PhD positions are available at Nottingham Trent University. If you are interested in working on autotransporters or other bacterial cell surface components, please contact Jack C. Leo (jack.leo@ntu.ac.uk).
For more information, see https://www.ntu.ac.uk/research/research-degrees-at-ntu/phd-studentships
One postdoctoral fellow position is immediately available in the Pan laboratory in Department of Neurology and Molecular Pharmacology Program at Memorial Sloan-Kettering Cancer Center. The research in Pan’s lab focuses on molecular and cellular mechanisms of mu opioid actions using state-of-the-art molecular, biochemical, chemical and pharmacological approaches. providing the foundation of developing novel analgesic drugs for pain treatment (see Pharmacol Rev. 65:1257-1317, 2013; J Clin Invest. 125:2626-2630, 2015; J Clin Invest, 127:1561-1573, 2017).
The applicant(s) will participate in one or two of the projects in the following areas:
1) Investigating the mechanisms underlying alternative splicing of the mu opioid receptor gene (OPRM1) and its relevance to opioid pharmacology;
2) Mapping and characterizing mu agonist-induced receptor-protein interactions that contribute to opioid actions;
3) Determining molecular mechanisms of mu opioid-induced tolerance, respiratory depression and reward; and
4) Defining molecular mechanism of the novel analgesic drugs.
The laboratory will also provide a wealth of molecular, biochemical and pharmacological expertise to facilitate both research and career development. Highly-motivated candidates with experience in molecular biology and biochemistry or behavioral pharmacology are encouraged to apply. The positions are fully funded by the grants from NIDA. Salary will be commensurate with qualifications, laboratory experience and institutional guidelines.
Applicants interested in the position should send their curriculum vitae, along with contact information for three references, to Dr. Ying-Xian Pan (pany@mskcc.org).
We are looking for a bioinformatician to look after our database
consisting of health, sample, human genome and microbiome data.The
position is made available in the Finnish Health in Teens (Fin-HIT)
group, which is responsible for conducting a prospective
study of 11000 children and their parents (http://www.finhit.fi/).
Fin-HIT is based at the Folkhälsan Research Center
(https://www.folkhalsan.fi/en/research/ ) which is a part of “Samfundet
Folkhälsan i svenska Finland rf”, and which collaborates closely with
the University of Helsinki in the Meilahti Campus area. We are
collaborating with top researchers and research institutes in the world
to improve health and well-being.
Job description
The primary responsibilities of the position include:
• Managing genomic data repositories of variant data (16S rDNA gene sequencing, metagenome sequencing and genotyping chip data)
• Pre-processing and quality control of sequencing variant and genotyping chip data
• Execution and development of bioinformatics pipelines in high performance computing environmentand data analysis
• Managing databases with questionnaire and registry data
• Support research projects by preparing and delivering datasets on time
• Evaluate new methods and solutions to manipulate sequencing data
efficiently in distributed computing environments with a focus on data
protection
• Ensure data security
Qualification and experience
• Master’s degree in bioinformatics, computational biology, computer sciences, or equivalent
• Previous experience in database management or knowledge in SQL or any other relevant tools is preferred
• Capability to work effortlessly in Linux environment and at least intermediate programming skills
• Skills in statistical programs (R, SPSS) are required
• Solution-seeking, proactive and responsible way of working and keeping deadlines under pressure
• Previous experience with genomics data, data science or
distributed computing environments is appreciated but not required – yet
ability to learn new things quickly is essential
• Any experience in working with omics analysis (transcriptomics, proteomics, metabolomics) will be a plus.
• Experience working in public cloud environment is a plus
• Fluent in spoken and written English, our team is international so Finnish skills are not required
We are looking for a team player to support the multidisciplinary
research team. We offer a great opportunity to learn on genomics and
health sciences. We are a dynamic, vibrant and highly motivated team.
Our working culture is positive, flexible and encouraging.
Salary and contract
The Folkhälsan Research Center follows the collective agreement for
the private social service sector. The salary will be based on previous
qualifications, experience and performance in the position. A six-month
trial period will be applied. The position
is available immediately. The contract will be offered for two years,
and a possibility to pursue a PhD degree will be considered.
The application should include a cover letter, a CV, and contact
information of at least two referees. Please write your application in
English and send via email to Heli Viljakainen.
For further information contact group leader Docent Heli Viljakainen, heli.viljakainen(at)helsinki.fi or +358 50 4485660.
The deadline for application is January 20th, 2020.
In collaboration with the Nordic EMBL Partnership in Molecular Medicine and Helsinki Institute for Information Technology HIIT, FIMM announces the opening of the 2020 call for applications for Doctoral Students in Molecular Medicine, Bioinformatics, and Artificial Intelligence as part of the FIMM-EMBL International PhD recruitment and training program. In this program, outstanding doctoral students are recruited to the institute-level rotation program where they will work with two to three different research groups during a six to nine month period prior to matching to a research group in which they remain for their doctoral studies. The program provides an exciting opportunity to explore different research areas and working environments as well as to learn a variety of science and technologies, making connections within and beyond the institute.
