27.5.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3616439875
About the job
Laboratory coordinator position in stem cell biology
The Lengefeld laboratory is working on understanding how the failure to regenerate tissue with age is a major health issue. A contributor to this decline is the loss of stem cell function. Despite the essential role of stem cells, it is still unclear how they fail to maintain their functions during aging and disease. We discovered a new aspect of stem cell aging in vivo: cellular enlargement. With age and damage, stem cells increase in size causing their functional decline. However, we are only beginning to understand how size impacts stem cell fitness and the physiological importance of this process remains unsolved.
Laboratory website: http://lengefeldlab.com/
The laboratory of Assistant Professor Dr. Jette Lengefeld is inviting applications for a lab coordinator position. This laboratory coordinator position harbors several functions. The main responsibility is to organize the day-to-day actions of the laboratory and research. The main activities are listed below:
- Conducting own research and supporting research projects of lab members. Tasks will include mouse genotyping, cell culture, stem cell isolation using flow cytometry, data management and microscopy.
- Coordination of lab structure involving maintaining of mouse colony and lab materials
- Performing administrative task for grant applications and management, organization of research meetings and bills
Qualifications and experience:
We expect the suitable candidate to hold an B. SC., M.Sc. or Ph.D. degree in the field related to biology; knowledge in experimental mouse work and cellular biology are beneficial. The candidate should be fluent in English. Finnish skills are considered as an advantage but are not required.
Salary and contract:
The position is offered for a fixed term of five years 2023 -2028 or as negotiated. Salary will depend upon the applicant’s level of skills, knowledge, and abilities and is based on the university salary system. A trial period of 6 months will be applied.
Why work with us?
Helsinki Institute of Life Science, HiLIFE, offers an international, inspiring, and supportive work environment. HiLIFE is a new life science institute at the University of Helsinki established in 2017 supporting high quality research across campuses and life science faculties. HiLIFE builds on existing strengths, new recruits and partnerships to create an attractive international environment for solving grand challenges in health, food, and environment. It coordinates research infrastructures in life sciences, provides research-based interdisciplinary training and supports researchers within its units and partner faculties. In 2019 HiLIFE has a staff of 600 and a budget of 59 M€.
For more information on the Institute, please visit https://www.helsinki.fi/en/helsinki-institute-of-life-science
The University of Helsinki provides its employees a wide range of opportunities and benefits, such as support for competence development and application for research projects, library, sports and welfare services. Read more about career opportunities and benefits at https://www.helsinki.fi/en/about-us/careers.
The University of Helsinki, founded in 1640, is one of the world’s leading universities for multidisciplinary research. The university has an international academic community of 40,000 students and staff members. The University of Helsinki offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and professional development opportunities. The International Staff Services office assists employees from abroad with their transition to work and life in Finland.
Finland is a member of the EU, has high quality free schooling (also in English), generous family benefits and healthcare, and was recently ranked as the best country in the world for expat families and in the world’s top ten most livable cities. Finland and the Helsinki region possess top expertise in sciences in terms of a vibrant talent pool, leading research, strong support services and functioning collaboration networks. For more information about working at the University of Helsinki and living in Finland, please see https://www.helsinki.fi/en/about-us/careers
Interested?
Please submit your application, together with the required attachments, through the University of Helsinki electronic recruitment system by clicking the “Apply for the position” – link below. Internal applicants (i.e., current employees of the University of Helsinki) must submit their applications by logging in to the SAP system: https://msap.helsinki.fi. For technical support regarding the recruitment system, please contact ‘rekrytointi@helsinki.fi’.
Application should include the following documents as a single pdf file: cover letter (max 1 page), CV of max. 4 pages, full publication list, and names of three references.
The deadline for the applications is 15.07.2023, but the positions will be filled immediately once suitable candidates have been identified.
The University of Helsinki welcomes applications from people of any gender, linguistic and cultural background, or minority group.
If you have any questions about the position, please do not hesitate to contact Jette Lengefeld, Assistant Professor, jette.lengefeld(at)helsinki.fi. Further information on the recruitment process may be obtained from HR Specialist Anu Roine, anu.roine(at)helsinki.fi.
27.5.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3604038080
About the job
Description Of Position
We are looking for a highly motivated CMC Formulation / Analytical Scientist to lead biologics projects from research phase into early clinical development, with a specific focus on different types of antibodies as well as cell therapy.
Your main responsibility is to manage external drug substance and drug product development and external manufacturing sites. You have experience with early-stage development for therapeutic biologics. You will provide clear communication regarding CMC development pathway between internal experts, project management, external consultants and CDMO’s. You collaborate across a range of different experience levels and will foster productive collaborations within Orion R&D and Orion R&D cross-functional partners such as External Supplies Operations and Quality Assurance.
In this position you will:
- Ensure drug substance and drug product development plans are aligned with the project timelines.
- Actively contribute to cross-functional Biologics CMC strategic discussions.
- Actively communicate and manage timely initiation of CMC activities at CDMO in collaboration with research teams, external CMC consultants and internal and external Orion partners
- Ensure timely completion of all functional deliverables including reports and applicable quality and regulatory documents.
- Encourage ideas and drive for continuous improvement and champion initiatives within Pharmaceutical Sciences, Orion R&D organization and across R&D partner functions.
- Understand and comply with Orion Pharma’s safety, quality and regulatory policies and government regulations.
This permanent position is based in Turku or Espoo, Finland.
