Ajankohtaista

Post-Doctoral Fellow in Bioengineering, Hematopoietic Stem Cell Biology and Blood Disorders: Boston, MA, United States

20.2.2017 | Ajankohtaista

Join Our Team 

Post-Doctoral Fellow in Bioengineering, Hematopoietic Stem Cell Biology and Blood Disorders: Boston, MA, United States

Two postdoctoral fellow positions are available in the Dhvanit Shah Laboratory (www.shahlaboratory.org) at the Division of Hematology, Brigham and Women’s Hospital (BWH) & Harvard Medical School (HMS), Boston MA, United States.

The Shah laboratory is located in a dynamic Harvard Medical Area that offers excellent opportunities for intellectual exchange and collaborations among investigators from diverse fields. We investigate the origin, development, and differentiation of hematopoietic stem cells (HSCs), and their utility in treating patients with blood and bone-marrow diseases. We have expertise in utilizing zebrafish, mice, and human induced pluripotent stem (iPS) cells to analyze novel genes and mechanisms important for blood formation. Our goals are to utilize our knowledge in developing cellular- and mechanism-based therapies as well as generating functional HSCs for the treatment of hematological diseases.

 Position # 1: Hematopoietic Stem Cell Development and Disorders

Ideal candidate will have Ph.D., M.D., or M.D./Ph.D. in Regenerative Medicine, Stem Cells, Immunotherapy, Hematology, Oncology, and/or Biology. This position offers an excellent opportunity to learn and apply skills in directed differentiation of mouse embryonic stem cells and/or human induced pluripotent stem cells, epigenetics, HSC transplant, xenograft, computational biology, high-throughput screening, gene-editing, and/or molecular and cellular biology techniques. Strong background in one or more of these areas is preferred. Qualified candidate should be able to work independently as well as in a group environment.

Position # 2: Bioengineering of 3D Scaffold Development

Ideal candidate will have Ph.D., M.D., or M.D./Ph.D. in Tissue Engineering, Biomaterials, Biophysics, Machine Learning, Systems Biology, Chemical Engineering, and/or Drug Development. This position offers an excellent opportunity to learn and apply skills in organoid development, 3D bio-printing, Bio-MEMS, artificial intelligence, microfluidics, proteomics, and/or medicinal chemistry. Strong background in one or more of these areas is preferred. Qualified candidate should be able to work independently as well as in a group environment.

Interested candidates should send their cover letter, CV, and contact details of three references to:

Dr. Dhvanit I. Shah

Division of Hematology,

Brigham and Women’s Hospital &

Harvard Medical School

One Blackfan Circle, Karp 06.211

Boston, MA 02115

dshahlab@gmail.com  

 BWH & HMS are an affirmative action/equal opportunity employers.

MSc thesis project, FinVector Vision Therapies Oy

20.2.2017 | Ajankohtaista

FinVector Vision Therapies Oy (FVT) is searching for highly motivated graduate student(s) to conduct MSc thesis research project(s) on gene therapy, virology and cell biology related applications.

We are mainly looking for students from the fields of virology, biotechnology, molecular medicine, biomedicine, genetics, immunology or cell- and molecular biology, but all life science backgrounds can be considered. The projects can be tailored to different students and skillsets, but beneficial technical skills include cell culture, transfections, qPCR, ChIP(-seq), high-throughput sequencing, bioinformatics, chromatography and protein chemistry techniques. Ideal graduate student is forward thinking, organized team player with good oral and written communication in English. The project(s) will last 6 months, of which the last 3 months can be paid according to student performance. First project can be started at short notice.

FVT is a world leader in the research and development of Viral-Based Gene Therapy products. We are authorized under EMA for the production of gene therapy products for clinical and commercial supply. http://www.finvector.com/

For more information/to apply, please contact vesa.turkki@finvector.com

Postdoc position in the lab of Dr. Hongxia Zhao for the study of mitochondrial membrane protein functions, University of Helsinki

15.2.2017 | Ajankohtaista

An open call for a post-doctoral researcher position in the lab of Dr. Hongxia Zhao, www.biocenter.helsinki.fi/bi/zhao/  in Institute of Biotechnology, University of Helsinki, for the study of mitochondrial membrane protein functions.

