28.3.2018 | Ajankohtaista
We are looking for a team leader or senior researcher in computational epigenomics to join our multidisciplinary and international team of experts in the Computational Biomedicine group at Turku Bioinformatics Unit, Turku Centre for Biotechnology, University of Turku and Åbo Akademi University. The position is for two years, starting from 1.5.2018. Starting date is negotiable and continuation of the project is possible.
Turku Centre for Biotechnology (www.btk.fi) is a joint department of University of Turku (www.utu.fi) and Åbo Akademi University, providing high-end technologies and expertise to academic and industrial researchers and a stimulating multidisciplinary and international research environment. Turku Bioinformatics Unit and the Computational Biomedicine Group of Dr. Laura Elo (www.btk.fi/research/research-groups/elo) develops computational data analysis tools and mathematical models for biomedical research, with the eventual goal of improving the diagnosis, prognosis and treatment of complex diseases, such as diabetes, cardiovascular diseases and cancer. A specific focus is on analysing and interpreting data generated by modern high-throughput biotechnologies, such as deep sequencing and mass-spectrometry proteomics.
The work involves processing and analysing high-throughput next-generation sequencing data to answer complex biomedical questions. The specific focus area is epigenomics in close collaboration with the Finnish Functional Genomics Centre. The projects involve development and application of computational and statistical methods for the analysis of high-dimensional molecular and clinical datasets with focus on complex diseases. In addition to method development, the work covers implementation and benchmarking of existing tools and workflows. The candidate will work in a multidisciplinary team with backgrounds in mathematics, statistics, computer science, bioinformatics, biology and medicine, ensuring that there are competent additional personnel to assist in the projects as needed. He/She will also be tightly connected with the national and international collaborators, including a close connection to clinical and experimental teams. The team leader/senior researcher has the opportunity to target the research according to his/her own research interests within the projects running at Turku Bioinformatics Unit and to lead a team within the Unit. The salary is in accordance with the university salary system (for teaching and research personnel) level 5-7 where the work specific salary component is 2865.30-3851.33€/month. In addition, there is a share increase based on personal performance, which is at most 46.3% of the base salary. There is a trial period of four months.
We are looking for highly motivated scientist with expertise in bioinformatics, biostatistics, machine learning and/or epigenomics. We will consider candidates with outstanding potential and established excellence in research, proven by scientific publications in high impact international journals. Particular attention is paid also to success in research funding applications. The candidate should have high level of motivation, self-initiative and independency. The candidate should hold a PhD degree. An optimal candidate has international research experience and experience in supervision of students. Good communication skills in English, both oral and written, are essential. Experience with R, Matlab or other mathematical software is required.
The applications should be submitted at the latest on 15.4.2018 using the electronic system.
27.3.2018 | Ajankohtaista
R&D Scientist Molecular Food Safety – Thermo Fisher Scientific, Vantaa
Job Description
As the world’s leader in serving science, Thermo Fisher Scientific is a driving force in the research, healthcare, industrial and applied markets, generating more than USD 20 billion in annual revenue. No other company can match our range of customer touch points – technologically, geographically or commercially. We help our customers in finding cures for cancer, protecting the environment, making sure our food is safe and moving forward with thousands of important projects that improve millions of lives. At Thermo Fisher Scientific, each one of our 65,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission – enabling our customers to make the world healthier, cleaner and safer.In Finland we have over 800 employees in Vantaa and Joensuu. We employ experts in several different functions such as production, instrument and reagent manufacturing, R&D, marketing, sales, quality, support functions and supply chain. We hire experts in different engineering fields, chemistry, microbiology and bioinformatics. Vantaa site is located close to the Vantaankoski railway station. Our extensive range of products developed and manufactured in Finland includes pipettes, microplate instruments, magnetic particle processing systems as well as clinical chemistry and industrial chemistry analyzers, laboratory automation solutions and food safety kits. Please find more information on www.thermofisher.com
R&D Scientist Molecular Food Safety
Vantaa, FinlandThermo Fisher Scientific is currently recruiting for a R&D Scientist to our Microbiology Division (MBD) R&D team. The position is for a fixed term maternity leave cover starting in May 2018 and ending in August 2020.R&D Scientist will be part of the molecular food safety team responsible for designing and developing new molecular diagnostic products to complement the current microbiology product range.We are looking for a proactive, self-driven, result oriented team player. You enjoy working with high technology products and driving multiple initiatives at the same time. You want to develop yourself and the way of working. We offer motivating tasks in innovative and international working environment.
Key Responsibilities
- Early-stage research on real-time PCR reagents to be used in microbiology diagnostics.
- Executing projects in agreement with product specification and to ensure timely delivery of the projects.
- Planning and conducting experiments, reporting the results, maintaining formal reports and accurate laboratory records according to internal guidelines.