Description Of Unit
This position is situated in Biologics CMC unit, which belongs to Pharmaceutical Sciences department within Orion Pharma Research and Development. We operate in project CMC teams to develop new drug products for humans and animals in the exploratory phase of drug development process.
We offer
We offer a great team to join with skilled and highly motivated colleagues. Appreciation of colleagues and continuous development are part of our core values. We enable opportunities to utilize your skills and competencies widely as we continuously create something new.
Requirements
To succeed in this role, you possess the following:
- Ph.D. with 4+ years of industrial experience or MS Degree with at least 8+ years of related industrial experience preferred. Degree in Biologics Engineering, Biochemistry, Pharmaceutical Sciences or closely related field.
- Demonstrated technical experience in leading formulation and drug product process development of biologics, including process scale-up from laboratory to pilot scale.
- Lead cross-functional CMC developments and experience in managing global activities is highly desirable.
- Demonstrated capability to solve critical scientific and business problems.
- Excellent communication skills in English are required.
- Readiness to acquire and implement cGMP, cGLP and regulatory requirements for clinical development in EU and US.
In addition, you preferably have expertise in one or more of these areas:
- Biologics drug substance and drug product process development
- Biologics GMP manufacturing and IND/IMPD documentation
- Biologics analytical method development
Additional Information
If you are interested in this opportunity, please apply by 31 May 2023. We may process applications already during the application period, so please submit your application as soon as possible.
If you have any questions, please contact Director of Pharmaceutical Sciences, Bert van Veen Tel. +358 50 966 4625 on Tuesday 23 May 10-11 a.m. EET (UTC+02) or Thursday 25 May 10-11 a.m. EET (UTC+02).
Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person. Orion Corporation operates in more than 30 countries, where we Orionees, 3500 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.
27.5.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3614789456
About the job
Laboratory of Prof. Jussi Taipale at the Medical Systems Biology group at the Applied Tumour Genetic Program at University of Helsinki, Faculty of Medicine invites applications for the position of
POSTDOCTORAL RESEARCHERS (two positions)
Our research group is part of the Academy of Finland’s Centre of Excellence in Tumour Genetics Research. The laboratory focuses on the study of transcriptional control of cell growth, using functional genomics and systems biology. Current lines of work include high-throughput determination of binding sites and binding specificities of human transcription factors, using this information to identify regulatory elements that control cell growth during normal development or in cancer.
Qualifications
Applicants with a doctoral degree and strong background in molecular biology/bioinformatics who are interested in working in an inter-disciplinary environment are particularly encouraged to apply. Applicant must be able to work independently and have good communication skills in English. The chosen applicant is expected to reside in Finland while employed by the University of Helsinki.
What We Offer
The appointment will be initially for two years starting from September 2023. Trial period of six months will be applied. The monthly gross salary will be appr. 3200-3600 € per month depending on the appointee’s qualifications and experience. In addition, University of Helsinki offers comprehensive services to its employees, including occupational health care and opportunities for professional development. Applicants of any gender, linguistic and cultural background or from members of minority groups are welcomed. You can read more about working at the university on our website .
How To Apply
Please submit your application as a single PDF file containing your CV, publication list including impact factors and two letters of reference through the University’s electronic recruitment system by clicking “Apply for the position” link below. Applicants who are currently employed by the University of Helsinki are requested to submit their application via the SAP Fiori portal at https://msap.sap.helsinki.fi . The deadline for applications is 21 August 2023.
For further information on the position, please contact Petros Papadopoulos (petros.papadopoulos (at)helsinki.fi).
For information on the recruitment process, please contact HR Specialist Marja Meresto (hr-ltdk (at)helsinki.fi).
Selected publications from Taipale lab:
Sahu et al. Sequence determinants of human gene regulatory elements. Nature Genetics, 2022, April 283–294.
Sahu et al. Human cell transformation by combined lineage conversion and oncogene expression. Oncogene. 2021, Sept, 5533-5547.
Zhu et al. The interaction landscape between transcription factors and the nucleosome. Nature. 2018, Oct, 76-81.
Yin et al. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science, 2017, May 5;356(6337).
Yan et al. Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. Cell, 2013, 154, 801-13.
The Faculty of Medicine promotes high quality scientific research. It provides research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, and an international Master’s Programme in Translational Medicine. It also offers psychotherapist education. In addition to its teaching and research activities, the faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. The faculty aims to be one of the best medical research faculties in the world, while reinforcing its status as a distinguished institution of multidisciplinary education in healthcare.
The Faculty of Medicine at the University of Helsinki constitutes the academic medical centre together with HUS Helsinki University Hospital and the Helsinki Institute of Life Science (HiLIFE). This medical centre has been successful in international comparisons, ranking among the top 10 medical campuses in Europe and the top 50 globally.
Research Programs Unit (RPU) of the Faculty of Medicine consolidates demonstrated research excellence, with focused research programs addressing the greatest challenges in human health.
27.5.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3592860489
About the job
Scientist I, II – Molecular Diagnostics, Assay DevelopmentLocation: On-site Espoo, Finland
Travel: Occasional international (up to once per month)
Contract: Permanent
Language requirement: English
Hologic, Inc. is a leading developer, manufacturer and supplier of premium molecular diagnostic products and services that are used to diagnose human diseases, screen donated human blood and to aid in biomedical research. Hologic is also a leader in the development, manufacturing and sales of medical imaging systems and biopsy devices as well as surgical and treatment products, with an emphasis on serving the healthcare needs of women. Our business is dedicated to impacting the lives of people across the globe through the early detection of disease, improved diagnosis and less invasive treatments.
