Ajankohtaista

Postdoctoral Researcher or Early Stage Researcher (PhD student), evolutionary biology, reproductive physiology and molecular biology – University of Eastern Finland

The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,000 students and 2,500 members of staff. We operate on two campuses in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.

The Faculty of Science and Forestry operates on the Kuopio and Joensuu campuses of the University of Eastern Finland. The mission of the faculty is to carry out internationally recognised scientific research and to offer research-education in the fields of natural sciences and forest sciences. The faculty invests in all of the strategic research areas of the university. The faculty’s environments for research and learning are international, modern and multidisciplinary.  The faculty has approximately 3,800 Bachelor’s and Master’s degree students and some 490 postgraduate students. The number of staff amounts to 560. http://www.uef.fi/en/lumet/etusivu

We are now inviting applications for a Postdoctoral Researcher or an Early Stage Researcher (PhD student) (evolutionary biology, reproductive physiology and molecular biology) position, Department of Environmental and Biological Sciences, Joensuu and/or Kuopio Campus

The application needs to be submitted no later than 30.4.2019 (by 24.00 hours Finnish time).

More information and application at http://www.uef.fi/en/uef/en-open-positions

PhD student position in Synthetic Biology for Improved Cell Factories – University of Oulu

https://www.linkedin.com/jobs/view/1181083988/?recommendedFlavor=HIDDEN_GEM&refId=d6325664-887e-4a81-9ff2-1945f6c9e4eb&trk=eml-jymbii-organic-job-card&midToken=AQFgumZyIt6sOQ&trkEmail=eml-jobs_jymbii_digest-null-3-null-null-41f64x%7Ejtkiqwnk%7Em9-null-jobs%7Eview

PhD student position in Synthetic Biology for Improved Cell Factories

The SECRETERS Marie Sklodowska Curie Innovative Training Network aims to develop “ A new generation of microbial expression hosts and tools for the production of biotherapeutics and high-value enzymes ”. The project will involve extensive collaborations between 6 academic and 5 industrial participants, who are based in 6 European countries.

The SECRETERS partnership aims to bring about a step change in the production of recombinant proteins, particularly Biotherapeutics and Industrial Enzymes. Both are critical products for the EU biotechnology sector, with combined markets in excess of $140 billion p.a.; the former are essential for the treatment of major diseases whereas the latter permeate every aspect of our daily life. Many proteins in these categories pose severe problems in production, especially disulfide-bonded proteins and new format ’difficult-to-express’ proteins. SECRETERS will train a team of 15 early stage researchers (ESRs) to develop a new generation of super-producing microbial production hosts, including Escherichia coli , Bacillus species and the yeast Pichia pastoris . The project capitalizes on a series of recent innovations and involves close collaboration between 6 academic Beneficiaries, who provide world-leading expertise in redox chemistry, synthetic biology and protein expression, and 5 non-academic Beneficiaries, who include some of the world’s premier biotherapeutic and industrial enzyme companies. It will enable the biotherapeutics industry to produce challenging medicines at lower costs, resulting in new drugs and wider patient access, and allow the enzymes industry to deliver a range of powerful new products. Based on a responsible innovation approach, with clear foci on research and entrepreneurial training, SECRETERS will deliver a team of superbly-trained scientists, poised to engage in some of Europe’s most important biotechnology sectors.

We Offer

An open PhD student position is available in the field of synthetic biology for improved cell factories in the research group of Prof Lloyd Ruddock (http://www.oulu.fi/biocenter/groups/ruddock). The appointed PhD student will work within the SECRETERS ITN on developing improved systems for catalyzed disulfide bond formation in the cytoplasm of E.coli .

The University of Oulu in Northern Finland, is an international, multidisciplinary research university with a rich pool of creative and intellectual talent. The strengths of the University include broad, multidisciplinary research interests, a modern research and study environment, and wide cooperation with international research and educational institutes (

The position is located at the Faculty of Biochemistry and Molecular Medicine (FBMM) (

Description Of The Project

The project is aimed at the development of new ways to produce disulfide-bonded proteins in the E.coli cytoplasm using CyDisCo technology. 2 nd generation CyDisCo components will be developed to improve on the already high levels of target protein production, with a special focus on the generation of high yields of complex proteins with large numbers of disulfide bonds. Quantitative data on expression levels of disulfide-bonded proteins in E.coli will be generated for modelling by other ESRs in the consortium.

