakoulututkintoa, kuten luonnontieteiden FM tai vastaava. Tehtävän hoito edellyttää sujuvaa suomen ja englannin kielen taitoa. Eduksi katsomme kokemuksen laadunhallintajärjestelmistä sekä solu- tai kudosviljelystä. Tehtävän hoidossa korostuvat hyvät yhteistyötaidot, järjestelmällisyys ja itsenäinen työote.
Tampereen yliopisto on ainutlaatuinen, monialainen ja rohkeasti tulevaisuuteen katsova, kehittyvä yhteisö. Meille tärkeitä arvoja ovat avoimuus, kriittisyys, moninaisuus, oppijalähtöisyys, rohkeus, sivistys ja vastuullisuus. Toivommekin, että voit osaltasi sitoutua näihin arvoihin ja edistät niiden mukaista toimintaa omassa tehtävässäsi.
Tarjoamme
Kokoaikainen asiantuntijan tehtävä täytetään toistaiseksi voimassa olevana 1.11.2024 alkaen tai sopimuksen mukaan. Tehtävässä sovelletaan työsopimuslain mukaista koeaikaa.
Tehtävän palkkaus määräytyy yliopistojen yleisen työehtosopimuksen [muun henkilöstön palkkausjärjestelmän](https://www.sivista.fi/tyosuhdeasiat/tyoehtosopimukset-ja-palkkataulukot…)mukaisesti. Asiantuntijan tehtävässä alustava vaativuustaso on 9, minkä lisäksi maksetaan henkilökohtaiseen työstä suoriutumiseen perustuvaa palkanosaa. Aloittavan asiantuntijan tehtävän palkka on noin 3900–4100 euroa riippuen valittavan henkilön kokemuksesta.
Tarjoamme sinulle vastuullisen ja monipuolisen työtehtävän. Työssä sinua tukee esihenkilön lisäksi asiantuntevat ja ammattitaitoiset kollegat. Autamme sinua perehtymään työtehtäviisi ja pääsemään sujuvasti sisään työyhteisöömme.
Henkilöstöetuihimme kuuluvat mm. joustavat työskentelymahdollisuudet, liikunta- ja kulttuurietu, kattavat työterveyshuollon palvelut sekä ”tunti työajasta liikuntaan” etu. Työskentelemme joustavasti etänä ja Tampereen kaikilla kolmella kampuksella, joissa käytettävissäsi ovat edulliset ravintola- ja kahvilapalvelut.
Lue lisää työskentelystä meillä [työnantajasivuiltamme](http://www.tuni.fi/toihin). Tervetuloa innovatiiviseen työyhteisöömme luomaan merkityksellistä uraa sekä vaikuttamaan yliopistomme ja yhteisen kulttuurimme kehittymiseen.
Hakuohjeet
Jätäthän hakemuksesi sähköisellä lomakkeella (linkki löytyy tämän ilmoituksen alta). Hakuaika tehtävään päättyy 3.9.2024 klo 23:59.
Liitä hakemukseesi PDF-muodossa:
– Ansioluettelo
– Vapaamuotoinen motivaatiokirje (1-2 sivua)
Hakuajan päätyttyä kutsumme soveltuvimmat hakijat haastatteluihin. Haastatteluiden lisäksi käytämme mahdollisesti ulkopuolisen palveluntarjoajan toteuttamia soveltuvuusarviointeja.
Lisätietoja tehtävästä antaa Tiia Tallinen p. 050 568 0428, tiia.tallinen@tuni.fi.
Jätä hakemus: https://tuni.rekrytointi.com/paikat/index.php?o=A_A&jid=2381&jbid=15
Työpaikan osoite: 33520
Työ alkaa: 01.11.2024
Työaika: Kokoaikatyö
Työn kesto: Toistaiseksi voimassa oleva
Hakuaika päättyy: 03.09.2024 20:59
Ilmoitus jätetty: 13.08.2024 12:30
Työmarkkinatorin ilmoitusnumero: b166659b-a4bd-466e-99c4-408a163eb09f
Lähde: Työmarkkinatorin asiakastietojärjestelmä
24.8.2024 | Avoimet työpaikat
https://jobs.helsinki.fi/job/Helsinki-Research-Coordinator/801146102/?feedId=360857
The Institute for Molecular Medicine Finland (FIMM) is an international research institute focusing on human genomics and personalised medicine at the University of Helsinki. In the beginning of 2017 FIMM joined the University of Helsinki’s new life science research centre, Helsinki Institute of Life Science HiLIFE, as an operational unit. FIMM integrates molecular medicine research, technology centre and biobanking infrastructures under one roof, promoting translational research in grand challenge projects, specifically, the impact of genome information from the Finnish population in personalised health and medicine, individualised cancer medicine, and digital molecular medicine. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.
