Suomen Solubiologit ry

Accessioning Specialist – Blueprint Genetics

15.10.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3727036129

About the job

Are you systematic, organized and take pride in being meticulous even under time pressure? Are you interested in working in the core of production at the forefront of life sciences and healthcare? If you answered ”yes!”, keep reading!

Blueprint Genetics, a Quest Diagnostics company is a leading clinical genetic testing company aspiring to bring world-class genetic knowledge to mainstream healthcare. We want to improve the lives of individuals and families impacted by inherited diseases. Our Production Services Team is looking for an Accessioning Specialist to work at our sample reception in our Keilaniemi office in Espoo, Finland.

Job Description

As an accessioning specialist your primary task will be to review orders, perform sample reception and specimen accessioning and record sample information into our system. You confirm that samples arriving at our laboratory comply with our sample requirements and review the enclosed paperwork. You use your knowledge of our products and your background in life sciences to make sure the test choices are optimal for the customer’s needs. You take pride in being meticulous as your work as an accessioning specialist is very detail-oriented and guided by precise guidelines. Problem-solving skills are needed to apply those guidelines in practice for the diverse patient cases that are received by our laboratory. On a daily basis, you will have a chance to work closely with other awesome experts at Blueprint Genetics from customer support to clinical genetics.

Your Main Responsibilities Will Be

Reviewing orders, sample reception, and accessioning
Recording sample information in the Laboratory Information System
Performing quality control for clinical samples and clinical records
Examining requisitions to ascertain acceptability against established criteria
Investigating incomplete or unacceptable submissions
Organizing samples and paperwork per established protocol

Our ideal candidate

We hope that you are highly motivated to work in specimen accessioning and eager to learn more about our production processes. You take pride in having superior attention to detail and you are comfortable with following routines and processes. In order to ensure an uninterrupted production chain, our team works in shifts, including evenings and occasionally also on weekends. We value flexibility and the ability to work under pressure, as at times the work can get hectic due to a high level of incoming samples. Last but not least, we aspire to find a person who fits the inclusive, low-hierarchy, and positive culture of Blueprint Genetics!

Our Ideal Team Member Has

A Vocational or Bachelor’s degree preferably in life sciences or relevant field
Any specialization and/or prior experience in medical genetics and laboratory accessioning is an asset
Good proficiency in written and verbal communication skills in English. Finnish skills are seen as an advantage
Superior attention to detail, and a systematic approach to work
Good computer and data entry skills
Enthusiasm to learn more about our products and production processes, and a passion to develop them further
The ability to work in shifts (including evenings and occasional weekends)

What We Offer

The opportunity to work for a company that makes a real difference – Blueprint Genetics has a clear and motivating purpose to improve the lives of patients and families affected by inherited diseases
A positive, open, and international work environment with great people from different fields of expertise. We are a team of close to 300 experienced professionals, who collaborate to drive genetic knowledge forward
As an accessioning specialist you’ll become part of our crew of 20 dedicated, supportive and diverse professionals. You’ll be at the frontline of our operations and playing a key role in ensuring our production process runs smoothly and targets are met
Employee benefits such as participation to performance-based bonus payment system, extensive occupational healthcare with Heltti, sports, culture & wellbeing benefit, team events & office parties.

How To Apply

Please submit your application and CV latest on Oct 22nd, 2023. Interviews will start during the application period. We hope you join our team as soon as possible. The position is permanent and full-time.If you have any further questions about the position, you can turn to our Production Services Manager Iida Heikkilä by email: iida.heikkila@blueprintgenetics.com or by mobile +358 40 5899 017 on Tuesday October 3rd between 10 and 11 am EET and Thursday October 5th between 2 and 4 pm EET.

Who We Are

We are a specialty genetics and bioinformatics company focused on providing genetic testing for inherited diseases. We are based in Helsinki, with a customer base spanning over 70 countries. www.blueprintgenetics.comBlueprint Genetics is a Quest Diagnostics company. Quest Diagnostics is the world’s leading provider of diagnostic information services. www.questdiagnostics.comWe are changing diagnostics by providing accessible and actionable genetic knowledge in all medical specialties. Our mission is to support healthcare professionals around the world in providing the best care for patients and families with rare inherited diseases. We do that by delivering answers using fast, affordable, and comprehensive genetic diagnostics.

Posted on Sep 26, 2023.

Postdoctoral Researcher in Molecular Cancer Cell Biology and Genetics, Disease Networks Research Unit – Faculty of Biochemistry and Molecular Medicine, University of Oulu

15.10.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3733198082

About the job

The University of Oulu is one of the biggest and most multidisciplinary universities in Finland. We create new knowledge and innovations that help to solve global challenges. We offer you an international and inspiring working environment where you are given responsibility and can use your skills, develop yourself and do work that matters. Our flexible and family-friendly workplace makes it easy for you to balance work and leisure. The University of Oulu is ranked in the top 3% of the world´s universities.

