Ajankohtaista

Doctoral Researcher in Super-Resolution Microscopy and Microbiology

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The University of Helsinki is one of the world’s leading universities for multidisciplinary research. HiLIFE Helsinki Institute of Life Science is a research institute that supports high quality life science research across the University campuses and faculties. The research activities at the Institute of Biotechnology consist of several research teams focusing on a specific area of molecular biology, cell biology or biotechnology. For more information, please visit https://www.helsinki.fi/en/hilife-institute-of-biotechnology.

TEMPADAPT (Single-molecule visualization of temperature adaptation in sub-cellular dynamics and organization across bacteria) is a 5-year ERC-funded project in the laboratory of Jarno Mäkelä at the Institute of Biotechnology, from 2023 onwards. The project will aim at understanding temperature adaptation at the single molecule level in live bacteria. We will study bacteria thriving at 0°C (psychrophiles), moderate temperatures (mesophiles), and high temperatures  up to 100°C (thermophiles). In addition to state-of-the-art super-resolution microscopy, the project will apply single-cell perturbations, machine learning and modelling to analyze, integrate, and make sense of single-cell and molecule level data. 

The HiLIFE – Institute of Biotechnology, Mäkelä laboratory of Temperature Adaptation in Bacteria, invites applications for a position of

A Doctoral Researcher in Super-Resolution Microscopy and Microbiology

starting from January 2023, or as agreed. The PhD researcher will be offered up to 4-year fully funded contract.

Position description

We are looking for an enthusiastic and motivated doctoral researcher, who is interested in super-resolution microscopy and single-particle tracking, to join our research group for an ERC-funded project. The project involves planning and executing experimental work including state-of-the-art microscopy, genetic engineering, RNA-sequencing, data analysis, machine learning, and modelling to unravel how bacteria adapt to different temperatures. Our team will work on multiple topics at the interface of physics, chemistry, and biology: intracellular spatial organization, macromolecular crowding, liquid-liquid phase separation, heat- and cold shock protein dynamics, and gene regulation. 

The appointee is expected to work full time on the Ph.D. thesis and to complete the thesis and the associated studies in four years. The successful applicant will apply to be a Ph.D. student in the appropriate Faculty. The Ph.D. degree consists of the student’s research project resulting in peer-reviewed publications, studies specific to the research field, as well as transferable skills training.

Selection criteria

A successful candidate will have a MSc or equivalent in biology, biophysics, computational biology, or other relevant fields, and has demonstrated a keen interest in quantitative approaches. Previous experience in ‘wet’ lab work, genetic engineering, microbiology, fluorescence microscopy, Python/R/Matlab coding, bioinformatics, or data analysis is considered an advantage. Excellent communication and writing skills in English and ability to work both independently and collaboratively as part of a multidisciplinary international team are expected. The candidate should have outstanding organization and time management skills.

Salary and benefits

The starting salary of the doctoral researcher will be 2400-2600 euros/month, depending on the appointees’ qualifications and experience. A trial period of 6 months will be applied. The University of Helsinki offers comprehensive services to its employees, including occupational health care, support in access to high quality sports facilities, and vast opportunities for professional development.

How to apply

Please submit your application as a single pdf file, which includes the following documents in English: 
•    A motivation letter including a description of your research interests (max 1 page) 
•    CV (max 2 pages) including a list of publications

Include also contact information of two persons who are willing to provide a reference letter by separate request. Please submit your application, together with the required attachment, through the University of Helsinki electronic recruitment system by clicking on the ‘Apply for job’ button. Internal applicants (i.e., current employees of the University of Helsinki) submit their applications through the SAP Fiori portal.

The deadline for the applications is 22nd of December, but the position will be filled once a suitable candidate has been identified.

For more information, please contact the Principal Investigator Jarno Mäkelä (jarno.p.makela(at)helsinki.fi) or visit our lab website.

Why work with us?
Finland is a member of the EU, has high quality free schooling (also in English), generous family benefits and healthcare, and was recently ranked as the best country in the world for expat families and in the world’s top ten most livable cities. Finland and the Helsinki region possess top expertise in sciences in terms of a vibrant talent pool, leading research, strong support services and functioning collaboration networks. For more information about working at the University of Helsinki and living in Finland, please see helsinki.fi/en/university/working-at-the-university

Helsinki Institute of Life Science
Helsinki Institute of Life Science (HiLIFE) is a new institute established in 2017 that supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.

University of Helsinki
The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.

Scientist – Senior Scientist

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About the job

Global Preclinical CRO Seeking Scientists and Senior Scientists with Experience in Ophthalmic Drug Discovery

Experimentica Ltd. is seeking Scientists and Senior Scientists to complement their team at multiple locations, including Kuopio (Finland), Vilnius (Lithuania) and Fort Worth, TX (USA).