We are looking for a highly motivated, enthusiastic and interactive candidate with experience in cell biology. Candidates with experience in mitochondrial biology are particularly encouraged to apply. Good communication skills in English are important.

To apply, please send your application (including a cover letter, CV and preferably two references) by email to hongxia.zhao@helsinki.fi. Further inquiries can be directed to the same address.

 

Doctoral student position in the Celiac Disease Research Center (CeliRes)

14.2.2017 | Ajankohtaista
We are looking for a doctoral student to join the Celiac Disease Research Center (CeliRes). CeliRes is committed to conducting high-quality multidisclipinary research ranging from epidemiological and clinical studies to genetics, immunobiology and microbiology.  The project of the doctoral student will involve the pathogenetic mechanism of celiac disease and its skin manifestation, dermatitis herpetiformis. A successful candidate has MSc degree/equivalent and is self-motivated. Previous experience in biomedical and immunobiological research techniques is considered as an advantage.
Salary: The salary will be based on the demand level chart for the teaching and research staff of Finnish Universities. The preliminary level of demand is 2-4. In addition to the basic salary, a supplementary salary component will be paid according to the personal performance.
There is a four month’s trial period in the beginning of the employment.
Application process:  Applications must be submitted by the online application form of the University of Tampere at https://uta.rekrytointi.com/paikat/?o=A_RJ&jgid=1&jid=889 by March 13th, 2017, at 15.45 local time. Please attach to your application a letter of motivation (indicating who you applied for this position), and a CV including two references with their contact information.
For additional information, please contact:
University Researcher Katri Lindfors katri.lindfors (at) uta.fi (position)

HR Specialist Jonna Rinne jonna.rinne (at) uta.fi (recruitment process).

12 Early Stage Researcher Positions (for PhD studies) for MSCA-ITN Project “CAPICE”

13.2.2017 | Ajankohtaista

CAPICE: general description

In this ambitious and inspiring network, 12 Early Stage Researches (ESRs; PhD-level training) will be trained in the broad field of psychiatric genomics, investigating the role of genetics and epigenetics, and their interplay with the environment, in the development and persistence of childhood and adolescent psychopathology. Through biological pathway analyses, drug target validation and the building of prediction models, these results will ultimately be translated to the clinic. Analyses will be performed in large international collaborations, making use of the wealth of data available across a range of European birth and adolescent cohorts.

ESRs will be supervised by leaders in the field located at institutions across Europe in Italy (University of Cagliari), The Netherlands (Vrije Universiteit Amsterdam, Erasmus University Medical Center Rotterdam, University of Twente), Sweden (Karolinska Institute, Gøthenburg University, Janssen Pharmaceutical) and the UK (Imperial College London, King’s College London, University of Bristol). At the end of this project the ESRs will be part of a broad international network consisting of academic and non-academic partners.

Candidates with a background in statistical genetics, bioinformatics, psychology, psychiatry or neuroscience are invited to apply.

More information at http://academicpositions.eu/ad/capice/2017/12-early-stage-researcher-positions-for-phd-studies-for-msca-itn-project-capice/97232

Application deadline: 1.3.2017

 

PostDoc Position at the University of Basel – Single-cell and personalized regulatory genomics

13.2.2017 | Ajankohtaista

https://www.researchgate.net/job/883483_PostDoc_Position-Single-cell_and_personalized_regulatory_genomics

 

JOB DESCRIPTION

Post-doc position in single-cell and personalized regulatory genomics

Biozentrum, of Basel, Switzerland

A post-doctoral position is available in the group of Prof. Erik van Nimwegen at the Biozentrum of the of Basel and Swiss Institute of Bioinformatics.

We are looking for highly motivated individuals with strong mathematical and computational skills that are interested in performing theoretical/computational research in regulatory genomics, especially in the areas of single-cell gene regulation and personalized regulatory networks.

Our research group is highly interdisciplinary, involving both an experimental section where researchers with a background in molecular biology are experimentally studying genome evolution and gene regulation at the single cell level in bacteria, and a theoretical section where researchers with backgrounds in theoretical physics, computer science, and applied mathematics are using techniques from Bayesian probability, evolutionary theory, dynamical systems theory, and stochastic processes, to study the function and evolution of genome-wide regulatory networks in cells. We are particularly interested in uncovering the principles by which genome-wide regulatory networks specify and maintain cell identity in multi-cellular organisms, how cells control and exploit the noise in gene regulatory processes, and how gene regulation evolves. A list of our group’s publications can be found here.

For this position we are looking for candidates interested in developing methods for analysis of the regulatory networks that control cell fate decisions and cell identity in multi-cellular eukaryotes.

Our lab has long worked on developing methods for genome-wide prediction of regulatory sites,e.g Siddhartan et al. 2005, Pachkov et al. 2007, Arnold et al. 2011, Khorshid et al. 2013, and in recent years we have developed several methods for analyzing gene regulatory networks by modeling genome-wide gene expression and chromatin state data in terms of constellations of regulatory sites, e.g. Fantom Consortium 2009, Arnold et al 2012, Balwierz et al. 2014. We are interested in extending these methods to model single-cell regulatory dynamics and cell fate decisions by analysis of single-cell RNA-seq data, and to incorporate the effects of SNPs and other genetic variants on the functioning of gene regulatory networks in mammals. As part of these efforts we are collaborating within the BrainStemX project on mammalian forebrain development. The precise topic of the research project will be determined jointly with the candidate and candidates that display initiative and independence will be given priority.

DESIRED SKILLS AND EXPERIENCE

  • Candidates should have strong mathematical and computational skills, and experience with analysis of next-generation sequencing data
  • Experience in areas such as stochastic processes, dynamical systems theory, and Bayesian statistics is a plus
  • Candidates do not necessarily have to have a biological background but should have a strong desire to directly work with experimental biologists
  • The candidates should have a good knowledge of English
  • German is helpful but not necessary
  • The salary is generous and is set according to the guidelines of the Swiss National Science Foundation
  • The start date will by mutual arrangement

To apply, please send a single pdf containing your application letter, CV, and the names of two references by clicking on the ”Apply for this job” button.

Review of applications will begin immediately.

ABOUT THE EMPLOYER

Basel is a very international city and a center of life science research, with over 900 life science research companies in the area, including Novartis and Roche. Several other academic institutions are also in the city, including the Friedrich Miescher Institute, the ETH Zurich Biosystems Science and Engineering Department, and the Swiss Tropical Institute. The city is less than 5km from both France and Germany and an hour and a half from the Swiss Alps.

Faculty of Medicine and Life Sciences at the University of Tampere invites applications for a Postdoctoral Researcher position

8.2.2017 | Ajankohtaista
Faculty of Medicine and Life Sciences at the University of Tampere invites applications for a Postdoctoral Researcher position. The fixed-term position will be filled for one year (twelve months) with a possibility for extension for at least two additional years, starting on March 1, 2017, or as soon as possible.
Deadline for application is 15.2.2017 at 15:45. Application and more information at https://uta.rekrytointi.com/paikat/?o=A_RJ&jgid=3&jid=883

Exciting PhD positions at the European Molecular Biology Laboratory (EMBL)

8.2.2017 | Ajankohtaista
Job Description
The European Molecular Biology Laboratory (EMBL) invites you to apply for PhD positions in Heidelberg, Grenoble Hamburg, Hinxton (near Cambridge), and Monterotondo (near Rome).
 Would you like to contribute your creativity to an international team of scientists from all disciplines focusing on basic research in the area of molecular life sciences?
 We invite candidates with background in Biology, Chemistry, Physics, Mathematics, Computer Science, Engineering and Molecular Medicine to apply.
 
EMBL opens the door to your scientific career: our students have an outstanding publication record, are a vital part of our global collaborations and receive their degrees jointly with our network of excellent partner universities in 17 different countries.
 Our PhD positions come with generous fellowships, including broad health care benefits and pension access.

Application Instructions
Please apply online through www.embl.de/training/eipp/application/index.html   
The registration deadline is 19.10.2015
The deadline for submission of the online application is 26.10.2015
Interviews will take place in February 2016
 
Additional Information
EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation.
 Successful candidates would start their work at EMBL latest by mid of October 2016.
 For further information, see our web page or contact EMBL Graduate Office.