The detailed call announcement can be found on the FIMM Open Positions page. The deadline for applications is 2 February 2020, and application instructions are available within the announcement.
We are recruiting a post doc with strong background in genetics and/or cell biology to our research team in Translational Research at the Department of Oral and Maxillofacial diseases, University of Helsinki (https://www.helsinki.fi/en/researchgroups/translational-research-on-oral-and-maxillofacial-sciences/research).
You will be part of multifaceted projects aimed at understanding the genetics and epigenetics of osteosarcoma and stem cells; developing 3D models for osteosarcoma in vitro diagnostics and applications of biomaterials. Experience with RNA sequencing, bioinformatics, biomaterials or tissue engineering is an advantage. Strong motivation to learn new techniques is necessary. The successful applicant must hold a PhD and post-doctoral experience. A six-month trial period will be effective in the beginning of a contract. In addition to English language, a strong command of Finnish language both spoken and written is required. The salary will be in accordance with the University salary system.
Responsibilities include:
The following documents must be attached to the application:
1) Motivation letter
2) CV, including publications, and the contact details of 2 – 3 referees
The position is for one year, with the possibility for extension. This
position will be filled as soon as the right person is found. Candidates
for the post are required to present their scientific work, experiences
and expectations from the future work during
the interview. Interviews will be held both in English and in Finnish.
For further information and application submission contact:
Bettina Mannerström, PhD, Adj. Professor, e-mail: bettina.mannerstrom@helsinki.fi
A postdoctoral position is available for a recent Ph.D. graduate to join the Contet laboratory at The Scripps Research Institute (La Jolla, CA) and study the neurobiological mechanisms of alcohol dependence. Our group investigates the proteins and neural circuits that are dysregulated by chronic alcohol exposure and their contribution to excessive drinking and other symptoms of alcohol dependence (www.contetlab.com). Previous experience with mouse behavior, stereotaxic surgeries, histology and molecular biology is desirable. Programming skills (MATLAB, R) would be advantageous. A high degree of self-motivation, meticulousness, critical thinking, efficient communication, and integrity are expected.
The Contet laboratory is part of TSRI Department of Molecular Medicine, Pearson Center for Alcoholism and Addiction Research, TSRI Alcohol Research Center, and TSRI Neuropsychopharmacology Training Program, which provide unique opportunities for multidisciplinary collaborations and outstanding resources for integrative training in the alcohol/drug addiction field.
This position offers California exempt salary (i.e., higher than NRSA stipend levels) and competitive health insurance from TSRI. US citizenship or permanent residency is required for appointment to our NIH-funded Institutional Training Grant. Individuals from underrepresented racial and ethnic groups are encouraged to apply.
Interested candidates should send their application material (CV, cover letter and contact information for three references) to Dr. Candice Contet (contet@scripps.edu).
The Department of Pharmacology and Toxicology at Virginia Commonwealth University invites applications for several tenure-eligible positions at the Assistant Professor, Associate Professor and Professor levels who are well established scholars working in the drug abuse field.
Candidates must have a PhD, MD/PhD or equivalent in pharmacology or a
closely-related field and at least three years of relevant postdoctoral
experience, for the assistant professor level, with increasing years of
experience expected for those wishing to be
considered at the associate professor or professor level.
Pharmacologists and other biologists with clear, established research
expertise in the area of drug abuse, utilizing classical or modern
neuroscience, molecular or behavioral techniques, are encouraged
to apply, as are synthetic organic chemists who have significant
expertise and funding in this area.
Applicants must have current and transferrable federal sponsored
research funding appropriate to complement and expand the existing
expertise of over 20 departmental faculty members working in this area.
The department has a long-standing federally funded training grant for
predoctoral and postdoctoral fellows and a P30 core center grant to help
support the scholarship of the faculty.
Candidates should also have a solid publication record via peer-reviewed journals, teaching experience at the graduate and/or professional school level, and evidence of service responsibilities, to include journal manuscript review, study section service, and/or service as an officer of a national scientific organization. Successful candidates must possess demonstrated experience working in and fostering a diverse faculty, staff, and student environment or a commitment to do so as a faculty member at Virginia Commonwealth University.
Application Process: Please apply via the Virginia Commonwealth University electronic recruiting system, eJobs, at https://www.vcujobs.com, by April 30, 2020. Search the keywords field for F61520, then submit a CV, cover letter (describing research interests), and (via the Other Documents section) the names and contact information for three professional references. Review of applications will begin immediately. Virginia Commonwealth University is an equal opportunity, affirmative action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.