We are seeking individuals with proven experience in preclinical biomedical sciences and experience with rodent models for ophthalmic diseases and ocular pharmacology. Candidates will apply their scientific and leadership skills in support of colleagues and projects focused on the discovery of novel therapeutics for ocular diseases. The ideal candidate is someone who is flexible and excited to be a part of a collaborative, fast-paced biotechnology company committed to improving the lives of patients through accelerating the preclinical drug discovery pipelines of our Sponsors.

Responsibilities

In support of our In Vivo Pharmacology teams, develop and execute laboratory work, plans/schedules independently following division/site performance standards and metrics. Techniques may include any or all of the following:

• Perform various types of preclinical ocular safety and efficacy studies in preclinical laboratory animal species
• Author technical documents, such as study protocols, study reports, and operating procedures
• Review technical documents for accuracy, thoroughness, and compliance
• Supervise technical staff, including work assignments and performance management
• Communicate with customers
• All other duties as assigned.

Qualifications

Education: M.S., D.V.M. or Ph.D. in Biology, Molecular Biology, Biochemistry, Neuroscience, Pharmacology or related field

Experience: Masters with 2-4 years of relevant experience preferred, Doctorate Degree with 0-2 years of relevant experience preferred.

Knowledge/Skills Requirements

• Maintain high quality laboratory documentation in accordance with applicable regulatory guidance and site SOPs
• Develop and execute complex procedures or methods with high quality
• Becoming familiar with drug development milestones and their context
• Excellent written and verbal communications skills with internal and external customers
• Supervisory skills are expected for Scientists with direct reports
• Lead by example according to Experimentica’s values and culture
• Strategy is focused on personal and team time management and efficiency
• Well-organized with ability to multitask
• Ability to work effectively under pressure to meet deadlines
• Familiarity with safe and efficient laboratory practices
• Eagerness to be part of a fast-growing, global Contract Research Organization that helps improve patient lives by accelerating preclinical drug discovery for ocular diseases

About us

Experimentica is a global preclinical contract research organization helping sponsors from pharma, biotech, and academia accelerate their drug discovery and development efforts for ophthalmic disorders with an urgent unmet clinical need. Headquartered in Kuopio, Finland, we support our global client base from laboratories in Fort Worth, TX, DeKalb, IL, Vilnius, Lithuania and our Business Development team in Marseille, France.

Experimentica Ltd. is an equal opportunity employer that is committed to diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other protected characteristic as outlined by federal, state, or local laws. This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship. Experimentica Ltd. makes hiring decisions based solely on qualifications, merit, and business needs at the time. For more information, please contact us: info_us@experimentica.com

To apply

Please submit your resume and cover letter to careers@experimentica.com referencing job #22-03.

Tutkijatohtori, solu- ja molekyylibiologia – Jyväskylän yliopisto

https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=2&id=000014291&lang=fi

Haemme Jyväskylän yliopiston Bio- ja ympäristötieteiden laitokselle

TUKIJATOHTORIA, SOLU- JA MOLEKYYLIBIOLOGIA

alkaen 2.1.2023, tai sopimuksen mukaan, kahden vuoden määräajaksi.

Etsimme motivoitunutta tutkijaa työskentelemään akatemiatutkija Heikki Takalan tutkimusryhmässä Emil Aaltosen Säätion rahoittamassa projektissa, jossa kehitellään optogeneettista työkalua. Tämä työkalu perustuu erään valoreseptoriproteiinin, fytokromin toimintaan, ja se mahdollistaa punaisella valolla kontrolloidun geenien ilmentämisen nisäkässoluissa. Projekti sisältää optogeneettisen työkalun suunnittelua, kloonausta sekä testaamista nisäkässoluissa eri valotusolosuhteissa. Lisäksi projektissa tutkitaan työkalun fytokromikomponentin toimintaa biokemiallisilla menetelmillä.

Olet etsimämme henkilö, jos sinulla on tohtorin tutkinto soveltuvalta alalta ja kokemusta solubiologian perusmenetelmistä (nisäkässoluviljely, mikroskopointi, solujen karakterisointi)

Tutkijatohtorin tehtävistä, kelpoisuusvaatimuksista ja kielitaidosta määrätään yliopiston johtosäännössä ja kielitaito-ohjeistuksissa. Tehtävässä vaaditaan hyvää suomenkielen taitoa. Tohtorin tutkinto tulee olla suoritettu ennen tehtävässä aloittamista.

Mitä tarjoamme?

