5.6.2019 | Avoimet työpaikat
https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=1&id=00007430&lang=fi
Senior Research Fellow/Postdoctoral Researcher position is available in the field of Medical microbiology and immunology in the Research Unit of Biomedicine, at the Faculty of Medicine, University of Oulu (http://www.oulu.fi/medicine/ ).
Research Environment
The University of Oulu in Northern Finland, with approximately 16,000 students and 3,000 employees, is an international, multidisciplinary research university with a rich pool of creative and intellectual talent. The strengths of the University include broad, multidisciplinary research interests, a modern research and study environment, and wide cooperation with international research and educational institutes (http://www.oulu.fi/university/ ).
Subject field and description of the position
The research field for the position will be medical microbiology and immunology. The duration of the position is for 5 years. The starting date is August 1, 2019, or as soon as possible thereafter. A six-month trial period will be effective in the beginning of the 5-year contract.
The successful applicant must hold a PhD degree in biomedicine, or related discipline.
Fluency in both written and spoken English, experience in writing scientific publications, teaching experience as well as good communication and teamwork skills are required. Activity in the scientific community, supervision experience, ability to participate teaching preferably in Finnish and potential in acquiring supplementary funding will be taken as merits.
Furthermore, an applicant for the Senior Research Fellow position should have postdoctoral experience in the relevant research field (preferably including mobility) and demonstrated ability for research supervision and acquiring supplementary funding. As part, the duties also include supervising scientific research of BSc, MSc, and PhD students. Participation in teaching in medical microbiology and immunology, and in acquiring research funding are expected.
Salary
The salary will be based on level 6 or 7 (Senior Research Fellow) or level 5 (Postdoctoral Researcher) of the demand level chart for university-level teaching and research staff of Finnish universities. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component).
Application Procedure
The following documents must be attached to the application (in English):
1) Curriculum vitae
2) List of publications
3) Brief description of research merits and experience
4) Description of teaching merits
5) Contact information of two persons who may be asked to give a statement of the candidate
Applications, together with all relevant enclosures, must be submitted using the electronic application system form by June 9th, 2019.
Applications sent by email will not be considered.
More information
Professor Timo Hautala
timo.hautala@oulu.fi
5.6.2019 | Avoimet työpaikat
Doctoral (PhD) student position in Reproductive Toxicology at Karolinska Institutet
We
are recruiting a doctoral (PhD) student. For more information regarding
doctoral education at Karolinska Institutet (KI), see: http://ki.se/en/phd/about-doctoral-education-at-ki
A
doctoral student is admitted to third-cycle/doctoral education. A
doctoral education consists of supervised research, combined with
courses and other educational activities.
An individual study plan is established for each doctoral student. For a
doctoral degree, the equivalent of four years of full-time doctoral
education is required.
Research group
The doctoral education project will be
carried out in Associate Professor Pauliina Damdimopoulou’s research
laboratory at the Division of Obstetrics and Gynecology at the
Department of Clinical Science, Intervention and Technology
of Karolinska Institutet. Research and education at the Division of
Obstetrics and Gynecology are focused on the many aspects of women’s
reproductive health as well as fetal physiology and stem cell biology.
Damdimopoulou
laboratory is located at the Campus Flemingsberg of Karolinska
Institutet and focuses on human ovarian biology as well as effects of
toxic chemicals on fertility.
The doctoral student project and the duties of the doctoral student
The doctoral education project will be carried out within the Horizon2020 project FREIA (http://www.freiaproject.eu/
), which rises from a concern that environmental factors can affect a
woman’s chances of becoming pregnant. Hence, the ambition of FREIA is to
develop novel identification and screening approaches for endocrine
disrupting chemicals (EDCs) that target female
fertility. The aim of this doctoral education project is to study the
effects of EDCs on human ovarian follicle growth in vitro and identify
associated adverse outcome pathways. Cross-species validation will be
carried out by comparing the findings to rat studies
carried out in FREIA. In addition, ovarian transcriptomics datasets will
be used to understand possible age-dependent differences in chemical
toxicity. The work will require visits to laboratories of co-supervisors
in Finland, Denmark and Estonia.