FIMM is currently seeking a
Research Coordinator
for a fixed term of two years with a possibility of extension.
We are seeking a qualified and motivated Research Coordinator for national and international research projects of Human Genomics Unit at FIMM led by Professors Samuli Ripatti and Aarno Palotie.
Samuli Ripatti, PhD, is the Director of the Institute for Molecular Medicine Finland (FIMM), HiLIFE, Professor of Biometry at the Faculty of Medicine, University of Helsinki and at Massachusetts General Hospital and Broad Institute of MIT and Harvard. He is chairing the Academy of Finland Centre of Excellence in Complex Disease Genetics and EU H2020-funded Intervene Consortium. His research group studies genetic variation in the Finnish population and its effects on common complex disease risks and management. He is one of the pioneers in developing and testing the clinical translation of polygenic risk scores in disease prevention and early detection.
Professor Aarno Palotie, M.D., Ph.D. is the Research Director of the Human Genomics program at the Institute for Molecular Medicine Finland (FIMM), HiLIFE. He is also a faculty member at the Center for Human Genome Research at the Massachusetts General Hospital in Boston and an associate member of the Broad Institute of MIT and Harvard.
Prof. Palotie is the Scientific Director of the large FinnGen project (www.finngen.fi) that combines the genome and national health record data from 500 000 Finnish participants. He has chaired several large international research consortia, like the Sequencing Initiative Suomi, SISu (www.sisuproject.fi) combining all Finnish sequences for a data resource and variant catalogue, the SUPER project (www.superfinland.fi) collecting and studying genetics in over 10 000 Finnish psychosis patients, the International Headache Genetics Consortium (IHGC, www.headachegenetics.org) and the Northern Finland Intellectual Disability (NFID) study.
The candidate is expected to assist Professors Ripatti and Palotie and collaborating senior scientists at FIMM Human Genomics Unit to coordinate and manage the international research projects involved, for example, EU FP7/H2020 projects, NIH projects, the Academy of Finland Center of Excellence and other collaboration projects. Major tasks include monitoring project progress, liaising with financial and administrative staff, organizing and participating in project meetings, preparing reports and communicating with funding agencies and collaborators.
The successful candidate should hold a PhD degree with minimum two-years working experience, preferably in the field of life science related discipline. Experience in project coordination and management at international level (especially large-scale consortium management experience) is appreciated. The candidate should have fluency in written and spoken English (knowledge of Finnish or other European language will be an advantage), excellent organizational, communication and problem-solving skills, strong capability to work independently as well as cooperate harmoniously with administrative staff. The candidate should be available to travel abroad (occasionally and mostly within Europe).
This is a full-time position based in Biomedicum 2, Helsinki (www.biomedicum.fi), Finland, and is expected to start on October 1st, 2024 or earlier for an initial period of at least two years with a possibility of extension. A trial period of 6 months will be applied.
Salary will be based on the University salary scheme for research and teaching staff. The starting salary will be ca. 4,200 – 4,600 euros/month, depending on the appointee’s qualifications and experience and including a salary component based on personal performance.
To apply for the position, please send your motivation letter and CV, including list of publications and contact information for two references, through the University of Helsinki electronic recruitment system by clicking on the Apply link. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications through SAP Fiori https://msap.sap.helsinki.fi .
Please apply no later than September 6th. The employment may begin as soon as possible or as agreed.
For further information please visit our website at http://www.fimm.fi and/or contact Professors aarno.palotie(at)helsinki.fi, samuli.ripatti(at)helsinki.fi or Project coordinator sari.kivikko(at)helsinki.fi. Technical support regarding the recruitment system: rekrytointi@helsinki.fi.