Jyväskylän yliopistossa olet arvostettu yliopistoyhteisön jäsen, jossa saat mahdollisuuden vaikuttaa kansainväliseen tutkimukseen. Pääset osaksi kansainvälistä ja monitieteistä yhteisöämme, jossa jokaisen hyvinvointi on tärkeää. Tarjoamme kampuksella ja sen läheisyydessä hyvät puitteet liikkuvaan ja hyvinvoivaan elämäntapaan.

Tutkijatohtorin tehtäväkohtainen palkanosa määräytyy yliopistojen palkkausjärjestelmän opetus- ja tutkimushenkilöstön tehtävien vaativuustason 5-6 mukaan. Palkkasi on noin 3300 – 3900 euroa kuukaudessa riippuen aiemmasta osaamisestasi ja kokemuksestasi. Tehtävän alkaessa käytetään kuuden kuukauden koeaikaa. 

Hakeminen

Hakemuksiin tulee liittää seuraavat liitteet:

1. Ansioluettelo (CV), joka laaditaan hyvää tieteellistä käytäntöä noudattaen sekä ottaen huomioon mahdollisuuksien mukaan ansioluettelomalli (ks. TENK:n ohje). Ansioluetteloon pitää liittää myös kahden akateemisen suosittelijan yhteystiedot.
2. Lyhyt hakemuskirje sisältäen hakijan tutkimusintressit.
3. Julkaisuluettelo. 
4. Tutkintotodistukset.

Hakemus tulee jättää viimeistään 31.12.2022 sähköisellä hakulomakkeella. Käsittelemme kaikki sähköisen järjestelmän kautta jätetyt hakemukset ja olemme hakijoihin yhteydessä hakuprosessin edetessä. 

Lisätietoja antaa akatemiatutkija Heikki Takala, heikki.p.takala@jyu.fi.
 

Bio- ja ympäristötieteiden laitoksen tutkimuksen vahvuusalat ovat evoluutiobiologia, luonnonvarojen ja ympäristön tutkimus sekä biologinen nanotiede. Laitoksen Ambiotica-rakennus kuuluu kiinteästi Jyväskylän Yliopiston Ylistönrinteen matemaattis-luonnontieteellisen tutkimuksen kompleksiin, jossa, kemian, fysiikan ja nanotieteiden laboratorioiden lisäksi, sijaitsee laadukkaat ekologian ja ympäristötieteen laboratoriot ja koetilat biologisiin ja kemiallisiin analyyseihin sekä erittäin motivoitunutta laboratoriohenkilökuntaa. LaserLab NSC kuuluu Nanotiedekeskukseen ja tarjoaa kansainvälisesti korkean tason laitteiston tutkimuksen tekemiseen.

Jyväskylän yliopiston 2500 asiantuntijan ja 14 500 opiskelijan ihmisläheisestä yhteisöstä jokaisen on helppo löytää paikkansa. Meille on tärkeää, että yhteisömme jäsenet voivat hyvin ja heillä on mahdollisuudet kasvaa ja kehittyä. Kaunis puistokampuksemme sijaitsee Jyväskylän keskustassa. Yliopisto on Keski-Suomen kolmanneksi suurin työnantaja.

Imaging Scientist /Biochemist/Biologist/Toxicologist

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We at AdmeScope are hiring

a Imaging Scientist /Biochemist/Biologist/Toxicologist 

with a strong experience and understanding in cell-based assays and high-throughput cell imaging techniques for one year R&D project.

You will have a key role in establishing fluorescence-based imaging methodologies for quantitative analysis of cell cultures. Your capabilities include hands-on experience in setting up the required methodologies, and preferably knowledge of high-content imaging equipment, and related analytical automation. You will design the methods together with a senior expert and be responsible for successful implementation of the methodology. If the project is successful, you have a possibility to continue in a permanent position, where your responsibilities will additionally include training our staff and contributing to the company’s services as an in vitro toxicology scientist.

You have a university degree in a suitable field (e.g. biochemistry, cell biology, toxicology), with work experience relevant to the position. Cell culture and cell imaging experience (fluorescent staining methods 2D and/or 3D) is a prerequisite. Experience in high-content imaging and ADME & toxicity in vitro/in vivo techniques are considered as a benefit.

The position will be filled in early 2023, as soon as a suitable person is identified.

We offer an interesting, versatile and challenging position in a strongly growing company with a great atmosphere, and colleagues across our global organization. Furthermore, you will have an opportunity to be part of a continuously evolving drug development landscape. The position is available at our site in Oulu, Finland.
Please send your application with salary request along with your CV, highlighting the relevant education and work experience to recruitment@admescope.com, with email subject line “Imaging Scientist”.

Technicians, manufacturing

Apply here! Hae täällä!

(see English below)

Haemme lääketehtaamme osaavaan ja kasvavaan joukkoon tuotannon operaattoreita Bufferin, Upstreamin, Downstreamin sekä Drug Productin tiimeihin.