The ESR will participate in an extensive training programme, including secondments to industrial partners in the consortium.

The position is a fixed MCA actions ESR fellowship. This position is for 36 months . The salary will be around 3000 €/month, depending on experience. According to the ITN rules a mobility allowance and, if eligible, family allowance are included. The starting date is Sept 1, 2019, or as soon as possible thereafter.

A six-month trial period will be effective in the beginning of a contract.

Required Qualifications And Assessment

Excellent applicants with degrees and/or expertise in biochemistry, biotechnology, molecular biology or systems biology are invited. The successful applicant must hold a MSc degree in one of these fields. Candidates who have completed required courses and whose MSc thesis will be submitted by May 1 st 2019 will also be eligible.

The applicant must fulfill the criteria for admission to UniOGS:

Fluent oral and written English skills as well as good communication and teamwork skills are required.

At the date of recruitment, applicants must be in the first four years of their career and not have a doctoral degree. They can be a national of any country, but must not have resided or carried out main activity (studies, work etc) in Finland for more than12 months in the 3 years immediately prior to the recruitment date.

Application Procedure

The following documents must be attached to the application (in English):

• Curriculum vitae with the names and contact details of at least 2 referees
• Brief description of research merits, experience and motivation
• Copies of the MSc certificate and transcript
  
  

Applications, together with all relevant enclosures, must be submitted using the electronic application system by 30.3.2019 (link via

Selected candidates will initially be invited for an interview by Skype. Short-listed candidates will then be invited for a recruitment symposium in May 2019 in Groningen, the Netherlands, for which travel costs and accommodation will be reimbursed.

For Further Information Regarding The Filling Of This Post

Prof Lloyd Ruddock, group leader, email: lloyd.ruddock(at)oulu.fi

Tiina Hurskainen, HR manager, email: tiina.hurskainen(at)oulu.fi

Postdoctoral Researcher, Bioinformatics, Toxicogenomics and Machine Learning – University of Eastern Finland, Institute of Biomedicine

https://rekry.saima.fi/certiahome/open_job_view.html?id=00007118&did=5600&lang=en&jc=16&nav_from_open_jobs_view_new=true

The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 2 500 degree students and about 450 PhD students in the Faculty. The faculty has 680 staff members. http://www.uef.fi/en/ttdk/etusivu
We are now inviting applications for

a Postdoctoral Researcher (Bioinformatics, Toxicogenomics and Machine Learning) position, School of Medicine, Institute of Biomedicine, Kuopio Campus.

The position is available in the Biomedical Informatics research group (http://www.uef.fi/web/biomedicine/biomedicalinformatics) led by Dr Vittorio Fortino, in the recently launched EU H2020 project EDCMET.

The project is focused on the development of computational methods to identify endocrine disrupting effects of chemicals. This work will employ bioinformatics and cheminformatics methodologies, toxicology and toxicogenomic databases, data mining and machine learning to; (a) predict the overall biological phenotype emerging from a chemical exposure (e.g. adaptive versus adverse); and, (b) to identify suitable biomarkers for chemical exposure and effect.

The ideal candidate will have a strong background in omics data analysis, with experience in data mining and machine learning methods applied to toxicogenomics and/or toxicology data. She or he will have an inquisitive mindset, a proactive attitude and the desire to work in a multi-disciplinary team. She or he will join a vibrant scientific community and collaborate with other scientists across disciplines, including molecular biology, systems biology, data science and translational medicine.

A person to be appointed as a postdoctoral researcher shall hold a suitable doctoral degree. Positions of postdoctoral researchers shall always be filled for a fixed term (UEF University Regulations, Section 31).

The person to be appointed to the Postdoctoral Researcher Position is required to hold a doctoral degree, which may not have been completed more than five years ago at the time of accepting the position. In this context, the 5 years refer to a net period of time, which does not include maternity leaves, parental leaves, or military service, etc.

The language requirements associated with the position are defined in the Government Decree 770/2009. Members of the university’s teaching and research staff are required to have command of the language they give teaching in (Finnish or Swedish). The Dean of the faculty may grant an exemption from the language proficiency requirements laid down in the Government Decree.