There has never been a more exciting time to join us. Bright people, working together to pioneer advances in human health care, have created Hologic’s success. Our company believes that people are our greatest asset and only by recruiting, hiring, developing and retaining the most talented employees can we continue to be successful. Our work atmosphere is stimulating, innovative and customer focused. We provide employees with state-of-the art tools and technology, a collaborative and passionate work environment and the ability to make a dramatic difference in the world of healthcare.
We are looking for two Scientists to join our Assay Research & Development team in Espoo, Finland. In Espoo R&D, we are developing new innovative molecular diagnostics products in infectious disease area on our Novodiag platform. These tests are targeted for the global health care markets and will be developed according to the European, US and other relevant regulatory standards and Hologic Science of Sure development process. You will join around 50 colleagues in Espoo R&D and work in very close collaboration with our R&D centers in Paris and San Diego, with expertise in e.g. assay development, chemistry, microbiology, bioinformatics, mechanical and electrical engineering, microfluidics, software and algorithm development. Espoo R&D is located in Keilaniemi, where we are working on multiple new product development projects.
We expect from candidates for all positions:
- Good verbal and written communication skills in English
- Excellent teamwork skills coupled with proactive way of working
- Analytical mindset and problem-solving skills
- Good computer skills, willingness to learn new software tools used in R&D
- Advanced knowledge and expertise in laboratory procedures and molecular biology methods, especially PCR, related instruments and equipment
- Basic knowledge of microbiology
The following skills are considered as plus:
- Experience in working in IVD, life-science or medical device companies as well as familiarity of the applicable regulations and standards in IVD test development (EU, USA, ROW)
- Experience in working in a global company
- Experience with relevant bioinformatics tools and algorithms
- Understanding/execution of basic statistical calculations and statistical design of experiments (DOE)
SCIENTIST 1
Essential Duties & Responsibilities:
- Designs and executes moderately complex experiments to complete a segment of the overall project and incorporates findings into design of future experiments.
- Integrates own data with those of others within and outside of the project team.
- Writes and reviews product documentation.
- Presents data to internal groups.
- Writes study protocols and reports covering several lines of experimentation.
- Operate complex lab equipment and perform routine maintenance/repair.
- Assists in the establishment of procedures and research methodologies.
- Provide recommendations and observations to scientific staff.
- Initiates literature review and searches.
- Trains others on project assay and serves as a resource for solving product issues.
- May oversee junior level Research Associates.
Education & Experience:
- Technical Bachelor Degree (AMK) with 3-5 years of experience
- MSc Molecular Biology, Biochemistry or related field with 1-2 years of experience
- Or related education and working experience in appropriate field
SCIENTIST 2
Essential Duties And Responsibilities
- Responsible for molecular diagnostic product development within a dynamic team environment. May also manage and mentor Research Associates/Scientists as part of daily responsibilities.
- Experience in one or more of the following areas:
- Research – Nucleic acid amplification methods and manipulation including purification, amplification, hybridization, etc. Genomic analysis including qPCR, DNA sequencing or NGS. D ata analysis using appropriate software (R, Excel, JMP etc.)
- Feasibility – Multiplex assay design (qPCR or similar technology), sample processing, assay formulation optimization and troubleshooting of automated workflows.
- Product Development – Formulation optimization including DOE; transfer of methods and formulations to manufacturing; establish QC methods and specifications for product release testing. Interface with SW and HW engineers to support software development, results processing, and instrument integration.
- Present work both internally and externally at scientific meetings.
- May serve as the R&D technical representative on a project Core Team.
- Collaborate and communicate effectively with junior level employees, peers, and cross-functional teams across all levels of the organization.
- MSc Molecular Biology, Biochemistry or related field with 3-5 years of experience, preferably industrial
- PhD Molecular Biology, Biochemistry or related field
- Or related education and working experience in appropriate field
So why join Hologic?
We are committed to making Hologic the company where top talent comes to grow. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career.
We offer a competitive salary and annual bonus scheme, one of our talent partners can discuss this in more detail with you.
From a benefits perspective, you will join our wide-ranging benefits policy including retirement savings plan, medical insurance and many more!
If you have the right skills and experience and want to join our team, apply today. We can’t wait to hear from you!
27.5.2023 | Avoimet työpaikat
https://rekry.saima.fi/certiahome/open_job_view.html?id=000014916&did=5600&lang=en&jc=14
We have a position open to lead the development and application of dynamic phenotypic screens applied to neurons differentiated from human iPS cells representing three rare diseases of the Ras pathway that affect the nervous system. The screens will be used to identify repurposable molecules with potential for rapid entry into clinical use.
The project makes use of optical probes and actuators together with high-throughput imaging and lab automation instrumentation at a facility developed by our lab. Please find more information about the EURAS consortium here and our involvement in it here.
Key Tasks and Responsibilities
- Generation of neural cultures expressing optical reporters and actuators from induced pluripotent stem cell lines in high density arrayed cultures.
- Using automation infrastructure to identify robust dynamic and longitudinal phenotypes of neurons in these cultures and deriving a screening assay
- Using automation infrastructure to perform screens of a drug library on differentiated neurons from a limited number of representative lines to identify hits
- Confirming and validating hits on a neural cultures originating from a larger range of iPS cell lines
- Supervision of junior researchers and collaboration with colleagues and project partners
- Documentation and reporting
Essential qualifications
- We are primarily looking for a person who has a relevant PhD degree in cell biology, molecular neuroscience or a related field. An applicant with a Masters’ degree and fewer qualifications may alternatively be considered for a Doctoral Researcher’s position or a Project Researcher’s position. In the case of a Doctoral Researcher, the applicant is expected to apply to join a doctoral programme of the University of Turku and have the corresponding required English language qualification or exemption.