Taustaltasi voit olla esimerkiksi laborantti, bioanalyytikko, vastavalmistunut maisteri (esim. kemia, solu- ja molekyylibiologia, biolääketiede) tai prosessiteollisuuden perustutkinnon suorittanut.

Buffer-tiimissä valmistamme kaikki tuotannossa käyttämämme liokset, Upstream-tiimissä aloitamme tuotantoprosessin soluviljelyllä ja jatkamme solujen kasvattamista bioreaktoreissa. Prosessin aikana solut infektoidaan ja lopulta kerätään talteen. Upstreamista tuote siirtyy Downstream-tiimille, joka puolestaan puhdistaa tuotteen kromatografisilla menetelmillä niin, että tuote on vihdoin valmis täytettäväksi lääkepulloihin. Drug Product -tiimi keskittyy aseptiseen täyttämiseen ja tuotteen loppuvaiheen toimenpiteisiin kuten formulointiin, fillingiin sekä pakkaamiseen liittyviin toimintoihin. Drug Product -tiimissä taustasi voi olla myös esimerkiksi farmaseutti.

Jos olet työotteeltasi tarkka ja järjestelmällinen etkä pelkää laitteita tai haasteita ja muuttuvia tilanteita, sinulla on hyvät edellytykset sopia joukkoon. Etsimme henkilöä, joka viihtyy käytännön laboratoriotyössä sekä lääketeollisuudelle tyypillisen tarkan dokumentaatiotyön parissa. Meillä on työkielenä pääasiassa englanti, joten sinun tulisi pystyä seuraaman englanninkielisiä työohjeita sekä kommunikoimaan tarvittaessa englanniksi. Ennen kaikkea etsimme kuitenkin mukavia työkavereita, joilla on can do -asenne.

Tilanteesta ja tiimistä riippuen meillä on tarjolla määräaikaisia ja toistaiseksi voimassa olevia työsuhteita ja toivoisimme sinun pystyvän aloittamaan tammikuussa tai helmikuussa. Meillä tehdään töitä 2-vuorotyönä ja osittain myös viikonloppuisin. Myöhemmin tulevaisuudessa työ voi olla myös 3-vuorotyötä.

Tarjoamme sinulle dynaamisen ja kansainvälisen työyhteisön. Tuemme fyysistä ja henkistä hyvinvointiasi hyvällä työterveyshuollon palveluvalikoimalla sekä ePassi-tilillä. Lisäksi tarjoamme sinulle kehittymismahdollisuuksia, laajan perehdytyskoulutuksen ja lämpimän vastaanoton. Ennen kaikkea pääset osalliseksi mahtavaa työporukkaa! ​FinVector sijaitsee elämää sykkivässä Kuopiossa, joka tarjoaa asukkailleen turvallisen elinympäristön, ystävällisen ilmapiirin ja puhtaan luonnon.

Hae tehtävään 18.12. mennessä oheisen hakulinkin kautta. Lisätietoja voit kysyä Senior HR Specialist Eetu Salmelalta, eetu.salmela(at)finvector.com.

_______________________________________

We are looking for a knowledgeable and growing group of Technicians to our production plant for various Manufacturing operations.

For example, you may have a background as a laboratory assistant, bioanalyst, process worker, or equipment maintainer. We have four teams in production and we are seeking new reinforcements as our operations grow rapidly. In the Buffer team, we prepare all the solutions we use in production, in the Upstream team, we start the production process with cell culture and continue by growing the cells in the bioreactors. During the process, the cells are infected and eventually harvested. From Upstream, the product is transferred to the Downstream team, which in turn purifies the product using chromatographic methods so that the product is finally ready to be filled into glass vials. Our Drug Product team focuses on aseptic filling and final stage measures e.g. formulating, filling and packaging.

You will succeed in the tasks if you are precise and systematic in your work approach and you are not afraid of equipment or challenges / changing situations. We are looking for a person who enjoys to work in hands-on laboratory work with heavy documentation that if familiar in our field of pharmaceutical manufacturing. We have English as a working language, so you must have a good command of oral and written English. Above all, however, we are looking for nice colleagues with a can-do attitude. We work in 2 shifts and partly also on weekends. In the future work may be done in 3-shifts.

Depending of the team your employment can be either fixed-term or permanent and we would like you to start in January or February. We offer you active and lively work community with highly skilled and experienced personnel in gene therapy manufacturing. Working with us, you are entitled to good staff benefits, such as extensive occupational health-care and we support your physical and cultural free-time activities. We provide you wide initial training and a warm welcome. FinVector is located in vibrant Kuopio, which offers a safe living environment, friendly atmosphere and clean nature.

We are reading applications and interviewing suitable candidates during the application period. Apply for the position by 18th December!