Applications are invited for full-time

Postdoctoral Researcher

position for a maximum of four years, starting at the earliest on 01.01.2024 in a Biocenter Oulu research project ”The ECM control of the prostate cancer genome” led by Professors Aki Manninen and Gong-Hong Wei at the Disease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine.

Description Of The Project

The aim of our project is to characterize the molecular mechanisms by which the tumor microenvironment regulates the genome organization and epigenetic status of prostate cancer (PCa) cells. A specific focus will be put on the role of α6β4-integrins in mediating mechanical regulation of chromatin organization in the nucleus. The function of super enhancer regions harboring multiple PCa risk-associated genetic variations will be investigated in order to better understand how the region contributes to genomic regulation of PCa-promoting transcriptional programs.

The postdoctoral researcher will work together with our multinational team and will learn to utilize 3D cell culture models, prostate cancer patient-derived organoids, xenograft-mouse models, advanced microscopy techniques, viral CRISPR/Cas9-based genomic engineering as well as other molecular cell biology methods and functional genetics/genomics/bioinformatics approaches.

What we offer?

Exciting research project and excellent multidisciplinary research environment
The support of an experienced and enthusiastic team and broad scientific network where you can share your expertise and grow as an expert.
Development and career options of the big organization. FBMM is highly international (~50% of the roughly 200 employees at the faculty are international). Biocenter Oulu and the FBMM has put a great effort towards building a cutting-edge research infrastructure that includes state-of-the-art instrumentation for imaging, gene-modified mice, X-ray crystallography, and quantitative biochemistry. The Faculty has extensive collaborative national and international networks including Biocenter Finland and the ESFRI projects Instruct, EuroBioimaging, and Infrafrontier.
Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits.
Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu.
We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.

What we expect from you?

We are looking for ambitious, highly motivated candidates who have enthusiasm and ability to work hard both independently and as a team member to tackle challenging problems to achieve common goals.
Doctoral degree in a relevant field (must have been completed by 31.12.2023)
Documented experience in experimental research is required; previous experience in cell biology, cancer genetics, functional genomics or mouse model is appreciated but not essential
Ability to fluently communicate in English. Both spoken and written English skills are required.
All our researchers also teach. For postdoctoral fellows this typically means teaching/supervision in practical laboratory courses for undergraduates, supervision of doctoral students/undergraduates in the laboratory. Could also include lecturing.

Salary

The position is fixed-term for maximum of 4 years as of 01.01.2024 or as soon as possible thereafter.

The salary will be based on the levels 5-6 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 3600-4200 € per month (before taxes).

A trial period of 6 months is applied in the position.

How to apply?

Interested? If yes, please apply by 01.11.2023 (23:59 Finnish local time) through our recruitment system.

The application should be written in English and include the following:

Cover letter shortly describing your motivation to apply for this position
CV following the guidelines of the Finnish Advisory Board on Research Integrity
List of publications, following the guidelines of the Academy of Finland
Certificates/Diplomas
Contact information of two persons available for recommendation

The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview. All applicants will be notified during the selection process.

Contact Information

If you have any further questions, please contact Prof. Aki Manninen, email: aki.manninen(at)oulu.fi or Prof. Gong-Hong Wei, email: gonghong.wei(at)oulu.fi

Posted on Oct 4, 2023.

Two Doctoral Researchers in Molecular Cancer Cell Biology and Genetics, Disease Networks Research Unit – Faculty of Biochemistry and Molecular Medicine, University of Oulu

15.10.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3733197351

About the job

The University of Oulu is one of the biggest and most multidisciplinary universities in Finland. We create new knowledge and innovations that help to solve global challenges. We offer you an international and inspiring working environment where you are given responsibility and can use your skills, develop yourself and do work that matters. Our flexible and family-friendly workplace makes it easy for you to balance work and leisure. The University of Oulu is ranked in the top 3% of the world´s universities.

Applications are invited for two full-time

Doctoral researcher

positions for a maximum of four years, starting at the earliest on 01.01.2024 in a Biocenter Oulu research project ”The ECM control of the prostate cancer genome” led by Professors Aki Manninen and Gong-Hong Wei at the Disease Networks Research Unit, Faculty of Biochemistry and Molecular Medicine.

Description Of The Project

The aim of our project is to characterize the molecular mechanisms by which the tumor microenvironment regulates the genome organization and epigenetic status of prostate cancer (PCa) cells. A specific focus will be put on the role of α6β4-integrins in mediating mechanical regulation of chromatin organization in the nucleus. The function of super enhancer region harboring multiple PCa risk-associated genetic variants will be investigated in order to better understand how the region contributes to genomic regulation of PCa-promoting transcriptional programs.

