Faculty of Medicine, Biomedicine and Internal Medicine
The University of Oulu is one of the biggest and most multidisciplinary universities in Finland. We create new knowledge and innovations that help to solve global challenges. We offer you an international and inspiring working environment where you are given responsibility and can use your skills, develop yourself and do work that matters. Our flexible and family-friendly workplace makes it easy for you to balance work and leisure. The University of Oulu is ranked in the top 3% of the world´s universities.
We are now looking for
Two Doctoral Researchers
to join us at the Research Unit of Biomedicine and Internal Medicine at the Faculty of Medicine.
About the job
We are looking for two doctoralresearchers to join the research group of Associate Professor Eija Pirinen or Professor Karl-Heinz Herzigat the Biomedicine and Internal Medicine Research Unit, the Faculty of Medicine in a project aiming at the regulation of metabolic control for the treatment of obesity and metabolic diseases.
Description of the project: Mitochondrial dysfunction has emerged as a prominent feature in metabolically important peripheral tissues in obesity and metabolic diseases. Consequently, mitochondrial targeting is nowadays considered as a promising treatment approach for these diseases. In this project, we will elucidate novel treatment strategies to improve metabolic control. This research project is funded by the Biocenter Oulu as one of the spearhead projects related Lifelong Health focus area.
What you will do?
You will use in vitro and in vivo models to study the effect of novel treatment strategies on cellular, whole organ (spheroids) and animal metabolism. You will need to analyse the outcome using various biochemical assay systems. Animal licence and previous experience in the field of obesity and metabolic diseases is of advantage.
What we offer?
We offer a research environment with excellent technological facilities and a motivating and supporting international community at the Faculty of Medicine, University of Oulu.
We also offer access to state-of-the-art methods and facilities located at Oulu, Finland, for doing cutting-edge research in the field of obesity and metabolic diseases.
We offer you a place in a highly talented research group, working to solve globally significant research problem.
We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.
Who are you?
We seek highly motivated scientists who have the ability to work independently as well as in a group with a drive to excel in research.
In order to succeed and enjoy the position, we expect from you:
Master’s degreein the field of life sciences such as molecular biology, biochemistry, biotechnology, pharmacy or related fields.
The following experience and skills would be helpful:
Prior experience in measuring mitochondrial function (mitochondrial respirometry analyses).
The knowledge of 3D cell culture models.
The skills and competences listed below will also be valued:
Finnish communication skills
Collaboration/Team work
Goal-oriented
Good IT and teaching skills
Multitasking skills
Salary
The position isfixed-term for4 years as of 01.01.2024 or as soon as possible thereafter.
The salary will be based on the levels 2-4 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 2300-2600 € per month (before taxes). A trial period of 6months is applied in the position.
How to apply?
Interested? If yes, please apply by 08.11.2023 (23:59 Finnish local time) through our recruitment system.
The application should be written in English and include the following:
Contact information of two persons available for recommendation
The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview. All applicants will be notified during the selection process.
We welcome applicants from all backgrounds, such as people of different ages, genders and lingual, cultural or minority groups.
Contact Information
If you have any further questions, please contact Associate Professor Eija Pirinen eija.pirinen@oulu.fi or Professor Karl-Heinz Herzig karl-heinz.herzig@oulu.fi.
Oletko vastavalmistunut ja etsit ensimmäistä työpaikkaasi asiantuntijana? Ehkä haluat vaihtaa alaa ja päästä nopeasti kiinni uuden urasi alkuun? Kasven Health & Tech Top Expert-RekryKoulutuksen myötä pääset aloittamaan asiantuntijaurasi suoraan korkean teknologian huippuyrityksessä!
Tezted etsii Health & Tech Top Expert-RekryKoulutuksen kautta In Vitro Diagnostiikan-myyntiosaajaa. Jyväskyläläinen Tezted tarjoaa alan johtavia ratkaisuja monimutkaisten sairauksien havaitsemiseen. IVD-myyntiosaajana edustat ja myyt laajan In Vitro -diagnostiikkavalikoimamme tuotteita terveydenhuollon organisaatioille, kliinisille laboratorioille, tutkimuslaitoksille sekä muille potentiaalisille asiakkaille. Työssäsi pyrit saavuttamaan myyntitavoitteet sekä kasvattamaan markkinaosuuttamme. Rooliin kuuluu myynnin ja liiketoiminnan kehittämiseen liittyviä tehtäviä (esim. myyntisuunnitelmien kehittäminen ja toteuttaminen, myyntiesittelyiden ja neuvotteluiden pitäminen), asiakashallintaa (esim. asiakassuhteiden rakentaminen ja ylläpito, konferensseille ja messuille osallistuminen) sekä markkinatutkimusta (esim. markkinadatan kerääminen ja analysointi).