For more information, please contact Senior HR Specialist Eetu Salmela, eetu.salmela(at)finvector.com

Apply between 30 November 2022 and 18 December 2022 23:59 (Europe/Helsinki)

What we are looking for

• suitable educational background and professional profile
• English skills

Benefits

• physical and cultural free-time activities
• extensive occupational health-care
• ePassi wellbeing benefit

FinVector

FinVector is a fast-growing and internationally renowned biopharmaceutical company that develops and manufactures viral-based gene therapy products. As a pioneer in its operational field, FinVector has extensive experience of nearly 30 years in cGMP manufacturing. The company’s operations are centered in Kuopio, Finland, and it employs around 330 professionals from over 30 different countries. FinVector works on cutting-edge biopharmaceuticals and has invested in building state-of-the-art development and GMP facilities for Viral Vector and Cell Therapy platforms including vaccines. FinVector is owned by Ferring Ventures, a subsidiary of Ferring Foundation B.V.

Learn more: www.finvector.com

Postdoctoral Researcher, ECM & Hypoxia Research Unit, in Biocenter Oulu

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The University of Oulu is one of the largest universities in Finland, with approximately 15 000 students and 3 000 employees. We, at the University of Oulu, work as part of the international science community to produce new scientific information and science-based solutions. Our university’s several specialized research and service units enable extensive and diverse development and career opportunities for experts in various fields.

We are now looking for a full-time

Postdoctoral researcher

to join a research project headed by Professor Peppi Karppinen in the ECM & Hypoxia Research Unit, in Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine. The position is fixed time for period of 01.01.2023-31.12.2023.

Our research focuses on the enzyme family of 2-oxoglutarate-dependent dioxygenases (2OGDDs) and their potential as therapeutic targets. Our main interests are in the hypoxia-inducible factor prolyl 4-hydroxylases, P4H-TM, histone lysine demethylases (KDMs) and some understudied 2OGDDs with disease connections. We use biochemical, enzymological, cell biological and genetic mouse models to understand how these enzymes regulate normal physiological and developmental processes. In addition, we study their inhibition as a potential therapeutic option in selected pathological conditions, with main focus currently on obesity, metabolic dysfunction, aging and cancer.

More information can be found on our web page: https://www.oulu.fi/en/research-groups/prof-peppi-karppinen-nee-koivunen.

Requirements

To successfully occupy the position, you must possess a PhD degree preferably in the field of biochemistry, molecular or cell biology, medical science or related fields. Degree must have been completed before starting the position. Prior experience from recombinant protein production in different host systems, protein purification, enzyme kinetic analyses, biophysical analyses and structural biology (crystallization, cryoEM) are required. Prior knowledge of the research field is considered an advantage. Ability to pursue independent research, high motivation, good teamwork skills and excellent writing and fluency in English is expected. Good scientific presentation skills are required and teaching experience is considered an advantage.

What we offer

• A research environment with excellent technological facilities and a motivating and supporting community.
• University´s wide variety of support services, allowing you to focus on your research.
• Modern research facilities and personnel benefits such as free occupational healthcare, support for sport services and various opportunities to develop your skills and competences.
• Regular salary paid 12 months per year, including paid leave and an additional holiday bonus in the summer.
• Insurance provided by the university.
• In addition, the Finnish government provides benefits to residents and their families, for example possibility to the national healthcare system and high-quality affordable childcare and school services.

Salary

The salary will be on level 5 of the national salary scale for the teaching and research staff of Finnish universities. In addition, a supplementary remuneration is given for personal achievement and performance (max. 50 %). In practice, the salary is roughly 3720 € per month (before taxes), depending on the appointee’s qualifications and prior experience.

The position is filled for a period of 01.01.2023-31.12.2023. A six-month trial period is applied in the position.

How to apply

Applications must be submitted using the electronic application form by December 19, 2022, (23:59 Finnish local time), with the following attachments as three separate pdf files:

1. Complete CV containing contact information of at least two referees (Max. size limit of the attachment: 5 Mbytes)

2. Motivation letter (maximum 1 page) describing prior knowledge and research interests and career plans (1-2 pages; max. size limit of the attachment: 2 Mbytes).

3. Certificates/Diplomas: Scanned electronic copies of diplomas and transcripts of the records of relevant previous degrees. If the original documents are not in English, Finnish or Swedish, each document must be accompanied by an official certified translation into English or Finnish. (Max. size limit of the attachment: 2 Mbytes)

Applications sent by email will not be considered.

Other relevant information

The eligible applicants fitting best in the research profile expected for the position may be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.

Contact

Prof. Peppi Karppinen, e-mail: peppi.karppinen (at) oulu.fi

QA specialist

Apply here!