The doctoral researchers will work together with our multinational team and will learn to utilize 3D cell culture models, prostate cancer patient-derived organoids, xenograft-mouse models, advanced microscopy techniques, viral CRISPR/Cas9-based genomic engineering as well as other molecular cell biology methods and functional genetics/genomics approaches.

What we offer?

Exciting research project and excellent multidisciplinary research environment
The support of an experienced and enthusiastic team and broad scientific network where you can share your expertise and grow as an expert.
Development and career options of the big organization.
Wellness benefit ePassi covering sport, culture and well-being. Read more about other staff benefits.
Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
Our Buddy Programme and Spouse Network support you and close-ones in settling into Oulu.
We have a HR Excellence in Research -quality label which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. Read more about living in Oulu.

What we expect from you?

A successful candidate is highly motivated and a curious mind
You must possess a Master’s degree or an equivalent degree (e.g. licentiate) preferably in molecular cell biology, biochemistry and molecular medicine, genetics, functional genomics or similar. Degree must have been completed with good grades by 31.12.2023.
All our researchers also teach. For Doctoral Researchers this typically means teaching/supervision in practical laboratory courses for undergraduates.
Successful candidate is expected to be collaborative and have good communication skills. Ability to pursue independent research and to communicate and write in English is also expected.

The selected candidates will carry out their doctoral studies in the Health and Biosciences Doctoral Programme of the University of Oulu Graduate School (UniOGS) and must meet the minimal requirements to receive doctoral study rights as defined in UniOGS requirements.

Salary

The positions are fixed-term for maximum of 4 years as of 01.01.2024 or as soon as possible thereafter.

The salary will be based on the levels 2-4 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component). Starting gross salary will be approx. 2300-2600 € per month (before taxes).

A trial period of 6 months is applied in the position.

How to apply?

Interested? If yes, please apply by 01.11.2023 (23:59 Finnish local time) through our recruitment system.

The application should be written in English and include the following:

Cover letter shortly describing your motivation to apply for this position
CV following the guidelines of the Finnish Advisory Board on Research Integrity
Certificates/Diplomas
Contact information of two persons available for recommendation

The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview. All applicants will be notified during the selection process.

Contact Information

If you have any further questions, please contact Prof. Aki Manninen, email: aki.manninen(at)oulu.fi or Prof. Gong-Hong Wei, email: gonghong.wei(at)oulu.fi

Posted on Oct 4, 2023.

Postdoctoral fellow – Lagerlöf Lab at Umeå University

15.10.2023 | Avoimet työpaikat

Lagerlöf Lab at Umeå University in Sweden is seeking a postdoctoral fellow excited to study how the brain regulates food intake. Our lab has fun, is supportive and loves the brain! It’s a position for 2 years where we have funding to extend it for longer. Several projects are available and candidates with different backgrounds are encouraged to apply. We want to support your career and help you take the next step towards your goals. Contact PI olof.lagerlof@umu.se or apply directly through https://tinyurl.com/n8unycet.

Postdoctoral Researcher for Translational Immunology Research Program – University of Helsinki

16.9.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3702460183

About the job

Eliisa Kekäläinen’s research group “Inborn and acquired immunodeficiencies” at the Translational Immunology Research Program at University of Helsinki, Faculty of Medicine invites applications for the position of

POSTDOCTORAL RESEARCHER

Our research group focuses on the human thymus which produces key immune cells, the T cells. We 1) evaluate and develop methods to better measure thymopoiesis, 2) study how thymopoiesis and the thymus itself is affected by viral infections, and 3) aim to understand how and why certain autoimmune diseases, such as myasthenia gravis, develops. We use thymic tissue samples from both immunologically healthy individuals and patients with cutting edge techniques including thymic organ cultures and different multi-dimensional single-cell methods to dissect the normal and pathological processes in the thymus. We are seeking for a motivated post-doctoral researcher to work on Research Council of Finland – funded project.

Qualifications

Applicants with a doctoral degree and strong background in immunology or other relevant life science fields who are interested in working in an inter-disciplinary environment are particularly encouraged to apply. Applicant must be able to work independently and have good communication skills in English. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.

The person we are looking for has:

effective communication and collaboration skills
proven track record in designing and executing experimental science
motivation and determination to learn (more) immunology

Furthermore, if you have experience with the topics below, we would love to hear about your

supervision experience
working with tissue samples or organoid cultures
experience in flow cytometry, single-cell omics, CRISPR-Cas or immunohistochemistry

What We Offer

The appointment will be initially for two years starting from January 2024 (possibility to start earlier or later if needed). Trial period of six months will be applied. The monthly gross salary will be appr. 3200-3600 € per month depending on the appointee’s qualifications and experience. In addition, University of Helsinki offers comprehensive services to its employees, including occupational health care and opportunities for professional development. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .

We offer you on top of these benefits an opportunity to explore and learn in a team that shares a passion for immunology. The team’s well-being is top priority in our laboratory.

How To Apply

Please submit your application as a single PDF file containing your CV, a publication list where you describe your own role in the publications that you consider the most relevant for the position, and two letters of reference. The application will be submitted through the University’s electronic recruitment system by clicking “Apply now” link. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi. The deadline for applications is 30 October 2023. Applications will be considered on a rolling basis until a suitable candidate is found.

For further information on the position, please contact Eliisa Kekäläinen (eliisa.kekalainen(at) helsinki.fi).

For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk (at) helsinki.fi).

Selected publications from Kekäläinen lab:

Hetemäki I, Kaustio M, Kinnunen M, Heikkilä N, Keskitalo S, Nowlan K, Miettinen S, Sarkkinen J, Glumoff V, Andersson N, Kettunen K, Vanhanen R, Nurmi K, Eklund KK, Dunkel J, Mäyränpää MI, Schlums H, Arstila TP, Kisand K, Bryceson YT, Peterson P, Otava U, Syrjänen J, Saarela J, Varjosalo M, Kekäläinen E. Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells. Sci Immunol. 2021 Nov 26;6(65):eabe3454. doi: 10.1126/sciimmunol.abe3454.

Sarkkinen J, Dunkel J, Tuulasvaara A, Huuskonen A, Atula S, Kekäläinen E, Laakso SM. Ectopic germinal centers in the thymus accurately predict prognosis of myasthenia gravis after thymectomy. Mod Pathol. 2022 Sep;35(9):1168-1174. doi: 10.1038/s41379-022-01070-2.

Kleino I, Nowlan K, Kotimaa J, Kekäläinen E. Optimising protein detection with fixable custom oligo-labelled antibodies for single-cell multi-omics approaches. Biotechnol J. 2022 Jun;17(6):e2100213. doi: 10.1002/biot.202100213.

Nguyen NA, Huang X, Cabrera LE, Pekkarinen PT, Nowlan K, Strandin T, Kantele A, Vapalahti O, Heinonen S, Kekäläinen E. A comprehensive assessment of four whole blood stabilizers for flow-cytometric analysis of leukocyte populations. Cytometry A. 2023 Apr;103(4):313-324. doi: 10.1002/cyto.a.24700. Epub 2022 Nov 1. PMID: 36279192.

Lusila P, Toivonen A, Jarva H, Vettenranta K, Lehtimäki S, Kekäläinen E. FASCIA Method in the Assessment of Lymphocyte Mitogen Responses in the Laboratory Diagnostics of Primary Immunodeficiencies. J Clin Immunol. 2023 Apr;43(3):653-661. doi: 10.1007/s10875-022-01417-z.

The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.

The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.

Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.

Postdoctoral researcher in neuroscience and/or human stem cell based neuronal models – University of Helsinki

16.9.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3706052115

About the job

INVITATION FOR APPLICATIONS

Postdoctoral researcher

We are looking for a skilled postdoctoral fellow with a background in neuroscience and/or human stem cell based neuronal models at the Institute for Molecular Medicine Finland FIMM , Helsinki Institute of Life Science, HiLIFE in the research groups of Professor Aarno Palotie ( Research Group Palotie ) and Dr. Olli Pietiläinen ( Research Group Pietiläinen ). The position is part of a research program that aims to discover biological mechanisms in schizophrenia and related neuropsychiatric disorders. The program bridges multidisciplinary group of researchers in the interface of genetic discoveries and multi-omic molecular biology using cell collections from over 6000 sequenced participants. The project combines state-of-art functional genomics and experimental cell biology approaches in human stem-cell derived neuronal models to discover how genetic risk factors identified in the disorders mediate their causative effects in human cells. The Pietiläinen laboratory is based at the Neuroscience Center and has close links with the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard ( https://www.broadinstitute.org/stanley ). The Pietiläinen group is located at the Meilahti biomedical campus in Helsinki and is closely linked with research groups at the HiLIFE Institute for Molecular Medicine https://www.helsinki.fi/en/hilife-fimm (HiLIFE-FIMM) and the Faculty of Biological and Environmental Sciences https://www.helsinki.fi/en/faculty-of-biological-and-environmental-sciences . HiLIFE-NC offers a inspiring environment to solve fundamental challenges of brain functions as part of the multidisciplinary HiLIFE infrastructure https://www.helsinki.fi/en/helsinki-institute-of-life-science at the university of Helsinki. In Pietiläinen group you will be part of a striving scientific community utilizing state of the art technologies in genomics and cell biology for scientific discoveries of the brain.