24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/research-scientist-formulation-development-espoo-2164408
Description of position
We are looking for a research-driven and motivated formulation scientist with experience in advancing small molecule drug development projects. We operate within oncology and pain therapy areas.
Your main responsibility is to develop formulations for oral solid dosage forms. This includes for example planning and running studies exploring their feasibility and confirming their appropriateness for the intended use. You will review results, summarize and make conclusions of the studies, and document the work for registration purposes. The work includes regular hands-on laboratory work. As a key player in CMC team you will create forward-looking formulation strategies that enable the development of a high-quality drug product through the clinical phase into registration and launch. You also manage and organize development related tasks, thus the position involves intensive collaboration with internal and external stakeholders working closely together in multi-disciplinary teams.
This temporary (1 year) position is based in Espoo or Turku, Finland.
Description of unit
This position is situated in Clinical Product Development unit, which belongs to Pharmaceutical Sciences department within Orion Pharma Research and Development. Your peers are scientists working with formulation development, and chemical and physical analytics. We operate in project CMC teams to develop new drug products.
We offer
We offer a great team to join with skilled and highly motivated colleagues. Appreciation of colleagues and continuous development are part of our core values. We enable opportunities to utilize your skills and competencies widely as we continuously create something new.
Learn more about Orion as an employer on our website: https://www.orion.fi/en/careers/orion-as-an-employer/
Requirements
To succeed in this role, you possess the following:
- Master’s or preferably doctoral degree in pharmaceutical sciences or a related field
- Demonstrated skill in developing pharmaceutical oral solid dosage forms and manufacturing processes (granulation, tableting, etc.)
- Experience in application of QbD concept in design, execution, and interpretation of formulation and process development experiments
- Understanding of analytical characterization of formulations (chemical, physical and biopharmaceutical)
- Experience of working in a GMP-regulated environment preferred
- Ability to collaborate well in cross-functional teams internally and in external networks with academia, CROs and partners
- Experience in authoring regulatory submissions
- High degree of professionalism, ethics and integrity
- Excellent presentation and written/verbal communication skills in English
Personal qualities we are looking for are:
- Strong organizational skills and attention to detail
- You are a doer and have an accurate working style
- Forward thinking mindset with the ability to manage multiple projects, and identify and resolve issues.
- Motivated to learn
Additional information
If you are interested in this opportunity, please apply by 1st of September 2024. We may process applications already during the application period, so please submit your application and CV as soon as possible.
If you have any questions, please contact Head of Clinical Product Development Satu Lakio Tel. +358 50 9664422 on Mon 19th of Aug at 14.00 – 15.00 or Fri 30th of Aug at 14.00 – 15.00 (EET).
#LI-ORION
Approved medical examination which also includes drug testing is required prior to the employment.
Orion Corporation operates in more than 30 countries, where we Orionees, 3600 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.
24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/production-specialist-downstream-processes-2165122?source=job_alert&utm_source=job_alert&utm_medium=email&utm_campaign=job_alert&utm_content=job_title
We are happy to announce opening of a new vacancy in Production department – Production Specialist, downstream processes:
Requirements:
- Education – degree in biochemistry/biotechnology/immunology or relevant field (M.Sc, B.Sc, B.Eng)
- Knowledge and practical experience of basic biochemical and/or immunochemical methods.
- Preferably 3 years of experience working with antibodies and/or antigens in a biotech/pharma company.
- Experience in affinity chromatography and/or lyophilization.
- Problem solving and analytical skills.
- Teamwork skills.
- Fluent written and spoken English.
- Knowledge of LIMS is an advantage.
- Knowledge of ISO 9001:2015 and/or GMP is preferable.
Job duties:
- Performing manufacturing tasks related to antibody downstream manufacturing processes in accordance with the production plan.
- Performing manufacturing task related to other biological materials.
- Working in accordance with appropriate SOPs, maintaining quality standards.
- Keeping logs to ensure full traceability of the materials and reproducibility of the procedures.
- Informing about possible deviations from established procedures or routines, participating in problem solving.
- Compliance with workplace safety requirements.
- Work is 100% onsite.