About Nanoform

Nanoform is an innovative drug particle engineering and nanotechnology company listed on the Premier-segment of Nasdaq First North Growth Market in Helsinki and Stockholm. Nanoform works together with pharma and biotech partners globally to reduce attrition in clinical trials and enhance their molecules’ formulation performance through its nanoforming services. Leveraging our in-house developed AI engine Starmap® we can also predict which customer molecules show most promise for our technology. Nanoform’s capabilities include GMP manufacturing, and its services span the small to large molecule development space with a focus on solving key issues in drug solubility and bioavailability and on enabling novel drug delivery applications.  QA Specialist

With the view of developing our organization further, we are now seeking a QA Specialist to join our Quality Assurance team. You will work together with our Production and Engineering teams to ensure Good Manufacturing Practice (GMP) compliance as we expand our facilities and increase the volume of our GMP production. You will be working on shift and will be supported by subject matter experts in the Quality Assurance, Quality Control and Research and Development teams. You will be working in our facility in Helsinki, Finland.   You will be responsible for

· Lifecycle management of Quality Management System documents, including   

• Instructions
• Master Batch Instructions and Batch Records
• Corrective and Preventive Action Plans
• Deviations
• Risk Assessments
• Change Controls
• Quality Control documents

· Developing and managing long-term archiving of Quality Management System documents 

· Participating in the development of the Quality Management System, including implementing an electronic Quality Management System 

· Embedding Quality Culture into the workplace     Ideal experience

· Bachelor’s degree from a relevant field (Pharmacy or similar field)  

· Experience in pharmaceutical Quality Assurance tasks or an interest to develop into a Quality Assurance professional 

· Excellent English both written and spoken Personal qualities we are looking for

· You thrive in a fast-paced, high-performing environment but are also comfortable with routine tasks 

· You are quality-oriented and interested in developing yourself professionally 

· You enjoy collaborating with people and working in a multi-cultural environment  What we offer to you

· A great team to join with experienced and highly motivated colleagues 

· The opportunity to utilize and develop your skills and competencies widely as we continuously create something new 

· The possibility to solve interesting challenges with experts from different functions 

· Competitive compensation package with broad employee benefits selection   

You will get to be part of a unique growth company in the pharma industry.  Interested?

To apply for this position, please supply an application letter and CV latest on18.12.2022.  

Please note that we may already start the interviewing process during the application period. Should you have any questions, please send them to Maarit Pulli, QA Manager, via email: maarit.pulli@nanoform.com   

Doctoral Researchers (PhD students) in DNA nanotechnology, molecular self-assembly, active plasmonics and artificial molecular machines

Apply here!

Molecular Nanoengineering group at the Department of Neuroscience and Biomedical Engineering, Aalto University (Finland),

is looking for motivated and talented doctoral researchers (PhD students) with an aptitude for interdisciplinary experimental research and interest in DNA nanotechnology, molecular self-assembly, active plasmonics and artificial molecular machines.

The positions are fully funded by the ERC Consolidator Grant “Electrically driven DNA-origami-based machines” (EDRIVE).

Your role and goals

You will work on design, fabrication, and characterization of electrically driven nanoscale molecular machines. As a member of the group, you will be trained in advanced methods in DNA nanotechnology (especially DNA origami), and state-of-the-art electron beam and optical microscopy and nanoscopy techniques. Depending on the background and scientific interests, your research will be directed either towards i) fabrication of active plasmonic surfaces and biosensors; or ii) construction of artificial molecular motors. We expect you to propose and develop scientific ideas and technical solutions (both individually and as part of a team), write scientific articles and contribute to teaching.  

Your experience and background

We expect the candidates to hold a MSc degree and/or have solid background at least in one of the following areas: applied physics, bionanotechnology, physical chemistry, material science, chemical engineering.  Previous experience in nanomicroscopy (AFM, TEM, SEM), DNA nanotechnology, colloidal synthesis, super resolution microscopy and nanophotonics is an advantage. Furthermore, the candidate should have good communication skills, good analytical and experimental skills and ability to work independently toward the goals of his/her project.

The position requires excellent written and spoken English.

Your team

The Molecular Nanoengineering group operates at the interface of nanoscience, DNA nanotechnology, molecular self-assembly and nanophotonics with particular focus on DNA-based self-assembled systems with functionalities tailored for biosensing, active plasmonics and nanomachinery. The group is led by Associate Professor Anton Kuzyk.

For examples of our previous research see

https://scholar.google.fi/citations?user=yL5QQkwAAAAJ&hl=en

What we offer

The expected duration of doctoral studies is four years. The initial contract is made for one year and the extension is subject to the progress of studies and research. Starting salary is approximately 2600€/month and will increase over time according to the salary system of Aalto University. The contract includes Aalto University occupational healthcare.