Other qualification requirements/ prerequisites

• A strong track record in omics data analysis (e.g. genome-wide, rna-seq and proteomics data analysis).
• Proficient in programming in R or Python, basic knowledge of statistical modelling and data mining, and ability to query databases and handle large data sets.
• Experience in using toxicology and toxicogenomic databases is a plus.
• Excellent analytical, communication and organizational skills.
• Demonstrated capability as highly organized, a creative problem-solver, self-motivated and able to work independently as well as within cross-functional teams. 
• Fluency in written and spoken English

The position is initially filled for a fixed-term of three years. The full-time position will start in June 2019, or later by agreement.
The salary of the position is determined in accordance with the salary system of Finnish universities and is based on level 5 of the job requirement level chart for teaching and research staff (€2,935,55/ month). In addition to the job requirement component, the salary includes a personal performance component, which may be a maximum of 50 % of the job requirement component.

For further information on the position, please contact: Assistant Professor Vittorio Fortino, email: vittorio.fortino@uef.fi, phone +358 29 4454197. For further information on the application procedure, please contact HR Secretary Tellervo Rajanto, email: tellervo.rajanto@uef.fi, phone +358 29 4454278.  

A probationary period is applied to all new members of the staff.

The electronic application should contain the following appendices:
– a résumé or CV
– a list of publications
– motivation letter
– copies of the applicant’s academic degree certificates/ diplomas, and copies of certificates / diplomas relating to the applicant’s language proficiency, if not indicated in the academic degree certificates/diplomas 

The application needs to be submitted no later than 8.4.2019 (by 24.00 hours Finnish time) by using the electronic application form.

Early Stage Researcher, Bioinformatics /Omics Data Analytics and Machine Learning) position – University of Eastern Finland, Institute of Biomedicine

https://rekry.saima.fi/certiahome/application_edit_welcome.html?field_id=0&job_name=Early+Stage+Researcher%2C+Bioinformatics+%2FOmics+Data+Analytics+and+Machine+Learning%29+position&job_id=7081&jc=16&lang=en&place_id=187&did=5600

The University of Eastern Finland, UEF, is one of the largest multidisciplinary universities in Finland. We offer education in nearly one hundred major subjects, and are home to approximately 15,500 students and 2,500 members of staff. We operate in Joensuu and Kuopio. In international rankings, we are ranked among the leading universities in the world.

The Faculty of Health Sciences operates at the Kuopio Campus of the University of Eastern Finland. The Faculty offers education in medicine, dentistry, nutrition and pharmacy, as well as in some other central fields of the health care sector. The Faculty is research-intensive, and its internationally recognised research activities are closely linked to the strategic research areas of the University. There are approximately 2 500 degree students and about 450 PhD students in the Faculty. The faculty has 680 staff members. http://www.uef.fi/en/ttdk/etusivu

We are now inviting applications for

an Early Stage Researcher (Bioinformatics / Omics Data Analytics and Machine Learning) position, School of Medicine, Institute of Biomedicine, Kuopio Campus

The position is available in the Biomedical Informatics research group (http://www.uef.fi/web/biomedicine/biomedicalinformatics) led by Dr Vittorio Fortino, in the recently launched EU H2020 project BIOMAP.

The project is focused on the analysis of multi-omics data for identifying and targeting personalized treatments in two common chronic skin diseases: atopic dermatitis (AD) and psoriasis (Pso). The aim of the project is to develop novel computational methods and tools for multi-omics data modelling and the definition of disease subtypes and predictive biomarkers. The topics of the research projects will be discussed in more detail during the interview of the selected candidates.

A person to be appointed as an early stage researcher shall be qualified to pursue postgraduate studies, i.e. he or she is required to have completed a suitable higher university degree or an equivalent education abroad which in the country in question would qualify the person for similar academic studies. Positions of early stage researchers shall always be filled for a fixed term (UEF University Regulations, Section 31).

Good command of the English language is required. The language requirements associated with the position are defined in the Government Decree 770/2009. Members of the university’s teaching and research staff are required to have command of the language they give teaching in (Finnish or Swedish). The Dean of the faculty may grant an exemption from the language proficiency requirements laid down in the Government Decree.

Applicants with a background in molecular biology and bioinformatics analysis of next-generation sequencing and microarray data are encouraged to apply. Persons graduating in the near future are also encouraged to apply. However, they are expected to hold a relevant MSc degree (or equivalent) by the starting date of the early stage researcher position. A successful candidate will have good command of the English language and good skills in data analysis and programming, specifically experience in R/Python and Linux is highly desired.

The position is initially filled for a fixed-term of two years. The full-time position will start in May 2019, or later by agreement.