- Experience in neuronal cell biology, cell signalling methods, gene transfer methods, fluorescence microscopy and neuronal cell culture
- Experience of data analysis pipelines with ImageJ/FIJI or equivalent
- Knowledge of screening concepts and statistic methods relevant to phenotypic screens
- Good knowledge of neuronal cell biology and cell signalling
- Strong motivation, persistence, initiative and independence
- Good knowledge of written and spoken English
Desirable qualifications
- Strong publication record in international journals in the field relevant to the position
- Experience with handing, transcription-factor based differentiation and maintenance of iPS cells to neuronal lineages
- Experience with the application of lab automation infrastructure
- Generation, titer quantification and use of viral gene transfer systems (AAV & lenti)
- Experience with use of imaging-based signalling reporters and dynamic and longitudinal imaging
- Good knowledge of R, Python and/or Java
- Familiarity with 3D printing and open source hardware development
- Experience of molecular cloning and optical reporter/actuator design
Our selection criteria are based on the principle of finding the most qualified and suitable candidate for the work. In practice, this means that not only education, publications and working experience but also personal qualities, communication and motivation factors and other relevant criteria will be considered.
Duration of contract
The start of employments is negotiable, preferably in August–September 2023. The position is fixed-term for 24 months (negotiable), with an eventual possibility for an extension. A six (6) month trial period applies to the position. The qualification requirements of the positions are written in the University of Turku Rules of Procedure.
What we offer you
The salary is determined in accordance with the university salary system for teaching and research personnel and will depend on the degree and qualifications of the applicant. The salary for a Doctoral Researcher/Project Researcher will be in average 2300 – 2500 euro/month and for a Post-Doctoral Researcher in average 3300 – 3500 euro/month depending on competence and experience.
Salaried positions in Finland automatically include payments to a pension fund, unemployment funds, an extensive occupational healthcare, affordable sports services and even a holiday allowance. All these positions belong to the personnel group of teaching and research personnel and have flexible working possibilities as we support a work-life balance.
What to do next
Please submit your application through the online application system no later than 19.6.2023. Kindly use a link to the online application system https://www.utu.fi/en/university/come-work-with-us.
In addition, applications must have the following enclosures (in English):
1) motivation letter (max 1 page) focusing on your strengths related to our research topics
2) CV (max 2 pages)
3) copies of degree certificates
4) contact details for at least three referees (name, working place, e-mail address)
5) a list of publications, highlighting the five most relevant ones
In case you need help with the application process, please turn to biocityhrservices(at)utu.fi
About us
Read more about the team and their research
Turku Bioscience is an advanced research centre hosting, in a single site, research teams with expertise in high-end core facilities housed in this independent unit affiliated with both the University of Turku and Åbo Akademi University. The facilities for proteomics, screening and cell imaging the most relevant to the projects and are situated either in close proximity to or within our lab space, facilitating internationally competitive science in a stimulating, highly networked international community with more than half of the personnel having an international background. The working language is English. Supercomputer facilities at the Center for Scientific Computing (csc.fi) will also be used. More details about the departmental infrastructure can be found at bioscience.fi
We value equality and diversity in our work community and encourage qualified applicants, regardless of background, to apply for our open positions. Read more about us as an employer on the “Come Work with Us!” page and the welcome services for newcomers
For further information about the position, please don’t hesitate to contact michael.courtney(at)utu.fi
27.5.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3617921611
INVITATION FOR APPLICATIONS
Postdoctoral researcher
We are looking for a skilled postdoctoral fellow with a bioinformatic, computational, and/or statistical, background in genetics and/or functional genomics at the Institute for Molecular Medicine Finland FIMM , Helsinki Institute of Life Science, HiLIFE in the research groups of Professor Aarno Palotie (Research Group Palotie ) and Dr. Olli Pietiläinen ( Research Group Pietiläinen ). The position is part of research program that aims to discover biological mechanisms in schizophrenia and related neuropsychiatric disorders. The program bridges multidisciplinary group of researchers in the interface of genetic discoveries and multi-omic molecular biology using collections from over 500 000 genotyped participants from clinical and population studies with medical data. These include the FinnGen ( https://www.finngen.fi/en ) and SUPER studies ( https://www.superfinland.fi/english ). The Palotie group applies modern large-scale genetic analysis approaches to discover genetic mechanisms in common diseases with focus on neurological, neurodevelopmental, and neuropsychiatric traits. Palotie leads major research efforts at the University of Helsinki and The Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard. The Pietiläinen group combines state-of-art functional genomics and molecular cell biology approaches to understand how genetic risk factors identified in the disorders mediate their causative effects in human cells. The Pietiläinen laboratory is based at the Neuroscience Center and has close links with the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard ( https://www.broadinstitute.org/stanley ).
Role description:
We are seeking a postdoctoral researcher to work on a multidisciplinary project that utilizes genomic and medical registry data from over 500 000 individuals and a collection human induce pluripotent stem cells (iPSC) from genetically defined patients and controls. With these resources our goal is to model genetic and cellular processes involved in neuropsychiatric disorders. We are looking for a person for planning, conducting, and supervising multifaceted analysis of genetic and multi-omic data generated from the study participants and human cellular models, including RNA sequencing, and proteomics.