The
duties of the doctoral student include cell and tissue culture, gene
expression analyses and histological analyses. In addition, the student
will assist in collection
and analyses of rat ovaries and oocytes. The project also involves
analyses of RNA-seq datasets. Techniques utilized will include in vitro
culture of human ovarian tissue samples, isolation and culture of
primary ovarian cells, immunostaining, fluorescent microscopy
and histomorphometric analyses, as well as bioinformatics analyses in R.
More information and application at https://ki.mynetworkglobal.com/en/what:job/jobID:273819/?fbclid=IwAR2OXCXXaosNq1LSndOxsCftVXdwRSN5XgMqookT60uHSWbm2uqup52GSfs
Last application date is June 20, 2019 11:59 PM CET.
5.6.2019 | Avoimet työpaikat
The
immuno-oncology research team coordinated by Dr Jeroen Pouwels at the
University of Helsinki Faculty of Medicine is looking to hire an
ambitious
Postdoc in Translational Immuno-Oncology
The candidate
will join a collaborative immuno-oncology project funded by an Academy
of Finland project grant of Dr Jeroen Pouwels that seeks new ways to
sensitize breast cancer to immune checkpoint
inhibitors. The very translational research group is part of the
Translational Cancer Medicine Research Program of the Medical Faculty’s
Research Programs Unit (RPU) and is aligned with the Finnish Flagship
Programme iCAN. A novel method to grow 3D cultures
of intact fragments of patient-derived tissue (Patient-Derived Explant
Cultures), which preserves the human tumor microenvironment including
the immune-contexture, reflects inter- and intra-patient tumor
heterogeneity and, importantly, can assess the efficacy
of novel treatment regimens on real human tumors (Haikala et al., Nature
Comm. 2019; PMID: 30728358), will play a central role in the project.
For more information and to apply, please visit https://www.helsinki.fi/en/open-positions/postdoc-in-translational-immuno-oncology
Deadline for applications is August 5, 2019.
3.6.2019 | Avoimet työpaikat
https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=2&id=00007374&lang=fi&fbclid=IwAR1FLy4RK6TWre_YIKKqycxx4ZM4CZk3E5mZJayrrTf3_sW8u_vn5hTACr4
Jyväskylän keskustassa sijaitsevan yliopiston kauniilla
puistokampuksella sykkii monitieteinen ja moderni tiedeyliopisto –
ihmisläheinen ja dynaaminen yhteisö, jonka 2 500 asiantuntijaa ja 15 000
opiskelijaa etsivät ja löytävät vastauksia huomisen kysymyksiin.
Jyväskylän yliopisto on ollut tulevaisuuden palveluksessa jo vuodesta
1863, jolloin suomenkielinen opettajankoulutus sai alkunsa täältä.
Voimanlähteenämme on moniarvoinen vuoropuhelu tutkimuksen, koulutuksen
ja yhteiskunnan välillä. Vaalimme tutkimuksen ja koulutuksen tasapainoa
sekä ajattelun avoimuutta – sytytämme taidon, tiedon ja intohimon elää
viisaasti ihmiskunnan parhaaksi.
Haettavana on
erikoislaboratoriomestarin tehtävä 1.8.2019 alkaen toistaiseksi.
Liikuntatieteiden koulutus ja tutkimus on keskitetty maassamme
Jyväskylän yliopiston liikuntatieteelliseen tiedekuntaan. Liikuntaa ja
terveyttä, niiden välisiä yhteyksiä sekä liikunnan ja terveyden
edistämistä tarkastellaan monitieteisesti, päämääränä terveyden,
toimintakyvyn ja hyvinvoinnin lisääminen elämänkulun eri vaiheissa.
Tiedekunnan valtakunnallisiin tehtäviin kuuluu keskeisesti liikunnan-
ja terveystiedon sekä terveystieteiden (fysioterapia)
opettajankoulutus. Tiedekunnassa on liikuntatieteiden ja
terveystieteiden koulutusalat. Tiedekunnassa on kolme tieteenalaryhmää:
liikuntabiologia, liikunnan käyttäytymis-yhteiskuntatieteet
ja terveystieteet. Tiedekunnassa toimii kolme tutkimuskeskusta:
Neuromuscular Research Center, Gerontologian tutkimuskeskus sekä
Terveyden edistämisen tutkimuskeskus.