The salary of the position is determined in accordance with the salary system of Finnish universities and is based on levels 2-4 of the job requirement level chart for teaching and research staff (€2,033,29 – 2,535,20/month). In addition to the job requirement component, the salary includes a personal performance component, which may be a maximum of 50 % of the job requirement component.

For further information on the position, please contact: Dr Vittorio Fortino, email: vittorio.fortino@uef.fi, phone +358 29 4454197. For further information on the application procedure, please contact HR Secretary Tellervo Rajanto, email: tellervo.rajanto@uef.fi, phone +358 29 4454278.  
A probationary period is applied to all new members of the staff.

The electronic application should contain the following appendices:
– a résumé or CV
– a list of publications
– motivation letter
– copies of the applicant’s academic degree certificates/ diplomas, and copies of certificates / diplomas relating to the applicant’s language proficiency, if not indicated in the academic degree certificates/diplomas

The application needs to be submitted no later than 1.4.2019 (by 24.00 hours Finnish time) by using the electronic application form.

Tutkijatohtori/nuorempi tutkija (evoluutiobiologia, lisääntymisfysiologia ja molekyylibiologia) – Itä-Suomen yliopisto, Ympäristö- ja Biotieteiden laitos

https://rekry.saima.fi/certiahome/open_job_view.html?id=00007129&did=5600&lang=fi&jc=16&nav_from_open_jobs_view_new=true

Itä-Suomen yliopisto on yksi Suomen suurimmista monialaisista tiedeyliopistoista. Tarjoamme opetusta lähes sadassa pääaineessa. Opiskelijoita on noin 15 000 ja työllistämme 2 500 henkilöä. Toimimme kahdella kampuksella Joensuussa ja Kuopiossa. Kansainvälisissä yliopistojen vertailuissa sijoitumme maailman parhaiden joukkoon.

Luonnontieteiden ja metsätieteiden tiedekunta toimii Itä-Suomen yliopiston Kuopion ja Joensuun kampuksilla. Tiedekunnan tehtävänä on harjoittaa korkeatasoista kansainvälistä tieteellistä tutkimusta ja tarjota siihen perustuvaa yliopistollista koulutusta luonnontieteiden ja metsätieteiden alalla. Tiedekunta panostaa yliopiston strategian mukaisiin tutkimusalueisiin. Tiedekunnan tutkimus- ja oppimisympäristöt ovat kansainvälisiä, moderneja ja monitieteisiä. Tiedekunnassa on noin 3 800 perustutkinto-opiskelijaa ja 490 jatko-opiskelijaa. Henkilöstömäärä on noin 560. http://www.uef.fi/fi/lumet/

Haettavana on

Tutkijatohtorin tai nuoremman tutkijan (evoluutiobiologia, lisääntymisfysiologia ja molekyylibiologia) tehtävä, Ympäristö- ja Biotieteiden laitos (Joensuun ja/tai Kuopion kampus)

Haemme motivoitunutta määräaikaista tutkijatohtoria/nuorempaa tutkijaa (jatko-opiskelijaa) Suomen Akatemian rahoittamaan hankkeeseen ”Ihmisen sukusolujen yhteensopivuuden molekulaarinen ja immunologinen perusta”, https://reprophys.weebly.com/ Hankkeen tavoitteena on selventää naisen lisääntymiselimistössä tapahtuvan siittiöiden valinnan (’cryptic female choice’), hedelmöittymisen sekä hedelmättömyyden molekyylibiologisia ja immunologisia mekanismeja. Vaikka hedelmöittymisen mekanismeja on tutkittu jo yli 100 vuoden ajan, hedelmöittymisprosessi on edelleen yksi heikoimmin tunnetuista biologisista tapahtumista. Tämä rajoittaa paitsi lisääntymisen ja lisääntymisongelmien, myös evoluution ja perinnöllisyyden mekanismien ymmärtämistä.

Palkattavan tutkijan tehtävänä on osallistua näitä mekanismeja havainnollistavaan kokeelliseen tutkimukseen ihmisellä. Riippuen valittavan henkilön kokemuksesta, työtehtäviin voi kuulua mm. molekyylibiologiset (mm. uuden sukupolven sekvensointi) ja immunogeneettiset (mm. Human Leucocyte Antigen) analyysit, siittiöiden liikkuvuus- ja kemotaksiatutkimukset sekä naisen lisääntymiselimistön ja erilaisten ympäristöaltisteiden indusoimien siittiöiden fysiologisten muutosten mittaaminen. Erityisesti toivomme hakemuksia uuden sukupolven sekvensointiaineiston bioinformaattisten analyysien osaajilta. Työtehtäviin kuuluu myös kerätyn aineiston analysointi ja raportointi tieteellisissä julkaisusarjoissa.