Role description:

We are seeking a postdoctoral researcher to work on a multidisciplinary project that utilizes human induce pluripotent stem cells (iPSC) to model cellular processes involved in neuropsychiatric disorders. The primary goal is to use known genetic risk variants to identify quantifiable cellular phenotypes that underlie neuropsychiatric disorders. To this end we apply high-throughput multiple omics approaches such RNA sequencing and proteomics that are complemented by experimental molecular cell biology approaches in the in vitro model systems, including cellular assays and gene editing techniques in isogenic cell lines. We are looking for a person for planning, conducting, and co-supervising molecular biology and cellular experiments in human iPSCs.

Key Requirements

We are looking for a highly motivated and creative person with a primary interest in molecular cell biology using human iPSC derived neuronal models to discover mechanisms in neurological disorders, and to work in multidisciplinary team of clinical, wet lab, and computational scientists. Candidates should have a PhD in neuroscience or molecular and cell biology with experience in iPSC derived neuronal models. We require previous experience and skills in cell culture, molecular cell biology, iPSC models, and neural differentiation. The ideal candidate will have experience in these areas, and an interest in translating genetic discoveries into functional biology. Any previous experience in analysing and processing genomic and omic data is considered an advantage. The position is available from September 2023 onwards, or earlier, if required. It is a two-year fixed-term position, with a possibility of extension. Trial period of 6 months will be applied.

The salary will be based on level 5 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance with the overall starting salary amounting to approximately 3600-4500 EUR per month, depending on the qualifications and previous relevant research experience of the candidate.

Please submit your application via the University of Helsinki Recruitment System by clicking the ‘Apply for the position button’ below. If you need support with the recruitment system, please contact recruitment@helsinki.fi.

Please attach the following documents to your application as a single PDF file:

CV (including publications)
cover letter (maximum 1 page) that details your past experience and motivation
contact details of at least two references

The deadline for applications is September 29th, 2023. Interviews will be conducted either in person or online. For more information on the position, please contact Dr. Olli Pietiläinen (olli.pietilainen@helsinki.fi).

University of Helsinki

The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.

Helsinki Institute of Life Science

Helsinki Institute of Life Science (HiLIFE) is a new institute established in 2017 that supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.

Institute for Molecular Medicine Finland

The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki – a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community

HiLIFE -Neuroscience Center

The Neuroscience Center is an international research unit within Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki, a leading Nordic university with a strong commitment to life science research. The research focus of NC is on translational brain plasticity. We carry out research relevant for the human brain both in health and disease, and during development and aging, by applying versatile approaches and modern technology platforms. NC aims at making fundamental discoveries about brain functions and especially translate research findings into improvements in the treatment, prevention and diagnosis of psychiatric and neurological disorders. The research in NC spans across several scales from stem cell research and molecular neuroscience to systems and cognitive neuroscience in both animal and human models.The research groups of NC conduct research in neuroscience at the highest international level and actively apply the results for the benefit of the society. NC collaborates actively with other units of HiLIFE and faculties of the University of Helsinki, Helsinki University Central Hospital, and Neurocenter Finland.

Research Director/Senior Researcher, Translational Cardiovascular Research – University of Eastern Finland, Kuopio

16.9.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3713876254

About the job

The University of Eastern Finland is inviting applications for a part time (40 %) Research Director/Senior Researcher position at the Kuopio Campus. The position will be filled for a three-year term from 1 November 2023 onwards (or as agreed). Please find more information below and submit your application by 2 October 2023.

Role and salary

We are seeking talented researchers to develop new treatment strategies and gene therapy approaches to cardiovascular diseases by using preclinical and/or clinical research in cooperation with the Kuopio University Hospital (KYS). Your work will have a significant impact on the field of cardiovascular research and will help us develop new approaches to preventing and treating these devastating diseases. We are looking for passionate and self-driven individuals to contribute to strengthening UEF’s strategic profile in cardiovascular diseases.

As our new Research Director/Senior Researcher, you will be working at the A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences. The position is located in Kuopio, Finland.

Our Cardiovascular Research Community is a world leader in conducting gene therapy trials for the treatment of ischemic cardiovascular diseases, in pre-clinical and translational studies, and in manufacturing GMP-compliant gene medicines. This position is intended to further this research and to have a significant impact on the field of translational medicine that will help us develop effective strategies for personalised prevention, diagnostics, monitoring, and treatment of chronic cardiovascular diseases.