Erikoislaboratoriomestarin tehtävä sijoittuu liikuntatieteellisen
tiedekunnan 10-henkiseen laboratoriotiimiin erityisesti bioanalytiikan
osa-alueelle. Erikoislaboratoriomestari tuottaa analyysejä ja kehittää
analyysimenetelmiä liikuntatieteellisen tiedekunnan eri tutkimusryhmien
tarpeisiin. Erikoislaboratoriomestarin tehtävässä painottuvat
ensisijaisesti verinäytteiden ottaminen ja käsittely sekä
nukleiinihappo- ja proteiinitason analyysit veri-, kudos- että
soluviljelynäytteistä. Lisäksi tehtävään sisältyy laboratorion
välinehuoltoon ja yleiseen ylläpitoon kuuluvia tehtäviä yhteistyössä
muun laboratoriohenkilöstön kanssa. Erikoislaboratoriomestarin
työtehtäviin kuuluu myös laboratoriossa työskentelevien tutkijoiden ja
opiskelijoiden (kandidaatti-, maisteri- ja tohtoriopiskelijat)
avustamista, neuvontaa ja ohjausta.
Hakijalta edellytetään bioanalyytikon (AMK tai YAMK) tai vastaavaa
koulutusta. Hakijan osaamisalueena tulee olla biokemian, solu- ja
molekyylibiologian ja genetiikan menetelmät, sekä kokemusta ja näyttöä
näiden menetelmien käytännön hallinnasta. Eduksi luetaan kokemus
erilaisiin kliinisiin kuormituskokeisiin liittyvistä tehtävistä sekä
asiantuntemus solu- ja molekyylibiologisista menetelmistä. Tehtävässä
odotetaan myös valmiutta/kyvykkyyttä menetelmien kehittämisessä ja
soveltamisessa liikuntatieteelliseen tutkimukseen. Tehtävän
menestyksellistä hoitamista edesauttavat hyvä englannin kielen taito,
kyky sekä itsenäiseen työskentelyyn että tiimityöhön ja analyyttinen
sekä kriittinen oman työn arviointi ja kehittäminen.
Laboratoriomestarin tehtäväkohtainen palkanosa määräytyy yliopistojen
palkkausjärjestelmän muun henkilöstön tehtävien vaativuustason 6 (2
092,99 €/kk) perusteella. Lisäksi maksetaan henkilökohtaiseen työstä
suoriutumiseen perustuvaa palkanosaa 6-50 % tehtäväkohtaisesta
palkanosasta.
Tehtävää täytettäessä käytetään kuuden kuukauden koeaikaa.
Lisätietoja: akatemiatutkija Eija Laakkonen, eija.k.laakkonen@jyu.fi, puh. +358408053588.
Sähköiseen hakulomakkeeseen tulee liittää:
1) Hakemus
2) Ansioluettelo (cv)
3) Muu liite, jolla hakija haluaa osoittaa kelpoisuutensa ja ansionsa tehtävään.
Hakemus tulee jättää viimeistään 6.6.2019 sähköisellä hakulomakkeella.
3.6.2019 | Avoimet työpaikat
https://rekry.saima.fi/certiahome/open_job_view.html?did=5600&jc=2&id=00007391&lang=fi&fbclid=IwAR0Jz5Db0XeisdcSl3vpwgn_qY1PF2024DmkEkpVu3m6jdAYcBSvthTpNjI
Jyväskylän keskustassa sijaitsevan yliopiston kauniilla
puistokampuksella sykkii monitieteinen ja moderni tiedeyliopisto –
ihmisläheinen ja dynaaminen yhteisö, jonka 2 500 asiantuntijaa ja 15 000
opiskelijaa etsivät ja löytävät vastauksia huomisen kysymyksiin.
Jyväskylän yliopisto on ollut tulevaisuuden palveluksessa jo vuodesta
1863, jolloin suomenkielinen opettajankoulutus sai alkunsa täältä.
Voimanlähteenämme on moniarvoinen vuoropuhelu tutkimuksen, koulutuksen
ja yhteiskunnan välillä. Vaalimme tutkimuksen ja koulutuksen tasapainoa
sekä ajattelun avoimuutta – sytytämme taidon, tiedon ja intohimon elää
viisaasti ihmiskunnan parhaaksi.
Haettavana on
erikoislaboratoriomestarin tehtävä 1.8.2019 alkaen toistaiseksi.