Toivomme, että sinulla on korkeakoulututkinto (kandidaatti tai maisteri) soveltuvalta alalta, (esim. biologia, biokemia tai lääketieteet) sekä kokemusta myyntityöstä. Tietämys IVD-tuotteista, teknologioista sekä toimialan regulaatioista on etu. Arvostamme vahvoja vuorovaikutustaitoja sekä erinomaisia neuvottelu- ja ihmissuhdetaitoja. Menestyäksesi tässä roolissa tarvitset aitoa kiinnostusta myyntityöhön ja asiakaspalveluun. Myös oma-aloitteinen ja start-up-henkinen asenne on etu. Työkielemme on englanti, muu kielitaito luetaan vahvuudeksi.
Tarjoamme sinulle merkittävän roolin ammattitaitoisessa tiimissämme: sinulla on mahdollisuus kasvattaa IVD-tuotteidemme myyntiä ja luoda vahvoja suhteita keskeisiin asiakkaisiimme. Työskentelemme Jyväskylän toimistollamme. Hae pian ja kerro lisää itsestäsi!
Työpaikan hakeminen ja hakuehdot RekryKoulutukseen
Työpaikkaa haetaan Health & Tech Top Expert-RekryKoulutuksen kautta.
Hakijan tulee olla työtön työnhakija, työttömyysuhan alainen tai osa-aikaisesti työskentelevä. Hakijoilta edellytetään soveltuvaa korkeakoulututkinto (AMK tai yliopisto) tai riittävästi soveltuvaa työkokemusta esimerkiksi seuraavilta aloilta:
Health & Tech Top Expert-RekryKoulutus toteutetaan yhteistyössä paikallisten TE-palveluiden ja ELY-keskusten kanssa. Hakuprosessi ja opiskelijoiden rekrytointi tehdään yhteistyössä Pirkanmaan ja Keski-Suomen TE-palveluiden kansa. RekryKoulutus on osallistujalle maksuton.
Antibody-Drug Conjugates Research Team is seeking a highly motivated, skilful, and independent Senior Scientist with experience in preclinical cancer research. You should have a track record of scientific excellence in modern cell- and molecular biology-based methodologies. As Senior Scientist you will work collaboratively with a multidisciplinary team of scientists and researchers to advance the discovery of novel cancer targets and participate in the development of the first/best-in-class Antibody-Drug Conjugates (ADCs) from concept to clinical candidate phase. This position offers an exciting opportunity to apply the candidate’s expertise in cancer research and contribute to the development of potentially lifesaving therapies.
Key Responsibilities
The candidate for this position will:
Develop and execute strategies for target identification and evaluation.
Perform target validation studies such as analysis of target expression, quantification, distribution, internalization, and intracellular trafficking.
Conduct and/or coordinate in vitro experiments to assess the critical properties of ADCs and their components.
Establish and implement novel assays to characterize ADCs.
Provide cancer biology expertise and guidance for the project team/organization.
Collaborate with cross-functional teams, including medicinal chemists, pharmacologists, biologists, and clinical researchers to answer scientific questions and drive projects forward.
Take charge of collaborations and externally partnered research.
Perform data analysis of experimental results and regularly report work progress in the project team and organization meetings.
This permanent position is based in Turku, Finland, and you will report to the Head of the Antibody-Drug Conjugates Team.
Description Of Unit
Antibody-Drug Conjugates Team is one of three scientific units in Oncology Research, a part of Orion’s R&D Organization. Antibody-Drug Conjugates Team is focused on the discovery of therapeutic targets and active development of ADCs utilizing a broad panel of biophysical, biochemical, cellular, and in vivo methods. Our aim is to develop cutting-edge ADC therapies that can transform cancer patients’ lives.
We Offer
At Orion we offer you, among others:
Opportunity to work with a dynamic and experienced team of in vitro and in vivo scientists and assistants building up Oncology Research at Orion.
An exciting R&D pipeline and enthusiastic working environment with opportunities to use your strengths to build your competence and career.
Exciting opportunity to innovate and have an impact on future therapies for patients.
We have an excellent working atmosphere based on the appreciation of colleagues, continuous development, and mutual trust. Read more about our values.
In addition, Orion supports integration of international talents into Finland with the help of a relocation programme. Read more on our webpages.
Essential Requirements
To be successful in this role, the candidate must have the demonstrated knowledge, skills, and abilities in the following:
Ph.D. or master’s degree with 8+ years of academic or industry experience in a relevant discipline (Biological Sciences, Biochemistry or equivalent).
Understanding of cell and molecular biology and/or biochemistry in the context of cancer biology.
Knowledge and hands-on experience in cell- and molecular biology-based methodologies, including multichannel/multicolour flow cytometry, fluorescent and live cell microscopy, cytotoxicity assays, fluorescent labelling, qPCR, western blotting, and ELISA.
Experience with routine 2D cell culture models.
Demonstrated ability to work independently and collaborate effectively as a member of a multidisciplinary research team, and mentor junior team members.
Strong desire to continue seeking new technological innovations supporting laboratory work.
Excellent problem-solving and critical-thinking skills.
Strong communication and presentation skills.
Desirable Requirements
Experience in the design and development of biologics and/or conjugates.
Knowledge of bioinformatics and omics-type data analysis.
Prior experience in the biopharmaceutical industry.
Additional Information
Applications will be accepted until the 15th of October 2023. We will start reviewing applications during the application period.
For additional details, don’t hesitate to get in touch with Dr Marcin Chrusciel, Head of Antibody Drug Conjugates Team tel. +358 509667861 on the following times (Finnish Time): 6th of October 15:00-16:00 or 12th of October 15:00-16:00.
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person. Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.
Turun yliopiston lääketieteellisen tiedekunnan biolääketieteen laitokseen kuuluva syöpätutkimusryhmä Medical Immune Oncology Research Group (MIORG, https://www.miorg.fi/) hakee innostunutta ja kokenutta tutkijatohtoria työskentelemään syövän immunoterapian kehittämiseen liittyvässä projektissa. Projektia johtaa Akatemiatutkija, dosentti Carlos Rogerio de Figueiredo. Tutkimusryhmän työkieli on pääasiassa englanti.
Käyttämällä käänteistä translaatiomallia tutkimusryhmässä hyödynnetään edistyneintä teknologiaa metastaattisen syöpänäytteiden profiloimisessa ja bioanalyysien tekemisessä sekä eläin- että humaanikudoksista keskittyen ensisijaisesti löytämään soveltuva biomarkkeri hoitojen kehittämisen järkeväksi suuntaamiseksi.
Tehtävään valittava tutkijatohtori johtaa tutkimusta, jossa keskitytään erityisesti innovatiivisten virtaussytometritekniikoiden käyttöön, mukaan lukien in vitro – ja in vivo -toimintatutkimuksiin pohjautuvat immunomekanistiset tutkimukset single-cell multi-color full spectral virtaussytometrillä. Tehtäviin kuuluu sytometrillä tehtävien kokeiden suunnittelu, toteuttaminen ja tarkkojen data-analyysien laatiminen. Tutkijatohtori tekee tutkimusta myös yhteistyössä ryhmän jatko-opiskelijoiden kanssa, ja häntä kannustetaan kehittämään muita alaan liittyviä tutkimushankkeita (mukaan lukien syövän immunogeeniset tutkimukset).
Tehtävä on kaksivuotinen ja alkaa tammikuussa 2024. On mahdollista, että tehtävä jatkuu tämän jälkeen (yhteensä 4 vuotta). Valitun henkilön toivotaan aloittavan tammikuussa, mutta aloituksesta voidaan neuvotella.
Edellytykset
Tohtorin tutkinto soveltuvalta tieteenalalta (solubiologia, molekyylibiologia, biokemia, tai vastaava)
Voimassa oleva eläintyölupa Suomessa tai Iso-Britanniassa/EU-alueella, pätevyys kudosviljelytekniikoissa sekä yksisoluvärjäyksissä, erityisesti virtaussytometriä varten
Syvällinen asiantuntemus virtaussytometriaan ja single-cell -kudosten käsittelyyn liittyen, perehtyneisyys FlowJO:n kaltaisiin työkaluihin sekä bioinformatiikan ja tilastotieteen perustyökaluihin
Kokemus humaani-/eläinnäytteiden käsittelystä ja terapeuttisesta/lääketutkimuksesta
Taidot reagenssien ja mekanististen tutkimusten toiminnallisten kontrollien suunnitteluun ja valmistukseen sekä vahva ote menetelmien ja varaston hallintaan.
Sujuva suullinen ja kirjallinen englannin kielen taito sekä vankka organisointikyky.
Eduksi katsotaan
Kudosten immunofluoresenssi- ja mikroskooppitekniikoiden tuntemus.
Immunohistokemian tekniikoiden osaaminen.
Kokemus/hankittu koulutus CyTOF-näytteiden valmistelusta ja tietojen analysoinnista.
Kokemus NanoStringin (nCounter, Geo MX tai CosMX) käytöstä.
Aikaisempi kokemus R/Python-ohjelmoinnista.
Tehtäväkohtainen palkkaus määräytyy yliopistojen palkkausjärjestelmän mukaisesti ja on opetus- ja tutkimushenkilöstön vaativuustasoilla 5-6. Palkkaus on aiemmasta kokemuksesta ja osaamisesta riippuen tyypillisesti noin 3686-4041 e/kk työsuhteen alkaessa. Tehtävässä on 6 kuukauden koeaika.
Tarjoamme sinulle vastuullisia ja mielenkiintoisia työtehtäviä sekä mahdollisuuden kehittää osaamistasi monipuolisessa toimintaympäristössä. Huolehdimme työhyvinvoinnistasi ja arkesi toimivuudesta mm. joustavien työaikojen sekä hyvinvointipalvelujemme avulla. Lue lisää Turun yliopistosta työnantajana: Tervetuloa meille töihin
Hakemus tulee jättää viimeistään 22.10.2023 (klo 23.59) yliopiston sähköisellä hakulomakkeella. Linkki järjestelmään on ilmoituksen alussa (”Täytä hakemus”). Ilmoitus on luettavissa osoitteessa http://www.utu.fi/tyopaikat. Hakemus tulee täyttää englanniksi.
Hakemukseen tulee liittää
motivaatiokirje
ansioluettelo (enintään 3 sivua)
julkaisuluettelo (ml. lyhyt/kolmerivinen kuvaus osuudestasi kymmeneen tärkeimpään julkaisuun).
vähintään kahden suosittelijan yhteystiedot.
Lisätietoa tehtävästä antaa (englanniksi) tutkimusryhmän johtaja, dosentti Rogerio De Figueiredo, crdefi@utu.fi
Hakua koskeviin teknisiin kysymyksiin vastaa henkilöstöasiantuntija Kristiina Nuutila, kristiina.nuutila@utu.fi, puh. +358 50 313 5224
Arvostamme yhdenvertaisuutta ja monimuotoisuutta työyhteisössämme ja kannustammekin päteviä hakijoita taustasta riippumatta hakemaan avoimia tehtäviämme.
Turun yliopisto on maailmanluokan monialainen tutkimusyliopisto, joka tarjoaa haasteellisia työtehtäviä ja ainutlaatuisen näköalapaikan suomalaiseen ja kansainväliseen tiede- ja koulutusmaailmaan. Turun yliopisto laajentaa tutkimustaan materiaali- ja konetekniikkaan, ja vuoden 2021 alusta aloitti uusi Teknillinen tiedekunta ja sen myötä Kone- ja Materiaalitekniikan laitos. Haemme nyt
yhtä määräaikaista tutkijatohtoria biolääketieteellisille rajapinnoille apulaisprofessori Emilia Peltolan johtamaan Terveysteknologian materiaalit -ryhmään.
Tehtävän aloitusaika on mahdollisimman pian, ja tutkijatohtorin työsuhde jatkuu 31.8.2026 saakka.
Jos olet kiinnostunut tutkimaan biolääketieteellisiä rajapintoja, kuulut tiimimme! Tässä tehtävässä sinulla on ainutlaatuinen mahdollisuus hyödyntää materiaalikemian ja -fysiikan ja rajapintailmiöiden ymmärrystä terveysteknologian antureiden kehittämiseksi. Anturiteknologia on tärkeä tekijä edistämään terveydenhuollon fokuksen siirtymistä sairaudenhoidosta ennaltaehkäisevään terveydenhoitoon. Tutkimusryhmämme keskittyy hermovälittäjäaineita, hormoneita ja malariaa mittaavien nanomateriaaleihin perustuvien sähkökemiallisten antureiden kehittämiseen. Pyrimme kontrolloimaan sähkökemiallista vastetta, anturin likaantumista ja elimistön vastetta suoraa elektrodin materiaalilla. Etsimme henkilöä, joka on aloitteellinen ja jolla on kokemusta apta-antureista ja/tai sähkökemiasta.
Vaatimukset
Tehtävässä edellytetään hyvät tiedot aptameereista ja/tai sähkökemiasta. Etsimme tutkijaa, joka parhaiten sopii meneillään oleviin projekteihin: Biohybridihiilimateriaalit naissukupuolelle tyypillisten hormonien mittauksessa. Tehtävässä menestyminen edellyttää sujuvaa suullista ja kirjallista englannin kielen taitoa.
Tutkijatohtorilla on oltava tohtorin tutkinto soveltuvalta alalta (esim. materiaalitekniikka, kemia, fysiikka, bioteknologia). Tohtorintutkinto tulee olla suoritettuna hakuajan päättymiseen mennessä.
Materiaalitekniikan yksikkö tarjoaa nuoren ja dynaamisen työyhteisön. Kannustamme tiimiämme saavuttamaan parhaansa ja kehittämään osaamistaan monipuolisessa toimintaympäristössä. Kannustamme sinua erinomaisuuteen ja olemme sitoutuneet tukemaan sinun työhyvinvointia ja jokapäiväisen elämän toimivuutta tarjoamalla esimerkiksi joustavat työajat ja hyvinvointipalvelut.
Tehtäväkohtainen palkkaus määräytyy yliopistojen palkkausjärjestelmän opetus- ja tutkimushenkilöstön mukaisesti. Tutkijatohtorin palkkaus aiemmasta kokemuksesta ja osaamisesta riippuen on tehtävän alussa noin 3340-3530 euroa/kk.
Tutkijatohtorin tehtävissä on kuuden (6) kuukauden koeaika.
Hakemukset tulee jättää viimeistään sunnuntaina 22.10.2023 (klo 23:59) yliopiston sähköisellä hakulomakkeella. Linkki järjestelmään on ilmoituksen alussa kohdassa (”Täytä hakemus”). Ilmoitus on luettavissa osoitteessa: http://www.utu.fi/tyopaikat.
Hakemukseen on liitettävä CV, tutkintotodistukset sisältäen opintorekisteriotteen, julkaisuluettelo ja motivaatiokirje. Lisää motivaatiokirjeeseen kahden suosittelijan nimet ja yhteystiedot. Hakemuksessasi voit kertoa tarkemmin opinnoistasi, tulevaisuuden opintosuunnitelmista sekä soveltuvuudesta tutkimushankkeeseen.
The University of Oulu is one of the biggest and most multidisciplinary universities in Finland. We create new knowledge and innovations that help to solve global challenges. We offer you an international and inspiring working environment where you are given responsibility and can use your skills, develop yourself and do work that matters. Our flexible and family-friendly workplace makes it easy for you to balance work and leisure. The University of Oulu is ranked in the top 3% of the world´s universities.
We are looking for applications for full-time
POST-DOCTORAL RESEARCHER
position, starting at 1.1.2024 in University of Oulu, Finland. Successful applicants will belong to the strategic Biocenter Oulu spearhead project headed by the professors Lauri Eklund and Vesa Kiviniemi providing highly complementary expertise in endothelial cell and molecular biology, advanced microscopic imaging, disease modeling, clinical neuroimaging, and brain clearance therapy research.
SUBJECT FIELD: Brain is metabolically highly active organ and requires an efficient system to remove the resulting waste, while failures in the clearance can cause Alzheimer’s disease (AD). The mechanisms which regulate waste clearance are incompletely understood.
DESCRIPTION OF POSITION: Work will be carried out in the research group headed by Professor Lauri Eklund (at the Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu) focusing on vascular biology and metabolic waste clearance mechanisms in the central nervous system. In this project we investigate roles of the extracellular matrix (ECM) in the brain clearance and pre-clinically test potential treatments to enhance brain clearance functionality. Research technologies mainly used are biochemical and cell biological methods, advanced microscopy, and genetic mouse models.
REQUIREMENTS: To successfully occupy the position, the candidate must possess a doctoral degree in the field of medical biochemistry, molecular/cell biology, or medicine and have expertise in the ECM and vascular biology. Prior experience in generation and analysis of gene-modified mice (knockout/knockin and cell-type specific inducible models); in biochemical, histological and advanced microscopic imaging methods; and knowledge in transcriptomic analysis are required. The ability to pursue independent research, supervise younger scientists, teaching experience and fluency in written and spoken English are expected. Priority is given to the applicant who can start on January 1st, 2024.
WHAT WE OFFER:
You will become a part of a highly talented, multidisciplinary research team working on strategically and globally significant research area.
Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits here.
Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu.
Development and career options of the big organization.
We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.
WHO ARE YOU?: In your cover letter, please describe the qualifications relevant for the job as bullet points. Add also other merits applicable to the job. Clearly separate requirements that are expected and those that are seen as an advance.
SALARY: The position is fixed-term for 4 years as of 1.1.2024 or as soon as possible thereafter. The salary will be based on the levels 5-6 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 3600-4200 € per month (before taxes). A trial period of 6 months is applied in the position.
HOW TO APPLY?: Please apply by 8.11.2023 (23:59 Finnish local time) through our recruitment system. The application should be written in English and include the following:
Cover letter
CV following the guidelines of the Finnish Advisory Board on Research Integrity
List of publications following the guidelines of the Academy of Finland
Certificates/Diplomas
Contact information of two persons available for recommendation
The eligible applicants fitting best in the profile expected for the position can be invited to an on-site or remote interview. All applicants will be notified during the selection process.
We welcome applicants from all backgrounds, such as people of different ages, genders and lingual, cultural or minority groups.
CONTACT INFORMATION: If you have any further questions, please contact Professor Lauri Eklund, lauri.eklund@oulu.fi
Are you interested in plant biotechnology and plant-derived high-value compounds and looking for a new postdoctoral opportunity in the field? Would you like to do impactful research in the cutting edge of natural sciences with superb colleagues who are top expert in their field? VTT might be just the place for you. If you are an international talent searching for a new opportunity, read more about the benefits of living in Finland and VTT’s support for relocation here !
VTT is one of the leading applied research organisations in Europe. What unites us are curiosity, a passion for learning and a purpose: to solve the biggest challenges of our time and turn them into sustainable growth and well-being. Our cross-disciplinary community of over 2000 brilliant minds is focused on creating impact through science-based innovation. Get to know us further by exploring VTT’s tech & infra.
We are now looking for a Post-doctoral Scientist to join our Plant Biotechnology team. As a research scientist, your key goal is to engineer metabolic pathways towards capsinoids and capsaicinoids both in plants and yeast using novel engineering tools. In this position, you will be the responsible researcher in an Academy of Finland -funded project. You get to develop a biotechnological production system for the selected high-value plant metabolites using state-of-the-art techniques.Our team, Plant Biotechnology, works on developing plants, plant cells, microalgae, and other plant-based raw materials for the sustainable production of biomass, ingredients, high-value chemicals, and proteins. Product development can be facilitated by metabolic engineering including synthetic biology. Our approaches enables a stable supply in combination with safe and contained production processes. This results in economical and clean products. We offer plant cell and tissue culture technology from initiation up to industrial scale.This position supports long term career opportunities in applied research, industry or academia. The focus is in advancing specified research targets and active publication of research results. VTT started a Postdoc programme in 2023 to develop new ways to support scientific excellence and to strengthen career paths from universities to VTT. VTT wants to provide development opportunities for recent university PhDs in applied research and industry collaboration. As a Postdoctoral Researcher at VTT, you are able to make an impact for our customers and society. Our researchers work closely together with industry, often in interdisciplinary research groups. VTT has excellent and internal services to support your research work.The position is located in Espoo and it is a 2 year temporary contract.