As our new Research Director/Senior Researcher in Cardiovascular Research, you will work as an expert within the Cardiovascular Research Community. The responsibilities will also include the supervision of doctoral dissertations, possibly teaching, and the acquisition of external funding.

The position will be filled for a part-time (40 %) three-year term from 1 November 2023 onwards (or as agreed). The position will be filled for a fixed term due to it pertaining to tasks connected to UEF Multimodal Approaches and Data Analytics in Translational Medicine development. A probationary period is applied to all new members of the staff.

The salary of the position is determined in accordance with the salary system for Finnish universities. The salary comprises two components: a job-related salary element and a personal salary element. In this position, the job -related salary element is €3673.96 – 4235.52 /month, based on levels 6–7 of the job requirement level chart for teaching and research staff. The personal salary element can be a minimum of 6 % and a maximum of 50 % of the above-mentioned sum.  Depending on the job-related salary element and the personal salary element, the salary (40 %) will be approximately from €1616 – 2152 /month at the beginning of the employment relationship.

Our requirements and expectations

Requirements

a doctoral degree in a relevant field and a medical degree (licenced to practise medicine in Finland)
a strong track record of research in translational preclinical animal models and/or cardiovascular diseases
excellent/good skills in spoken and written English. English is used as the language of instruction and supervision in this position.
experience in externally funded research projects, an independent approach to conducing research.

Expectations/advantages

Being active in clinical practice
Expertise in viral vectors
Specialization in cardiology
Project management skills
Supervisory and teaching skills necessary for the position
Experience in international research cooperation
Collaboration skills
A positiven attitude

Your benefits

You will have access to the university’s staff benefits, including

opportunity for flexible multi-location work
extensive occupational health care
broad selection of staff training
staff discount on lunch in our campus restaurants, as well as on a range of other services
affordable sports services and tax-free bike benefit

Please read more in the Work at UEF section on our website.

You will have an opportunity to work in an interesting and meaningful role as part of our international, creative, participatory and inclusive academic community.

Enjoy your life in Finland! Known for its cleanliness, welfare know-how, modern technology and superb education system, Finland is an exotic and safe country to work in. Please visit the Life in Finland section on our website to learn more.

How to apply?

Submit your application by using our electronic application form no later than 2 October 2023 by 24:00 (midnight) Finnish time (UTC+3)

Please note that you must include the following appendices in your application

CV (https://tenk.fi/en/advice-and-materials/template-researchers-curriculum-vitae)
a list of publications (https://www.aka.fi/en/research-funding/apply-for-funding/how-to-apply-for-funding/az-index-of-application-guidelines2/list-of-publications/)
copies of your academic degree certificates / diplomas, and copies of certificates / diplomas relating to your language proficiency, if not indicated in the academic degree certificates/diplomas
motivation letter: A detailed letter explaining your interest in the project, how you believe you can contribute to our objectives, and why you consider yourself a strong fit for the role
Names and contact information for 2 referees
Other documents to demonstrate the applicant’s merits for the position.

Questions?

For further information on the position, please contact Professor Seppo Ylä-Herttuala, tel. +358 40 355 2075, seppo.ylaherttuala@uef.fi and Research Director Nihay Laham Karam, tel. +358 29 445 4157, nihay.laham-karam@uef.fi

For further information on the application procedure, please contact HR-secretary Tarja Salmi, tarja.salmi@uef.fi, +358 29 4458220

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 3 090 degree students and about 580 PhD students in the Faculty. The faculty has 800 staff members.

The University of Eastern Finland, UEF, is one of the most multidisciplinary universities in Finland. We have a staff of 3,200 members, and our academic community comprises around 16,000 degree students. Our campuses are located in Joensuu and in Kuopio. Our research is ranked among the best in the world in several fields. We generate research-based knowledge and make it openly accessible for the benefit of all. To learn more about our university please visit our website at  www.uef.fi/en. On our website, you’ll also find information about the university as a work community and as an employer (https://www.uef.fi/en/article/one-university-a-thousand-stories), as well as our employees’ career stories (https://www.uef.fi/en/career-stories).

Doctoral Researcher in Molecular Microbiology and Bioinformatics – University of Oulu

16.9.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3714809223

About the job

The University of Oulu is one of the biggest and most multidisciplinary universities in Finland. We create new knowledge and innovations that help to solve global challenges. We offer you an international and inspiring working environment where you are given responsibility and can use your skills, develop yourself and do work that matters. Our flexible and family-friendly workplace makes it easy for you to balance work and leisure. The University of Oulu is ranked in the top 3% of the world´s universities.

We are now seeking a highly motivated

Doctoral Researcher

in molecular microbiology and bioinformatics to join us in the Ecology and Genetics research unit at the Faculty of Science.