Liikuntatieteiden koulutus ja tutkimus on keskitetty maassamme
Jyväskylän yliopiston liikuntatieteelliseen tiedekuntaan. Liikuntaa ja
terveyttä, niiden välisiä yhteyksiä sekä liikunnan ja terveyden
edistämistä tarkastellaan monitieteisesti, päämääränä terveyden,
toimintakyvyn ja hyvinvoinnin lisääminen elämänkulun eri vaiheissa.
Tiedekunnan valtakunnallisiin tehtäviin kuuluu keskeisesti liikunnan-
ja terveystiedon sekä terveystieteiden (fysioterapia)
opettajankoulutus. Tiedekunnassa on liikuntatieteiden ja
terveystieteiden koulutusalat. Tiedekunnassa on kolme tieteenalaryhmää:
liikuntabiologia, liikunnan käyttäytymis-yhteiskuntatieteet
ja terveystieteet. Tiedekunnassa toimii kolme tutkimuskeskusta:
Neuromuscular Research Center, Gerontologian tutkimuskeskus sekä
Terveyden edistämisen tutkimuskeskus.
Erikoislaboratoriomestarin tehtävä sijoittuu liikuntatieteellisen
tiedekunnan 10-henkiseen laboratoriotiimiin. Erikoislaboratoriomestarin
tehtävänä on hallinnoida laboratorioympäristön tila- ja
laitevarausjärjestelmää, koordinoida tutkimusprojektien ja opetuksen
tarpeita sekä avustaa pienhankintojen ja laitehankintojen tekemisessä.
Erikoislaboratoriomestari osallistuu myös suoritus- ja
toimintakykylaboratoriossa toteutettavien tutkimusten mittauksiin ja
tuottaa niistä perusanalyyseja sekä muutoin avustaa tutkimusten
toteuttamisessa. Lisäksi tehtävään voi sisältyä mittauslaitteiden
kunnossapitoa ja kehittämistä yhteistyössä teknisen pajan henkilöstön
kanssa. Erikoislaboratoriomestarin työtehtäviin kuuluu myös
laboratoriossa työskentelevien tutkijoiden ja opiskelijoiden
(kandidaatti-, maisteri- ja tohtoriopiskelijat) avustamista, neuvontaa
ja ohjausta.
Hakijalta edellytetään soveltuvaa AMK tai yliopistotutkintoa tai
vastaavaa koulutusta. Hakijalta edellytetään osaamista ja työkokemusta
projektikoordinaatiosta sekä ICT-taitoja. Eduksi katsotaan aikaisempi
kokemus laboratoriossa työskentelystä, signaalinkäsittelytaidot ja
tiedonhallintataidot. Tehtävän menestyksellistä hoitamista edesauttavat
hyvä englannin kielen taito, kyky sekä itsenäiseen työskentelyyn että
tiimityöhön ja analyyttinen sekä kriittinen oman työn arviointi ja
kehittäminen.
Laboratoriomestarin tehtäväkohtainen palkanosa määräytyy yliopistojen
palkkausjärjestelmän muun henkilöstön tehtävien vaativuustason 6 (2
092,99 €/kk) perusteella. Lisäksi maksetaan henkilökohtaiseen työstä
suoriutumiseen perustuvaa palkanosaa 6-50 % tehtäväkohtaisesta
palkanosasta.
Tehtävää täytettäessä käytetään kuuden kuukauden koeaikaa.
Lisätietoja: apulaisprofessori Neil Cronin, neil.j.cronin@jyu.fi, puh.+358408053735.
Sähköiseen hakulomakkeeseen tulee liittää:
1) Hakemus
2) Ansioluettelo (cv)
3) Muu liite, jolla hakija haluaa osoittaa kelpoisuutensa ja ansionsa tehtävään.
Hakemus tulee jättää viimeistään 6.6.2019 sähköisellä hakulomakkeella.
30.5.2019 | Avoimet työpaikat
https://jobs.criver.com/job/Kuopio-Biomarker-Scientist-IS-70210/561750400/?fbclid=IwAR2IkZmDakFrPjQYju0wBoDyHbpJ1gMfU7962YmiQmpw1NN-U3oALq8Ohqk
Biomarker Scientist
Req ID #:
44673
Location:
Kuopio, IS, FI, 70210
For
over 70 years, Charles River employees have worked together to assist
in the discovery, development and safe manufacture of new drug
therapies. When you join our family, you will have a significant impact
on the health and well-being of people across the globe. Whether your
background is in life sciences, finance, IT, sales or another area, your
skills will play an important role in the work we perform. In return,
we’ll help you build a career that you can feel passionate about.