Your responsibilities as a Post Doctoral Researcher:
Study biosynthetic pathway engineering in plants and yeast in a defined project
Conduct laboratory work including cell culturing, molecular biology work and chemical analyses
Plan experiments, analyse the data and communicate project results
Report the results regularly to the project team and prepare scientific publications
Who we are looking for:
You have a doctoral degree related to plant science
Track record in metabolic engineering of plants
Experience in genome editing techniques
Experience with yeast transformation is a plus
As a person, we hope that you are:
An open-minded and innovative person with a vision on longer term research needs. You have a strong passion for work. You are eager to work with new topics and methods, even out of your comfort zone to achieve the set ambitious goals. We appreciate the ability to tolerate pressure and maintain good work-life balance, as well as the willingness to collaborate with experts and partners across different fields.
With VTT, you’ll enjoy:
Natural sciences with an impact. VTT works on the cutting-edge of natural sciences, and we’ve invested into building state-of-the-art research facilities for natural sciences, such as the Bioruukki pilot infrastructure for bio- and circular economy. Our research agenda is dedicated to solving systemic and technological challenges, such as reaching carbon neutrality and unleashing the power of synthetic biology. That means that at VTT, your expertise in natural sciences will go towards creating real impact. Read more about our strategy – the path of exponential hope .
Superb colleagues and community. With VTT, you’ll join a community of over 2000 multidisciplinary experts who foster a culture of trust, openness and sharing knowledge. We work truly across disciplines, and house all the cutting-edge sciences from quantum computing to synthetic biology under one roof. Collaborating with superb colleagues is a source of learning, inspiration, and fun. Read more about our organisational culture as the builder of the world’s most meaningful place to work.
Nordic work–life balance. Working in Finland, the world’s happiest country enables an excellent quality of life. At VTT, we make our people’s well-being a strategic priority. We offer six weeks of paid vacation a year. Our benefits include comprehensive occupational healthcare and a range of well-being services, such as exercise, culture benefits, and hobby clubs. If you are an international talent searching for a new opportunity, read more about the benefits of living in Finland and VTT’s support for relocation here .
A great career in research. We offer long-term positions and flexible career paths in top-level research. People tend to stay with us for over ten years, as you can advance to different roles and responsibilities within VTT. At VTT, researchers have the flexibility and independence to affect the content of their work. Combining cutting-edge academic research and applied customer projects keeps your career path interesting.
Apply now and join our community of brilliant minds! Please send your CV and answers to 3 position specific questions with your salary request via our recruitment system as soon as possible but at the latest by 22nd of October 2023. We will process applications as they come in, and fill in the position as soon as we find the right candidate. A security clearance procedure may be conducted during the recruitment process.
Interested and want to hear more?
For further information, please contact Research Team Leader Heiko Rischer heiko.rischer@vtt.fi
VTT
VTT is a visionary research, development and innovation partner. We drive sustainable growth and tackle the biggest global challenges of our time and turn them into growth opportunities. We go beyond the obvious to help the society and companies to grow through technological innovations. We have 80 years of experience of top-level research and science-based results. VTT is at the sweet spot where innovation and business come together.
Tampere University and Tampere University of Applied Sciences create a unique environment for multidisciplinary, inspirational and high-impact research and education. Our university community has its competitive edges in technology, health and society. www.tuni.fi/en .The BioMediTech Unit of the Faculty of Medicine and Health Technology jointly with StemSight Oy is looking for a Postdoctoral Research Fellow specializing in cell and molecular biology.
The position will be filled for a fixed-term period of two years and is funded by the Finnish Research Impact Foundation. Half of the work will be carried out at StemSight Oy although employment contract will be made with Tampere University.The Faculty of Medicine and Health Technology (MET) is committed to high quality research and education in the fields of biomedical engineering, biotechnology, medicine, and health technology. We conduct basic, applied, clinical, and translational research in collaboration with Tampere University Hospital (TAYS). Our existing research areas in health research include biomedical engineering fields from biomaterials and microtechnologies to health data science, cell and molecular biology, with applications in areas such as cancer, cardiovascular and celiac diseases, immunology, and ophthalmology.