Hakijalta edellytetään hyvää englannin kielen kirjallista ja suullista taitoa. Aiempi kokemus laboratoriotyöskentelystä, molekyylibiologisista (esim. RNA-seq analyysit ja bioinformatiikka) ja/tai solubiologista (esim. virtaussytometria ja ELISA analyysit) menetelmistä katsotaan eduksi hakijalle. Jos sinulla on jokin näistä taidoista, pyydämme kertomaan siitä ansioluettelossa ja/tai motivaatiokirjeessä (ks. alla).

Tutkijatohtorilta edellytetään soveltuva tohtorin tutkinto, joka on suoritettu enintään 5 vuotta ennen tutkijatohtorin tehtävän vastaanottamista. Mikäli tohtorin tutkinto on suoritettu yli 5 vuotta ennen tehtävän aloittamista, hänet otetaan projektitutkijan tehtävään. Aikaraja tarkoittaa tässä yhteydessä nettoaikaa, johon ei lasketa esim. äitiys- tai vanhempainlomaa tai asevelvollisuuden suorittamista.

Projektissa on mahdollisuus tehdä myös väitöskirjatyö, jolloin nimikkeenä on nuorempi tutkija. Nuoremman tutkijan tulee olla jatkokoulutuskelpoinen, soveltuvan ylemmän yliopistotutkinnon suorittanut tai soveltuvan ulkomaisen koulutuksen, joka asianomaisessa maassa antaa kelpoisuuden vastaaviin korkeakouluopintoihin, suorittanut.

Tehtävään mahdollisesti kuuluva opetus ja ohjaus voidaan toteuttaa englannin kielellä.  

Tehtävä täytetään alustavasti ajalle 1.7.2019-31.8.2020. Mahdollisesta jatkosta sovitaan lisärahoituksen varmistuttua. 

Määräaikaisuuden perusteena on neliportaisen uramallin mukainen opetus- ja tutkimustehtävä ja määräaikainen hanketehtävä. (Tutkijatohtorin/nuoremman tutkijan tehtävään otetaan aina määräajaksi, johtosääntö 31§).

Tutkijatohtorin tehtävän palkkaus määräytyy yliopistojen opetus- ja tutkimushenkilöstön palkkausjärjestelmän mukaisesti vaativuustasolle 5 (2 935,55 €/kk). Nuoremman tutkijan tehtävän palkkaus määräytyy palkkausjärjestelmän mukaisesti vaativuustasoille 2-4 (€2033,29 – €2535,20/ kk). Tehtäväkohtaisen palkanosan lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on enintään 50 % tehtäväkohtaisesta palkanosasta.

Lisätietoja tehtävän osalta antaa: Akatemiatutkija Jukka Kekäläinen, sähköposti: jukka.s.kekalainen[a]uef.fi, puh. +358 50 467 4487 ja hakumenettelyn osalta: Henkilöstösihteeri Noora Hämäläinen, sähköposti: noora.hamalainen[a]uef.fi, puh. +358 50 409 0376

Uuden työntekijän tullessa yliopiston palvelukseen käytetään koeaikaa.

Sähköiseen hakemukseen tulee liittää:

– Ansioluettelo
– Julkaisuluettelo
– Kopiot tutkintotodistuksista ja kielitaitoa osoittavista todistuksista, ellei kielitaito ilmene tutkintotodistuksista
– Motivaatiokirje (englanninkielinen, enintään 2 sivua). Kerro kirjeessä, miksi tutkimusaihe kiinnostaa sinua ja miksi olisit sopiva henkilö tehtävään

Hakemus tulee jättää viimeistään 30.4.2019 sähköisellä hakulomakkeella.

Hakemuksen voit jättää klikkaamalla alla olevaa linkkiä ”täytä hakemus”.

POSTDOCTORAL RESEARCHER

Project and responsibilities

This Academy of Finland and Novo Nordisk-funded project involves studying genetics and molecular biology in bone metabolic diseases.

