26.4.2017 | Ajankohtaista
Training Network to Understand and Exploit Mechanisms of Sensory Perception in Bacteria
Located in Ireland, Germany, Netherlands, Spain, Sweden, Switzerland and UK
Project background and goal: The PATHSENSE (Pathogen Sensing) ETN investigates the molecular mechanisms of sensory perception in bacterial pathogens. Rapid and sensitive systems to sense and respond to environmental changes are a cornerstone of a bacterium’s survival apparatus, and understanding these sensory systems is central to predicting their behaviour. The success of bacterial pathogens is underpinned by their ability to sense their environment in order to protect themselves and then to deploy their virulence mechanisms at the appropriate time. A deep knowledge of how their first line of defence (sensory perception) functions is a vital step in developing strategies to subvert their survival apparatus, and ultimately to preventing human, animal and plant infections.
The overall objective of this project is to focus on understanding a highly sophisticated but poorly understood sensory organelle called the “stressosome”. The relationship between molecular structures and biological function is central to understanding any living system; however the research methodologies required to unravel these relationships are often complex and fast-changing. The team participating in the PATHSENSE Network will recruit and train 13 early stage researchers (ESRs) in state-of-the art methodologies, including structural biology, proteomics & protein biochemistry, molecular biology, bacterial genetics, food microbiology, mathematical modelling, cell biology, microscopy and comparative genomics. This inter-sectoral Network comprises 8 leading Universities, 1 public research institution, 4 companies (from spin-off to large multi-national) and 1 governmental agency. A major objective of this Network will be to exploit the fundamental research to develop novel antimicrobial treatments that have applications in the food and public health sectors.
To apply and for further details on these opportunities see:
Closing date for receipt of applications is 5pm (GMT) on Friday 12th May 2017.
26.4.2017 | Ajankohtaista
The University of Oulu in Northern Finland, with approximately 16,000 students and 3,000 employees, is an international, multidisciplinary research university with a rich pool of creative and intellectual talent. The strengths of the University include broad, multidisciplinary research interests, a modern research and study environment, and wide cooperation with international research and educational institutes (http://www.oulu.fi/university/).
An open postdoctoral position is available in the field of structural biology in the research group of Prof. Petri Kursula, focusing on membrane protein structural biology and the formation of proteolipid membrane multilayers in the nervous system myelin sheath. The position is located at the Faculty of Biochemistry and Molecular Medicine (FBMM) (http://www.oulu.fi/fbmm/), whose mission is to perform internationally significant research and to deliver high-level undergraduate and postgraduate education in the fields of biochemistry and molecular medicine. Research at the Faculty is carried out in 14 research groups. The Faculty has ~200 employees, and approximately half of them are from abroad. Together with Biocenter Oulu (http://www.oulu.fi/biocenter/), the Faculty has put a great effort towards building a cutting-edge research infrastructure that includes state-of-the-art instrumentation for imaging, gene-modified mice, X-ray crystallography, and quantitative biochemistry. The Faculty has extensive collaborative national and international networks including Biocenter Finland and the ESFRI projects Instruct, EuroBioimaging, and Infrafrontier. We also partner in EU-Biostruct-X and Marie Curie Renaltract ITN and organize EMBO workshops and international symposia. The research group has well-established international collaborative networks and frequent access to synchrotron radiation.
Applications, together with all relevant enclosures, must be submitted using the electronic application form by 15.5.2017. Applications sent by email will not be considered.
11.4.2017 | Ajankohtaista
We are seeking a highly experienced biocurator to become a faculty level Team Leader for the Protein Function Content Team at the European Bioinformatics Institute (EMBL-EBI), located on the Wellcome Genome Campus, near Cambridge, in the UK. The Protein Function Content Team Leader manages a team of expert biologists in manual curation of proteins as part of the international UniProt (http://www.uniprot.org ) and GO (http://www.geneontology.org) consortia, as well as other related data resources.
Deadline for applications is 17.4.2017.
10.4.2017 | Ajankohtaista
Description:
Applications are invited from suitably qualified candidates for a full-time PhD position at the National University of Ireland, Galway. The position is funded from Teagasc (ReValueProtein
Research Project) and the Department of Agriculture, Food and the Marine, under the National Development Plan 2007–2013 of the Irish Government. The position is available immediately. Stipend (€16,000 per year) and EU fees are covered from the grant. The project aims to develop and assess in vitro and in vivo drug / gene loaded biomaterials.
Recruiting Institute:
REMODEL: http://remodel.ie
SFI CÚRAM: http://www.curamdevices.ie
NUI Galway: http://www.nuigalway.ie
Qualifications:
The candidate should have a 1st class or a 2:1 honours first degree and a Master’s in biomaterials, biomedical engineering, tissue engineering, medicine, cell biology, biology, drug discovery or in a related area. The ideal candidate should have experience in as many of the following techniques: scaffold fabrication, functionalisation and characterisation; cell (permanently differentiated and stem cells) biology; molecular biology; protein / gene analysis; histology; and immunohistochemistry. Candidates should have excellent communication and organisational skills; be highly motivated and passionate about developing new products; and have strong written, oral and interpersonal skills. The candidate should be able to work independent and as a part of team.
Duties:
Scaffold fabrication, functionalisation, and characterisation; Cell acquisition from human and animal tissues; In vitro models; In vitro and in vivo work; Conference / Meeting attendance; Report / paper writing; Attendance to various training courses; Other duties relevant to the post.
Start Date:
The post is available from May 2017 onwards.
To Apply:
Applicants should submit a cover letter outlining their suitability to the post, a detailed CV and the contact details of three referees. The application pack should be emailed to Dr Dimitrios Zeugolis at dimitrios.zeugolis@nuigalway.ie. Closing date for receipt of applications is 17.00 on Friday 28th of April 2017.
Equal Opportunities Statement:
The National University of Ireland Galway is an equal opportunities employer.
10.4.2017 | Ajankohtaista
www.finbionet.fi/PhD_Fellowship%20_NUI_Galway.pdf
Description:
Applications are invited from suitably qualified candidates for a full-time PhD position at the National University of Ireland, Galway. The position is funded from Science Foundation Ireland
(Tissue Engineered Nanoassemblies of Advanced Biomimicry of Living Equivalents Projects). The position is available immediately. Stipend (€16,000 per year) and EU fees are covered from the grant. The project aims to develop cell therapies based on induced pluripotent stem cells.
Recruiting Institute:
REMODEL: http://remodel.ie
SFI CÚRAM: http://www.curamdevices.ie
NUI Galway: http://www.nuigalway.ie
Qualifications:
The candidate should have a 1st class or a 2:1 honours first degree and a Master’s in cell biology, tissue engineering, biomedical engineering, medicine, biology, or in a related area. The ideal candidate should have experience in as many of the following techniques: in vitro culture systems (e.g. 3D culture; bioreactors); cell (permanently differentiated, stem cells, engineered cells) biology; molecular biology; protein / gene analysis; histology; and immunohistochemistry. Candidates should have excellent communication and organisational skills; be highly motivated and passionate about developing new products; and have strong written, oral and interpersonal skills. The candidate should be able to work independent and as a part of team.
Duties:
Cell acquisition from human and animal tissues; In vitro / ex vivo cell / organ culture; development of advanced therapy medicinal products; In vivo work; Conference / Meeting attendance; Report / paper writing; Attendance to various training courses; Other duties relevant to the post.
Start Date:
The post is available from May 2017 onwards.
To Apply:
Applicants should submit a cover letter outlining their suitability to the post, a detailed CV and the contact details of three referees. The application pack should be emailed to Dr Dimitrios Zeugolis at dimitrios.zeugolis@nuigalway.ie. Closing date for receipt of applications is 17.00 on Friday 28th of April 2017.
Equal Opportunities Statement:
The National University of Ireland Galway is an equal opportunities employer.
16.3.2017 | Ajankohtaista
POSTDOCTORAL RESEARCH FELLOW
The Department of Anesthesiology and Washington University Pain Center seeks a Postdoctoral Research Fellow for a trained behavioral pharmacologist and biochemist/molecular biologist to study mechanisms underlying opioid dependence and to examine the interaction between pain and opioid misuse (see Fakira et al., 2014 Biological Psychiatry; Portugal et al., 2014 Journal of Neuroscience; Hipolito et al., 2015 Journal of Neuroscience; Fakira et al., 2016 Neuropsychopharmacology). The laboratory integrates the study of the molecular and cellular changes induced by drugs of abuse using a combination of state-of-art behavioral, optogenetics, chemogenetics approaches in combination with electrophysiological analyses. For more details see lab web page (http://elysium.wustl.edu/moron-concepcion_lab/)
Candidates must have a PhD in neuroscience, biochemistry, pharmacology or biomedical sciences. Experience with behavioral pharmacology expertise, opto/chemogenetics, molecular biology, biochemical techniques is required. The successful candidate should be able to work independently and be willing to collaborate with the groups of Dr Rob Gereau and Michael Bruchas at the Department of Anesthesiology.
Interested candidates should also forward their CV and names of 3 references to:
Jose A. Morón Concepción, PhD
Associate Professor
Depts of Anesthesiology & Neuroscience
Washington University School of Medicine
16.3.2017 | Ajankohtaista
Postdoctoral Position: Mechanisms of synaptodendritic injury in opiate abuse and HIV comorbidity
A postdoctoral position is available immediately at the Virginia Commonwealth University (VCU) School of Medicine to study fundamental mechanisms underlying glial dysfunction and synaptodendritic injury in the striatum and hippocampus following drug and HIV exposure.
The candidate will utilize and integrate cellular and molecular approaches to elucidate mechanisms by which opiate abuse exacerbates glial dysfunction and synaptodendritic injury in neuro-acquired immunodeficiency syndrome (neuroAIDS). A Ph.D. and/or M.D. or equivalent is required, and experience in molecular and/or virological approaches is preferred. The candidate will join a team that utilizes multi-disciplinary cell signaling, pharmacological, immunological, neurophysiological (optogenetic), virological, and behavioral strategies to explore opiate-HIV interactions in murine (in vitro and in vivo) and human (in vitro) models. The candidate will be provided with significant training in those disciplines with which they are less familiar, as well as significant mentoring to facilitate their transition to an independent research career.
Interested individuals are encouraged to forward a curriculum vitae, a list of three references, and a statement of research interests and career goals to Dr. Kurt F. Hauser, Professor, Department of Pharmacology & Toxicology, Institute for Drug & Alcohol Studies, VCU School of Medicine, Kontos Medical Science Building, 1217 E. Marshall St., Richmond, VA 23298 (email:kurt.hauser@vcuhealth.org) or Dr. Pamela E. Knapp, Professor, Department of Anatomy and Neurobiology, Institute for Drug and Alcohol Studies, VCU School of Medicine, Kontos Medical Science Building, 1217 East Marshall Street, Richmond, VA 23298 (e-mail: pamela.knapp@vcuhealth.org).
13.3.2017 | Ajankohtaista
PhD student position in the research group of Inari Kursula at the Department of Biomedicine, University of Bergen, Norway.
We are looking for a highly-motivated PhD candidate for a structural biology/biochemical project concerning malaria parasite actin-myosin motors.
Deadline for applications: 31.3.2017.
Post-doctoral position in the research group of Inari Kursula at the Department of Biomedicine, University of Bergen, Norway.
We are looking for a highly-motivated candidate with a strong background in biophysics/microscopy and interest in understanding molecular mechanism of cell motility. Deadline for applications: 31.3.2017.
9.3.2017 | Ajankohtaista
Postdoctoral Research Opportunities in Infection Biology and Molecular Infection Medicine at Umeå University, Sweden
The programme is open to all nationalities and features of the positions include:
• Development of a project proposal forms the basis for recruitment
• Funding for research within a multidisciplinary environment
• Two years of secure funding
• Access to UCMR-MIMS-affiliated core facilities and technical platforms.
The positions are full-time for 24 months.
Deadline: April 9th, 2017
7.3.2017 | Ajankohtaista
Two postdoctoral positions, funded by an NIH Ruth L. Kirschstein National Research Service Award, are available on or after February 1, 2017 in the Pittsburgh Center for Pain Research (PCPR) at the University of Pittsburgh. The PCPR aims to recruit and train the next generation of leaders in pain research, focusing on cutting-edge theories, techniques, and research strategies. Areas of research may include, but are not limited to, basic and/or clinical investigations on the molecular and cellular changes that contribute to the development of chronic pain, analysis of CNS pain circuits, human imaging studies, pain genetics, and fundamental processes underlying pain, itch, or touch. In addition, this training program provides a clinical component to the education of postdoctoral fellows with exposure to the assessment, diagnosis and treatment of chronic pain patients. Systematic and structured training will be provided in the laboratories of leading scientists with wide-ranging interests and research programs. www.paincenter.pitt.edu/people/faculty
Qualifications:
Applicants must have a PhD or MD/PhD degree in Neuroscience, Biology, Molecular Biology, Pharmacology, Physiology, Bioengineering, or a related field, and have demonstrated excellence in research. Previous experience in pain research is not required.
To be eligible for the NIH T32 program, the applicants must be either US citizens or permanent residents. The training program provides a competitive salary (based on NIH stipend levels), a travel and research allowance, health insurance, and tuition assistance.
Individuals from underrepresented racial and ethnic groups, people with disabilities, and individuals from disadvantaged economic, social, cultural, or educational backgrounds are encouraged to apply.
Candidates should submit a CV, a brief description of research interests and career goals, and contact information for three references to Joanne Hirt (hirtj@upmc.edu) or to Dr. Howard Gutstein (gutsteinhb@upmc.edu )
Applications will be accepted until the positions are filled.