Scientist, Neuroimmunology and immunohistochemistry
We are looking for a scientist with proven track of experience in ex vivo molecular and cellular neuroscience.
The
position requires expertise in immunology and immunohistochemistry in
basic science and preferably drug discovery using preclinical models of
CNS.
In
this position you will be independently leading projects focusing to
relevant ex vivo endpoints of efficacy in animal models, including e.g.
PD, AD, MS and injury-triggered animal models.
You
have a strong expertise in various types of ex vivo analysis and
interpretation of biomarkers derived from preclinical in vivo models.
You have strong background e.g. in multiparameter flow cytometry,
immunohistochemistry, cytokine profiling, supporting immune function
assessment.
You
are independently able to manage planning, coordination, supervision
and execution of the ex vivo part of client projects and ensuring the
scientific excellence including data analysis and reporting of the
results. Scientist will be working closely with other teams and clients.
In addition to client projects, scientist will be involved R&D
activities including validations of new markers and assays to support ex
vivo readouts.
Qualifications and Experience:
- Higher education degree in biological science (MSc) with 3+ years of experience, preferably PhD degree
- Pharmaceutical industry, Preclinical Contract Research Organization or academic post-doctoral experience will be an asset.
- Good problem solving skills, ability to coordinate and prioritize
- Scientific expertise with demonstrable understanding of ex vivo techniques and neuroimmunology as a component in CNS diseases
- Understanding of key features of in vivo pharmacology studies and drug development process in neurology and psychiatry
- Hands on experience in development, optimization and validation of immunohistochemistry targets in CNS tissues
- Hands
on experience in development, optimization and validation of
multi-color flow cytometry, data analysis and troubleshooting using
multiparametric data analysis
- Experience
in other immunological techniques like in vitro cell cultures, Luminex,
ELISA, gene expression analysis (qPCR, QuantiGene Plex) will be an
asset
- Fluent oral and written English, excellent communication skills, interpersonal and teamwork abilities
- Ability to mentor and train staff will be an asset
About Discovery
Discovery from Charles River is
industry-proven in the successful development of novel therapies, with
over 320 patents and 74 preclinical drug candidates delivered to our
sponsors in the past 17 years. Backed by more than 650 scientists, our
comprehensive, integrated portfolio employs the latest technology and
platforms to provide chemistry, biology, and pharmacology services that
support clients from the earliest stages of hit identification all the
way through to IND. Our client-focused, collaborative approach creates
true partnerships that anticipate challenges, overcome obstacles, and
move us forward together on the journey of getting new drugs to market.
About Charles River
Charles River is an early-stage
contract research organization (CRO). We have built upon our foundation
of laboratory animal medicine and science to develop a diverse portfolio
of discovery and safety assessment services, both Good Laboratory
Practice (GLP) and non-GLP, to support clients from target
identification through preclinical development. Charles River also
provides a suite of products and services to support our clients’
clinical laboratory testing needs and manufacturing
activities. Utilizing this broad portfolio of products and services
enables our clients to create a more flexible drug development model,
which reduces their costs, enhances their productivity and effectiveness
to increase speed to market.
With
over 11,000 employees within 70 facilities in 18 countries around the
globe, we are strategically positioned to coordinate worldwide resources
and apply multidisciplinary perspectives in resolving our client’s
unique challenges. Our client base includes global pharmaceutical
companies, biotechnology companies, government agencies and hospitals
and academic institutions around the world. And in 2016, revenue
increased by 23.3% to $1.68 billion from $1.36 billion in 2015.
At Charles River, we are passionate
about our role in improving the quality of people’s lives. Our mission,
our excellent science and our strong sense of purpose guide us in all
that we do, and we approach each day with the knowledge that our work
helps to improve the health and well-being of many across the globe. We
have proudly supported the development of ~70% of the drugs approved by
the FDA in 2016.
For more information, please visit www.criver.com.