Key Requirements
We are looking for a highly motivated and creative person with a primary interest in molecular genetics and genomics data analysis to discover mechanisms in neurological disorders, and to work in multidisciplinary team of clinical, wet lab, and computational scientists. Candidates should have a PhD in bioinformatics, statistical genetics, applied statistics or mathematics with experience in genetic and/or functional genomics data analysis. We require previous experience and skills in research computing in high-performance cluster computing environment and/or cloud computing. The ideal candidate will have experience in at least one of the aforementioned areas, and a interest in the others.
The position is available from August 2023 onwards, or earlier, if required. It is a two-year fixed-term position, with a possibility of extension. Trial period of 6 months will be applied.
The salary will be based on level 5 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance with the overall starting salary amounting to approximately 3600 – 4500 EUR per month, depending on the qualifications and previous relevant research experience of the candidate.
Please submit your application via the University of Helsinki Recruitment System by clicking the ‘Apply now’ button below. If you need support with the recruitment system, please contact recruitment@helsinki.fi.
Please attach the following documents to your application as a single PDF file:
- CV (including publications)
- cover letter (maximum 1 page) that details your past experience and motivation
- contact details of at least two references
The deadline for applications is June 30th, 2023. Interviews will be conducted either in person or online. For more information on the position, please contact Dr. Olli Pietiläinen (olli.pietilainen@helsinki.fi).
University of Helsinki
The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.
Helsinki Institute of Life Science
Helsinki Institute of Life Science (HiLIFE) is a new institute established in 2017 that supports high quality life science research across the University campuses and faculties. HiLIFE builds on existing strengths and new recruits and partnerships to create an attractive international environment for researchers to solve grand challenges in health, food, and environment. HiLIFE coordinates research infrastructures in life sciences and provides research-based interdisciplinary training.
Institute for Molecular Medicine Finland
The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki – a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community
HiLIFE -Neuroscience Center
The Neuroscience Center is an international research unit within Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki, a leading Nordic university with a strong commitment to life science research. The research focus of NC is on translational brain plasticity. We carry out research relevant for the human brain both in health and disease, and during development and aging, by applying versatile approaches and modern technology platforms. NC aims at making fundamental discoveries about brain functions and especially translate research findings into improvements in the treatment, prevention and diagnosis of psychiatric and neurological disorders. The research in NC spans across several scales from stem cell research and molecular neuroscience to systems and cognitive neuroscience in both animal and human models.The research groups of NC conduct research in neuroscience at the highest international level and actively apply the results for the benefit of the society. NC collaborates actively with other units of HiLIFE and faculties of the University of Helsinki, Helsinki University Central Hospital, and Neurocenter Finland.
18.4.2023 | Avoimet työpaikat
https://www.admescope.com/about-us/careers/senior-in-vivo-scientist.html
18 April 2023
Admescope (www.admescope.com) provides research services to pharmaceutical companies and thus we contribute to discovery and development of new therapies to promote people´s health. The special expertise of our rapidly growing company is in drug metabolism, drug-drug interactions, quantitative bioanalysis and pharmacokinetic studies (ADME), and toxicology. The company offers versatile and challenging tasks as a partner of international pharmaceutical and biotech companies. Admescope (Symeres Finland Oy) is part of the Dutch company Symeres, which employs approximately 600 people in the Netherlands, Finland, the Czech Republic, and the USA (www.symeres.com).
We are hiring a
Senior In vivo Scientist
to join our DMPK team to support our customers’ drug discovery and development projects.
The position comprises mainly of design and supervision of in vivo DMPK studies, collaboration with supporting in-house teams, operational guidance of the laboratory team, data processing and analysis, and study report generation.
You have a university degree in a suitable field (e.g. pharmacy, biology or toxicology) and preferably hold a PhD degree. You have a strong background in in vivo sciences, and ideally are experienced in setting up novel procedures in a laboratory environment. Any experience in DMPK sciences, or surgical techniques is considered a benefit. Also, understanding of pharmacokinetic concepts as well as relevant software will be valuable. You are effective in managing tasks with deadlines, recognize when prioritization is a path forward, and work well as a team member. The position requires good communication skills in English, fluency with Windows programs and completion of appropriate laboratory animal course (FELASA C-category).
The position will be filled in spring 2023, as soon as a suitable person is identified.
We offer an interesting, versatile, and challenging position in a strongly growing company with a great atmosphere, and colleagues across our global organization. Furthermore, you will have an opportunity to be part of a continuously evolving drug discovery and development landscape. The position is available at our site in Oulu, Finland, and is a full-time position.
Please send your application with salary request along with your CV, highlighting the relevant education and work experience to recruitment@admescope.com, with email subject line “Senior In vivo Scientist”. Please apply at the latest on May 14th, 2023.
Vacancy is open for EU residents only.
Email: recruitment@admescope.com
16.4.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3565952808
About the job
Haemme terveystieteiden tiedekunnan tohtoriohjelmiin yhteensä 23 väitöskirjatutkijaa. Tehtävät sijoittuvat terveystieteiden tiedekuntaan Kuopion kampukselle ja alkavat 1.1.2024 (tai sopimuksen mukaan ko. vuoden aikana). Lue lisää alta, ja hae viimeistään 9.5.2023.