- Fulfilling the responsibilities of the position as defined in the Company Health, Safety and Environmental policies and associated Codes of Practice.
- Communicating observations, presenting data and giving project updates to the food safety R&D team in timely manner.
- Performing other responsibilities to support the needs of the department as assigned.
Experience/Qualifications/Qualities
- Master degree (M. Sc.) with several years of research experience in molecular biology and microbiology.
- Previous experience and in depth knowledge of microbiological techniques, sample preparation, real-time PCR, enzyme technology and Next Generation Sequencing is strongly preferred.
- Knowledge of scientific instrumentation and various software applications related to molecular biology. Experience on instrumentation or software development is preferred.
- Hands-on experience with R&D product development work and/or scientific work.
- Strong working knowledge of Windows based applications, internet technology, and statistical analysis software.
- Strong communication and inter-personal skills.
- Excellent planning and execution skills to handle and efficiently manage workload in multiple projects and meet timelines.
- Good spoken and written English and Finnish.
We look forward to receiving your application, including a cover letter and CV and a salary request in English. Please apply via http://jobs.thermofisher.com/. Reference: 64527BRPlease apply by the 1st of April.At Thermo Fisher Scientific, each one of our 65,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission – enabling our customers to make the world healthier, cleaner and safer.Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
26.3.2018 | Ajankohtaista
Open positions in PhagoMed Biopharma GmbH (Vienna, Austria)
· Group Leader Phage Research (Group Leader/ Senior Postdoc level), to lead a team of researchers in our lab
· Phage Research Technical Assistant, to complement our team
PhagoMed (www.phagomed.com) develops pharmaceuticals and other categories of medicinal products on the basis of bacteriophages. We build on the clinical experience in treating patients with phages (Helsinki 37) of our co-founders, Prof. Dr. Burkhard Wippermann and PD Dr. Andrej Trampuz. Our initial target indications are periprosthetic joint infections (mainly S. aureus) as well as urinary tract infections (mainly E. coli). PhagoMed was incorporated in November 2017 in Vienna and has secured financing for 2+ years from private investors as well as the Austrian government. The development program will be run in part through contract research with academic partners and CROs. For specific work packages central to the development program, we have an own laboratory in Vienna, for which we are seeking to fill the positions mentioned above, as soon as possible.
If you are interested to learn more, please contact via mail or telephone:
26.3.2018 | Ajankohtaista
COMPUTATIONAL BIOLOGIST (BIOINFORMATICIAN) POSITION IN BIOMEDICUM FUNCTIONAL GENOMICS UNIT
Biomedicum Functional Genomics Unit (FuGU) is a core unit organization located in Biomedicum Helsinki with expertise in genome profiling and functional genomics technologies. FuGU provides academic and industrial clients access to a wide range of genomics and related computational data analysis services. The unit is one of the five Life Science Research Infrastructures in the HiLIFE Genome Analysis Infrastructure (HGI) platform and is also part of the Biocenter Finland Genome-Wide Methods network. The unit operates together with Oncogenomics research group at the Genome-Scale Biology Research Program, Research Programs Unit.
A Computational biologist (bioinformatician) position is immediately available in FuGU for up to three years until the end of 2020. The position gives you the opportunity to develop your skills in a wide range of areas of genomics and genome-wide biology. Your work will mainly focus on data pre–processing and analysis of next-generation sequencing and microarray data but will also involvedevelopment of customized data analysis services, management of FuGU IT infrastructure, implementation of quality assurance standards, participation in design of customer projects and teaching in Master’s program and Graduate school courses.
The candidate should ideally have an MSc or PhD in bioinformatics, computational biology, biostatistics or relevant fields. Previous experience with the analysis of next-generation sequencing data is required with proven competence in:
- Working in the Linux/UNIX environment (Essential)
- Working with R/RStudio (Essential)
- Background in DNA-seq and RNA-seq sequence alignment analysis (Essential)
- Good programming skills (Python, R) (Preferable)
- Basic knowledge of statistics (Preferable)
- Background in microarray data analysis (Preferable)
The candidate should also have excellent team working and communication skills. Successful implementation of your tasks will require ability to work independently and in a team of lab coordinator, research assistants and researchers. The position also requires active communication with other HiLIFE research infrastructures as well as customers coming from academia and industry.
The salary of a computational biologist will be based on levels 8-9 of the demands level chart for other personnel in the salary system of the Finnish universities. In addition, a salary component based on personal work performance will be paid.
To apply, please send covering letter, CV and names of two referees to Dr. Outi Monni, E-mail: outi.monni@helsinki.fi . The closing date of the application is Wednesday April 4th, 2018. The position is filled as soon as suitable candidate is found.