24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/bioprocess-technician-research-and-development-2166445?source=job_alert&utm_source=job_alert&utm_medium=email&utm_campaign=job_alert&utm_content=job_title
Are you interested in revolutionizing the food system by producing sustainable food ingredients with cutting edge technology and with superb colleagues who are top experts in their field? Onego Bio might be just the place for you.
Onego Bio is a Finnish leading food-biotech company producing animal-free egg protein with precision fermentation. The company’s award-winning technology has placed them at the forefront of the industry, having cracked the code to producing bioidentical egg proteins that provide the same taste, functionality, and nutrition but without the poor efficiency and harmful impacts of animal agriculture. Onego Bio is launching its first product Bioalbumen® as an ingredient for the food industry and transforming the food system to meet the urgent sustainability requirements of the world. The company is focused on scaling precision fermentation to industrial scale with the superior Trichoderma reesei production platform.
Founded by alternative protein pioneer Maija Itkonen (CEO) and precision fermentation trailblazer Christopher Landowski (CTO), Onego Bio is a spin-off that salutes the remarkable work done by VTT Technical Research Centre of Finland for the next level cellular agriculture products and applications. In April 2024 Onego raised a $40M Series A funding round (one of the largest in the Nordics) for fueling scale up and go-to-market in the US. Similarly, in July 2024 Onego secured €14M / $15.2M new funding from the European Innovation Council (EIC) Accelerator Program and additional Series A investors. In 2024 Onego Bio has successfully raised altogether €50.5M / $55M, bringing the company’s total funding to € 65M / $70.8M. Since launching, the company has received massive international recognition, including being selected as a winner of Fast Company’s 2023 World Changing Ideas Awards. Onego Bio is a founding member of Precision Fermentation Alliance US and Food Fermentation Europe. Get to know us better by exploring our webpage www.onego.bio/about-us
We are now looking for a talented bioprocess technician to join our R&D team in Helsinki, Finland.
In this position, you will play an essential role in supporting research projects with a bioprocess team and contribute towards our greater goal of providing animal-free egg protein ingredients to the world. We aim to play a significant role in building the sustainable food system with the help of our partners throughout the world. Towards this goal our team utilizes microbial production systems for expressing egg white proteins using filamentous fungi.
Your responsibilities as Bioprocess technician:
- Supporting bioprocess team by carrying out laboratory work including solution preparation, bioreactor preparation, cultivation experiments, sampling and sample handling, different steps of downstream processing and equipment cleaning and sterilization both in laboratory and pilot scale
- Analysis of bioprocess samples, for example hplc, SDS-PAGE and other protein analytics (Bradford)
- Keeping an electrical lab notebook and reporting results to scientists
- Help maintaining the research lab facilities and instruments
We are looking for a person who has:
- Completed Bachelor´s degree from University of Applied Sciences or technician´s degree preferably in laboratory or process technology
- Experience with solution and media preparation and use of autoclave
- Basic knowledge of bioprocess technology, fermentation, and aseptic working techniques
- Eager attitude towards your working tasks and learning new things
- Ability to prioritize and execute simultaneous tasks
- Sufficient English language skills to document results and follow working instructions
As a person, we hope that you are:
- Skilful and precisely plan and conduct your lab work and follow lab safety protocols and you can schedule your own work between multiple tasks
- Self-motivated and willing to take the initiative to get things accomplished
- Have effective communication skills
- Work well with other team members and contribute to a good working environment
- Can tolerate pressure and maintain a good work-life balance
- Available for flexible working hours also: the working hours are mainly among 7,5 h daily work, but if necessary, you can flexibly work outside the office hours
- Capable to work with physically heavy loads
- Are flexible to take on a variety of tasks anticipated in a start-up company
With Onego Bio, you’ll enjoy: / What we offer you:
- Molecular biology with an impact. Onego Bio is transforming the future of egg production by creating cutting-edge microbial protein production systems. Microbial production technology to produce egg white protein can significantly mitigate environmental impacts according to the LCA study published in Nature Food. The positive impact of our technology does not only contribute positively on the environment but also supply chain stability, global health, food security and animal welfare. Egg is one of the world’s most popular proteins and our team stands to meet the demand in a way that preserves the future of our planet.