Tehtävä ja palkkaus
Tämän hakuilmoituksen kautta voi hakea väitöskirjatutkijan tehtävää terveystieteiden tohtoriohjelmassa, joka kouluttaa korkeatasoisia ja kansainvälisesti orientoituneita tutkijoita ja asiantuntijoita erilaisiin vaativiin kansallisiin ja kansainvälisiin tehtäviin. Tohtoriohjelma on monitieteinen ja se kattaa monipuolisesti seuraavat terveystieteiden alat: epidemiologia, geriatria, hoitotiede, kansanterveystiede (ml. ergonomia), liikunta- ja urheilulääketiede, ravitsemustiede (ml. elintarviketieteet), työterveys ja yleislääketiede.
Väitöskirjatutkijan tehtävänä on väitöskirjatyön tekeminen hyväksytyn tutkimussuunnitelman mukaisesti. Tavoitteena on tohtorin tutkinnon suorittaminen neljässä vuodessa päätoimisesti opiskellen rahoituslähteestä riippumatta.
Väitöskirjatutkijan tehtävät täytetään 1.1.2024 alkaen tai sopimuksen mukaan ko. vuoden aikana. Väitöskirjatutkijan tehtävän ja sen ajanjakson myöntämisessä huomioidaan aikaisemmat nuoremman tutkijan/väitöskirjatutkijan palvelussuhdejaksot rahoituslähteestä riippumatta. Tohtorikoulutuspaikan voi saada yhteensä maksimissaan neljän vuoden ajaksi. Uuden työntekijän tullessa tehtävään käytetään koeaikaa. Määräaikaisuuden perusteena on jatko-opintoihin liittyvä väitöskirjatyö.
Väitöskirjatutkijan tehtävää voi hakea kokoaikaisena tai osa-aikaisena. Osa-aikainen väitöskirjatutkijan paikka tulee rahoittaa yhteisrahoitteisena toisen rahoituslähteen (esim. yliopiston ulkopuolinen apuraha tai toinen organisaatio) kanssa, siten että rahoituskokonaisuus mahdollistaa kokoaikaisen väitöskirjatyön tekemisen. Haussa voi hakea myös yksittäisiä tutkijakuukausia.
Tehtävän palkkaus määräytyy yliopistojen opetus- ja tutkimushenkilöstön palkkausjärjestelmän mukaisesti. Palkka koostuu tehtäväkohtaisesta palkanosasta ja henkilökohtaiseen suoriutumiseen perustuvasta palkanosasta. Tässä tehtävässä tehtäväkohtainen palkanosa on vaativuustasoluokittelussa tasoilla 2–4 väitöskirjatutkimuksen ja jatko-opintojen vaiheesta riippuen. Lisäksi maksetaan henkilökohtaiseen suoriutumiseen perustuvaa palkanosaa, joka on 6–50 % tehtäväkohtaisesta palkanosasta. Palkka työsuhteen alkaessa on noin 2 413–3 164 €/kk.
Mitä edellytämme sinulta
- olet jatkokoulutuskelpoinen; sinulla on soveltuva ylempi korkeakoulu- tai ylempi ammattikorkeakoulututkinto tai soveltuva ulkomainen koulutus, joka asianomaisessa maassa antaa kelpoisuuden vastaaviin korkeakouluopintoihin,
- sinulla on hyvä englannin kielen taito,
- täytät tohtoriohjelmasi opiskelijavalinnan kriteerit,
- olet suunnittelemassa tai tekemässä ensimmäistä tohtorintutkintoasi,
- olet Itä-Suomen yliopiston jo kirjoilla oleva jatko-opiskelija tai suunnittelet tekeväsi tohtorintutkintosi Itä-Suomen yliopistossa. Myös maisterintutkinnon loppuvaiheen opiskelijat voivat hakea paikkoja edellyttäen, että tutkinto on valmis 31.7.2023 mennessä ja tutkintotodistuksen kopio toimitettu tiedekuntaan 31.8.2023 mennessä,
- olet tehnyt väitöskirjatutkimustasi 31.12.2023 mennessä (täysipäiväisesti) alle neljä vuotta.
Tarjoamme sinulle
- mielenkiintoisen työtehtävän osana kansainvälistä, luovaa, osallistuvaa ja osallistavaa yliopistoyhteisöä,
- mahdollisuuden joustavaan monipaikkatyöhön,
- Itä-Suomen yliopiston henkilöstöedut, joihin kuuluvat muun muassa kattava työterveyshuolto, laaja henkilöstökoulutustarjonta, edulliset kampusravintolalounaat, Sykettä-liikuntapalvelut ja mahdollisuus työsuhdepolkupyörään.
Hae näin
Jätä hakemus viimeistään 9.5.2023 sähköisellä hakulomakkeella. Väitöskirjatutkijan paikkaa tulee hakea siitä tohtoriohjelmasta, josta olet hakenut/tulet hakemaan jatko-opinto-oikeutta Itä-Suomen yliopistoon.
Huomioi, että hakemukseen tulee liittää mukaan seuraavat liitteet englanninkielisenä:
- ansioluettelo (http://www.tenk.fi/fi/tutkijan-ansioluettelomalli)
- julkaisuluettelo, jossa on eritelty väitöskirjaan sisällytettävät julkaisut (https://www.aka.fi/julkaisuluettelo/) tai julkaisuluettelo voidaan sisällyttää ansioluetteloon
- Tutkimussuunnitelma ml. tutkimuksen rahoitussuunnitelma, jossa kuvataan tutkimuksen edellyttämät ja olemassa olevat resurssit sekä lyhyt kuvaus tutkimuksen merkityksestä/vaikuttavuudesta. Jo kirjoilla olevien jatko-opiskelijoiden tulee toimittaa päivitetty tutkimussuunnitelma sisältäen selvityksen väitöskirjatyön edistymisestä ja aikataulusuunnitelman väitöskirjatyön loppuunsaattamisesta ja esitarkastuksen käynnistämisestä. Maksimipituus on 3 sivua ilman kirjallisuusviitteitä. Ks. Terveystieteiden tiedekunnan Tutkimussuunnitelman ohje: https://www.uef.fi/fi/avoimet-tyopaikat#paragraph-10004
- Motivaatiokirje (1 sivu), jossa hakija kuvaa motivaatioitaan jatko-opintoihin ja tutkimuksen tekemiseen
- Tutkintotodistuksen kopio ja opintorekisteriote jatko-opintoihin oikeuttavasta korkeakoulututkinnosta henkilöiltä, joilla ei ole jatko-opinto-oikeutta Itä-Suomen yliopistossa
Vain kaikki hakuilmoituksen mukaiset liitteet sisältävät hakemukset arvioidaan ja huomioidaan valinnassa. Hakemukset arvioidaan yhtenäisin kriteerein hyödyntäen ulkopuolisia asiantuntijoita.
Tutkimussuunnitelma arvioidaan seuraavilla kriteereillä: tutkimussuunnitelman laatu ja selkeys, tutkimussuunnitelman uutuusarvo ja toteuttamiskelpoisuus väitöskirjatutkimuksena, hakijan näytöt aikaisemmasta tutkimustyöstä ja hakijan motivoituneisuus motivaatiokirjeen perusteella.
Arviointiin voi sisältyä haastattelu. Tavoitteena on, että tiedekunta tekee päätöksen paikoille valittavista henkilöistä syyskuun loppuun mennessä.
Kysymyksiä?
ttjatkokoulutus@uef.fi
Terveystieteiden tiedekunta toimii Itä-Suomen yliopiston Kuopion kampuksella. Tiedekunnassa koulutetaan lääkäreitä, hammaslääkäreitä, ravitsemusterapeutteja, farmaseutteja ja proviisoreja sekä muita keskeisiä asiantuntijoita terveydenhuollon eri aloille. Tiedekunta on hyvin tutkimusintensiivinen. Kansainvälisesti korkeatasoinen ja monitieteinen tutkimus kytkeytyy vahvasti yliopiston strategiassa tunnistettuihin tutkimusalueisiin. Tiedekunnassa on noin 3090 perustutkinto-opiskelijaa ja noin 580 jatko-opiskelijaa. Henkilökuntaa tiedekunnassa on 800.
Itä-Suomen yliopisto (UEF) on yksi Suomen monialaisimmista tiedeyliopistoista. Yliopistossamme työskentelee noin 3200 tutkijaa, opettajaa ja asiantuntijaa, ja yhteisöömme kuuluu noin 16000 tutkinto-opiskelijaa. Kampuksemme toimivat Joensuussa ja Kuopiossa. Tutkimuksemme on useilla aloilla maailman kärkeä, ja tuotamme tutkittua tietoa avoimesti käytettäväksi ja kaikkien hyväksi. Tutustu yliopistoomme verkossa www.uef.fi. Tutustu myös yliopistoon työyhteisönä ja työnantajana sekä työntekijöidemme uratarinoihin.
Työsopimuksen voimassaolo: määräaikainen työsopimus | Työsuhteen luonne: kokoaikainen/osa-aikainen | Paikkojen lukumäärä: 1 | Työllisyysaste: 100 | Paikkakunta: Kuopio | Maakunta: Pohjois-Savo | Maa: Finland | Ilmoitusnumero: | Julkaistu: 2023-04-11 | Haku päättyy: 2023-05-09
16.4.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3559459109
About the job
About The PerkinElmer Life Sciences and Diagnostics Company
The PerkinElmer Life Sciences and Diagnostics company – which is to be renamed during the second quarter of 2023 – provides end-to-end solutions that help scientists, researchers and clinicians better diagnose disease and discover new and more personalized drugs. Its dedicated team of 11,000 collaborates closely with commercial, government, academic and healthcare customers to deliver reagents, assays, instruments, automation, informatics and strategic services that accelerate workflows, deliver actionable insights and support improved decision making. The Company is also deeply committed to good corporate citizenship through dynamic ESG and sustainability programs.
The Company reported revenues of approximately $3.3 billion in 2022, serves customers in 190 countries, and is a component of the S&P 500 index.
PerkinElmer’s commitment to scientific innovation is at the heart of everything we do. In PerkinElmer meaningful work arises to a whole new level. When working with us you really have the opportunity to make a positive impact on babies’ and mothers‘ lives.
The Turku Site, with 650 employees, represents one of PerkinElmer’s major manufacturing and product development sites for newborn and maternal fetal health screening. As the global market leader in newborn screening, our solutions have tested over 560 million babies worldwide for life-threatening diseases.
About the Role
We are looking for a Principal Application Scientist specialized in Next Generation Sequencing to join our New Technologies R&D Team at Turku. NGS is an emerging trend in the field of screening for genetic disorders and this is an opportunity to shape the way this technology will be adopted for this novel use.
