Ajankohtaista

Erikoistuvan sairaalasolubiologin sijainen, 6kk

Haemme Helsinkiin HUSLAB: iin Meilahden patologian laboratorioon sijaista erikoistuvan sairaalasolubiologin vakanssiin 6kk ajaksi (1.6-31.12.2019). 

Paikka tullaan täyttämään nopealla aikataululla, joten jos olet kiinnostunut ilmaise se sähköpostilla kummallekin sairaalasolubiologeistamme: 

olayinka.raheem@hus.fi ja mia.kero@hus.fi. Tiedustelut ainoastaan sähköpostitse. Eduksi katsotaan solubiologian pääaineopinnot. Hakija voi olla valmistunut tai juuri valmistumassa oleva henkilö. Ennen valintaa pidetään sopiviksi katsomillemme henkilöille lyhyt haastattelu.

YT, Mia Kero

Sairaalasolubiologi, FL

Haartmaninkatu 3C, C229

00290 Helsinki

+358504270966

Director, Disease Biology Neurosciences – Orion, Turku

https://www.linkedin.com/jobs/view/1269623345/?recommendedFlavor=IN_NETWORK&refId=51f40857-5328-4e9b-8e89-73ac0be35ead&trk=eml-jymbii-organic-job-card&midToken=AQFgumZyIt6sOQ&trkEmail=eml-jobs_jymbii_digest-null-3-null-null-41f64x%7Ejvpm8geo%7E89-null-jobs%7Eview

Orion Corporation is a globally operating Finnish pharmaceutical company – a builder of well-being. Orion develops, manufactures and markets human and veterinary pharmaceuticals and active pharmaceutical ingredients.

Description of position

• Supervise and build up the Disease Biology team of Senior Scientists and Scientists in in vivo and in vitro research
• Ensure the resourcing and optimal plans to forward the research projects in NDD and pain
• Build-up of target validation from in vitro to in vivo and bring in new technologies and protocols
• Contribute to translational models, and how to translate from bed-to-bench and back
• Generate and evaluate new project ideas with the other pain/NDD scientists
• Work closely with NDD and pain directors and VP of CNS TA to build the CNS Strategy and portfolio

You will be based in Turku, Finland and report to the Vice President of R&D, CNS Therapy area.

The job title will depend on the experience and competences, and other title options can be considered.

Description of the unit 

Orion’s pharmaceutical innovations are created within its R&D organization, including e.g. non-clinical research, clinical development, formulation development and medical affairs. The organization employs top professionals in the field of drug molecule development and optimization.

Therapy area of the Central Nervous System (CNS) is accountable for the research and development of medications for neurodegenerative diseases (NDD) and chronic pain at Orion. Our team builds the R&D CNS portfolio and CNS strategy in close collaboration with business and all R&D global functions. You will be based in Turku, Finland and report to the Vice President of R&D, CNS Therapy area. The job title will depend on the experience and other title options can be considered.

We offer

We offer exciting opportunities to create and have an impact to the future therapies for patients.

In Orion we have a highly interesting R&D pipeline and enthusiastic working environment with opportunities to use your own strengths to build your competence development and career. As an expert of your own field you will be a member of multi-disciplinary team jointly innovating and developing new treatments for the patients. Appreciation of colleagues and continuous development are part of our core values.  The culture of Orion R&D is informal and we enjoy working together.

We are passionate about the patient welfare and serve as The Voice of Science and the Patient – if this inspires you too – join us!