26.3.2018 | Ajankohtaista
We are currently seeking a post-doctoral researcher. Successful candidates will have shown outstanding biomedical research accomplishment and promise, and commitment to a career in academic and translational research. We are particularly interested in candidates with graduate or post-graduate (MD or PhD) level expertise in research on mucosal immunology, human milk, adaptive immunity, food allergy or other atopic diseases, or alternatively expertise on other areas of biomedical research that will be applicable to the abovementioned areas.
Our projects focus on 1) understanding the interaction between breast immune factors (antibodies, microbiome, oligosaccharides, metabolome, proteome) and epithelial or immune cells and/or gut microbiome, 2) immunoprofiling of the early infant immune system, and 3) tolerance development and homeostasis of mucosal immune system and microbiome, utilizing experimental models of immune activation and human samples in the context of mucosal exposure and/or breast milk immune factors.
The overall goal is to uncover factors related to immune protection provided by human milk and protection from atopic diseases including food allergy with ultimate goal in prevention.Prior experience in tissue culture, flow cytometry, ELISA, Luminex, microbiome and/or gene expression analysis is preferred. Excellent communication skills and fluency in spoken and written English is required. The postdoctoral position is with the Department of Pediatrics.
Applicants should submit a current Curriculum Vitae, along with contact information to 3 referees that we may request to write a letter of recommendation e-mail your Curriculum Vitae to: Kirsi Jarvinen, MD PhD (Kirsi_Jarvinen-Seppo@URMC.Rochester.edu ) or Antti Seppo, PhD (Antti_Seppo@URMC.Rochester.edu ). Check out
www.Golisano.urmc.edu/foodallergy
A postdoctoral position is open in the laboratory of Dr. Richard van Rijn in the Department of Medicinal Chemistry and Molecular Pharmacology in the College of Pharmacy at Purdue University to work on a recently NIH-funded R01 grant. The project proposes to study biased signaling and signal transduction pathways involved in alcohol use and anxiety-like behavior using pharmacological and pharmacogenetic tools. The experimental design will cover a wide range of skills and techniques including animal stereotaxic surgery, mouse behavior, neuronal cell culture, immunohistochemistry and Western blotting.
Qualifications: The successful candidate should hold a PhD or MD in pharmacology or neuroscience or related fields. Those candidates with prior experience running rodent behavior assays will be given strong preference as a major component of the work will comprise of animal studies. Additionally, experience working with G protein-coupled receptors, confocal microscopy, adeno- or lentivirus is considered a strength. Candidates must be fluent in spoken and written English, as evident by at least 1 first-author paper. Successful applicants are expected to work as part of a dynamic team, providing training and mentorship when appropriate to graduate and undergraduate students, but also be able to work independently towards manuscripts for publication in peer-reviewed journals.
Interested candidates should submit their application letter, curriculum vitae and a minimum of 2 references that can provide letters of recommendation to rvanrijn@purdue.edu. Salary and benefits follow the NIH standard levels. Applications will be reviewed immediately.
22.3.2018 | Ajankohtaista
Project: Comparison of the biodistribution of viral vectors after intracerebroventricular and hippocampal injections.
Field of study required: Biological or biomedical student
Skills needed from the student: Knowledge of general laboratory techniques and good laboratory practice, including meticulous working methods are anticipated. Motivation and desire to learn new techniques and the ability work independently. Preliminary knowledge of histology is an advantage. We offer the necessary guidance in all laboratory practices.
Duration of the project: 3-4 months (May-August 2018).
Possibility to pay grant: Yes.
Group leader: Academy professor Seppo Ylä-Herttuala
Laboratory: Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, UEF, Kuopio
(The project is part of the Erkko Consortium and it is conducted in collaboration with PhD Francesco Mattia Noé’s Neuro-Lymphatic group.)
More information and applications: Krista Hokkanen (krista.hokkanen@uef.fi) or Taina Vuorio (taina.vuorio@uef.fi)
Description of project:
Viral vectors have been utilized as efficient gene carriers in order to target and deliver therapeutical gene material into specific tissues in the body. In the brain, gene therapy has been used to treat malignant glioma, a devastating brain cancer and has also a great potential in the treatment of other brain pathologies, such as Alzheimer’s and Parkinson’s diseases.
Now we are looking for a motivated student in the biological or biomedical field to help with a project studying the biodistribution of several viral vectors in the brain and peripheral tissues. The viral vectors contain a marker transgene and the expression of the transgene will be followed histologically and with RT qPCR. The tasks of the student include processing, embedding, cutting and immunohistological staining of various mouse tissue samples to identify the transgene expression sites. The expression of the transgene will also be quantified with real time quantitative PCR. We offer the necessary guidance in histological techniques and laboratory practices and we expect from our student a positive and motivated learning attitude.