You are a highly independent technical expert on NGS working in the very beginning of the new product development pipeline. Your responsibility is to bring to life a Reproductive Health -related next generation sequencing product portfolio working closely together and in active communication with our business teams.
You have good networking skills and a passion for finding and collaborating with internal and external key opinion leaders in the field to find out the true customer needs. You are not afraid of the challenge of independently generating new ideas for novel products that also make commercial sense.
You have the responsibility of reporting on your work to the R&D and Business management. Internal marketing and driving of your ideas are also essential parts of your role.
The New Technologies team you will be a part of and working with is a cross-scientific group of independent and innovative experts in their fields tasked with generating new content for our new product development pipeline. The team provides its members with an excellent environment to reflect on ideas from many different technological points of view.
Role Requirements
- At least a MSc degree, Ph.D. preferred (role-relevant natural science)
- Minimum 5 years of experience life science, genomics with hands on experience with NGS assays
- Expert-level knowledge of NGS assay development – You have not only used NGS in your work but also designed e.g. targeted sequencing panels
- Proactive, independent, collaborative, enjoys networking with new people and a good team player
- Excellent written and verbal communication skills in English
- Experience within medical device / IVD industry or in a healthcare-related laboratory would be advantageous.
What We Offer
- Unique opportunity for truly meaningful work in positively impacting the world
- Be at the forefront of bringing NGS to a new field of use
- Development opportunities
- Positive and inspiring workplace with great co-workers
- Truly international working environment
If you feel you have the necessary skills and can see yourself as a part of our dedicated team of professionals, please apply now!
16.4.2023 | Avoimet työpaikat
https://www.linkedin.com/jobs/view/3570336814
About the job
Aalto University is where science and art meet technology and business. We shape a sustainable future by making research breakthroughs in and across our disciplines, sparking the game changers of tomorrow and creating novel solutions to major global challenges. Our community is made up of 13 000 students, 400 professors and close to 4 500 other faculty and staff working on our dynamic campus in Espoo, Greater Helsinki, Finland. Diversity is part of who we are, and we actively work to ensure our community’s diversity and inclusiveness. This is why we warmly encourage qualified candidates from all backgrounds to join our community.The School of Chemical Engineering is one of the six schools of Aalto University. It combines natural sciences and engineering in a unique way.The Department of Chemistry and Materials Science is looking for:
Postdoctoral Researcher to work on Nanoscience for biomedical applications
You will be developing superhydrophobic surfaces that will be used for single cell labelling and other biomedical applications. Your work will contribute towards the fields of biotechnology and nanoscience with the aim of improving medical diagnostics and single cell analysis.Your task will include developing and fabricating micro- and nanoscale superhydrophobic surfaces and devices. You will also work together with collaborators on developing the biomedical applications.
Your background and expertise
We are looking for a researcher who has passion to become a scientist working in an interdisciplinary topic combining micro-and nanoscience to biomedical and biomaterials science.We expect the candidate to have a doctoral degree and a strong background in one of the following. The other aspect can be learned on the job.
- Micro- and nanofabrication, for example optical or e-beam lithography, film deposition and etching. Typical characterization techniques, electron microscopy, goniometry.
- Expertise in working with single cell labelling or trapping (with droplet microfluidics or microwell arrays for example) or applications of superhydrophobic surfaces in biomedical science.
What We Offer
We offer an inspiring scientific environment. You would work in the facilities of Micronova in Otaniemi in a project headed by Dr. Ville Jokinen and you would become part of the Microfabrication group (led by professor Sami Franssila).You will also have an opportunity to be involved in collaboration with a research group in University of Helsinki (Faculty of Medicine) in order to develop the biomedical applications.The expected starting salary for a postdoctoral researcher is approximately 3570€/month. This is a fixed term position for 18 months.The contract includes occupational health benefits and Finland has a comprehensive social security system.Starting date will be late summer to fall of 2023. Exact date per agreement.
Ready to apply?
If you would like to join our community, please submit your application through our online recruiting system by using the link provided. Please include the following documents in English.Please note: Aalto University’s employees and visitors should apply for the position via our internal system Workday -> find jobs (not external aalto.fi webpage on open positions) by using their existing Workday user account.
- Motivation letter: free form 1 page letter where you describe yourself and why you are interested in this particular position.
- CV describing education and employment history
The call is open until Friday June 9th, 2023, but we will start reviewing and interviewing candidates immediately. Applications will be considered until the position is filled.If you have any questions, Dr. Jokinen is happy to give you more information about the position ville.p.jokine(a)aalto.fiAalto University reserves the right for justified reasons to leave the position open, to extend the application period and to consider candidates who have not submitted applications during the application period.Want to know more about us and your future colleagues? You can watch these videos: Aalto University – Towards a better world, Aalto People, and Shaping a Sustainable Future. You can also check out our webpage about Aalto and Finland: https://www.aalto.fi/en/services/welcome-to-aalto-university-and-finland-info-package and our new virtual campus experience: https://virtualtour.aalto.fi/.
About Finland
Finland is a great place for living with or without family – it is a safe, politically stable and well-organized Nordic society. Finland is consistently ranked high in quality of life and was just listed again as the happiest country in the world: https://worldhappiness.report/news/its-a-three-peat-finland-keeps-top-spot-as-happiest-country-in-world/. For more information about living in Finland: https://www.aalto.fi/en/careers-at-aalto/why-finlandMore about Aalto University:
Aalto.fitwitter.com/aaltouniversityfacebook.com/aaltouniversityinstagram.com/aaltouniversity