Professor Heli Skottman’s eye regeneration group develops novel human stem cell-based tools for corneal and retinal repair through cell transplantation and ophthalmic in vitro tissue models that can be used to model human-specific eye disorders. For additional details see our web page: https://research.tuni.fi/eye-group/StemSight Oy is a spinout company from Tampere University, commercializing iPSC-based therapies for the treatment of corneal blindness. More information at https://www.stemsight.fi/
Job Description
We are seeking a talented and motivated postdoctoral researcher to independently work with human induced pluripotent stem cells and their differentiation towards corneal endothelial cells. The candidate will be responsible for improving and optimizing a previously developed differentiation process to ensure research translation towards clinical and commercial use. The primary emphasis will be on developmental biology, advanced cultivation of human pluripotent stem cells, and their guided differentiation through the manipulation of signaling pathways. The research necessitates a profound understanding and passion for molecular signaling regulation within cells and employing a diverse array of molecular techniques, which encompasses advanced flow cytometry and imaging methodologies. In addition, there will be a need for data analysis, the creation of publications and reports. Importantly, the job includes active working and communication in the interface of academic research and industrial R&D and collaboration with academic and industrial R&D colleagues and support staff, both internally and within external networks.
Requirements
An applicable doctoral degree in the field of medicine, cell biology or molecular biology.
Versatile and independent researcher expertise in cell biology.
A solid background in cell and molecular biology as well as culturing of human cells.
Candidates with additional research experience with human pluripotent stem cells will be highly valued.
Technical skills in flow cytometry, qPCR and immunofluorescence.
While experience within the international eye research community is valued, it is not a mandatory requirement.
Excellent communication skills and fluency in English (both written and oral) will be considered important for the position.
The position also requires that the candidate is able to meet the responsibilities identified in laboratory and ethical guidelines.
Please describe your relevant experience and skills in detail in the cover letter, and please be prepared to provide proof of your merits when requested.
Tampere University is a unique, multidisciplinary, and boldly forward-looking community. Our values are openness, diversity, responsibility, courage, critical thinking, and learner-centeredness. We hope that you can embrace these values and promote them in your work.
Weoffer
The position is a fixed-term contract for two years, starting on 1 January, 2024. A six-month trial period applies to all new employees.
Salaries are based on job demands and employees’ personal performance in accordance with the salary system of Finnish universities . The position of a Postdoctoral Researcher is placed on the job demands levels 5-6 (teaching and research staff). A typical salary of Postdoctoral Researcher in this demand level is around 3500-4000 EUR/month.
As a member of the dynamic and innovative international community of Tampere University, you will have access to a range of competitive benefits, including occupational health care services, flexible work schedules, versatile research infrastructure, modern teaching facilities, and a safe and inviting campus area. You will also have a personal fund to spend on sports and cultural activities during your free time. Please read more about working at Tampere University . You can also find more information about us and working and living Tampere by watching our video: Tampere Higher Education Community – our academic playground .Tampere is the largest inland city in Finland and is considered a major academic hub in the Nordic countries. The region is home to a vibrant, knowledge-intensive entrepreneurial community, and the city is an industrial powerhouse with a rich cultural scene and a reputation as a centre of Finland’s information society. Additionally, Finland is known for being one of the most stable, free, and safe countries in the world, based on various ratings by prominent agencies. Tampere is surrounded by stunning nature, with forests and lakes offering countless opportunities for easy-to-access outdoor adventures and refreshment throughout the year.
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HowtoapplyPlease submit your application through our online recruitment system (link provided below). The closing date for applications is October 31st, 2023 (at 23.59 EEST, UTC+2). All application materials, including the accompanying documentation, should be written in English and attached in PDF format.
Please Ensure That Your Application Includes The Following Documents
Curriculum Vitae
List of publications
References from two individuals
Cover letter, which should include a brief introduction of the applicant, previous research experience, and motivation to apply this position with future perspectives.
Please note that incomplete applications will not be considered. If you have any questions regarding the application process or the position, please do not hesitate to contact us using the contact details provided in the job advertisement.We look forward to receiving your application and thank you for your interest in joining our dynamic and innovative community at Tampere University.
For Further Information, Please Contact
Professor Heli Skottman, tel. +358 50 396 9645, heli.skottman@tuni.fiFor questions regarding the application process, please contact HR Specialist Lilli Sarasvirta, lilli.sarasvirta@tuni.fiTampereen yliopisto ja Tampereen ammattikorkeakoulu muodostavat yhdessä Suomen toiseksi suurimman monitieteisen, innostavan ja vaikuttavan tutkimus- ja oppimisyhteisön. Korkeakouluyhteisömme osaamiskärjet ovat tekniikka, terveys ja yhteiskunta. Lue lisää: www.tuni.fiTampereen yliopiston lääketieteen ja terveysteknologian tiedekunnan BioMediTech-yksikössä on haettavana tutkijatohtorin määräaikainen tehtävä solu- ja molekyylibiologian alalta.Lääketieteen ja terveysteknologian tiedekuntamme on monialainen biolääketieteen tekniikan, bioteknologian, lääketieteen ja terveysteknologian tutkimuksen ja opetuksen korkeatasoinen yksikkö. Teemme kansainvälisesti merkittävää perus- ja soveltavaa tutkimusta.Lue tarkemmat tiedot tehtävästä ja hakuohjeet yllä olevasta englanninkielisestä ilmoituksesta. Jätäthän hakemuksesi yliopiston sähköisellä hakulomakkeella (linkki löytyy tämän ilmoituksen alta).