In many fields, Finland is considered a leader in the world (see the following link by copying it to your web browser) and is a great country to live in.
http://www.huffingtonpost.com/ira-kalb/finland-is-still-the-worl_b_10774930.html

Requirements PhD in neurosciences/pain with at least 10 year Post doctoral experience Large network in neurosciences/pain and smoothly collaborating with Internal & External partners (academic and industrial, etc.) Industry experience is an advantage Excellent organizational and people leadership skills Successful experience and interest in heading a large team and supervising Profound expertise of ALS, PD and/or pain related disease mechanisms Deep interest, expertise, experience and skills in some of the following entities: Establishing, characterizing and implementing state-of-the-art cellular models to unravel disease mechanisms in pain and/or neurodegenerative diseases (PD & ALS) Establishing, characterizing and implementing state-of-the-art animal models to unravel mechanisms in pain and/or neurodegenerative diseases (ALS, PD) such as Tg, KO, KI Molecular and cell biology techniques, Gene editing & viral vector technologies and Microscopy & imaging techniques

Please send your application latest on 31 May 2019. For further information, please call Dr. Taru Blom, VP R&D at following times: May 17 at 15:00-16:00 (FIN), May 20 at 15-16:30 (FIN) or May 22 at 13-14 (FIN) or May 29 at 14-15 (FIN). Telephone +358-50-9667836. Interviews are planned to be started during the application period.

Orion Corporation operates in more than 25 countries, where we Orionees, 3200 in total, work in all kinds of positions. We encourage people to develop their competences, and offer opportunities to affect own job description and create own career path at Orion.

Accessioning Lab Associates (summer job) – Blueprint Genetics, Helsinki

https://www.linkedin.com/jobs/view/1234904331/?recommendedFlavor=IN_NETWORK&refId=28e99985-432d-4a8d-b331-8acdd65c83da&trk=eml-jymbii-organic-job-card&midToken=AQFgumZyIt6sOQ&trkEmail=eml-jobs_jymbii_digest-null-11-null-null-41f64x%7Ejv5jcezj%7E46-null-jobs%7Eview

Introduction

Blueprint Genetics is on a mission to bring world-class genetic knowledge to mainstream healthcare. Our Helsinki Production Services Team is now looking for new Accessioning Lab Associates to work at our sample reception during the summer holidays (May – Aug 2019). We are a team of specialists that have expertise in the sample quality control and order reviewing in the sample accessioning process. Our team works in close collaboration with Clinical Laboratory and Client Services Teams.

Job description

In this position, your main tasks include order reviewing, sample reception and accessioning. You confirm that samples arriving to our Helsinki laboratory comply with our sample requirements and that the enclosed paperwork is sufficient. Your work is very detail-oriented and guided by precise guidelines. You work closely with Client Services Team to make sure that the customer is contacted about any missing or needed information. You work closely with Clinical Laboratory to give them quality material for the sequencing runs.

Qualifications

You should have a Laboratory Technician / B.Sc. level degree, or similar in biosciences or biotechnology or another related field. The ideal candidate has great written and verbal skills in Finnish and English and is able to work in our International environment – as well as review and process orders in English. Working together for a common goal motivates you. You have superior attention to detail and strong organization skills. You are enthusiastic to learn more about our production processes and have the passion to help develop them further.

Previous experience in laboratory accessioning operations will be an asset, but not required, since you will be offered proper training and support to get started.

What we offer

At Blueprint Genetics, you get to be a part of our global team of innovative, dynamic and motivated people. You will be working at the forefront of health and life sciences, in the company that makes a real difference for people’s health.

We offer you a rapidly evolving working environment, where you can learn and grow together with the company and great colleagues!

This position is a fixed-term, full-time summer job with a possibility of extension.

Please, submit your application and CV along with your salary request latest on 24th of May. Interviews and recruitment will be done as soon as suitable candidates are found.

Since you might have some additional questions about the position, you can contact Sini Vuorensyrjä, Production Services Team Manager by email sini.vuorensyrja(at)blueprint genetics.com.

Doctoral Student in Development of Biosensors for Glioma Treatment – University of Oulu

https://www.linkedin.com/jobs/view/1247203892/?refId=VYv5h1FaRdeBNkeegP1pNw%3D%3D

Doctoral Student in Development of Biosensors for Glioma Treatment

The University of Oulu is one of the largest universities in Finland. With about 14 000 students and approximately 3 000 employees it is a vibrant international scientific community. By combining multidisciplinary research and education, high-level infrastructure and wide cooperation with international research and educational institutes, companies and the public sector it has created a significant research and innovation hub of “Science with Arctic Attitude”. More information .