Please see https://www.helsinki.fi/en/researchgroups/metabolic-bone-diseases for more information. You will study the genetics of skeletal diseases and molecular biological consequences of skeletal disease in zebrafish models, primary cultures, and cultured cell lines. You will perform NGS data analysis and imaging and molecular biology analysis of the zebrafish and cells. You will also supervise Master’s/PhD students, prepare and publish scientific manuscripts, and write grant applications.

Qualifications

A successful candidate holds a PhD in life or biomedical sciences. Experience and qualification in genetics, biochemistry or animal physiology and working with cell cultures is obligatory. In addition, knowledge of molecular biology studies and imaging is essential. Knowledge of NGS data analysis, bone biology, skeletal diseases, and zebrafish studies will be advantageous.

The salary will be based on the Universities salary scheme for teaching and research personnel. A successful candidate is expected to start in May 2019, or according to the agreement.

Application and questions should be sent to minna.pekkinen(at)helsinki.fi or outi.makitie(at)helsinki.fi, with the subject line “open postdoc position.” Applications are invited immediately, and the position will be filled when a suitable candidate is found.

PhD student – University of Helsinki and Folkhälsan Research Center, Biomedicum in Meilahti, Helsinki, Finland

A Ph.D. student position is available at the University of Helsinki and Folkhälsan Research Center, Biomedicum in Meilahti, Helsinki, Finland. Our research involves the clinical and genetic characteristics of osteoporosis, skeletal dysplasias, early-onset obesity, and mineral metabolism. Please see https://www.helsinki.fi/en/researchgroups/metabolic-bone-diseases for more information.

We offer you:

•    an opportunity to work in a high-quality group of bone researchers

•    a chance to be involved in cross-field science and develop new techniques for the research of

     bone diseases in cell biology, molecular biology, clinical medicine, and animal work

•    an inspiring research environment on the largest biomedical research campus in Finland

•    a chance for completing a Ph.D

•    financial support through a grant with the possibility of applying for University Graduate

     Schools later on

What is expected of you:

•    MSc degree in biological or biomedical sciences field

•    high motivation level and work morale

•    capability to work both independently and in group

•    to manage overlapping projects

•    previous experience in genetics, cell biology or molecular biology is required

•    experience in laboratory work with cell culture

•    Skills and training in working with model animals (zebrafish) are an advantage. The project

     will involve animal work

•    adequate written and oral skills in the English language

•    a possibility of interviewing at Folkhälsan Research Center in person (not via Skype)

The start time is negotiable, but spring 2019 is preferable. Please address your queries and applications in English, with CV, to Minna Pekkinen, minna.pekkinen(at)helsinki.fi, tel. 050 4485670, 31.3.2019 at the latest.

Cancer research scientist – Phenex Pharmaceuticals AG, Heidelberg

https://www.phenex-pharma.com/pdf/CancerResearchScientist_0319.pdf

Projektitutkija, farmasia/biofarmasia – Itä-Suomen yliopisto, Kuopion kampus

https://rekry.saima.fi/certiahome/application_edit_welcome.html?field_id=0&job_name=Projektitutkija%2C+farmasia%2Fbiofarmasia&job_id=7045&jc=16&lang=en&place_id=108&did=5600

Haettavana on

Projektitutkija, farmasia/biofarmasia, farmasian laitos, Kuopion kampus

Haettavana olevaan tehtävään liittyvä tutkimus on osa EU:n Horisontti 2020 -puiteohjelman rahoittamaa EDCMET-hanketta (https://cordis.europa.eu/project/rcn/218991/factsheet/en), jonka tavoitteena on selvittää hormonihäirikköjen metabolisten haittavaikutusten mekanismeja ja kehittää tutkimuksessa tarvittavia menetelmiä. Projektitutkijan työnkuvaan kuuluvat tutkimuksen tekeminen ja tutkimuksen avustavat tehtävät hankkeessa. Ensisijaisena työtehtävänä on kehittää ja optimoida tumareseptoriaktivaation tutkimiseen tarvittavia solupohjaisia ja reportterigeenin aktiivisuuden mittaamiseen perustuvia menetelmiä. Tehtäviin kuuluvat myös menetelmissä tarvittavien DNA-konstruktien kloonaus, reagenssien valmistus, solujen ylläpito ja muut yleiset laboratoriotehtävät. Projektitutkijan odotetaan tarvittaessa osallistuvan myös muihin ryhmän tutkimustehtäviin.