- Superb colleagues. We offer working in a passionate environment within a fun and diverse team who want to make an impact in the world. With Onego Bio, you will join a dedicated group of top experts in their respective fields who foster a culture of trust, openness, and sharing ideas.
- Competitive salary. We want to attract the best people, so we will provide competitive salaries.
- Nordic work–life balance. Working in Finland, the happiest country in the world, enables a high quality of life. At Onego Bio, we make our people’s well-being a priority. We offer 6 weeks paid vacation a year, among other benefits including extended occupational healthcare, and exercise and culture benefits
Apply now and join our community of brilliant minds!
Please send your CV and application letter as soon as possible but at the latest by 8th of September 2024. We will process applications as they come in and fill the position as soon as we find the right candidate.
Interested and want to hear more?
For further information, please contact Elviira Kärkkäinen, Head of Bioprocessing, elviira.karkkainen@onego.bio.
Read more about our past work on the topic:
We look forward to hearing from you!
24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/doctoral-researcher-field-controlling-gene-transcription-cyclin-dependent-kinases-2166688?source=job_alert&utm_source=job_alert&utm_medium=email&utm_campaign=job_alert&utm_content=job_title
Faculty of Medicine, Barborič laboratory, invites applications for a position of
Doctoral Researcher
in the field of Controlling Gene Transcription by Cyclin-dependent Kinases and their Targeting in Cancer for a fixed-term.
The University of Helsinki is a research-oriented university which offers a stimulating and international environment. The Faculty of Medicine of the University of Helsinki, together with Helsinki University Central Hospital, The Helsinki Institute of Life Science, and the Institute for Molecular Medicine Finland forms the Academic Medical Center Helsinki. This medical campus ranks among the 10 best medical centers at European level and the 50 best centers in the world. More info on the Faculty or Medicine and AMCH can be found here: https://www.helsinki.fi/en/faculty-of-medicine and https://www.helsinki.fi/en/meilahti-campus
The lab’s mission is to unravel fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in essential and biomedically important transcriptional cyclin-dependent kinases (tCDKs) that trigger release of Pol II from promoter-proximal pausing and facilitate productive Pol II elongation along genes. We aim to exploit the knowledge on basic principles of gene regulation to help devise novel treatments of many diseases that stem from misregulated gene transcription programs. More information about the lab, including the latest research and news, can be found here: https://www.helsinki.fi/en/researchgroups/center-for-gene-regulation
We are looking for a creative thinker with strong analytical skills and a passion for science. We expect you to formulate your own hypotheses, propose experimental design to address them, and take advantage of the laboratory/research community’s intellectual and skill resources to advance the knowledge of the field. The competitive candidate should hold an MSc degree in molecular biology, biochemistry, biotechnology or related fields. Expertise in biochemistry and molecular biology is a pre-requisite for the position. In addition, we appreci-ate fluency in the analysis of NGS data. Strong command in written and spoken English is required.
The appointee must apply, and obtain, the right to pursue a doctoral degree at the University of Helsinki within the probationary period of 6 months: https://www.helsinki.fi/en/admissions-and-education/apply-doctoral-programmes/how-apply-doctoral-education. More info on The Doctoral Programme in Biomedicine and The Doctoral Programme in Integrative Life Science can be found here: https://www.helsinki.fi/en/research/doctoral-education/doctoral-schools-and-programmes/doctoral-school-in-health-sciences.
The successful candidate will receive training in biochemical, molecular biology and cell line-based functional assays, as well as cutting-edge systems biology methods, such as CRISPRi and nascent transcriptomics methods. The training will be furthered by research visits as part of our collaborations with a network of well-regarded laboratories around the globe. Current projects in the lab funded by the 4-year Research Council of Finland grant, 3-year Sigrid Juselius Foundation grant and Cancer Foundation Finland grant, Sigrid Juselius Foundation revolve around fundamental biology of tCDKs and their combinatorial targeting in cancer.
The salary of the selected candidate will be based on the University’s salary scheme for teaching and research personnel composed of task specific and personal performance components. A trial period of six months will be applied.
The University of Helsinki offers comprehensive services to its employees, including occupational health care and health insurance, unemployment and pension fund, a generous holiday package, sports facilities, and opportunities for professional development: https://www.helsinki.fi/en/about-us/careers.