The position is located in the Faculty of Biochemistry and Molecular Medicine of the University of Oulu (

Subject Field And The Description Of The Position

Glioblastoma Multiforme (GBM) is the most malignant primary brain tumor with a median survival time of little bit more than one year. High complexity of GBM requires development of novel diagnostic and therapeutic approaches combining molecular oncology, cell biology, nanobiology, and bioingeneering. The project aims to develop such approaches by generating implantable 3D cell organoids. Various in vivo and in vitro assays, OMICS studies, molecular cloning and analysis of secreted extracellular vesicles will be applied in the current project. The details of the research project will be mutually agreed upon, based on the qualifications, interests, and expertise of the candidate. Candidates with expertise on neurobiology and solid knowledge and working experience with cell biology and/or molecular biology will be preferred.

The duration of the position is initially for 2 years with the possibility to be extended for 2 more years. The starting date is July 1, 2019, or as soon as possible thereafter.

Required Qualifications And Assessment

The successful applicant must hold a recent MSc degree in life sciences. Candidates whose master thesis will be submitted by the application deadline will also be eligible. Fluent oral and written English skills as well as good communication and teamwork skills are required. Demonstrated experience in writing scientific publications, potential in acquiring supplementary funding and teaching experience will be taken as merits.

A six-month trial period will be effective in the beginning of a contract.

Salary

The salary is in accordance with the University salary system (for teaching and research personnel) levels 2-4. In addition, there is a share increase at most, 50% of the base salary, which is based on personal achievements and performance.

Application Procedure

The following documents must be attached to the application (in English)

• Motivation letter (1 – 2 pages)
• CV with the names and contact details of 2 – 3 referees
• Full publication list
• Copies of relevant official degree
  
  

Applications, together with all relevant enclosures, must be submitted using the electronic application form by May 15 st , 2019. Applications sent by email will not be considered.

Interview

The top candidates for the post may be interviewed and asked to present their scientific work and experience.

For Further Information Regarding The Filling Of This Post

Dr Seppo Vainio, Professor, e-mail: seppo.vainio(at)oulu.fi

Dr Anatoliy Samoylenko, Adj. Professor, e-mail: anatoliy.samoylenko(at)oulu.fi

Tiina Hurskainen, HR Manager, email: tiina.hurskainen(at)oulu.fi

Product Manager, Animal Health Swine Portfolio – Thermo Fisher Scientific, Finland

https://duunitori.fi/tyopaikat/tyo/product-manager-animal-health-swine-portfolio-stshe-9606996

Työpaikkakuvaus

About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with revenues of $20 billion and 67,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Our four premier brands – Life Technologies, Thermo Scientific, Fisher Scientific and Instrument and Enterprise Services – offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support.

Position Summary:

Product Manager, Animal Health Swine Portfolio
Location: Europe, EMEA – remote

A driven Product Manager who will manage a portfolio of on-market swine diagnostic products, seek a deep understanding of customer needs, and assist in developing the animal health roadmap. S/He will serve as product champion and be responsible for life cycle management, training, and support.

Responsibilities:

• Manage the assigned on-market swine product portfolio and the overall product life cycle including determining discontinuation and/or product refresh.
• Define product line strategy based on customer needs, market research and business unit goals
• Understand customer needs then translate them to product specifications that can be leveraged in an effective go-to-market strategy.
• Work cross-functionally to ensure revenue, margin, customer satisfaction, and growth goals are achieved
• Forecast sales, guide worldwide pricing, and work with market development on product demand generation strategies
• Contribute to fiscal planning and budgeting as it relates to growth and evolution of the product portfolio
• Provide ongoing product Sales training and customer support.
• Work as part of a dynamic team of R&D, program management, marketing, technical, and business development professionals to execute our common mission
• Serve as a key liaison between internal customers (Sales, R&D, Marketing, Manufacturing, etc) and external customers (end users, suppliers, etc).
• May be required to perform other related duties as required and/or assigned

*Minimum Qualifications (must have):