Description Of The Project

The plant-produced one-carbon compounds, such as methane and methanol, are an abundant energy source supporting a vast community of methylotrophic microbes living on aboveground plant surfaces and in the internal plant compartments (endophytes, endosphere). The Academy Research Fellow project ”Methanotroph communities filtering methane produced by coniferous forest trees” aims to characterize the lifestyle of the methane-consuming bacteria living inside pine trees.

We will utilize metagenomics to identify bacterial communities that filter methane in the aboveground tissues of pine and to analyze the functional characteristics (genes, pathways) associated with the lifestyle. We will use fluorescent markers with cutting-edge microscopy and imaging techniques to study the colonization dynamics between pine hosts and key methanotrophs. Finally, we will analyze how these endophytic methane-consuming bacteria will affect the methane emissions of the pines. The project will bring new significant knowledge on the role and dynamics of methane in plant-microbe interactions in forest ecosystems.

As a Doctoral Researcher, you will perform laboratory experiments to isolate and identify new microbial species, design and create fluorescent strains for microscopy, and handle and analyze metagenomic sequencing data. Thus, solid skills and knowledge in microbiological or molecular biological laboratory work and bioinformatics are required. During the project, the Doctoral Researcher will gain comprehensive knowledge and hands-on experience in establishing and running scientific experiments involving plants and microbes. Also, the candidate will learn how to analyze the outcomes by utilizing various bioinformatics and image analysis techniques in collaboration with the research team. The Doctoral Researcher will benefit from international visits to labs or research partners out of Finland during the project.

The research will be conducted at the Ecology and Genetics Research Unit, University of Oulu. The unit has a vibrant research community with strong in-house expertise in plant-microbe research and microbial ecology in general. We have excellent microbiology and molecular biology laboratories and instrumentation concerning the project’s needs. The candidate will join the University of Oulu Graduate School (UniOGS), which provides the framework and conditions for high-quality, research-driven doctoral training.

You are the person we are looking for if you have:

A master’s degree, or be about to obtain one, in microbiology, molecular genetics, microbial bioinformatics, or another related field (the degree must be completed before starting the position)
High motivation and the ability to work efficiently both independently and as part of a team
Solid background knowledge in microbial genetics and genomics
Experience in conducting laboratory work by utilizing tools in molecular biology or microbiology
Previous experience in microbial bioinformatics, e.g., metagenomics, bacterial WGS, or amplicon sequencing, is considered an advantage
Fluent in written and spoken English
See also the requirements of the University of Oulu Graduate School

What we offer?

An ambitious and exciting research project that aims to answer globally significant research problems
You will become a part of a highly talented research group, that is working on strategically and globally significant research area.
You will receive support from your team and supervisor, so that you can excel in your research.
In addition to modern research facilities, we offer you personnel benefits such as free occupational healthcare, wellness benefit ePassi covering sport, culture, and well-being, and endless opportunities to develop your skills and competencies. Read more about other staff benefits.
Development and career options of the big organization.
Work that matters and a workplace that promotes flexibility and work-life balance. Read more about working with us.
Our Buddy Programme and Spouse Network support you and close ones in settling into Oulu.
We have an HR Excellence in Research -quality label, which is a recognition awarded by the European Commission for the development of researchers’ working conditions and careers.
Finland is one of the most livable countries in the world, with a high quality of life, safety, an excellent education system, and a competitive economy. Read more about living in Oulu.

Salary

The Doctoral Researcher position in the project is fixed term for 3.4 years and scheduled to be filled from October 2023 or as soon as possible thereafter.

The salary will be based on levels 2 – 4 of the demand level chart for teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (a maximum of 50 % of the job-specific component). The starting gross salary will be approx. 2300-2600 € per month (before taxes). A trial period of 6 months is applied for the position.

How to apply?

Interested? If yes, please apply by 15th of October, 2023 (23:59 Finnish local time) through our recruitment system

The application should be written in English and include the following documents in PDF format:

Motivation letter (max. 2 pages) – summarizing the applicant’s professional experience and expertise and describing why the applicant is interested in this position. Also, information on personal research interests, experience, and career goals is valuable to provide here
CV – following the guidelines of the Finnish Advisory Board on Research Integrity. The CV should include the contact information of two senior/experienced researchers who can provide reference letters
Certificates/Diplomas – scanned electronic copies of certificates and transcripts of the records of relevant previous degrees (MSc and BSc or equivalent). If the original documents are not in English/Finnish, each document must be accompanied by a certified translation into English

The eligible applicants fitting best in the profile expected for the position will be invited to an on-site or remote interview. All applicants will be notified during the selection process.