The appointee is expected to reside in Finland while employed by the University of Helsinki. International staff is supported in relocating to Finland: https://www.helsinki.fi/en/about-us/careers/welcome.
Please submit your application, together with a motivation letter including a summary of your research interests, CV, and two letters of reference, through the University of Helsinki electronic recruitment system by clicking on the ’Apply now’ button.
Internal applicants (i.e., current employees of the University of Helsinki) submit their applications by using the Employee Login button.
The University of Helsinki welcomes applicants of any gender, linguistic and cultural background or minority group.
The closing date for application is September 9th, 2024. The shortlisted candidates will be notified about the interview shortly afterwards.
For further information, please contact Matjaž Barborič, Ph.D.; matjaz.barboric(at)helsinki.fi
Recent publications:
Wang Z et al. (2023) Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release. Nucleic Acids Res 51(20):10970-10991
Wang Z et al. (2023) P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway. Nucleic Acids Res 51(4):1687-1706
Bugai A et al. (2019) P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress. Molecular Cell 74(2): 254-267
24.8.2024 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3992495515
About the job
The University of Oulu is a multidisciplinary, international research university, with about 3,600 employees who produce new knowledge based on high-standards research and provide research based education to build a more sustainable, smarter, and more humane world. The University of Oulu community has about 17,000 people in total. Our northern scientific community operates globally and creates conditions for the emergence of innovations.
We are now seeking for a highly motivated and talented
Doctoral Researcher in Computational Cancer Biology
to join the education pilot in precision cancer medicine (iCANDOC) in the research group of Associate Professor Valerio Izzi at the University of Oulu.
In this position, you will participate in the national 1000 doctorates pilot programme which supports the completion of a doctoral degree within three years. As a partner in the programme, the University of Oulu is dedicated to ensuring you have a carefully planned and guided doctoral research experience which will be tailored to support your career plans, enabling you to continue into demanding expert positions in the changing job markets in industry, the public sector and academia.
Job Description
Cancer initiation and progression depend on the interplay between heterogeneous tumor cells and the surrounding tumor microenvironment (TME), consisting of various types of stromal cells and the extracellular matrix (ECM). Our research focuses on understanding the composition and roles of tumor ECM compartments (niches) in modulating cancer cell phenotypes and fates, cancer progression and therapy resistance, at the systems biology level.
The Izzi group (https://github.com/Izzilab) is a leader in developing computational tools for the analysis of ECM in high-dimensional, multi-modal data. As a doctoral researcher in our group, you will participate in developing machine learning/AI algorithms to deconvolute the connections between ECM niches and functional cancer cell states at the single-cell, spatial, and proteomics level. Expectedly, these algorithms will help identifying druggable ECM targets in cancer, which will be validated in our cellular and in vivo cancer models.
As a member of our group, you will access a network of numerous national and international collaborations, which will expose you to state-of-the-art methodologies for ECM research and offer rich opportunities for internships, mobility, and further career development after completion the PhD in three years. The Izzi group is part of the ECM-Hypoxia research unit with six internationally strong research groups.
Who are you?
In order to succeed and enjoy the position, we expect from you:
- Master’s or equivalent degree in bioinformatics, biostatistics, data analysis, molecular and cell biology, biochemistry, biomedicine, medicine, or related fields
- Excellent command of R and/or Python and advanced knowledge of machine learning and deep learning
- Experience with big data analysis (bulk and single-cell RNASeq, proteomics, spatial methods are considered an advantage)
- Basic knowledge of cancer cell biology
- Fluent in written and spoken English language
- Excellent communication and teamwork skills
- Full dedication on the research project and ability to meet project deadlines
We also appreciate
- Previous experience in teaching
- Experience with Shinyapp development
- Experience with cell culture and wet lab-based cancer research projects
- Please see also the requirements of the University of Oulu Graduate School (UniOGS).