Questions about these positions should be directed to Bill Dewey Chair Department of Pharmacology and Toxicology william.dewey@vcuhealth.org or (804) 827-0375
Aalto University is a community of bold thinkers where science and art meet technology and business. We are committed to identifying and solving grand societal challenges and building an innovative future. Aalto has six schools with nearly 11 000 students and a staff of more than 4000, of which 400 are professors. Our campus is located in Espoo, Finland.
Welcome to be the key person taking the newly established BioGarage forward!
BioGarage is an open laboratory for synthetic biology experimentation. At BioGarage students, researchers, startups and companies can test their ideas and cooperate in a low-threshold environment, connected to the Aalto Design Factory community. BioGarage will also serve as a multidisciplinary bridge between biology, engineering, and arts and inspire new ways of product development.
We are looking for a Laboratory manager for BioGarage, which starts its activities next spring at Aalto Design Factory.
The position is fixed-term for six months at the beginning with a possible continuation.
Your role and goals
As the BioGarage lab manager you will be:
· Managing and maintaining the laboratory
· Training and mentoring others for safe use of the lab and biotech protocols
· Facilitating the organization of courses at BioGarage
· Co-operating actively with other functions at Design Factory and the university
· Connecting to the international network of biohack labs
· Building and maintaining the BioGarage community and communicating about BioGarage operations and events
Your experience and ambitions
We look for candidates who have,
· Wide knowledge of microbiology, gene technology and biochemistry
· Mastery of safe and correct lab protocols
· Willingness to participate in community building and good communication skills
· M.Sc. in biotech or similar
Ready to apply?
If you want to join our community, please submit your application, including motivation letter and CV, through our recruitment system (“Apply for this job”).
If you wish to hear more about the position, you can reach out to Adjunct Professor Merja Penttilä (merja.penttila@vtt.fi) or in questions related to the recruitment process HR Coordinator Sanni Mero (sanni.mero@aalto.fi).
Deadline for applications is January 15, 2020.
Note, that the position may also be filled as part-time. Please, show your interest! University reserves the right for justified reasons to leave the position open, to extend the application period and to consider candidates who have not submitted applications during the application period.
https://www.sympahr.net/public/pq.aspx?391b98cd&lang=en-US
Lead of/
Are you ready to start an exciting venture into the world of gene therapy?
Does GMP, SOP, HOT, BMR, MVSS and WCB ring your bells? No? Don’t worry, you’ll learn! We are looking for new team members to Lead-positions in our manufacturing teams. Join us and you will soon know the meaning of those abbreviations and much more!
In order to succeed, you would need a MSc or a PhD degree in the fields of biosciences, cell biology, chemistry, biochemistry, biotechnology, pharmacy or any other related field of study or sufficient working experience from pharma industry. It is an advantage if you already have some experience of aseptic- or GMP-work, or you have knowledge of quality systems. If you would prefer the role where you are leading a team, you need to have interest and ability to manage people.
We hope that your way of working is systematic and precise, but you are open for changes and independent but a good team member. As a person, we would like you to be open-minded towards new challenges and goal-oriented. You also need to communicate fluently both in written and spoken English.
These positions are permanent and start preferably between February – April. Work at FinVector is done in shifts, but you would be mainly working during normal office hours.
We offer you an active and lively work community with highly skilled and experienced personnel in gene therapy manufacturing. Working with us, you are entitled to good employment benefits, such as extensive occupational health-care and we support your physical and cultural free-time activities. We provide you wide initial training and a warm welcome. FinVector is located in vibrant Kuopio, which offers a safe living environment, friendly atmosphere and clean nature.
Your main responsibilities as a Lead include project management of your own responsible area OR leading a team of Specialists. In both roles, you would also create documentation of GMP operations and get to know manufacturing operations hands-on.
Manufacturing at FinVector is done in cleanroom environment according to current GMP guidelines. Depending on your work experience and personal interest, you could be chosen to complement any of our existing teams: upstream, downstream, filling, development or buffer preparation team.
To find out more about the positions, contact HR Director Johanna Pirinen +358 44 556 5420 or johanna.pirinen@finvector.com preferably between Mon-Fri during office hours.
https://tyopaikat.oikotie.fi/avoimet-tyopaikat/scientist/1326165
KCT is seeking now for two enthusiastic and highly motivated (senior) scientists to join 2-year fixed term research projects. Minimal requirement is master degree in appropriate subject. The candidates will contribute to the projects experimentally and scientifically. They should have excellent written and oral English language skills for internal and scientific reporting as well the ability to work in a team oriented environment. The scientists will also participate in strategic discussions, national and international collaborations and coordinate project activities.
The first project is focusing on cardiovascular diseases. The second project aims to resolve some of the remaining challenges in viral gene delivery including controlled transgene expression. The candidates should have experience in virology, molecular and cell biology as well as recombinant DNA techniques. Background on viral-mediated gene delivery¸ cardiovascular diseases, especially in atherosclerosis, and gene therapy is preferred.
The responsibilities include: