25.9.2018 | Ajankohtaista
Postdoctoral positions in the group of Pontus Aspenström at the Department of Immunology, Genetics and Pathology at Uppsala University (www.igp.uu.se ). The Department has a broad research profile with strong research groups focused on cancer, autoimmune and genetic diseases. A fundamental idea at the department is to stimulate translational research and thereby closer interactions between medical research and health care. Research is presently conducted in the following areas: medical and clinical genetics, clinical immunology, pathology, neuro-oncology, vascular biology, radiation science and molecular tools. Department activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Akademiska Sjukhuset, Uppsala.
Work description:
Out group is studying the Ras-like family of Rho GTPases, which are key regulators of the actin filament system and thereby control vital cellular processes such as cell morphogenesis, cell polarity and cell migration. The work in our group is aimed to elucidate the Rho-dependent signalling mechanisms in health and disease. There are currently two positions on scholarships available in our group:
1. The research studies on this project will focus on the Miro GTPases, which are key players in mitochondrial homeostasis and functioning. Their importance in a physiological context also makes them significant proteins in the pathology of neurodegenerative diseases. Both proteins are linked, either directly or via downstream signalling partners, to the disease progression of Alzheimer’s and Parkinson’s diseases. The overarching aim of this project is to enhance the understanding of the function of Miro GTPases in neurodegenerative diseases.
2. The second project will focus on the role of the atypical Rho GTPases in cancer. This family of proteins are pivotal regulators of tumour cell migration and deregulated activity of Rho GTPases is often associated to poor prognosis of certain types of cancers. We are studying the role of the atypical Rho GTPases, which is a subclass of the Rho GTPases, in malignant mesothelioma and glioblastoma. The principal goal is to elucidate the mechanisms behind the derailed function of atypical Rho GTPases in cancer cell migration and metastasis.
Qualifications:
We are seeking a highly motivated, talented and well-educated researcher with a PhD degree awarded within the past three years in cell biology, neuroscience or in a related research topic.
Scholarships for carrying out postdoctoral research may be granted to persons living in other countries who come to Sweden with the intention of only staying in Sweden for all or part of their postdoctoral education. Persons who are resident in Sweden and/or have carried out all or part of their academic education at an educational institution in Sweden cannot be considered for scholarships. The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish PhD or higher.
The application should include a CV, copies of diplomas including grades, publications and a short description of your research interests.
Merits:
The applicant should have a strong background in molecular cell biology and practical experience of standard cell biology techniques, including microscopy and imaging, is a prerequisite. Uppsala University values the qualities that even gender distribution and diversity add to the research environment. We therefore welcome applicants of any gender and with different birth background, functionality and life experience.
Application:
An application must contain the following documents in English:
1. Curriculum vitae and qualifications
2. A complete list of publications.
3. A summary of current research (no more than one page).
4. Verifications for crediting of illness, military service, work for labour unions or student organisations, parental leave or similar circumstances.
5. Contact details for two reference persons.
The applications will be assessed based on eligibility requirements, achievements in related research areas, and personal suitability.
Scholarship:
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. This educational scholarship is tax-exempt.
The amount is set for twelve months at a time and is paid out on a monthly basis.
Start date: As soon as possible.
22.9.2018 | Ajankohtaista
Organisaation esittely
Lääkealan turvallisuus- ja kehittämiskeskus Fimea on sosiaali- ja terveysministeriön alainen virasto, joka valvoo ja kehittää lääkealaa väestön terveydeksi.
Tehtävän kuvaus
Erikoistutkijan pääasiallisena tehtävänä on biologisten lääkevalmisteiden laadun arviointi osana myyntilupahakemusten ja kliinisten lääketutkimusten kokonaisarviointia. Lisäksi tehtäviin sisältyy biologisiin lääkkeisiin liittyvää tieteellistä neuvontaa sekä kansallisella että EU tasolla ja toimijoiden ohjausta.
Avoinna olevaan virkaan ja vuoden mittaiseen määräaikaiseen virkasuhteeseen haetaan ensisijaisesti asiantuntijoita solubiologian ja biokemian osaamisalueilta.
Hakijalta odotamme
Tehtävien menestyksellinen hoitaminen edellyttää:
• Ylempää korkeakoulututkintoa ja tehtäväalueeseen soveltuvaa tieteellistä jatkokoulutusta tai kokemusta tieteellisestä tutkimustyöstä soveltuvilla aloilla (esim. biokemia, solubiologia, bioteknologia)
• Hyviä yhteistyö- ja vuorovaikutustaitoja
• Kykyä ja halua kotimaiseen ja EU-yhteistyöhön moniammatillisessa asiantuntijaorganisaatiossa
• Sujuva suomen- ja englannin kielen suullista ja kirjallista taitoa sekä tyydyttävää ruotsin kielen taitoa
Hakijalle katsotaan eduksi:
• Erityisosaaminen solubiologian alalta tai laaja-alainen asiantuntemus biokemian alueelta
• Kokemus soluvalmisteiden tai rekombinanttiproteiinien lääkekehityksestä ja/tai lääketuotannosta
• Käytännön kokemus rekombinanttiproteiinien karakterisointi-tutkimuksista sekä analyysimenetelmien validointitutkimuksista.
Työssä tarvittava kielitaito
Sujuva suomen- ja englannin kielen suullinen ja kirjallinen taito sekä tyydyttävä ruotsin kielen taito.
Tehtävän tiedot
Tehtävän kesto: Vakinainen
Työaika: Virastotyöaika
Tehtävä alkaa: 1.11.2018 Tai sopimuksen mukaan.
Virka on viraston yhteinen.
Tehtävän hakemista koskevat tiedot
Hae viimeistään: 28.9.2018 16:15
ID: 33-263-2018
Voit kuitenkin hakea tätä työpaikkaa myös toimittamalla hakemuksesi alla olevaan osoitteeseen. Sekä hakemuksessa että kirjekuoressa tulee mainita haettavan tehtävän ID. Hakemuksia ei palauteta.
Lääkealan turvallisuus- ja kehittämiskeskus/Kirjaamo
PL 55
00034 FIMEA
Palkkaukseen liittyvät tiedot
LAP –prosessin FBY-yksikön erikoistutkijan virka on sijoitettu vaativuusluokkaan 11a, jossa tehtäväkohtainen palkanosa on 4444,96 euroa/kk. Virassa maksetaan lisäksi henkilökohtaiseen työsuoritukseen perustuvaa palkanosaa, joka on enintään 42 % tehtävän mukaisesta palkasta.
Tehtävä
Ilmoitettujen työpaikkojen määrä: 2
vakituinen virka ja määräaikainen virkasuhde
Yhteystiedot
Lisätietoja tehtävästä
Niklas Ekman Jaostopäällikkö +358 29 522 3321
Marjo-Riitta Helle Yksikönpäällikkö +358 29 522 3320
Muut tehtävään liittyvät tiedot
Fimea toimii monipaikkaisena virastona. Fimean toimipaikat ovat Kuopiossa, Helsingissä, Tampereella ja Turussa. Viran sijoituspaikka voidaan sopia.
21.9.2018 | Ajankohtaista
Postdoctoral researcher in Molecular Systems Immunology and Computational Biomedicine Group at Turku Centre for Biotechnology
A position for a postdoctoral researcher working in Elo and Lahesmaa Laboratories is open for applications. We are looking for a highly motivated scientist in bioinformatics who is interested in Molecular Systems Immunology, T cell epigenomics and molecular mechanisms of immune mediated diseases. Successful applicant will join our international research groups at Turku Centre for Biotechnology, BioCity Turku, Turku, Finland and will be co-supervised by Dr. Laura Elo, Research Director in Bioinformatics and Dr. Riitta Lahesmaa, Academy professor, at Turku Centre for Biotechnology, University of Turku, Finland.
Description of recruiting organization
Turku Centre for Biotechnology (www.btk.fi) is a joint department of University of Turku (www.utu.fi) and Åbo Akademi University, providing high-end technologies and expertise to academic and industrial researchers and a stimulating multidisciplinary and international research environment. Successful applicant will
The Medical Bioinformatics Centre and the Computational Biomedicine Group of Research Director Laura Elo (http://elolab.utu.fi/ ) develops computational data analysis tools and mathematical models for biomedical research, with the eventual goal of improving the diagnosis, prognosis and treatment of complex diseases, such as diabetes, cardiovascular diseases and cancer. A specific focus is on analysing and interpreting data generated by modern high-throughput biotechnologies, such as deep sequencing and mass-spectrometry proteomics.
Molecular Systems Immunology group (http://www.btk.fi/research/research-groups/lahesmaa/ ) aims at understanding the regulation of human immune system to predict, prevent and treat immune mediated disorders. We study epigenetic and transcriptional regulation of T cells and molecular mechanisms of immune mediated diseases such as Type 1 Diabetes.
Description of the position to fill
The postdoctoral researcher will work on projects aiming at regulation of immune response in health and immune mediated disorders. These include detection of biomarkers for immune mediated diseases as well as unraveling the underlying molecular mechanisms. She/he will join our multidisciplinary team with backgrounds in mathematics, statistics, computer science, bioinformatics, biology and medicine.
The work of the postdoctoral researcher involves development and application of computational and statistical methods for the analysis of high-throughput molecular data, with a focus on next generation sequencing data and their combination with other omics data.
The position is for 2 years. Starting date is 1.11.2018 and is negotiable. The salary is in accordance with the universities salary system (for teaching and research personnel) level 5-6 where the work specific salary component is 2893,95 – 3374,18 €/month. In addition, there is a share increase based on personal performance, which is at most 46.3% of the base salary. There is a trial period of six months.
Qualifications
Successful applicants have:
– A relevant Doctoral degree (e.g. bioinformatics, computational biology, biostatistics)
– Scientific publications in high impact international journals
– Previous experience in next generation sequencing, epigenomic and genomic research and related analysis platforms and tools
– Experience in R, Matlab or other mathematical/statistical software
– High level of motivation, self-initiative and independency
– Excellent team work and communication skills in English (both oral and written)
– Previous experience in immunology is considered an advantage
– International research experience and experience in supervision of students is considered an advantage
Application
The applications for the position should be submitted latest on 30.09.2018 using the electronic system. The application should include a motivation letter, CV, list of publications, contact information for 3 referees, and copies of relevant degree certificates. A link to the electronic application system can be found on top of the position advertisement from the following link: www.utu.fi/careers .
For further information on the positions please contact: Prof. Riitta Lahesmaa, e-mail: riitta.lahesmaa@utu.fi . Enquiries on the application procedure may be directed to HR specialist Paula Luoma, paula.luoma@utu.fi .
This is an interesting and developing position in a rapidly growing area of science – so we encourage you to send your application as soon as possible. We will interview suitable candidates already during the application process. We welcome you cordially to our multicultural working community.
21.9.2018 | Ajankohtaista
Postdoctoral researcher or project researcher to study immunoregulation in Molecular Systems Immunology Group at Turku Centre for Biotechnology
Our international multidisciplinary research group (https://www.btk.fi/research/molecular-systems-immunology/) led by Academy Professor Riitta Lahesmaa is based at Turku Centre for Biotechnology (the Centre), BioCity Turku, Turku, Finland. We are seeking for a motivated postdoctoral researcher or project researcher with possibility to continue work as a doctoral candidate.
Disorders in immune system and lymphocyte function lead to inflammatory diseases e.g. rheumatoid arthritis and Type 1 Diabetes. Project will focus on studying the molecular mechanisms underlying immune mediated diseases aiming at enabling individualized treatment in the future.
Description of recruiting organization
Molecular Systems Immunology group aims at understanding the regulation of human immune system to predict, prevent and treat immune mediated disorders. We study epigenetic and transcriptional regulation of T cells and molecular mechanisms of immune mediated diseases such as Type 1 Diabetes.
Turku Centre for Biotechnology is a joint research institute of University of Turku and Åbo Akademi University. The mission of the Centre is to promote high quality research and training. The Centre has excellent state-of-the-art technology platforms and expertise in NGS, epigenomics, proteomics, computational biology and high-end cell imaging.
Qualifications
Successful candidates have:
- A relevant doctor’s degree (postdoctoral researcher) or a relevant master’s degree (project researcher) e.g. in life sciences or in biomedicine
- High level of motivation, self-initiative and independency
- Excellent team work and communication skills in English (both oral and written)
- First-rate molecular and cell biology knowledge and skills with a strong background in epigenetics.
- Strong publication record in international journals (postdoctoral researcher) at least in one of the following areas: immunology, molecular and cellular biology, autoimmunity, genetics, epigenetics.
Application
The salary is in accordance with the University salary system (for teaching and research personnel) level 5 (postdoctoral researcher) where the work specific salary component is 2 893,95 €/month or levels 3-4 (project researcher), where the work specific salary component is 2203,25 2500,06 €/month. In addition, there is a share increase based on the personal performance, which is, at most, 46.3% of the base salary. The position starts at earliest on Nov 1st, 2018 (or as agreed). The positions are initially for two years, one optional year possible. There is a trial period of six months.
The deadline for applications is Sept 30th, 2018 (23:59). A link to the electronic application system can be found from the following link: www.utu.fi/careers . Please include a CV, full publication list, list of selected publications and contact information for three references in your application.
For further information on the positions please contact: Prof. Riitta Lahesmaa, e-mail: riitta.lahesmaa@utu.fi . Enquiries on the application procedure may be directed to HR specialist Paula Luoma, paula.luoma@utu.fi .
19.9.2018 | Ajankohtaista
Etsitään solubiologiasta kiinnostunutta gradutyöntekijää ja/tai harjoittelijaa tutkimusprojektiin, jonka aiheena on HDL:n vaikutus soluhengitykseen. Projekti toteutetaan yhteistyössä prof. Heikki Kainulaisen (Jyväskylän yliopisto, Liikuntabiologia) ja tutkimusjohtaja Matti Jauhiaisen (Lääketieteellinen tutkimuslaitos Minerva, Helsinki) tutkimusryhmien kanssa ja työt tehdään Jyväskylän yliopiston liikunta- ja terveyslaboratoriossa (jäähallin ja hipposhallin välissä Hippoksella).
Projektissa pääsee tutustumaan mm. soluviljelymenetelmiin HDL:n eristykseen verinäytteestä ultrasentrifugaatiolla sekä käsiteltyjen solujen analysointiin esim. niiden soluhengitystä mittaamalla (high resolution respirometry).
Päävastuu työsi ohjauksesta on allekirjoittaneella, mutta myös muilta laboratoriossa työskenteleviltä tutkijoilta saat apua ja ohjausta. Projektin avulla saat käsityksen työskentelystä useamman projektin yhteisessä laboratoriossa, kokemusta useasta biotieteiden alalla käytössä olevasta tutkimusmenetelmästä ja käytännön kokemuksen tieteenteosta.
Sinulta odotetaan laboratoriossa työskentelyn perustaitoja, soluviljelykurssilla opittavia taitoja ja kykyä itsenäiseen työskentelyyn.
Projektin voi aloittaa jo syksyllä, mutta kokeellinen osa toteutuu pääosin kevään aikana.
Mikäli kiinnostuit, ota yhteyttä.
Maarit Lehti, FT
LIKES-tutkimuskeskus
Rautpohjankatu 8
40700 Jyväskylä
maarit.lehti@likes.fi
040 550 3515
18.9.2018 | Ajankohtaista
Tällä kertaa Suomen Solubiologit ry:n Instagramin kaappaa Johanna Matilainen, joka toimii yhdistyksen tiedotussihteerinä ja nuorempana tutkijana (Eli väitöskirjatyöntekijänä) Kuopion biolääketieteen yksikössä Itä-Suomen yliopistossa. Tervetuloa seuraamaan jatko-opiskelijan arkea @SuomenSolubiologit tilillämme!
17.9.2018 | Ajankohtaista
The research group “Host-Pathogen-Microbiota Interaction” (HOPI) of Jun. Prof. Alexander J. Westermann at the Helmholtz Institute for RNA-based infection research (HIRI) in Würzburg (Germany) is offering a PhD position “Bacterial RNA biology in the gut microbiota”
The Helmholtz Institute for RNA-based Infection Research (HIRI) has been established in May 2017 as joint venture between the Helmholtz Centre for Infection Research (HZI) and the Julius Maximilian University of Würzburg (JMU). Located on the Würzburg medical campus, it is the first research institution worldwide to exclusively address the role of ribonucleic acids (RNAs) in infection processes. Based on these findings, the HIRI will pioneer an integrative approach to exploit the vast potential of RNAs as a diagnostic molecule, target and drug for new strategies to combat infectious diseases. For further information, please visit: www.helmholtz-hiri.de or www.helmholtz-hzi.de/hiri.
Project description:
The HIRI is recruiting a doctoral student to identify and characterize noncoding RNAs and RNA-binding proteins (RBPs) in anaerobic bacterial members of the mammalian gut microbiota. The project will rely on microbiological and cell-culture techniques, CRISPR interference screening, RNA-seq approaches, and the mechanistic characterization of the resulting RNA and RBP candidates using bacterial genetics and a variety of biochemical approaches. More information on current research themes in the research group can be found as part of Jun. Prof. Westermann’s profile on the HZI website.
Further reading:
• Westermann et al. (2016) Nature 529:496-501
• Westermann & Barquist et al. (2017) Plos Pathog 13(2):e1006033
• Hör, Gorski, Vogel (2018) Mol Cell S1097-2765(17)30980-2
Qualifications:
• Master’s Degree/Diploma in molecular biology, microbiology, immunology, biotechnology, bioinformatics or a related field
• Basic practical molecular biological, biochemical and/or microbiological skills
• Previous experience in infection biology, bacteriology or RNA biology
• Strong written and spoken English language communication skills
• Ability to work independently and as part of an international team
• A strong desire to do research, enthusiastic, creative and highly self-motivated
Desired (non-essential) background:
• Previous experience working with large-scale biological data sets, particularly RNA-seq and/or CRISPRi data
• Familiarity with the microbiome
• Knowledge of a scripting language (Python, Perl, etc.) and R
Equally well-qualified disabled applicants will be given preference. The HIRI expressly invites women to apply.
Starting date: November 15, 2018 – Initial term 1 year, with the possibility of an extension of additional 2 years –
Place of work: Helmholtz Institute for RNA-based Infection Research (HIRI)
Josef-Schneider-Straße 2, 97080 Würzburg, Germany
Salary: TVöD E13 (50%) with the possibility of an additional payment of 10%
Probation period: 6 months
Published: September 11, 2018
Closing date: October 14, 2018
Application: Applicants are required to complete the online application form here:
17.9.2018 | Ajankohtaista
PhD thesis position with a possibility to start with MSc (Pro Gradu) project is available in the research group led by Academy of Finland Research Fellow Dr. Saara Ollila. The project focuses in the functional and molecular interactions between gastrointestinal epithelial, stromal and neuronal cells during homeostasis and in carcinogenesis. The model systems and methods include cell and primary organoid culture as well as in vivo models and molecular biology methods.
The group belongs to the Translational Cancer Biology Program in the Research Programs Unit of the Faculty of Medicine in University of Helsinki. This strong and established cancer research environment provides an excellent opportunity for interactions with top level national and international researchers and clinicians.
We offer a position in a young, active and teamwork-oriented group in an excellent research environment. We are looking for a motivated student of molecular biology, biochemistry, genetics, physiology, or related. Advantageous areas of interests and experience include molecular biology, cell culture, mouse models, bioinformatics and image analysis.
To apply, please send a CV including a short cover letter and names and contact details of at least two referees as one single document to saara.ollila(at)helsinki.fi. Applications will be accepted until the position is filled. Email for more information!
17.9.2018 | Ajankohtaista
The Department of Cell Biology and Neuroscience (CBN), Rutgers University, invites applications for a tenure-track faculty position at the Assistant Professor level to develop an innovative and interdisciplinary research program in neuroscience.
CBN is home to a collegial faculty with diverse interests encompassing neurobiology, physiology, molecular biology, stem cell biology, and immunology. Ample opportunities for collaboration exist within the Department, the broader Division of Life Sciences, nearby Rutgers Institutes such as The Brain Health Institute, The Institute for Quantitative Biomedicine, The Cancer Institute of New Jersey, The Child Health Institute, and The Robert Wood Johnson Medical School. Rutgers provides excellent facilities and competitive start-up packages.
Applicants must hold a Ph.D., MD or equivalent degree, have at least 4 years of postdoctoral training in neuroscience, and a strong record of scholarly achievement. Priority will be given to outstanding applicants whose research focuses on neurophysiological analysis of single cells and circuits in the mammalian brain. The successful candidate will be expected to contribute to the teaching of undergraduate and graduate level courses in her/his field of expertise, and maintain a productive extramurally funded research program.
Interested individuals are encouraged to apply online by submitting a curriculum vitae, a brief statement of research plans, and the contact information of three individuals who will provide letters of reference.
Applications should be submitted as soon as possible but not later than December 31, 2018. Late applications may be considered until the position is filled.
Rutgers University is an equal opportunity/affirmative action employer.
17.9.2018 | Ajankohtaista
A postdoctoral position is available in the newly established laboratory of Adj.prof. Leena Latonen in University of Eastern Finland, School of Medicine, Institute of Biomedicine, Kuopio Campus. Our laboratory studies cancer-associated cellular mechanisms against protein and RNA toxicity.
We are seeking for a motivated Postdoctoral Researcher to join the Academy of Finland funded project studying epithelial functions of androgen receptor-linked RNA binding proteins. We are interested in understanding the roles in cellular stress responses of macromolecules aberrated in prostate cancer. We use modern cell and molecular biology techniques ranging from imaging to next generation sequencing. In this project, we focus on interactions between protein and RNA molecules as well as intracellular traffic of macromolecular complexes.
A person to be appointed as a postdoctoral researcher shall hold a suitable doctoral degree (e.g. molecular or cell biology, or alike), a publication record of high quality, fluent written and spoken English, and ability to work both independently as well as a part of a group. Previous experience in RNA biology, mammalian cell culture and/or cellular imaging will be an asset.
The Postdoctoral Researcher position is filled initially for two years starting from 1.11.2018 (or negotiated).
The deadline for the postdoc applications is 30.9.2018.
The laboratory is also inviting applications for Ph.D. students. For this, send your expression of interest and CV to leena.latonen@uef.fi .