Qualification Requirements
The chosen doctoral researchers will also be expected to apply for doctoral study rights at the University of Oulu Graduate School. Eligibility for study rights will be evaluated during the job application process. We are looking for excellent candidates who must fulfill the following criteria:
- Must hold a master’s degree or equivalent degree (e.g. licentiate) in bioinformatics, biostatistics, data analysis, molecular and cell biology, biochemistry, biomedicine, medicine, or related fields
- Undergraduate students are eligible to apply provided their Master’s or equivalent degree is finished by 1.1.2025
- Must have achieved a good grade in their degree (i.e. at least 60 % of the maximum grade in both taught courses and the master’s thesis)
- Must be able to demonstrate English language skills that are sufficient to follow doctoral studies.
What We Offer
- A dynamic research environment which promotes personal and professional growth as a scientist The support of two experienced, enthusiastic and multidisciplinary research teams.
- A low hierarchy structure focused on teamwork and constant discussion flow.
- An inspiring international research atmosphere and smooth entry to national and international ECM research networks.
- Structured, interdisciplinary doctoral training.
- Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
- Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits.
- Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu.
- We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
- Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.
Position and salary
Doctoral researchers selected in the pilot programme will by default be offered a three-year (36 month) fixed-term full-time employment contract by University of Oulu. These positions are available for highly motivated and talented researchers wishing to undertake and complete training for a research-focused doctoral degree, starting 1.1.2025 at the earliest. The selected applicants are expected to start their project no later than 1.2.2025. A six-month trial period is applied in the position.
The salary of the selected doctoral researchers will be paid monthly. The salary will be based on the levels 2-4 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 2500-2800 € per month (before taxes).
The employment contracts are based on a total working time of 1612 hours per year, which gives the doctoral researchers freedom to plan their working hours.
How To Apply
Applications, together with all relevant enclosures, should be submitted using the electronic application form by 30.9.2024 (23:59 Finnish local time). The application should be written in English and include the following:
- Certificates/Diplomas Scanned copy of the original relevant Master’s degree certificates and transcript of records and, when necessary, official translations to Finnish or English.
- A motivation letter (max. 2 pages) summarizing applicant’s professional experience and expertise and describing why the applicant is a good fit for this position. Also, information on personal research interests, experience and career plans are valuable to provide here.
- Curriculum vitae (max. 2 pages). A recommended CV template can be found on the Finnish National Board on Research Integrity. At the end of the CV, the applicant must include a list of peer-reviewed scientific publications with full reference details. The number of pages of the publication list doesn’t concur to the max. 2 page-limit of the CV.
- Research plan (max. 4 pages) The research plan should mostly contain information about the planned use of algorithms (which? why? how?) to tackle the research questions mentioned in the Job Description section. The ability to envision how the use of such methodologies could advance the study of ECM niches in cancer is considered an advantage. Applicants to this position are encouraged to contact Prof. Valerio Izzi and Dr. Ritva Heljasvaara before and/or while preparing this document.
- A valid certificate or other demonstration of language proficiency.
Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Applications received after the call deadline will not be considered.
We welcome applicants from all backgrounds, including people of different ages, genders, and linguistic, cultural, or minority groups.
Evaluation
Applications will be evaluated according to the suitability of the candidate and the proposed research plan for the job description, competence, motivation, commitment and career plan. Applicants with excellent records in these areas will be invited to an online interview where the above criteria as well as professional experience and language proficiency will be reviewed. All candidates will be scored jointly by Prof. Valerio Izzi and Dr. Ritva Heljasvaara and the best candidate will be offered the position. All applicants will be informed at the different steps of the process.
Further information
For further information, please contact Valerio Izzi (valerio.izzi@oulu.fi) or Ritva Heljasvaara (ritva.heljasvaara@oulu.fi)
Työsopimuksen voimassaolo: määräaikainen yli 6 kuukautta | Työsuhteen luonne: kokoaikainen | Paikkojen lukumäärä: 1 | Työllisyysaste: 100 % | Paikkakunta: Oulu | Maakunta: Pohjois-Pohjanmaa | Maa: Finland | Ilmoitusnumero: 2024/305 | Yhteys: Ritva-Leena Heljasvaara , | Julkaistu: 2024-08-05 | Haku päättyy: 2024-09-30
24.8.2024 | Avoimet työpaikat
https://www.jobly.fi/tyopaikka/postdoctoral-researcher-field-controlling-gene-transcription-cyclin-dependent-kinases?source=job_alert&utm_source=job_alert&utm_medium=email&utm_campaign=job_alert&utm_content=job_title
Faculty of Medicine, Barborič laboratory, invites applications for a position of
Postdoctoral Researcher
in the field of Controlling Gene Transcription by Cyclin-dependent Kinases and their Targeting in Cancer for a fixed-term.