• Bachelor’s Degree (B.S./B.A.) in a scientific discipline (molecular biology, genetics or biochemistry preferred).
• At least five years of relevant experience in product management and/or strategic marketing.
• Understanding of production animal industry
• Willing to travel and work with global teams
• Proficient in understanding, analyzing and summarizing comprehensive and complex technical, financial, market and research information/data.
• Strong communication skills
• Very good English skills
• Understanding of product management and marketing.
• Is customer-centric and keenly aware of markets, trends and competitors
• Greets challenge and change as opportunity
• Inspires, motivates and collaborates with others
• Ability to travel globally 30-40% of time

*Preferred Qualifications (nice to have):

• MBA a plus but not required.

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

Tuotekehitystutkija – Oy Medix Biochemica Ab

https://tyopaikat.oikotie.fi/avoimet-tyopaikat/tuotekehitystutkija/1264395

Etsimme tutkijaa vasta-aineiden tuotekehitykseen Espooseen

Etsimme tiedonjanoista tutkijaa vakituiseen työsuhteeseen kehittämään vasta-aineita diagnostiikkateollisuuden tarpeisiin. Tarjoamme monipuolisia alan työtehtäviä osana työstään innostunutta tuotekehitystiimiä. Tutkijan työhön kuuluu uusiin projekteihin liittyvää tieteellisen tiedon hakua ja yhdistämistä sekä vasta-aineiden erilaista immunokemiallista karakterisointia, mm. ELISA-menetelmillä ja BLI-teknologiaa hyödyntäen. Myös immunisointien suunnittelu ja toteuttaminen kuuluvat tehtävään. Koesuunnittelu, tuotekehityslaboranttien ohjeistaminen, tulosten tulkinta sekä raportointi ovat oleellinen osa työtä.

Edellytämme:

• kokemusta immunologisista menetelmistä sekä niiden kehittämisestä
• reipasta ja huolellista otetta työhön, organisointikykyä, ryhmätyötaitoja ja paineensietokykyä
• kykyä selkeään ja tarkkaan dokumentointiin
• erinomaista suomen ja englannin kielen taitoa
• ylempää korkeakoulututkintoa biokemiasta, bioteknologiasta tai vaihtoehtoisesti tehtävään soveltuvalta alalta

Arvostamme:

• kokemusta BLI-teknologiasta
• laatujärjestelmien tuntemusta
• kokemusta koe-eläintöistä

Hakemukset palkkatoiveineen 12.5.2019 mennessä.

Lisätietoja tehtävästä antaa Teknologiapäällikkö Suvi Eklin puh. 040 8305 355, perjantaina 3.5. klo 13:30 – 14:30 sekä torstaina 9.5. klo 9:00–10:00.

Työ on vakituinen. Työn aloitus sopimuksen mukaan.

Regulatory Affairs Specialist / Assistant – Thermo Fisher Scientific, Vantaa

https://duunitori.fi/tyopaikat/tyo/regulatory-affairs-specialist-assistant-stshe-9561234

Työpaikkakuvaus

Regulatory Affairs Specialist / Assistant
Vantaa, Finland

Our in vitro diagnostic medical devices are regulated products which need marketing authorization before sales can commence. We are looking for a Regulatory Affairs Specialist /Assistant to coordinate product registrations in co-operation with our commercial organization and distributors. The selected candidate will work as an integral part of a multidisciplinary Quality Assurance and Regulatory Affairs team to coordinate and compile product registration packages to e.g. India and other Asia-Pacific countries. This is a fixed-term position for approximately 3-4 months.

What can we offer

• Opportunity to gain experience in regulatory affairs and know-how in international regulations that is a core competence in medical device industry
• Work in a multi-disciplinary and international setting both with Thermo Fisher Scientific colleagues and our customers
• Possibility to work with our diverse in-vitro medical device product portfolio including clinical chemistry products and analyzers as well as laboratory automation solutions

How you’ll get there

• M.Sc or B.Sc degree in microbiology, biology, analytical chemistry, biochemistry, engineering or related field, or a Student of the mentioned scientific disciplines
• Motivation to learn and interpret different regulations related to in vitro diagnostic medical device industry
• Excellent verbal and written communication skills in English
• Sound organizational skills and attention to detail in documenting
• Self-driven attitude with persistence to take projects to the completion

Please send in your application, including a cover letter and CV. Please apply via https://jobs.thermofisher.com/ by 12.5.2019. Reference: 93305BR. Please apply as soon as possible, the position will be filled as soon as suitable candidate is found.

Senior / Post-doctoral Scientists (Cancer and Immunotherapy) – Kuopio Center for Gene and Cell Therapy (KCT)

https://www.sympahr.net/public/pq.aspx?1625e2a6&lang=en-US

Kuopio Center for Gene and Cell Therapy (KCT) is a world-renowned research institute located in Kuopio, Finland. Our mission is to conduct high-level research on basic and translational fields of gene- and cell therapy. The center’s niche is in the interface between academic research and the commercial biotechnology industry. KCT provides an exciting environment for applied research, discovering, establishing and developing them through Phase I clinical trials and utilizing some of the most advanced analytical and mechanistic proof-of-principle approaches in the sector.

We are seeking for two enthusiastic, highly motivated and skilled candidates with a background in disease or tumor biology, immunology and biomarker research for Senior Scientist (post-doctoral) role in Immunotherapy Program in Kuopio Center for Gene and Cell Therapy. Successful candidates will have an opportunity to work in one or more of the areas as project manager: T cell and NK cell biology, tumor microenvironment and/or discovery of novel tumor targets. The candidate will contribute to the projects experimentally and scientifically, provide his/her expertise, take-leading role in internal reporting and continue in a laboratory-focused role. The candidate will have a proven track record of scientific productivity and ability to participate in multidisciplinary and innovative research. The individual will participate in strategic discussions, national and international collaborations and coordinate project activities.

The selected candidates will be focused in work leading to the development of novel immunotherapies. The responsibilities include:

• Effectively collaborate within the research center and national/international collaborators.
• Lead the design and implementation experimentation.
• Supervise young scientists and technicians working in the project.
• Generate, analyze and interpret data. Demonstrate a high level of initiative in troubleshooting experiments and accurate data analysis. Objectively interpret data and provide conclusions regarding project results and direction.
• Actively report research results and novelties in the field.

Qualifications: PhD in immunology, molecular/cell biology, cancer biology, pharmaceutical sciences or biomarker discovery OR MSc with at least 10 years of relevant experience. Knowledge on high-throughput experimentation and large data analysis is positively evaluated. Strong hands-on technical skills (e.g. primary cell isolation and culture, flow cytometry, live cell imaging) and reporting in research. Ability to multitask, manage and develop complex projects. Effective written and spoken English language skills. Excellent interpersonal and teamwork skills.

We offer an inspiring multicultural environment, constructed of our enthusiastic, highly skilled and experienced personnel in gene and cell therapy. Kuopio Center for Gene and Cell Therapy has established working links with the gene and cell therapy manufacturer FinVector, the A.I. Virtanen Institute for Molecular Sciences, the University of Eastern Finland, the National Laboratory Animal Center, and Kuopio University Hospital. These are situated on the same Kuopio health science focused campus, the capability of which to undertake gene and cell therapy research is made complete by the presence of the office of the Finnish Medicines Agency (Fimea). Finland has been ranked as the happiest country in the world and vibrant Kuopio, is rated as Finland’s best city to live in. It offers a safe living environment, friendly atmosphere and clean nature.

More information Cell Therapy Unit Director Tuija Kekarainen (tel. +358405376603 or tuija.kekarainen@kct.fi) and HR Director Johanna Pirinen (Johanna.pirinen@kct.fi). 

Please send your application before 20th May 2019.

The Department of Anesthesiology at Washington University School of Medicine welcomes applications for a tenure-track faculty position in The Center for Clinical Pharmacology

The Department of Anesthesiology at Washington University School of Medicine welcomes applications for a tenure-track faculty position in The Center for Clinical Pharmacology, a multi-institutional research center established in partnership with with St Louis College of Pharmacy in 2015.  Successful candidates will join an existing group of faculty with research interests in basic and translational pharmacological science.