Contact Information

If you have any further questions, please contact Academy Research Fellow Janne Koskimäki, Ecology and Genetics Research Unit, Faculty of Science, University of Oulu, janne.koskimaki@oulu.fi

Doctoral Researcher in the Systems Immunometabolism Lab – University of Helsinki

16.9.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3719157280

About the job

The Research Program Unit at the Faculty of Medicine, University of Helsinki invites applications for

a fixed-term, full-time Doctoral Researcher position.

The position is available from October 2023, with flexibility on the starting date, and extends until August 2027.

The Chen’s research group at University of Helsinki is seeking a motivated doctoral researcher to contribute to a core project funded by the Academy of Finland. The project aims to investigate the role of RNA splicing and tissue environment in shaping human macrophage diverse phenotypes during obesity. In this study, we will use cutting-edge single-cell and spatial omics technologies, develop novel computational methods, perform multimodal data analysis and integration, and experimental validation to uncover key factors steering the progression of obesity-associated metabolic disorders. The selected candidate will play a pivotal role in computational data analysis and method development. Individuals with a strong interest and background in computational biology/bioinformatics are strongly encouraged to consider this opportunity.

As the global concern over obesity escalates due to its significant contribution to various diseases, your work will enhance our understanding of novel cellular and molecular mechanisms driving the emergence of obesity-associated metabolic disorders. Join us in this pivotal endeavour to advance our understanding and address the pressing health challenges posed by obesity.

Qualifications

Eligibility requires a master’s degree in computational biology/bioinformatics or a relevant field. Proficiency in programming and a fervent curiosity to employ data science in deciphering biological mechanisms of human diseases are imperative. Candidates should exhibit adeptness in both independent work and collaborative team settings across diverse disciplines. Motivation, excellent time management, and effective communication skills in spoken and written English stand as essential attributes. Additionally, familiarity with immunology, metabolism, and RNA biology will be advantageous.

The starting salary will be set on level 2 of the national salary scale for teaching and research personnel at Finnish universities. In addition, salary component based on personal performance will be paid. The starting salary will be in the range of 2300-2600 euros/month (pre-tax). A six-month trial period will be applied.

Finland stands out as one of the world’s most liveable nations, boasting exceptional quality of life, safety, and renowned education system. The selected candidate will receive University of Helsinki staff benefits, including occupational health care services. Additionally, access to high-quality public childcare services, schools, and substantial family benefits is provided. The selected candidate will be based in Finland while employed by the University of Helsinki.

How To Apply

Application should include the following documents as a single pdf file in English:

A motivation letter detailing your prior knowledge, research interests, career goals, and compelling rationale for your suitability for this role.
A Curriculum Vitae, including a list of publications and contact details of 2 referees.
Certificates/Diplomas: Please provide scanned copies of diplomas and transcripts of your previous degrees. In instances where the original documents are not in English, Finnish, or Swedish, please provide an official certified translation into either English or Finnish.

To apply, the applications should be submitted through the University of Helsinki Recruitment System via the link ”Apply now” below. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi. The closing date for applications is 16 October 2023 (at 23.59 EEST). Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .

For further information on the position, please contact Dr. Ping Chen (ping.chen (at)helsinki.fi).

For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk(at) helsinki.fi).

The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.

The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.

Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.

Postdoctoral Researcher for Translational Immunology Research Program – University of Helsinki

16.9.2023 | Avoimet työpaikat

https://www.linkedin.com/jobs/view/3702460183

About the job

Eliisa Kekäläinen’s research group “Inborn and acquired immunodeficiencies” at the Translational Immunology Research Program at University of Helsinki, Faculty of Medicine invites applications for the position of

POSTDOCTORAL RESEARCHER

Our research group focuses on the human thymus which produces key immune cells, the T cells. We 1) evaluate and develop methods to better measure thymopoiesis, 2) study how thymopoiesis and the thymus itself is affected by viral infections, and 3) aim to understand how and why certain autoimmune diseases, such as myasthenia gravis, develops. We use thymic tissue samples from both immunologically healthy individuals and patients with cutting edge techniques including thymic organ cultures and different multi-dimensional single-cell methods to dissect the normal and pathological processes in the thymus. We are seeking for a motivated post-doctoral researcher to work on Research Council of Finland – funded project.

Qualifications

Applicants with a doctoral degree and strong background in immunology or other relevant life science fields who are interested in working in an inter-disciplinary environment are particularly encouraged to apply. Applicant must be able to work independently and have good communication skills in English. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.

The person we are looking for has:

effective communication and collaboration skills
proven track record in designing and executing experimental science
motivation and determination to learn (more) immunology

Furthermore, if you have experience with the topics below, we would love to hear about your

supervision experience
working with tissue samples or organoid cultures
experience in flow cytometry, single-cell omics, CRISPR-Cas or immunohistochemistry