The University of Helsinki is a research-oriented university which offers a stimulating and international environment. The Faculty of Medicine of the University of Helsinki, together with Helsinki University Central Hospital, The Helsinki Institute of Life Science, and the Institute for Molecular Medicine Finland forms the Academic Medical Center Helsinki. This medical campus ranks among the 10 best medical centers at European level and the 50 best centers in the world. More info on the Faculty or Medicine and AMCH can be found here: https://www.helsinki.fi/en/faculty-of-medicine and https://www.helsinki.fi/en/meilahti-campus
The lab’s mission is to unravel fundamental mechanisms that control the elongation phase of transcription by RNA polymerase II (Pol II) in normal and disease states. We are particularly interested in essential and biomedically important transcriptional cyclin-dependent kinases (tCDKs) that trigger release of Pol II from promoter-proximal pausing and facilitate productive Pol II elongation along genes. We aim to exploit the knowledge on basic principles of gene regulation to help devise novel treatments of many diseases that stem from misregulated gene transcription programs. More information about the lab, including the latest research and news, can be found here: https://www.helsinki.fi/en/researchgroups/center-for-gene-regulation
We are looking for a creative thinker with strong analytical skills and a passion for science. We expect you to formulate your own hypotheses, propose experimental design to address them, and take advantage of the laboratory/research community’s intellectual and skill resources to advance the knowledge of the field. The competitive candidate should hold a PhD degree in molecular biology, biochemistry, biotechnology or related fields. Expertise in biochemistry and molecular biology is a pre-requisite for the position. In addition, we appreciate fluency in the analysis of NGS data. Strong command in written and spoken English is required.
The successful candidate will receive training in a comprehensive set of biochemical, molecular biology and cell line-based functional assays, as well as cutting-edge systems biology methods, such as CRISPRi and nascent transcriptomics methods. The training will be furthered by research visits as part of our collaborations with a network of well-regarded laboratories around the globe. Current projects in the lab funded by the 4-year Research Council of Finland grant, 3-year Sigrid Juselius Foundation grant and Cancer Foundation Finland grant, Sigrid Juselius Foundation revolve around fundamental biology of tCDKs and their combinatorial targeting in cancer.
The salary of the selected candidate will be based on the University’s salary scheme for teaching and research personnel composed of task specific and personal performance components. A trial period of six months will be applied.
The University of Helsinki offers comprehensive services to its employees, including occupational health care and health insurance, unemployment and pension fund, a generous holiday package, sports facilities, and opportunities for professional development: https://www.helsinki.fi/en/about-us/careers.
The appointee is expected to reside in Finland while employed by the University of Helsinki. International staff is supported in relocating to Finland: https://www.helsinki.fi/en/about-us/careers/welcome.
Please submit your application, together with a motivation letter including a summary of your research interests, CV, list of publications and two letters of reference, through the University of Helsinki electronic recruitment system by clicking on the ’Apply now’ button.
Internal applicants (i.e., current employees of the University of Helsinki) submit their applications by using the Employee Login button.
The University of Helsinki welcomes applicants of any gender, linguistic and cultural background or minority group.
The closing date for application is September 9th, 2024. The shortlisted candidates will be notified about the interview shortly afterwards.
For further information, please contact Matjaž Barborič, Ph.D.; matjaz.barboric(at)helsinki.fi
Recent publications:
Wang Z et al. (2023) Inhibition of CDK12 elevates cancer cell dependence on P-TEFb by stimulation of RNA polymerase II pause release. Nucleic Acids Res 51(20):10970-10991
Wang Z et al. (2023) P-TEFb promotes cell survival upon p53 activation by suppressing intrinsic apoptosis pathway. Nucleic Acids Res 51(4):1687-1706
Bugai A et al. (2019) P-TEFb activation by RBM7 shapes a pro-survival transcriptional response to genotoxic stress. Molecular Cell 74(2): 254-267