Department of Neuroscience and Biomedical Engineering is located at the Aalto University Otaniemi Campus which provides highly motivating multidisciplinary international research environment with excellent facilities and instrumentation.

Get to know our campus via Aalto University Virtual Tour.

Ready to apply

Apply through the link ”Apply now” at the bottom right corner of this page, and include the following items as a single pdf document in English:

• Curriculum vitae (no size limit)
• Transcript of academic records (no size limit)
• Description of research skills, experience and publications (no size limit)
• Short statement of interest and motivation (max 1 page)
• Recommendation letter(s) or names and contact details of your previous supervisors

The positions will be filled as soon as suitable candidates are identified.

More Information

Contact Prof. Anton Kuzyk (anton.kuzyk@aalto.fi) for additional information on the research topics and HR Partner Mari Kaarni on the application process (mari.kaarni@aalto.fi ). Please check the guidelines for doctoral admission at Aalto University (https://into.aalto.fi/display/endoctoralsci/How+to+apply).

Bioprocess engineer & Scientist

Täytä hakemus täällä!

Biovian on vahvasti kasvava turkulainen bioteknologiayritys. Tarjoamme sopimusvalmistusta, -analysointia ja prosessikehitystä biotekniikkayrityksille, jotka kehittävät innovatiivisia geeniterapia tai biofarmaseuttisia tuotteita. Saatamme asiakasprojekteja laboratoriosta kliiniseen potilaskäyttöön asti taidolla, innolla ja sydämellä.

Bioprocess engineer ja Scientist

Yhtiön kasvaessa haemme useampaa henkilöä tuotanto- ja laboratoriotehtäviin. Tehtävässäsi tulet keskittymään lääkeaineiden puhdistusprosesseihin, jossa työtehtäväsi on proteiinien ja geeniterapiatuotteiden puhdistuksen suunnittelu ja toteuttaminen. Puhdistusprosessit toteutetaan pääasiassa kromatografia ja suodatus (TFF) -menetelmillä.

Tehtävissä työ muodostuu yksilöllisesti osaamisalueittesi ja kokemuksesi mukaan, ja voi olla
Bioprocess engineer tehtävässä esimerkiksi:

• Osallistua lääkeainetuotannon työhön, joka tehdään kehityslaboratoriossa ja puhdastiloissa. Osassa työtehtävissä vaatimuksena on korkean aseptiikan osaaminen ja ymmärrys.
• Osallistua materiaalien siirto- ja valmisteluprosesseihin
• Osallistua laitteiden sanitointeihin, kalibrointeihin ja kvalifiointeihin.
• Tuottaa tarvittava dokumentointi prosessista yhdessä tiimin kanssa

Scientistin tehtävässä esimerkiksi:

• Osallistua lääkeainetuotannon työhön ja sen suunnitteluun, joka tehdään kehityslaboratoriossa ja/tai puhdastiloissa.
• Toimia asiantuntijana lääkeaineiden puhdistusprosesseissa
• Työhön ja projekteihin liittyvä raportointi ja dokumentointi

Job requirements

Työssä onnistuaksesi

Odotamme insinöörin tehtävään ammatillista loppututkintoa (esim. Bioalan insinööri tai vastaava) ja tutkijan tehtävään akateemista loppututkintoa (esim. biokemisti tai vastaava) tai pitkän linjan kokemusta vastaavasta työstä. Odotamme käytännön kokemusta laboratorio- ja/tai puhdastilaympäristöstä.

Toivomme sinulta kokemusta lääketeollisuudesta ja lisäksi vahvaa osaamista jollakin alla mainitusta osa-alueesta sekä asiantuntemusta useimmista niistä:

• Aseptinen työskentely
• Puhdastilatyöskentely
• Laboratoriotyöskentely
• Rekombinanttiproteiininen tai virusvektorivalmisteiden puhdistaminen ja käytännön kokemus kromatografialaitteistoista
• Kokemus GMP:stä

Olet työskentelytyyliltäsi tarkka, järjestelmällinen, reipas ja toimelias henkilö. Sinulla on myös hyvät vuorovaikutus- ja ryhmätyötaidot.

Sinulla on hyvä suomen kielen taito. Työohjeet ja dokumentointi tehdään englanniksi, joten toivomme sinulta myös hyvää englannin kielen taitoa.

Mitä sinä saat meiltä?