Tehtävään valittavalta henkilöltä edellytetään suoritettua filosofian maisterin tai vastaavaa tutkintoa biokemiasta, molekyylibiologiasta, toksikologiasta tai muulta soveltuvalta alalta. Henkilöllä tulee olla syvälliset tiedot ja aiempaa käytännön laboratoriokokemusta puhdastilatyöskentelystä ja nisäkässoluviljelystä sekä vähintään perustiedot transfektiomenetelmistä, reportterigeenianalyyseistä ja plasmidikloonauksesta. Tehtävän menestyksekäs hoitaminen edellyttää omatoimisuutta, kykyä itsenäiseen tiedonhakuun ja töiden suunnitteluun, kykyä tehdä yhteistyötä poikkitieteellisessä ja kansainvälisessä ympäristössä sekä hyvää suomen ja englannin kielen kirjallista ja suullista taitoa.
Tehtävä täytetään määräajalle 1.4.2019-31.12.2020. Määräaikaisuuden perusteena ovat määräaikaiset tutkimustehtävät hankkeen osaprojektissa.
Tehtävän palkkaus määräytyy yliopistojen opetus- ja tutkimushenkilöstön palkkausjärjestelmän mukaisesti vaativuustasolle 2 (2033,29 €/kk). Tehtäväkohtaisen palkanosan lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on enintään 50% tehtäväkohtaisesta palkanosasta.

Lisätietoja: projektitutkija Jenni Küblbeck, 029 4454111, jenni.kublbeck@uef.fi, ja hakumenettelyn osalta  hallintosihteeri Seija Koistinen, 029 4454324, seija.koistinen@uef.fi. 
Uuden työntekijän tullessa yliopiston palvelukseen käytetään koeaikaa.

– ansioluettelo
– julkaisuluettelo
– kopiot tutkintotodistuksista ja kielitaitoa osoittavista todistuksista, ellei kielitaito ilmene tutkintotodistuksista
– motivaatiokirje (max 1 sivu)
– muut dokumentit, jotka voivat vaikuttaa valintaan (max 3 sivua)
– kahden suosittelijan yhteystiedot

Hakemus tulee jättää viimeistään 15.3.2019 sähköisellä hakulomakkeella.

Early stage graduate student positions on state-of-the-art infection research at the Faculty of Medicine, University of Helsinki

Two positions available at the Faculty of Medicine to study the role of microbes and microbial infections in blood malignancies. Both positions provide ample opportunities to develop expertise on next-generation sequencing -based diagnostics, computational genomics, and infectious diseases together with the top national clinicians, haematologists, bioinformaticians, microbiologists, and geneticists.

Particularly, we are looking for:

1) A student with a good knowledge on wet laboratory techniques and enthusiasm to develop advanced sample preparation solutions for the analysis of complex hostmicrobe samples. The candidate has a background in microbiology, biotechnology, or genetics, and is familiar with the major wet-laboratory techniques in molecular biology. He or she can design and conduct laboratory experiments independently and has interest in developing skills in the analysis of giga-size biodata available in the laboratory. Prior work experience in a research laboratory is an advantage as well as experience in working with RNA, DNA, and/or clinical/human samples.

2) A student with experience in bioinformatics and/or analysis of large-scale biodata. The candidate has a background in bioinformatics, computer science, engineering, or genetics and masters fluently at least one of the following: Python, Perl, R, C++, or Java. The applicant has a proven ability to operate in Linux environment and is interested in developing computational solutions for the integrated analysis of genetic and clinical data and sequencing-based analysis of host-microbe infections. Experience in parallel programming and machine learning is an asset as is prior work experience on analysis of next generation sequencing data and/or large biodata collections.

Both candidates must have good skills in written and spoken English. They should apply critical thinking, have a proactive mindset, and enjoy working in a multi-disciplinary team. They should have excellent communication and interpersonal skills and are expected to communicate results to diverse audiences. The positions are funded by project grants from the Academy of Finland, the Finnish Funding Agency for Innovation / Business Finland, and The Finnish Cultural Foundation. The appointments are initially for 6 months with a possibility of extension.

For further information, please contact Dr. Teija Ojala (teija.ojala(at)helsinki.fi) or Dr. Matti Kankainen (matti.kankainen(at)helsinki.fi). To apply for the position, please send your motivation letter and CV, including a list of publications and contact information for two references to Dr. Kankainen.

Applications will be reviewed and considered as they are received. Application deadline is 24.03.2019.