Job Segment:
Chemistry, Scientific, Biotech, Scientist, Telecom, Science, Engineering, Technology
27.5.2019 | Avoimet työpaikat
PhD project in inflammation and infections group
PhD
project is available in the research group led by Dr. Karita Haapasalo
at the Department of Bacteriology and Immunology, Haartman Institute. We
are looking for an ambitious and enthusiastic
MSc of MD with a research interest in immunology and inflammatory
diseases. The project is suitable for a applicant with a knowledge of
immunology, microbiology, biochemistry, cell biology or other relevant
field. After a four months trial period there is an
opportunity to continue the project and apply for PhD studentship.
To
apply, please send a CV including course evaluation records and
Master’s diploma, a short cover letter explaining motivation to
scientific research and names and contact details
of at least two referees as one single document to karita.haapasalo@helsinki.fi. Applications will be accepted until the position is filled.
See more information here: https://www.helsinki.fi/en/researchgroups/inflammation-and-infections
27.5.2019 | Avoimet työpaikat
Postdoctoral position(s) available in autumn 2019 at the University of Helsinki
Our
lab studies mitochondrial morphogenesis and dynamics. More
specifically, we focus on the molecular mechanism of mitochondrial
membrane architectural organization and factors involved in regulation
of mitochondrial shape, dynamics, and their functional link to
mitochondrial diseases.
We
are looking for highly motivated individual(s) with a strong background
in cell biology/mitochondrial biology, and biochemistry.
For more information, please refer to the relevant publication:
Wang L, Yan Z, Vihinen H, Eriksson O, Wang W, Soliymani R, Lu Y, Xue Y, Jokitalo E, Li J, Zhao H* (2018) FAM92A1 Is a BAR Domain
Protein Required for Mitochondrial Ultrastructure and Function. J. Cell Biol. 218:97-111.
Please
send a cover letter with short description of your research interests
and previous experience, current CV, and names of three
references to Hongxia.zhao@helsinki.fi .
26.5.2019 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/1279827721/?refId=ff6009b5-3f49-4aed-8fab-1c1828bdd5c9&trk=eml-vjr-similar-job-title&midToken=AQFgumZyIt6sOQ&trkEmail=eml-email_jobs_viewed_job_reminder_01-null-27-null-null-41f64x%7Ejw2a9jpo%7Emq-null-jobs%7Eview
Orion Corporation is a globally operating Finnish
pharmaceutical company – a builder of well-being. Orion develops,
manufactures and markets human and veterinary pharmaceuticals and active
pharmaceutical ingredients.
Description of position
We are building up the Rare Diseases Therapy Area and
are looking for an enthusiastic and innovative scientist who can
contribute with strong disease biology knowledge in the field of rare
genetic disorders (or neurodegerative disorders). Your main
responsibilities will be to:
- Actively contribute to project ideation, planning and execution of research activities.
- Provide expertise in molecular biology and drug mechanism of action.
- Perform
hands-on laboratory work related to transcription and translation of
e.g. lysosomal and mitochondrial proteins as well as to cell signaling
pathways, and how these can be targeted and modified.
- Analyse and interpret data and effectively document and communicate results.
- Interface with external academic, biotechnology, and contract research organizations.
Description of the unit
The focus of our Rare Diseases Therapy Area is on
progressive, serious and life-threatening diseases, where patients are
lacking adequate treatment. We aim to develop treatments which are
disease modifying or which deliver significant symptomatic relief to
patients. To fulfill this exciting task the Rare Diseases Therapy area
is strengthened by recruiting new R&D experts to our team in Turku.
The therapy area is newly established and you have a great opportunity
to be part of developing our processes.Therapy area of the Central
Nervous System (CNS) is accountable for the research and development of
medications for neurodegenerative diseases (NDD).
We offer
We offer exciting opportunities to create and have an impact to the future therapies for patients.
In Orion we have a highly interesting R&D pipeline and
enthusiastic working environment with opportunities to use your own
strengths to build your competence development and career. As an expert
of your own field you will be a member of multi-disciplinary team
jointly innovating and developing new treatments for the patients.
Appreciation of colleagues and continuous development are part of our
core values. The culture of Orion R&D is informal and we enjoy
working together.
We are passionate about the patient welfare and serve as The
Voice of Science and the Patient – if this inspires you too – join us!
Requirements
- Ph.D. degree in cell and/or molecular biology with at least 3 years postdoc experience.