• Tarjoamme sinulle merkityksellisiä ja vastuullisia työtehtäviä lääkkeiden ja biologisten prosessien parissa.
• Pääset osaksi huipputiimiämme, joka koostuu monialaisista asiantuntijoista. Saat hyvän perehdytyksen tehtävään ja mahdollisuuden ammatilliseen kehittymiseen.
• Työtehtävä on kokoaikainen ja vakituinen. Työtä tehdään Turussa Kupittaalla, jossa toimipisteemme sijaitsee.
• Saat viihtyisän työpaikan, sekä hyvät henkilöstöedut – tarjoamme työntekijöillemme esimerkiksi laajan työterveyshuollon, terveysvakuutuksen sekä hyvinvointi- ja liikuntaedun.

Lisätietoja tehtävistä saat tuotantojohtaja Johanna Silvolalta (puh nro 040 350 8585). Parhaiten tavoitat Johannan 1.12.2022 klo 8:00-9:00 ja 15:00-16:00.

Kiinnostuitko?

Lähetä hakemuksesi (suomeksi tai englanniksi) palkkatoiveineen viimeistään sunnuntaihin 11.12. mennessä.

Tule mukaan työskentelemään kanssamme tulevaisuuden biologisten lääkkeiden parissa ja muuttamaan ideoita tuotteiksi!

Senior Clinical Research Associate – Parexel, Helsinki

https://www.linkedin.com/jobs/view/3343614169

About the job

Parexel is in the business of improving the world’s health. We do this by providing a suite of biopharmaceutical services that help clients across the globe transform scientific discoveries into new treatments. From clinical trials to regulatory, consulting, and market access, our therapeutic, technical, and functional ability is underpinned by a deep conviction in what we do. We believe in our values; Patients First, Quality, Respect, Empowerment & Accountability.

’Due to a growing portfolio, we are currently looking for a CRA to be based in Finland with flexible working hours.’Due to a growing portfolio, we are currently looking for a CRA to be based in Finland with flexible working hours.

Your time here

At Parexel, the CRA role offers the opportunity to go beyond the role of a typical clinical monitor. CRA’s are accountable for using their expertise to build and maintain the site relationship and ensure they’re set up for success. As the clinical sites’ sole point of contact, this includes addressing and resolving site issues and questions. You’ll also manage site quality and delivery from site identification through to close-out.As a CRA, Parexel will offer you world class technology and training catered to your individual experience. You can anticipate less travel and a lower protocol load in comparison to industry peers. Your hard work may be rewarded through a bonus incentive program, the opportunity to work within multiple therapeutic areas and an opportunity to advance your career in clinical research. If impact, flexibility, and career development appeal to you, Parexel could be your next home.

What you’ll do

• Leverage your expertise. Conduct qualification visits (QV), site initiation visits (SIV), monitoring visits (MV) and termination visits (TV) at assigned clinical sites and generate visit/contact reports.
• Build relationships. Oversee integrity of the study and utilize problem-solving skills to promote rapport with the site and staff.
• Protect patients. Review the performance of the trial at designated sites, ensure the rights and well-being of human subjects are safeguarded and are in accordance with protocol.
• Drive productivity. Develop patient recruitment strategies in conjunction with the clinical site to meet enrollment timelines, while also ensuring compliance with the approved standard operating procedures (SOPs), protocol/amendment(s), GCP, and the applicable regulatory requirement(s).
• Ensure quality. Evaluate the quality and integrity of the reported data, site efficacy and drug accountability.
• Execute. Monitor the completeness and quality of Regulatory Documentation and perform site document verification.

Job Posting Qualifications

More about you

On your first day we’ll expect you to have:

• Previous relevant work experience (preferred).
• Ability to perform clinical monitoring activities under supervision from the COL/LM.
• Bachelor’s or equivalent degree in biological science, pharmacy or other health related discipline.
• Strong interpersonal, written, and verbal communication skills within a matrixed team and bi-lingual skills would be a great asset (Swedish/Finnish)
• Experience working in a self-driven capacity, with a sense of urgency and limited oversight.
• A client-focused approach to work and flexible attitude with respect to assignments/new learning.
• The ability to manage multiple tasks, evaluate a variety of unpredictable scenarios and achieve project timelines while being able to apply your understanding of study protocol(s).
• An honest and ethical work approach to promote the development of life changing treatments for patients.
• Strong computer skills, including but not limited to the knowledge of a Clinical Trial Management System (CTMS), Electronic Document Management System (EDMS) and MS-Office products such as Excel and Word.

A little about us

Parexel is proud to be a leading Clinical Research Organization with colleagues across the globe. As a member of our team, you’ll get to know your coworkers on a personal level. Have a question? A clinical research leader, project team member, technology “super user” or collaborator are a phone call away. Our clinical research teams meet regularly to have discussions in an open environment, allowing our team members to share their expertise and promote learning within the team. Management supports and encourages career growth through consistent performance discussions and evaluations. Whether your interest is to progress into a more senior level CRA role, into line management, Quality, Project Leadership or a variety of other positions, Parexel prides itself on career opportunities for our employees.