The goal of the Center for Clinical Pharmacology is to focus on human-oriented research that spans the continuum of basic to translational and clinical research, specifically through research that improves the use of both current and new therapeutics and diagnostics. The Center faculty brings vast experience in multiple aspects of drug discovery including drug mechanisms, medicinal chemistry, PK/PD, pharmacogenomics and drug development.  The Center has a deep interest in “chemical biology”, pharmacology, behavior and neuroscience.

This position is targeted at established investigators at the Associate Professor or Professor levels. Strong preference will be given to candidates currently conducting translational and/or clinical research. Additional leadership opportunities are available dependent upon experience. Successful candidates will be expected to direct an active extramurally funded research program and participate in graduate and/or postdoctoral education, with faculty appointments at both Washington University School of Medicine and the St Louis College of Pharmacy. Teaching opportunities are readily available but requirements are minimal, permitting a strong focus on research. Generous startup funds and newly constructed lab space are available. 

Candidates must have a doctoral degree (PharmD, PhD, MD or equivalent) and a demonstrated record of accomplishment as an independent investigator. Applications will be reviewed as received until the position is filled. 

To apply, send a curriculum vitae, a summary of past research activities, future research plans, and the names of three references to:

Karen Seibert, PhD, Executive Director, via email to clinpharm@anest.wustl.edu.
For more background see www.clinicalpharmstl.org

The Department of Anesthesiology at Washington University School of Medicine in St Louis fosters an academic culture in which clinical care, research, and education are seamlessly integrated. The department makes major contributions to the science of anesthesiology through its basic science and clinical science programs, which are heavily focused on innovative education and comprehensive, personalized clinical training.

Founded in 1864, St. Louis College of Pharmacy is the third-oldest and 10th-largest college of pharmacy in America. The College provides students unparalleled opportunities to learn through research, internships, and other hands-on learning experiences with their neighbors Barnes-Jewish Hospital, Washington University School of Medicine, and St. Louis Children’s Hospital.

Postdoctoral position(s) available on summer/autumn 2019 at Harvard Medical School and Cancer Center at Beth Israel Deaconess Medical Center

Harvard Medical School and Cancer Center at Beth Israel Deaconess Medical Center

Postdoctoral position(s) available on summer/autumn 2019

Our lab studies how cancer cells develop drug resistance, and more specifically, how tumor microenvironment provides support and protection for tumor cells. Our aim is to develop better treatment strategies to overcome this tumor microenvironment mediated drug resistance. 

To investigate these topics we utilize both normal and cancer cells in 3D organoid culture systems, which mimic the architecture and organization of tissues. We use this platform in co-culture systems to understand how stromal and epithelial cells communicate with each other, and have also adopted the use of organoids for larger scale methodologies, such as proteomics, metabolomics, RNA-seq and ribosome foot-printing experiments to gain insight into multiple mechanisms by which cancer cells become drug resistant in 3D environments.

Our group is located in the Longwood medical area, at the Beth Israel Deaconess Medical Center, with several established collaborations with groups in the Harvard Medical School, MIT, Yale, Weill Cornell and MD Anderson. This environment provides unique opportunities for performing cutting-edge science, training in state-of-the-art technologies, forming new collaborations, and developing new technologies.

We are looking for highly motivated individual(s) who have recently finished (or about to finish) their PhD, with excellent communication and critical thinking skills, and who are able to work as part of a team. Training in cell biology, molecular biology and microscopy, and basic understanding of cell signaling networks is required.

For more information, please visit our lab web page: http://www.muranenlab.org

Or refer to the relevant publications: Muranen et al. Cancer Cell 2012, Muranen at al. Cancer Research 2016, Muranen et al. Nature Communications 2017 (http://rdcu.be/oqQ6).

Please send a cover letter with short description of your research interests and previous experience, current CV, and names of three references to tmuranen@bidmc.harvard.edu.