- Hands-on
experience with molecular biology techniques such as qPCR, WB, siRNA,
CRISPR/Cas9 as well as immunodetection techniques.
- Expertise in cell signaling.
- Expertise in rare genetic disorders or neurodegenerative diseases research.
- Understanding of drug discovery and development.
Contact information
Would you like to know more about the position? Please
contact Harry Björklund, Research Director Rare Diseases, +358509667436.
He is best available during the following times (EEST): Monday 20th of
May 14.00 – 16.00, Wednesday 22nd of May 9.00 – 11.00 and Tuesday 28th
of May 14.00 – 16.00. Please send your application latest on 2 June
2019.
Orion Corporation operates in more than 25 countries, where we
Orionees, 3200 in total, work in all kinds of positions. We encourage
people to develop their competences, and offer opportunities to affect
own job description and create own career path at Orion.
26.5.2019 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/1263547935/?refId=ff6009b5-3f49-4aed-8fab-1c1828bdd5c9&trk=eml-vjr-similar-job-apply&midToken=AQFgumZyIt6sOQ&trkEmail=eml-email_jobs_viewed_job_reminder_01-null-9-null-null-41f64x%7Ejw2a9jpo%7Emq-null-jobs%7Eview
Orion Corporation is a globally operating Finnish
pharmaceutical company – a builder of well-being. Orion develops,
manufactures and markets human and veterinary pharmaceuticals and active
pharmaceutical ingredients.
Description of position
As a member of the newly established Biologics and New
modalities Discovery Groups you will work closely with cross-functional
teams to provide computational biology support to the antibody and new
modalities discovery process. Your primary responsibilities will include
the application of structural analysis to sequences from both internal
and public databases to enable therapeutic protein design,
oligonucleotide designs, gene editing designs, CRISPR-based gene
editing, and antibody repertoire analysis.
The identification of relevant liabilities in nucleotide
sequences will be a critical responsibility in order to successfully
support generation and optimization of the modalities (therapeutic
oligonucleotide, peptides and biologics). You support day to day
laboratory work in-house and you will therefore have a good possibility
to do a lot of hands-on laboratory work verifying the computational
designs. You will be also the primary contact with collaborations with
partners and CROs on your expertise areas. You will be based in Turku.
We offer
Exciting opportunities to create and have an impact to the future therapies for patients.
In
Orion we have a highly interesting R&D pipeline and enthusiastic
working environment with opportunities to use your own strengths to
build your competence development and career. As an expert of your own
field you will be a member of multi-disciplinary team jointly innovating
and developing new treatments for the patients. Appreciation of
colleagues and continuous development are part of our core values. The
culture of Orion R&D is informal and we enjoy working together.
We are passionate about the patient welfare and serve as The
Voice of Science and the Patient – if this inspires you too – join us!
Description of the unit
Orion’s pharmaceutical innovations are created within
its R&D organization, including e.g. non-clinical research, clinical
development, formulation development and medical affairs. The
organization employs top professionals in the field of drug molecule
development and optimization.
The newly established Biologics and New Modalities team is part
of our R&D organization and it is responsible for bringing as new
treatment modalities for Orion’s pipeline covering therapeutic
nucleotides, delivery technologies and gene therapy. Adding the
possibility to modulate the target with either small or large molecules
enables us to choose the right target and then use the best modalities
to modulate the target protein in order to create the best value for
patients. To fulfill this exciting task the New Modalities function is
strengthened by recruiting new R&D experts with a track record of on
advanced therapy modalities. The function is currently to set up and
you have a great opportunity to be part of developing our processes.
Requirements
To operate successfully in this position you should
have a PhD degree in genetics, molecular biology, computational or
biology structural biology with several years of post-doctoral
experience in computational biology to support optimization of
therapeutic large molecules. You should also have thorough understanding
of in vitro models for system biology and biophysical data analysis.
Willingness to create new things is a must because you will
join a team that is just recently set up. The role includes
collaboration within Orion and with various collaborators, therefore
strong communication skills and an ability to convince your audience is
an asset.
Contact information
Would you like to know more about the position? Please
contact Jyrki Lehtimäki, Senior Manager, Strategic Development,
+358509667478. He is best available during the following times (Finnish
times): 17th and 24th May 15.00-17.00 pm. Please send your application
latest on 2 June 2019.