The Molecular Medicine research group is focused on developing new gene and protein-based approaches for the treatment of cardiovascular diseases. Our research goals also include development of better gene transfer vectors and the identification of new treatment genes for cardiovascular and ischemic diseases. Our group consists of around 10 postdocs, 40 PhD students, 5 laboratory technicians and several students from the fields of biological sciences and medicine. More information: https://www.uef.fi/en/web/aivi/seppo-ylaherttuala-group
20.3.2018 | Ajankohtaista
Individual Fellowships action supports experienced researchers’ mobility between countries and (optionally) to the non-academic sector. IF supports the mobility of researchers within and beyond Europe, as well as aims to attracting the best foreign researchers to work in the EU.
Research funding services Viikki Team will organise an info session on the IF call (open as of 12.4.2018). The session will be held either in Finnish or in English, if applicable.
Time: 23.4.2018 at 13-15
Venue: Korona Information Centre, Viikinkaari 11, 5th floor, meeting room 511
Welcome!
University of Helsinki, Research Funding Services
16.3.2018 | Ajankohtaista
Helsinki Institute of Life Science, HiLIFE, is a new life science institute at the University of Helsinki established in 2017 supporting high quality research across campuses and life science faculties. HiLIFE builds on existing strengths, new recruits and partnerships to create an attractive international environment for solving grand challenges in health, food, and environment. It coordinates research infrastructures in life sciences, provides research-based interdisciplinary training and supports researchers within its units and partner faculties.
Institute of Biotechnology is a part of Helsinki Institute of Life Science, HiLIFE, with a mission to increase knowledge in biotechnology and integrative biology and use this for the benefit of society. Institute of Biotechnology aims to strengthen its position as an international outstanding research institute in biosciences profiled through high impact research and renowned scientists and to develop as an international, competitive and rewarding workplace sought after as a collaboration partner within the university and internationally.
Group Ahtiainen, located in Viikki campus, is looking for outstanding candidates for a position of
Doctoral student, Imaging Cellular Mechanisms of Embryonic Tooth Development
Our group uses a combination of transgenic mouse models and organ culture methods with confocal fluorescence live tissue imaging, cell and molecular biology and transcriptomic approaches to address mechanistic questions in the cell biology of ectodermal organ development and dysplasia. The PhD project will focus on the cell biological aspects of regulation of early tooth development and dysplasia models.
Desired skills and experience: You must hold a M.Sc. degree (or about to graduate) in cell biology, genetics, developmental biology, biochemistry, or related field. Conceptual knowledge of basic cell and molecular biology methods is required and prior practical experience in cell biology or developmental biology is appreciated. Previous experience in imaging or transcriptomics would be an advantage. Since you will be part of an international research environment, good communication skills in English are important.
More information and application at
Deadline for applications is April 15th, 2018.
16.3.2018 | Ajankohtaista
One PhD position is available at the Institute of Biotechnology, University of Helsinki, in the laboratory of Dr. Nicolas Di-Poi (http://www.biocenter.helsinki.fi/bi/di-poi/). Our laboratory is studying the evolution and development (Evo-Devo) of craniofacial structures such as teeth and skull bones in non-classical reptile models. The extraordinary morphological, ecological, and regenerative diversity of reptiles makes them an excellent group to elucidate the developmental processes and pathways that promote lineage diversification and phenotypic variation at different taxonomic levels.
Our research projects include complementary state-of-the-art methods, including molecular embryology, geometric morphometrics, theoretical modeling, genetics, and phylogenomics, and they offer an interdisciplinary environment for research training (see e.g., Nature Communications 9:376 (2018), Science Advances 2:e1600708 (2016), Science 339:78-81 (2013), Nature 464:99-103 (2010)). The exact topic of the research project will be discussed in detail during interview.
The successful Doctoral candidate will have a genuine interest in multidisciplinary research and will hold an excellent Master Degree (or equivalent) in Biology with a specialization in Developmental and/or Evolutionary Biology. In addition, the doctoral candidate will have a strong potential for excellence in research in the above-mentioned research areas.
The Institute of Biotechnology (BI) at the University of Helsinki is an independent research institute with a mission to increase knowledge in biotechnology and integrative biology and use this for the benefit of society. BI has research programs in Molecular Cell Biology, Developmental Biology, Genome Biology, and Structural Biology & Biophysics. BI offers state-of-the-art facilities in imaging, model organisms, proteomics, genomics, bioinformatics, histology, and crystallography. For more information, visit the website: http://www.biocenter.helsinki.fi/bi.
To apply, please send (in a single pdf document) a cover letter describing your previous research and motivation, your detailed CV including a list of publications, as well as contact information for 2 references to Dr Nicolas Di-Poi (nicolas.di-poi@helsinki.fi). The position is expected to start in July 2018 (or as agreed with the selected candidate), and candidates will be considered until the position is filled. Application deadline 31.5.2018.