Research Program Unit at the Faculty of Medicine at the University of Helsinki invites applications for a fixed-term position of
Postdoctoral Researcher
from 1 November 2023 until 31 October 2024 with a possibility of extension.
The position is available in an Academy of Finland -funded project that investigates the interplay of metabolic reprogramming, epigenetic regulatory landscape, and cancer cell proliferation.
The group is working in the field of cancer biology and epigenetics using state-of-the-art methods such as CRISPR-Cas9 genome editing and transcriptional and epigenomic profiling at single-cell resolution (see e.g., Pihlajamaa et al, Nat Biotech 2023). We utilize diverse cellular models and next-generation sequencing techniques to understand the molecular mechanisms controlling oncogenic gene expression programs and cancer growth. The group belongs to the Applied Tumor Genomics Program in the Research Programs Unit of the Faculty of Medicine at the University of Helsinki providing a vibrant research environment and high-quality infrastructure for modern biomedical research.
Qualifications
A PhD degree in life sciences with excellent academic record. The default assumption is that the degree requirement must be met by the beginning of the employment.
Working knowledge of biochemistry, molecular biology, and mammalian cell culture
Ability to work productively both independently and as part of the team
Excellent communication skills in English
The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.
In addition, previous experience in CRISPR/Cas9-mediated genome editing and next-generation sequencing-based functional genomics methods and/or computational analysis of genomic datasets is considered a plus, and candidates with proven track record with at least one first-author publication will be given preference.
What We Offer
Salary of 3300-3600 euros per month depending on the appointee’s qualifications and experience.
An exciting project utilizing cutting-edge functional genomics and CRISPR-methods to understand molecular basis of human cancer.
A position in an ambitious research group with supportive and positive working culture in an international and multi-disciplinary research environment.
Attractive welfare benefits such as occupational health care provided by University of Helsinki (further information at www.helsinki.fi/en/about-us/careers).
How To Apply
Applications should be submitted through the University of Helsinki Recruitment System via the ”Apply now” button. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi. The closing date for applications is 26 October 2023. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .
For further information on the position, please contact Dr. Päivi Pihlajamaa paivi.pihlajamaa(at) helsinki.fi).
For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk(at) helsinki.fi).
About Us
The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.
The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.
Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.
We are looking for a Research Assistant to join our Immuno-Oncology team. You will be based in Turku, Finland and report to Head of Immuno-Oncology. This is a 2 year fixed-term position.
Your main responsibilities will include:
Culture of both primary and established mammalian cell lines
Support Oncology scientist with in vitro and ex vivo cell based assays
Process human blood samples by adhering to Standard Operating Procedures
Analysis of samples employing specific techniques such as flow cytometry, cell sorting, PCR, western blotting and incucyte assays
Assist in establishing and improving all procedures and required SOP documentation
Maintain high standards of housekeeping and participate in routine laboratory decontamination
Maintenance of laboratory equipment
Ordering laboratory consumables and maintain stock levels
Description of the unit
Oncology Research is accountable for the discovery of novel targets and drug projects related biology research in the therapy area of Oncology at Orion. Our teams build the R&D Oncology portfolio and Oncology strategy in close collaboration with business and all R&D global functions.
We offer
We are offering an excellent opportunity to work in a dynamic team in a modern laboratory facilities equipped with state-of-art laboratory instrument building up Oncology Research at Orion.
In Orion we have a highly interesting R&D pipeline and enthusiastic working environment with opportunities to use your own strengths to build your competence development. Appreciation of colleagues and continuous development are part of our core values. The culture of Orion R&D is informal and we enjoy working together.
Join us – together we build well-being and do work that we are proud of!
Requirements
In our team, it is important that you are not afraid to take responsibilities and you enjoy helping others. You are accurate and persistent in your work. Good communication and writing skills in English are needed and you work well with others. We hope you are excited of getting new tasks and developing yourself.
We wish that you have:
A Bachelor’s degree in Life Sciences or other related discipline
2 years of relevant laboratory experience
Experience working with mammalian cells and performing laboratory based Immune cellular assays
Excellent communication, interpersonal, and organizational skills
Possess basic IT skills, preferably experience with Microsoft Office, Graph Pad Prism and Flowjo
Flow cytometry and sample preparation for single cell RNA sequencing experience is an advantage
Industry experience is an advantage, but not a requirement
Additional information
Please send your CV and cover letter in English by 29th October 2023. We may start processing applications already during the application period, so please submit your application as soon as possible.
For further information, please contact Dr Anil Thotakura, Head of Immuno-Oncology, +358 50 966 7229. Best time to contact: 18th October 14:00 to 15:00 and 24th October 9:30 to 11:00 am.
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person.
Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.